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ACTR10 Gene

protein-coding   GIFtS: 53
GCID: GC14P058666

Actin-Related Protein 10 Homolog (S. Cerevisiae)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Actin-Related Protein 10 Homolog (S. Cerevisiae)1 2     HARP112
Actin-Related Protein 112 3     Actin-Related Protein 102
ACTR112 3     ARP113
Arp112     hARP113

External Ids:    HGNC: 173721   Entrez Gene: 558602   Ensembl: ENSG000001319667   UniProtKB: Q9NZ323   

Export aliases for ACTR10 gene to outside databases

Previous GC identifers: GC14P052462 GC14P056656 GC14P057736 GC14P038835


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ACTR10 Gene:
ACTR10 (actin-related protein 10 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with ACTR10 include intrahepatic cholangiocarcinoma, and cholangiocarcinoma.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000014.9  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the ACTR10 gene promoter:
         HNF-4alpha2   RORalpha2   Evi-1   RORalpha1   E2F-1   E2F   FOXJ2 (long isoform)   COMP1   FOXJ2   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidACTR10 promoter sequence
   Search Chromatin IP Primers for ACTR10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ACTR10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q23.1   Ensembl cytogenetic band:  14q23.1   HGNC cytogenetic band: 14q22.3

ACTR10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACTR10 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P058666:  view genomic region     (about GC identifiers)

Start:
58,666,798 bp from pter      End:
58,702,354 bp from pter
Size:
35,557 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ARP10_HUMAN, Q9NZ32 (See protein sequence)
Recommended Name: Actin-related protein 10  
Size: 417 amino acids; 46307 Da
Secondary accessions: Q9H9Y5 Q9NWY2

Explore the universe of human proteins at neXtProt for ACTR10: NX_Q9NZ32

Explore proteomics data for ACTR10 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys26, Lys44, Lys375
  • Modification sites at PhosphoSitePlus

  • See ACTR10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060947.1  
    ENSEMBL proteins: 
     ENSP00000438183   ENSP00000254286   ENSP00000452586   ENSP00000450796   ENSP00000451863  
     ENSP00000452135   ENSP00000477173   ENSP00000451336   ENSP00000451289  

    ACTR10 Human Recombinant Protein Products:

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    Novus Biologicals ACTR10 Protein
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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for ACTR10

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    Abcam antibodies for ACTR10
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    ThermoFisher Antibodies for ACTR10
    LSBio Antibodies in human, mouse, rat for ACTR10

    ACTR10 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for ACTR10
    Cloud-Clone Corp. CLIAs for ACTR10


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR027127 Arp10
     IPR004000 Actin-related

    Graphical View of Domain Structure for InterPro Entry Q9NZ32

    ProtoNet protein and cluster: Q9NZ32

    1 Blocks protein domain: IPB004000 Actin/actin-like

    UniProtKB/Swiss-Prot: ARP10_HUMAN, Q9NZ32
    Similarity: Belongs to the actin family


    ACTR10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    ACTR10 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ACTR10:
     Synthetic lethal with Ras  Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ACTR10
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ACTR10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ACTR10
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ACTR10

    miRNA
    Products:
        
    miRTarBase miRNAs that target ACTR10:
    hsa-mir-30b-5p (MIRT046144)

    Block miRNA regulation of human, mouse, rat ACTR10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ACTR10 (see all 27):
    hsa-miR-495 hsa-let-7d hsa-let-7a-2* hsa-let-7c hsa-miR-374a hsa-miR-340 hsa-miR-3692 hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidACTR10 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ACTR10
    Predesigned siRNA for gene silencing in human, mouse, rat ACTR10

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ACTR10

    Clone
    Products:
         
    OriGene clones in human, mouse for ACTR10 (see all 7)
    OriGene ORF clones in mouse, rat for ACTR10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ACTR10 (NM_018477)
    Sino Biological Human cDNA Clone for ACTR10
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACTR10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACTR10

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ACTR10
    Browse ESI BIO Cell Lines and PureStem Progenitors for ACTR10 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACTR10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ARP10_HUMAN, Q9NZ32: Cytoplasm, cytoskeleton (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton2
    cytosol2
    nucleus2
    peroxisome2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005869dynactin complex IEA--

    ACTR10 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ACTR10 About    
    See pathways by source

    SuperPathContained pathways About
    1Cytoplasmic microtubules
    Cytoplasmic microtubules0.32
    Cytoskeleton remodeling Neurofilaments0.32
    2Cell cycle Spindle assembly and chromosome separation
    Cell cycle Spindle assembly and chromosome separation

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 GeneGo (Thomson Reuters) Pathways for ACTR10
        Cell cycle Spindle assembly and chromosome separation
    Cytoskeleton remodeling Neurofilaments



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ACTR10
    Interactions:

        Search GeneGlobe Interaction Network for ACTR10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ACTR10 (Q9NZ323 ENSP000002542864) via UniProtKB, MINT, STRING, and/or I2D (see all 54)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTA1P681333, ENSP000003556454I2D: score=1 STRING: ENSP00000355645
    ATG101Q9BSB43I2D: score=1 
    PRKAG1P546193I2D: score=1 
    DCTN4ENSP000004149064STRING: ENSP00000414906
    TP53ENSP000002693054STRING: ENSP00000269305
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007018microtubule-based movement IEA--

    ACTR10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ACTR10 (ARP10)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ACTR10 gene: 
    NM_018477.2  

    Unigene Cluster for ACTR10:

    Actin-related protein 10 homolog (S. cerevisiae)
    Hs.509451  [show with all ESTs]
    Unigene Representative Sequence: NM_018477
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000545307 ENST00000254286(uc001xdf.3 uc010trp.2 uc010apc.3)
    ENST00000555229 ENST00000555337 ENST00000556748 ENST00000556312 ENST00000556243
    ENST00000554402 ENST00000556694 ENST00000557711(uc021rtr.1) ENST00000557583
    ENST00000554790 ENST00000556449 ENST00000555965 ENST00000553907 ENST00000554642

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ACTR10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ACTR10 (see all 27):
    hsa-miR-495 hsa-let-7d hsa-let-7a-2* hsa-let-7c hsa-miR-374a hsa-miR-340 hsa-miR-3692 hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidACTR10 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ACTR10
    Predesigned siRNA for gene silencing in human, mouse, rat ACTR10
    Clone
    Products:
         
    OriGene clones in human, mouse for ACTR10 (see all 7)
    OriGene ORF clones in mouse, rat for ACTR10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ACTR10 (NM_018477)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACTR10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACTR10
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ACTR10
    OriGene qSTAR qPCR primer pairs in human, mouse for ACTR10
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ACTR10
      QuantiTect SYBR Green Assays in human, mouse, rat ACTR10
      QuantiFast Probe-based Assays in human, mouse, rat ACTR10

    Additional mRNA sequence: 

    AF220190.1 AK000544.1 AK022248.1 AK022534.1 AK222624.1 AK222702.1 AK315537.1 BC005208.1 
    BC011997.1 BX161491.1 BX248282.1 

    Selected DOTS entries (see all 42):

    DT.95134533  DT.95134599  DT.100880717  DT.92443761  DT.95242098  DT.100880723  DT.120766522  DT.100756995 
    DT.100880722  DT.100880719  DT.87015856  DT.92443764  DT.40224817  DT.100880720  DT.120766576  DT.120766578 
    DT.92443779  DT.100735190  DT.100842302  DT.100880718  DT.100880735  DT.101961825  DT.120766772  DT.87015855 

    Selected AceView cDNA sequences (see all 429):

    CA306298 BU181264 AA448442 BQ637573 BX366738 AA284960 CR621042 AA890331 
    BM968311 CD629294 BM693273 AU123200 BM696607 BQ718771 BM976050 AI143201 
    CA418585 CR600466 F34780 W37097 CB125811 CR617931 BU683016 BX388481 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ACTR10    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                  -                     
    SP2:                                                                        
    SP3:                                      -           -                     
    SP4:                                                                        
    SP5:                                                                        


    ECgene alternative splicing isoforms for ACTR10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ACTR10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCCTAGATT
    ACTR10 Expression
    About this image


    ACTR10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Eye (Sensory Organs)
             Lens
    ACTR10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ACTR10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.509451
        Custom PCR Arrays for ACTR10
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ACTR10
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    QuantiFast Probe-based Assays in human, mouse, rat ACTR10
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACTR10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ACTR10 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Actr101 , 5 ARP10 actin-related protein 10 homolog (S. cerevisiae)5
    ARP10 actin-related protein 101
    90.65(n)1
    95.2(a)1
      12 (29.39 cM)5
    564441  NM_019785.21  NP_062759.21 
     709378575 
    chicken
    (Gallus gallus)
    Aves ACTR101 actin-related protein 10 homolog (S. cerevisiae) 79.3(n)
    87.05(a)
      423543  NM_001006492.1  NP_001006492.1 
    lizard
    (Anolis carolinensis)
    Reptilia ACTR106
    actin-related protein 10 homolog (S. cerevisiae)
    88(a)
    1 ↔ 1
    GL343325.1(389582-403791)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.228022 Xenopus laevis transcribed sequence with moderate similarity more 78.14(n)    CA974739.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc556352 similar to ARP10 actin-related protein 10 homolog more 73.3(n)   393139  BC045412.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Arp101 Actin-related protein 10 49.68(n)
    43.63(a)
      32969  NM_134494.2  NP_608338.1 
    worm
    (Caenorhabditis elegans)
    Secernentea arp-116
    Protein ARP-11 (arp-11) mRNA, complete cds
    23(a)
    1 ↔ 1
    IV(7900200-7902271) WBGene00016793


    ENSEMBL Gene Tree for ACTR10 (if available)
    TreeFam Gene Tree for ACTR10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ACTR10 gene
    Selected SIMAP similar genes for ACTR10 using alignment to 10 protein entries:     ARP10_HUMAN (see all proteins) (see all similar genes):
    MST132    SLMO1    NDC80    RBMS2    CEP95    EEF1E1
    MRPL45    NLN    TNNT1    ZNF28    COQ5    TMX3
    LSM12    SEC14L3    DPP9    UBE2V2    AAMDC    NLRC5

    ACTR10 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ACTR10 (see all 687)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs758355951,2
    --58664909(+) AAAAAA/GAAAAA 1 -- us2k10--------
    rs2012344591,2
    C--58664909(+) AAAAA-/AGACAA 1 -- us2k10--------
    rs1145293331,2
    C,F--58664952(+) GCCTTC/AAAAGA 1 -- us2k11Minor allele frequency- A:0.04WA 118
    rs1153234401,2
    C,F--58664962(+) AGGGCA/CTGACC 1 -- us2k11Minor allele frequency- C:0.04WA 118
    rs1166934511,2
    C,F--58665088(+) ACAAAT/AACAGC 1 -- us2k11Minor allele frequency- A:0.09WA 118
    rs1477651021,2
    --58665116(+) AAACAG/TAGAAT 1 -- us2k10--------
    rs1865970821,2
    --58665136(+) CAAACC/TTCATC 1 -- us2k10--------
    rs1896640131,2
    --58665183(+) CCTTAC/TAAATA 1 -- us2k10--------
    rs619759151,2
    C,F--58665283(+) GAACTC/TAAGTA 1 -- us2k12Minor allele frequency- T:0.24NA 122
    rs1119906761,2
    C,F--58665407(+) AATTTG/CCTTTC 1 -- us2k12Minor allele frequency- C:0.03CSA WA 120

    HapMap Linkage Disequilibrium report for ACTR10 (58666798 - 58702354 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ACTR10:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv901985CNV Loss21882294
    nsv901986CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ACTR10
    DNA2.0 Custom Variant and Variant Library Synthesis for ACTR10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    4 diseases for ACTR10:    
    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    malaria    cerebritis


    ACTR10 for disorders           About GeneDecksing


    Export disorders for ACTR10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for ACTR10 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with ACTR10)
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    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1. (PubMed id 12857853)1, 3 Eckley D.M. and Schroer T.A. (Mol. Biol. Cell 2003)
    4. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    6. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    7. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55860 HGNC: 17372 AceView: ACTR10 Ensembl:ENSG00000131966 euGenes: HUgn55860
    ECgene: ACTR10 H-InvDB: ACTR10

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ACTR10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ACTR10 gene:
    Search GeneIP for patents involving ACTR10

    GeneCards and IP:
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