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ACYP2 Gene

protein-coding   GIFtS: 60
GCID: GC02P054199

Acylphosphatase 2, Muscle Type

  Search for ACYP2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Acylphosphatase 2, Muscle Type1 2     EC 3.6.1.73 8
ACYP2 3 5     ACYM2
Acylphosphatase, Muscle Type Isozyme2 3     acylphosphatase-22
Acylphosphate Phosphohydrolase 22 3     

External Ids:    HGNC: 1801   Entrez Gene: 982   Ensembl: ENSG000001706347   OMIM: 1025955   UniProtKB: P146213   

Export aliases for ACYP2 gene to outside databases

Previous GC identifers: GC02P054380 GC02P054528 GC02P054155 GC02P054316 GC02P054254 GC02P054342


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ACYP2 Gene:
Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the
Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle
acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the
muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. (provided by
RefSeq, Jul 2008)

GeneCards Summary for ACYP2 Gene:
ACYP2 (acylphosphatase 2, muscle type) is a protein-coding gene. GO annotations related to this gene include acylphosphatase activity. An important paralog of this gene is ACYP1.

UniProtKB/Swiss-Prot: ACYP2_HUMAN, P14621
Function: Its physiological role is not yet clear

Gene Wiki entry for ACYP2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_022184.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the ACYP2 gene promoter:
         Bach1   FOXF2   NF-E2 p45   C/EBPalpha   CHOP-10   FOXC1   FOXJ2 (long isoform)   FOXJ2   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidACYP2 promoter sequence
   Search Chromatin IP Primers for ACYP2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ACYP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p16.2   Ensembl cytogenetic band:  2p16.2   HGNC cytogenetic band: 2p16.2

ACYP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACYP2 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P054199:  view genomic region     (about GC identifiers)

Start:
54,197,975 bp from pter      End:
54,532,437 bp from pter
Size:
334,463 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ACYP2_HUMAN, P14621 (See protein sequence)
Recommended Name: Acylphosphatase-2  
Size: 99 amino acids; 11140 Da

Explore the universe of human proteins at neXtProt for ACYP2: NX_P14621

Explore proteomics data for ACYP2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 3 DME Specific Peptides for ACYP2 (P14621)
     SVDYEVFG  GTVTGQVQGPE  FSNEKTISKLEYS 


    See ACYP2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_612457.1  
    ENSEMBL proteins: 
     ENSP00000475424   ENSP00000475986   ENSP00000475658   ENSP00000385674   ENSP00000306448  
     ENSP00000378161   ENSP00000475312   ENSP00000475333  

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    Sino Biological Recombinant Protein for ACYP2
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    Cloud-Clone Corp. Proteins for ACYP2

     
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    ACYP2 Antibody Products:

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    Search eBioscience for ELISAs for ACYP2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR027147 Acylphosphatase-2
     IPR017968 Acylphosphatase_CS
     IPR001792 Acylphosphatase-like_dom
     IPR020456 Acylphosphatase

    Graphical View of Domain Structure for InterPro Entry P14621

    ProtoNet protein and cluster: P14621

    1 Blocks protein domain: IPB001792 Acylphosphatase

    UniProtKB/Swiss-Prot: ACYP2_HUMAN, P14621
    Similarity: Belongs to the acylphosphatase family
    Similarity: Contains 1 acylphosphatase-like domain


    Find genes that share domains with ACYP2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ACYP2_HUMAN, P14621
    Function: Its physiological role is not yet clear
    Catalytic activity: An acylphosphate + H(2)O = a carboxylate + phosphate

         Enzyme Number (IUBMB): EC 3.6.1.71 2

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003998acylphosphatase activity IBA--
         
    Find genes that share ontologies with ACYP2           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Acyp2 (no phenotypes)

    Find genes that share phenotypes with ACYP2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ACYP2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ACYP2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ACYP2

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    1 qRT-PCR Assays for microRNA that regulate ACYP2:
    hsa-miR-205*
    SwitchGear 3'UTR luciferase reporter plasmidACYP2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ACYP2
    Predesigned siRNA for gene silencing in human, mouse, rat ACYP2

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    GenScript: all cDNA clones in your preferred vector: ACYP2 (NM_138448)
    Sino Biological Human cDNA Clone for ACYP2
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACYP2

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    endoplasmic reticulum2
    mitochondrion2
    nucleus1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--

    Find genes that share ontologies with ACYP2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ACYP2 About    
    See pathways by source

    SuperPathContained pathways About
    1Purine metabolism (KEGG)
    ATP ITP metabolism0.31
    2Pyruvate metabolism
    Pyruvate metabolism


    Find genes that share SuperPaths with ACYP2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for ACYP2
        ATP/ITP metabolism



    1 Kegg Pathway  (Kegg details for ACYP2):
        Pyruvate metabolism

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ACYP2
    Interactions:

        Search GeneGlobe Interaction Network for ACYP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for ACYP2 (P146213 ENSP000003781614) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GABARAPL1Q9H0R83I2D: score=1 
    ACSS2ENSP000003538044STRING: ENSP00000353804
    ALDH9A1ENSP000003468274STRING: ENSP00000346827
    ACOT12ENSP000003032464STRING: ENSP00000303246
    ACSS1ENSP000003169244STRING: ENSP00000316924
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006796phosphate-containing compound metabolic process TAS8268218

    Find genes that share ontologies with ACYP2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ACYP2

    Selected HMDB Compounds for ACYP2 (see all 13)    About this table
    CompoundSynonyms CAS #PubMed Ids
    Acetic acidAcetate (see all 12)64-19-7--
    Arachidic acidArachate (see all 10)506-30-9--
    Arachidonic acid5,8,11,14-Eicosatetraenoic acid (see all 16)506-32-1--
    Benzoic acidBenzenecarboxylate (see all 22)65-85-0--
    Heptadecanoic acidHeptadecanoate (see all 16)506-12-7--
    Heptadecanoyl CoAHeptadecanoyl coenzyme A (see all 19)3546-17-6--
    Myristic acid1-Tridecanecarboxylate (see all 15)544-63-8--
    Palmitic acidHexaectylic acid (see all 45)57-10-3--
    Pentadecanoic acidPentadecanoate (see all 8)1002-84-2--
    PhosphateNFB Orthophosphate (see all 13)14265-44-2--

    1 DrugBank Compound for ACYP2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Formic AcidAminic acid (see all 5)64-18-6target--10592235

    5 Novoseek inferred chemical compound relationships for ACYP2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    trifluoroethanol 56.8 1 14741220 (1)
    urea 43 2 9477974 (1), 10400629 (1)
    lysine 21.7 1 9740373 (1)
    alanine 11.5 2 10400629 (1)
    calcium 0 3 9352082 (2), 1319152 (1)



    Find genes that share compounds with ACYP2           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ACYP2 gene: 
    NM_138448.3  

    Unigene Cluster for ACYP2:

    Acylphosphatase 2, muscle type
    Hs.516173  [show with all ESTs]
    Unigene Representative Sequence: BX647332
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000606082 ENST00000458030 ENST00000607452 ENST00000422521 ENST00000406041
    ENST00000303536 ENST00000394666(uc002rxq.4) ENST00000494922 ENST00000606865

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate ACYP2:
    hsa-miR-205*
    SwitchGear 3'UTR luciferase reporter plasmidACYP2 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK307096.1 BC012290.1 BX647332.1 

    13 DOTS entries:

    DT.315403  DT.97843493  DT.121015667  DT.95098573  DT.95266061  DT.95154364  DT.92445534  DT.101966008 
    DT.92445546  DT.92445548  DT.92445552  DT.100778111  DT.95144143 

    Selected AceView cDNA sequences (see all 142):

    BM926245 NM_138448 AA905921 BM980898 BG204333 AI362804 CD679178 BE698700 
    BU538727 BU857820 BI768667 AA405029 AA284358 BC012290 BM460084 BU726627 
    BE698517 BG191115 BM976314 BG211650 AI367992 BG200228 BG181591 BG193068 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ACYP2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c
    SP1:        -     -     -     -     -           -                     
    SP2:                    -     -     -     -     -                     
    SP3:                                -     -                           
    SP4:                                      -     -                     
    SP5:        -     -     -     -     -     -     -                     


    ECgene alternative splicing isoforms for ACYP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ACYP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAATCTTTAA
    ACYP2 Expression
    About this image

    ACYP2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ACYP2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.516173
        Custom PCR Arrays for ACYP2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACYP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ACYP2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Acyp21 , 5 acylphosphatase 2, muscle type1, 5 82.65(n)1
    83.67(a)1
      11 (18.16 cM)5
    755721  NM_029344.31  NP_083620.11 
     305059915 
    chicken
    (Gallus gallus)
    Aves ACYP21 acylphosphatase 2, muscle type 83.33(n)
    89.36(a)
      421217  NM_001167762.1  NP_001161234.1 
    lizard
    (Anolis carolinensis)
    Reptilia ACYP26
    acylphosphatase 2, muscle type
    69(a)
    1 ↔ 1
    1(263217842-263297545)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia acyp21 acylphosphatase 2, muscle type 75.27(n)
    83.87(a)
      548511  NM_001015794.1  NP_001015794.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CABZ01090073.16
    Acylphosphatase
    46(a)
    1 ↔ 1
    11(44256202-44258256) ENSDARG00000086271
    fruit fly
    (Drosophila melanogaster)
    Insecta CG140221 CG14022 51.25(n)
    44.09(a)
      33763  NM_135078.2  NP_608922.1 


    ENSEMBL Gene Tree for ACYP2 (if available)
    TreeFam Gene Tree for ACYP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ACYP2 gene
    ACYP12  
    1 SIMAP similar gene for ACYP2 using alignment to 11 protein entries:     ACYP2_HUMAN (see all proteins):
    ACYP1

    Find genes that share paralogs with ACYP2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ACYP2 (see all 4390)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs75654531,2
    C--54340468(+) gcctcC/Gtgggc 1 -- us2k14Minor allele frequency- G:0.25WA NA EA 360
    rs728007461,2
    C,F--54340680(+) GCAGGC/ACAAGA 1 -- us2k12Minor allele frequency- A:0.14NA 122
    rs1842259011,2
    --54340813(+) CCACTC/TGCAGA 1 -- us2k10--------
    rs1423520611,2
    --54340829(+) CTGAGC/TGGGAT 1 -- us2k10--------
    rs1113900601,2
    C,F--54340830(+) TGAGCG/AGGATA 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs3697941361,2
    C--54340876(+) TAGAGC/G/TGACCC 1 -- us2k10--------
    rs1887304881,2
    --54340885(+) CCCAAC/GAGAAG 1 -- us2k10--------
    rs1920118221,2
    --54341002(+) CCTTAA/GGTTCT 1 -- us2k10--------
    rs1833340461,2
    --54341091(+) GAGTTA/GAGTTA 1 -- us2k10--------
    rs1870858741,2
    --54341097(+) AGTTAC/GGAGGT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ACYP2 (54197975 - 54447975 bp, first 250kb of ACYP2)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ACYP2 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2720078CNV Deletion23290073
    esv2664152CNV Deletion23128226
    esv2318898CNV Deletion18987734
    esv2720079CNV Deletion23290073
    esv2665732CNV Deletion23128226
    nsv507013CNV Insertion20534489
    dgv4143n71CNV Loss21882294
    esv27584CNV Loss19812545
    esv23028CNV Loss19812545
    nsv525086CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 102595    OMIM disorders: --


    Find genes that share disorders with ACYP2           About GenesLikeMe

    Genetic Association Database (GAD): ACYP2
    Human Genome Epidemiology (HuGE) Navigator: ACYP2 (5 documents)

    Export disorders for ACYP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ACYP2 gene, integrated from 10 sources (see all 48):
    (articles sorted by number of sources associating them with ACYP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease. (PubMed id 21658281)1, 4 Aouizerat B.E....Tseng Z.H. (BMC Cardiovasc Disord 2011)
    2. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (Am. J. Hypertens. 2010)
    3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    4. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2010)
    5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    6. Replication of a genome-wide case-control study of esophageal squamous cell carcinoma. (PubMed id 18649358)1, 4 Ng D....Taylor P.R. (Int. J. Cancer 2008)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Cloning and expression of the cDNA coding for the erythrocyte isoenzyme of human acylphosphatase. (PubMed id 7796909)1, 2 Fiaschi T....Ramponi G. (FEBS Lett. 1995)
    9. Chemical synthesis and expression of a gene coding for human muscle acylphosphatase. (PubMed id 8268218)1, 3 Modesti A....Ramponi G. (Biochim. Biophys. Acta 1993)
    10. Human skeletal muscle acylphosphatase: the primary structure. (PubMed id 6100723)1, 2 Manao G.... Ramponi G. (Mol. Biol. Med. 1984)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 98 HGNC: 180 AceView: ACYP2 Ensembl:ENSG00000170634 euGenes: HUgn98
    ECgene: ACYP2 Kegg: 98 H-InvDB: ACYP2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ACYP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ACYP2 gene:
    Search GeneIP for patents involving ACYP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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