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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ACTR3B Gene

protein-coding   GIFtS: 55
GCID: GC07P152456

ARP3 Actin-Related Protein 3 Homolog B (Yeast)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ARP3 Actin-Related Protein 3 Homolog B (Yeast)1 2     ARP3BETA2
Actin-Like Protein 3B2 3     Actin-Related Protein 3-Beta2
Actin-Related Protein ARP42 3     Actin-Related Protein 3B2
ARP112 3     Actin-Related Protein Arp112
ARP3-beta2 3     ARP43

External Ids:    HGNC: 172561   Entrez Gene: 571802   Ensembl: ENSG000001336277   UniProtKB: Q9P1U13   

Export aliases for ACTR3B gene to outside databases

Previous GC identifers: GC07P151895 GC07P152087 GC07P146267


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ACTR3B Gene:
This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55%
amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the
actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes
2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms.
(provided by RefSeq, Jul 2012)

GeneCards Summary for ACTR3B Gene: 
ACTR3B (ARP3 actin-related protein 3 homolog B (yeast)) is a protein-coding gene. Diseases associated with ACTR3B include lung adenocarcinoma, and down syndrome, and among its related super-pathways are Development Slit-Robo signaling and Immune response CCR3 signaling in eosinophils. GO annotations related to this gene include actin binding and ATP binding. An important paralog of this gene is ACTR3C.

UniProtKB/Swiss-Prot: ARP3B_HUMAN, Q9P1U1
Function: Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the
Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating
nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic
potential of tumors

Gene Wiki entry for ACTR3B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007914.15  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ACTR3B gene promoter:
         Max1   Sp1   Lmo2   RelA   NF-kappaB   E4BP4   POU2F1   POU2F1a   NF-kappaB1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): ACTR3B promoter sequence
   Search SABiosciences Chromatin IP Primers for ACTR3B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACTR3B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q36.1   Ensembl cytogenetic band:  7q36.1   HGNC cytogenetic band: 7q36.1

ACTR3B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACTR3B gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P152456:  view genomic region     (about GC identifiers)

Start:
152,456,834 bp from pter      End:
152,552,463 bp from pter
Size:
95,630 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 151,783,931-151,879,543     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ARP3B_HUMAN, Q9P1U1 (See protein sequence)
Recommended Name: Actin-related protein 3B  
Size: 418 amino acids; 47608 Da
Subunit: Interacts with the Arp2/3 complex composed of ARP2, ARP3, ARPC1B, ARPC1B/p41-ARC, ARPC2/p34-ARC,
ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC
Subcellular location: Cytoplasm, cytoskeleton (By similarity). Cell projection (By similarity)
Sequence caution: Sequence=AAP97150.1; Type=Frameshift; Positions=Several;
Secondary accessions: A8MTG1 B4DFW4 Q7Z526 Q96BT2
Alternative splicing: 3 isoforms:  Q9P1U1-1   Q9P1U1-2   Q9P1U1-3   

Explore the universe of human proteins at neXtProt for ACTR3B: NX_Q9P1U1

Explore proteomics data for ACTR3B at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9P1U1

  • ACTR3B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ACTR3B Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001035225.1  NP_065178.1  

    ENSEMBL proteins: 
     ENSP00000367007   ENSP00000256001   ENSP00000380452   ENSP00000446157  

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    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--
    GO:0005885Arp2/3 protein complex ----
    GO:0042995cell projection IEA--

    ACTR3B for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR015623 Arp3
     IPR004000 Actin-related
     IPR020902 Actin/actin-like_CS

    Graphical View of Domain Structure for InterPro Entry Q9P1U1

    ProtoNet protein and cluster: Q9P1U1

    1 Blocks protein domain: IPB004000 Actin/actin-like

    UniProtKB/Swiss-Prot: ARP3B_HUMAN, Q9P1U1
    Similarity: Belongs to the actin family. ARP3 subfamily


    ACTR3B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARP3B_HUMAN, Q9P1U1
    Function: Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the
    Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating
    nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic
    potential of tumors

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
    GO:0005524ATP binding IEA--
         
    ACTR3B for ontologies           About GeneDecksing


    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidACTR3B 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ACTR3B About   (see all 8)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Development Slit-Robo signaling
    Development Slit-Robo signaling0.92
    Cytoskeleton remodeling Slit-Robo signaling0.92
    2Immune response CCR3 signaling in eosinophils
    Immune response CCR3 signaling in eosinophils0.51
    Inhibitory action of Lipoxins on neutrophil migration0.51
    3Cell adhesion Integrin-mediated cell adhesion and migration
    Cell adhesion Integrin-mediated cell adhesion and migration0.49
    Cytoskeleton remodeling Integrin outside-in signaling0.37
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases0.49
    Cytoskeleton remodeling Fibronectin-binding integrins in cell motility0.32
    4Cytoskeleton remodeling CDC42 in cellular processes
    G-protein signaling RAC1 in cellular process0.37
    Cytoskeleton remodeling CDC42 in cellular processes0.37
    5Immune response Fc epsilon RI pathway
    Immune response Role of DAP12 receptors in NK cells0.32
    Immune response CD16 signaling in NK cells0.32

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    5/13 EMD Millipore Pathways for ACTR3B (see all 13)
        Cytoskeleton remodeling Integrin outside-in signaling
    Immune response CD16 signaling in NK cells
    Cytoskeleton remodeling CDC42 in cellular processes
    Cytoskeleton remodeling Fibronectin-binding integrins in cell motility
    Immune response Role of DAP12 receptors in NK cells


    5/14 GeneGo (Thomson Reuters) Pathways for ACTR3B (see all 14)
        Cytoskeleton remodeling CDC42 in cellular processes
    Immune response CD16 signaling in NK cells
    Cytoskeleton remodeling Fibronectin-binding integrins in cell motility
    Neurophysiological process Receptor-mediated axon growth repulsion
    Cytoskeleton remodeling Integrin outside-in signaling



    ACTR3B for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ACTR3B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    5/64 Interacting proteins for ACTR3B (Q9P1U12, 3 ENSP000002560014) via UniProtKB, MINT, STRING, and/or I2D (see all 64)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RSRC1Q96IZ72, 3, ENSP000002959304MINT-65197 I2D: score=2 STRING: ENSP00000295930
    CALM1P621583I2D: score=1 
    CALM2P621583I2D: score=1 
    CALM3P621583I2D: score=1 
    ARPC5LQ9BPX53, ENSP000002594774I2D: score=2 STRING: ENSP00000259477
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0034314Arp2/3 complex-mediated actin nucleation ----

    ACTR3B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ACTR3B (ARP3B)

    Search CenterWatch for drugs/clinical trials and news about ACTR3B / ARP3B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    About This Section

    REFSEQ mRNAs for ACTR3B gene (2 alternative transcripts): 
    NM_001040135.2  NM_020445.5  

    Unigene Cluster for ACTR3B:

    ARP3 actin-related protein 3 homolog B (yeast)
    Hs.647117  [show with all ESTs]
    Unigene Representative Sequence: NM_020445
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377776 ENST00000256001(uc003wle.1 uc003wlf.1 uc003wlg.1 uc011kvp.1)
    ENST00000397282 ENST00000488782 ENST00000479402 ENST00000537264
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    SwitchGear 3'UTR luciferase reporter plasmidACTR3B 3' UTR sequence
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    Additional mRNA sequence: 

    AF023453.1 AF086920.1 AK001198.1 AK294292.1 AK315534.1 AK316078.1 BC008682.1 BC015207.1 
    NR_073000.1 NR_073001.1 

    10 DOTS entries:

    DT.91721784  DT.95169715  DT.415316  DT.100793644  DT.91690511  DT.100793652  DT.100024668  DT.100793651 
    DT.95169722  DT.97768839 

    24/163 AceView cDNA sequences (see all 163):

    BM770889 BM758167 CR615185 W68288 BM772497 F12201 AU123641 AI124863 
    CR603830 BM981539 BX347822 BM452653 CR604196 H11255 BU621305 BM743306 
    AA772192 BM757530 BU727393 BM758029 BM758773 BQ214870 CA436326 BF724334 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ACTR3B (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b
    SP1:                                                                                                      
    SP2:                                                                          -     -     -               
    SP3:              -                                         -                                             
    SP4:                                            -                                                         
    SP5:                                                        -                                             


    ECgene alternative splicing isoforms for ACTR3B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ACTR3B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATCTTTTAG
    ACTR3B Expression
    About this image


    See ACTR3B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ACTR3B

    SOURCE GeneReport for Unigene cluster: Hs.647117

    UniProtKB/Swiss-Prot: ARP3B_HUMAN, Q9P1U1
    Tissue specificity: Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but
    not in white matter. Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with
    low metastatic potential, but not in lung adenocarcinoma cells with high metastatic potential

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACTR3B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ACTR3B gene from 9/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Actr3b1 , 5 ARP3 actin-related protein 3 homolog B (yeast)5
    ARP3 actin-related protein 3B1
    89.87(n)1
    98.56(a)1
      5 (12.35 cM)5
    2428941  NM_001004365.11  NP_001004365.11 
     257599975 
    chicken
    (Gallus gallus)
    Aves ACTR3B1 ARP3 actin-related protein 3 homolog B (yeast) 84.05(n)
    96.65(a)
      420439  XM_418544.3  XP_418544.1 
    lizard
    (Anolis carolinensis)
    Reptilia ACTR3B6
    Uncharacterized protein
    84(a)
    possible ortholog
    6(4522009-4550009)
    zebrafish
    (Danio rerio)
    Actinopterygii AY113680.12   -- 77.14(n)    AY113680.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Arp66B6
    Actin-related protein 66B
    79(a)
    possible ortholog
    3L(8106507-8109002)
    worm
    (Caenorhabditis elegans)
    Secernentea arx-16
    Actin-related protein 3
    71(a)
    possible ortholog
    I(2883496-2893718)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ARP3(YJR065C)4 Essential component of the Arp2/3 complex, which is more   --   10(559158-557809) 853528  NP_012599.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons DIS11 actin-related protein 3 59.93(n)
    61.82(a)
      837876  NM_101188.2  NP_172777.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g05969001 hypothetical protein 58.25(n)
    59.8(a)
      4329867  NM_001053858.1  NP_001047323.1 


    ENSEMBL Gene Tree for ACTR3B (if available)
    TreeFam Gene Tree for ACTR3B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ACTR3B gene
    ACTR3C2  ACTR32  
    18/25 SIMAP similar genes for ACTR3B using alignment to 1 protein entry:     ARP3B_HUMAN(see all similar genes):
    ACTR3C    ACTR3    FKSG72    FKSG73    FKSG74    ACTR1A
    ACTG1    ACTR1B    ACTR2    POTEM    ACTA2    ACTB
    ACTBL2    ACTC1    ACTG2    POTEE    POTEF    POTEI

    ACTR3B for paralogs           About GeneDecksing


    5/7 Pseudogenes.org Pseudogenes for ACTR3B (see all 7)
    PGOHUM00000238743 PGOHUM00000248822 PGOHUM00000246380 PGOHUM00000240774 PGOHUM00000238117


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2024 SNPs in ACTR3B are shown (see all 2024)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1899478251,2
    --152454962(+) TCATGC/G/TAGATC 4 -- us2k10--------
    rs1408344911,2
    C--152454990(+) TGTGAA/CTAGTC 4 -- us2k10--------
    rs1139801601,2
    F--152455000(+) CGCTGC/ACCTCC 4 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1160174261,2
    C,F--152455040(+) CTAAGA/CAACAA 4 -- us2k11Minor allele frequency- C:0.01WA 118
    rs1501313081,2
    --152455202(+) CAGTTC/TTCCTG 4 -- us2k10--------
    rs1882615851,2
    --152455264(+) AATGAG/TGATGG 4 -- us2k10--------
    rs1456463961,2
    --152455293(+) ACGTAA/TCTATT 4 -- us2k10--------
    rs1174126321,2
    F--152455358(+) GCTGGG/CCGTGG 4 -- us2k11Minor allele frequency- C:0.05NA 120
    rs1403823771,2
    C--152455506(+) TGGGTA/GCCTGT 4 -- us2k10--------
    rs1452802641,2
    --152455598(+) CTGCAC/GTCCAG 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for ACTR3B (152456834 - 152552463 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ACTR3B:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2735460CNV Deletion23290073
    nsv889506CNV Loss21882294
    nsv831193CNV Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for ACTR3B:    About MalaCards
    lung adenocarcinoma    down syndrome    adenocarcinoma    neuronitis


    ACTR3B for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for ACTR3B gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adenocarcinoma lung 66.2 3 14651955 (2), 11162478 (1)

    Genetic Association Database (GAD): ACTR3B
    Human Genome Epidemiology (HuGE) Navigator: ACTR3B (1 document)

    Export disorders for ACTR3B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ACTR3B gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with ACTR3B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ARP3beta, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells. (PubMed id 10806390)1, 2, 3, 9 Jay P.... Berta P. (2000)
    2. Expression of the Arp11 gene suppresses the tumorigenicity of PC-14 human lung adenocarcinoma cells. (PubMed id 14651955)1, 2, 9 Shindo-Okada N. and Iigo M. (2003)
    3. Isolation of a novel actin-related gene expressed in low-metastatic PC-14 human lung adenocarcinoma. (PubMed id 11162478)1, 2, 9 Shindo-Okada N. and Shimizu K. (2001)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    7. Derangement of hypothetical proteins in fetal Down's syndrome brain. (PubMed id 15176487)1, 9 Shin J.H....Lubec G. (2004)
    8. The P-body component USP52/PAN2 is a novel regulator o f HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (2013)
    9. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (2012)
    10. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57180 HGNC: 17256 AceView: ARP3BETA Ensembl:ENSG00000133627 euGenes: HUgn57180
    ECgene: ACTR3B H-InvDB: ACTR3B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ACTR3B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ACTR3B gene:
    Search GeneIP for patents involving ACTR3B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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