Aliases for ACTR1B Gene
External Ids for ACTR1B Gene
Previous Symbols for ACTR1B Gene
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008]
GeneCards Summary for ACTR1B Gene
ACTR1B (ARP1 Actin-Related Protein 1 Homolog B, Centractin Beta (Yeast)) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and MHC class II antigen presentation. An important paralog of this gene is ACTB.
UniProtKB/Swiss-Prot for ACTR1B Gene
Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome