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Aliases for ACRC Gene

Aliases for ACRC Gene

  • Acidic Repeat Containing 2 3
  • Acidic Repeat-Containing Protein 3
  • Putative Nuclear Protein 3
  • NAAR1 3

External Ids for ACRC Gene

Previous GeneCards Identifiers for ACRC Gene

  • GC0XP066974
  • GC0XP068275
  • GC0XP069031
  • GC0XP069665
  • GC0XP070581
  • GC0XP070714
  • GC0XP070797
  • GC0XP064613

Summaries for ACRC Gene

GeneCards Summary for ACRC Gene

ACRC (Acidic Repeat Containing) is a Protein Coding gene. Diseases associated with ACRC include appendix adenocarcinoma.

Gene Wiki entry for ACRC Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACRC Gene

Genomics for ACRC Gene

Regulatory Elements for ACRC Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ACRC Gene

Start:
71,577,990 bp from pter
End:
71,613,590 bp from pter
Size:
35,601 bases
Orientation:
Plus strand

Genomic View for ACRC Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ACRC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ACRC Gene

Proteins for ACRC Gene

  • Protein details for ACRC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96QF7-ACRC_HUMAN
    Recommended name:
    Acidic repeat-containing protein
    Protein Accession:
    Q96QF7
    Secondary Accessions:
    • B9EG62

    Protein attributes for ACRC Gene

    Size:
    691 amino acids
    Molecular mass:
    76112 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ACRC Gene

Proteomics data for ACRC Gene at MOPED

Post-translational modifications for ACRC Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ACRC Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ACRC Gene

Domains for ACRC Gene

Protein Domains for ACRC Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ACRC Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96QF7

UniProtKB/Swiss-Prot:

ACRC_HUMAN :
  • Q96QF7
Domain:
  • Contains 1 SprT-like domain.
Family:
  • Belongs to the serine-aspartate repeat-containing protein (SDr) family.
genes like me logo Genes that share domains with ACRC: view

No data available for Gene Families for ACRC Gene

Function for ACRC Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ACRC Gene

Localization for ACRC Gene

Subcellular locations from UniProtKB/Swiss-Prot for ACRC Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ACRC Gene COMPARTMENTS Subcellular localization image for ACRC gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for ACRC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ACRC: view

Pathways for ACRC Gene

SuperPathways for ACRC Gene

No Data Available

Interacting Proteins for ACRC Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000362799%0d%0a9606.ENSP00000354497%0d%0a
Selected Interacting proteins: ENSP00000362799 for ACRC Gene via STRING

Symbol External ID(s) Details
FAN1

Gene Ontology (GO) - Biological Process for ACRC Gene

None

No data available for Pathways by source for ACRC Gene

Transcripts for ACRC Gene

mRNA/cDNA for ACRC Gene

Unigene Clusters for ACRC Gene

Acidic repeat containing:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ACRC

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ACRC
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ACRC Gene

No ASD Table

Relevant External Links for ACRC Gene

GeneLoc Exon Structure for
ACRC
ECgene alternative splicing isoforms for
ACRC

Expression for ACRC Gene

mRNA expression in normal human tissues for ACRC Gene

mRNA differential expression in normal tissues according to GTEx for ACRC Gene

This gene is overexpressed in Testis (4.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ACRC Gene

SOURCE GeneReport for Unigene cluster for ACRC Gene Hs.135167

mRNA Expression by UniProt/SwissProt for ACRC Gene

Q96QF7-ACRC_HUMAN
Tissue specificity: Detected in skeletal muscle, liver, kidney, pancreas, heart, lung and brain.
genes like me logo Genes that share expressions with ACRC: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for ACRC Gene

Orthologs for ACRC Gene

This gene was present in the common ancestor of animals.

Orthologs for ACRC Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ACRC 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ACRC 36
  • 47 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ACRC 36
  • 30 (a)
OneToOne
chicken
(Gallus gallus)
Aves ACRC 36
  • 27 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ACRC 36
  • 37 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii acrc 36
  • 23 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG14814 36
  • 14 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea ZK328.4 36
  • 15 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5183 36
  • 31 (a)
OneToOne
Species with no ortholog for ACRC:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ACRC Gene

ENSEMBL:
Gene Tree for ACRC (if available)
TreeFam:
Gene Tree for ACRC (if available)

Paralogs for ACRC Gene

Pseudogenes.org Pseudogenes for ACRC Gene

genes like me logo Genes that share paralogs with ACRC: view

No data available for Paralogs for ACRC Gene

Variants for ACRC Gene

Sequence variations from dbSNP and Humsavar for ACRC Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2280962 - 71,612,891(+) GGACA(C/T)CAGCC reference, missense
rs2280963 -- 71,613,541(+) AAACT(A/G)TCTGA utr-variant-3-prime
rs3810672 -- 71,611,057(+) CCAGC(A/G)GTAGC intron-variant
rs3810673 -- 71,611,269(+) TGGCT(G/T)TTGAG intron-variant
rs4844298 -- 71,584,094(+) ccacc(C/T)gcctc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ACRC Gene

Variant ID Type Subtype PubMed ID
esv1584074 OTHER Inversion 17803354
esv33082 CNV Loss 17666407
esv27144 CNV Gain 19812545
nsv6954 CNV Insertion 18451855
esv2740214 CNV Deletion 23290073

Relevant External Links for ACRC Gene

HapMap Linkage Disequilibrium report
ACRC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACRC Gene

Disorders for ACRC Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for ACRC Gene including...

Search for ACRC Gene in MalaCards »

(1) University of Copenhagen DISEASES for ACRC Gene

genes like me logo Genes that share disorders with ACRC: view

No data available for UniProtKB/Swiss-Prot for ACRC Gene

Publications for ACRC Gene

  1. ACRC codes for a novel nuclear protein with unusual acidic repeat tract and maps to DYT3 (dystonia parkinsonism) critical interval in xq13.1. (PMID: 11714101) Nolte D. … Mueller U. (Neurogenetics 2001) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ACRC Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ACRC
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat
  • Predesigned siRNA for gene silencing in human,mouse,rat for ACRC
  • Block miRNA regulation of ACRC using miScript Target Protectors

Sources for ACRC Gene

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