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Aliases for ACTB Gene

Aliases for ACTB Gene

  • Actin Beta 2 3 5
  • PS1TP5-Binding Protein 1 3
  • Beta Cytoskeletal Actin 3
  • Actin, Cytoplasmic 1 3
  • Beta-Actin 4
  • PS1TP5BP1 3
  • BRWS1 3

External Ids for ACTB Gene

Previous GeneCards Identifiers for ACTB Gene

  • GC07M005211
  • GC07M005311
  • GC07M005340
  • GC07M005533
  • GC07M005479
  • GC07M005566

Summaries for ACTB Gene

Entrez Gene Summary for ACTB Gene

  • This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008]

GeneCards Summary for ACTB Gene

ACTB (Actin Beta) is a Protein Coding gene. Diseases associated with ACTB include Dystonia, Juvenile-Onset and Baraitser-Winter Syndrome 1. Among its related pathways are EPHA forward signaling and Arrhythmogenic right ventricular cardiomyopathy (ARVC). GO annotations related to this gene include identical protein binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is ACTG1.

UniProtKB/Swiss-Prot for ACTB Gene

  • Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Tocris Summary for ACTB Gene

  • Actin is a ubiquitous globular protein that is one of the most highly-conserved proteins known. It is found in two main states: G-actin is the globular monomeric form, whereas F-actin forms helical polymers. Both G- and F-actin are intrinsically flexible structures.

Gene Wiki entry for ACTB Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACTB Gene

Genomics for ACTB Gene

Regulatory Elements for ACTB Gene

Enhancers for ACTB Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F005687 1.5 FANTOM5 Ensembl ENCODE 13.7 -130.8 -130843 15.2 HDGF TBP PKNOX1 TBL1XR1 WRNIP1 SIN3A BMI1 FEZF1 EGR1 FOS ENSG00000198580 ENSG00000228010 ACTB FBXL18 MIR589 FSCN1 RNF216 WIPI2 USP42 CCZ1
GH07F005665 0.8 Ensembl ENCODE 13 -101.7 -101718 0.6 CTCF ESRRA SAP130 ARNT ARID4B BACH1 RAD21 ZKSCAN1 ZNF143 SMC3 ACTB FSCN1 FBXL18 MIR589 TNRC18 LOC100129484 RNF216-IT1
GH07F005661 1.1 Ensembl ENCODE 13 -98.5 -98485 1.8 PKNOX1 JUN MAX POLR2A EED ETV6 ZNF600 PRDM10 NFE2 FOS ACTB FSCN1 FBXL18 OCM RNF216-IT1
GH07F005666 0.8 Ensembl ENCODE 12.9 -103.7 -103707 1.4 IKZF1 CEBPB REST ZBTB20 ZNF18 NR2F2 ACTB FBXL18 MIR589 FSCN1 LOC100129484 TNRC18 RNF216-IT1
GH07F005667 0.2 ENCODE 12.9 -102.9 -102901 0.2 ACTB FBXL18 MIR589 FSCN1 LOC100129484 TNRC18 RNF216-IT1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ACTB on UCSC Golden Path with GeneCards custom track

Promoters for ACTB Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001888828 -16 401 ARID4B SIN3A ZNF48 ZNF2 ZNF121 GLIS2 ZNF207 ZNF143 KLF7 SP5
ENSR00000621431 1183 1600 ATF1 CREB3L1 MLX ARID4B SIN3A ETS1 ZNF121 ZNF143 KLF7 FOS

Genomic Location for ACTB Gene

Chromosome:
7
Start:
5,527,148 bp from pter
End:
5,563,784 bp from pter
Size:
36,637 bases
Orientation:
Minus strand

Genomic View for ACTB Gene

Genes around ACTB on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ACTB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ACTB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ACTB Gene

Proteins for ACTB Gene

  • Protein details for ACTB Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P60709-ACTB_HUMAN
    Recommended name:
    Actin, cytoplasmic 1
    Protein Accession:
    P60709
    Secondary Accessions:
    • P02570
    • P70514
    • P99021
    • Q11211
    • Q64316
    • Q75MN2
    • Q96B34
    • Q96HG5

    Protein attributes for ACTB Gene

    Size:
    375 amino acids
    Molecular mass:
    41737 Da
    Quaternary structure:
    • Interacts with CPNE1 (via VWFA domain) and CPNE4 (via VWFA domain) (By similarity). Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Component of the MLL5-L complex, at least composed of KMT2E/MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT. Interacts with XPO6 and EMD. Interacts with ERBB2. Interacts with GCSAM. Interacts with TBC1D21 (By similarity).
    Miscellaneous:
    • In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.

    Three dimensional structures from OCA and Proteopedia for ACTB Gene

neXtProt entry for ACTB Gene

Post-translational modifications for ACTB Gene

  • (Microbial infection) Monomeric actin is cross-linked by V.cholerae toxins RtxA and VgrG1 in case of infection: bacterial toxins mediate the cross-link between Lys-50 of one monomer and Glu-270 of another actin monomer, resulting in formation of highly toxic actin oligomers that cause cell rounding (PubMed:19015515). The toxin can be highly efficient at very low concentrations by acting on formin homology family proteins: toxic actin oligomers bind with high affinity to formins and adversely affect both nucleation and elongation abilities of formins, causing their potent inhibition in both profilin-dependent and independent manners (PubMed:26228148).
  • ISGylated.
  • Monomethylation at Lys-84 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.
  • Oxidation of Met-44 and Met-47 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promote actin repolymerization (By similarity).
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ACTB Gene

No data available for DME Specific Peptides for ACTB Gene

Domains & Families for ACTB Gene

Gene Families for ACTB Gene

HGNC:

Protein Domains for ACTB Gene

Graphical View of Domain Structure for InterPro Entry

P60709

UniProtKB/Swiss-Prot:

ACTB_HUMAN :
  • Belongs to the actin family.
Family:
  • Belongs to the actin family.
genes like me logo Genes that share domains with ACTB: view

Function for ACTB Gene

Molecular function for ACTB Gene

GENATLAS Biochemistry:
actin,beta,cytoplasmic,major constituent of microfilaments
UniProtKB/Swiss-Prot Function:
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Gene Ontology (GO) - Molecular Function for ACTB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding IDA 16217013
GO:0000980 contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding IDA 16217013
GO:0005200 structural constituent of cytoskeleton TAS 6202424
GO:0005515 protein binding IPI 14592989
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with ACTB: view
genes like me logo Genes that share phenotypes with ACTB: view

Human Phenotype Ontology for ACTB Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for ACTB Gene

MGI Knock Outs for ACTB:
  • Actb tm1Alj
  • Actb tm1.1(tetO-COP4*/EYFP)Kftnk
  • Actb tm2.1Npa

Animal Model Products

miRNA for ACTB Gene

miRTarBase miRNAs that target ACTB

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for ACTB

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for ACTB Gene

Localization for ACTB Gene

Subcellular locations from UniProtKB/Swiss-Prot for ACTB Gene

Cytoplasm, cytoskeleton. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ACTB Gene COMPARTMENTS Subcellular localization image for ACTB gene
Compartment Confidence
cytoskeleton 5
cytosol 5
extracellular 5
nucleus 5
plasma membrane 4
mitochondrion 2
endoplasmic reticulum 1
golgi apparatus 1
lysosome 1
peroxisome 1
vacuole 1

Gene Ontology (GO) - Cellular Components for ACTB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000790 nuclear chromatin IDA 16217013
GO:0005615 extracellular space IDA 16502470
GO:0005654 nucleoplasm TAS --
GO:0005737 cytoplasm TAS 16130169
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with ACTB: view

Pathways & Interactions for ACTB Gene

SuperPathways for ACTB Gene

genes like me logo Genes that share pathways with ACTB: view

Pathways by source for ACTB Gene

Gene Ontology (GO) - Biological Process for ACTB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001895 retina homeostasis IEP 23580065
GO:0006928 movement of cell or subcellular component TAS 6202424
GO:0007010 cytoskeleton organization IEA --
GO:0021762 substantia nigra development IEP 22926577
GO:0034329 cell junction assembly TAS --
genes like me logo Genes that share ontologies with ACTB: view

No data available for SIGNOR curated interactions for ACTB Gene

Drugs & Compounds for ACTB Gene

(8) Drugs for ACTB Gene - From: ApexBio and Tocris

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Latrunculin A Experimental Pharma Inhibitor of actin assembly and polymerization 0
Cytochalasin D Pharma inhibitor of actin polymerization, selective, Disrupts actin filament function 0
Jasplakinolide Pharma Stabilizes F-actin; promotes actin polymerization 0
CK 666 Pharma 0
CK 869 Pharma 0

(3) Additional Compounds for ACTB Gene - From: Tocris and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Cytochalasin B
14930-96-2
Thymosin beta4
77591-33-4

(5) Tocris Compounds for ACTB Gene

Compound Action Cas Number
Cytochalasin B Inhibitor of actin polymerization 14930-96-2
Cytochalasin D Disrupts actin filament function 22144-77-0
Jasplakinolide Stabilizes F-actin; promotes actin polymerization 102396-24-7
Latrunculin A Inhibitor of actin assembly and polymerization 76343-93-6
Thymosin beta4 Potent actin polymerization regulator 77591-33-4

(8) ApexBio Compounds for ACTB Gene

Compound Action Cas Number
CK 666 442633-00-3
CK 869 388592-44-7
Cytochalasin D inhibitor of actin polymerization, selective 22144-77-0
Jasplakinolide 102396-24-7
Latrunculin A 76343-93-6
Phalloidin 17466-45-4
SMIFH2 340316-62-3
Wiskostatin 253449-04-6
genes like me logo Genes that share compounds with ACTB: view

Transcripts for ACTB Gene

Unigene Clusters for ACTB Gene

Actin, beta:
Representative Sequences:

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for ACTB

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ACTB Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d · 5e · 5f ^ 6a · 6b · 6c ^ 7
SP1: - - - -
SP2: - - - - - -
SP3: - - - - - -
SP4: - - -
SP5: - - - - -
SP6: - - - - - - - - - -
SP7: - -
SP8: - - - -
SP9:
SP10: -

Relevant External Links for ACTB Gene

GeneLoc Exon Structure for
ACTB
ECgene alternative splicing isoforms for
ACTB

Expression for ACTB Gene

mRNA expression in normal human tissues for ACTB Gene

mRNA differential expression in normal tissues according to GTEx for ACTB Gene

This gene is overexpressed in Whole Blood (x4.5).

Protein differential expression in normal tissues from HIPED for ACTB Gene

This gene is overexpressed in Neutrophil (11.1), Tlymphocyte (8.7), and Lavage (7.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ACTB Gene



NURSA nuclear receptor signaling pathways regulating expression of ACTB Gene:

ACTB

SOURCE GeneReport for Unigene cluster for ACTB Gene:

Hs.520640
genes like me logo Genes that share expression patterns with ACTB: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ACTB Gene

Orthologs for ACTB Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ACTB Gene

Organism Taxonomy Gene Similarity Type Details
oppossum
(Monodelphis domestica)
Mammalia ACTB 35
  • 100 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ACTB 35
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ACTB 34 35
  • 99.47 (n)
-- 35
  • 46 (a)
OneToMany
cow
(Bos Taurus)
Mammalia ACTB 34 35
  • 93.78 (n)
dog
(Canis familiaris)
Mammalia ACTB 34 35
  • 93.78 (n)
rat
(Rattus norvegicus)
Mammalia Actb 34
  • 92.44 (n)
mouse
(Mus musculus)
Mammalia Actb 34 16 35
  • 91.91 (n)
chicken
(Gallus gallus)
Aves gga-mir-3533 35
  • 100 (a)
OneToOne
ACTB 34
  • 88.27 (n)
lizard
(Anolis carolinensis)
Reptilia ACTB 35
  • 95 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia actb 34
  • 81.6 (n)
zebrafish
(Danio rerio)
Actinopterygii actb1 35
  • 99 (a)
ManyToMany
bactin2 34
fruit fly
(Drosophila melanogaster)
Insecta Act5C 36
  • 98 (a)
Act42A 36
  • 97 (a)
Act57B 36 35
  • 95 (a)
Act88F 36
  • 95 (a)
Act79B 36
  • 94 (a)
Act87E 36 34
  • 85.12 (n)
Arp53D 36
  • 64 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005095 34
  • 84.49 (n)
worm
(Caenorhabditis elegans)
Secernentea act-2 36 35
  • 98 (a)
act-1 36
  • 97 (a)
act-3 36
  • 97 (a)
act-5 36
  • 93 (a)
F42C5.9 36
  • 28 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ACT1 35 37
  • 89 (a)
OneToMany
rice
(Oryza sativa)
Liliopsida Os05g0438800 34
  • 73.8 (n)
Os.3420 34
barley
(Hordeum vulgare)
Liliopsida Hv.8296 34
corn
(Zea mays)
Liliopsida Zm.6944 34
sea squirt
(Ciona savignyi)
Ascidiacea CSCA1 35
  • 97 (a)
ManyToMany
Species where no ortholog for ACTB was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ACTB Gene

ENSEMBL:
Gene Tree for ACTB (if available)
TreeFam:
Gene Tree for ACTB (if available)

Paralogs for ACTB Gene

genes like me logo Genes that share paralogs with ACTB: view

Variants for ACTB Gene

Sequence variations from dbSNP and Humsavar for ACTB Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs104894003 Dystonia, juvenile-onset (DJO) [MIM:607371], Pathogenic 5,528,536(-) CTGGC(C/T)GGGAC reference, missense
rs281875331 Baraitser-Winter syndrome 1 (BRWS1) [MIM:243310], Pathogenic 5,529,624(-) TCGAC(A/C/G)ACGGC reference, missense
rs281875332 Baraitser-Winter syndrome 1 (BRWS1) [MIM:243310], Pathogenic 5,529,331(-) GCATC(C/G/T)TCACC reference, missense
rs281875333 Baraitser-Winter syndrome 1 (BRWS1) [MIM:243310], Pathogenic 5,528,497(-) CCGAG(A/C/T)GCGGC reference, missense
rs281875334 Baraitser-Winter syndrome 1 (BRWS1) [MIM:243310], Pathogenic 5,528,496(-) CGAGC(A/G)CGGCT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ACTB Gene

Variant ID Type Subtype PubMed ID
dgv3482n106 OTHER inversion 24896259
esv25511 CNV loss 19812545
esv3571585 CNV loss 25503493
esv3611976 CNV loss 21293372
nsv436904 CNV insertion 17901297
nsv471304 CNV loss 18288195
nsv517558 CNV loss 19592680
nsv526194 CNV gain 19592680
nsv830890 CNV loss 17160897
nsv981426 CNV duplication 23825009

Variation tolerance for ACTB Gene

Residual Variation Intolerance Score: 11.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.06; 1.44% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ACTB Gene

Human Gene Mutation Database (HGMD)
ACTB
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ACTB

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACTB Gene

Disorders for ACTB Gene

MalaCards: The human disease database

(11) MalaCards diseases for ACTB Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
dystonia, juvenile-onset
  • juvenile-onset dystonia
baraitser-winter syndrome 1
  • iris coloboma with ptosis, hypertelorism, and mental retardation
baraitser-winter syndrome
  • brws
baraitser-winter cerebrofrontofacial syndrome
subacute glomerulonephritis
- elite association - COSMIC cancer census association via MalaCards
Search ACTB in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

ACTB_HUMAN
  • Baraitser-Winter syndrome 1 (BRWS1) [MIM:243310]: A rare developmental disorder characterized by the combination of congenital ptosis, high-arched eyebrows, hypertelorism, ocular colobomata, and a brain malformation consisting of anterior-predominant lissencephaly. Other typical features include postnatal short stature and microcephaly, intellectual disability, seizures, and hearing loss. {ECO:0000269 PubMed:22366783}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Dystonia, juvenile-onset (DJO) [MIM:607371]: A form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. Patients with juvenile-onset dystonia manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss. {ECO:0000269 PubMed:16685646}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Genatlas disease for ACTB Gene

recurrent infection,photosensitivity and mild mental retardation associated to abnormalities in neutrophil chemotaxis,superoxide production and membrane potential response

Relevant External Links for ACTB

Genetic Association Database (GAD)
ACTB
Human Genome Epidemiology (HuGE) Navigator
ACTB
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ACTB
genes like me logo Genes that share disorders with ACTB: view

Publications for ACTB Gene

  1. De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser- Winter syndrome. (PMID: 22366783) Riviere J.B. … Dobyns W.B. (Nat. Genet. 2012) 3 4 64
  2. Nuclear ErbB2 enhances translation and cell growth by activating transcription of ribosomal RNA genes. (PMID: 21555369) Li L.Y. … Hung M.C. (Cancer Res. 2011) 3 4 64
  3. [Establishment of a multiplex ligation-dependent SNP genotyping method and its application in the detection of genes related to chemotherapeutic drugs in breast cancer]. (PMID: 19538885) Tang J.H. … Xu Z.Y. (Zhonghua Zhong Liu Za Zhi 2009) 3 46 64
  4. Molecular composition of IMP1 ribonucleoprotein granules. (PMID: 17289661) Joeson L. … Nielsen F.C. (Mol. Cell. Proteomics 2007) 3 4 64
  5. HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration. (PMID: 17823310) Lu X. … Lossos I.S. (Blood 2007) 3 4 64

Products for ACTB Gene

Sources for ACTB Gene

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