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Aliases for ACTL9 Gene

Aliases for ACTL9 Gene

  • Actin-Like 9 2 3
  • Actin-Like Protein 9 3
  • ACTL7C 4
  • HSD21 3

External Ids for ACTL9 Gene

Summaries for ACTL9 Gene

GeneCards Summary for ACTL9 Gene

ACTL9 (Actin-Like 9) is a Protein Coding gene. Diseases associated with ACTL9 include colorectal cancer. An important paralog of this gene is ACTL7B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACTL9 Gene

Genomics for ACTL9 Gene

Genomic Location for ACTL9 Gene

Start:
8,697,397 bp from pter
End:
8,698,830 bp from pter
Size:
1,434 bases
Orientation:
Minus strand

Genomic View for ACTL9 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ACTL9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ACTL9 Gene

No data available for Regulatory Elements for ACTL9 Gene

Proteins for ACTL9 Gene

  • Protein details for ACTL9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TC94-ACTL9_HUMAN
    Recommended name:
    Actin-like protein 9
    Protein Accession:
    Q8TC94
    Secondary Accessions:
    • A8K893
    • Q6X960

    Protein attributes for ACTL9 Gene

    Size:
    416 amino acids
    Molecular mass:
    45627 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ACTL9 Gene

Proteomics data for ACTL9 Gene at MOPED

Post-translational modifications for ACTL9 Gene

No Post-translational modifications

Other Protein References for ACTL9 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ACTL9 Gene

Domains for ACTL9 Gene

Protein Domains for ACTL9 Gene

UniProtKB/Swiss-Prot:

ACTL9_HUMAN
Family:
  • Belongs to the actin family.:
    • Q8TC94
genes like me logo Genes that share domains with ACTL9: view

No data available for Gene Families for ACTL9 Gene

Function for ACTL9 Gene

Phenotypes for ACTL9 Gene

genes like me logo Genes that share phenotypes with ACTL9: view

miRNA for ACTL9 Gene

miRTarBase miRNAs that target ACTL9

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for ACTL9 Gene

Localization for ACTL9 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ACTL9 Gene

Cytoplasm, cytoskeleton.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ACTL9 Gene COMPARTMENTS Subcellular localization image for ACTL9 gene
Compartment Confidence
cytosol 3
cytoskeleton 2
nucleus 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for ACTL9 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005856 cytoskeleton IEA --
genes like me logo Genes that share ontologies with ACTL9: view

Pathways for ACTL9 Gene

SuperPathways for ACTL9 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ACTL9 Gene

None

No data available for Pathways by source for ACTL9 Gene

Transcripts for ACTL9 Gene

mRNA/cDNA for ACTL9 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(19) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ACTL9 Gene

Actin-like 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ACTL9 Gene

No ASD Table

Relevant External Links for ACTL9 Gene

GeneLoc Exon Structure for
ACTL9
ECgene alternative splicing isoforms for
ACTL9

Expression for ACTL9 Gene

mRNA expression in normal human tissues for ACTL9 Gene

mRNA differential expression in normal tissues according to GTEx for ACTL9 Gene

This gene is overexpressed in Testis (52.6).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ACTL9 Gene

SOURCE GeneReport for Unigene cluster for ACTL9 Gene Hs.209206

genes like me logo Genes that share expressions with ACTL9: view

Orthologs for ACTL9 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ACTL9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ACTL9 36
  • 99.52 (n)
  • 99.04 (a)
ACTL9 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ACTL9 36
  • 83.41 (n)
  • 81.49 (a)
ACTL9 37
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ACTL9 36
  • 83.81 (n)
  • 81.25 (a)
ACTL9 37
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Actl9 36
  • 76.09 (n)
  • 80.05 (a)
Actl9 16
Actl9 37
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ACTL9 37
  • 63 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Actl9 36
  • 75.9 (n)
  • 79.35 (a)
chicken
(Gallus gallus)
Aves ACTL9 36
  • 56.59 (n)
  • 44.23 (a)
ACTL9 37
  • 43 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ACTL9 37
  • 54 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ARP2 37
  • 31 (a)
OneToMany
Species with no ortholog for ACTL9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ACTL9 Gene

ENSEMBL:
Gene Tree for ACTL9 (if available)
TreeFam:
Gene Tree for ACTL9 (if available)

Paralogs for ACTL9 Gene

Paralogs for ACTL9 Gene

Selected SIMAP similar genes for ACTL9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ACTL9: view

Variants for ACTL9 Gene

Sequence variations from dbSNP and Humsavar for ACTL9 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs975281 -- 8,700,806(-) tactt(G/T)ggagg upstream-variant-2KB
rs975282 -- 8,700,739(-) attgc(A/G)ccact upstream-variant-2KB
rs2340550 - 8,698,592(+) CGGGG(A/G)AGTCC reference, missense
rs4804079 - 8,698,023(+) CAGGT(G/T)GTTGC reference, missense
rs7254503 -- 8,700,228(+) GATAC(A/G)AGAAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ACTL9 Gene

Variant ID Type Subtype PubMed ID
nsv469747 CNV Complex 16826518
nsv471705 CNV Gain+Loss 15918152
nsv833735 CNV Gain+Loss 17160897
nsv469648 CNV Complex 16826518

Relevant External Links for ACTL9 Gene

HapMap Linkage Disequilibrium report
ACTL9

Disorders for ACTL9 Gene

(1) MalaCards Diseases for ACTL9 Gene

Search for ACTL9 Gene in MalaCards »
genes like me logo Genes that share disorders with ACTL9: view

No data available for UniProtKB/Swiss-Prot for ACTL9 Gene

Publications for ACTL9 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis. (PMID: 22197932) Paternoster L. … Weidinger S. (Nat. Genet. 2012) 3
  3. Association of KIF3A, but not OVOL1 and ACTL9, with atopic eczema in Italian patients. (PMID: 23278845) Lepre T. … Giardina E. (Br. J. Dermatol. 2013) 3
  4. Large-scale analysis of lysine SUMOylation by SUMO remnant immunoaffinity profiling. (PMID: 25391492) Lamoliatte F. … Thibault P. (Nat Commun 2014) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for ACTL9 Gene

Sources for ACTL9 Gene

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