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Aliases for ACRC Gene

Aliases for ACRC Gene

  • Acidic Repeat Containing 2 3 5
  • Acidic Repeat-Containing Protein 3
  • Putative Nuclear Protein 3
  • NAAR1 3

External Ids for ACRC Gene

Previous GeneCards Identifiers for ACRC Gene

  • GC0XP066974
  • GC0XP068275
  • GC0XP069031
  • GC0XP069665
  • GC0XP070581
  • GC0XP070714
  • GC0XP070797
  • GC0XP064613

Summaries for ACRC Gene

GeneCards Summary for ACRC Gene

ACRC (Acidic Repeat Containing) is a Protein Coding gene. Diseases associated with ACRC include Appendix Adenocarcinoma.

Gene Wiki entry for ACRC Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACRC Gene

Genomics for ACRC Gene

Regulatory Elements for ACRC Gene

Enhancers for ACRC Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ACRC on UCSC Golden Path with GeneCards custom track

Genomic Location for ACRC Gene

71,578,024 bp from pter
71,613,583 bp from pter
35,560 bases
Plus strand

Genomic View for ACRC Gene

Genes around ACRC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ACRC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ACRC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ACRC Gene

Proteins for ACRC Gene

  • Protein details for ACRC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Acidic repeat-containing protein
    Protein Accession:
    Secondary Accessions:
    • B9EG62

    Protein attributes for ACRC Gene

    691 amino acids
    Molecular mass:
    76112 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ACRC Gene

Post-translational modifications for ACRC Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ACRC Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ACRC Gene

Domains & Families for ACRC Gene

Protein Domains for ACRC Gene


Suggested Antigen Peptide Sequences for ACRC Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 SprT-like domain.
  • Belongs to the serine-aspartate repeat-containing protein (SDr) family.
  • Contains 1 SprT-like domain.
  • Belongs to the serine-aspartate repeat-containing protein (SDr) family.
genes like me logo Genes that share domains with ACRC: view

No data available for Gene Families for ACRC Gene

Function for ACRC Gene

genes like me logo Genes that share phenotypes with ACRC: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ACRC Gene

Localization for ACRC Gene

Subcellular locations from UniProtKB/Swiss-Prot for ACRC Gene

Subcellular locations from

Jensen Localization Image for ACRC Gene COMPARTMENTS Subcellular localization image for ACRC gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ACRC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ACRC: view

Pathways & Interactions for ACRC Gene

SuperPathways for ACRC Gene

No Data Available

Interacting Proteins for ACRC Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000362799 for ACRC Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for ACRC Gene


No data available for Pathways by source and SIGNOR curated interactions for ACRC Gene

Drugs & Compounds for ACRC Gene

(1) Drugs for ACRC Gene - From: ClinicalTrials

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
mometasone furoate Pharma Synthetic corticosteroid; anti-inflammatory agent 162

(3) Additional Compounds for ACRC Gene - From:

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with ACRC: view

Transcripts for ACRC Gene

mRNA/cDNA for ACRC Gene

Unigene Clusters for ACRC Gene

Acidic repeat containing:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ACRC Gene

No ASD Table

Relevant External Links for ACRC Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ACRC Gene

mRNA expression in normal human tissues for ACRC Gene

mRNA differential expression in normal tissues according to GTEx for ACRC Gene

This gene is overexpressed in Testis (x4.1).

Protein differential expression in normal tissues from HIPED for ACRC Gene

This gene is overexpressed in Testis (41.2), Ovary (14.0), and Fetal ovary (7.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ACRC Gene

Protein tissue co-expression partners for ACRC Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ACRC Gene:


SOURCE GeneReport for Unigene cluster for ACRC Gene:


mRNA Expression by UniProt/SwissProt for ACRC Gene:

Tissue specificity: Detected in skeletal muscle, liver, kidney, pancreas, heart, lung and brain.
genes like me logo Genes that share expression patterns with ACRC: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for ACRC Gene

Orthologs for ACRC Gene

This gene was present in the common ancestor of animals.

Orthologs for ACRC Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ACRC 35
  • 47 (a)
(Monodelphis domestica)
Mammalia ACRC 35
  • 30 (a)
(Pan troglodytes)
Mammalia ACRC 35
  • 97 (a)
(Gallus gallus)
Aves ACRC 35
  • 27 (a)
(Anolis carolinensis)
Reptilia ACRC 35
  • 37 (a)
(Danio rerio)
Actinopterygii acrc 35
  • 23 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14814 35
  • 14 (a)
(Caenorhabditis elegans)
Secernentea ZK328.4 35
  • 15 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5183 35
  • 31 (a)
Species where no ortholog for ACRC was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ACRC Gene

Gene Tree for ACRC (if available)
Gene Tree for ACRC (if available)

Paralogs for ACRC Gene Pseudogenes for ACRC Gene

genes like me logo Genes that share paralogs with ACRC: view

No data available for Paralogs for ACRC Gene

Variants for ACRC Gene

Sequence variations from dbSNP and Humsavar for ACRC Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs2280962 - 71,612,891(+) GGACA(C/T)CAGCC reference, missense
rs10217999 - 71,605,675(+) GAAGC(A/G)TGGGC reference, missense
rs747762224 -- 71,603,927(+) CGACG(-/ACA)AGAGT cds-indel
rs747815870 -- 71,582,462(+) AAAAG(C/T)TTGAT intron-variant
rs747817337 -- 71,597,923(+) CTCTC(-/TTG)TTTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ACRC Gene

Variant ID Type Subtype PubMed ID
esv1584074 OTHER inversion 17803354
esv27144 CNV gain 19812545
esv2740214 CNV deletion 23290073
esv33082 CNV loss 17666407
nsv6954 CNV insertion 18451855

Variation tolerance for ACRC Gene

Residual Variation Intolerance Score: 20.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.10; 38.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ACRC Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACRC Gene

Disorders for ACRC Gene

MalaCards: The human disease database

(1) MalaCards diseases for ACRC Gene - From: DISEASES

Disorder Aliases PubMed IDs
appendix adenocarcinoma
  • mucinous adenocarcinoma
- elite association - COSMIC cancer census association via MalaCards
Search ACRC in MalaCards View complete list of genes associated with diseases

Relevant External Links for ACRC

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ACRC: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ACRC Gene

Publications for ACRC Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. ACRC codes for a novel nuclear protein with unusual acidic repeat tract and maps to DYT3 (dystonia parkinsonism) critical interval in xq13.1. (PMID: 11714101) Nolte D. … Mueller U. (Neurogenetics 2001) 3 4 65
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 65
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for ACRC Gene

Sources for ACRC Gene

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