Aliases for ADAM30 Gene
External Ids for ADAM30 Gene
Previous GeneCards Identifiers for ADAM30 Gene
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is testis-specific and contains a polymorphic region, resulting in isoforms with varying numbers of C-terminal repeats. [provided by RefSeq, Jul 2008]
GeneCards Summary for ADAM30 Gene
ADAM30 (ADAM Metallopeptidase Domain 30) is a Protein Coding gene. Among its related pathways are Reproduction. GO annotations related to this gene include metalloendopeptidase activity and metallopeptidase activity. An important paralog of this gene is ADAM21.
UniProtKB/Swiss-Prot for ADAM30 Gene
Plays a role in lysosomal amyloid precursor protein (APP) processing by cleaving and activating CTSD/cathepsin D which leads to APP degradation (PubMed:27333034).