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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ACOX3 Gene

protein-coding   GIFtS: 64
GCID: GC04M008368

acyl-CoA oxidase 3, pristanoyl

(Previous names: acyl-Coenzyme A oxidase 3, pristanoyl )
 Explore 6 diseases affiliated with
ACOX3 via our new
 Human Malady Compendium 
Biological research products
for ACOX3
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Acyl-CoA Oxidase 3, Pristanoyl1 2     Peroxisomal Acyl-Coenzyme A Oxidase 32
Acyl-Coenzyme A Oxidase 3, Pristanoyl1 2     BRCOX3
Branched-Chain Acyl-CoA Oxidase2 3     EC 1.3.3.63
Pristanoyl-CoA Oxidase2 3     PRCOX3
BRCACox2 3     

External Ids:    HGNC: 1211   Entrez Gene: 83102   Ensembl: ENSG000000870087   OMIM: 6034025   UniProtKB: O152543   

Export aliases for ACOX3 gene to outside databases

Previous GC identifers: GC04M008343 GC04M008549 GC04M008561 GC04M008486 GC04M008287


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ACOX3:
Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl
branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver
such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme
activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting
C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific
developmental stages or in a tissue specific manner in tissues that have not yet been examined. (provided by RefSeq,
Jul 2008)

UniProtKB/Swiss-Prot: ACOX3_HUMAN, O15254
Function: Oxidizes the CoA-esters of 2-methyl-branched fatty acids (By similarity)

Gene Wiki entry for ACOX3


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_006051.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ACOX3 gene promoter:
         TBP   RFX1   Pax-2   Pax-2a   XBP-1   HNF-3beta   CREB   TFIID   deltaCREB   COMP1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): ACOX3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ACOX3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACOX3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p15.3   Ensembl cytogenetic band:  4p16.1   HGNC cytogenetic band: 4p15.3

ACOX3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACOX3 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M008368:  view genomic region     (about GC identifiers)

Start:
8,368,009 bp from pter      End:
8,442,452 bp from pter
Size:
74,444 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ACOX3_HUMAN, O15254 (See protein sequence)
Recommended Name: Peroxisomal acyl-coenzyme A oxidase 3  
Size: 700 amino acids; 77629 Da
Cofactor: FAD (By similarity)
Subcellular location: Peroxisome (Potential)
Secondary accessions: Q96AJ8
Alternative splicing: 2 isoforms:  O15254-1   O15254-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ACOX3: NX_O15254

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O15254

  • ACOX3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001095137.1  NP_003492.2  

    ENSEMBL proteins: 
     ENSP00000413994   ENSP00000348775   ENSP00000421625   ENSP00000427321  
    Reactome Protein details: O15254
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    Uscn Proteins for ACOX3

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0005777peroxisome IDA8993592
    GO:0005782peroxisomal matrix TAS--


    ACOX3 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ACOX3 for domains           About GeneDecksing

    5/6 InterPro domains/families (see all 6):
     IPR006090 Acyl-CoA_Oxase/DH_1
     IPR012258 Acyl-CoA_oxidase
     IPR009100 AcylCoA_DH/oxidase
     IPR006091 Acyl-CoA_Oxase/DH_cen-dom
     IPR002655 Acyl-CoA_oxidase_C

    Graphical View of Domain Structure for InterPro Entry O15254

    ProtoNet protein and cluster: O15254

    1 Blocks protein family: IPB002655 Acyl-CoA oxidase

    UniProtKB/Swiss-Prot: ACOX3_HUMAN, O15254
    Similarity: Belongs to the acyl-CoA oxidase family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ACOX3_HUMAN, O15254
    Function: Oxidizes the CoA-esters of 2-methyl-branched fatty acids (By similarity)
    Catalytic activity: Acyl-CoA + O(2) = trans-2,3-dehydroacyl-CoA + H(2)O(2)

         Genatlas biochemistry entry for ACOX3:
    branched-chain acyl-CoA oxidase 3,peroxisomal,acting on the CoA-esters of pristanic acid and straight chain mono-and
    dicarboxy fatty acids,expression below detection limit in man,extremely weakly expressed in liver,may be expressed
    under special conditions and tissues so far not examined

    Enzyme Number (IUBMB): EC 1.3.3.61

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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003995acyl-CoA dehydrogenase activity IEA--
    GO:0003997acyl-CoA oxidase activity ----
    GO:0005102receptor binding IPI--
    GO:0016402pristanoyl-CoA oxidase activity TAS--
    GO:0050660flavin adenine dinucleotide binding IEA--


    ACOX3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for ACOX3:
     Decreased melanin production 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Metabolism
    Metabolism1.00
    Metabolism of lipids and lipoproteins0.34
    Metabolic pathways0.38
    2Peroxisomal lipid metabolism
    Peroxisomal lipid metabolism1.00
    Beta-oxidation of pristanoyl-CoA0.40
    3Peroxisome
    Peroxisome1.00
    4PPAR signaling pathway
    PPAR signaling pathway1.00
    5Biosynthesis of unsaturated fatty acids
    Biosynthesis of unsaturated fatty acids1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4        Reactome Pathways for ACOX3
        Beta-oxidation of pristanoyl-CoA
    Metabolism
    Peroxisomal lipid metabolism
    Metabolism of lipids and lipoproteins


    5/6         Kegg Pathways  (Kegg details for ACOX3) (see all 6):
        Fatty acid metabolism
    alpha-Linolenic acid metabolism
    Biosynthesis of unsaturated fatty acids
    Metabolic pathways
    PPAR signaling pathway

    UniProtKB/Swiss-Prot: ACOX3_HUMAN, O15254
    Pathway: Lipid metabolism; peroxisomal fatty acid beta-oxidation


    ACOX3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ACOX3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    5/25 Interacting proteins for ACOX3 (O152542, 3 ENSP000003487754) via UniProtKB, MINT, STRING, and/or I2D (see all 25)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMURF2Q9HAU42, 3MINT-61801 I2D: score=3 
    SLC2A4P146723I2D: score=1 
    ACAA1ENSP000003336644STRING: ENSP00000333664
    ACAA2ENSP000002850934STRING: ENSP00000285093
    ACAT1ENSP000002658384STRING: ENSP00000265838
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006631fatty acid metabolic process ----
    GO:0033540fatty acid beta-oxidation using acyl-CoA oxidase TAS--
    GO:0044255cellular lipid metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--


    ACOX3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ACOX3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ACOX3

    10/42 HMDB Compounds for ACOX3 (see all 42)    About this table
    CompoundSynonyms CAS #PubMed Ids
    (2E)-Decenoyl-CoA(E)-S-2-decenoate Coenzyme A (see all 15)10018-95-8--
    (2E)-Dodecenoyl-CoA2-trans-Dodecenoyl-Coenzyme A (see all 4)1066-12-2--
    (2E)-Hexadecenoyl-CoAtrans-2-Hexadecenoyl-CoA (see all 4)4460-95-1--
    (2E)-Octenoyl-CoA(E)-S-2-octenoate Coenzyme A (see all 16)10018-94-7--
    (2E)-Tetradecenoyl-CoA(2E)-Tetradecenoyl-Coenzyme A (see all 8)38795-33-4--
    (2S,6R,10R)-Trimethyl-hendecanoyl-CoA((2S),(6R),10)-trimethylundecanoyl-CoA (see all 8)----
    2-Methylbutyryl-CoA2-methylbutanoyl-CoA (see all 11)6712-02-3--
    2-Methylhexanoyl-CoA2-Methylhexanoyl-CoEnzyme A (see all 5)----
    20-CoA-20-oxo-leukotriene B4CoA-20-COOH-LTB(,4) (see all 2)----
    3Z-dodecenoyl-CoAS-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-dodec-3-enethioate (see all 4)2152-91-2--
    6 Novoseek chemical compound relationships for ACOX3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    pristanic acid 95.5 3 10709653 (1), 8387517 (1), 9803880 (1)
    acyl-coa 83.8 6 9053547 (1), 8556358 (1), 9803880 (1)
    phytanic acid 83.2 1 1770789 (1)
    tripeptide 54.1 1 8706733 (1)
    sterol 42.5 3 11330072 (1), 9803880 (1)
    fatty acid 27.5 2 15599942 (1)

    Search CenterWatch for drugs/clinical trials and news about ACOX3 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ACOX3 gene (2 alternative transcripts): 
    NM_001101667.1  NM_003501.2  

    Unigene Cluster for ACOX3:

    Acyl-CoA oxidase 3, pristanoyl
    Hs.479122  [show with all ESTs]
    Unigene Representative Sequence: BX640768
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000512411 ENST00000515797 ENST00000413009(uc003gld.4) ENST00000356406(uc010idk.3 uc003glc.4)
    ENST00000503233 ENST00000510365 ENST00000508302 ENST00000514423

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    Additional cDNA sequence: 

    AK225080.1 AK313242.1 BC017053.1 BX640768.1 Y11411.1 

    10 DOTS entries:

    DT.100742019  DT.315013  DT.95141073  DT.97841659  DT.101966593  DT.95261316  DT.75102844  DT.86848005 
    DT.91740564  DT.95155153 

    24/141 AceView cDNA sequences (see all 141):

    CF132142 CA438485 BM837705 BU728389 AI436007 BM010643 BM773520 BX364074 
    Z40378 BU857907 BF724168 AI571140 BM682926 Z45527 AU132016 AU141142 
    AU131606 CR609446 BQ436455 AI435950 R32150 BF055976 CA306669 F09801 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ACOX3 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19a · 19b ^ 20 ^ 21a ·
    SP1:                                                                                                              -                 -     -                     
    SP2:              -     -     -                                                                                   -                 -     -     -               
    SP3:                                                                                                                                                            
    SP4:                                -                                                                                                                           
    SP5:                                                                                                                                -     -                     

    ExUns: 21b · 21c
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for ACOX3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ACOX3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCTACCTGAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    ACOX3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    Mesendoderm-like cells (Generation of mesend...)
    Definitive endoderm-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See ACOX3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ACOX3

    SOURCE GeneReport for Unigene cluster: Hs.479122
        SABiosciences Expression via Pathway-Focused PCR Arrays including ACOX3: 
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              PPAR Targets in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ACOX3 gene from 8/22 species (see all 22)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Acox31 , 5 acyl-Coenzyme A oxidase 3, pristanoyl1, 5 76.19(n)1
    73.43(a)1
      5 (18.32 cM)5
    809111  NM_030721.21  NP_109646.21 
     355830405 
    chicken
    (Gallus gallus)
    Aves ACOX31 acyl-CoA oxidase 3, pristanoyl 65.41(n)
    65.55(a)
      422869  XM_420814.3  XP_420814.3 
    lizard
    (Anolis carolinensis)
    Reptilia ACOX36
    --
    66(a)
    1 ↔ 1
    GL343236.1(1658704-1685580)
    zebrafish
    (Danio rerio)
    Actinopterygii wufj81d022 Danio rerio cDNA clone MGC64087 IMAGE6794774, complete more 74.75(n)    BC054613.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG175443
    CG95271
    pristanoyl-CoA oxidase3
    CG95271
    42(a)
    (best of 2)3
    52.28(n)1
    44.96(a)1
      37D43
    338981  NM_135183.31  NP_609027.31 
    worm
    (Caenorhabditis elegans)
    Secernentea F58F9.71 , 3 acyl-coenzyme A oxidase3
    Protein F58F9.71
    40(a)3
    47.73(n)1
    42.08(a)1
      IV(6245587-6248667)3
    1773861  NM_068542.31  NP_500943.11 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ACX61 acyl-CoA oxidase 45.43(n)
    36.29(a)
      837141  NM_100512.2  NP_172120.2 
    rice
    (Oryza sativa)
    Liliopsida Os06g03545001 hypothetical protein 46.07(n)
    38.55(a)
      4340986  NM_001064126.1  NP_001057591.1 


    ENSEMBL Gene Tree for ACOX3 (if available)
    TreeFam Gene Tree for ACOX3 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ACOX3 gene
    ACOX22  ACOX12  ACOXL2  
    3 SIMAP similar genes for ACOX3 using alignment to 2 protein entries:     ACOX3_HUMAN (see all proteins):
    ACOX2    ACOX1    ACOXL

    ACOX3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for ACOX3
         1 CNV: 4376
         2 Indels: 46704 27729
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ACOX3
    DNA2.0 Custom Variant and Variant Library Synthesis for ACOX3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ACOX3 for disorders           About GeneDecksing

    OMIM gene information: 603402    OMIM disorders: --

    6 diseases for ACOX3:    About MalaCards
    acyl-coa dehydrogenase    zellweger syndrome    mutism    prostate cancer
    prostatitis    leukemia

    2 diseases from the University of Copenhagen DISEASES database for ACOX3:
    Mutism     Zellweger syndrome

    1 Novoseek disease relationship for ACOX3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zellweger syndrome 79.9 2 2241949 (1), 1770789 (1)

    Human Genome Epidemiology (HuGE) Navigator: ACOX3 (2 documents)

    Export disorders for ACOX3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ACOX3 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with ACOX3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evidence for the existence of a pristanoyl-CoA oxidase gene in man. (PubMed id 9271077)1, 2, 3, 9 Vanhooren J.C.T.... van Veldhoven P.P. (1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer. (PubMed id 15599942)1, 9 Zha S....Isaacs W.B. (2005)
    4. The CoA esters of 2-methyl-branched chain fatty acids and of the bile acid intermediates di- and trihydroxycoprostanic acids are oxidized by one single peroxisomal branched chain acyl-CoA oxidase in human liver and kidney. (PubMed id 8387517)1, 9 Vanhove G.F....Mannaerts G.P. (1993)
    5. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    6. Association between SNP-genotype and chronic lymphocy tic leukemia outcome in a randomized chemotherapy trial. (PubMed id 21659360)1 Wade R....Houlston R.S. (2011)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PubMed id 20677014)1 Shimada M....Tokunaga K. (2010)
    9. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (2010)
    10. Large-scale proteomics analysis of the human kinome. (PubMed id 19369195)2 Oppermann F.S.... Daub H. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 8310 HGNC: 121 AceView: ACOX3 Ensembl:ENSG00000087008 euGenes: HUgn8310
    ECgene: ACOX3 Kegg: 8310 H-InvDB: ACOX3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ACOX3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ACOX3 gene:
    Search GeneIP for patents involving ACOX3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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