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ACSS3 Gene

protein-coding   GIFtS: 52
GCID: GC12P081331

Acyl-CoA Synthetase Short-Chain Family Member 3

  See ACSS3-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Acyl-CoA Synthetase Short-Chain Family Member 31 2 3
EC 6.2.1.13 8
Acyl-CoA Synthetase Short-Chain Family Member 3, Mitochondrial2
AMP-Binding Enzyme, 332172
EC 6.2.18

External Ids:    HGNC: 247231   Entrez Gene: 796112   Ensembl: ENSG000001110587   OMIM: 6143565   UniProtKB: Q9H6R33   

Export aliases for ACSS3 gene to outside databases

Previous GC identifers: GC12P079995 GC12P081471 GC12P078528


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ACSS3 Gene:
ACSS3 (acyl-CoA synthetase short-chain family member 3) is a protein-coding gene. Diseases associated with ACSS3 include fetal alcohol syndrome. GO annotations related to this gene include acetate-CoA ligase activity. An important paralog of this gene is AACS.

UniProtKB/Swiss-Prot: ACSS3_HUMAN, Q9H6R3
Function: Activates acetate so that it can be used for lipid synthesis or for energy generation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ACSS3 gene promoter:
         TBP   HFH-3   Pbx1a   FOXD3   CUTL1   GATA-1   Evi-1   FOXI1   TFIID   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidACSS3 promoter sequence
   Search Chromatin IP Primers for ACSS3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ACSS3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q21.31   Ensembl cytogenetic band:  12q21.31   HGNC cytogenetic band: 12q21.31

ACSS3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACSS3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P081331:  view genomic region     (about GC identifiers)

Start:
81,331,594 bp from pter      End:
81,650,533 bp from pter
Size:
318,940 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ACSS3_HUMAN, Q9H6R3 (See protein sequence)
Recommended Name: Acyl-CoA synthetase short-chain family member 3, mitochondrial precursor  
Size: 686 amino acids; 74778 Da
Secondary accessions: Q8NC66
Alternative splicing: 2 isoforms:  Q9H6R3-1   Q9H6R3-2   

Explore the universe of human proteins at neXtProt for ACSS3: NX_Q9H6R3

Explore proteomics data for ACSS3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ACSS3 (Q9H6R3) (see all 12)
     VVIYMPM  RIGAIHS  RVDDVINV  MLACARIGA 


    See ACSS3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_078836.1  
    ENSEMBL proteins: 
     ENSP00000447748   ENSP00000449535   ENSP00000261206   ENSP00000448965   ENSP00000449507  

    ACSS3 Human Recombinant Protein Products:

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    OriGene Purified Protein for ACSS3
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    Novus Biologicals ACSS3 Protein
    Novus Biologicals ACSS3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ACSS3

     
    Search eBioscience for Proteins for ACSS3 

    ACSS3 Antibody Products:

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    LSBio Antibodies in human, mouse, rat for ACSS3

    ACSS3 Assay Products:

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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ACSS3
    Cloud-Clone Corp. CLIAs for ACSS3
    Search eBioscience for ELISAs for ACSS3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ACS: Acyl-CoA synthetase family

    3 InterPro protein domains:
     IPR025110 AMP-bd_C
     IPR020845 AMP-binding_CS
     IPR000873 AMP-dep_Synth/Lig

    Graphical View of Domain Structure for InterPro Entry Q9H6R3

    ProtoNet protein and cluster: Q9H6R3

    1 Blocks protein domain: IPB000873 AMP-binding signature

    UniProtKB/Swiss-Prot: ACSS3_HUMAN, Q9H6R3
    Similarity: Belongs to the ATP-dependent AMP-binding enzyme family


    Find genes that share domains with ACSS3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ACSS3_HUMAN, Q9H6R3
    Function: Activates acetate so that it can be used for lipid synthesis or for energy generation (By similarity)
    Catalytic activity: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA

         Enzyme Numbers (IUBMB): EC 6.2.1.11 2 EC 6.2.12

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0003987acetate-CoA ligase activity IEA--
    GO:0005524ATP binding IEA--
         
    Find genes that share ontologies with ACSS3           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Acss3 (no phenotypes)

    Find genes that share phenotypes with ACSS3           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ACSS3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ACSS3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ACSS3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ACSS3

    miRNA
    Products:
        
    miRTarBase miRNAs that target ACSS3:
    hsa-mir-335-5p (MIRT017832)

    Block miRNA regulation of human, mouse, rat ACSS3 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate ACSS3:
    hsa-miR-23b hsa-miR-7-1* hsa-miR-7-2* hsa-miR-130a* hsa-miR-23a hsa-miR-23c
    SwitchGear 3'UTR luciferase reporter plasmidACSS3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ACSS3
    Predesigned siRNA for gene silencing in human, mouse, rat ACSS3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ACSS3

    Clone
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    OriGene ORF clones in mouse, rat for ACSS3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ACSS3 (NM_024560)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACSS3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACSS3

    Cell Line
    Products:
         
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    Browse ESI BIO Cell Lines and PureStem Progenitors for ACSS3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACSS3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ACSS3_HUMAN, Q9H6R3: Mitochondrion (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion3
    cytosol2
    extracellular1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--

    Find genes that share ontologies with ACSS3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ACSS3 About    
    See pathways by source

    SuperPathContained pathways About
    1ethanol degradation II
    ethanol degradation II0.57
    oxidative ethanol degradation III0.57
    ethanol degradation IV0.57
    acetate conversion to acetyl-CoA0.00
    2Metabolism
    Metabolic pathways0.38
    3Valine, leucine and isoleucine degradation
    Propanoate metabolism0.31


    Find genes that share SuperPaths with ACSS3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4 BioSystems Pathways for ACSS3
        oxidative ethanol degradation III
    ethanol degradation IV
    ethanol degradation II
    acetate conversion to acetyl-CoA


    2 Kegg Pathways  (Kegg details for ACSS3):
        Propanoate metabolism
    Metabolic pathways

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ACSS3
    Interactions:

        Search GeneGlobe Interaction Network for ACSS3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ACSS3 (ENSP000002612064) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACADMENSP000004096124STRING: ENSP00000409612
    ACSS1ENSP000003169244STRING: ENSP00000316924
    ACSS2ENSP000003538044STRING: ENSP00000353804
    ALDH3A2ENSP000003457744STRING: ENSP00000345774
    ALDH6A1ENSP000003425644STRING: ENSP00000342564
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152metabolic process ----

    Find genes that share ontologies with ACSS3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ACSS3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ACSS3 gene: 
    NM_024560.2  

    Unigene Cluster for ACSS3:

    Acyl-CoA synthetase short-chain family member 3
    Hs.259559  [show with all ESTs]
    Unigene Representative Sequence: CR627432
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000549175 ENST00000548058(uc001szl.1 uc001szm.1) ENST00000261206
    ENST00000548387 ENST00000548324(uc001szn.1) ENST00000551745 ENST00000546664

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ACSS3 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate ACSS3:
    hsa-miR-23b hsa-miR-7-1* hsa-miR-7-2* hsa-miR-130a* hsa-miR-23a hsa-miR-23c
    SwitchGear 3'UTR luciferase reporter plasmidACSS3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ACSS3
    Predesigned siRNA for gene silencing in human, mouse, rat ACSS3
    Clone
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    OriGene clones in human, mouse for ACSS3 (see all 7)
    OriGene ORF clones in mouse, rat for ACSS3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ACSS3 (NM_024560)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACSS3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACSS3
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ACSS3
    OriGene qSTAR qPCR primer pairs in human, mouse for ACSS3
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ACSS3
      QuantiTect SYBR Green Assays in human, mouse, rat ACSS3
      QuantiFast Probe-based Assays in human, mouse, rat ACSS3

    Additional mRNA sequence: 

    AK025616.1 AK074267.1 BC009317.2 BC015769.1 CR627432.1 

    5 DOTS entries:

    DT.109880  DT.86844808  DT.91859695  DT.453476  DT.97825294 

    Selected AceView cDNA sequences (see all 76):

    AI022900 AK025616 BM014516 F10065 BP374049 AA864587 AX764482 CB270660 
    BC009317 BI093568 BQ436493 NM_024560 BC015769 CD675076 AA436548 BU155744 
    AI540216 BX283996 BG617645 AA436575 BF343757 BF111259 BF475474 AI123815 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ACSS3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAATGTATGT
    ACSS3 Expression
    About this image


    ACSS3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Ovary (Reproductive System)
             Mature Granulosa Cells Antral Follicle
     
     NULL (Uncategorized)
             Vascular endothelial growth factor-induced cells
     
     Lung (Respiratory System)
    ACSS3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ACSS3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.259559
        Custom PCR Arrays for ACSS3
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ACSS3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACSS3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ACSS3 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Acss31 , 5 acyl-CoA synthetase short-chain family member 31, 5 85.95(n)1
    90.31(a)1
      10 (55.66 cM)5
    3806601  NM_001142804.11  NP_001136276.11 
     1069650825 
    chicken
    (Gallus gallus)
    Aves ACSS31 acyl-CoA synthetase short-chain family member 3 75.99(n)
    76.62(a)
      417875  XM_416118.4  XP_416118.2 
    lizard
    (Anolis carolinensis)
    Reptilia ACSS36
    acyl-CoA synthetase short-chain family member 3
    67(a)
    1 ↔ 1
    5(36833397-36902800)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BX755211.12   -- 75.47(n)    BX755211.1 
    zebrafish
    (Danio rerio)
    Actinopterygii acss31 acyl-CoA synthetase short-chain family member 3 66.03(n)
    70.27(a)
      566019  XM_689284.6  XP_694376.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG64321 CG6432 51.55(n)
    47.44(a)
      42901  NM_142990.2  NP_651247.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ACS26
    Acetyl-coA synthetase isoform which, along with Ac...
    32(a)
    1 → many
    XII(445524-447575) YLR153C


    ENSEMBL Gene Tree for ACSS3 (if available)
    TreeFam Gene Tree for ACSS3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ACSS3 gene
    AACS2  
    5 SIMAP similar genes for ACSS3 using alignment to 3 protein entries:     ACSS3_HUMAN (see all proteins):
    DKFZp666G0810    ACSS2    DKFZp762G026    ACSS1    AACS

    Find genes that share paralogs with ACSS3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ACSS3 (see all 3439)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs597654391,2
    C--78608696(+) ACACA-/CAAATCC 1 -- int11Minor allele frequency- CA:0.00NA 2
    rs114486641,2
    C--81469849(+) CCTCC-/C/TC  
            
    CCACT
    1 -- us2k12NA CSA 4
    rs71330941,2
    C,F,A,H--81469861(+) TTTAAG/ATCATA 1 -- us2k123Minor allele frequency- A:0.34NS EA NA WA CSA 2354
    rs1413596841,2
    --81469972(+) GATTCC/TCTTTC 1 -- us2k10--------
    rs1450957261,2
    C--81469984(+) GTGGAC/GTTTCT 1 -- us2k10--------
    rs113516571,2
    C--81470048(+) TAAGA-/TTTTTT 1 -- us2k1 trp31Minor allele frequency- T:0.00CSA 2
    rs605707111,2
    C--81470063(+) TTTTT-/T/TT  
            
    AAAGT
    1 -- us2k11NA 2
    rs1389001501,2
    --81470074(+) AGAAGA/GTACTC 1 -- us2k10--------
    rs65395521,2
    C,F,A,H--81470096(+) AAAATC/GGTGGA 1 -- us2k124Minor allele frequency- G:0.30NS EA NA WA CSA 1360
    rs1881619381,2
    --81470219(+) CTCCAC/TCTTGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ACSS3 (81331594 - 81581594 bp, first 250kb of ACSS3)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ACSS3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2746118CNV Deletion23290073

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ACSS3
    DNA2.0 Custom Variant and Variant Library Synthesis for ACSS3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614356    OMIM disorders: --

    1 disease for ACSS3:    
    About MalaCards
    fetal alcohol syndrome

    1 disease from the University of Copenhagen DISEASES database for ACSS3:
    Fetal alcohol syndrome

    Find genes that share disorders with ACSS3           About GenesLikeMe

    Genetic Association Database (GAD): ACSS3
    Human Genome Epidemiology (HuGE) Navigator: ACSS3 (1 document)

    Export disorders for ACSS3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ACSS3 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with ACSS3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome. (PubMed id 17762044)1, 2, 3 Watkins P.A.... Pevsner J. (J. Lipid Res. 2007)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. A genome-wide association study of a sustained pattern of antidepressant response. (PubMed id 23726668)1 Hunter A.M....Hamilton S.P. (J Psychiatr Res 2013)
    4. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (BMC Med. Genet. 2007)
    7. Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. (PubMed id 17903295)4 Lunetta K.L....Murabito J.M. (BMC Med. Genet. 2007)
    8. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PubMed id 17903292)4 Hwang S.J....Fox C.S. (BMC Med. Genet. 2007)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79611 HGNC: 24723 AceView: FLJ21963 Ensembl:ENSG00000111058 euGenes: HUgn79611
    ECgene: ACSS3 Kegg: 79611 H-InvDB: ACSS3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ACSS3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ACSS3 gene:
    Search GeneIP for patents involving ACSS3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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