External Ids for ACPT Gene
Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is up-regulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. This gene exhibits a lower level of expression in testicular cancer tissues than in normal tissues. The protein encoded by this gene has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for ACPT Gene
ACPT (Acid Phosphatase, Testicular) is a Protein Coding gene. Diseases associated with ACPT include prostate cancer and testicular cancer. Among its related pathways are Riboflavin metabolism. GO annotations related to this gene include acid phosphatase activity. An important paralog of this gene is ACPP.
UniProtKB/Swiss-Prot for ACPT Gene
Dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic cleavage.