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ACTR2 Gene

protein-coding GIFtS: 56

GC02P065366

ARP2 actin-related protein 2 homolog (yeast)
(Previous names: ARP2 (actin-related protein 2, yeast) homolog )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
ARP2 ^¹, ², ³

Descriptions
ARP2 (actin-related protein 2, yeast) homolog ^¹
ARP2 actin-related protein 2 homolog (yeast) ^²
Actin-like protein 2 ^³
actin-related protein 2 ^²

External Ids
HGNC: 169¹
Entrez Gene: 10097²
UniProtKB: P61160³
Ensembl: ENSG00000138071⁷

Search outside databases for aliases for ACTR2 gene

Previous GC identifers: GC02P065588 GC02P065412 GC02P065429

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ACTR2:

The specific function of this gene has not yet been determined; however, the protein it encodes is

known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface

and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.

Two transcript variants encoding different isoforms have been found for this gene. [provided by

RefSeq]

UniProtKB/Swiss-Prot: ARP2_HUMAN, P61160

Function: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation

of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates

the formation of branched actin networks. Seems to contact the pointed end of the daughter actin

filament

Gene Wiki entry for ACTR2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ACTR2 gene

Entrez Gene cytogenetic band: 2p14 Ensembl cytogenetic band: 2p14 HGNC cytogenetic band: 2p14

ACTR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P065366: (about GC identifiers)

Start:	65,308,406 bp from pter
End:	65,351,891 bp from pter
Size:	43,486 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000002.10 NT_022184.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ARP2_HUMAN, P61160 (See protein sequence)

Recommended Name: Actin-related protein 2

Size: 394 amino acids; 44761 Da

Subunit: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC,

ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC

Subcellular location: Cytoplasm, cytoskeleton. Cell projection

Secondary accessions: O15142 Q96C82

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001005386.1 NP_005713.1

ENSEMBL proteins:

ENSP00000387136 ENSP00000367220 ENSP00000260641

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Arp2)
	Human Recombinant Proteins from Abnova (ACTR2)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005885	Arp2/3 protein complex	TAS	9230079
GO:0042995	cell projection	IEA	--

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Antibodies for ACTR2:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of ACTR2
	Sigma-Aldrich Antibody Arrays and Antibodies for ACTR2
	Browse R&D Systems for Antibodies
	Cell Signaling Technology (CST) Antibodies for ACTR2 (ARP2)
	Antibodies from Abcam (Arp2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ACTR2)
	Novus Biologicals Antibodies for ACTR2

Assays for ACTR2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P61160

ProtoNet protein and cluster: P61160

UniProtKB/Swiss-Prot: ARP2_HUMAN, P61160

Similarity: Belongs to the actin family. ARP2 subfamily

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ACTR2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ACTR2)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_005722

Applied Biosystems Silencer® siRNAs for ACTR2

Sigma-Aldrich siRNA for ACTR2

Sigma-Aldrich shRNA for ACTR2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ACTR2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001005386
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001005386
untagged cDNA clones in CMV expression vector (see all 3): NM_001005386

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001005386

UniProtKB/Swiss-Prot: ARP2_HUMAN, P61160

Function: Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation

of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates

the formation of branched actin networks. Seems to contact the pointed end of the daughter actin

filament

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000166	nucleotide binding	IEA	--
GO:0003779	actin binding	IEA	--
GO:0005515	protein binding	IPI	17353931
GO:0005524	ATP binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/9 Sigma-Aldrich "Your Favorite Gene" Pathways for ACTR2 (Your Favorite Gene powered by Ingenuity) (see all 9 )

Ephrin Receptor Signaling
Regulation of Actin-based Motility by Rho
Fc&gamma
Clathrin-mediated Endocytosis
Axonal Guidance Signaling

GeneDecks ACTR2 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for ACTR2

5/17 Interacting proteins for ACTR2 (ENSP00000367220³ P61160^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 17 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
WASL	O00401²	STRING (score=.861) MINT-72701
ACTR3B	Q9P1U1¹	EBI-353580, EBI-1047175
BAK1	Q16611¹	EBI-353580, EBI-519866
ARPC1B	ENSP00000252725³	STRING (score=.997)
ARPC5	ENSP00000352918³	STRING (score=.997)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006928	cell motion	TAS	9230079

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ACTR2
1 Novoseek chemical compound relationship for ACTR2 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
atp	7.96	5	11752435 (3), 17251352 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ACTR2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ACTR2)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_005722

Sigma-Aldrich siRNA for ACTR2

Sigma-Aldrich shRNA for ACTR2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001005386 NM_005722

REFSEQ mRNAs for ACTR2 gene (2 alternative transcripts):

NM_001005386.2 NM_005722.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001005386 NM_005722

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001005386
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001005386
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_001005386

Additional cDNA sequence:

AB462501.1 AF006082.1 AK025051.1 AK295157.1 AK301634.1 AK315205.1 AL049356.1 BC014546.1

BC036253.1 BX649080.1 CR593126.1

23 DOTS entries:

DT.101961003 DT.95156078 DT.75189376 DT.100877089 DT.100877083 DT.100877085 DT.95245735 DT.97801854

DT.95074926 DT.97791493 DT.99926655 DT.120826962 DT.121011729 DT.121011735 DT.121011911 DT.121011966

DT.97760126 DT.100649879 DT.100877081 DT.121011721 DT.121493112 DT.91786737 DT.95378282

24/845 AceView cDNA sequences (see all 845 ):

BM708911 BU542055 CF137112 AI753315 AW338305 CA416792 AI718624 CB854590

F07421 AL701801 BM450277 AL712920 BM463962 BU625727 CN480414 BU175810

AI023074 BQ424114 Z43370 BI962614 AI753490 BM090588 BX646697 F03430

highest scoring ESTs for ACTR2:

AF006082 AA007317 AA021093 AA026823 AA026955 AA034103 AA064957 AA075106 AA089505 AA134171

Unigene Cluster for ACTR2:

ARP2 actin-related protein 2 homolog (yeast)

Hs.719274 [show with all ESTs]

Unigene Representative Sequence: NM_001005386

GeneLoc Exon Structure

3 Ensembl transcripts including schematic representations:

ENST00000409926 ENST00000377982 ENST00000260641

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ACTR2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ACTR2

¹ / ² / ³

12 probe-sets matching ACTR2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
35733_at²^{, 3}	U95-A	1	1.00	1.00	0.99	1.08	AF006082	1.00	1.00	1.00	1
35734_at²^{, 3}	U95-A	1	1.00	1.00	0.97	0.92	AI935551	0.80	1.00	0.91	1
200728_at²	U133-A	1	1.00	1.00	--	--	--	--	--	--	--
200729_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_005722	0.60	1.00	0.82	1
200727_s_at²^{, 3}	U133-A	3	1.00	0.89	--	--	AA699583	0.80	1.00	0.91	1
234210_x_at*²^{, 3}	U133-B	2	1.00	0.95	--	--	AK025051	0.20	1.00	0.72	1
200728_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
200729_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
200727_s_at²	U133Plus2	3	1.00	0.89	--	--	--	--	--	--	--
1554390_s_at²	U133Plus2	3	1.00	0.55	--	--	--	--	--	--	--
1558015_s_at²	U133Plus2	3	1.00	0.53	--	--	--	--	--	--	--
234210_x_at*²	U133Plus2	2	1.00	0.95	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.719274
Expression variation in blood from EXPOLDB for ACTR2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ACTR2 gene from 5/22 species (see all 22 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ACTR2¹	--	ARP2 actin-related protein 2 homolog (yeast)	94.99(n) 100(a)	481396 XM_847614.1 XP_852707.1
chimpanzee (Pan troglodytes)	ACTR2¹	--	ARP2 actin-related protein 2 homolog (yeast)	99.83(n) 100(a)	746973 XM_001155450.1 XP_001155450.1
cow (Bos taurus)	ACTR2¹	--	ARP2 actin-related protein 2 homolog (yeast)	93.82(n) 100(a)	538486 XM_580624.3 XP_580624.3
rat (Rattus norvegicus)	Actr2¹	--	ARP2 actin-related protein 2 homolog (yeast)	90.78(n) 99.75(a)	289820 NM_001009268.1 NP_001009268.1
mouse (Mus musculus)	Actr2^{1, 5}	11 (31.50 cM)⁵	ARP2 actin-related protein 2 homolog (yeast)^{1, 5}	92.3(n)¹ 100(a)¹	66713¹ NM_146243.1¹ NP_666355.1¹ AA409782⁵ AA791742⁵ (see all 19)

About this table Species with no ortholog for ACTR2

ENSEMBL Gene Tree for ACTR2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ACTR2 gene

ACTR1A² ACTR1B² ARPM1² ENSG00000213985²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/306 NCBI SNPs in ACTR2 are shown (see all 306 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 77)

AB	SNP ID	Valid	Chr 2 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs2008312^1,2	A,C,F,H,O	65308148(-)	`GGCGCT/CGCTTA`	2	--	ng5¹		5	MN EU EA WA	602
--	rs268878^1,2	A,C,F,H,O	65351075(-)	`ATTCAT/GGGTTC`	2	--	ut3¹ ese³		20	EA NA EU WA	2288
--	rs11424^1,2	A,C,F,H,O	65349522(+)	`GGAAGC/GTTTGT`	2	--	ut3¹		9	MN NA EU EA WA	932
	rs869548^1,2	A,C,F,H	65307624(+)	`TCCTCC/TATGCA`	2	--	ng5¹		6	EU EA WA NA	600
--	rs268875^1,2	C,F,H,O	65349391(-)	`TATGAT/CGGGAA`	2	--	ut3¹ ese³		8	MN NA EU EA WA	744
--	rs12560^1,2	A,C,F,H	65349691(+)	`TAGTCA/GTAGTC`	2	--	ut3¹ ese³		10	MN EU EA WA NA	2432
--	rs11698^1,2	A,C,F	65350766(+)	`GAAAAA/GTAAAA`	2	--	ut3¹		2	MN	372
--	rs7247^1,2	A,C,F	65351844(+)	`ATGAAA/GTACTT`	2	--	ut3¹		2	MN	372
--	rs190577^1,2	A,C,F	65349648(-)	`GCCTAC/TAGGAA`	2	--	ut3¹ ese³		2	MN EA	1670
--	rs13812^1,2	A,C,F	65351186(-)	`CTACAT/CACGCG`	2	--	ut3¹ ese³		11	EA NA MN	532

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HapMap Linkage Disequilibrium images for ACTR2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 604221

4 Novoseek disease relationships for ACTR2 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
wiskott-aldrich syndrome	80.76	4	16638851 (2), 11598103 (1), 17277766 (1)
metastasis	5.25	8	17459058 (4), 16638851 (2)
cancer	0.00	6	17459058 (3), 16638851 (3)
tumors	0.00	4	14990971 (3), 16638851 (1)

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/78 PubMed articles for ACTR2 gene (see all 78 ):

The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. (PubMed id 9230079)^{2, 3, 4} Welch M.D....Mitchison T.J. (1997)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Reconstitution of human Arp2/3 complex reveals critical roles of individual subunits in complex structure and activity. (PubMed id 11741539)^{3, 4} Gournier H.... Welch M.D. (2001)
Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes. (PubMed id 9000076)^{3, 4} Welch M.D.... Mitchison T.J. (1997)
Coexpression of actin-related protein 2 and Wiskott-Aldrich syndrome family verproline-homologous protein 2 in adenocarcinoma of the lung. (PubMed id 16638851)^{1, 3} Semba S....Mukai K. (2006)
Correlation between liver metastasis of the colocalization of actin-related protein 2 and 3 complex and WAVE2 in colorectal carcinoma. (PubMed id 17459058)^{1, 3} Iwaya K....Mukai K. (2007)
Actin-related protein (Arp2) inserts into artificial lipid membranes. (PubMed id 12468383)^{1, 3} Goldmann W.H. and Isenberg G. (2002)
Interaction of cortactin and N-WASp with Arp2/3 complex. (PubMed id 12176354)^{1, 3} Weaver A.M....Cooper J.A. (2002)
Involvement of Arp2/3 complex in MCP-1-induced chemotaxis. (PubMed id 16004967)^{1, 3} Mukai Y....Mukai K. (2005)
The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches. (PubMed id 9210376)^{1, 3} Winter D....Li R. (1997)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 10097	HGNC: 169	AceView: ACTR2	Ensembl:ENSG00000138071	euGenes: HUgn10097
ECgene: ACTR2	H-InvDB: ACTR2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for ACTR2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ACTR2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ACTR2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ACTR2		Antibodies for ACTR2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ACTR2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (ACTR2)
	Antibodies (ACTR2)
	Chimera RNAi (ACTR2)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for ACTR2 (ARP2)

	Recombinant Proteins (Arp2)
	Antibodies (Arp2)

Search OriGene for ACTR2

Search Tocris compounds for ACTR2

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ACTR2

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

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ACTR2 Gene

protein-coding GIFtS: 56

Aliases &
Descriptions
for ACTR2

Summaries
for ACTR2

Genomic Location
for ACTR2

Proteins
for ACTR2

Protein Domains/
Families
for ACTR2

Gene Function
for ACTR2

Pathways & Interactions
for ACTR2

Drugs & Compounds
for ACTR2

Transcripts
for ACTR2

Expression
for ACTR2

Orthologs
for ACTR2

Paralogs
for ACTR2

SNPs/Variants
for ACTR2

Disorders & Mutations
for ACTR2

Medical News
for ACTR2

Publications
for ACTR2

Search for ACTR2

Genome Databases showing ACTR2

Other Databases showing ACTR2

Specialized Databases showing ACTR2

Licensable Technologies
for ACTR2

Services
for ACTR2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ACTR2 Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor ACTR2

Summariesfor ACTR2

Genomic Locationfor ACTR2

Proteinsfor ACTR2

Protein Domains/Familiesfor ACTR2

Gene Functionfor ACTR2

Pathways & Interactionsfor ACTR2

Drugs & Compoundsfor ACTR2

Transcriptsfor ACTR2

Expression for ACTR2

Orthologsfor ACTR2

Paralogsfor ACTR2

SNPs/Variantsfor ACTR2

Disorders & Mutationsfor ACTR2

Medical Newsfor ACTR2

Publicationsfor ACTR2

Search for ACTR2

Genome Databases showing ACTR2

Other Databases showing ACTR2

Specialized Databases showing ACTR2

Licensable Technologiesfor ACTR2

Servicesfor ACTR2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ACTR2

Summaries
for ACTR2

Genomic Location
for ACTR2

Proteins
for ACTR2

Protein Domains/
Families
for ACTR2

Gene Function
for ACTR2

Pathways & Interactions
for ACTR2

Drugs & Compounds
for ACTR2

Transcripts
for ACTR2

Expression
for ACTR2

Orthologs
for ACTR2

Paralogs
for ACTR2

SNPs/Variants
for ACTR2

Disorders & Mutations
for ACTR2

Medical News
for ACTR2

Publications
for ACTR2

Licensable Technologies
for ACTR2

Services
for ACTR2