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Aliases for ADAM1A Gene

Aliases for ADAM1A Gene

  • ADAM Metallopeptidase Domain 1A (Pseudogene) 2 3 5
  • A Disintegrin And Metalloproteinase Domain 1 (Fertilin Alpha) Pseudogene 2 3
  • ADAM Metallopeptidase Domain 1, Pseudogene 2 3
  • Fertilin Alpha 2 3
  • A Disintegrin And Metalloproteinase Domain 1 ( Fertilin Alpha) 3
  • ADAM Metallopeptidase Domain 1 (Fertilin Alpha) Pseudogene 3
  • ADAM Metallopeptidase Domain 1A, Pseudogene 2
  • ADAM1P 3
  • PH-30a 3
  • FTNAP 3
  • ADAM1 3
  • Ftna 3

External Ids for ADAM1A Gene

Previous HGNC Symbols for ADAM1A Gene

  • ADAM1

Previous GeneCards Identifiers for ADAM1A Gene

  • GC12P112340
  • GC12P112344
  • GC12P112351
  • GC12P112357

Summaries for ADAM1A Gene

GeneCards Summary for ADAM1A Gene

ADAM1A (ADAM Metallopeptidase Domain 1A (Pseudogene)) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ADAM1A Gene

Genomics for ADAM1A Gene

Regulatory Elements for ADAM1A Gene

Enhancers for ADAM1A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12F111424 1.6 FANTOM5 Ensembl ENCODE 35.7 -460.9 -460888 27.9 HDGF PKNOX1 ATF1 WRNIP1 SIN3A ZNF2 YY1 ZNF121 GLIS2 ZNF143 ADAM1A SH2B3 PCNPP1 FAM216A FAM109A MIR6861 MAPKAPK5 ALDH2 TMEM116 BRAP
GH12F111150 0.4 Ensembl 32.1 -748.6 -748563 0.2 ZNF493 ZFP64 ZNF140 ZNF266 ZNF101 ZFHX2 ZNF354C SCRT2 KLF7 ZNF433 MAPKAPK5 PCNPP1 ADAM1A NAA25 HSPA8P14 ANAPC7 FAM216A CUX2 TRAFD1 GC12M111175
GH12F112115 1.2 FANTOM5 Ensembl ENCODE 28.4 +218.0 218038 2.6 HDGF ATF1 PKNOX1 ARNT ARID4B FEZF1 DMAP1 ZNF48 ZNF121 GLIS2 ADAM1A MIR6861 TMEM116 TRAFD1 ALDH2 GC12P112109
GH12F112417 0.2 ENCODE 21.6 +520.1 520087 2.4 HDGF PKNOX1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ADAM1A DDX54 MAPKAPK5 TMEM116 GC12M112409 RPL6
GH12F112352 1.1 Ensembl ENCODE 21.4 +454.8 454772 1.9 TBP PKNOX1 ZSCAN9 CHAMP1 RARA SLC30A9 GTF3C2 ZNF143 FOS MIER1 TMEM116 ADAM1A MAPKAPK5 HSPA8P14 DDX54 MIR6861 GC12P112348 GC12P112372
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ADAM1A on UCSC Golden Path with GeneCards custom track

Genomic Location for ADAM1A Gene

Chromosome:
12
Start:
111,899,063 bp from pter
End:
111,901,902 bp from pter
Size:
2,840 bases
Orientation:
Plus strand

Genomic View for ADAM1A Gene

Genes around ADAM1A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ADAM1A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ADAM1A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ADAM1A Gene

Proteins for ADAM1A Gene

Post-translational modifications for ADAM1A Gene

No Post-translational modifications

No data available for DME Specific Peptides for ADAM1A Gene

Domains & Families for ADAM1A Gene

Gene Families for ADAM1A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ADAM1A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ADAM1A Gene

Function for ADAM1A Gene

Animal Model Products

miRNA for ADAM1A Gene

miRTarBase miRNAs that target ADAM1A

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ADAM1A Gene

Localization for ADAM1A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ADAM1A Gene

Pathways & Interactions for ADAM1A Gene

SuperPathways for ADAM1A Gene

No Data Available

Interacting Proteins for ADAM1A Gene

Gene Ontology (GO) - Biological Process for ADAM1A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ADAM1A Gene

Transcripts for ADAM1A Gene

mRNA/cDNA for ADAM1A Gene

(1) Additional mRNA sequences :
(32) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ADAM1A Gene

ADAM metallopeptidase domain 1A, pseudogene:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ADAM1A Gene

No ASD Table

Relevant External Links for ADAM1A Gene

GeneLoc Exon Structure for
ADAM1A
ECgene alternative splicing isoforms for
ADAM1A

Expression for ADAM1A Gene

mRNA expression in normal human tissues for ADAM1A Gene

NURSA nuclear receptor signaling pathways regulating expression of ADAM1A Gene:

ADAM1A

SOURCE GeneReport for Unigene cluster for ADAM1A Gene:

Hs.661708
genes like me logo Genes that share expression patterns with ADAM1A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ADAM1A Gene

Orthologs for ADAM1A Gene

Evolution for ADAM1A Gene

ENSEMBL:
Gene Tree for ADAM1A (if available)
TreeFam:
Gene Tree for ADAM1A (if available)

No data available for Orthologs for ADAM1A Gene

Paralogs for ADAM1A Gene

No data available for Paralogs for ADAM1A Gene

Variants for ADAM1A Gene

Sequence variations from dbSNP and Humsavar for ADAM1A Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs10557147 -- 111,901,291(+) TTGTA(-/AT)GATTT intron-variant, nc-transcript-variant, utr-variant-3-prime
rs10732233 -- 111,898,890(+) ATTAA(C/T)GGATA intron-variant, upstream-variant-2KB, utr-variant-3-prime
rs10849981 -- 111,897,413(+) AAATA(A/T)GTTTC intron-variant, upstream-variant-2KB, utr-variant-3-prime
rs10849982 -- 111,897,735(+) TATCT(A/G)TATTA intron-variant, upstream-variant-2KB, utr-variant-3-prime
rs11066072 -- 111,900,400(+) CCACT(C/T)GGCCT intron-variant, nc-transcript-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ADAM1A Gene

Variant ID Type Subtype PubMed ID
esv1010936 CNV deletion 20482838
nsv1044606 CNV gain 25217958
nsv1045488 CNV gain 25217958

Relevant External Links for ADAM1A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ADAM1A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ADAM1A Gene

Disorders for ADAM1A Gene

Relevant External Links for ADAM1A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ADAM1A

No disorders were found for ADAM1A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ADAM1A Gene

Publications for ADAM1A Gene

  1. The human fertilin alpha gene is non-functional: implications for its proposed role in fertilization. (PMID: 9032439) Jury J.A. … Hall L. (Biochem. J. 1997) 2 3 22 64
  2. The transmembrane homotrimer of ADAM 1 in model lipid bilayers. (PMID: 17189481) Gan S.W. … Torres J. (Protein Sci. 2007) 22 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. The mechanism of sperm-oocyte fusion in mammals. (PMID: 15047933) Kaji K. … Kudo A. (Reproduction 2004) 22 64
  5. Positive selection within sperm-egg adhesion domains of fertilin: an ADAM gene with a potential role in fertilization. (PMID: 12519902) Civetta A. (Mol. Biol. Evol. 2003) 22 64

Products for ADAM1A Gene

Sources for ADAM1A Gene

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