Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ACTRT2 Gene

protein-coding   GIFtS: 45
GCID: GC01P002962

actin-related protein T2
 Explore 1 disease affiliated with
ACTRT2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ACTRT2    

Aliases
for ACTRT2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Actin-Related Protein T21 2     FLJ254241
ARPM21 2 3 5     HARPM22
Arp-T21 2     Actin-Related Protein HArpM22
Actin-Related Protein M22 3     ARP-T23
ARPT22 5     

External Ids:    HGNC: 240261   Entrez Gene: 1406252   Ensembl: ENSG000001697177   OMIM: 6085355   UniProtKB: Q8TDY33   

Export aliases for ACTRT2 gene to outside databases

Previous GC identifer: GC01P002233


Summaries
for ACTRT2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ACTRT2:
The protein encoded by this intronless gene belongs to the actin family. Studies have shown that this protein may be
involved in cytoskeletal organization similar to other cytoplasmic actin-related protein (ARP) subfamily members.
Antibody raised against the human protein has been used to detect the protein by immunoblotting and immunofluorescence
microscopy, demonstrating its specific synthesis in the testis, late in spermatid differentiation, and its
localization in the calyx. (provided by RefSeq, Jul 2008)




Genomic Views
for ACTRT2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_004350.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ACTRT2 gene promoter:
         Sox5   p300   Nkx2-2   Olf-1   IRF-1   AP-2gamma   Roaz   PPAR-alpha   SRY   Sox9   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ACTRT2 promoter sequence
   Search SABiosciences Chromatin IP Primers for ACTRT2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACTRT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.32   Ensembl cytogenetic band:  1p36.32   HGNC cytogenetic band: 1p36.3

ACTRT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACTRT2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P002962:  view genomic region     (about GC identifiers)

Start:
 2,938,046 bp from pter      End:
 2,939,467 bp from pter
Size:
 1,422 bases      Orientation:
 plus strand

Proteins
for ACTRT2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ACTT2_HUMAN, Q8TDY3 (See protein sequence)
Recommended Name: Actin-related protein T2  
Size: 377 amino acids; 41702 Da
Subcellular location: Cytoplasm, cytoskeleton (By similarity)
Secondary accessions: B1AN52 Q8NHS6 Q8TDG1

Explore the universe of human proteins at neXtProt for ACTRT2: NX_Q8TDY3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TDY3

    • ACTRT2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_536356.3  
    ENSEMBL proteins: 
     ENSP00000367658  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: ACTRT2
    OriGene Protein Over-expression Lysate: ACTRT2
    OriGene Custom Protein Services for ACTRT2 
    GenScript Custom Purified and Recombinant Proteins Services for ACTRT2
    Novus Biologicals ACTRT2 Proteins
    Novus Biologicals ACTRT2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ACTRT2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--


    ACTRT2 for ontologies           About GeneDecksing



    ACTRT2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ACTRT2 
    GenScript Custom Superior Antibodies Services for ACTRT2
    Novus Biologicals ACTRT2 Antibodies
    Search for Antibodies for ACTRT2 at Abcam  
    Uscn Antibodies for ACTRT2
    Search ThermoFisher Antibodies for ACTRT2

    Assay Products for ACTRT2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ACTRT2
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for ACTRT2

    Protein Domains /
    Families
    for ACTRT2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ACTRT2 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR004000 Actin-related
     IPR020902 Actin/actin-like_CS

    Graphical View of Domain Structure for InterPro Entry Q8TDY3

    ProtoNet protein and cluster: Q8TDY3

    1 Blocks protein family: IPB004000 Actin/actin-like

    UniProtKB/Swiss-Prot: ACTT2_HUMAN, Q8TDY3
    Similarity: Belongs to the actin family


    Function
    for ACTRT2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    miRNA
    Products:            		Browse 3'-UTR reporter clones for miRNA target validation
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ACTRT2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ACTRT2
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ACTRT2 (see all 7)
    OriGene shRNA RFP: ACTRT2
    OriGene siRNA: ACTRT2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ACTRT2

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for ACTRT2

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACTRT2 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACTRT2
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: ACTRT2 (NM_080431)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACTRT2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACTRT2 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for ACTRT2
    Search LifeMap BioReagents cell lines for ACTRT2

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACTRT2

    2 GenomeRNAi human phenotypes for ACTRT2:
     Increased cell number in G1, s  Increased cilium length after  


    Pathways & Interactions
    for ACTRT2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ACTRT2

    Drugs & Compounds
    for ACTRT2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ACTRT2
    Search CenterWatch for drugs/clinical trials and news about ACTRT2 / ACTT2 

    Transcripts
    for ACTRT2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ACTRT2 gene: 
    NM_080431.4  

    Unigene Cluster for ACTRT2:

    Actin-related protein T2
    Hs.236635  [show with all ESTs]
    Unigene Representative Sequence: NM_080431
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000378404(uc001ajz.3)

    miRNA
    Products:             		Browse 3'-UTR reporter clones for miRNA target validation
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ACTRT2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ACTRT2
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ACTRT2 (see all 7)
    OriGene shRNA RFP: ACTRT2
    OriGene siRNA: ACTRT2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ACTRT2
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACTRT2 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACTRT2
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: ACTRT2 (NM_080431)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACTRT2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACTRT2 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ACTRT2
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ACTRT2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ACTRT2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ACTRT2

    Additional cDNA sequence: 

    AB057364.1 AF440740.1 AK314500.1 BC029499.1 

    1 DOTS entry:

    DT.97838015 

    24/29 AceView cDNA sequences (see all 29):

    AF440740 BP369024 NM_080431 AK058153 AB057364 AW016204 AL044118 BP371195 
    BI520482 BI827970 BI826376 BP370273 BI825639 AL044119 BP370015 AW003563 
    BM563549 BC029499 AI968198 BI825625 AI655275 BI463106 AA397903 BI460134 

    GeneLoc Exon Structure


    Expression
    for ACTRT2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ACTRT2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CAGCTGCTCC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ACTRT2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BoneStylopod Long BoneBone
    CartilageMeckel's CartilageCartilage
    LiverLiver LobuleLiver
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Blimp1- mVenus and stella-ECFP genetically modified stem cells (Embryonic Stem Cell)Early Embryo, Inner Cell Mass

    See ACTRT2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ACTRT2

    SOURCE GeneReport for Unigene cluster: Hs.236635
        SABiosciences Custom PCR Arrays for ACTRT2
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ACTRT2
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ACTRT2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ACTRT2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ACTRT2
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACTRT2

    Orthologs
    for ACTRT2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ACTRT2 gene from 7/26 species (see all 26)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves ACTRT21 actin-related protein T2 62.77(n)
    53.46(a)    		   428178  XM_425736.3  XP_425736.1 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    ACTR1A6
    (see all 5)    		 --
    		 53(a)
    41(a)
    (see all 5)    		 1 ↔ many
    possible ortholog
    (see all 5)    		 AAWZ02039666(5467-6588)
    AAWZ02038352(1873-11960)
    zebrafish
    (Danio rerio)    		 Actinopterygii actr16
    actr2a6
    (see all 5)    		 ARP2 actin-related protein 2a homolog (yeast)
    (see all 5)    		 40(a)
    35(a)
    (see all 5)    		 possible ortholog
    possible ortholog
    (see all 5)    		 10(43887068-43905964)
    1(51916360-51936946)
    fruit fly
    (Drosophila melanogaster)    		 Insecta Arp87C6
    Arp14D6
    		 Actin-related protein 14D
    		 42(a)
    34(a)
    		 possible ortholog
    possible ortholog
    		 3R(8517458-8519954)
    X(16442323-16448001)
    worm
    (Caenorhabditis elegans)    		 Secernentea arp-16
    arx-26
    		 Actin-related protein 2
    		 40(a)
    36(a)
    		 possible ortholog
    possible ortholog
    		 II(15120223-15123270)
    V(10335241-10338334)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons ARP26
    		 actin related protein 2
    		 34(a)
    		 possible ortholog
    		 3(9952563-9955941)
    rice
    (Oryza sativa)    		 Liliopsida --
    		 actin, putative, expressed
    		 33(a)
    		 possible ortholog
    		 8(17201864-17206657)


    ENSEMBL Gene Tree for ACTRT2 (if available)
    TreeFam Gene Tree for ACTRT2 (if available) 

    Paralogs
    for ACTRT2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ACTRT2 gene
    ACTG22  ACTA22  ACTB2  ACTR1A2  ACTC12  ACTL92  ACTRT12  ACTG12  
    ACTL7A2  ACTBL22  ACTL7B2  ACTR1B2  ACTA12  ACTRT32  
    18/28 SIMAP similar genes for ACTRT2 using alignment to 1 protein entry:     ACTT2_HUMAN(see all similar genes):
    ACTRT1    ACTRT3    ACTG1    ACTB    ACTG2    PS1TP5BP1
    ACTA2    ACTR1A    ACTBL2    ACTC1    POTEF    POTEI
    POTEJ    ACTR1B    POTEE    POTEKP    ACTL7B    ACTL7A

    ACTRT2 for paralogs           About GeneDecksing



    Genomic Variants
    for ACTRT2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/134 NCBI SNPs in ACTRT2 are shown (see all 134)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1862241491,2
    		--2936046(+) GTTGTA/GCAGGT 1 -- us2k10--------
    rs1901448921,2
    		--2936112(+) TCAGCA/GAGGAG 1 -- us2k10--------
    rs1151342421,2
    		C,F,--2936163(+) TGGCTG/ACATGG 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1383702411,2
    		--2936256(+) TGCCCA/GTGCAC 1 -- us2k10--------
    rs1438404231,2
    		--2936385(+) CTGCCC/TCGGGA 1 -- us2k10--------
    rs125644561,2
    		C,F,A,H,--2936386(+) TGCCCC/GGGGAC 1 -- us2k18Minor allele frequency- G:0.28WA NA EA 368
    rs1827228961,2
    		--2936420(+) GCCTCA/CGGTGA 1 -- us2k10--------
    rs107527321,2
    		C,F,H,--2936480(+) CAGCGC/TCTGGG 1 -- us2k1 tfbs322Minor allele frequency- T:0.05NA NS EA WA CSA 1809
    rs1152585611,2
    		F,--2936544(+) GCCTCC/TGTCCA 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs726294831,2
    		C,--2936678(+) CAGTTC/TCCCTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ACTRT2 (2938046 - 2939467 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ACTRT2: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ACTRT2
    DNA2.0 Custom Variant and Variant Library Synthesis for ACTRT2

    Disorders / Diseases
    for ACTRT2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ACTRT2 for disorders           About GeneDecksing

    OMIM gene information: 608535    OMIM disorders: --

    1 disease for ACTRT2:    About MalaCards
    malaria


    Export disorders for ACTRT2 gene to outside databases

    Publications
    for ACTRT2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ACTRT2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ACTRT2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Novel actin-related proteins Arp-T1 and Arp-T2 as components of the cytoskeletal calyx of the mammalian sperm head. (PubMed id 12243744)1, 2, 3, 9 Heid H....Franke W. (2002)
    2. Identification of two cDNAs for human actin-related proteins (Arps) that have remarkable similarity to conventional actin. (PubMed id 11750065)1, 2, 3 Harata M.... Hatta S. (2001)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
    6. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for ACTRT2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing ACTRT2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 140625 HGNC: 24026 AceView: ARPM2 Ensembl:ENSG00000169717 euGenes: HUgn140625
    ECgene: ACTRT2 H-InvDB: ACTRT2

    Other Databases showing ACTRT2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ACTRT2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ACTRT2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ACTRT2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ACTRT2 gene:
    Search GeneIP for patents involving ACTRT2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for ACTRT2 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for ACTRT2  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ACTRT2   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ACTRT2  
     OriGene Protein Over-expression Lysate for ACTRT2   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for ACTRT2   Browse 3'-UTR reporter clones for miRNA target validation  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACTRT2   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACTRT2  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for ACTRT2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ACTRT2   OriGene Custom Protein Services for ACTRT2  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ACTRT2
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ACTRT2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACTRT2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ACTRT2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ACTRT2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ACTRT2
     GenScript Custom Purified and Recombinant Proteins Services for ACTRT2 GenScript cDNA clones with any tag delivered in your preferred vector for ACTRT2
     GenScript Custom Assay Services for ACTRT2 GenScript Custom Superior Antibodies Services for ACTRT2
     GenScript Custom overexpressing Cell Line Services for ACTRT2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ACTRT2 promoter
     Search Chromatin IP Primers for ACTRT2
     RT2 qPCR Primer Assay in human, mouse, rat ACTRT2
     Search GNC Networks for ACTRT2
     SABiosciences Custom PCR Arrays for ACTRT2
     Search Tocris compounds for ACTRT2
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ACTRT2 antibodies
     ACTRT2 proteins
     ACTRT2 lysates
     Search for Antibodies for ACTRT2 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for ACTRT2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     ACTRT2 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for ACTRT2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACTRT2
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ACTRT2
     SwitchGear Promoter luciferase reporter plasmids for ACTRT2
     Search ThermoFisher Antibodies for ACTRT2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACTRT2
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      ACTRT2 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4