Aliases for ACTR3 Gene
Aliases for ACTR3 Gene
External Ids for ACTR3 Gene
- HGNC: 170
- Entrez Gene: 10096
- Ensembl: ENSG00000115091
- OMIM: 604222
- UniProtKB: P61158
Previous GeneCards Identifiers for ACTR3 Gene
- GC02P111853
- GC02P112568
- GC02P114554
- GC02P114742
- GC02P114363
- GC02P114647
- GC02P106964
Summaries for ACTR3 Gene
-
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2013]
GeneCards Summary for ACTR3 Gene
ACTR3 (ARP3 Actin Related Protein 3 Homolog) is a Protein Coding gene. Diseases associated with ACTR3 include Wiskott-Aldrich Syndrome. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and Immune response CCR3 signaling in eosinophils. GO annotations related to this gene include actin filament binding and structural constituent of cytoskeleton. An important paralog of this gene is ACTR3B.
UniProtKB/Swiss-Prot for ACTR3 Gene
-
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACTR3 Gene
Genomics for ACTR3 Gene
Regulatory Elements for ACTR3 Gene
Enhancers for ACTR3 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ACTR3 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ACTR3 gene promoter:
Regulatory Element Products
Genomic Location for ACTR3 Gene
- Chromosome:
- 2
- Start:
- 113,889,934 bp from pter
- End:
- 113,962,596 bp from pter
- Size:
- 72,663 bases
- Orientation:
- Plus strand
Genomic View for ACTR3 Gene
Genes around ACTR3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q14.1 by Ensembl
- 2q14.1 by Entrez Gene
- 2q14.1 by HGNC
ACTR3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ACTR3 Gene
Proteins for ACTR3 Gene
-
Protein details for ACTR3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P61158-ARP3_HUMAN
- Recommended name:
- Actin-related protein 3
- Protein Accession:
- P61158
- P32391
- Q53QM2
Protein attributes for ACTR3 Gene
- Size:
- 418 amino acids
- Molecular mass:
- 47371 Da
- Quaternary structure:
-
- Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Interacts with WHDC1. Interacts weakly with MEFV.
Protein Expression for ACTR3 Gene
Post-translational modifications for ACTR3 Gene
Other Protein References for ACTR3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for ACTR3
- Cell Signaling Technology (CST) Antibodies for ACTR3 (Arp3)
-
Custom Antibody ServicesOriGene Antibodies for ACTR3
- Novus Biologicals Antibodies for ACTR3
- Invitrogen Antibodies for ACTR3
- antibodies-online Antibodies for ACTR3: See all 45
- GeneTex ACTR3 antibody for ACTR3
-
Santa Cruz Biotechnology (SCBT) Antibodies for ACTR3
Protein Products
-
OriGene Purified Proteins for ACTR3
- Search Origene for MassSpec and Protein Over-expression Lysates for ACTR3
- Origene Custom Protein Services for ACTR3
- Sino Biological Cell Lysates for ACTR3
- Sino Biological Recombinant Proteins for ACTR3
- ProSpec Recombinant Proteins for ACTR3
- antibodies-online Proteins for ACTR3: See all 16
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ACTR3
Assay Products
- antibodies-online Kits for ACTR3: See all 21
No data available for DME Specific Peptides for ACTR3 Gene
Domains & Families for ACTR3 Gene
Gene Families for ACTR3 Gene
Protein Domains for ACTR3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ACTR3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P61158- Family:
-
- Belongs to the actin family. ARP3 subfamily.
Function for ACTR3 Gene
Molecular function for ACTR3 Gene
- UniProtKB/Swiss-Prot Function:
- Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003779 | actin binding | IEA | -- |
| GO:0005200 | structural constituent of cytoskeleton | IDA | 11741539 |
| GO:0005515 | protein binding | IPI | 20195357 |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0051015 | contributes_to actin filament binding | IDA | 11741539 |
Phenotypes for ACTR3 Gene
- MGI mutant phenotypes for ACTR3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ACTR3:
-
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased viability in esophageal squamous lineage
- Strongly decreased CFP-tsO45G cell surface transport
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Decreased IL-8 secretion
- Decreased Salmonella enterica Typhimurium ruffling
- Decreased Salmonella enterica Typhimurium invasion
- Decreased Salmonella enterica Typhimurium effector injection
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Decreased cell migration
- Increased cilium length after serum starvation
- Decreased Salmonella-containing vacuole maturation
- Decreased Salmonella enterica Typhimurium binding
- Increased cilium length
- Decreased Salmonella enterica Typhimurium membrane closure
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ACTR3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ACTR3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ACTR3 gene
- Search ViGene Biosciences for ACTR3
CRISPR Products
-
OriGene CRISPR knockouts for ACTR3
-
Santa Cruz Biotechnology (SCBT) CRISPR for ACTR3
- GenScript: Design CRISPR guide RNA sequences for ACTR3
miRNA for ACTR3 Gene
- miRTarBase miRNAs that target ACTR3
miRNA Products
- Search ViGene Biosciences for ACTR3
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ACTR3
- Browse OriGene Inhibitory RNA Products For ACTR3
-
ViGene Biosciences ready-to-package AAV shRNAs for ACTR3 gene
Clone Products
- Sino Biological Human cDNA Clone for ACTR3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ACTR3
- VectorBuilder custom plasmid, inducible vectors for ACTR3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACTR3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ACTR3
-
ViGene Biosciences adenoviral particle packaged cDNA for ACTR3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ACTR3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ACTR3 gene
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-12089) for ACTR3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ACTR3 Gene
Localization for ACTR3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ACTR3 Gene
- Cytoplasm, cytoskeleton. Cell projection. Note=In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes) (PubMed:19109554).
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytoskeleton | 5 |
| cytosol | 5 |
| nucleus | 2 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0005856 | cytoskeleton | IEA | -- |
| GO:0005885 | Arp2/3 protein complex | TAS,IEA | 9230079 |
| GO:0005903 | brush border | IEA | -- |
Pathways & Interactions for ACTR3 Gene
Pathways by source for ACTR3 Gene
1 Cell Signaling Technology pathway for ACTR3 Gene
4 BioSystems pathways for ACTR3 Gene
15 Reactome pathways for ACTR3 Gene
1 KEGG pathway for ACTR3 Gene
14 GeneGo (Thomson Reuters) pathways for ACTR3 Gene
20 Qiagen pathways for ACTR3 Gene
Interacting Proteins for ACTR3 Gene
Selected Interacting proteins:
ENSP00000263238
P61158-ARP3_HUMAN
for ACTR3 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006928 | movement of cell or subcellular component | TAS | 9230079 |
| GO:0007015 | actin filament organization | IEA | -- |
| GO:0007163 | establishment or maintenance of cell polarity | IEA | -- |
| GO:0008356 | asymmetric cell division | IEA | -- |
| GO:0016344 | meiotic chromosome movement towards spindle pole | IEA | -- |
No data available for SIGNOR curated interactions for ACTR3 Gene
Drugs & Compounds for ACTR3 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for ACTR3 Gene
mRNA/cDNA for ACTR3 Gene
- (2) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (669) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ACTR3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ACTR3
-
Santa Cruz Biotechnology (SCBT) CRISPR for ACTR3
- GenScript: Design CRISPR guide RNA sequences for ACTR3
miRNA Products
- Search ViGene Biosciences for ACTR3
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ACTR3
- Browse OriGene Inhibitory RNA Products For ACTR3
-
ViGene Biosciences ready-to-package AAV shRNAs for ACTR3 gene
Clone Products
- Sino Biological Human cDNA Clone for ACTR3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ACTR3
- VectorBuilder custom plasmid, inducible vectors for ACTR3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACTR3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
- eBioscience FlowRNA Probe Sets (VA1-12089) for ACTR3
Expression for ACTR3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Intermediate Mesoderm (Gastrulation Derivatives)
- Intestine (Gastrointestinal Tract)
- Bone (Muscoskeletal System)
-
Uterus (Reproductive System)
-
Colon (Gastrointestinal Tract)
-
Prostate (Endocrine System)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Kidney (Urinary System)
-
Testis (Reproductive System)
-
Adrenal Gland (Endocrine System)
-
Esophagus (Gastrointestinal Tract)
-
Stomach (Gastrointestinal Tract)
-
Liver (Hepatobiliary System)
-
Adipose (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for ACTR3 Gene
This gene is overexpressed in Whole Blood (x4.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ACTR3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ACTR3 Gene:
ACTR3SOURCE GeneReport for Unigene cluster for ACTR3 Gene:
Hs.433512Evidence on tissue expression from TISSUES for ACTR3 Gene
- Nervous system(4.9)
- Blood(4.8)
- Liver(4.6)
- Skin(3.7)
- Kidney(3.6)
- Lung(3.2)
- Intestine(2.9)
- Spleen(2.4)
- Lymph node(2.2)
- Bone marrow(2)
- Heart(2)
Primer Products
-
OriGene qPCR primer pairs for ACTR3
-
OriGene qPCR primer pairs and template standards for ACTR3
No data available for Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ACTR3 Gene
Orthologs for ACTR3 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ACTR3 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ARP3 35 |
|
OneToOne | |
| ACTR3B 34 |
|
||||
| cow (Bos Taurus) |
Mammalia | ACTR3 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Actr3 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Actr3 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ACTR3 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ACTR3 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ACTR3 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | actr3 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ACTR3 (1 of 2) 35 |
|
OneToMany | |
| ACTR3 (2 of 2) 35 |
|
OneToMany | |||
| actr3 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | Arp66B 36 35 |
|
||
| Arp3 34 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP005110 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | arx-1 34 35 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ARP3 34 35 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0B13904g 34 |
|
||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AFR419C 34 |
|
||
| barley (Hordeum vulgare) |
Liliopsida | Hv.5713 34 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | arp3 34 |
|
||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU01756 34 |
|
- Species where no ortholog for ACTR3 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ACTR3 Gene
(25) SIMAP similar genes for ACTR3 Gene using alignment to 6 proteins:
Pseudogenes.org Pseudogenes for ACTR3 Gene
Variants for ACTR3 Gene
| SNP ID | Clin | Chr 02 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000004537 | -- | 113,949,321(+) | TGCAG(C/T)GAGCC | intron-variant | |
| rs1000016442 | -- | 113,920,138(+) | GCCTG(G/T)CCTTG | intron-variant | |
| rs1000079442 | -- | 113,899,896(+) | GGGAG(C/T)TGTGG | intron-variant | |
| rs1000130646 | -- | 113,893,953(+) | GCCAC(A/G)ATTCA | intron-variant | |
| rs1000143841 | -- | 113,901,106(+) | CTGAG(A/G)TCGGG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3334973 | CNV | insertion | 20981092 |
| esv990446 | CNV | insertion | 20482838 |
| nsv1127757 | CNV | deletion | 24896259 |
| nsv479438 | CNV | novel sequence insertion | 20440878 |
| nsv508860 | CNV | insertion | 20534489 |
Residual Variation Intolerance Score:
29.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.08;
21.99% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ACTR3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ACTR3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACTR3 Gene
Disorders for ACTR3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| wiskott-aldrich syndrome |
|
Search ACTR3 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for ACTR3
No data available for UniProtKB/Swiss-Prot and Genatlas for ACTR3 Gene
Publications for ACTR3 Gene
- The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. (PMID: 9230079) Welch M.D. … Mitchison T.J. (J. Cell Biol. 1997) 2 3 4 64
- Functional genomic screen for modulators of ciliogenesis and cilium length. (PMID: 20393563) Kim J. … Gleeson J.G. (Nature 2010) 3 4 64
- Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PMID: 15592455) Rush J. … Comb M.J. (Nat. Biotechnol. 2005) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Interaction of cortactin and N-WASp with Arp2/3 complex. (PMID: 12176354) Weaver A.M. … Cooper J.A. (Curr. Biol. 2002) 3 22 64
Products for ACTR3 Gene
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- OriGene qPCR primer pairs and template standards for ACTR3
- OriGene qPCR primer pairs for ACTR3
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- GenScript: Design CRISPR guide RNA sequences for ACTR3
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- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ACTR3
- Cell Signaling Technology (CST) Antibodies for ACTR3 (Arp3)
- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for ACTR3
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- Sino Biological Antibodies
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for ACTR3
- Novus Biologicals proteins and lysates for ACTR3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ProSpec Recombinant Proteins for ACTR3
- Addgene plasmids for ACTR3
- antibodies-online Antibodies for ACTR3: See all 45
- antibodies-online Kits for ACTR3: See all 21
- antibodies-online Proteins for ACTR3: See all 16
- Search antibodies-online for peptides
- GeneTex ACTR3 antibody for ACTR3
- Search GeneTex for Proteins for ACTR3
- ViGene Biosciences adenoviral particle packaged cDNA for ACTR3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ACTR3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ACTR3 gene
- Search ViGene Biosciences for ACTR3
- Santa Cruz Biotechnology (SCBT) Antibodies for ACTR3
- Search Santa Cruz Biotechnology (SCBT) for ACTR3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ACTR3
- Horizon Cell Lines for ACTR3
- Cyagen custom Knockout/knockin (KOKI) mouse models for ACTR3
- VectorBuilder custom plasmid, inducible vectors for ACTR3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACTR3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ACTR3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
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