Aliases for ADAM21 Gene
External Ids for ADAM21 Gene
Previous GeneCards Identifiers for ADAM21 Gene
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The expression of this gene expression is testis-specific. [provided by RefSeq, May 2011]
GeneCards Summary for ADAM21 Gene
ADAM21 (ADAM Metallopeptidase Domain 21) is a Protein Coding gene. Among its related pathways are Fertilization. GO annotations related to this gene include metalloendopeptidase activity and metallopeptidase activity. An important paralog of this gene is ADAM20.
UniProtKB/Swiss-Prot for ADAM21 Gene
May be involved in sperm maturation and/or fertilization. May also be involved in epithelia functions associated with establishing and maintaining gradients of ions or nutrients.