V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

ACP5 Gene

protein-coding GIFtS: 65

GC19M011546

acid phosphatase 5, tartrate resistant
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EC 3.1.3.2 ^³
MGC117378 ^²
TR-AP ^³
TRAP ^²
TrATPase ^², ³

Descriptions
Tartrate-resistant acid ATPase ^², ³
acid phosphatase 5, tartrate resistant ^², ³
tartrate resistant acid phosphatase 5 ^²

External Ids
HGNC: 124¹
Entrez Gene: 54²
UniProtKB: P13686³
Ensembl: ENSG00000102575⁷

Search outside databases for aliases for ACP5 gene

Previous GC identifers: GC19M011816 GC19M011909 GC19M011530

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ACP5:

This gene encodes an iron containing glycoprotein which catalyzes the conversion of orthophosphoric

monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the

only form not inhibited by L(+)-tartrate. [provided by RefSeq]

Gene Wiki entry for ACP5 (Tartrate-resistant_acid_phosphatase)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ACP5 gene

Entrez Gene cytogenetic band: 19p13.3-p13.2 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19p13.3-p13.2

ACP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M011546: (about GC identifiers)

Start:	11,546,477 bp from pter
End:	11,550,766 bp from pter
Size:	4,290 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000019.8 NT_011295.10

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: PPA5_HUMAN, P13686 (See protein sequence)

Recommended Name: Tartrate-resistant acid phosphatase type 5 precursor

Size: 325 amino acids; 36599 Da

Cofactor: Binds 2 iron ions per subunit

Subunit: Exists either as monomer or, after proteolytic processing, as a dimer of two chains linked

by disulfide bond(s)

Subcellular location: Lysosome

PDB structure from and Proteopedia :

1WAR (3D)

2BQ8 (3D)

Secondary accessions: A8K3V2 Q2TAB1 Q6IAS6 Q9UCJ5 Q9UCJ6 Q9UCJ7

REFSEQ proteins (4 alternative transcripts):

NP_001104504.1 NP_001104505.1 NP_001104506.1 NP_001602.1

ENSEMBL proteins:

ENSP00000218758

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Sigma-Aldrich CompoZr ZFN for ACP5
	R&D Systems Recombinant & Natural Proteins for ACP5 (TRACP/PAP/ACP5)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Tartrate Resistant Acid Phosphatase, Acid phosphatase)
	Human Recombinant Proteins from Abnova (ACP5)

OriGene Purified Recombinant Human Protein: ACP5

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005764	lysosome	IEA	--
GO:0005829	cytosol	EXP	2775236
GO:0016021	integral to membrane	TAS	2338077

About this table

Antibodies for ACP5:

	Invitrogen Antibodies for ACP5
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ACP5
	R&D Systems Antibodies for ACP5 (TRACP/PAP/ACP5)
	Antibodies from Abcam (Tartrate Resistant Acid Phosphatase, Acid phosphatase), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ACP5)
	Novus Biologicals Antibodies for ACP5

Assays for ACP5:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P13686

ProtoNet protein and cluster: P13686

UniProtKB/Swiss-Prot: PPA5_HUMAN, P13686

Similarity: Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ACP5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ACP5)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_001111034

Applied Biosystems Silencer® siRNAs for ACP5

Sigma-Aldrich siRNA and siRNA Panels for ACP5

Sigma-Aldrich shRNA Panels and shRNA for ACP5

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ACP5
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_001111034
Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_001111034
untagged cDNA clones in CMV expression vector (see all 4): NM_001111034

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001611

UniProtKB/Swiss-Prot: PPA5_HUMAN, P13686

Catalytic activity: A phosphate monoester + H(2)O = an alcohol + phosphate

Enzyme Number (IUBMB): EC 3.1.3.2

Genatlas biochemistry entry for ACP5:

phosphatase acid,tartrate resistant

3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Acp5):

immune system

limbs/digits/tail

skeleton

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003993	acid phosphatase activity	TAS	8359686
GO:0005506	iron ion binding	IEA	--
GO:0016787	hydrolase activity	IEA	--
GO:0046872	metal ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for ACP5 (Your Favorite Gene powered by Ingenuity)

Riboflavin Metabolism

GeneDecks ACP5 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for ACP5

5/26 Interacting proteins for ACP5 (ENSP00000218758³ P13686²) via UniProtKB, MINT, and/or STRING (see all 26 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
EGR2	P11161²	MINT-63454
MAPK9	P45984²	MINT-64907
PDCD5	O14737²	MINT-63066
SNRNP40	Q96DI7²	MINT-65122
TNFSF10	P50591²	MINT-63835

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0034097	response to cytokine stimulus	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ACP5
10/25 Novoseek chemical compound relationships for ACP5 gene (see all 25 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
deoxypyridinoline	71.28	23	8911707 (3), 8352070 (3), 18256306 (2), 9580479 (1) (see all 11)
pyridinoline	66.66	19	8352070 (3), 7785468 (2), 9580479 (1), 12525759 (1) (see all 8)
hydroxyproline	58.04	23	7561234 (2), 8304043 (2), 7785468 (2), 7799895 (2) (see all 14)
1,25 dihydroxy vitamin d3	49.37	1	2323362 (1)
procollagen	49.01	5	10354264 (1), 15252851 (1), 8879839 (1)
hydroxyapatite	35.81	4	11336305 (2), 9878526 (1)
toluidine	32.36	3	15293474 (1), 18773818 (1)
molybdate	28.43	2	8889844 (1), 8127141 (1)
calcium	24.34	32	7516333 (5), 7561234 (2), 9333133 (2), 14606707 (2) (see all 15)
nitroblue tetrazolium	17.56	2	1693566 (2)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ACP5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ACP5)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_001111034

Sigma-Aldrich siRNA and siRNA Panels for ACP5

Sigma-Aldrich shRNA Panels and shRNA for ACP5

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001111034 NM_001111035 NM_001111036 NM_001611

REFSEQ mRNAs for ACP5 gene (4 alternative transcripts):

NM_001111034.1 NM_001111035.1 NM_001111036.1 NM_001611.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001111034 NM_001111035 NM_001111036 NM_001611

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_001111034
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_001111034
                                 untagged cDNA clones in CMV expression vector (see all 4): NM_001111034

Additional cDNA sequence:

AK225912.1 AK290717.1 AK307164.1 BC025414.2 BC111014.1 CR457078.1 CR602962.1 CR615022.1

CR616016.1 CR617566.1 CR618497.1 CR624625.1 J04430.1 X14618.1

20 DOTS entries:

DT.100709596 DT.100813137 DT.453685 DT.95152222 DT.100813140 DT.100029488 DT.121462889 DT.100813139

DT.95196730 DT.100834376 DT.121462939 DT.121462950 DT.91731286 DT.121462876 DT.121463016 DT.121463190

DT.121629898 DT.40248088 DT.91731291 DT.95088531

24/214 AceView cDNA sequences (see all 214 ):

CB529122 BU732014 BM686163 BU632205 CD370690 CD367224 CD370009 BQ683467

CA436118 CA308313 BI820158 BX378750 CA430104 BG761938 BX399056 NM_001611

BC025414 BQ445828 BU189620 CR602962 BM662527 AV646064 CA435155 BM992573

highest scoring ESTs for ACP5:

J04430 BC025414 BE277003 BF974850 BG547651 BG760210 BG761938 BG762357 BG766939 BG769534

Unigene Cluster for ACP5:

Acid phosphatase 5, tartrate resistant

Hs.1211 [show with all ESTs]

Unigene Representative Sequence: BM804974

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ACP5 (see all 8 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	·	2c	^	3a	·	3b	^	4a	·	4b	·	4c	^	5a	·	5b	·	5c	·	5d	^	6a	·	6b	·	6c	·	6d	^	7
SP1:									-		-		-		-				-
SP2:									-				-		-				-
SP3:													-		-				-
SP4:									-		-		-		-				-
SP5:									-						-				-

About this scheme

ECgene alternative splicing isoforms for ACP5

1 Ensembl transcript including schematic representation:

ENST00000218758

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ACP5 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ACP5

¹ / ² / ³

3 probe-sets matching ACP5 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
677_s_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	J04430	1.00	1.00	1.00	1
204638_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001611	0.60	1.00	0.82	1
204638_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks ACP5 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGTCCCAGCC

SOURCE GeneReport for Unigene cluster: Hs.1211
Expression variation in blood from EXPOLDB for ACP5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ACP5 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ACP5¹	--	acid phosphatase 5, tartrate resistant	85.91(n) 90.12(a)	476705 XM_533910.2 XP_533910.2
cow (Bos taurus)	ACP5¹	--	acid phosphatase 5, tartrate resistant	84.16(n) 86.42(a)	517002 XM_595165.3 XP_595165.2
mouse (Mus musculus)	Acp5^{1, 5}	9 (6.00 cM)⁵	acid phosphatase 5, tartrate resistant^{1, 5}	81.44(n)¹ 85.54(a)¹	11433¹ NM_007388.2¹ NP_031414.1¹ AK008391⁵ AK010865⁵ (see all 20)
zebrafish (Danio rerio)	wufb30b03²	--	Danio rerio cDNA clone MGC63825 IMAGE3816467, complete more	72.01(n)	BC055256.1
worm (Caenorhabditis elegans)	F02E9.7^{1, 3}	I(8421352-8424146)³	acid phosphatase³ hypothetical protein¹	36(a)³ 46.08(n)¹ 40.96(a)¹	172627¹ NM_059882.3¹ NP_492283.1¹

About this table Species with no ortholog for ACP5

ENSEMBL Gene Tree for ACP5

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/27 NCBI SNPs in ACP5 are shown (see all 27 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 22)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs2071484^1,2	A,C,F,H	11549460(-)	`ACTCTA/GGAGCC`	4	--	ut5¹ ese³		11		EA NA MN EU WA	2474
	rs3760780^1,2	A,C,F,H	11550158(-)	`GTGGGA/GTGGAG`	1	--	ng3¹		5		EA EU WA	1896
	rs2305799^1,2	C,F,H	11548351(+)	`AGACAC/TATTGG`	4	V/M	mis¹ ese³		10		EA EU WA NA	2404
	rs2229532^1,2	C,F,H	11548132(-)	`GCCTGG/ATCAAG`	4	I/V	mis¹ ese³		13		MN NA EU EA WA	1078
	rs2229531^1,2	C,F,H	11548195(-)	`ACTACG/ATGCTG`	4	M/V	mis¹ ese³		11		MN EA EU WA NA	2434
	rs2071483^1,2	C,F	11549539(-)	`GCCCTC/AGGAGA`	1	--	ut5¹		3		EA MN	1846
--	rs7256770^1,2	A,C	11550911(+)	`CCCAAA/GGGTCG`	1	--	ng3¹		0	--	--	--	--
--	rs10425533^1,2	A,C	11546170(+)	`ctcccA/Gagtag`	1	--	ng5¹		0	--	--	--	--
--	rs17001464^1,2	F	11549960(-)	`GACAAG/-CCACA`	1	--	ng3¹		2		MN EA	356
	rs2071485^1,2	C,F	11549200(-)	`GCAGGC/TGGGGG`	1	--	int¹		5		EA NA	1844

About this table

HapMap Linkage Disequilibrium images for ACP5 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 171640

UniProtKB/Swiss-Prot: PPA5_HUMAN, P13686

This relatively minor intracellular isozyme of acid phosphatase can become the dominant

isozyme in certain pathological states (Gaucher and Hodgkin diseases, the hairy cell, the B-cell,

and the T-cell leukemias)

10/41 Novoseek disease relationships for ACP5 gene (see all 41 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
osteoclastoma	85.66	6	7768539 (1), 10784406 (1), 8463220 (1), 11838317 (1) (see all 5)
leukemia hairy cell	79.56	14	9888357 (1), 15222122 (1), 9145320 (1), 9291460 (1) (see all 14)
bone destruction	65.37	1	9145320 (1)
bone diseases	62.75	5	16869970 (2), 2402608 (1), 17088078 (1)
bone loss	62.68	1	17963952 (1)
osteolysis	58.97	2	9730060 (1), 15513686 (1)
gaucher disease	54.34	6	9291460 (1), 10784406 (1), 11373314 (1), 8618440 (1) (see all 6)
bone diseases metabolic	51.64	2	1750188 (1), 1767245 (1)
rheumatoid arthritis	46.09	4	19333923 (1), 11020469 (1), 12594102 (1)
hyperparathyroidism secondary	45.34	3	12589973 (2), 1750188 (1)

About this table

Human Genome Epidemiology Navigator: ACP5 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/296 PubMed articles for ACP5 gene (see all 296 ):

Type 5 acid phosphatase. Sequence, expression and chromosomal localization of a differentiation-associated protein of the human macrophage. (PubMed id 2338077)^{2, 3, 4} Lord D.K....Cox T.M. (1990)
Assignment of the mouse tartrate-resistant acid phosphatase gene (Acp5) to chromosome 9. (PubMed id 8449511)^{1, 2, 3} Grimes R....Windle J.J. (1993)
Purification and N-terminal amino acid sequence of the tartrate- resistant acid phosphatase from human osteoclastoma: evidence for a single structure. (PubMed id 2334436)^{1, 3, 4} Stepan J.J.... Baylink D.J. (1990)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Isolation and characterization of the genes encoding mouse and human type-5 acid phosphatase. (PubMed id 8359686)^{3, 4} Cassady A.I.... Hume D.A. (1993)
Tartrate-resistant acid phosphatase from human osteoclastomas is translated as a single polypeptide. (PubMed id 1872798)^{3, 4} Hayman A.R.... Warburton M.J. (1991)
Purification and N-terminal sequence of two tartrate-resistant acid phosphatases type-5 from the hairy cell leukemia spleen. (PubMed id 2610679)^{3, 4} Stepan J.J.... Baylink D.J. (1989)
Molecular cloning of the type 5, iron-containing, tartrate-resistant acid phosphatase from human placenta. (PubMed id 2909539)^{3, 4} Ketcham C.M.... Nick H.S. (1989)
Purification and characterization of a tartrate-resistant acid phosphatase from human osteoclastomas. (PubMed id 2775236)^{3, 4} Hayman A.R.... Chambers T.J. (1989)
Increased tartrate-resistant acid phosphatase (TRAP) expression in malignant breast, ovarian and melanoma tissue: an investigational study. (PubMed id 16869970)^{1, 3} Honig A....Kammerer U. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 54	HGNC: 124	AceView: ACP5	Ensembl:ENSG00000102575	euGenes: HUgn54
ECgene: ACP5	H-InvDB: ACP5

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for ACP5	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for ACP5
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ACP5:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ACP5-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ACP5		Antibodies for ACP5
	Explore super-pooled esiRNAs		Proteins for ACP5
	Lentivirus-delivered shRNAs for ACP5		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (ACP5)
	Antibodies (ACP5)
	Chimera RNAi (ACP5)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Tartrate Resistant Acid Phosphatase, Acid phosphatase)
	Antibodies (Tartrate Resistant Acid Phosphatase, Acid phosphatase)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for ACP5

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ACP5

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
ACP5 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

ACP5 Gene

protein-coding GIFtS: 65

Aliases &
Descriptions
for ACP5

Summaries
for ACP5

Genomic Location
for ACP5

Proteins
for ACP5

Protein Domains/
Families
for ACP5

Gene Function
for ACP5

Pathways & Interactions
for ACP5

Drugs & Compounds
for ACP5

Transcripts
for ACP5

Expression
for ACP5

Orthologs
for ACP5

Paralogs
for ACP5

SNPs/Variants
for ACP5

Disorders & Mutations
for ACP5

Medical News
for ACP5

Publications
for ACP5

Search for ACP5

Genome Databases showing ACP5

Other Databases showing ACP5

Specialized Databases showing ACP5

Licensable Technologies
for ACP5

Services
for ACP5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ACP5 Gene

protein-coding GIFtS: 65

Aliases & Descriptionsfor ACP5

Summariesfor ACP5

Genomic Locationfor ACP5

Proteinsfor ACP5

Protein Domains/Familiesfor ACP5

Gene Functionfor ACP5

Pathways & Interactionsfor ACP5

Drugs & Compoundsfor ACP5

Transcriptsfor ACP5

Expression for ACP5

Orthologsfor ACP5

Paralogsfor ACP5

SNPs/Variantsfor ACP5

Disorders & Mutationsfor ACP5

Medical Newsfor ACP5

Publicationsfor ACP5

Search for ACP5

Genome Databases showing ACP5

Other Databases showing ACP5

Specialized Databases showing ACP5

Licensable Technologiesfor ACP5

Servicesfor ACP5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ACP5

Summaries
for ACP5

Genomic Location
for ACP5

Proteins
for ACP5

Protein Domains/
Families
for ACP5

Gene Function
for ACP5

Pathways & Interactions
for ACP5

Drugs & Compounds
for ACP5

Transcripts
for ACP5

Expression
for ACP5

Orthologs
for ACP5

Paralogs
for ACP5

SNPs/Variants
for ACP5

Disorders & Mutations
for ACP5

Medical News
for ACP5

Publications
for ACP5

Licensable Technologies
for ACP5

Services
for ACP5