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ADAM33 Gene

protein-coding   GIFtS: 65

GC20M003596
ADAM metallopeptidase domain 33
(Previous names: a disintegrin and metalloproteinase domain 33, chromosome 20 open reading frame 153 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: C20orf153)
Services    

Aliases &
Descriptions
for ADAM33

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
C20orf153 2
DJ964F7.1 2
DKFZp434K0521 1, 2
EC 3.4.24.- 3
FLJ35308 2
FLJ36751 2
MGC149823 2
MGC71889 2
OTTHUMP00000030126 2
dJ964F7.1 1
Descriptions
ADAM 33 3
ADAM metallopeptidase domain 33 2
a disintegrin and metalloprotease 33 2
a disintegrin and metalloproteinase domain 33 1, 2
chromosome 20 open reading frame 153 1
disintegrin and reprolysin metalloproteinase family protein 2
External Ids
HGNC: 154781
Entrez Gene: 803322
UniProtKB: Q9BZ113
Ensembl: ENSG000001494517
Search outside databases for aliases for ADAM33 gene

Previous GC identifers: GC20M003637 GC20M003643

Summaries
for ADAM33

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for ADAM33:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members
of this family are membrane-anchored proteins structurally related to snake venom disintegrins,
and have been implicated in a variety of biological processes involving cell-cell and cell-matrix
interactions, including fertilization, muscle development, and neurogenesis. This protein is a
type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative
splicing of this gene results in two transcript variants encoding different isoforms. [provided by
RefSeq]

Gene Wiki entry for ADAM33

Genomic Location
for ADAM33

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ADAM33 gene  

Entrez Gene cytogenetic band: 20p13   Ensembl cytogenetic band:  20p13   HGNC cytogenetic band: 20p13

ADAM33 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M003596:     (about GC identifiers)

Start:
 3,596,617 bp from pter
End:
 3,610,893 bp from pter
Size:
 14,277 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000020.9  NT_011387.8  

Proteins
for ADAM33

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: ADA33_HUMAN, Q9BZ11 (See protein sequence)
Recommended Name: Disintegrin and metalloproteinase domain-containing protein 33 precursor  
Size: 813 amino acids; 87739 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subcellular location: Membrane; Single-pass type I membrane protein
PDB structure from and Proteopedia :
1R54 (3D)    1R55 (3D)    
Secondary accessions: A0A1K6 Q5JT75 Q5JT76 Q8N0W6
Alternative splicing: 3 isoforms:  Q9BZ11-1   Q9BZ11-2   Q9BZ11-3   

Post-translational modifications:

  • The precursor is cleaved by a furin endopeptidase (By similarity)1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (2 alternative transcripts): 
    NP_079496.1  NP_694882.1  


    ENSEMBL proteins: 
    ENSP00000318839 ENSP00000369190 ENSP00000350730 ENSP00000353845 ENSP00000348912 ENSP00000322550 
    ENSP00000340571 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (ADAM33)
    Human Recombinant Proteins from Abnova (ADAM33)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    2 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020 membrane IEA--
    GO:0016021 integral to membrane NAS11814695
    About this table

    Antibodies for ADAM33: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for ADAM33
    R&D Systems Antibodies for ADAM33
    Antibodies from Abcam (ADAM33), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (ADAM33)
    Novus Biologicals Antibodies for ADAM33

    Assays for ADAM33: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for ADAM33

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/11 InterPro domains/families (see all 11 ):
     IPR018358 Disintegrin_CS
     IPR001818 Pept_M10A_M12B
     IPR006586 ADAM_Cys-rich
     IPR001762 Blood-coag_inhib_Disintegrin
     IPR000742 EGF_3


       GeneDecks  ADAM33 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q9BZ11

    ProtoNet protein and cluster: Q9BZ11

    3 Blocks protein families:
    IPB001762 Disintegrin
    IPB002870 Metalloendopeptidase M12B
    IPB006586 ADAM


    UniProtKB/Swiss-Prot: ADA33_HUMAN, Q9BZ11
    Domain: The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion,
    thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the
    activation-peptide release activates the enzyme
    Similarity: Contains 1 disintegrin domain
    Similarity: Contains 1 EGF-like domain
    Similarity: Contains 1 peptidase M12B domain

    Gene Function
    for ADAM33

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (ADAM33)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADAM33)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_153202

                  Applied Biosystems Silencer® siRNAs for ADAM33

                  Sigma-Aldrich siRNA and siRNA Panels for ADAM33  
                         Sigma-Aldrich shRNA for ADAM33  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for ADAM33
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_025220
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_025220
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_025220 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_025220

    2 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Adam33):

    no phenotypic analysisnormal

    4 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004222 metalloendopeptidase activity NAS11814695
    GO:0008233 peptidase activity IEA--
    GO:0008270 zinc ion binding NAS11814695
    GO:0046872 metal ion binding IEA--
    About this table

    Pathways & Interactions
    for ADAM33

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    1 Invitrogen iPath™ Online BioAtlas - Pathway for ADAM33 (Maps provided by GeneGo):
     The role of amyloid proteins in cell adhesion

       GeneDecks  ADAM33 for the pathways selected above  
    About GeneDecksing

     Gene Network CentralTM Interacting Genes and Proteins Network for  ADAM33 


    5/8 Interacting proteins for ADAM33 (ENSP000003489123 Q9BZ112) via UniProtKB, MINT, and/or STRING (see all 8 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBQLN4Q9NRR52MINT-2876787
    PHF11ENSP000003675703STRING (score=.901)
    NPSR1ENSP000003709503STRING (score=.894)
    GPR44ENSP000003328123STRING (score=.788)
    IL4RENSP000001706303STRING (score=.774)
    About this table

    1 Gene Ontology (GO) biological process term (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508 proteolysis NAS11814695
    About this table

    Drugs & Compounds
    for ADAM33

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Enzo Life Sciences drugs & compounds for ADAM33
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for ADAM33

    Transcripts
    for ADAM33

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (ADAM33)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ADAM33)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_153202

                  Sigma-Aldrich siRNA and siRNA Panels for ADAM33  
                         Sigma-Aldrich shRNA for ADAM33  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_025220  NM_153202  

    REFSEQ mRNAs for ADAM33 gene (2 alternative transcripts): 

    NM_025220.2   NM_153202.1   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_025220  NM_153202  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_025220
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_025220
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_025220 

    Additional cDNA sequence: 

    AB055891.1 AF466287.1 AF466289.1 AK092627.1 AK095953.1 AK123015.1 AK126487.1 AK126498.1 
    AK226148.1 AK300429.1 AK304037.1 AY223850.1 AY223851.1 AY223852.1 AY223853.1 AY223854.1 
    AY223855.1 AY358314.1 BC062663.1 BC125112.1 BC125113.1 

    17 DOTS entries:

    DT.101984427  DT.97794136  DT.100665070  DT.100777324  DT.434730  DT.95227190  DT.120839396  DT.100022366 
    DT.120839384  DT.120839395  DT.100022367  DT.120839388  DT.120839376  DT.434823  DT.120839391  DT.120839397 
    DT.120839401 

    24/74 AceView cDNA sequences (see all 74 ):

    NM_025220 AW131070 AI537771 CD632594 AY223852 BM510563 AW594247 AY223853 
    AY223851 AB055891 AF466289 BU150601 NM_153202 BU783941 CD632564 CD632575 
    AI370810 AF466287 AY223854 T83640 CD632591 BV196131 BC062663 BQ694108 

    highest scoring ESTs for ADAM33:

    AB055891 AF466287 AF466289 AK095953 AK123015 AK126487 AK126498 AY358314 CD632573 AA197050 

    Unigene Cluster for ADAM33:

    ADAM metallopeptidase domain 33
    Hs.173716  [show with all ESTs]
    Unigene Representative Sequence: AK226148


    GeneLoc Exon Structure

    5/19 Alternative Splicing Database (ASD) splice patterns (SP) for ADAM33 (see all 19 )

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a ·
    SP1:                                      -                 -                 -     -                                                                       -   
    SP2:                                      -                 -                 -     -                                                                       -   
    SP3:                                                                                                                                                            
    SP4:                                      -                 -                                                                                                   
    SP5:                                      -                 -                       -                 -     -     -                 -     -     -     -     -   

    ExUns: 14b ^ 15 ^ 16a · 16b ^ 17 ^ 18a · 18b · 18c ^ 19 ^ 20 ^ 21a · 21b ^ 22a · 22b · 22c ^ 23 ^ 24a · 24b · 24c · 24d
    SP1:              -                                                     -     -     -                                       
    SP2:              -                                                     -     -     -                                       
    SP3:              -                                                     -     -     -                                       
    SP4:              -                 -                                   -     -     -                                       
    SP5:  -     -     -     -     -                                               -                                             

    About this scheme

    ECgene alternative splicing isoforms for ADAM33

    7 Ensembl transcripts including schematic representations:
    ENST00000322570  ENST00000379861  ENST00000358035  ENST00000360630  ENST00000356518  ENST00000350009  
    ENST00000339622  

    Expression
    for ADAM33

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ADAM33 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ADAM33

    1 / 2 / 3

    5 probe-sets matching ADAM33 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    90688_r_at2, 3 U95-E 1 1.00 1.00 1.00 1.00 T98467 0.60 1.00 0.82 1

    		233868_x_at2, 3 U133-B 1 1.00 1.00 -- -- AL117415 0.20 1.00 0.72 1

    		232570_s_at2 U133-B 1 1.00 1.00 -- -- -- -- -- -- --

    		233868_x_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		232570_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  ADAM33 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: ACTGCTGGCC

    SOURCE GeneReport for Unigene cluster: Hs.173716

    UniProtKB/Swiss-Prot: ADA33_HUMAN, Q9BZ11
    Tissue specificity: Expressed in all tissues, except liver, with high expression in placenta, lung,
    spleen and veins

    Orthologs
    for ADAM33

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for ADAM33 gene from 5/8 species (see all 8 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 ADAM331   -- ADAM metallopeptidase domain 33 83.49(n)
    78.14(a)    		 485795  XM_542918.2  XP_542918.2 
    cow
    (Bos taurus)    		 ADAM331   -- ADAM metallopeptidase domain 33 82.08(n)
    76.33(a)    		 523627  XM_601929.3  XP_601929.2 
    rat
    (Rattus norvegicus)    		 Adam331   -- ADAM metallopeptidase domain 33 78.3(n)
    73.02(a)    		 311425  XM_230607.4  XP_230607.4 
    mouse
    (Mus musculus)    		 Adam331, 5 2 (73.90 cM)5
    		 a disintegrin and metallopeptidase domain 331, 5 78.4(n)1
    72.73(a)1    		 1107511  NM_033615.11  NP_291093.11 
     AA1663925  AB0596325  (see all 20)
    chicken
    (Gallus gallus)    		 ADAM331   -- ADAM metallopeptidase domain 33 65.87(n)
    58.67(a)    		 422948  XM_420886.2  XP_420886.2 
    About this table        Species with no ortholog for ADAM33

    ENSEMBL Gene Tree for ADAM33

    Paralogs
    for ADAM33

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for ADAM33 gene
    ADAM192  ADAM122  ADAM152  

    SNPs/Variants
    for ADAM33

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/211 NCBI SNPs in ADAM33 are shown (see all 211 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 93)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 20 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs6770441,2
    		A,C,F,H,O3597431(+) TTCTAA/GTGTGG 2 -- ut3114Minor allele frequency- G:0.24EA NA EU WA NS 2456
    rs39184001,2
    		A,C,F,H3597463(-) AGCTTC/TGACCC 2 -- ut319Minor allele frequency- T:0.11EU EA WA NS 600
    rs27870931,2
    		A,C,F,H3596462(+) TGCCAT/CCTAGG 2 -- ng5113Minor allele frequency- C:0.30EU EA WA NS 1016
    rs5126251,2
    		A,C,F,H3596378(+) AGGGAG/AGCAGG 2 -- ng5110Minor allele frequency- A:0.32MN EU EA WA NS 794
    rs22800911,2
    		C,F,H3598234(+) ACTCCA/GTGGGG 2 M/T mis111Minor allele frequency- G:0.12EA EU WA NA NS 2164
    --
    rs5970401,2
    		A,C,F3611913(+) gctggG/Cattac 2 -- ng315Minor allele frequency- C:0.04NS 168
    --
    rs5171551,2
    		A,C,F3596877(+) accccG/Agcttc 2 -- ut315Minor allele frequency- A:0.08NS 164
    rs119052331,2
    		C,F,H3597176(+) GTGGAC/TTCAGT 2 -- ut31 ese39Minor allele frequency- T:0.01EU EA WA NS 600
    rs37466311,2
    		C,F,H3597140(+) GTTTGT/CTTGCA 2 -- ut3119Minor allele frequency- C:0.12EA NA EU WA NS 2830
    rs27870941,2
    		A,C,F3597161(+) AGGCTG/CCAGGG 2 -- ut31 ese310Minor allele frequency- C:0.33EA NA NS 2046
    About this table

    HapMap Linkage Disequilibrium images for ADAM33 (up to first 250kb)

    Disorders & Mutations
    for ADAM33

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 607114

    UniProtKB/Swiss-Prot: ADA33_HUMAN, Q9BZ11
  • Defects in ADAM33 may be a cause of susceptibility to asthma

    • 6 Novoseek disease relationships for ADAM33 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    asthma 70.61 85 16387804 (8), 14564349 (5), 17208589 (4), 16839403 (4) (see all 26)
    asthma childhood 56.42 4 16784537 (2), 16650044 (2)
    asthma allergic 48.71 3 18778489 (2), 16784537 (1)
    airway obstruction 39.38 1 17088949 (1)
    pulmonary disease chronic obstructive 28.67 1 15879414 (1)
    inflammation 3.34 3 17090574 (1), 17088949 (1), 17878941 (1)
    About this table

    1 PharmGKB disease relationship for ADAM33 gene
    Disease PharmGKB Relations PubMed IDs for articles supporting these relationships
    AsthmaGN  12958057
    About this table

    Genetic Association Database: ADAM33
    Human Genome Epidemiology Navigator: ADAM33 (35 documents)

    Medical News
    for ADAM33

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for ADAM33

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/71 PubMed articles for ADAM33 gene (see all 71 ):

    Search for ADAM33

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing ADAM33

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 80332 HGNC: 15478 AceView: ADAM33 Ensembl:ENSG00000149451 euGenes: HUgn80332
    ECgene: ADAM33 H-InvDB: ADAM33

    Other Databases showing ADAM33

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing ADAM33

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    NIEHS-SNPshttp://egp.gs.washington.edu/data/adam33/

    Licensable Technologies
    for ADAM33

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for ADAM33

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ADAM33:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ADAM33-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for ADAM33 Antibodies for ADAM33
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for ADAM33 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (ADAM33)
     Antibodies (ADAM33)
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     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (ADAM33)
     Antibodies (ADAM33)
     Search OriGene for ADAM33
     Search Tocris compounds for ADAM33




     Drugs for ADAM33
     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for ADAM33

    GeneCards Homepage    -    Last full update: 1 Jul 2009        Incremental update: 13 Oct 2009

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