ACP1 Gene
protein-coding GIFtS : 69
GCID: GC02 P000254
acid phosphatase 1, soluble
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Aliasesfor ACP1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section This gene clusters with an RNA geneSubcategory (RNA class): lncRNAQuality score for the ORGUL clustered with this gene is 3 Aliases Acid Phosphatase 1, Soluble 1 2 Acid Phosphatase Of Erythrocyte2 Adipocyte Acid Phosphatase2 3 Cytoplasmic Phosphotyrosyl Protein Phosphatase2 Low Molecular Weight Cytosolic Acid Phosphatase2 3 Low Molecular Weight Phosphotyrosine Protein Phosphatase2 Red Cell Acid Phosphatase 12 3 Protein Tyrosine Phosphatase2 LMW-PTP2 3 EC 3.1.3.23 LMW-PTPase2 3 EC 3.1.3.483 HAAP2
External Ids: HGNC: 122 1 Entrez Gene: 52 2 Ensembl: ENSG00000143727 7 OMIM: 171500 5 UniProtKB: P24666 3 ORGUL members: NONCODE:n406571
Export aliases for ACP1 gene to outside databases Previous GC identifer: GC02P000258
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Summariesfor ACP1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for ACP1 : The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. (provided by RefSeq, Aug 2008) UniProtKB/Swiss-Prot: PPAC_HUMAN, P24666 Function : Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.Isoform 3 does not possess phosphatase activity Gene Wiki entry for ACP1
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Genomic Viewsfor ACP1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000002.11 NC_018913.1 NT_022221.13 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ACP1 gene promoter: STAT5B p53 Pax-2 STAT3 Pax-2a Meis-1 GATA-2 Other transcription factors Search SABiosciences Chromatin IP Primers for ACP1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat ACP1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 2p25 Ensembl cytogenetic band: 2p25.3 HGNC cytogenetic band: 2p25 ACP1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 2 GeneLoc Exon Structure
GeneLoc location for GC02P000254: view genomic region
(about GC identifiers )
Start:
264,140 bp from pter
End:
278,283 bp from pter
Size:
14,144 bases
Orientation:
plus strand
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Proteinsfor ACP1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: PPAC_HUMAN, P24666 (See
protein sequence )Recommended Name: Low molecular weight phosphotyrosine protein phosphatase Size : 158 amino acids; 18042 Da
Subunit : Isoform 1 interacts with the SH3 domain of SPTAN1. There is no interaction observed for isoforms 2 or 3.Interacts with EPHA2; dephosphorylates EPHA2. Interacts with EPHB1
Subcellular location : Cytoplasm
3 PDB 3D structures from and Proteopedia for ACP1 :1XWW (3D)
  3N8I (3D)
  5PNT (3D)
 
Secondary accessions : A8K1L9 P24667 Q16035 Q16036 Q16725 Q3KQX8 Q53RU0Alternative splicing : 3 isoforms : P24666-1 P24666-2, P24667-1 P24666-3 Explore the universe of human proteins at neXtProt for ACP1: NX_P24666 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_P24666 ACP1 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (3 alternative transcripts):
NP_001035739.1 NP_004291.1 NP_009030.1 ENSEMBL proteins: ENSP00000272067 ENSP00000272065 ENSP00000410331 ENSP00000385404 ENSP00000389681 ENSP00000408596 ENSP00000384184 ENSP00000384307 ENSP00000411121 Human Recombinant Protein Products: Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6 ): About this table
ACP1 for ontologies About GeneDecksing ACP1 Antibody Products: Assay Products for ACP1:
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Protein
Domains / Familiesfor ACP1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
ACP1 for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry P24666 ProtoNet protein and cluster: P24666
2 Blocks protein families : IPB000106 LMW phosphotyrosine protein phosphatase signature IPB002115 Mammalian LMW phosphotyrosine protein phosphatase signature UniProtKB/Swiss-Prot: PPAC_HUMAN, P24666 Similarity : Belongs to the low molecular weight phosphotyrosine protein phosphatase family
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Functionfor ACP1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: PPAC_HUMAN, P24666 Function : Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.Isoform 3 does not possess phosphatase activity Catalytic activity : Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphateCatalytic activity : A phosphate monoester + H(2)O = an alcohol + phosphateEnzyme regulation : Inhibited by sulfhydryl reagents
Genatlas biochemistry entry for ACP1 : phosphatase acid,red cell Enzyme Numbers (IUBMB): EC 3.1.3.48 1 EC 3.1.3.2 1 Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ACP1 (see all 7 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ACP1 (see all 6 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): ACP1 (NM_001040649 ) Sino Biological Human cDNA Clone for ACP1 DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACP1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ACP1
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACP1
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6 ): About this table
ACP1 for ontologies About GeneDecksing Animal Models: Mouse knock-out Acp1 tm1Lex for ACP1 3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Acp1) :
ACP1 for phenotypes About GeneDecksing
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Pathways & Interactionsfor ACP1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways   About this table See pathways by source Super-pathway contained gene-specific pathways 1 EPHA2 forward signaling 2 Adherens junction 3 Riboflavin metabolism 4 PDGFR-beta signaling pathway
Pathway sources See GeneCards unified pathways Show all pathways 2 BioSystems Pathways for ACP1 2
Kegg Pathways (Kegg details for ACP1) :
ACP1 for pathways About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ACP1 STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/53 Interacting proteins for ACP1 (P24666 1 , 3 ENSP00000272065 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 53 )About this table Gene Ontology (GO): 3 biological process terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0007268 synaptic transmission
IEA -- GO:0016311 dephosphorylation
-- -- GO:0035335 peptidyl-tyrosine dephosphorylation
-- --
ACP1 for ontologies About GeneDecksing
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Drugs & Compoundsfor ACP1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section
ACP1 for compounds About GeneDecksing Browse Tocris compounds for ACP1 6 HMDB Compounds for ACP1 About this table 2 DrugBank Compounds for ACP1 About this table 10/116 Novoseek chemical compound relationships for ACP1 gene (see all 116 ) About this table
Compound
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
tyrosine
94.6
3576
16039061 (12), 15477998 (6), 10980198 (5), 8258363 (5) (see all 99 )
phosphotyrosine
91.9
211
7679612 (5), 2134890 (3), 8620937 (3), 7686722 (3) (see all 99 )
sodium orthovanadate
88.7
78
10230815 (2), 11507066 (2), 8186375 (1), 8014198 (1) (see all 66 )
vanadate
88.1
139
11980490 (4), 2154464 (3), 9878539 (2), 10439081 (2) (see all 99 )
phenylarsine oxide
82.6
54
8581996 (2), 7738000 (2), 1423640 (2), 9341756 (2) (see all 31 )
raytide
80.3
5
1318316 (1), 7684610 (1), 8256510 (1)
p-nitrophenyl phosphate
76.9
8
8127855 (2), 2134890 (1), 19414171 (1), 7528537 (1) (see all 7 )
dephostatin
75.7
9
8557604 (4), 8226312 (1), 20130847 (1)
bpv(phen)
71.2
3
16039061 (1), 11792460 (1)
benzylphosphonic acid
70
2
9458714 (1), 9106619 (1)
Search CenterWatch for drugs/clinical trials and news about ACP1 / PPAC
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Transcriptsfor ACP1 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for ACP1 gene (4 alternative transcripts): NM_001040649.2 NM_004300.3 NM_007099.3 NM_177554.1 Unigene Cluster for ACP1:
Acid phosphatase 1, soluble Hs.558296 [show with all ESTs ] Unigene Representative Sequence: NR_024080 13 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000484125 ENST00000272067 (uc002qwg.3 uc002qwh.3 ) ENST00000272065 (uc002qwf.3 )ENST00000413140 ENST00000407983 (uc002qwd.2 ) ENST00000442386 ENST00000439645 ENST00000405364 ENST00000405233 (uc002qwe.4 ) ENST00000480874 ENST00000453390 ENST00000484464 ENST00000463831 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ACP1 (see all 7 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ACP1 (see all 6 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): ACP1 (NM_001040649 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACP1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ACP1
Additional cDNA sequence: AB209838.1 AK289934.1 AK291861.1 BC007422.2 BC106011.1 BT007136.1 M83653.1 M83654.1 M87545.1 NR_024080.1 S62884.1 Y16846.1
20 DOTS entries : DT.100842980 DT.99931855
DT.100030203 DT.454219 DT.100842972 DT.100842978 DT.100742580 DT.121013711 DT.119141 DT.95256266 DT.100842976 DT.100842982 DT.119140 DT.95256302 DT.121013776 DT.121013819 DT.91759792 DT.95256278 DT.121417499 DT.99984839 24/473 AceView cDNA sequences (see all 473 ):
BM477153 CR609595 CB162252 AL552042 BP872697 BM667352 BQ226796 AI141163 CR607431 BM716010 BM770461 AI168086 BG056276 BE905801 AL573837 AI167367 N90219 BM825165 BM793724 AI056981 BE618323 AW951882 AI870895 R29518 GeneLoc Exon Structure 5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ACP1 (see all 9 ) About this scheme ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d · 9e · 9f · 9g SP1 :           -       -       -   -   -                     SP2 :           -   -     -     -   -     -                     SP3 :           -   -     -   -   -   -     -                     SP4 :           -   -     -       -   -   -                     SP5 :             -     -       -   -   -                    
ECgene alternative splicing isoforms for ACP1
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Expression for ACP1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ACP1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AATATTTCAA
About this image ACP1 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See ACP1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ACP1 SOURCE GeneReport for Unigene cluster: Hs.558296 UniProtKB/Swiss-Prot: PPAC_HUMAN, P24666 Tissue specificity : T-lymphocytes express only isoform 2 SABiosciences Expression via Pathway-Focused PCR Array including ACP1 : Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for ACP1Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat ACP1 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ACP1 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ACP1 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACP1
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Orthologsfor ACP1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the last universal common ancestor (LUCA).
Orthologs for ACP1 gene from 10/31 species (see all 31 ) About this table
ENSEMBL Gene Tree for ACP1 (if available)TreeFam Gene Tree for ACP1 (if available)
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Paralogsfor ACP1 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for ACP1 gene
ACP1 for paralogs About GeneDecksing 5/6 Pseudogenes.org Pseudogenes for ACP1 (see all 6 )PGOHUM00000238865 PGOHUM00000248729 PGOHUM00000248738 PGOHUM00000249002 PGOHUM00000244482
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Genomic Variantsfor ACP1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section UniProtKB/Swiss-Prot: PPAC_HUMAN, P24666 Polymorphism : ACP1 is genetically polymorphic. Three common alleles are known in Caucasians: ACP1*A, ACP1*B and ACP1*C.They give rise to six different phenotypes. Each allele appears to encode two electrophoretically different isozymes, F and S, which are produced in allele-specific ratios. The sequence shown is that of allele ACP1*B and allele ACP1*C
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 2 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for ACP1 (264140 - 278283 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for ACP1 2 CNVs : 2360 3341
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ACP1
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Disorders
/ Diseasesfor ACP1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
ACP1 for disorders About GeneDecksing
OMIM gene information: 171500
OMIM disorders : --20/132 diseases for ACP1 (see all 132 ): About MalaCards bubonic plague multiple symmetrical lipomatosis multiple symmetric lipomatosis diffuse large b-cell lymphoma guillain-barre syndrome familial adenomatous polyposis alcoholism polycythemia vera centronuclear myopathy adenomatous polyposis coli favism myoclonus epilepsy b-cell lymphomas progressive myoclonus epilepsy leopard syndrome plague lafora disease okamoto syndrome type 2 diabetes mellitus diabetes mellitus 3 diseases from the University of Copenhagen DISEASES database for ACP1 :Favism Arthropathy Multiple symmetric lipomatosis 10/90 Novoseek disease relationships for ACP1 gene (see all 90 ) About this table
Disease
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
noonan syndrome
70
11
15240615 (2), 12161469 (2), 16208280 (1), 19541608 (1) (see all 9 )
bubonic plague
60.8
7
1723471 (1), 14609321 (1), 8052312 (1), 7803389 (1) (see all 5 )
centronuclear myopathy
49.8
2
10900271 (1), 11056007 (1)
lafora disease
45
6
9771710 (1), 16134145 (1), 14643920 (1), 17010495 (1) (see all 5 )
insulin resistance
40.4
32
18925540 (4), 15271787 (2), 7769120 (2), 7535776 (1) (see all 21 )
autoimmunity
36.4
6
17608818 (1), 11826758 (1), 18303998 (1), 18416318 (1) (see all 6 )
leopard syndrome
36.1
1
16208280 (1)
favism
34.7
2
8522318 (1), 9116311 (1)
diabetes autoimmune
32.7
2
18056891 (1)
immune disorder
32.6
2
18490013 (1), 19246900 (1)
Genetic Association Database (GAD): ACP1 Human Genome Epidemiology (HuGE) Navigator: ACP1 (44 documents) Export disorders for ACP1 gene to outside databases
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Publicationsfor ACP1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ACP1 gene, integrated from 9 sources (see all 1493 ): (articles sorted by number of sources associating them with ACP1) Utopia : connect your pdf to the dynamic world of online information
Association of the ACP1 genotype with metabolic parameters upon initial diagnosis of type 1 diabetes. (PubMed id 12640337) 1 , 4, 9 Meloni G....Bottini E. (2003) Type 2 diabetes and the genetics of signal transduction: a study of interaction between adenosine deaminase and acid phosphatase locus 1 polymorphisms. (PubMed id 15281007) 1 , 4, 9 Bottini N....Bottini E. (2004) Association of the acid phosphatase (ACP1) gene with triglyceride levels in obese women. (PubMed id 12409270) 1 , 4, 9 Bottini N....Comings D.E. (2002) Genetic polymorphism and TH1/TH2 orientation. (PubMed id 16224193) 1 , 4, 9 Bottini N....Bottini E. (2005) [Genetic predisposition to development of toxic liver cirrhosis caused by alcohol] (PubMed id 11436564) 1 , 4, 9 Spitsyn V.A....Afanas'eva I.S. (2001) Risk of type 1 diabetes in childhood and maternal age at delivery, interaction with ACP1 and sex. (PubMed id 15586390) 1 , 4, 9 Bottini N....Bottini E. (2005) Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation. (PubMed id 12167657) 1 , 2 , 9 Kikawa K.D....Kinch M.S. (2002) [Genetic polymorphism of erythrocytic enzymes in Yakut populations] (PubMed id 11963573) 1 , 4, 9 Tarskaia L.A....Spitsin V.A. (2002) The genetics of signal transduction and the effect of smoking on intrauterine growth. (PubMed id 11369750) 1 , 4, 9 Bottini E....Lucarini N. (2001) Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. Implications for substrate specificity. (PubMed id 9705307) 1 , 2 , 9 Zhang M.... van Etten R.L. (1998)
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External Searches for ACP1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ACP1 gene
(According to
Entrez Gene ,
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euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
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Other Databases showing ACP1 gene
(According to HUGE )
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Specialized Databases showing ACP1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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About This Section Patent Information for ACP1 gene: Search GeneIP for patents involving ACP1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ACP1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for ACP1 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for ACP1 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for ACP1 OriGene Protein Over-expression Lysate for ACP1 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for ACP1 OriGene 3'-UTR Clone for ACP1 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ACP1 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ACP1 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for ACP1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for ACP1 OriGene Custom Protein Services for ACP1 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ACP1 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ACP1 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat ACP1 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat ACP1 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ACP1 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ACP1
Search Tocris compounds for ACP1
Recombinant Protein for ACP1
ACP1 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACP1
ThermoFisher Antibody for ACP1
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ACP1
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