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ACVR2A Gene

protein-coding   GIFtS: 62

GC02P148319
activin A receptor, type IIA
(Previous names: activin A receptor, type II )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: ACVR2)
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases
ACTR-IIA 3
ACTRII 1, 2
ACTRIIA 3
ACVR2 2, 3, 5
EC 2.7.11.30 3
Descriptions
Activin receptor type IIA 3
activin A receptor, type II 1
activin A receptor, type IIA 2
External Ids
HGNC: 1731
Entrez Gene: 922
UniProtKB: P270373
Ensembl: ENSG000001219897
Search outside databases for aliases for ACVR2A gene

Previous GC identifer: GC02P148437

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for ACVR2A:
This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation
factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally
related signaling proteins. Activins signal through a heteromeric complex of receptor serine
kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These
receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with
cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted
serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors
are required for binding ligands and for expression of type I receptors. Type I and II receptors
form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by
type II receptors. Type II receptors are considered to be constitutively active kinases. [provided
by RefSeq]

UniProtKB/Swiss-Prot: AVR2A_HUMAN, P27037
Function: On ligand binding, forms a receptor complex consisting of two type II and two type I
transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I
receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.
Receptor for activin A, activin B and inhibin A

Gene Wiki entry for ACVR2A

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ACVR2A gene  

Entrez Gene cytogenetic band: 2q22.3   Ensembl cytogenetic band:  2q22.3   HGNC cytogenetic band: 2q22.2-q23.3

ACVR2A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P148319:     (about GC identifiers)

Start:
148,318,655 bp from pter
End:
148,404,863 bp from pter
Size:
86,209 bases
Orientation:
plus strand
RefSeq DNA sequence:
NC_000002.10  NT_022135.15  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: AVR2A_HUMAN, P27037 (See protein sequence)
Recommended Name: Activin receptor type-2A precursor  
Size: 513 amino acids; 57848 Da
Cofactor: Magnesium or manganese (By similarity)
Subunit: Interacts with AIP1. Part of a complex consisting of AIP1, ACVR2A, ACVR1B and SMAD3 (By
similarity)
Subcellular location: Membrane; Single-pass type I membrane protein
Secondary accessions: Q53TH4 Q6NWV2 Q92474

REFSEQ proteins: NP_001607.1  

ENSEMBL proteins: 
ENSP00000385568 ENSP00000241416 ENSP00000384338 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
Browse Purified and Recombinant Proteins at Millipore
Sigma-Aldrich Proteins for ACVR2A  
R&D Systems Recombinant & Natural Proteins for ACVR2A (Activin RIIA)
Browse recombinant and purified proteins available from Enzo Life Sciences
Recombinant Proteins from Abcam (Activin Receptor Type IIA)
Human Recombinant Proteins from Abnova (ACVR2A)
                Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005737 cytoplasm IDA14738881
GO:0005886 plasma membrane EXP17356069
GO:0005887 integral to plasma membrane TAS1314589
GO:0034673 inhibin-betaglycan-ActRII complex IDA10746731
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Antibodies for ACVR2A: 
Browse Antibodies Central at Invitrogen
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Sigma-Aldrich Antibodies for ACVR2A
R&D Systems Antibodies for ACVR2A (Activin RIIA)
Antibodies from Abcam (Activin Receptor Type IIA), each with their AbpromiseSM
Monoclonal and Polyclonal Antibodies from Abnova (ACVR2A)
Novus Biologicals Antibodies for ACVR2A

Assays for ACVR2A: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

5/7 InterPro domains/families (see all 7 ):
 IPR015768 Activin_II_recpt_C
 IPR017441 Protein_kinase_ATP_BS
 IPR017442 Se/Thr_pkinase-rel
 IPR008271 Ser_thr_pkin_AS
 IPR000472 Activin_rcpt


   GeneDecks  ACVR2A for the domains selected above  
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Graphical View of Domain Structure for InterPro Entry P27037

ProtoNet protein and cluster: P27037

2 Blocks protein families:
IPB000333 Activin type II receptor signature
IPB000472 Domain in TGF-beta receptor/activin receptor


UniProtKB/Swiss-Prot: AVR2A_HUMAN, P27037
Similarity: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB
receptor subfamily
Similarity: Contains 1 protein kinase domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib.
RNA:
Invitrogen RNAi Products for gene knock-down (ACVR2A)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (ACVR2A)
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001616

              Applied Biosystems Silencer® siRNAs for ACVR2A

              Sigma-Aldrich siRNA and siRNA Panels for ACVR2A  
                     Sigma-Aldrich shRNA Panels and shRNA for ACVR2A  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Invitrogen Clones for ACVR2A
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001616
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001616
                                 untagged cDNA clone in CMV expression vector: NM_001616 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_001616

UniProtKB/Swiss-Prot: AVR2A_HUMAN, P27037
Function: On ligand binding, forms a receptor complex consisting of two type II and two type I
transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I
receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.
Receptor for activin A, activin B and inhibin A
Catalytic activity: ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Enzyme Number (IUBMB): EC 2.7.11.30 

13 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Acvr2a):

craniofacialdigestive/alimentaryembryogenesisendocrine/exocrine gland
growth/sizehomeostasis/metabolismlethality-prenatal/perinatalnervous systemreproductive system
respiratory systemskeletonvision/eye

5/11 Gene Ontology (GO) molecular function terms (links to tree view) (see all 11 ):

GO IDQualified GO termEvidencePubMed IDs
GO:0000166 nucleotide binding IEA--
GO:0000287 magnesium ion binding IEA--
GO:0005524 ATP binding IEA--
GO:0015026 coreceptor activity IDA10746731
GO:0016740 transferase activity IEA--
About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section


2 Millipore Pathways for ACVR2A
 Development Role of Activin A in cell differentiation and proliferation
 Signal transduction Activin A signaling regulation

   GeneDecks  ACVR2A for the pathways selected above  
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5/6 Sigma-Aldrich "Your Favorite Gene" Pathways for  ACVR2A  (Your Favorite Gene powered by Ingenuity) (see all 6
 Inositol Phosphate Metabolism
 Nicotinate and Nicotinamide Metabolism
 Wnt/&beta
 TGF-&beta
 Factors Promoting Cardiogenesis in Vertebrates

   GeneDecks  ACVR2A for the pathways selected above  
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2 Kegg Pathways  (Kegg details for ACVR2A):
 hsa04060 Cytokine-cytokine receptor interaction
 hsa04350 TGF-beta signaling pathway

   GeneDecks  ACVR2A for the pathways selected above  
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 Gene Network CentralTM Interacting Genes and Proteins Network for  ACVR2A 


5/44 Interacting proteins for ACVR2A (P270372 ENSP000002414163) via UniProtKB, MINT, and/or STRING (see all 44 )
InteractantInteraction Details
GeneCardExternal ID(s)
BMP7ENSP000003603403STRING (score=.999)
INHBAENSP000002422083STRING (score=.999)
BMP2ENSP000003681043STRING (score=.998)
INHBEENSP000002666463STRING (score=.998)
INHBBENSP000002952283STRING (score=.997)
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5/16 Gene Ontology (GO) biological process terms (links to tree view) (see all 16 ):

GO IDQualified GO termEvidencePubMed IDs
GO:0001702 gastrulation with mouth forming second IEA--
GO:0006468 protein amino acid phosphorylation IEA--
GO:0007283 spermatogenesis IEA--
GO:0007368 determination of left/right symmetry IEA--
GO:0007498 mesoderm development IEA--
About this table
(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ACVR2A
2 Novoseek chemical compound relationships for ACVR2A gene
Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
threonine 64.05 2 10652306 (1), 12665502 (1)
ribonucleic acid 39.09 1 7962340 (1)
About this table


(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib.
RNA:
Invitrogen RNAi Products for gene knock-down (ACVR2A)
Browse for Gene Knock-down Tools from Millipore
Abnova Chimera RNAi Products for Gene knock-down (ACVR2A)
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001616

              Sigma-Aldrich siRNA and siRNA Panels for ACVR2A  
                     Sigma-Aldrich shRNA Panels and shRNA for ACVR2A  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_001616  

REFSEQ mRNAs for ACVR2A gene: 

NM_001616.3   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_001616  

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001616
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001616
                                 untagged cDNA clone in CMV expression vector: NM_001616 

Additional cDNA sequence: 

AK301629.1 AK314124.1 BC067416.1 BC067417.1 BC067418.1 BC069707.1 D31770.1 M93415.1 
X62381.1 X63128.1 

10 DOTS entries:

DT.91752473  DT.91735091  DT.91866420  DT.116024  DT.121032318  DT.121032222  DT.429751  DT.435266 
DT.97812347  DT.99958247 

24/79 AceView cDNA sequences (see all 79 ):

BX281966 CB142176 BG616903 BE856769 AL047127 BM503220 BC069707 BX645435 
X62381 BQ008322 AI554024 BC067418 BC067417 X63128 CB144602 BQ720564 
AA331510 AI433335 BX492395 CF271903 AW044576 AI829731 NM_001616 AA952974 

highest scoring ESTs for ACVR2A:

D31770 AA593728 AA918237 AA952974 AI335550 AI376182 AI433335 AI433467 AI433757 AI554024 

Unigene Cluster for ACVR2A:

Activin A receptor, type IIA
Hs.470174  [show with all ESTs]
Unigene Representative Sequence: NM_001616


GeneLoc Exon Structure

3 Ensembl transcripts including schematic representations:
ENST00000402410  ENST00000241416  ENST00000404590  
(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ACVR2A expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for ACVR2A

1 / 2 / 3

7 probe-sets matching ACVR2A gene


Affymetrix
probe-set
Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

53468_at2, 3 U95-B 1 1.00 1.00 0.92 0.98 AI149508 0.80 0.80 0.80 1

35162_s_at2, 3 U95-A 1 1.00 1.00 0.93 0.85 D31770 1.00 0.90 0.95 1
62358_at2, 3 U95-C 1 0.94 1.00 0.78 1.18 AI433757 0.80 1.00 0.91 1

205327_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_001616 0.60 1.00 0.82 1

228416_at2, 3 U133-B 1 1.00 1.00 -- -- AI149508 0.80 0.80 0.80 1

205327_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

228416_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
GeneDecks  ACVR2A for binary patterns associated with the probe-sets selected above  
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About this table    
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.470174

Expression variation in blood from EXPOLDB for ACVR2A

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section


Orthologs for ACVR2A gene from 5/10 species (see all 10 )
Organism Gene Locus Description Human
Similarity
NCBI accessions
dog
(Canis familiaris)
ACVR2A1   -- activin A receptor, type IIA 95.26(n)
98.83(a)
476140  XM_852370.1  XP_857463.1 
cow
(Bos taurus)
ACVR2A1   -- activin A receptor, type IIA 95.13(n)
98.64(a)
281598  NM_174227.2  NP_776652.1 
rat
(Rattus norvegicus)
Acvr2a1   -- activin A receptor, type IIA 94.02(n)
99.42(a)
29263  NM_031571.1  NP_113759.1 
mouse
(Mus musculus)
Acvr2a1, 5 2 (30.00 cM)5
activin receptor IIA1, 5 94.48(n)1
99.22(a)1
114801  NM_007396.31  NP_031422.21 
 AK0412465  AK1414355  (see all 17)
chicken
(Gallus gallus)
ACVR2A1   -- activin A receptor, type IIA 83.43(n)
92.59(a)
396324  NM_205367.1  NP_990698.1 
About this table        Species with no ortholog for ACVR2A

ENSEMBL Gene Tree for ACVR2A
(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Paralogs for ACVR2A gene
TGFBR22  ACVR2B2  

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section


10/281 NCBI SNPs in ACVR2A are shown (see all 281 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 110)
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr 2 posSequenceRecsAA
Chg
TypeMoreRecsAllele
freq
PopTotal
sample
More
------------
rs14249541,2
A,C,F,H,O148317264(+) ACAGAG/AACTGT 1 -- ng515Minor allele frequency- A:0.32EA NA EU WA 292
rs176926481,2
C,F,H148404201(+) TGAAAA/CTACAA 1 -- ut3112Minor allele frequency- C:0.11NA EU EA WA 1054
--
rs126917691,2
A,C148318008(+) TCGGTA/CTCAGA 1 -- ng510--------
rs134300861,2
F,H148403531(+) AAAAAA/TTTTTT 1 -- ut311Minor allele frequency- T:0.45EU 120
--
rs124746531,2
A148319013(+) TTTTTC/TCTTTT 1 -- ng51 trp30--------
--
rs120531131,2
A148318130(+) CCCTTC/TGGGTG 1 -- ng510--------
rs132241,2
C148319154(+) ATCTAG/TCGAGA 1 -- ut511Minor allele frequency- T:0.00MN 184
--
rs120527361,2
A148318147(+) CCAGAC/GAGGCC 1 -- ng510--------
rs349175711,2
C148391423(+) ACCAGT/GGTTGA 1 R/S mis14Minor allele frequency- G:0.00EU EA WA 420
rs10470811,2
H148404773(+) ACCCCA/CCCTTG 1 -- ut315Minor allele frequency- C:0.02MN EU EA WA 602
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HapMap Linkage Disequilibrium images for ACVR2A (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 102581

10 Novoseek disease relationships for ACVR2A gene

Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
microsatellite instability 41.80 1 12615714 (1)
colon cancer 34.67 12 15520171 (2), 14988818 (2), 16380996 (1), 17258738 (1) (see all 5)
preeclampsia 26.67 2 19126782 (1)
pheochromocytoma 9.28 1 10810314 (1)
pancreatic cancer 2.88 3 12615714 (2), 9714055 (1)
tumors 2.06 20 14988818 (3), 16380996 (3), 8636304 (2), 16337854 (2) (see all 8)
cancer 0.00 2 14988818 (1), 9714055 (1)
carcinoma 0.00 3 18077314 (1), 17121532 (1), 17478078 (1)
ovarian cancer 0.00 1 11306176 (1)
colorectal cancer 0.00 3 14988818 (2), 17609433 (1)
About this table

Genetic Association Database: ACVR2A
Human Genome Epidemiology Navigator: ACVR2A (3 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

  --

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
About This Section

10/140 PubMed articles for ACVR2A gene (see all 140 ):
(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)
(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 92 HGNC: 173 AceView: ACVR2 Ensembl:ENSG00000121989 euGenes: HUgn92
ECgene: ACVR2A H-InvDB: ACVR2A
(According to HUGE)
About This Section

  --
(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

NameDescription
ATLAS Chromosomes in Cancer entry for ACVR2A Genetics and Cytogenetics in Oncology and Haematology
CGP resequencing studieshttp://www.sanger.ac.uk/perl/genetics/CGP/cgp_viewer?action=gene&ln=ACVR2
(Available from WIS Yeda, Salk, Tufts)
About This Section

  --
(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for ACVR2A:
 TaqMan ® Gene Expression Assays
 TaqMan ® Genotyping Assays
  Free SNP selection tool



  Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
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 Predesigned and custom siRNAs for ACVR2A Antibodies for ACVR2A
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 Lentivirus-delivered shRNAs for ACVR2A Browse small molecules at Sigma-Aldrich
 "Your Favorite Gene" Pathwaysfeedback


  
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 Recombinant & Natural Proteins  

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 Recombinant Proteins
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 Antibodies (Activin Receptor Type IIA)
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 Search Tocris compounds for ACVR2A




 Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
 Antibodies for ACVR2A

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