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ACTN3 Gene

protein-coding GIFtS: 63

GC11P066070

actinin, alpha 3
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
MGC117002 ^²
MGC117005 ^²

Descriptions
Alpha-actinin skeletal muscle isoform 3 ^³
F-actin cross-linking protein ^³
actinin, alpha 3 ^²

External Ids
HGNC: 165¹
Entrez Gene: 89²
UniProtKB: Q08043³
Ensembl: ENSG00000204633⁷

Search outside databases for aliases for ACTN3 gene

Previous GC identifers: GC11P068848 GC11P067996 GC11P066564 GC11P066089

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ACTN3:

Alpha-actinin is an actin-binding protein with multiple roles in different cell types. This gene

expression is limited to skeletal muscle. It is localized to the Z-disc and analogous dense

bodies, where it helps to anchor the myofibrillar actin filaments [provided by RefSeq]

UniProtKB/Swiss-Prot: ACTN3_HUMAN, Q08043

Function: F-actin cross-linking protein which is thought to anchor actin to a variety of

intracellular structures. This is a bundling protein

Gene Wiki entry for ACTN3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ACTN3 gene

Entrez Gene cytogenetic band: 11q13.1 Ensembl cytogenetic band: 11q13.1 HGNC cytogenetic band: 11q13-q14

ACTN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11P066070: (about GC identifiers)

Start:	66,070,967 bp from pter
End:	66,087,373 bp from pter
Size:	16,407 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000011.8 NT_033903.7

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ACTN3_HUMAN, Q08043 (See protein sequence)

Recommended Name: Alpha-actinin-3

Size: 901 amino acids; 103241 Da

Subunit: Homodimer; antiparallel. Also forms heterodimers with ACTN2. Interacts with MYOZ1

Sequence caution: Sequence=AP002748; Type=Miscellaneous discrepancy; Note=According to the human

genome assembly there is a stop codon in position 577 which is only found in 18% of the world

population;

PDB structure from and Proteopedia :

1TJT (3D)

1WKU (3D)

Secondary accessions: A6NP77 Q4KKV2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_001095.1

ENSEMBL proteins:

ENSP00000366035

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
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	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ACTN3)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005884	actin filament	TAS	1339456
GO:0005925	focal adhesion	IMP	16807302
GO:0031143	pseudopodium	TAS	1629252

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Antibodies for ACTN3:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ACTN3
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (ACTN3), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Novus Biologicals Antibody for ACTN3

Assays for ACTN3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q08043

ProtoNet protein and cluster: Q08043

3 Blocks protein families:

IPB001589 Actin-binding

IPB001715 Calponin-like actin-binding

IPB002017 Spectrin repeat

UniProtKB/Swiss-Prot: ACTN3_HUMAN, Q08043

Similarity: Belongs to the alpha-actinin family

Similarity: Contains 1 actin-binding domain

Similarity: Contains 2 CH (calponin-homology) domains

Similarity: Contains 2 EF-hand domains

Similarity: Contains 4 spectrin repeats

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ACTN3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ACTN3)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001104

Applied Biosystems Silencer® siRNAs for ACTN3

Sigma-Aldrich siRNA for ACTN3

Sigma-Aldrich shRNA for ACTN3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001104
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001104
untagged cDNA clone in CMV expression vector: NM_001104

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001104

UniProtKB/Swiss-Prot: ACTN3_HUMAN, Q08043

Function: F-actin cross-linking protein which is thought to anchor actin to a variety of

intracellular structures. This is a bundling protein

Genatlas biochemistry entry for ACTN3:

actinin,alpha 3,actin filament cross-linking,calcium insensitive,expressed in skeletal muscle,type

2 (fast) fibres

2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Actn3):

homeostasis/metabolism

muscle

5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003779	actin binding	IEA	--
GO:0005178	integrin binding	TAS	8104223
GO:0005509	calcium ion binding	IEA	--
GO:0005515	protein binding	IPI	11171996
GO:0008307	structural constituent of muscle	TAS	1339456

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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5 Sigma-Aldrich "Your Favorite Gene" Pathways for ACTN3 (Your Favorite Gene powered by Ingenuity)

Leukocyte Extravasation Signaling
Germ Cell-Sertoli Cell Junction Signaling
Actin Cytoskeleton Signaling
VEGF Signaling
Integrin Signaling

GeneDecks ACTN3 for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for ACTN3

1 Interacting protein for ACTN3 (Q08043²) via UniProtKB, MINT, and/or STRING
Interactant Interaction Details
GeneCard External ID(s)
-- Q93003² MINT-18039 MINT-18038 MINT-18037
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2 Gene Ontology (GO) biological process terms (links to tree view):
GO ID Qualified GO term Evidence PubMed IDs
GO:0042981 regulation of apoptosis NAS 16807302
GO:0048041 focal adhesion formation IMP 16807302
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ACTN3
1 Novoseek chemical compound relationship for ACTN3 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
calcium	0.00	2	1339456 (1)

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(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ACTN3)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ACTN3)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001104

Sigma-Aldrich siRNA for ACTN3

Sigma-Aldrich shRNA for ACTN3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001104

REFSEQ mRNAs for ACTN3 gene:

NM_001104.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001104

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001104
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001104
                                 untagged cDNA clone in CMV expression vector: NM_001104

Additional cDNA sequence:

AK125851.1 AK303044.1 AK313556.1 BC096323.2 BC099647.3 BC099648.1 BC099649.3 M86407.1

6 DOTS entries:

DT.309857 DT.120710797 DT.91926044 DT.120710710 DT.40245906 DT.75155085

24/33 AceView cDNA sequences (see all 33 ):

F32349 AA196000 T29827 M86407 AJ571886 BQ575174 AA196115 F18712

AI224547 F21130 AJ346025 NM_001104 F33937 AJ346065 AL598669 AK125851

AL598649 F17757 CD610740 CD610746 CD610738 CD610745 BX117834 CD610744

highest scoring ESTs for ACTN3:

M86407 AA196000 AA196115 AJ346025 AJ346065 AJ571886 AJ574558 AW951618 BQ575174 F17757

Unigene Cluster for ACTN3:

Actinin, alpha 3

Hs.654432 [show with all ESTs]

Unigene Representative Sequence: AK125851

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000376839

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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ACTN3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ACTN3

¹ / ² / ³

3 probe-sets matching ACTN3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34499_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	M86407	1.00	1.00	1.00	1
206891_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001104	0.60	1.00	0.82	1
206891_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks ACTN3 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.654432
Expression variation in blood from EXPOLDB for ACTN3
UniProtKB/Swiss-Prot: ACTN3_HUMAN, Q08043
Tissue specificity: Expressed only in a subset of type 2 skeletal muscle fibers

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ACTN3 gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ACTN3¹	--	actinin, alpha 3	92.12(n) 97.11(a)	483707 XM_540828.2 XP_540828.2
cow (Bos taurus)	ACTN3¹	--	actinin, alpha 3	92.19(n) 97.11(a)	539375 NM_001076157.1 NP_001069625.1
rat (Rattus norvegicus)	Actn3¹	--	actinin alpha 3	89.56(n) 97.44(a)	171009 NM_133424.1 NP_596915.1
mouse (Mus musculus)	Actn3^{1, 5}	19 (3.00 cM)⁵	actinin alpha 3^{1, 5}	89.52(n)¹ 97.56(a)¹	11474¹ NM_013456.1¹ NP_038484.1¹ AF093775⁵ AK134757⁵ (see all 8)
zebrafish (Danio rerio)	Dr.5066²	--	Danio rerio alpha-actinin mRNA, complete cds	80.35(n)	AF524840.1

About this table Species with no ortholog for ACTN3

ENSEMBL Gene Tree for ACTN3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ACTN3 gene

ACTN2² ACTN4² ACTN1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

UniProtKB/Swiss-Prot: ACTN3_HUMAN, Q08043

Polymorphism: About 18% of the world population lack a functional ACTN3 due to a stop codon

polymorphism at position 577. The absence of a functional ACTN3 expression is not correlated with

a disease state

10/95 NCBI SNPs in ACTN3 are shown (see all 95 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 49)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs540874^1,2	A,C,F,H,O	66086308(-)	`CATTCC/TGCTTC`	1	R/Q	mis¹		20	NA MN EA EU WA	3090
	rs1815739^1,2	A,C,F,H	66084671(+)	`CTGACC/TGAGAG`	1	R/X	non¹ ese³		5	EU EA WA MN	462
	rs618838^1,2	A,C,F,H	66085295(+)	`CCAGCC/TGTGAC`	1	R/C	mis¹ ese³		9	MN EA EU WA NA	2178
	rs1671064^1,2	C,F,H,O	66084249(-)	`GCAGCT/CGGTCA`	1	R/Q	mis¹ ese³		14	MN NA EU EA WA	1336
--	rs2229456^1,2	C,F,H	66085317(+)	`GGAGGA/CGCTGG`	1	E/A	mis¹		13	MN EU EA WA NA	1080
	rs2229455^1,2	C,F	66084631(+)	`CTGACA/GGCGCA`	1	T/T	syn¹ ese³		2	MN NA	100
	rs677488^1,2	A,C,F,H	66081338(-)	`CTTGGA/GGTTAG`	1	--	int¹		14	EA NA EU WA	1070
--	rs597626^1,2	A,C,F,H	66073133(-)	`GCAGGG/AGCCAG`	1	--	int¹		5	MN EU EA WA	594
	rs509556^1,2	A,C,F,H	66082938(-)	`AACAAC/TGAATG`	1	--	int¹		13	EA NA EU WA	2624
	rs1791690^1,2	A,C,F,H	66074399(+)	`GTGTCG/ATGTCA`	1	--	int¹		13	MN EU EA WA NA	1293

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HapMap Linkage Disequilibrium images for ACTN3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 102574

1 Novoseek disease relationship for ACTN3 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
muscular dystrophies	35.63	3	9309713 (1), 8887951 (1)

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Human Gene Mutation Database: ACTN3
Genetic Association Database: ACTN3
Human Genome Epidemiology Navigator: ACTN3 (28 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/60 PubMed articles for ACTN3 gene (see all 60 ):

Cloning and characterization of two human skeletal muscle alpha- actinin genes located on chromosomes 1 and 11. (PubMed id 1339456)^{1, 2, 3, 4} Beggs A.H....Kunkel L.M. (1992)
Differential expression of the actin-binding proteins, alpha-actinin- 2 and -3, in different species: implications for the evolution of functional redundancy. (PubMed id 11440986)^{1, 3, 4} Mills M.... North K.N. (2001)
ACTN3 genotype is associated with increases in muscle strength in response to resistance training in women. (PubMed id 15718405)^{1, 3, 6} Clarkson P.M....Hoffman E.P. (2005)
ACTN3 genotype is associated with human elite athletic performance. (PubMed id 12879365)^{1, 3, 6} Yang N....North K. (2003)
ACTN3 and MLCK genotype associations with exertional muscle damage. (PubMed id 15817725)^{1, 3, 6} Clarkson P.M....Devaney J.M. (2005)
A common nonsense mutation results in alpha-actinin-3 deficiency in the general population. (PubMed id 10192379)^{1, 3, 4} North K.N....Beggs A.H. (1999)
The crystal structure of the actin binding domain from alpha-actinin in its closed conformation: structural insight into phospholipid regulation of alpha-actinin. (PubMed id 15808860)^{1, 3, 4} Franzot G.... Djinovic Carugo K. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Myozenin: an alpha-actinin- and gamma-filamin-binding protein of skeletal muscle Z lines. (PubMed id 11171996)^{3, 4} Takada F.... Beggs A.H. (2001)
Strength, power, fiber types, and mRNA expression in trained men and women with different ACTN3 R577X genotypes. (PubMed id 19150855)^{1, 3} Norman B....Tesch P.A. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 89	HGNC: 165	AceView: ACTN3	Ensembl:ENSG00000204633	euGenes: HUgn89
ECgene: ACTN3	H-InvDB: ACTN3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for ACTN3
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for ACTN3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ACTN3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ACTN3		Antibodies for ACTN3
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ACTN3		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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ACTN3 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for ACTN3

Summaries
for ACTN3

Genomic Location
for ACTN3

Proteins
for ACTN3

Protein Domains/
Families
for ACTN3

Gene Function
for ACTN3

Pathways & Interactions
for ACTN3

Drugs & Compounds
for ACTN3

Transcripts
for ACTN3

Expression
for ACTN3

Orthologs
for ACTN3

Paralogs
for ACTN3

SNPs/Variants
for ACTN3

Disorders & Mutations
for ACTN3

Medical News
for ACTN3

Publications
for ACTN3

Search for ACTN3

Genome Databases showing ACTN3

Other Databases showing ACTN3

Specialized Databases showing ACTN3

Licensable Technologies
for ACTN3

Services
for ACTN3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ACTN3 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor ACTN3

Summariesfor ACTN3

Genomic Locationfor ACTN3

Proteinsfor ACTN3

Protein Domains/Familiesfor ACTN3

Gene Functionfor ACTN3

Pathways & Interactionsfor ACTN3

Drugs & Compoundsfor ACTN3

Transcriptsfor ACTN3

Expression for ACTN3

Orthologsfor ACTN3

Paralogsfor ACTN3

SNPs/Variantsfor ACTN3

Disorders & Mutationsfor ACTN3

Medical Newsfor ACTN3

Publicationsfor ACTN3

Search for ACTN3

Genome Databases showing ACTN3

Other Databases showing ACTN3

Specialized Databases showing ACTN3

Licensable Technologiesfor ACTN3

Servicesfor ACTN3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ACTN3

Summaries
for ACTN3

Genomic Location
for ACTN3

Proteins
for ACTN3

Protein Domains/
Families
for ACTN3

Gene Function
for ACTN3

Pathways & Interactions
for ACTN3

Drugs & Compounds
for ACTN3

Transcripts
for ACTN3

Expression
for ACTN3

Orthologs
for ACTN3

Paralogs
for ACTN3

SNPs/Variants
for ACTN3

Disorders & Mutations
for ACTN3

Medical News
for ACTN3

Publications
for ACTN3

Licensable Technologies
for ACTN3

Services
for ACTN3