ADAM33 Gene
protein-coding GIFtS: 57
GCID: GC20M003596
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|
ADAM metallopeptidase domain 33(Previous names: a disintegrin and metalloproteinase domain 33, chromosome...)
(Previous symbol: C20orf153)
| |
Aliases
for ADAM33 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ADAM Metallopeptidase Domain 331 2 | | DJ964F7.12 | | C20orf1531 2 3 | | DJ964F7.12 | | A Disintegrin And Metalloproteinase Domain 331 2 | | A Disintegrin And Metalloprotease 332 | | ADAM 332 3 | | Disintegrin And Metalloproteinase Domain-Containing Protein 332 | | DKFZp434K05211 | | Disintegrin And Reprolysin Metalloproteinase Family Protein2 | | Chromosome 20 Open Reading Frame 1531 | | EC 3.4.24.-3 |
Export aliases for ADAM33 gene to outside databasesPrevious GC identifers: GC20M003637 GC20M003643 |
Summaries
for ADAM33 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ADAM33:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family aremembrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety ofbiological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development,and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchialhyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.(provided by RefSeq, Jul 2008)
Gene Wiki entry for ADAM33
|
Genomic Views
for ADAM33 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ADAM33 gene promoter:
GR GR-beta p300 C/EBPalpha E47 CHOP-10 PPAR-gamma1 STAT3 GR-alpha PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ADAM33
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADAM33 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p13 Ensembl cytogenetic band: 20p13 HGNC cytogenetic band: 20p13ADAM33 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20M003596: view genomic region
(about GC identifiers)
Start:
|
3,648,612 bp from pter |
End:
|
3,662,893 bp from pter |
Size:
|
14,282 bases |
Orientation:
|
minus strand |
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Proteins
for ADAM33 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ADA33_HUMAN, Q9BZ11 (See
protein sequence)Recommended Name: Disintegrin and metalloproteinase domain-containing protein 33 precursor Size: 813 amino acids; 87739 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subcellular location: Membrane; Single-pass type I membrane protein
2 PDB 3D structures from  and Proteopedia  for ADAM33:1R54 (3D)
1R55 (3D)
Secondary accessions: A0A1K6 Q5JT75 Q5JT76 Q8N0W6Alternative splicing: 3 isoforms: Q9BZ11-1 Q9BZ11-2 Q9BZ11-3 (No experimental confirmation available. By similarity with mouse isoform)Explore the universe of human proteins at neXtProt for ADAM33: NX_Q9BZ11
Post-translational modifications:
The precursor is cleaved by a furin endopeptidase (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BZ11
ADAM33 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_079496.1 NP_694882.1
ENSEMBL proteins: ENSP00000348912 ENSP00000369190 ENSP00000322550
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table
ADAM33 for ontologies About GeneDecksing
ADAM33 Antibody Products:
Assay Products for ADAM33: |
Protein
Domains /
Families
for ADAM33 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ADAM33 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry Q9BZ11ProtoNet protein and cluster: Q9BZ11 3 Blocks protein families: IPB001762 Disintegrin IPB002870 Metalloendopeptidase M12B IPB006586 ADAM
UniProtKB/Swiss-Prot: ADA33_HUMAN, Q9BZ11Domain: The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting theenzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzymeSimilarity: Contains 1 disintegrin domainSimilarity: Contains 1 EGF-like domainSimilarity: Contains 1 peptidase M12B domain |
Function
for ADAM33 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Enzyme Number (IUBMB): EC 3.4.24.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADAM33 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADAM33 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ADAM33 (NM_025220) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADAM33 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADAM33 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADAM33 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ADAM33 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Adam33tm1.1Chch for ADAM33
2 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Adam33):
ADAM33 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ADAM33 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ADAM33
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
2 Interacting proteins for ADAM33 (Q9BZ112, 3 ENSP000003489124) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
ADAM33 for ontologies About GeneDecksing
|
Drugs & Compounds
for ADAM33 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ADAM33
1 DrugBank Compound for ADAM33 About this table
| Compound | Synonyms |
CAS
# | Type | Actions | PubMed Ids |
|---|
| Alpha-D-Mannose | -- | 3458-28-4 | target | -- | -- |
Search CenterWatch for drugs/clinical trials and news about ADAM33 / ADA33
|
Transcripts
for ADAM33 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ADAM33 gene (2 alternative transcripts): NM_025220.2 NM_153202.1 Unigene Cluster for ADAM33: ADAM metallopeptidase domain 33 Hs.173716 [show with all ESTs]Unigene Representative Sequence: AK2261486 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000466620(uc002wis.3) ENST00000356518(uc002wit.3 uc002wiu.3)
ENST00000483362(uc002wiq.1) ENST00000379861(uc002wir.1) ENST00000479330(uc002wiw.1)
ENST00000350009(uc010gba.1 uc010gbb.1 uc002wix.1 uc010zqg.1 uc010zqh.1 uc002wiy.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADAM33 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADAM33 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ADAM33 (NM_025220) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ADAM33 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADAM33 |
Additional cDNA sequence: AB055891.1 AF466287.1 AF466289.1 AK092627.1 AK095953.1 AK123015.1 AK126487.1 AK126498.1 AK226148.1 AK300429.1 AK304037.1 AY223850.1 AY223851.1 AY223852.1 AY223853.1 AY223854.1 AY223855.1 AY358314.1 BC062663.1 BC125112.1 BC125113.1 17 DOTS entries: DT.101984427 DT.97794136 DT.100665070 DT.100777324 DT.434730 DT.95227190 DT.120839396 DT.100022366 DT.120839384 DT.120839395 DT.100022367 DT.120839388 DT.120839376 DT.434823 DT.120839391 DT.120839397 DT.120839401 24/74 AceView cDNA sequences (see all 74): AY223852 BU150601 CD632594 BU783941 NM_153202 NM_025220 AF466289 AB055891 AI537771 AI370810 AW131070 AY223854 CD632575 AY223853 BM510563 CD632564 AY223851 AW594247 AF466287 BM511392 BQ694108 AK095953 BV206851 AK092627
GeneLoc Exon Structure
5/19 Alternative Splicing Database (ASD) splice patterns (SP) for ADAM33 (see all 19) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP2: | | | | | | | | | | | | | - | | | | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | | | | | - | | | | | | | | - | | | | | | - | | - | | - | | | | | | - | | - | | - | | - | | - | |
| ExUns: | 14b | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18a | · | 18b | · | 18c | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22a | · | 22b | · | 22c | ^ | 23 | ^ | 24a | · | 24b | · | 24c | · | 24d |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP4: | | | | | - | | | | | | - | | | | | | | | | | | | - | | - | | - | | | | | | | | | | | | | | |
| SP5: | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ADAM33
|
Expression
for ADAM33 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ADAM33 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTGCTGGCC
About this image
See ADAM33 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ADAM33
SOURCE GeneReport for Unigene cluster: Hs.173716
UniProtKB/Swiss-Prot: ADA33_HUMAN, Q9BZ11Tissue specificity: Expressed in all tissues, except liver, with high expression in placenta, lung, spleen and veins
SABiosciences Expression via Pathway-Focused PCR Array including ADAM33:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ADAM33
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ADAM33 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADAM33 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADAM33 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADAM33 |
Orthologs
for ADAM33 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ADAM33 gene from 4/19 species (see all 19) About this table
ENSEMBL Gene Tree for ADAM33 (if available)
TreeFam Gene Tree for ADAM33 (if available) |
Paralogs
for ADAM33 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ADAM33 gene
- ADAM72 ADAM192 ADAM122 ADAM232 ADAM112 ADAM302 ADAM222 ADAM282
- ADAM292 ADAM202 ADAM92 ADAM212 ADAM152 ADAM82
14 SIMAP similar genes for ADAM33 using alignment to 7 protein entries: ADA33_HUMAN (see all proteins):ADAMDEC1 ADAM19 ADAM12 ADAM23 ADAM28 ADAM21
ADAM22 ADAM7 ADAM2 ADAM30 ADAM9 ADAM11
ADAM15 ADAM18
ADAM33 for paralogs About GeneDecksing
|
Genomic Variants
for ADAM33 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ADAM33 (3648612 - 3662893 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ADAM33: --
Human Gene Mutation Database (HGMD): ADAM33
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ADAM33 |
|
Disorders
/ Diseases
for ADAM33 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ADAM33 for disorders About GeneDecksing
OMIM gene information: 607114
OMIM disorders: --
UniProtKB/Swiss-Prot: ADA33_HUMAN, Q9BZ11
Genetic variations in ADAM33 are associated with susceptibility to asthma (ASTHMA) [MIM:600807]. The mostcommon chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneousphenotype, largely attributed to the interactions among many genes and between these genes and the environment. It ischaracterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi
20/28  diseases for ADAM33 (see all 28): About MalaCardsasthma chronic obstructive pulmonary disease allergic rhinitis bronchial asthma
atopic dermatitis acute lymphoblastic leukemia macular degeneration pulmonary disease
lymphoblastic leukemia allergic asthma rhinitis bronchiolitis
dermatitis atopy hepatitis b rabies
copd polyposis gastric cancer psoriasis
1 disease from the University of Copenhagen DISEASES database for ADAM33:Asthma 6 Novoseek disease relationships for ADAM33 gene About this table
Genetic Association Database (GAD): ADAM33
Human Genome Epidemiology (HuGE) Navigator: ADAM33 (56 documents)
Export disorders for ADAM33 gene to outside databases
|
Publications
for ADAM33 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ADAM33 gene, integrated from 9 sources (see all 102):
(articles sorted by number of sources associating them with ADAM33) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. (PubMed id 12110844)1, 2, 4, 9 Van Eerdewegh P.... Keith T.P. (2002)
- Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activity. (PubMed id 11814695)1, 2, 3 Yoshinaka T.... Higashiyama S. (2002)
- ADAM33 polymorphism: association with bronchial hyper-responsiveness in Korean asthmatics. (PubMed id 15196271)1, 4, 9 Lee J.H....Shin H.D. (2004)
- Asthma is associated with single-nucleotide polymorphisms in ADAM33. (PubMed id 14720258)1, 4, 9 Werner M....Wjst M. (2004)
- Association of a disintegrin and metalloprotease 33 (ADAM33) gene with asthma in ethnically diverse populations. (PubMed id 14564349)1, 4, 9 Howard T.D....Meyers D.A. (2003)
- Polymorphisms in a disintegrin and metalloprotease 33 (ADAM33) predict impaired early-life lung function. (PubMed id 15805180)1, 4, 9 Simpson A....John S.L. (2005)
- A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population. (PubMed id 15879414)1, 4, 9 van Diemen C.C....Boezen H.M. (2005)
- Asthma severity and genetics in Taiwan. (PubMed id 15986064)1, 4, 9 Huang J.L. (2005)
- Positionally cloned asthma susceptibility gene polymorphisms and disease risk in the British 1958 Birth Cohort. (PubMed id 19237393)1, 2 Blakey J.D.... Hall I.P. (2009)
- ADAM33 haplotypes are associated with asthma in a large Australian population. (PubMed id 16773130)1, 2 Kedda M.A....Thompson P.J. (2006)
|
External Searches for ADAM33 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ADAM33 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ADAM33 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ADAM33 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ADAM33 | Pharmacogenomics, SNPs, Pathways | | NIEHS-SNPs | http://egp.gs.washington.edu/data/adam33/ |
|
| | |
About This Section
| Patent Information for ADAM33 gene:
Search GeneIP for patents involving ADAM33
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ADAM33 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for ADAM33 | | OriGene shRNA RFP for ADAM33 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ADAM33 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ADAM33 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ADAM33 | | OriGene 3'-UTR Clone for ADAM33 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ADAM33 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ADAM33 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ADAM33 | | OriGene Custom Protein Services for ADAM33 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ADAM33 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ADAM33 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ADAM33 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ADAM33 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ADAM33 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ADAM33 |
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| | | | Search Tocris compounds for ADAM33 |
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 | | | ADAM33 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ADAM33 |
|  |  |  | | | | ThermoFisher Antibodies for ADAM33 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ADAM33 |
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