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Aliases for ACT Gene

Aliases for ACT Gene

  • Actin-Like Protein (ACT) Gene 3

External Ids for ACT Gene

Previous GeneCards Identifiers for ACT Gene

  • GC06P096878
  • GC06P097027

Summaries for ACT Gene

GeneCards Summary for ACT Gene

ACT (Actin-Like Protein (ACT) Gene) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACT Gene

Genomics for ACT Gene

Genomic Location for ACT Gene

Unknown strand

Genomic View for ACT Gene

Cytogenetic band:
GeneLoc Logo Gene Density

No data available for Regulatory Elements and RefSeq DNA sequence for ACT Gene

Proteins for ACT Gene

  • Protein details for ACT Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Actin-like protein
    Protein Accession:

    Protein attributes for ACT Gene

    103 amino acids
    Molecular mass:
    11706 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ACT Gene

Post-translational modifications for ACT Gene

No Post-translational modifications

No data available for DME Specific Peptides for ACT Gene

Domains & Families for ACT Gene

Protein Domains for ACT Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ACT: view

No data available for Gene Families and UniProtKB/Swiss-Prot for ACT Gene

Function for ACT Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ACT Gene

Localization for ACT Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ACT Gene

Pathways & Interactions for ACT Gene

No Data Available

Interacting Proteins for ACT Gene

Gene Ontology (GO) - Biological Process for ACT Gene


No data available for Pathways by source and SIGNOR curated interactions for ACT Gene

Drugs & Compounds for ACT Gene

(107) Drugs for ACT Gene - From: ClinicalTrials

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Fludarabine Approved Pharma DNA synthsis inhibitor 1154,1154
Albendazole Approved, Vet_approved Pharma 85
Aldesleukin Approved Pharma 405
Amodiaquine Approved Pharma 99
Argatroban Approved, Investigational Pharma Thrombin mediated fibrinogen cleavage inhibitor 19
genes like me logo Genes that share compounds with ACT: view

Transcripts for ACT Gene

mRNA/cDNA for ACT Gene

(2) Selected AceView cDNA sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ACT Gene

No ASD Table

Expression for ACT Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from MaxQB and MOPED for ACT Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ACT Gene

Orthologs for ACT Gene

This gene was present in the common ancestor of animals.

Orthologs for ACT Gene

Organism Taxonomy Gene Similarity Type Details
fruit fly
(Drosophila melanogaster)
Insecta Lmpt 36
  • 48 (a)
(Caenorhabditis elegans)
Secernentea F25H5.1a 36
  • 48 (a)
F25H5.1b 36
  • 47 (a)
Species where no ortholog for ACT was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

No data available for Evolution for ACT Gene

Paralogs for ACT Gene

genes like me logo Genes that share paralogs with ACT: view

No data available for Paralogs for ACT Gene

Variants for ACT Gene

Relevant External Links for ACT Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for ACT Gene

Disorders for ACT Gene

Relevant External Links for ACT

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ACT Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ACT Gene

Publications for ACT Gene

  1. EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties. (PMID: 24488013) Miao H. … Wang B. (Oncogene 2015) 3 64
  2. Identification of a novel actin isoform in hepatocellular carcinoma. (PMID: 16824795) Chang K.-W. … Yeh C.-T. (Hepatol. Res. 2006) 3 64

Products for ACT Gene

Sources for ACT Gene

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