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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ACPL2 Gene

protein-coding   GIFtS: 52
GCID: GC03P140950

acid phosphatase-like 2
 Explore 1 disease affiliated with
ACPL2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ACPL2    

Aliases
for ACPL2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Acid Phosphatase-Like 21 2
EC 3.1.3.23 8
FLJ237511
Acid Phosphatase-Like Protein 22

External Ids:    HGNC: 263031   Entrez Gene: 923702   Ensembl: ENSG000001558937   UniProtKB: Q8TE993   

Export aliases for ACPL2 gene to outside databases

Previous GC identifers: GC03P142433 GC03P138325


Summaries
for ACPL2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for ACPL2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ACPL2 gene promoter:
         AML1a   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   CUTL1   POU3F2   FOXC1   GATA-6   POU2F1   POU2F1a   Msx-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ACPL2 promoter sequence
   Search SABiosciences Chromatin IP Primers for ACPL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACPL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q23   Ensembl cytogenetic band:  3q23   HGNC cytogenetic band: 3q23

ACPL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACPL2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P140950:  view genomic region     (about GC identifiers)

Start:
 140,947,568 bp from pter      End:
 141,013,748 bp from pter
Size:
 66,181 bases      Orientation:
 plus strand

Proteins
for ACPL2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ACPL2_HUMAN, Q8TE99 (See protein sequence)
Recommended Name: Acid phosphatase-like protein 2 precursor  
Size: 480 amino acids; 55240 Da
Subcellular location: Secreted (Potential)
Secondary accessions: D3DNF5 Q49AJ2
Alternative splicing: 2 isoforms:  Q8TE99-1   Q8TE99-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ACPL2: NX_Q8TE99

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8TE99

    • 4 DME Specific Peptides for ACPL2 (Q8TE99)
     IPKTKRP  EHFKVIKTHQ  EARFPRFAARL  GELTQTGVVQHL 

    ACPL2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001032249.1  NP_689495.1  

    ENSEMBL proteins: 
     ENSP00000421271   ENSP00000425264   ENSP00000286353   ENSP00000422558   ENSP00000376733  
     ENSP00000426956   ENSP00000426348   ENSP00000423702   ENSP00000426877   ENSP00000422901  
     ENSP00000376731  

    Human Recombinant Protein Products: 
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    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate (see all 2): ACPL2
    OriGene Custom Protein Services for ACPL2 
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    Novus Biologicals ACPL2 Lysates
    Sino Biological Recombinant Protein for ACPL2
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ACPL2

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--


    ACPL2 for ontologies           About GeneDecksing



    ACPL2 Antibody Products: 
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    Uscn ELISAs and CLIAs for ACPL2

    Protein Domains /
    Families
    for ACPL2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ACPL2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR000560 His_Pase_superF_clade-2

    Graphical View of Domain Structure for InterPro Entry Q8TE99

    ProtoNet protein and cluster: Q8TE99

    1 Blocks protein family: IPB000560 Histidine acid phosphatase

    UniProtKB/Swiss-Prot: ACPL2_HUMAN, Q8TE99
    Similarity: Belongs to the histidine acid phosphatase family


    Function
    for ACPL2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ACPL2_HUMAN, Q8TE99
    Catalytic activity: A phosphate monoester + H(2)O = an alcohol + phosphate

    Enzyme Number (IUBMB): EC 3.1.3.21 2

    miRNA
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    hsa-mir-1 (MIRT002817)

    OriGene 3'-UTR Clone (see all 2): ACPL2
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ACPL2
    8/62 QIAGEN miScript miRNA Assays for microRNAs that regulate ACPL2 (see all 62):
    hsa-miR-3685 hsa-miR-302d hsa-miR-520e hsa-miR-106a hsa-miR-548k hsa-miR-29a hsa-miR-301a hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmid: ACPL2 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ACPL2 (see all 7)
    OriGene shRNA RFP: ACPL2
    OriGene siRNA: ACPL2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ACPL2

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for ACPL2

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACPL2 (see all 4)
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    GenScript: all cDNA clones in your preferred vector (see all 2): ACPL2 (NM_152282)
    Sino Biological Human cDNA Clone for ACPL2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACPL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACPL2 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for ACPL2
    Search LifeMap BioReagents cell lines for ACPL2

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACPL2

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003993acid phosphatase activity IEA--


    ACPL2 for ontologies           About GeneDecksing


    5 GenomeRNAi human phenotypes for ACPL2:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e  Decreased viability of wild-ty 
     Increased gamma-H2AX phosphory 

    Animal Models:
         Mouse knock-out Acpl2tm1Lex for ACPL2
         1 MGI phenotypic allele for Acpl2 (no phenotypes)

    ACPL2 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for ACPL2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1NAD phosphorylation and dephosphorylation
    		NAD phosphorylation and dephosphorylation1.00
    2Nicotinate metabolism
    		NAD salvage pathway II0.18


    2 BioSystems Pathways for ACPL2 
        NAD salvage pathway II
    NAD phosphorylation and dephosphorylation


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ACPL2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for ACPL2 (ENSP000002863534) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NADKENSP000003416794STRING: ENSP00000341679
    NNTENSP000002646634STRING: ENSP00000264663
    NUDT12ENSP000002307924STRING: ENSP00000230792
    About this table

    Drugs & Compounds
    for ACPL2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ACPL2

    7 HMDB Compounds for ACPL2    About this table
    CompoundSynonyms CAS #PubMed Ids
    1-Butanol1-Butanol (see all 10)71-36-3--
    1-Hexanol1-Hexyl alcohol (see all 30)111-27-3--
    1-Pentanol1-Pentol (see all 34)71-41-0--
    Ethanol1-Hydroxyethane (see all 57)64-17-5--
    Isobutanol1-Hydroxymethylpropane (see all 18)78-83-1--
    Isopropyl alcohol2-Propanol (see all 12)67-63-0--
    Propyl alcohol1-Hydroxypropane (see all 17)71-23-8--
    Search CenterWatch for drugs/clinical trials and news about ACPL2 

    Transcripts
    for ACPL2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ACPL2 gene (2 alternative transcripts): 
    NM_001037172.1  NM_152282.3  

    Unigene Cluster for ACPL2:

    Acid phosphatase-like 2
    Hs.657887  [show with all ESTs]
    Unigene Representative Sequence: BC036701
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000505013 ENST00000514880 ENST00000286353(uc003etv.3 uc011bna.2)
    ENST00000502783 ENST00000393010(uc003etu.3 uc011bnb.2) ENST00000511968
    ENST00000514680 ENST00000513528 ENST00000505502 ENST00000513007 ENST00000512457
    ENST00000504264 ENST00000508812 ENST00000514263 ENST00000393007

    miRNA
    Products:             		 OriGene 3'-UTR Clone (see all 2): ACPL2
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ACPL2
    8/62 QIAGEN miScript miRNA Assays for microRNAs that regulate ACPL2 (see all 62):
    hsa-miR-3685 hsa-miR-302d hsa-miR-520e hsa-miR-106a hsa-miR-548k hsa-miR-29a hsa-miR-301a hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmid: ACPL2 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ACPL2 (see all 7)
    OriGene shRNA RFP: ACPL2
    OriGene siRNA: ACPL2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ACPL2
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACPL2 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): ACPL2 (NM_152282)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACPL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACPL2 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ACPL2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ACPL2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ACPL2

    Additional cDNA sequence: 

    AK074331.1 AK296292.1 AK297790.1 AK316121.1 AL137529.1 AY358460.1 BC035834.1 BC036701.1 
    BX647621.1 

    11 DOTS entries:

    DT.441371  DT.95102985  DT.101961832  DT.75145147  DT.100776711  DT.100653995  DT.102887  DT.120898482 
    DT.95164751  DT.95216156  DT.97840654 

    24/109 AceView cDNA sequences (see all 109):

    BQ772332 BQ721935 BX114498 BQ022307 C02599 AA398161 AK074331 BQ771835 
    BQ000536 AA588462 AI459978 BM716853 BQ575661 CN479919 AL699456 AI214440 
    AA777284 AL137529 BQ025005 BI830132 AI362309 AW451826 CD637673 BF792731 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ACPL2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
    SP1:              -                 -           -     -                                 
    SP2:              -     -     -     -           -     -                                 
    SP3:                                                                                    
    SP4:              -                                                                     
    SP5:                    -     -     -                                                   


    ECgene alternative splicing isoforms for ACPL2

    Expression
    for ACPL2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ACPL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTACTATGTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ACPL2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BoneThoracic RibBone
    CartilageMeckel's CartilageCartilage
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Cartilage-like cells (Differentiation of s...)Cartilage

    See ACPL2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ACPL2

    SOURCE GeneReport for Unigene cluster: Hs.657887
        SABiosciences Custom PCR Arrays for ACPL2
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ACPL2
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACPL2

    Orthologs
    for ACPL2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for ACPL2 gene from 7/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Acpl21 , 5 acid phosphatase-like 21, 5 84.69(n)1
    89.35(a)1    		   9 (50.71 cM)5
    2355341  NM_153420.21  NP_700469.11 
     968233445 
    chicken
    (Gallus gallus)    		 Aves ACPL21 acid phosphatase-like 2 73.12(n)
    75.37(a)    		   424815  XM_422630.3  XP_422630.1 
    lizard
    (Anolis carolinensis)    		 Reptilia ACPL26
    		 --
    		 70(a)
    		 1 ↔ 1
    		 GL343404.1(74856-106111)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia AL967630.12   -- 73.45(n)    AL967630.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii acpl21 acid phosphatase-like 2 59.3(n)
    54.53(a)    		   436703  NM_001002430.1  NP_001002430.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG153851 CG15385 43.82(n)
    29.95(a)    		   33396  NM_134810.3  NP_608654.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea ZK792.11 Protein ZK792.1 40.38(n)
    27.89(a)    		   178100  NM_069806.5  NP_502207.1 


    ENSEMBL Gene Tree for ACPL2 (if available)
    TreeFam Gene Tree for ACPL2 (if available) 

    Paralogs
    for ACPL2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for ACPL2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1276 NCBI SNPs in ACPL2 are shown (see all 1276)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs738695331,2
    		C,--140948787(+) GTCCAC/TGAGTG 2 -- us2k12Minor allele frequency- T:0.04WA 120
    rs1166957541,2
    		F,--140948867(+) AGCCAG/TGTCCA 2 -- us2k11Minor allele frequency- T:0.09WA 118
    rs1474257441,2
    		--140949300(+) GGACAA/GTGAAA 2 -- us2k10--------
    rs1141535711,2
    		F,--140949422(+) TACTGA/GCGAGC 2 -- us2k11Minor allele frequency- G:0.07WA 118
    rs1397913851,2
    		--140949427(+) ACGAGC/TCATTA 2 -- us2k10--------
    rs1453326781,2
    		--140949603(+) ATATCC/TGAGCC 2 -- us2k10--------
    rs1476705371,2
    		--140949754(+) ACACAC/GAGGGT 2 -- us2k10--------
    rs1491531831,2
    		--140949769(+) GTAGAC/GCTCGA 2 -- us2k10--------
    rs558492441,2
    		C,--140950059(+) TGCAGA/GCCGTT 2 -- us2k15Minor allele frequency- G:0.36WA NA EA 362
    rs764839691,2
    		F,--140950072(+) AGACGG/CAGCAG 2 -- us2k11Minor allele frequency- C:0.03WA 118

    HapMap Linkage Disequilibrium report for ACPL2 (140947568 - 141013748 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ACPL2: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ACPL2
    DNA2.0 Custom Variant and Variant Library Synthesis for ACPL2

    Disorders / Diseases
    for ACPL2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ACPL2 for disorders           About GeneDecksing

    1 disease for ACPL2:    About MalaCards
    alcoholism

    Human Genome Epidemiology (HuGE) Navigator: ACPL2 (1 document)

    Export disorders for ACPL2 gene to outside databases

    Publications
    for ACPL2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ACPL2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ACPL2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    2. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    4. Identification of 15 loci influencing height in a Kor ean population. (PubMed id 19893584)1 Kim J.J....Lee J.K. (2010)
    5. A genome-wide study of common SNPs and CNVs in cognit ive performance in the CANTAB. (PubMed id 19734545)1 Need A.C....Goldstein D.B. (2009)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for ACPL2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing ACPL2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 92370 HGNC: 26303 AceView: ACPL2 Ensembl:ENSG00000155893 euGenes: HUgn92370
    ECgene: ACPL2 H-InvDB: ACPL2

    Other Databases showing ACPL2 gene

    (According to HUGE)
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    Specialized Databases showing ACPL2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ACPL2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ACPL2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    		Patent Information for ACPL2 gene:
    Search GeneIP for patents involving ACPL2

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