Aliases for ACYP2 Gene
External Ids for ACYP2 Gene
Previous GeneCards Identifiers for ACYP2 Gene
Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
GeneCards Summary for ACYP2 Gene
ACYP2 (Acylphosphatase 2) is a Protein Coding gene. Diseases associated with ACYP2 include Long Qt Syndrome 1. Among its related pathways are Pyrimidine metabolism (KEGG) and Pyruvate metabolism. GO annotations related to this gene include acylphosphatase activity. An important paralog of this gene is ACYP1.
UniProtKB/Swiss-Prot for ACYP2 Gene
Its physiological role is not yet clear.