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ACTR3B Gene

protein-coding   GIFtS: 54
GCID: GC07P152456

ARP3 Actin-Related Protein 3 Homolog B (Yeast)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ARP3 Actin-Related Protein 3 Homolog B (Yeast)1 2     ARP3BETA2
Actin-Like Protein 3B2 3     Actin-Related Protein 3-Beta2
Actin-Related Protein ARP42 3     Actin-Related Protein 3B2
ARP112 3     Actin-Related Protein Arp112
ARP3-beta2 3     ARP43

External Ids:    HGNC: 172561   Entrez Gene: 571802   Ensembl: ENSG000001336277   UniProtKB: Q9P1U13   

Export aliases for ACTR3B gene to outside databases

Previous GC identifers: GC07P151895 GC07P152087 GC07P146267


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ACTR3B Gene:
This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55%
amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the
actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes
2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms.
(provided by RefSeq, Jul 2012)

GeneCards Summary for ACTR3B Gene:
ACTR3B (ARP3 actin-related protein 3 homolog B (yeast)) is a protein-coding gene. GO annotations related to this gene include actin binding. An important paralog of this gene is ACTR3C.

UniProtKB/Swiss-Prot: ARP3B_HUMAN, Q9P1U1
Function: Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the
Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating
nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic
potential of tumors

Gene Wiki entry for ACTR3B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ACTR3B gene promoter:
         Max1   Sp1   Lmo2   RelA   NF-kappaB   E4BP4   POU2F1   POU2F1a   NF-kappaB1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): ACTR3B promoter sequence
   Search Chromatin IP Primers for ACTR3B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ACTR3B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q36.1   Ensembl cytogenetic band:  7q36.1   HGNC cytogenetic band: 7q36.1

ACTR3B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACTR3B gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P152456:  view genomic region     (about GC identifiers)

Start:
152,456,834 bp from pter      End:
152,552,463 bp from pter
Size:
95,630 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 151,783,931-151,879,543     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ARP3B_HUMAN, Q9P1U1 (See protein sequence)
Recommended Name: Actin-related protein 3B  
Size: 418 amino acids; 47608 Da
Subunit: Interacts with the Arp2/3 complex composed of ARP2, ARP3, ARPC1B, ARPC1B/p41-ARC, ARPC2/p34-ARC,
ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC
Sequence caution: Sequence=AAP97150.1; Type=Frameshift; Positions=Several;
Secondary accessions: A8MTG1 B4DFW4 Q7Z526 Q96BT2
Alternative splicing: 3 isoforms:  Q9P1U1-1   Q9P1U1-2   Q9P1U1-3   

Explore the universe of human proteins at neXtProt for ACTR3B: NX_Q9P1U1

Explore proteomics data for ACTR3B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ACTR3B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001035225.1  NP_065178.1  

    ENSEMBL proteins: 
     ENSP00000367007   ENSP00000256001   ENSP00000380452   ENSP00000446157  

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    antibodies-online peptides for ACTR3B

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR020902 Actin/actin-like_CS
     IPR004000 Actin-related

    Graphical View of Domain Structure for InterPro Entry Q9P1U1

    ProtoNet protein and cluster: Q9P1U1

    1 Blocks protein domain: IPB004000 Actin/actin-like

    UniProtKB/Swiss-Prot: ARP3B_HUMAN, Q9P1U1
    Similarity: Belongs to the actin family. ARP3 subfamily


    Find genes that share domains with ACTR3B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARP3B_HUMAN, Q9P1U1
    Function: Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the
    Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating
    nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic
    potential of tumors

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
    GO:0005524ATP binding IEA--
         
    Find genes that share ontologies with ACTR3B           About GenesLikeMe


    Animal Models:
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    hsa-miR-3163 hsa-miR-3149 hsa-miR-520d-5p hsa-miR-1197 hsa-miR-485-3p hsa-miR-135b hsa-miR-3119 hsa-miR-524-5p
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ARP3B_HUMAN, Q9P1U1: Cytoplasm, cytoskeleton (By similarity). Cell projection (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    cytoskeleton2
    nucleus2
    mitochondrion1
    plasma membrane1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--
    GO:0005885Arp2/3 protein complex ----
    GO:0042995cell projection IEA--

    Find genes that share ontologies with ACTR3B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ACTR3B About   (see all 7)  
    See pathways by source

    SuperPathContained pathways About
    1Development Slit Robo signaling
    Development Slit Robo signaling0.92
    Neurophysiological process Receptor mediated axon growth repulsion0.41
    Cytoskeleton remodeling Slit Robo signaling0.92
    2Immune response CCR3 signaling in eosinophils
    Inhibitory action of Lipoxins on neutrophil migration0.51
    Immune response CCR3 signaling in eosinophils0.51
    3Cell adhesion Integrin mediated cell adhesion and migration
    Cell adhesion Integrin mediated cell adhesion and migration0.49
    Cytoskeleton remodeling Integrin outside in signaling0.37
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases0.49
    Cytoskeleton remodeling Fibronectin binding integrins in cell motility0.32
    4G protein signaling RAC1 in cellular process
    G protein signaling RAC1 in cellular process0.37
    Cytoskeleton remodeling CDC42 in cellular processes0.37
    5Immune response Role of DAP12 receptors in NK cells
    Immune response Role of DAP12 receptors in NK cells0.33
    Immune response CD16 signaling in NK cells0.33

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    Selected GeneGo (Thomson Reuters) Pathways for ACTR3B (see all 14)
        Cytoskeleton remodeling CDC42 in cellular processes
    Immune response CD16 signaling in NK cells
    Cytoskeleton remodeling Fibronectin-binding integrins in cell motility
    Neurophysiological process Receptor-mediated axon growth repulsion
    Cytoskeleton remodeling Integrin outside-in signaling


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ACTR3B
    Interactions:

        Search GeneGlobe Interaction Network for ACTR3B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ACTR3B (Q9P1U12, 3 ENSP000002560014) via UniProtKB, MINT, STRING, and/or I2D (see all 139)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RSRC1Q96IZ72, 3, ENSP000002959304MINT-65197 I2D: score=2 STRING: ENSP00000295930
    CALM1P621583, ENSP000003494674I2D: score=1 STRING: ENSP00000349467
    CALM2P621583, ENSP000002722984I2D: score=1 STRING: ENSP00000272298
    CALM3P621583, ENSP000002912954I2D: score=1 STRING: ENSP00000291295
    ARPC5LQ9BPX53, ENSP000002594774I2D: score=2 STRING: ENSP00000259477
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0034314Arp2/3 complex-mediated actin nucleation ----

    Find genes that share ontologies with ACTR3B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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      Browse compounds at ApexBio 

    Browse Tocris compounds for ACTR3B (ARP3B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ACTR3B gene (2 alternative transcripts): 
    NM_001040135.2  NM_020445.5  

    Unigene Cluster for ACTR3B:

    ARP3 actin-related protein 3 homolog B (yeast)
    Hs.647117  [show with all ESTs]
    Unigene Representative Sequence: NM_020445
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377776 ENST00000256001(uc003wle.1 uc003wlf.1 uc003wlg.1 uc011kvp.1)
    ENST00000397282 ENST00000488782 ENST00000479402 ENST00000537264
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    hsa-miR-3163 hsa-miR-3149 hsa-miR-520d-5p hsa-miR-1197 hsa-miR-485-3p hsa-miR-135b hsa-miR-3119 hsa-miR-524-5p
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    Additional mRNA sequence: 

    AF023453.1 AF086920.1 AK001198.1 AK294292.1 AK315534.1 AK316078.1 BC008682.1 BC015207.1 
    NR_073000.1 NR_073001.1 

    10 DOTS entries:

    DT.91721784  DT.95169715  DT.415316  DT.100793644  DT.91690511  DT.100793652  DT.100024668  DT.100793651 
    DT.95169722  DT.97768839 

    Selected AceView cDNA sequences (see all 163):

    CB154628 CR604196 BM743306 AI923556 BM557095 BM759382 H11255 BM981539 
    BM757990 AK001198 BM770889 AA772192 BM758773 W68288 BM749853 BM747206 
    AI124863 BM452653 CR603830 BM758029 CR615185 BM758023 CB152786 AU123641 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ACTR3B (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b
    SP1:                                                                                                      
    SP2:                                                                          -     -     -               
    SP3:              -                                         -                                             
    SP4:                                            -                                                         
    SP5:                                                        -                                             


    ECgene alternative splicing isoforms for ACTR3B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ACTR3B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATCTTTTAG
    ACTR3B Expression
    About this image

    ACTR3B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ACTR3B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.647117

    UniProtKB/Swiss-Prot: ARP3B_HUMAN, Q9P1U1
    Tissue specificity: Detected in fetal brain. Detected throughout the adult brain, in neurons from gray matter, but
    not in white matter. Detected in liver, skeletal muscle and pancreas. Detected in lung adenocarcinoma cells with
    low metastatic potential, but not in lung adenocarcinoma cells with high metastatic potential

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACTR3B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ACTR3B gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Actr3b1 , 5 ARP3 actin-related protein 3 homolog B (yeast)5
    ARP3 actin-related protein 3B1
    89.87(n)1
    98.56(a)1
      5 (12.35 cM)5
    2428941  NM_001004365.11  NP_001004365.11 
     257599975 
    chicken
    (Gallus gallus)
    Aves ACTR3B1 ARP3 actin-related protein 3 homolog B (yeast) 84.05(n)
    96.65(a)
      420439  XM_418544.4  XP_418544.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    84(a)
    1 → many
    6(4522009-4550009)
    zebrafish
    (Danio rerio)
    Actinopterygii AY113680.12   -- 77.14(n)    AY113680.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Arp66B6
    Actin-related protein 66B
    76(a)
    1 → many
    3L(8106507-8109002)
    worm
    (Caenorhabditis elegans)
    Secernentea arx-16
    Protein ARX-1 (arx-1) mRNA, complete cds
    69(a)
    1 → many
    I(2883496-2893718) WBGene00000199
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ARP3(YJR065C)4 Essential component of the Arp2/3 complex, which is more   --   10(559158-557809) 853528  NP_012599.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons DIS11 DIS1 59.82(n)
    61.61(a)
      837876  NM_101188.2  NP_172777.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g05969001 Os02g0596900 58.23(n)
    59.61(a)
      4329867  NM_001053858.1  NP_001047323.1 


    ENSEMBL Gene Tree for ACTR3B (if available)
    TreeFam Gene Tree for ACTR3B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ACTR3B gene
    ACTR3C2  ACTR32  
    Selected SIMAP similar genes for ACTR3B using alignment to 1 protein entry:     ARP3B_HUMAN(see all similar genes):
    ACTR3C    ACTR3    FKSG72    FKSG73    FKSG74    ACTR1A
    ACTG1    ACTR1B    ACTR2    POTEM    ACTA2    ACTB
    ACTBL2    ACTC1    ACTG2    POTEE    POTEF    POTEI

    Find genes that share paralogs with ACTR3B           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for ACTR3B (see all 7)
    PGOHUM00000238743 PGOHUM00000248822 PGOHUM00000246380 PGOHUM00000240774 PGOHUM00000238117


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ACTR3B (see all 2024)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1899478251,2
    --152454962(+) TCATGC/G/TAGATC 4 -- us2k10--------
    rs1408344911,2
    C--152454990(+) TGTGAA/CTAGTC 4 -- us2k10--------
    rs1139801601,2
    F--152455000(+) CGCTGC/ACCTCC 4 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1160174261,2
    C,F--152455040(+) CTAAGA/CAACAA 4 -- us2k11Minor allele frequency- C:0.01WA 118
    rs1501313081,2
    --152455202(+) CAGTTC/TTCCTG 4 -- us2k10--------
    rs1882615851,2
    --152455264(+) AATGAG/TGATGG 4 -- us2k10--------
    rs1456463961,2
    --152455293(+) ACGTAA/TCTATT 4 -- us2k10--------
    rs1174126321,2
    F--152455358(+) GCTGGG/CCGTGG 4 -- us2k11Minor allele frequency- C:0.05NA 120
    rs1403823771,2
    C--152455506(+) TGGGTA/GCCTGT 4 -- us2k10--------
    rs1452802641,2
    --152455598(+) CTGCAC/GTCCAG 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for ACTR3B (152456834 - 152552463 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ACTR3B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2735460CNV Deletion23290073
    nsv889506CNV Loss21882294
    nsv831193CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing ACTR3B
    DNA2.0 Custom Variant and Variant Library Synthesis for ACTR3B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ACTR3B           About GenesLikeMe

    1 Novoseek inferred disease relationship for ACTR3B gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adenocarcinoma lung 66.2 3 14651955 (2), 11162478 (1)

    Genetic Association Database (GAD): ACTR3B
    Human Genome Epidemiology (HuGE) Navigator: ACTR3B (1 document)

    Export disorders for ACTR3B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ACTR3B gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with ACTR3B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ARP3beta, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells. (PubMed id 10806390)1, 2, 3, 9 Jay P.... Berta P. (Eur. J. Biochem. 2000)
    2. Expression of the Arp11 gene suppresses the tumorigenicity of PC-14 human lung adenocarcinoma cells. (PubMed id 14651955)1, 2, 9 Shindo-Okada N. and Iigo M. (Biochem. Biophys. Res. Commun. 2003)
    3. Isolation of a novel actin-related gene expressed in low-metastatic PC-14 human lung adenocarcinoma. (PubMed id 11162478)1, 2, 9 Shindo-Okada N. and Shimizu K. (Biochem. Biophys. Res. Commun. 2001)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (Nature 2003)
    7. Derangement of hypothetical proteins in fetal Down's syndrome brain. (PubMed id 15176487)1, 9 Shin J.H....Lubec G. (Neurochem. Res. 2004)
    8. The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. (PubMed id 23398456)1 Bett J.S....Hay R.T. (Biochem. J. 2013)
    9. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57180 HGNC: 17256 AceView: ARP3BETA Ensembl:ENSG00000133627 euGenes: HUgn57180
    ECgene: ACTR3B H-InvDB: ACTR3B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ACTR3B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ACTR3B gene:
    Search GeneIP for patents involving ACTR3B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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