Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ADAM3B Gene

Aliases for ADAM3B Gene

  • ADAM Metallopeptidase Domain 3B (Pseudogene) 2 3 5
  • A Disintegrin And Metalloproteinase Domain 3b (Cyritestin 2) 2 3
  • ADAM Metallopeptidase Domain 3B (Non-Functional) 2 3
  • Cyritestin 2 2 3
  • ADAM Metallopeptidase Domain 3B (Cyritestin 2) 3
  • CYRN2 3

External Ids for ADAM3B Gene

Previous HGNC Symbols for ADAM3B Gene

  • CYRN2

Previous GeneCards Identifiers for ADAM3B Gene

  • GC16U990017
  • GC16M049288
  • GC16M049329
  • GC16M048109
  • GC16M049551

Summaries for ADAM3B Gene

GeneCards Summary for ADAM3B Gene

ADAM3B (ADAM Metallopeptidase Domain 3B (Pseudogene)) is a Pseudogene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADAM3B Gene

Genomics for ADAM3B Gene

Regulatory Elements for ADAM3B Gene

Enhancers for ADAM3B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G049513 0.7 dbSUPER 0.7 +4.3 4317 2.2 CTCF KLF1 PKNOX1 ZSCAN4 ZIC2 RAD21 ZFHX2 POLR2A ZNF366 SCRT2 ADAM3B LINC02179
GH16G049527 1.1 Ensembl ENCODE dbSUPER 0.4 -9.8 -9800 1.2 CTCF NFIC STAT1 PBX2 KDM1A EBF1 RAD21 EGR2 ADAM3B GC16M049542 GC16M049543
GH16G049491 1.2 Ensembl ENCODE dbSUPER 0.3 +26.5 26492 1.5 CTCF MAX RAD21 YY1 ZNF664 GLIS2 HDAC2 SMARCA4 GLIS1 MBD1 ADAM3B LINC02179
GH16G049508 0.8 FANTOM5 dbSUPER 0.4 +10.0 10023 0.1 SMARCA4 POLR2A GLIS1 FOS ZIC2 ZNF423 ADAM3B LINC02179
GH16G049484 0.9 Ensembl ENCODE 0.3 +34.0 34024 1.2 SP3 NRF1 NR2F2 SP1 ZNF366 ZNF512 NFYB HNF4G IRF1 HNF4A LINC02179 ADAM3B
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ADAM3B on UCSC Golden Path with GeneCards custom track

Genomic Location for ADAM3B Gene

49,517,646 bp from pter
49,518,601 bp from pter
956 bases
Minus strand

Genomic View for ADAM3B Gene

Genes around ADAM3B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADAM3B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADAM3B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADAM3B Gene

Proteins for ADAM3B Gene

Post-translational modifications for ADAM3B Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADAM3B Gene

Domains & Families for ADAM3B Gene

Gene Families for ADAM3B Gene

Suggested Antigen Peptide Sequences for ADAM3B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ADAM3B: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for ADAM3B Gene

Function for ADAM3B Gene

Molecular function for ADAM3B Gene

GENATLAS Biochemistry:
a disintegrin and metalloprotease (inactive) domain 3B,cyritestin 2,membrane anchored cell surface adhesion protein and soluble form,expressed in the acrosome region of spermatids and spermatozoa,involved in sperm-egg fusion during fertilization

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ADAM3B Gene

Localization for ADAM3B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ADAM3B Gene

Pathways & Interactions for ADAM3B Gene

SuperPathways for ADAM3B Gene

No Data Available

Interacting Proteins for ADAM3B Gene

Gene Ontology (GO) - Biological Process for ADAM3B Gene


No data available for Pathways by source and SIGNOR curated interactions for ADAM3B Gene

Drugs & Compounds for ADAM3B Gene

No Compound Related Data Available

Transcripts for ADAM3B Gene

mRNA/cDNA for ADAM3B Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ADAM3B Gene

No ASD Table

Relevant External Links for ADAM3B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ADAM3B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ADAM3B Gene

NURSA nuclear receptor signaling pathways regulating expression of ADAM3B Gene:

genes like me logo Genes that share expression patterns with ADAM3B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADAM3B Gene

Orthologs for ADAM3B Gene

Evolution for ADAM3B Gene

Gene Tree for ADAM3B (if available)
Gene Tree for ADAM3B (if available)

No data available for Orthologs for ADAM3B Gene

Paralogs for ADAM3B Gene

No data available for Paralogs for ADAM3B Gene

Variants for ADAM3B Gene

Sequence variations from dbSNP and Humsavar for ADAM3B Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1001375859 -- 49,518,657(+) GGTCT(A/G)TTTTC intron-variant, upstream-variant-2KB
rs1001426733 -- 49,518,355(+) ACAAA(C/G)AATAT intron-variant, nc-transcript-variant
rs1002219439 -- 49,519,786(+) GGAGA(G/T)AAAAT intron-variant, upstream-variant-2KB
rs1003222829 -- 49,518,319(+) ATACT(A/G)TTTCT intron-variant, nc-transcript-variant
rs10048122 -- 49,519,042(+) ctggg(G/T)gacag intron-variant, upstream-variant-2KB

Relevant External Links for ADAM3B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for ADAM3B Gene

Disorders for ADAM3B Gene

Relevant External Links for ADAM3B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ADAM3B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADAM3B Gene

Publications for ADAM3B Gene

  1. Human cyritestin genes (CYRN1 and CYRN2) are non-functional. (PMID: 11439107) Grzmil P. … Engel W. (Biochem. J. 2001) 2 3 22 64
  2. Molecular cloning, chromosomal localization, and expression analysis of CYRN1 and CYRN2, two human genes coding for cyritestin, a sperm protein involved in gamete interaction. (PMID: 9502432) Adham I.M. … Engel W. (DNA Cell Biol. 1998) 2 3 22 64
  3. Assignment of the germ cell cyritestin gene 2 (CYRN2) to human chromosome 16q12.1 by fluorescence in situ hybridization to 5-azacytidine induced, partially decondensed chromosomes. (PMID: 9284909) Koehler M.R. … Schmid M. (Cytogenet. Cell Genet. 1997) 2 3 22 64
  4. Evolutionary divergence and functions of the ADAM and ADAMTS gene families. (PMID: 19951893) Brocker C.N. … Nebert D.W. (Hum. Genomics 2009) 3 64
  5. The gene for the human tMDC I sperm surface protein is non-functional: implications for its proposed role in mammalian sperm-egg recognition. (PMID: 9693117) Frayne J. … Hall L. (Biochem. J. 1998) 3 64

Products for ADAM3B Gene

Sources for ADAM3B Gene

Loading form....