Aliases for ADAM3A Gene
Aliases for ADAM3A Gene
External Ids for ADAM3A Gene
- HGNC: 209
- Entrez Gene: 1587
- Ensembl: ENSG00000197475
Previous HGNC Symbols for ADAM3A Gene
- CYRN1
Previous GeneCards Identifiers for ADAM3A Gene
- GC08U990016
- GC08M039049
- GC08M039330
- GC08M039325
- GC08M037840
Summaries for ADAM3A Gene
GeneCards Summary for ADAM3A Gene
ADAM3A (ADAM Metallopeptidase Domain 3A (Pseudogene)) is a Pseudogene. Diseases associated with ADAM3A include Conjunctival Squamous Cell Carcinoma.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADAM3A Gene
Genomics for ADAM3A Gene
Regulatory Elements for ADAM3A Gene
Enhancers for ADAM3A Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH08G039581 | 0.6 | ENCODE | 8.1 | -59.0 | -58969 | 1.8 | PKNOX1 TAL1 TCF12 ARID1B NCOR1 SMARCA4 PBX2 KDM1A FOXP2 | ADAM5 LOC100130964 ADAM3A ADAM18 GC08P039555 |
| GH08G039534 | 0.8 | ENCODE | 0.4 | -12.2 | -12237 | 1.1 | HDAC1 LEF1 TAL1 TCF12 FOXM1 NCOR1 NR2F6 TRIM24 SMARCE1 MTA2 | ADAM3A GC08P039555 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ADAM3A on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ADAM3A gene promoter:
Regulatory Element Products
Genomic Location for ADAM3A Gene
- Chromosome:
- 8
- Start:
- 39,451,045 bp from pter
- End:
- 39,522,989 bp from pter
- Size:
- 71,945 bases
- Orientation:
- Minus strand
Genomic View for ADAM3A Gene
Genes around ADAM3A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p11.22 by Ensembl
- 8p11.22 by Entrez Gene
- 8p11.22 by HGNC
ADAM3A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ADAM3A Gene
Proteins for ADAM3A Gene
Post-translational modifications for ADAM3A Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for ADAM3A
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ADAM3A
- Origene Custom Protein Services for ADAM3A
- Search GeneTex for Proteins for ADAM3A
No data available for DME Specific Peptides for ADAM3A Gene
Domains & Families for ADAM3A Gene
Gene Families for ADAM3A Gene
- HGNC:
- IUPHAR :
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ADAM3A Gene
Function for ADAM3A Gene
Molecular function for ADAM3A Gene
- GENATLAS Biochemistry:
- a disintegrin and metalloprotease (inactive) domain 3A,cyritestin 1,membrane anchored cell surface adhesion protein and soluble form,expressed in the acrosome region of spermatids and spermatozoa,involved in sperm-egg fusion during fertilization
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ADAM3A
-
- Search ViGene Biosciences for ADAM3A
CRISPR Products
- Browse CRISPR knockouts for ADAM3A
miRNA Products
- Search ViGene Biosciences for ADAM3A
Inhibitory RNA Products
- Search ViGene Biosciences for ADAM3A
Clone Products
- GenScript: Custom all cDNA clones Services for ADAM3A
- VectorBuilder custom plasmid, inducible vectors for ADAM3A
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ADAM3A Gene
Localization for ADAM3A Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ADAM3A Gene
Transcripts for ADAM3A Gene
mRNA/cDNA for ADAM3A Gene
- (13) Additional mRNA sequences :
- (31) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ADAM3A Gene
CRISPR Products
- Browse CRISPR knockouts for ADAM3A
miRNA Products
- Search ViGene Biosciences for ADAM3A
Inhibitory RNA Products
- Search ViGene Biosciences for ADAM3A
Clone Products
- GenScript: Custom all cDNA clones Services for ADAM3A
- VectorBuilder custom plasmid, inducible vectors for ADAM3A
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ADAM3A
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - |
| ExUns: | 19 | ^ | 20 | ^ | 21 | ^ | 22 |
|---|---|---|---|---|---|---|---|
| SP1: | |||||||
| SP2: | |||||||
| SP3: | |||||||
| SP4: | |||||||
| SP5: | |||||||
| SP6: | |||||||
| SP7: |
Expression for ADAM3A Gene
mRNA differential expression in normal tissues according to GTEx for ADAM3A Gene
This gene is overexpressed in Testis (x52.7).
NURSA nuclear receptor signaling pathways regulating expression of ADAM3A Gene:
ADAM3ASOURCE GeneReport for Unigene cluster for ADAM3A Gene:
Hs.98848Primer Products
-
OriGene qPCR primer pairs for ADAM3A
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ADAM3A Gene
Orthologs for ADAM3A Gene
No data available for Orthologs for ADAM3A Gene
Paralogs for ADAM3A Gene
No data available for Paralogs for ADAM3A Gene
Variants for ADAM3A Gene
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000021991 | -- | 39,497,185(+) | GATTC(A/G)ACAGT | intron-variant | |
| rs1000176122 | -- | 39,486,379(+) | ATCTA(C/T)TTAGT | intron-variant | |
| rs1000294751 | -- | 39,497,365(+) | ATCTC(-/TT)TGTGC | intron-variant | |
| rs1000382711 | -- | 39,454,045(+) | TTTAC(A/G)TCACC | intron-variant | |
| rs1000383259 | -- | 39,478,111(+) | CTTTA(C/T)TGATA | intron-variant |
Relevant External Links for ADAM3A Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ADAM3A
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ADAM3A Gene
Disorders for ADAM3A Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| conjunctival squamous cell carcinoma |
|
|
Search ADAM3A in MalaCards
View complete list of genes associated with diseases
Relevant External Links for ADAM3A
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ADAM3A
No data available for UniProtKB/Swiss-Prot and Genatlas for ADAM3A Gene
Publications for ADAM3A Gene
- Human cyritestin genes (CYRN1 and CYRN2) are non-functional. (PMID: 11439107) Grzmil P. … Engel W. (Biochem. J. 2001) 2 3 22 64
- Molecular cloning, chromosomal localization, and expression analysis of CYRN1 and CYRN2, two human genes coding for cyritestin, a sperm protein involved in gamete interaction. (PMID: 9502432) Adham I.M. … Engel W. (DNA Cell Biol. 1998) 2 3 22 64
- A genome-wide study of inherited deletions identified two regions associated with nonsyndromic isolated oral clefts. (PMID: 25776870) Younkin S.G. … Ruczinski I. (Birth Defects Res. Part A Clin. Mol. Teratol. 2015) 3 64
- Identification of multiple DNA copy number alterations including frequent 8p11.22 amplification in conjunctival squamous cell carcinoma. (PMID: 25491297) Asnaghi L. … Eberhart C.G. (Invest. Ophthalmol. Vis. Sci. 2014) 3 64
- Association of ADAM33 gene polymorphisms with keloid scars in a northeastern Chinese population. (PMID: 25201121) Han J. … Hao L. (Cell. Physiol. Biochem. 2014) 3 64
Products for ADAM3A Gene
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- OriGene qPCR primer pairs for ADAM3A
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- Search GeneTex for Antibodies for ADAM3A
- Search GeneTex for Proteins for ADAM3A
- Search ViGene Biosciences for ADAM3A
- Cyagen custom Knockout/knockin (KOKI) mouse models for ADAM3A
- VectorBuilder custom plasmid, inducible vectors for ADAM3A
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ADAM3A
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ADAM3A Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
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- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
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- (115) ProteomicsDB
- (116) SCBT
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- (151) CIViC
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- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer