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Aliases for ACTR10 Gene

Aliases for ACTR10 Gene

  • Actin-Related Protein 10 Homolog 2 3
  • Actin-Related Protein 10 Homolog (S. Cerevisiae) 2 5
  • Actin-Related Protein 11 3 4
  • HARP11 3 4
  • ACTR11 3 4
  • Arp11 3 4
  • Arp10 3

External Ids for ACTR10 Gene

Previous GeneCards Identifiers for ACTR10 Gene

  • GC14P052462
  • GC14P056656
  • GC14P057736
  • GC14P058666
  • GC14P038835

Summaries for ACTR10 Gene

GeneCards Summary for ACTR10 Gene

ACTR10 (Actin-Related Protein 10 Homolog) is a Protein Coding gene. Among its related pathways are Cell cycle_Spindle assembly and chromosome separation and Cytoskeleton remodeling Neurofilaments.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACTR10 Gene

Genomics for ACTR10 Gene

Regulatory Elements for ACTR10 Gene

Enhancers for ACTR10 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ACTR10 on UCSC Golden Path with GeneCards custom track

Promoters for ACTR10 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ACTR10 on UCSC Golden Path with GeneCards custom track

Genomic Location for ACTR10 Gene

Chromosome:
14
Start:
58,200,080 bp from pter
End:
58,235,636 bp from pter
Size:
35,557 bases
Orientation:
Plus strand

Genomic View for ACTR10 Gene

Genes around ACTR10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ACTR10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ACTR10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ACTR10 Gene

Proteins for ACTR10 Gene

  • Protein details for ACTR10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NZ32-ARP10_HUMAN
    Recommended name:
    Actin-related protein 10
    Protein Accession:
    Q9NZ32
    Secondary Accessions:
    • Q9H9Y5
    • Q9NWY2

    Protein attributes for ACTR10 Gene

    Size:
    417 amino acids
    Molecular mass:
    46307 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ACTR10 Gene

Proteomics data for ACTR10 Gene at MOPED

Post-translational modifications for ACTR10 Gene

  • Ubiquitination at Lys 26, Lys 44, and Lys 375
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ACTR10 Gene

Domains & Families for ACTR10 Gene

Protein Domains for ACTR10 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for ACTR10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9NZ32

UniProtKB/Swiss-Prot:

ARP10_HUMAN :
  • Belongs to the actin family.
Family:
  • Belongs to the actin family.
genes like me logo Genes that share domains with ACTR10: view

No data available for Gene Families for ACTR10 Gene

Function for ACTR10 Gene

genes like me logo Genes that share phenotypes with ACTR10: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ACTR10 Gene

Localization for ACTR10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ACTR10 Gene

Cytoplasm, cytoskeleton.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ACTR10 Gene COMPARTMENTS Subcellular localization image for ACTR10 gene
Compartment Confidence
cytoskeleton 3
cytosol 2
nucleus 2
peroxisome 2

Gene Ontology (GO) - Cellular Components for ACTR10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with ACTR10: view

Pathways & Interactions for ACTR10 Gene

genes like me logo Genes that share pathways with ACTR10: view

Pathways by source for ACTR10 Gene

Gene Ontology (GO) - Biological Process for ACTR10 Gene

None

No data available for SIGNOR curated interactions for ACTR10 Gene

Drugs & Compounds for ACTR10 Gene

No Compound Related Data Available

Transcripts for ACTR10 Gene

Unigene Clusters for ACTR10 Gene

Actin-related protein 10 homolog (S. cerevisiae):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ACTR10 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
SP1: -
SP2:
SP3: - -
SP4:
SP5:

Relevant External Links for ACTR10 Gene

GeneLoc Exon Structure for
ACTR10
ECgene alternative splicing isoforms for
ACTR10

Expression for ACTR10 Gene

mRNA expression in normal human tissues for ACTR10 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ACTR10 Gene

This gene is overexpressed in Lavage (16.0) and Peripheral blood mononuclear cells (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ACTR10 Gene



SOURCE GeneReport for Unigene cluster for ACTR10 Gene Hs.509451

genes like me logo Genes that share expression patterns with ACTR10: view

Protein tissue co-expression partners for ACTR10 Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ACTR10 Gene

Orthologs for ACTR10 Gene

This gene was present in the common ancestor of animals.

Orthologs for ACTR10 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ACTR10 35
  • 92.57 (n)
  • 95.92 (a)
ACTR10 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ACTR10 35
  • 92.01 (n)
  • 96.4 (a)
ACTR10 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Actr10 35
  • 90.65 (n)
  • 95.2 (a)
Actr10 16
Actr10 36
  • 95 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ACTR10 35
  • 99.85 (n)
  • 100 (a)
ACTR10 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Actr10 35
  • 89.85 (n)
  • 94.96 (a)
oppossum
(Monodelphis domestica)
Mammalia ACTR10 36
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ACTR10 36
  • 89 (a)
OneToOne
chicken
(Gallus gallus)
Aves ACTR10 35
  • 79.3 (n)
  • 87.05 (a)
-- 36
  • 85 (a)
OneToMany
ACTR10 36
  • 87 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia ACTR10 36
  • 88 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia actr10 35
  • 76.58 (n)
  • 84.17 (a)
Str.5840 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.22802 35
zebrafish
(Danio rerio)
Actinopterygii actr10 35
  • 67.47 (n)
  • 75.42 (a)
zgc55635 35
actr10 36
  • 75 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012077 35
  • 48.77 (n)
  • 43.05 (a)
fruit fly
(Drosophila melanogaster)
Insecta Arp10 35
  • 49.68 (n)
  • 43.63 (a)
Arp11 36
  • 40 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea arp-11 36
  • 23 (a)
OneToOne
Species with no ortholog for ACTR10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ACTR10 Gene

ENSEMBL:
Gene Tree for ACTR10 (if available)
TreeFam:
Gene Tree for ACTR10 (if available)

Paralogs for ACTR10 Gene

genes like me logo Genes that share paralogs with ACTR10: view

No data available for Paralogs for ACTR10 Gene

Variants for ACTR10 Gene

Sequence variations from dbSNP and Humsavar for ACTR10 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs12499 -- 58,232,213(-) AAATG(A/T)CTTAG reference, missense
rs13236 -- 58,234,591(-) GGTTA(A/G)ATATT utr-variant-3-prime
rs8004938 -- 58,215,977(+) tcttt(C/T)ttttt intron-variant
rs8020516 -- 58,212,084(+) TCAGC(A/T)AAGCT intron-variant
rs3063562 -- 58,231,079(+) GACAG(-/AA/AG)TGTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ACTR10 Gene

Variant ID Type Subtype PubMed ID
nsv901985 CNV Loss 21882294
nsv901986 CNV Loss 21882294

Variation tolerance for ACTR10 Gene

Residual Variation Intolerance Score: 37.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.04; 21.22% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ACTR10 Gene

Disorders for ACTR10 Gene

Relevant External Links for ACTR10

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ACTR10

No disorders were found for ACTR10 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ACTR10 Gene

Publications for ACTR10 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1. (PMID: 12857853) Eckley D.M. … Schroer T.A. (Mol. Biol. Cell 2003) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3

Products for ACTR10 Gene

Sources for ACTR10 Gene

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