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Aliases for ACTL10 Gene

Aliases for ACTL10 Gene

  • Actin Like 10 2 3 5
  • C20orf134 3 4
  • Chromosome 20 Open Reading Frame 134 2
  • Actin-Like 10 3
  • DJ63M2.2 3

External Ids for ACTL10 Gene

Previous HGNC Symbols for ACTL10 Gene

  • C20orf134

Previous GeneCards Identifiers for ACTL10 Gene

  • GC20P032255

Summaries for ACTL10 Gene

GeneCards Summary for ACTL10 Gene

ACTL10 (Actin Like 10) is a Protein Coding gene. An important paralog of this gene is ACTR2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACTL10 Gene

Genomics for ACTL10 Gene

Regulatory Elements for ACTL10 Gene

Promoters for ACTL10 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ACTL10 on UCSC Golden Path with GeneCards custom track

Genomic Location for ACTL10 Gene

Chromosome:
20
Start:
33,666,498 bp from pter
End:
33,668,525 bp from pter
Size:
2,028 bases
Orientation:
Plus strand

Genomic View for ACTL10 Gene

Genes around ACTL10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ACTL10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ACTL10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ACTL10 Gene

Proteins for ACTL10 Gene

  • Protein details for ACTL10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JWF8-ACL10_HUMAN
    Recommended name:
    Actin-like protein 10
    Protein Accession:
    Q5JWF8
    Secondary Accessions:
    • B9EH76

    Protein attributes for ACTL10 Gene

    Size:
    245 amino acids
    Molecular mass:
    26751 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ACTL10 Gene

Proteomics data for ACTL10 Gene at MOPED

Post-translational modifications for ACTL10 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ACTL10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ACTL10 Gene

Domains & Families for ACTL10 Gene

Protein Domains for ACTL10 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ACTL10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5JWF8

UniProtKB/Swiss-Prot:

ACL10_HUMAN :
  • Belongs to the actin family.
Family:
  • Belongs to the actin family.
genes like me logo Genes that share domains with ACTL10: view

No data available for Gene Families for ACTL10 Gene

Function for ACTL10 Gene

Phenotypes for ACTL10 Gene

genes like me logo Genes that share phenotypes with ACTL10: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ACTL10 Gene

Localization for ACTL10 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ACTL10 Gene COMPARTMENTS Subcellular localization image for ACTL10 gene
Compartment Confidence
extracellular 3
cytosol 2
lysosome 1
mitochondrion 1
nucleus 1
vacuole 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ACTL10 Gene

Pathways & Interactions for ACTL10 Gene

SuperPathways for ACTL10 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ACTL10 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ACTL10 Gene

Drugs & Compounds for ACTL10 Gene

No Compound Related Data Available

Transcripts for ACTL10 Gene

mRNA/cDNA for ACTL10 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ACTL10 Gene

Actin-like 10:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ACTL10 Gene

No ASD Table

Relevant External Links for ACTL10 Gene

GeneLoc Exon Structure for
ACTL10
ECgene alternative splicing isoforms for
ACTL10

Expression for ACTL10 Gene

mRNA expression in normal human tissues for ACTL10 Gene

Protein differential expression in normal tissues from HIPED for ACTL10 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ACTL10 Gene



SOURCE GeneReport for Unigene cluster for ACTL10 Gene Hs.592151

genes like me logo Genes that share expression patterns with ACTL10: view

Protein tissue co-expression partners for ACTL10 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ACTL10 Gene

Orthologs for ACTL10 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ACTL10 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ACTL10 35
  • 83.13 (n)
  • 79.59 (a)
ACTL10 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Actl10 35
  • 80.27 (n)
  • 77.96 (a)
Actl10 16
Actl10 36
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Actl10 35
  • 81.09 (n)
  • 78.37 (a)
dog
(Canis familiaris)
Mammalia ACTL10 36
  • 49 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ACTL10 36
  • 60 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ACTL10 36
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves ACTL10 36
  • 20 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ARP2 36
  • 19 (a)
OneToMany
Species with no ortholog for ACTL10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ACTL10 Gene

ENSEMBL:
Gene Tree for ACTL10 (if available)
TreeFam:
Gene Tree for ACTL10 (if available)

Paralogs for ACTL10 Gene

Paralogs for ACTL10 Gene

(15) SIMAP similar genes for ACTL10 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ACTL10: view

Variants for ACTL10 Gene

Variation tolerance for ACTL10 Gene

Residual Variation Intolerance Score: 68.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.24; 24.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ACTL10 Gene

HapMap Linkage Disequilibrium report
ACTL10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for ACTL10 Gene

Disorders for ACTL10 Gene

Relevant External Links for ACTL10

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ACTL10

No disorders were found for ACTL10 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ACTL10 Gene

Publications for ACTL10 Gene

  1. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ACTL10 Gene

Sources for ACTL10 Gene

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