Aliases for ACSL6 Gene
Aliases for ACSL6 Gene
External Ids for ACSL6 Gene
- HGNC: 16496
- Entrez Gene: 23305
- Ensembl: ENSG00000164398
- OMIM: 604443
- UniProtKB: Q9UKU0
Previous HGNC Symbols for ACSL6 Gene
- FACL6
Previous GeneCards Identifiers for ACSL6 Gene
- GC05M131366
- GC05M131170
- GC05M126481
- GC05M131144
- GC05M131145
- GC05M131146
- GC05M131147
- GC05M131808
Summaries for ACSL6 Gene
-
The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011]
GeneCards Summary for ACSL6 Gene
ACSL6 (Acyl-CoA Synthetase Long-Chain Family Member 6) is a Protein Coding gene. Diseases associated with ACSL6 include Myelodysplastic Syndrome and Chronic Intestinal Vascular Insufficiency. Among its related pathways are Fatty Acyl-CoA Biosynthesis and Peroxisome. GO annotations related to this gene include protein homodimerization activity and long-chain fatty acid-CoA ligase activity. An important paralog of this gene is ENSG00000281938.
UniProtKB/Swiss-Prot for ACSL6 Gene
-
Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACSL6 Gene
Genomics for ACSL6 Gene
Regulatory Elements for ACSL6 Gene
Enhancers for ACSL6 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ACSL6 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ACSL6 gene promoter:
Regulatory Element Products
Genomic Location for ACSL6 Gene
- Chromosome:
- 5
- Start:
- 131,949,973 bp from pter
- End:
- 132,012,243 bp from pter
- Size:
- 62,271 bases
- Orientation:
- Minus strand
Genomic View for ACSL6 Gene
Genes around ACSL6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q31.1 by Ensembl
- 5q31.1 by Entrez Gene
- 5q31.1 by HGNC
ACSL6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ACSL6 Gene
Proteins for ACSL6 Gene
-
Protein details for ACSL6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UKU0-ACSL6_HUMAN
- Recommended name:
- Long-chain-fatty-acid--CoA ligase 6
- Protein Accession:
- Q9UKU0
- J3KPG3
- O94924
- O95829
- Q108M9
- Q108N0
- Q4G191
- Q86TN7
Protein attributes for ACSL6 Gene
- Size:
- 697 amino acids
- Molecular mass:
- 77752 Da
- Cofactor:
- Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH26161.1; Type=Erroneous termination; Positions=72; Note=Translated as Arg.; Evidence={ECO:0000305}; Sequence=BAA74860.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for ACSL6 Gene
Selected DME Specific Peptides for ACSL6 Gene
- Q9UKU0:
-
- VPLYDTLG
- GFFQGDIRLL
- FAQNRPEW
- KGAMLTH
- PGDWTSGHVG
- NVFKGYLKD
- CFTSGTTGNPKGAM
- DGWLHTGD
- NGLLTPTLKAKR
- LKIIDRKK
- LPLAHMFE
- YGQTECT
- DGWLHTGDIGKWLP
Post-translational modifications for ACSL6 Gene
Other Protein References for ACSL6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ACSL6
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- Invitrogen Antibodies for ACSL6
- antibodies-online Antibodies for ACSL6: See all 41
- GeneTex ACSL6 antibody for ACSL6
Protein Products
-
OriGene Purified Proteins for ACSL6
- Search Origene for MassSpec and Protein Over-expression Lysates for ACSL6
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- Novus Biologicals proteins for ACSL6
- antibodies-online Proteins for ACSL6: See all 7
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ACSL6
Assay Products
Domains & Families for ACSL6 Gene
Gene Families for ACSL6 Gene
Protein Domains for ACSL6 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ACSL6 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9UKU0- Family:
-
- Belongs to the ATP-dependent AMP-binding enzyme family.
Function for ACSL6 Gene
Molecular function for ACSL6 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA.
- UniProtKB/Swiss-Prot Function:
- Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
Enzyme Numbers (IUBMB) for ACSL6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003824 | catalytic activity | IEA | -- |
| GO:0004467 | long-chain fatty acid-CoA ligase activity | TAS | -- |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0016874 | ligase activity | IEA | -- |
| GO:0042803 | protein homodimerization activity | IDA | 20429931 |
Phenotypes for ACSL6 Gene
- GenomeRNAi human phenotypes for ACSL6:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ACSL6
-
- Search ViGene Biosciences for ACSL6
CRISPR Products
-
OriGene CRISPR knockouts for ACSL6
-
Santa Cruz Biotechnology (SCBT) CRISPR for ACSL6
- GenScript: Design CRISPR guide RNA sequences for ACSL6
miRNA for ACSL6 Gene
- miRTarBase miRNAs that target ACSL6
-
- hsa-mir-34a-5p (MIRT025504)
- hsa-mir-580-3p (MIRT445412)
- hsa-mir-526b-5p (MIRT445413)
- hsa-mir-431-5p (MIRT445414)
- hsa-mir-539-5p (MIRT445415)
- hsa-mir-4277 (MIRT445416)
- hsa-mir-5584-3p (MIRT445417)
- hsa-mir-4659b-3p (MIRT504007)
- hsa-mir-4659a-3p (MIRT504008)
- hsa-mir-6875-3p (MIRT504009)
- hsa-mir-629-3p (MIRT504010)
- hsa-mir-670-3p (MIRT504011)
- hsa-mir-6867-3p (MIRT504012)
- hsa-mir-4713-5p (MIRT504013)
- hsa-mir-942-5p (MIRT504014)
- hsa-mir-4682 (MIRT504015)
- hsa-mir-4653-5p (MIRT504016)
- hsa-mir-2116-3p (MIRT504017)
- hsa-mir-3921 (MIRT504018)
- hsa-mir-532-3p (MIRT504019)
- hsa-mir-150-5p (MIRT504020)
- hsa-mir-6814-5p (MIRT504021)
- hsa-mir-4714-5p (MIRT504022)
- hsa-mir-618 (MIRT504023)
- hsa-mir-4524b-3p (MIRT669621)
- hsa-mir-1206 (MIRT669622)
- hsa-mir-4284 (MIRT669623)
- hsa-mir-6778-3p (MIRT669624)
- hsa-mir-2276-3p (MIRT669625)
- hsa-mir-4638-5p (MIRT669626)
- hsa-mir-1307-3p (MIRT669627)
- hsa-mir-1304-3p (MIRT669628)
- hsa-mir-6741-3p (MIRT669629)
- hsa-mir-1281 (MIRT669630)
- hsa-mir-4485-5p (MIRT669631)
- hsa-mir-4726-3p (MIRT669632)
- hsa-mir-6764-5p (MIRT669633)
- hsa-mir-1915-3p (MIRT669634)
- hsa-mir-6840-3p (MIRT669635)
- hsa-mir-6890-3p (MIRT669636)
miRNA Products
- Search ViGene Biosciences for ACSL6
Inhibitory RNA Products
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Clone Products
- Sino Biological Human cDNA Clone for ACSL6
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- VectorBuilder custom plasmid, inducible vectors for ACSL6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACSL6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ACSL6
Flow Cytometry Products
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ACSL6 Gene
Localization for ACSL6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ACSL6 Gene
- Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| endoplasmic reticulum | 5 |
| mitochondrion | 4 |
| peroxisome | 4 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA | -- |
| GO:0005741 | mitochondrial outer membrane | IEA | -- |
| GO:0005777 | peroxisome | IEA | -- |
| GO:0005778 | peroxisomal membrane | IEA | -- |
| GO:0005783 | endoplasmic reticulum | IEA | -- |
Pathways & Interactions for ACSL6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism |
.37
|
|
| 2 | Fatty Acyl-CoA Biosynthesis | ||
| 3 | Fatty acid metabolism | ||
| 4 | Adipocytokine signaling pathway | ||
| 5 | Fatty acid biosynthesis (KEGG) | ||
Pathways by source for ACSL6 Gene
2 BioSystems pathways for ACSL6 Gene
8 KEGG pathways for ACSL6 Gene
Interacting Proteins for ACSL6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001676 | long-chain fatty acid metabolic process | IEA | -- |
| GO:0006629 | lipid metabolic process | IEA | -- |
| GO:0006631 | fatty acid metabolic process | IEA | -- |
| GO:0006637 | acyl-CoA metabolic process | NAS | 10548543 |
| GO:0008152 | metabolic process | IEA | -- |
No data available for SIGNOR curated interactions for ACSL6 Gene
Drugs & Compounds for ACSL6 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| (2E)-Decenoyl-CoA |
|
10018-95-8 |
|
|||
| (2E)-Dodecenoyl-CoA |
|
1066-12-2 |
|
|||
| (2E)-Hexadecenoyl-CoA |
|
4460-95-1 |
|
|||
| (2E)-Octenoyl-CoA |
|
10018-94-7 |
|
|||
| (2E)-Tetradecenoyl-CoA |
|
38795-33-4 |
|
Transcripts for ACSL6 Gene
mRNA/cDNA for ACSL6 Gene
- (6) REFSEQ mRNAs :
- (13) Additional mRNA sequences :
- (146) Selected AceView cDNA sequences:
- (21) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ACSL6 Gene
- Acyl-CoA synthetase long-chain family member 6:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for ACSL6
-
Santa Cruz Biotechnology (SCBT) CRISPR for ACSL6
- GenScript: Design CRISPR guide RNA sequences for ACSL6
miRNA Products
- Search ViGene Biosciences for ACSL6
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ACSL6
- Browse OriGene Inhibitory RNA Products For ACSL6
Clone Products
- Sino Biological Human cDNA Clone for ACSL6
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ACSL6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACSL6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP4: |
Expression for ACSL6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Blood (Hematopoietic System)
- Erythroblasts Hematopoietic Bone Marrow
-
Epithelial Cells
- Mature Choroid Plexus Cells Choroid Plexus
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for ACSL6 Gene
This gene is overexpressed in Brain - Cerebellum (x5.5), Brain - Cerebellar Hemisphere (x5.4), Brain - Frontal Cortex (BA9) (x5.1), Brain - Anterior cingulate cortex (BA24) (x4.7), and Brain - Cortex (x4.0).
This gene is overexpressed in Retina (25.1), Frontal cortex (20.3), and Testis (8.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ACSL6 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ACSL6 Gene:
ACSL6SOURCE GeneReport for Unigene cluster for ACSL6 Gene:
Hs.14945mRNA Expression by UniProt/SwissProt for ACSL6 Gene:
Q9UKU0-ACSL6_HUMAN
Tissue specificity:
Expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derived from fetal liver, hemopoietic stem cells from cord blood, bone marrow and brain.
Evidence on tissue expression from TISSUES for ACSL6 Gene
- Nervous system(4.8)
- Bone marrow(4.2)
- Liver(3)
- Heart(2.3)
- Muscle(2.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for ACSL6
-
OriGene qPCR primer pairs for ACSL6
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ACSL6 Gene
Orthologs for ACSL6 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ACSL6 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ACSL6 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | ACSL6 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Acsl6 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Acsl6 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ACSL6 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ACSL6 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ACSL6 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ACSL6 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | acsl6 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | acsl6 35 |
|
OneToOne | |
| acsl1a 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | CG3961 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | acs-13 35 |
|
ManyToMany | |
| acs-5 35 |
|
ManyToMany | |||
| acs-15 35 |
|
ManyToMany | |||
| R09E10.4 35 |
|
ManyToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | FAA2 35 |
|
OneToMany | |
| barley (Hordeum vulgare) |
Liliopsida | Hv.10667 34 |
|
||
| wheat (Triticum aestivum) |
Liliopsida | Ta.27153 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
ManyToMany | |
| CSA.10659 35 |
|
ManyToMany |
- Species where no ortholog for ACSL6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Paralogs for ACSL6 Gene
(6) SIMAP similar genes for ACSL6 Gene using alignment to 10 proteins:
Variants for ACSL6 Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000084300 | -- | 131,984,638(+) | AGGGT(A/G)GACAG | intron-variant | |
| rs1000084358 | -- | 131,952,511(+) | TCTAG(A/G)CTACA | utr-variant-3-prime | |
| rs1000293556 | -- | 132,010,223(+) | GGGAA(G/T)TGTCC | intron-variant | |
| rs1000321415 | -- | 131,980,687(+) | TCATG(C/T)TTTGA | intron-variant | |
| rs1000331249 | -- | 132,007,541(+) | CAGCT(C/T)TTACA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv25745 | CNV | gain | 19812545 |
| esv3307926 | CNV | mobile element insertion | 20981092 |
| esv3409875 | CNV | insertion | 20981092 |
| esv3415163 | CNV | insertion | 20981092 |
| nsv1024604 | CNV | gain | 25217958 |
| nsv1031854 | CNV | gain | 25217958 |
| nsv1131914 | CNV | deletion | 24896259 |
Residual Variation Intolerance Score:
12.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.14;
38.90% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ACSL6 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ACSL6
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACSL6 Gene
Disorders for ACSL6 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| myelodysplastic syndrome |
|
|
| chronic intestinal vascular insufficiency |
|
|
| schizophrenia |
|
|
Search ACSL6 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
ACSL6_HUMAN- Note=A chromosomal aberration involving ACSL6 may be a cause of acute eosinophilic leukemia (AEL). Translocation t(5;12)(q31;p13) with ETV6. {ECO:0000269 PubMed:10502316}.
- Note=A chromosomal aberration involving ACSL6 may be a cause of acute myelogenous leukemia with eosinophilia. Translocation t(5;12)(q31;p13) with ETV6. {ECO:0000269 PubMed:10502316}.
- Note=A chromosomal aberration involving ACSL6 may be a cause of myelodysplastic syndrome with basophilia. Translocation t(5;12)(q31;p13) with ETV6. {ECO:0000269 PubMed:10502316}.
Relevant External Links for ACSL6
No data available for Genatlas for ACSL6 Gene
Publications for ACSL6 Gene
- Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13). (PMID: 10502316) Yagasaki F. … Hirashima K. (Genes Chromosomes Cancer 1999) 2 3 4 22 64
- Identification and molecular characterization of acyl-CoA synthetase in human red cells and erythroid precursor. (PMID: 10548543) Malhotra K.T. … Kuypers F.A. (Biochem. J. 1999) 2 3 4 22 64
- Acyl-CoA synthetase long-chain family member 6 is associated with premature ovarian failure. (PMID: 18555221) Kang H. … Kwack K. (Fertil. Steril. 2009) 3 22 46 64
- Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains. (PMID: 16834775) Soupene E. … Kuypers F.A. (BMC Mol. Biol. 2006) 3 4 22 64
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
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- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for ACSL6: See all 41
- Search antibodies-online for kits
- antibodies-online Proteins for ACSL6: See all 7
- Search antibodies-online for peptides
- GeneTex ACSL6 antibody for ACSL6
- Search GeneTex for Proteins for ACSL6
- Cyagen custom Knockout/knockin (KOKI) mouse models for ACSL6
- VectorBuilder custom plasmid, inducible vectors for ACSL6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACSL6
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ACSL6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer