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ACPT Gene

protein-coding   GIFtS: 52
GCID: GC19P051293

Acid Phosphatase, Testicular

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Acid Phosphatase, Testicular1 2
EC 3.1.3.23 8
Testicular Acid Phosphatase2

External Ids:    HGNC: 143761   Entrez Gene: 936502   Ensembl: ENSG000001425137   OMIM: 6063625   UniProtKB: Q9BZG23   

Export aliases for ACPT gene to outside databases

Previous GC identifers: GC19P051922 GC19P051654 GC19P055969 GC19P055985 GC19P047628


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ACPT Gene:
Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is
up-regulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. This gene exhibits
a lower level of expression in testicular cancer tissues than in normal tissues. The protein encoded by this gene
has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants
have been described, but their biological validity has not been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for ACPT Gene:
ACPT (acid phosphatase, testicular) is a protein-coding gene. Diseases associated with ACPT include testicular cancer, and prostate cancer. GO annotations related to this gene include acid phosphatase activity. An important paralog of this gene is ACPP.

UniProtKB/Swiss-Prot: PPAT_HUMAN, Q9BZG2
Function: Dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic
cleavage




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NC_018930.2  NT_011109.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the ACPT gene promoter:
         AP-4   LCR-F1   Meis-1b   E47   ARP-1   STAT3   Meis-1a   TGIF   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidACPT promoter sequence
   Search Chromatin IP Primers for ACPT

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ACPT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.4   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.33

ACPT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACPT gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P051293:  view genomic region     (about GC identifiers)

Start:
51,293,672 bp from pter      End:
51,298,481 bp from pter
Size:
4,810 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PPAT_HUMAN, Q9BZG2 (See protein sequence)
Recommended Name: Testicular acid phosphatase precursor  
Size: 426 amino acids; 46090 Da
Subunit: Homodimer (Probable)
Secondary accessions: C0H3P7 Q9BZG3 Q9BZG4
Alternative splicing: 3 isoforms:  Q9BZG2-1   Q9BZG2-2   Q9BZG2-3   

Explore the universe of human proteins at neXtProt for ACPT: NX_Q9BZG2

Explore proteomics data for ACPT at MOPED

Post-translational modifications: 

  • Glycosylated (Probable)1
  • Glycosylation2 at Asn191, Asn269, Asn330, Asn339
  • Modification sites at PhosphoSitePlus
  • 2 DME Specific Peptides for ACPT (Q9BZG2)
     ANLAGLFP  RSTDFDRTL 


    See ACPT Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_149059.1  
    ENSEMBL proteins: 
     ENSP00000270593   ENSP00000270594  

    ACPT Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for ACPT
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ACPT
    GenScript Custom Purified and Recombinant Proteins Services for ACPT
    Novus Biologicals ACPT Protein
    Novus Biologicals ACPT Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ACPT

    ACPT Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals ACPT Antibodies
    Abcam antibodies for ACPT
    Cloud-Clone Corp. Antibodies for ACPT
    Search ThermoFisher Antibodies for ACPT
    LSBio Antibodies in human, mouse, rat for ACPT

    ACPT Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ACPT
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ACPT
    Cloud-Clone Corp. CLIAs for ACPT


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR000560 His_Pase_superF_clade-2

    Graphical View of Domain Structure for InterPro Entry Q9BZG2

    ProtoNet protein and cluster: Q9BZG2

    1 Blocks protein domain: IPB000560 Histidine acid phosphatase

    UniProtKB/Swiss-Prot: PPAT_HUMAN, Q9BZG2
    Similarity: Belongs to the histidine acid phosphatase family


    ACPT for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PPAT_HUMAN, Q9BZG2
    Function: Dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic
    cleavage
    Catalytic activity: A phosphate monoester + H(2)O = an alcohol + phosphate
    Induction: Up-regulated by mibolerone (a synthetic androgen) and dihydrotestosterone (DHT) and is down-regulated
    by estrogen and progestin

         Enzyme Number (IUBMB): EC 3.1.3.21 2

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003993acid phosphatase activity IEA--
         
    ACPT for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ACPT
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ACPT

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ACPT
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ACPT

    miRNA
    Products:
        
    miRTarBase miRNAs that target ACPT:
    hsa-mir-484 (MIRT042280)

    Block miRNA regulation of human, mouse, rat ACPT using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ACPT:
    hsa-miR-3147
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ACPT
    Predesigned siRNA for gene silencing in human, mouse, rat ACPT

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ACPT

    Clone
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    OriGene clones in human, mouse for ACPT (see all 4)
    OriGene ORF clones in mouse, rat for ACPT
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ACPT (NM_033068)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACPT
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACPT

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for ACPT 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACPT


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PPAT_HUMAN, Q9BZG2: Membrane; Single-pass type I membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    chloroplast2
    endoplasmic reticulum2
    plasma membrane2
    extracellular1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    ACPT for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ACPT About    
    See pathways by source

    SuperPathContained pathways About
    1Riboflavin metabolism
    Riboflavin metabolism

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Kegg Pathway  (Kegg details for ACPT):
        Riboflavin metabolism


    ACPT for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ACPT
    Interactions:

        Search GeneGlobe Interaction Network for ACPT

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for ACPT (ENSP000002705934) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENPP1ENSP000003542384STRING: ENSP00000354238
    ENPP3ENSP000003502654STRING: ENSP00000350265
    FLAD1ENSP000002921804STRING: ENSP00000292180
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ACPT (PPAT)

    Selected HMDB Compounds for ACPT (see all 13)    About this table
    CompoundSynonyms CAS #PubMed Ids
    1-Butanol1-Butanol (see all 10)71-36-3--
    1-Hexanol1-Hexyl alcohol (see all 30)111-27-3--
    1-Pentanol1-Pentol (see all 34)71-41-0--
    4-Nitrophenol1-Hydroxy-4-nitrobenzene (see all 8)100-02-7--
    Ethanol1-Hydroxyethane (see all 57)64-17-5--
    Flavin MononucleotideFMN (see all 19)146-17-8--
    Isobutanol1-Hydroxymethylpropane (see all 18)78-83-1--
    Isopropyl alcohol2-Propanol (see all 12)67-63-0--
    PhosphateNFB Orthophosphate (see all 13)14265-44-2--
    Propyl alcohol1-Hydroxypropane (see all 17)71-23-8--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ACPT gene (4 alternative transcripts): 
    NM_033068.2  NM_080789.1  NM_080790.1  NM_080791.1  

    Unigene Cluster for ACPT:

    Acid phosphatase, testicular
    Hs.293394  [show with all ESTs]
    Unigene Representative Sequence: NM_033068
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000270593(uc002pta.1) ENST00000270594
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ACPT using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ACPT:
    hsa-miR-3147
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ACPT
    Predesigned siRNA for gene silencing in human, mouse, rat ACPT
    Clone
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    OriGene clones in human, mouse for ACPT (see all 4)
    OriGene ORF clones in mouse, rat for ACPT
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ACPT (NM_033068)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACPT
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACPT
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ACPT
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ACPT
      QuantiTect SYBR Green Assays in human, mouse, rat ACPT
      QuantiFast Probe-based Assays in human, mouse, rat ACPT

    1 DOTS entry:

    DT.432968 

    9 AceView cDNA sequences:

    NM_080791 NM_033068 NM_080789 NM_080790 AA868001 AA861388 BX281038 AA861459 
    AA983914 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ACPT expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATGCTCAGT
    ACPT Expression
    About this image

    ACPT Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ACPT Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.293394

    UniProtKB/Swiss-Prot: PPAT_HUMAN, Q9BZG2
    Tissue specificity: Expressed mainly in the testis. Also expressed in the brain where they are enriched at the
    postsynaptic sites. Expressed at lower levels in the trachea, prostate, bone marrow, spinal cord, colon, fetal
    brain, heart, thymus, fetal liver, spleen, leukocytes, ovary, small intestine, pancreas and skeletal muscle.
    Expression is significantly lower in testicular cancer tissues than in normal testicular tissues. Isoform 3 is
    expressed in the testis, trachea, prostate and bone marrow

        Custom PCR Arrays for ACPT
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    QuantiFast Probe-based Assays in human, mouse, rat ACPT
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACPT

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ACPT gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Acpt1 , 5 acid phosphatase, testicular1, 5 83.29(n)1
    86.15(a)1
      7 (28.77 cM)5
    1005039911  NM_001195034.11  NP_001181963.11 
     442521485 
    lizard
    (Anolis carolinensis)
    Reptilia ACPT6
    acid phosphatase, testicular
    49(a)
    1 ↔ 1
    GL343287.1(355559-364380)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004948561 testicular acid phosphatase homolog 59.57(n)
    56.21(a)
      100494856  XM_002934647.2  XP_002934693.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG94496
    Acph-16
    (see all 5)
    Acid phosphatase 1
    (see all 5)
    28(a)
    28(a)
    (see all 5)
    many ↔ many
    many ↔ many
    (see all 5)
    3L(19485153-19490823)
    3R(25816861-25819130)
    worm
    (Caenorhabditis elegans)
    Secernentea T13B5.33 acid phosphatase 33(a)
    (best of 3)
      II(1097327-1099531)   --


    ENSEMBL Gene Tree for ACPT (if available)
    TreeFam Gene Tree for ACPT (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ACPT gene
    ACPP2  ACP62  ACP22  
    2 SIMAP similar genes for ACPT using alignment to 1 protein entry:     PPAT_HUMAN:
    ACPP    ACP2

    ACPT for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ACPT (see all 274)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1851947721,2
    --51291735(+) GCCACG/TGAGTG 1 -- us2k10--------
    rs789087071,2
    C,F--51291764(+) CAATAC/TATCAG 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1179118231,2
    C,F--51291800(+) AGGGGC/ATAGAA 1 -- us2k11Minor allele frequency- A:0.01NA 120
    rs561645471,2
    C,F--51291947(+) ACTCAT/CGTGAT 1 -- us2k19Minor allele frequency- C:0.43WA NA CSA EA 370
    rs1896969801,2
    --51291972(+) CTCTTC/GAGTAG 1 -- us2k10--------
    rs1131757291,2
    F--51291975(+) TTGAGC/TAGCTG 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1506921841,2
    --51291989(+) CTACAA/GGCAGA 1 -- us2k10--------
    rs595243801,2
    C,F--51292007(+) ATACCA/GTGCCT 1 -- us2k18Minor allele frequency- G:0.44WA NA CSA EA 368
    rs124631481,2
    H--51292025(+) ttttgG/Tttatc 1 -- us2k1 tfbs30--------
    rs778552441,2
    C,F--51292032(+) TATCTT/CTTATA 1 -- us2k11Minor allele frequency- C:0.09WA 118

    HapMap Linkage Disequilibrium report for ACPT (51293672 - 51298481 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ACPT:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv3977n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ACPT
    DNA2.0 Custom Variant and Variant Library Synthesis for ACPT

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606362    OMIM disorders: --

    3 diseases for ACPT:    
    About MalaCards
    testicular cancer    prostate cancer    prostatitis


    ACPT for disorders           About GeneDecksing


    Export disorders for ACPT gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ACPT gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ACPT)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of a novel human acid phosphatase gene (ACPT) that is highly expressed in the testis. (PubMed id 11414767)1, 2, 3, 9 Yousef G.M.... Diamandis E.P. (Genomics 2001)
    2. Regulation of ErbB4 phosphorylation and cleavage by a novel histidine acid phosphatase. (PubMed id 15219672)1, 2, 9 Fleisig H.... Vincent S.R. (Neuroscience 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 93650 HGNC: 14376 AceView: ACPT Ensembl:ENSG00000142513 euGenes: HUgn93650
    ECgene: ACPT Kegg: 93650 H-InvDB: ACPT

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ACPT Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ACPT Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ACPT gene:
    Search GeneIP for patents involving ACPT

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ACPT  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for ACPT  
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     OriGene Custom Antibody Services for ACPT   OriGene Custom Protein Services for ACPT  

     
     
     Block miRNA regulation of human, mouse, rat ACPT using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ACPT
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ACPT Predesigned siRNA for gene silencing in human, mouse, rat ACPT
     QuantiFast Probe-based Assays in human, mouse, rat ACPT QuantiTect SYBR Green Assays in human, mouse, rat ACPT
     Custom PCR Arrays for ACPT Search Chromatin IP Primers for ACPT
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ACPT  Search GeneGlobe Interaction Network for ACPT
     Regulatory tfbs in ACPT promoter
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     Search Tocris compounds for ACPT (PPAT)
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     Novus Tissue Slides
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     Browse ESI BIO Cell Lines and PureStem Progenitors for ACPT
     Gene Synthesis
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     Browse SwitchGear 3'UTR luciferase reporter plasmids for ACPT
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     Search ThermoFisher Antibodies for ACPT
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACPT
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ACPT
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     LSBio Antibodies in human, mouse, rat for ACPT
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     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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