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Aliases for ADAM3B Gene

Aliases for ADAM3B Gene

  • ADAM Metallopeptidase Domain 3B (Pseudogene) 2 3 5
  • A Disintegrin And Metalloproteinase Domain 3b (Cyritestin 2) 2 3
  • ADAM Metallopeptidase Domain 3B (Non-Functional) 2 3
  • Cyritestin 2 2 3
  • ADAM Metallopeptidase Domain 3B (Cyritestin 2) 3
  • CYRN2 3

External Ids for ADAM3B Gene

Previous HGNC Symbols for ADAM3B Gene

  • CYRN2

Previous GeneCards Identifiers for ADAM3B Gene

  • GC16U990017
  • GC16M049288
  • GC16M049329
  • GC16M048109
  • GC16M049551

Summaries for ADAM3B Gene

GeneCards Summary for ADAM3B Gene

ADAM3B (ADAM Metallopeptidase Domain 3B (Pseudogene)) is a Pseudogene.

Additional gene information for ADAM3B Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADAM3B Gene

Genomics for ADAM3B Gene

GeneHancer (GH) Regulatory Elements for ADAM3B Gene

Promoters and enhancers for ADAM3B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I049513 Enhancer 0.5 dbSUPER 0.8 +4.3 4316 2.2 SCRT1 CTCF ZNF366 SCRT2 ZSCAN4 KLF9 RAD21 ADAM3B LINC02179 ZNF423
GH16I049527 Enhancer 1 Ensembl ENCODE dbSUPER 0.4 -9.8 -9800 1.2 CTCF MEIS2 EBF1 NFIC ZFP36 RCOR1 ZBTB17 CHD2 ADAM3B GC16M049543 GC16M049542 ZNF423
GH16I049491 Enhancer 1 Ensembl ENCODE dbSUPER 0.3 +26.5 26491 1.5 CTCF USF1 MAX USF2 REST RAD21 YY1 GLIS2 GLIS1 PATZ1 ADAM3B LINC02179 GC16P049449 ZNF423
GH16I049484 Enhancer 0.8 Ensembl ENCODE 0.3 +34.0 34024 1.2 SP3 RXRA NRF1 NR2F2 SP1 ZNF366 POLR2A ZNF512 HNF4G HNF4A LINC02179 ADAM3B GC16P049449
GH16I049542 Enhancer 0.7 ENCODE dbSUPER 0.3 -24.3 -24313 1.7 POLR2A GLIS1 FOS ZIC2 GC16M049543 GC16M049542 ADAM3B ZNF423
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ADAM3B on UCSC Golden Path with GeneCards custom track

Genomic Locations for ADAM3B Gene

Genomic Locations for ADAM3B Gene
chr16:49,517,646-49,518,601
(GRCh38/hg38)
Size:
956 bases
Orientation:
Minus strand
chr16:49,551,557-49,552,512
(GRCh37/hg19)

Genomic View for ADAM3B Gene

Genes around ADAM3B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADAM3B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADAM3B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADAM3B Gene

Proteins for ADAM3B Gene

Post-translational modifications for ADAM3B Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADAM3B Gene

Domains & Families for ADAM3B Gene

Gene Families for ADAM3B Gene

Suggested Antigen Peptide Sequences for ADAM3B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ADAM3B: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for ADAM3B Gene

Function for ADAM3B Gene

Molecular function for ADAM3B Gene

GENATLAS Biochemistry:
a disintegrin and metalloprotease (inactive) domain 3B,cyritestin 2,membrane anchored cell surface adhesion protein and soluble form,expressed in the acrosome region of spermatids and spermatozoa,involved in sperm-egg fusion during fertilization

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ADAM3B Gene

Localization for ADAM3B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for ADAM3B Gene

Pathways & Interactions for ADAM3B Gene

SuperPathways for ADAM3B Gene

No Data Available

Interacting Proteins for ADAM3B Gene

Gene Ontology (GO) - Biological Process for ADAM3B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ADAM3B Gene

Drugs & Compounds for ADAM3B Gene

No Compound Related Data Available

Transcripts for ADAM3B Gene

mRNA/cDNA for ADAM3B Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ADAM3B Gene

No ASD Table

Relevant External Links for ADAM3B Gene

GeneLoc Exon Structure for
ADAM3B
ECgene alternative splicing isoforms for
ADAM3B

Expression for ADAM3B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ADAM3B Gene

NURSA nuclear receptor signaling pathways regulating expression of ADAM3B Gene:

ADAM3B
genes like me logo Genes that share expression patterns with ADAM3B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADAM3B Gene

Orthologs for ADAM3B Gene

Evolution for ADAM3B Gene

ENSEMBL:
Gene Tree for ADAM3B (if available)
TreeFam:
Gene Tree for ADAM3B (if available)

No data available for Orthologs for ADAM3B Gene

Paralogs for ADAM3B Gene

No data available for Paralogs for ADAM3B Gene

Variants for ADAM3B Gene

Additional Variant Information for ADAM3B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADAM3B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for ADAM3B Gene

Disorders for ADAM3B Gene

Additional Disease Information for ADAM3B

No disorders were found for ADAM3B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADAM3B Gene

Publications for ADAM3B Gene

  1. Human cyritestin genes (CYRN1 and CYRN2) are non-functional. (PMID: 11439107) Grzmil P … Engel W (The Biochemical journal 2001) 2 3 22 58
  2. Molecular cloning, chromosomal localization, and expression analysis of CYRN1 and CYRN2, two human genes coding for cyritestin, a sperm protein involved in gamete interaction. (PMID: 9502432) Adham IM … Engel W (DNA and cell biology 1998) 2 3 22 58
  3. Assignment of the germ cell cyritestin gene 2 (CYRN2) to human chromosome 16q12.1 by fluorescence in situ hybridization to 5-azacytidine induced, partially decondensed chromosomes. (PMID: 9284909) Koehler MR … Schmid M (Cytogenetics and cell genetics 1997) 2 3 22 58
  4. Evolutionary divergence and functions of the ADAM and ADAMTS gene families. (PMID: 19951893) Brocker CN … Nebert DW (Human genomics 2009) 3 58
  5. The gene for the human tMDC I sperm surface protein is non-functional: implications for its proposed role in mammalian sperm-egg recognition. (PMID: 9693117) Frayne J … Hall L (The Biochemical journal 1998) 3 58

Products for ADAM3B Gene

Sources for ADAM3B Gene

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