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ACSM2A Gene

protein-coding   GIFtS: 52
GCID: GC16P020463

Acyl-CoA Synthetase Medium-Chain Family Member 2A

(Previous name: acyl-CoA synthetase medium-chain family member 2)
(Previous symbol: ACSM2)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Acyl-CoA Synthetase Medium-Chain Family Member 2A1 2 3     Acyl-CoA Synthetase Medium-Chain Family Member 21
ACSM21 2 3     A-923A4.12
Butyrate--CoA Ligase 2A2 3     Acyl-Coenzyme A Synthetase ACSM2A, Mitochondrial2
Butyryl-Coenzyme A Synthetase 2A2 3     Homolog Of Rat Kidney-Specific (KS)2
Middle-Chain Acyl-CoA Synthetase 2A2 3     MACS23
EC 6.2.1.23 8     EC 6.2.18

External Ids:    HGNC: 320171   Entrez Gene: 1238762   Ensembl: ENSG000001837477   OMIM: 6143585   UniProtKB: Q08AH33   

Export aliases for ACSM2A gene to outside databases

Previous GC identifers: GC16P020372 GC16P018999


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ACSM2A Gene:
ACSM2A (acyl-CoA synthetase medium-chain family member 2A) is a protein-coding gene. GO annotations related to this gene include butyrate-CoA ligase activity. An important paralog of this gene is C10orf129.

UniProtKB/Swiss-Prot: ACS2A_HUMAN, Q08AH3
Function: Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on
acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro) (By
similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NT_187260.1  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ACSM2A gene promoter:
         STAT5B   STAT1   AML1a   STAT4   ATF-2   STAT1beta   STAT5A   STAT1alpha   STAT2   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidACSM2A promoter sequence
   Search Chromatin IP Primers for ACSM2A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ACSM2A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.3   Ensembl cytogenetic band:  16p12.3   HGNC cytogenetic band: 16p12.3

ACSM2A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACSM2A gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P020463:  view genomic region     (about GC identifiers)

Start:
20,462,783 bp from pter      End:
20,498,991 bp from pter
Size:
36,209 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ACS2A_HUMAN, Q08AH3 (See protein sequence)
Recommended Name: Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor  
Size: 577 amino acids; 64223 Da
Cofactor: Magnesium or manganese
Subunit: Monomer (By similarity)
Sequence caution: Sequence=AAC23497.1; Type=Erroneous gene model prediction;
Selected PDB 3D structures from and Proteopedia for ACSM2A (see all 7):
2VZE (3D)        2WD9 (3D)        3B7W (3D)        3C5E (3D)        3DAY (3D)        3EQ6 (3D)    
Secondary accessions: B3KTT9 O75202

Explore the universe of human proteins at neXtProt for ACSM2A: NX_Q08AH3

Explore proteomics data for ACSM2A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for ACSM2A (Q08AH3) (see all 7)
     APYKYPR  SGYRIGP  GNVLPPG  DILYRLQ 


    See ACSM2A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001010845.1  
    ENSEMBL proteins: 
     ENSP00000460153   ENSP00000460948   ENSP00000392169   ENSP00000459451   ENSP00000219054  
     ENSP00000460349   ENSP00000460884   ENSP00000460031   ENSP00000379411   ENSP00000394904  
     ENSP00000445082  
    Reactome Protein details: Q08AH3

    ACSM2A Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ACS: Acyl-CoA synthetase family

    3 InterPro protein domains:
     IPR025110 AMP-bd_C
     IPR020845 AMP-binding_CS
     IPR000873 AMP-dep_Synth/Lig

    Graphical View of Domain Structure for InterPro Entry Q08AH3

    ProtoNet protein and cluster: Q08AH3

    1 Blocks protein domain: IPB000873 AMP-binding signature

    UniProtKB/Swiss-Prot: ACS2A_HUMAN, Q08AH3
    Similarity: Belongs to the ATP-dependent AMP-binding enzyme family


    Find genes that share domains with ACSM2A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ACS2A_HUMAN, Q08AH3
    Function: Has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on
    acids from C(4) to C(11) and on the corresponding 3-hydroxy- and 2,3- or 3,4-unsaturated acids (in vitro) (By
    similarity)
    Catalytic activity: ATP + a carboxylate + CoA = AMP + diphosphate + an acyl-CoA

         Enzyme Numbers (IUBMB): EC 6.2.1.21 2 EC 6.2.12

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0005524ATP binding IEA--
    GO:0046872metal ion binding IEA--
    GO:0047760butyrate-CoA ligase activity IDA19345228
         
    Find genes that share ontologies with ACSM2A           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Acsm2 (no phenotypes)

    Find genes that share phenotypes with ACSM2A           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Acsm2tm1.1(KOMP)Vlcg for ACSM2A

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ACSM2A
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ACSM2A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ACSM2A

    miRNA
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    miRTarBase miRNAs that target ACSM2A:
    hsa-mir-18a-3p (MIRT040745)

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    3 qRT-PCR Assays for microRNAs that regulate ACSM2A:
    hsa-miR-623 hsa-miR-186 hsa-miR-2113
    SwitchGear 3'UTR luciferase reporter plasmidACSM2A 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat ACSM2A

    Gene Editing
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACSM2A

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACSM2A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ACS2A_HUMAN, Q08AH3: Mitochondrion matrix (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion4
    nucleus2
    cytosol1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion NAS19634011
    GO:0005759mitochondrial matrix IEA--

    Find genes that share ontologies with ACSM2A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ACSM2A About    
    See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolism0.38
    Metabolic pathways0.38
    2Conjugation of carboxylic acids
    Conjugation of carboxylic acids0.30
    Amino Acid conjugation0.00
    Conjugation of salicylate with glycine0.00
    3Biological oxidations
    Biological oxidations0.56
    Phase II conjugation0.56
    4Valproic Acid Pathway, Pharmacokinetics
    Valproic Acid Pathway, Pharmacokinetics
    5Butanoate metabolism
    Butanoate metabolism


    Find genes that share SuperPaths with ACSM2A           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for ACSM2A
        Conjugation of salicylate with glycine

    1 PharmGKB Pathway for ACSM2A
        Valproic Acid Pathway, Pharmacokinetics

    2 Kegg Pathways  (Kegg details for ACSM2A):
        Butanoate metabolism
    Metabolic pathways

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ACSM2A
    Interactions:

        Search GeneGlobe Interaction Network for ACSM2A

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for ACSM2A (ENSP000002190544) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACADSENSP000002425924STRING: ENSP00000242592
    CCSENSP000003078704STRING: ENSP00000307870
    MON2ENSP000003772524STRING: ENSP00000377252
    ALG6ENSP000003601494STRING: ENSP00000360149
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006631fatty acid metabolic process IEA--
    GO:0008152metabolic process ----
    GO:0036112medium-chain fatty-acyl-CoA metabolic process IDA19345228
    GO:0042593glucose homeostasis NAS16521160
    GO:0070328triglyceride homeostasis NAS16521160

    Find genes that share ontologies with ACSM2A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
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    Browse Tocris compounds for ACSM2A (ACS2A)

    Selected HMDB Compounds for ACSM2A (see all 40)    About this table
    CompoundSynonyms CAS #PubMed Ids
    (2E)-Decenoyl-CoA(E)-S-2-decenoate Coenzyme A (see all 15)10018-95-8--
    (2E)-Dodecenoyl-CoA2-trans-Dodecenoyl-Coenzyme A (see all 4)1066-12-2--
    (2E)-Hexadecenoyl-CoAtrans-2-Hexadecenoyl-CoA (see all 4)4460-95-1--
    (2E)-Octenoyl-CoA(E)-S-2-octenoate Coenzyme A (see all 16)10018-94-7--
    (2E)-Tetradecenoyl-CoA(2E)-Tetradecenoyl-Coenzyme A (see all 8)38795-33-4--
    2-Methylbutyryl-CoA2-methylbutanoyl-CoA (see all 11)6712-02-3--
    2-Methylhexanoyl-CoA2-Methylhexanoyl-CoEnzyme A (see all 5)----
    3Z-dodecenoyl-CoAS-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-dodec-3-enethioate (see all 4)2152-91-2--
    Acetyl-CoAS-Acetyl coenzyme A (see all 13)72-89-9--
    Acrylyl-CoAAcryloyl coenzyme A (see all 14)5776-58-9--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ACSM2A gene: 
    NM_001010845.2  

    Unigene Cluster for ACSM2A:

    Acyl-CoA synthetase medium-chain family member 2A
    Hs.656497  [show with all ESTs]
    Unigene Representative Sequence: AK091978
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000574251 ENST00000570698(uc010bwd.1 uc010vax.1) ENST00000576361
    ENST00000417235 ENST00000575558 ENST00000573854(uc010bwe.3 uc002dhf.4 uc002dhg.4 uc010vay.2 uc002dhh.4)
    ENST00000219054 ENST00000575690 ENST00000571204 ENST00000574692 ENST00000571894
    ENST00000572921 ENST00000572843 ENST00000576101 ENST00000576119 ENST00000396104
    ENST00000424070 ENST00000536134
    miRNA
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    hsa-miR-623 hsa-miR-186 hsa-miR-2113
    SwitchGear 3'UTR luciferase reporter plasmidACSM2A 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat ACSM2A

    Additional mRNA sequence: AK091978.1 

    1 DOTS entry:

    DT.40109306 

    Selected AceView cDNA sequences (see all 132):

    BX099043 AI340924 AV658242 AI768627 AI311802 N59778 BX496501 BF593572 
    AI624610 T61189 AV656515 AA873319 AI075158 AV718390 CB156950 AA938341 
    AW204090 BI760584 BV205430 AI733129 BV205444 BV205432 AV647248 AI493860 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ACSM2A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGTGACTTC
    ACSM2A Expression
    About this image

    ACSM2A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ACSM2A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.656497
        Custom PCR Arrays for ACSM2A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACSM2A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ACSM2A gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Acsm21 , 5 acyl-CoA synthetase medium-chain family member 21, 5 81.01(n)1
    76.31(a)1
      7 (63.97 cM)5
    2337991  NM_001177977.11  NP_001171448.11 
     1195614935 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG114536
    --
    19(a)
    many ↔ many
    3R(15609245-15611252)
    worm
    (Caenorhabditis elegans)
    Secernentea acs-166
    Protein ACS-16 (acs-16) mRNA, complete cds
    17(a)
    1 → many
    I(1471297-1479924) WBGene00018579


    ENSEMBL Gene Tree for ACSM2A (if available)
    TreeFam Gene Tree for ACSM2A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ACSM2A gene
    C10orf1292  ACSM52  ACSM32  ACSS22  ACSM12  ACSM42  ACSM2B2  ACSS12  
    ACSF22  
    9 SIMAP similar genes for ACSM2A using alignment to 7 protein entries:     ACS2A_HUMAN (see all proteins):
    ACSM2B    A-923A4.2    C10orf129    ACSM4    ACSM5    ACSM3
    NPIPB5    ACSM1    ACSM6

    Find genes that share paralogs with ACSM2A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ACSM2A (see all 1085)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1481420471,2
    Cuntested120501147(+) TCAACG/AAGCCA 2 /Q /R mis11Minor allele frequency- A:0.00NA 4552
    rs2017403971,2
    --20461055(+) TTAAA-/TTTTTT 1 -- us2k10--------
    rs2015671851,2
    C--20465268(+) GAGACA/GCTATT 1 -- us2k10--------
    rs798656221,2
    C,F--20466126(+) AGGCTG/ATAGGA 1 -- ut512Minor allele frequency- A:0.50NA 6
    rs1505833501,2
    C--20466165(+) GTGGAC/TGAAGC 1 -- ut510--------
    rs2020168501,2
    C--20466388(+) GGCACC/GTTTAT 1 -- int10--------
    rs1925524941,2
    --20466412(+) AGAGAC/TGAGGG 1 -- int10--------
    rs752058341,2
    C,F--20466443(+) CAGGGG/TGCTGG 1 -- int12Minor allele frequency- T:0.38NA 8
    rs1395652661,2
    C--20466498(+) GACCAA/GAAGAA 1 -- int10--------
    rs1478295781,2
    --20466605(+) ATTCCA/GTAGAA 1 -- int10--------

    HapMap Linkage Disequilibrium report for ACSM2A (20462783 - 20498991 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ACSM2A (see all 18):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2675909CNV Deletion23128226
    nsv436835CNV Insertion17901297
    nsv516604CNV Loss19592680
    nsv1760CNV Loss18451855
    dgv346n27CNV Loss19166990
    nsv525413CNV Loss19592680
    dgv48n17CNV Loss16327808
    esv26098CNV Loss19812545
    nsv9389CNV Loss18304495
    nsv437805CNV Loss16327808

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614358    OMIM disorders: --


    Find genes that share disorders with ACSM2A           About GenesLikeMe

    Genetic Association Database (GAD): ACSM2A
    Human Genome Epidemiology (HuGE) Navigator: ACSM2A (1 document)

    Export disorders for ACSM2A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ACSM2A gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with ACSM2A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A. (PubMed id 19345228)1, 2 Kochan G.... Yue W.W. (J. Mol. Biol. 2009)
    3. The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population. (PubMed id 16521160)1, 2 Lindner I.... Doering F. (Mol. Nutr. Food Res. 2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PubMed id 10493829)1, 2 Loftus B.J.... Adams M.D. (Genomics 1999)
    6. Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines. (PubMed id 19634011)1 Boomgaarden I.... Doering F. (Biochem. Genet. 2009)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (Nature 2004)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. An acyl-CoA synthetase gene family in chromosome 16p12 may contribute to multiple risk factors. (PubMed id 12654705)2 Iwai N.... Iwanaga Y. (Hypertension 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 123876 HGNC: 32017 AceView: LOC123876 Ensembl:ENSG00000183747 euGenes: HUgn123876
    ECgene: ACSM2A Kegg: 123876 H-InvDB: ACSM2A

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ACSM2A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ACSM2A gene:
    Search GeneIP for patents involving ACSM2A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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