V3 here soon-try beta now
Gene Search (GeneCards Home) | GeneCards Guide | User Feedback | Terms of Use | Notice about third-party sites
 

ACVR1C Gene

protein-coding   GIFtS: 53

GC02M158097
activin A receptor, type IC
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases
ACTR-IC 3
ACVRLK7 1, 2
ALK-7 3
ALK7 1, 2, 3, 5
EC 2.7.11.30 3
Descriptions
Activin receptor-like kinase 7 2, 3
activin A receptor, type IC 2
External Ids
HGNC: 181231
Entrez Gene: 1303992
UniProtKB: Q8NER53
Ensembl: ENSG000001236127
Search outside databases for aliases for ACVR1C gene

Previous GC identifers: GC02M158352 GC02M158592 GC02M158593 GC02M158214

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ACVR1C:
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon
ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then
translocate to the nucleus and interact directly with DNA or in complex with other transcription
factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM]

UniProtKB/Swiss-Prot: ACV1C_HUMAN, Q8NER5
Function: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The
receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type
II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and
activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and
NODAL. Plays a role in cell differentiation, growth arrest and apoptosis

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ACVR1C gene  

Entrez Gene cytogenetic band: 2q24.1   Ensembl cytogenetic band:  2q24.1   HGNC cytogenetic band: 2q24.2

ACVR1C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M158097:     (about GC identifiers)

Start:
158,097,150 bp from pter
End:
158,193,645 bp from pter
Size:
96,496 bases
Orientation:
minus strand
RefSeq DNA sequence:
NC_000002.10  NT_005403.16  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ACV1C_HUMAN, Q8NER5 (See protein sequence)
Recommended Name: Activin receptor type-1C precursor  
Size: 493 amino acids; 54871 Da
Cofactor: Magnesium or manganese
Subunit: Binds the type 2 receptor protein ACVR2A (By similarity)
Subcellular location: Membrane; Single-pass type I membrane protein
Secondary accessions: Q4ZFZ8 Q86UL1 Q86UL2 Q8TBG2
Alternative splicing: 4 isoforms:  Q8NER5-1   Q8NER5-2   Q8NER5-3   Q8NER5-4   

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins (4 alternative transcripts): 
    NP_001104501.1  NP_001104502.1  NP_001104503.1  NP_660302.2  


    ENSEMBL proteins: 
    ENSP00000243349 ENSP00000335178 ENSP00000335139 ENSP00000387168 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Activin A Receptor Type IC)
    Human Recombinant Proteins from Abnova (ACVR1C)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016020 membrane IEA--
    GO:0016021 integral to membrane IEA--
    GO:0048179 activin receptor complex IDA15531507
    About this table

    Antibodies for ACVR1C: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for ACVR1C
    R&D Systems Antibodies for ACVR1C (ALK-7)
    Antibodies from Abcam (Activin A Receptor Type IC), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (ACVR1C)
    Novus Biologicals Antibodies for ACVR1C

    Assays for ACVR1C: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    5/6 InterPro domains/families (see all 6 ):
     IPR017441 Protein_kinase_ATP_BS
     IPR017442 Se/Thr_pkinase-rel
     IPR008271 Ser_thr_pkin_AS
     IPR003605 TGF_beta_rcpt_GS
     IPR000472 Activin_rcpt


       GeneDecks  ACVR1C for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q8NER5

    ProtoNet protein and cluster: Q8NER5

    1 Blocks protein family: IPB000472 Domain in TGF-beta receptor/activin receptor

    UniProtKB/Swiss-Prot: ACV1C_HUMAN, Q8NER5
    Similarity: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB
    receptor subfamily
    Similarity: Contains 1 GS domain
    Similarity: Contains 1 protein kinase domain

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ACVR1C)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ACVR1C)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_145259

                  Applied Biosystems Silencer® siRNAs for ACVR1C

                  Sigma-Aldrich siRNA and siRNA Panels for ACVR1C  
                         Sigma-Aldrich shRNA Panels and shRNA for ACVR1C  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for ACVR1C
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_001111031
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_001111031
                                     untagged cDNA clones in CMV expression vector (see all 6): NM_001111031 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_145259

    UniProtKB/Swiss-Prot: ACV1C_HUMAN, Q8NER5
    Function: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The
    receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type
    II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and
    activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and
    NODAL. Plays a role in cell differentiation, growth arrest and apoptosis
    Catalytic activity: ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
    Enzyme Number (IUBMB): EC 2.7.11.30 

    2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Acvr1c):

    life span-post-weaning/agingnormal

    5/10 Gene Ontology (GO) molecular function terms (links to tree view) (see all 10 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166 nucleotide binding IEA--
    GO:0000287 magnesium ion binding IEA--
    GO:0004674 protein serine/threonine kinase activity IEA--
    GO:0004872 receptor activity IEA--
    GO:0005024 transforming growth factor beta receptor activity IEA--
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    4 Sigma-Aldrich "Your Favorite Gene" Pathways for  ACVR1C  (Your Favorite Gene powered by Ingenuity) 
     TGF-&beta
     PPAR&alpha
     Wnt/&beta
     Factors Promoting Cardiogenesis in Vertebrates

       GeneDecks  ACVR1C for the pathways selected above  
    About GeneDecksing

    5/7 Kegg Pathways  (Kegg details for ACVR1C) (see all 7 ):
     hsa04010 MAPK signaling pathway
     hsa04350 TGF-beta signaling pathway
     hsa04520 Adherens junction
     hsa05200 Pathways in cancer
     hsa05210 Colorectal cancer

       GeneDecks  ACVR1C for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  ACVR1C 


    5/31 Interacting proteins for ACVR1C (ENSP000002433493) via UniProtKB, MINT, and/or STRING (see all 31 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD2ENSP000002621603STRING (score=.985)
    SMAD3ENSP000003329733STRING (score=.985)
    INHBEENSP000002666463STRING (score=.97)
    GDF11ENSP000002578683STRING (score=.943)
    TGFB1ENSP000002219303STRING (score=.941)
    About this table

    3 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468 protein amino acid phosphorylation IC12063393
    GO:0030154 cell differentiation IDA15531507
    GO:0042981 regulation of apoptosis IDA15531507
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for ACVR1C
    1 Novoseek chemical compound relationship for ACVR1C gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    threonine 63.23 3 12063393 (1), 12606401 (1), 15196700 (1)
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ACVR1C)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ACVR1C)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_145259

                  Sigma-Aldrich siRNA and siRNA Panels for ACVR1C  
                         Sigma-Aldrich shRNA Panels and shRNA for ACVR1C  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001111031  NM_001111032  NM_001111033  NM_145259  

    REFSEQ mRNAs for ACVR1C gene (4 alternative transcripts): 

    NM_001111031.1   NM_001111032.1   NM_001111033.1   NM_145259.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001111031  NM_001111032  NM_001111033  NM_145259  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_001111031
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_001111031
                                     untagged cDNA clones in CMV expression vector (see all 6): NM_001111031 

    Additional cDNA sequence: 

    AF525679.1 AF525680.1 AF525681.1 AY127050.1 BC022530.1 BC030101.2 

    7 DOTS entries:

    DT.91745490  DT.100748869  DT.99928652  DT.100748870  DT.95179535  DT.75144520  DT.95303326 

    24/32 AceView cDNA sequences (see all 32 ):

    BQ082584 CD637605 BP382222 CD637278 AF525679 CD637599 CD637609 NM_145259 
    CD637607 AF525681 BU167095 BC022530 CD637597 AY127050 BQ711640 CD637601 
    CD637603 CD637611 AF525680 CD637280 CD637613 CD637592 BU161536 CD637590 

    highest scoring ESTs for ACVR1C:

    AF525680 AF525681 AY127050 BC022530 BG036887 BG716697 BI601014 BF966584 BQ082584 BU161536 

    Unigene Cluster for ACVR1C:

    Activin A receptor, type IC
    Hs.562901  [show with all ESTs]
    Unigene Representative Sequence: NM_145259


    GeneLoc Exon Structure

    4 Ensembl transcripts including schematic representations:
    ENST00000243349  ENST00000335450  ENST00000348328  ENST00000409680  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ACVR1C expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ACVR1C

    1 / 2

    2 probe-sets matching ACVR1C gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    1552519_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    1563182_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene cluster: Hs.562901

    UniProtKB/Swiss-Prot: ACV1C_HUMAN, Q8NER5
    Tissue specificity: Present in pancreas, heart, colon, small intestine, ovary and the hippocampus,
    medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all
    expressed in the placenta throughout pregnancy

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for ACVR1C gene from 5/6 species (see all 6 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    ACVR1C1   -- activin A receptor, type IC 86.43(n)
    90.08(a)
    488361  XM_545483.2  XP_545483.2 
    chimpanzee
    (Pan troglodytes)
    ACVR1C1   -- activin A receptor, type IC 99.59(n)
    99.39(a)
    470564  XM_525945.2  XP_525945.2 
    cow
    (Bos taurus)
    ACVR1C1   -- activin A receptor, type IC 93.6(n)
    97.65(a)
    536380  XM_616508.3  XP_616508.3 
    rat
    (Rattus norvegicus)
    Acvr1c1   -- activin A receptor, type IC 86(n)
    92.7(a)
    245921  NM_139090.1  NP_620790.1 
    mouse
    (Mus musculus)
    Acvr1c1, 5 25
    activin A receptor, type IC1, 5 87.01(n)1
    95.91(a)1
    2692751  NM_001033369.21  NP_001028541.11 
     AI6438725  AK0490895  (see all 10)
    About this table        Species with no ortholog for ACVR1C

    ENSEMBL Gene Tree for ACVR1C
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for ACVR1C gene
    TGFBR12  ACVR1B2  

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/282 NCBI SNPs in ACVR1C are shown (see all 282 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 81)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 2 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs101672071,2
    A,C,F,H158094367(+) ATCTAA/CACAAA 4 -- ut314Minor allele frequency- C:0.10EU EA WA 418
    rs67346301,2
    A,C,F,H158093044(+) CCTAAA/GGCACT 4 -- ut317Minor allele frequency- G:0.13EU EA WA NA 558
    rs45569331,2
    A,C,F,H158152135(+) CAGGTG/AAAGTT 4 F/F syn1 ut519Minor allele frequency- A:0.42EU EA WA NA 848
    rs75944801,2
    C,F,H158098714(+) AGATAT/CAGTCT 4 V/I mis1 ese38Minor allele frequency- C:0.16EU EA WA 838
    rs46642291,2
    C,F,H158095184(+) AAAGAT/CAACCC 4 -- ut317Minor allele frequency- C:0.10EU EA WA NA 558
    rs129938001,2
    C,F,H158097025(+) TGGGAC/TAGTAA 4 -- ut318Minor allele frequency- T:0.24EU EA WA 836
    rs355009791,2
    C158107501(+) GTCGAT/CAGTGT 4 V/I mis14Minor allele frequency- C:0.00EU EA WA 420
    rs67515951,2
    H158097764(+) TATGAG/TAAAAA 4 -- ut314Minor allele frequency- T:0.00EU EA WA 418
    --
    rs171804181,2
    F158162284(+) CTCCCG/ACGGGG 2 -- ut51 int13Minor allele frequency- A:0.01NA 142
    rs347429241,2
    C158115049(+) TTCCCC/GACACC 3 G/R mis14Minor allele frequency- G:0.00EU EA WA 420
    About this table

    HapMap Linkage Disequilibrium images for ACVR1C (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 608981

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/20 PubMed articles for ACVR1C gene (see all 20 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 130399 HGNC: 18123 AceView: ACVR1C Ensembl:ENSG00000123612 euGenes: HUgn130399
    ECgene: ACVR1C H-InvDB: ACVR1C
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    NameDescription
    ATLAS Chromosomes in Cancer entry for ACVR1C Genetics and Cytogenetics in Oncology and Haematology
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ACVR1C:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ACVR1C-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for ACVR1C Antibodies for ACVR1C
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for ACVR1C Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (ACVR1C)
     Antibodies (ACVR1C)
     Chimera RNAi (ACVR1C)
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (Activin A Receptor Type IC)
     Antibodies (Activin A Receptor Type IC)
     Search OriGene for ACVR1C
     Search Tocris compounds for ACVR1C




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for ACVR1C

    GeneCards Homepage    -    Last full update: 1 Jul 2009        Incremental update: 13 Oct 2009

    Random Gene From GIFtS : about GIFtS

    Gene Index:   3   5   A   B   C   D   E   F   G   H   I   J   K   L   M   N   O   P   Q   R   S   T   U   V   W   X   Y   Z

    Developed at the Crown Human Genome Center & Weizmann Institute of Science



    The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
    ACVR1C Gene at Home site.
    Version 2.41.1
    server5.xennexinc.com