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Aliases for ADAM3A Gene

Aliases for ADAM3A Gene

  • ADAM Metallopeptidase Domain 3A (Pseudogene) 2 3 5
  • A Disintegrin And Metalloproteinase Domain 3a (Cyritestin 1) 2 3
  • ADAM Metallopeptidase Domain 3A, Pseudogene 2 3
  • Cyritestin 1 2 3
  • ADAM Metallopeptidase Domain 3A 2
  • ADAM3 3
  • TMDCI 3
  • CYRN1 3

External Ids for ADAM3A Gene

Previous HGNC Symbols for ADAM3A Gene

  • CYRN1

Previous GeneCards Identifiers for ADAM3A Gene

  • GC08U990016
  • GC08M039049
  • GC08M039330
  • GC08M039325
  • GC08M037840

Summaries for ADAM3A Gene

GeneCards Summary for ADAM3A Gene

ADAM3A (ADAM Metallopeptidase Domain 3A (Pseudogene)) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADAM3A Gene

Genomics for ADAM3A Gene

Regulatory Elements for ADAM3A Gene

Promoters for ADAM3A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ADAM3A on UCSC Golden Path with GeneCards custom track

Genomic Location for ADAM3A Gene

Chromosome:
8
Start:
39,451,045 bp from pter
End:
39,522,989 bp from pter
Size:
71,945 bases
Orientation:
Minus strand

Genomic View for ADAM3A Gene

Genes around ADAM3A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADAM3A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADAM3A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADAM3A Gene

Proteins for ADAM3A Gene

Post-translational modifications for ADAM3A Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADAM3A Gene

Domains & Families for ADAM3A Gene

Gene Families for ADAM3A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ADAM3A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ADAM3A Gene

Function for ADAM3A Gene

Molecular function for ADAM3A Gene

GENATLAS Biochemistry:
a disintegrin and metalloprotease (inactive) domain 3A,cyritestin 1,membrane anchored cell surface adhesion protein and soluble form,expressed in the acrosome region of spermatids and spermatozoa,involved in sperm-egg fusion during fertilization

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ADAM3A Gene

Localization for ADAM3A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ADAM3A Gene

Pathways & Interactions for ADAM3A Gene

SuperPathways for ADAM3A Gene

No Data Available

Interacting Proteins for ADAM3A Gene

Gene Ontology (GO) - Biological Process for ADAM3A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ADAM3A Gene

Drugs & Compounds for ADAM3A Gene

No Compound Related Data Available

Transcripts for ADAM3A Gene

Unigene Clusters for ADAM3A Gene

ADAM metallopeptidase domain 3A (pseudogene):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ADAM3A Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^
SP1: -
SP2:
SP3: - - -
SP4: - - -
SP5: - - - - -
SP6: - - - -
SP7: -

ExUns: 19 ^ 20 ^ 21 ^ 22
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:

Relevant External Links for ADAM3A Gene

GeneLoc Exon Structure for
ADAM3A
ECgene alternative splicing isoforms for
ADAM3A

Expression for ADAM3A Gene

mRNA expression in normal human tissues for ADAM3A Gene

mRNA differential expression in normal tissues according to GTEx for ADAM3A Gene

This gene is overexpressed in Testis (x52.7).

SOURCE GeneReport for Unigene cluster for ADAM3A Gene Hs.98848

genes like me logo Genes that share expression patterns with ADAM3A: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ADAM3A Gene

Orthologs for ADAM3A Gene

Evolution for ADAM3A Gene

ENSEMBL:
Gene Tree for ADAM3A (if available)
TreeFam:
Gene Tree for ADAM3A (if available)

No data available for Orthologs for ADAM3A Gene

Paralogs for ADAM3A Gene

No data available for Paralogs for ADAM3A Gene

Variants for ADAM3A Gene

Sequence variations from dbSNP and Humsavar for ADAM3A Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1132224 -- 39,492,007(-) CGATA(C/T)GATCC nc-transcript-variant
rs4076606 -- 39,471,431(+) ccgtg(C/G)ttcag intron-variant
rs4130307 -- 39,458,909(+) AGCTA(C/G)TTTAA intron-variant
rs6980729 -- 39,461,672(+) aaTTT(A/T)AAAAA intron-variant
rs6985822 -- 39,492,666(+) ATGAC(G/T)TATTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ADAM3A Gene

Variant ID Type Subtype PubMed ID
nsv428198 CNV Gain 18775914
dgv2227e1 CNV Complex 17122850
dgv2228e1 CNV Complex 17122850
dgv2229e1 CNV Complex 17122850
dgv7765n71 CNV Gain+Loss 21882294
dgv7766n71 CNV Loss 21882294
dgv7767n71 CNV Gain 21882294
dgv7768n71 CNV Loss 21882294
nsv890725 CNV Gain 21882294
dgv7769n71 CNV Loss 21882294
nsv527334 CNV Loss 19592680
dgv7770n71 CNV Gain 21882294
dgv146n17 CNV Loss 16327808
nsv508503 CNV Loss 20534489
nsv6163 CNV Loss 18451855
nsv820723 CNV Deletion 20802225
dgv1179n67 CNV Loss 20364138
nsv819496 CNV Gain 19587683
esv995573 CNV Deletion 20482838
dgv1282e199 CNV Deletion 23128226
dgv7772n71 CNV Gain+Loss 21882294
nsv890760 CNV Gain+Loss 21882294
esv21867 CNV Gain+Loss 19812545
nsv8331 CNV Gain+Loss 18304495
esv2736900 CNV Deletion 23290073
dgv181e180 CNV Loss 20482838
esv32816 CNV Loss 17666407
nsv433493 CNV Loss 18776910
esv2421469 CNV Deletion 20811451
nsv438050 CNV Loss 16468122
nsv515081 CNV Loss 21397061
dgv7773n71 CNV Loss 21882294
nsv442511 CNV CNV 18776908
nsv890774 CNV Gain 21882294
nsv511391 CNV Gain 21212237
dgv2230e1 CNV Complex 17122850
dgv2231e1 CNV Complex 17122850
dgv7774n71 CNV Loss 21882294
dgv7775n71 CNV Loss 21882294
nsv890806 CNV Gain+Loss 21882294
dgv2232e1 CNV Complex 17122850
dgv7776n71 CNV Gain 21882294
dgv7777n71 CNV Gain+Loss 21882294
dgv7778n71 CNV Gain 21882294
nsv890812 CNV Gain+Loss 21882294
nsv831297 CNV Gain 17160897
nsv433247 CNV Loss 18776910
dgv7779n71 CNV Gain+Loss 21882294
dgv147n17 CNV Loss 16327808
dgv7780n71 CNV Gain 21882294
nsv890825 CNV Gain 21882294
nsv890826 CNV Loss 21882294
esv2736901 CNV Deletion 23290073
nsv824608 CNV Gain 20364138
nsv824610 CNV Loss 20364138
dgv7781n71 CNV Loss 21882294
dgv7782n71 CNV Loss 21882294
dgv7783n71 CNV Loss 21882294
nsv824611 CNV Gain 20364138

Relevant External Links for ADAM3A Gene

HapMap Linkage Disequilibrium report
ADAM3A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ADAM3A Gene

Disorders for ADAM3A Gene

Relevant External Links for ADAM3A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ADAM3A

No disorders were found for ADAM3A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADAM3A Gene

Publications for ADAM3A Gene

  1. Human cyritestin genes (CYRN1 and CYRN2) are non-functional. (PMID: 11439107) Grzmil P. … Engel W. (Biochem. J. 2001) 2 3 23 67
  2. Molecular cloning, chromosomal localization, and expression analysis of CYRN1 and CYRN2, two human genes coding for cyritestin, a sperm protein involved in gamete interaction. (PMID: 9502432) Adham I.M. … Engel W. (DNA Cell Biol. 1998) 2 3 23
  3. Association of ADAM33 gene polymorphisms with keloid scars in a northeastern Chinese population. (PMID: 25201121) Han J. … Hao L. (Cell. Physiol. Biochem. 2014) 3
  4. Identification of multiple DNA copy number alterations including frequent 8p11.22 amplification in conjunctival squamous cell carcinoma. (PMID: 25491297) Asnaghi L. … Eberhart C.G. (Invest. Ophthalmol. Vis. Sci. 2014) 3
  5. Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas. (PMID: 21138945) Barrow J. … Grundy R. (Neuro-oncology 2011) 3

Products for ADAM3A Gene

Sources for ADAM3A Gene

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