Aliases for ACOX3 Gene
External Ids for ACOX3 Gene
Previous GeneCards Identifiers for ACOX3 Gene
Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined. [provided by RefSeq, Jul 2008]
GeneCards Summary for ACOX3 Gene
ACOX3 (Acyl-CoA Oxidase 3, Pristanoyl) is a Protein Coding gene. Among its related pathways are Peroxisome and Fatty acid metabolism. GO annotations related to this gene include receptor binding and oxidoreductase activity, acting on the CH-CH group of donors. An important paralog of this gene is ACOX1.
UniProtKB/Swiss-Prot for ACOX3 Gene
Oxidizes the CoA-esters of 2-methyl-branched fatty acids.