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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ACOX3 Gene

protein-coding GIFtS: 64
GCID: GC04M008368

acyl-CoA oxidase 3, pristanoyl

(Previous names: acyl-Coenzyme A oxidase 3, pristanoyl )

Explore 6 diseases affiliated with
ACOX3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Acyl-CoA Oxidase 3, Pristanoyl¹ ²		Peroxisomal Acyl-Coenzyme A Oxidase 3²
Acyl-Coenzyme A Oxidase 3, Pristanoyl¹ ²		BRCOX³
Branched-Chain Acyl-CoA Oxidase² ³		EC 1.3.3.6³
Pristanoyl-CoA Oxidase² ³		PRCOX³
BRCACox² ³

External Ids:	HGNC: 121¹	Entrez Gene: 8310²	Ensembl: ENSG00000087008⁷	OMIM: 603402⁵	UniProtKB: O15254³

Export aliases for ACOX3 gene to outside databases

Previous GC identifers: GC04M008343 GC04M008549 GC04M008561 GC04M008486 GC04M008287

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ACOX3:

Acyl-Coenzyme A oxidase 3 also know as pristanoyl -CoA oxidase (ACOX3)is involved in the desaturation of 2-methyl

branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver

such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme

activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting

C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific

developmental stages or in a tissue specific manner in tissues that have not yet been examined. (provided by RefSeq,

Jul 2008)

UniProtKB/Swiss-Prot: ACOX3_HUMAN, O15254

Function: Oxidizes the CoA-esters of 2-methyl-branched fatty acids (By similarity)

Gene Wiki entry for ACOX3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000004.11 NC_018915.1 NT_006051.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ACOX3 gene promoter:
TBP RFX1 Pax-2 Pax-2a XBP-1 HNF-3beta CREB TFIID deltaCREB COMP1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): ACOX3 promoter sequence

Search SABiosciences Chromatin IP Primers for ACOX3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACOX3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p15.3 Ensembl cytogenetic band: 4p16.1 HGNC cytogenetic band: 4p15.3

ACOX3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACOX3 gene location

GeneLoc information about chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04M008368: view genomic region (about GC identifiers)

Start:	8,368,009 bp from pter	End:	8,442,452 bp from pter
Size:	74,444 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ACOX3_HUMAN, O15254 (See protein sequence)

Recommended Name: Peroxisomal acyl-coenzyme A oxidase 3

Size: 700 amino acids; 77629 Da

Cofactor: FAD (By similarity)

Subcellular location: Peroxisome (Potential)

Secondary accessions: Q96AJ8

Alternative splicing: 2 isoforms: O15254-1 O15254-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ACOX3: NX_O15254

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_O15254

ACOX3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001095137.1 NP_003492.2

ENSEMBL proteins:

ENSP00000413994 ENSP00000348775 ENSP00000421625 ENSP00000427321

Reactome Protein details: O15254
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	Uscn Proteins for ACOX3

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	IEA	--
GO:0005777	peroxisome	IDA	8993592
GO:0005782	peroxisomal matrix	TAS	--

ACOX3 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for ACOX3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ACOX3 for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR006090 Acyl-CoA_Oxase/DH_1

IPR012258 Acyl-CoA_oxidase

IPR009100 AcylCoA_DH/oxidase

IPR006091 Acyl-CoA_Oxase/DH_cen-dom

IPR002655 Acyl-CoA_oxidase_C

Graphical View of Domain Structure for InterPro Entry O15254

ProtoNet protein and cluster: O15254

1 Blocks protein family: IPB002655 Acyl-CoA oxidase

UniProtKB/Swiss-Prot: ACOX3_HUMAN, O15254

Similarity: Belongs to the acyl-CoA oxidase family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ACOX3_HUMAN, O15254

Function: Oxidizes the CoA-esters of 2-methyl-branched fatty acids (By similarity)

Catalytic activity: Acyl-CoA + O(2) = trans-2,3-dehydroacyl-CoA + H(2)O(2)

Genatlas biochemistry entry for ACOX3:

branched-chain acyl-CoA oxidase 3,peroxisomal,acting on the CoA-esters of pristanic acid and straight chain mono-and

dicarboxy fatty acids,expression below detection limit in man,extremely weakly expressed in liver,may be expressed

under special conditions and tissues so far not examined

Enzyme Number (IUBMB): EC 1.3.3.6¹

miRNA Products:		OriGene 3'-UTR Clone (see all 2): ACOX3 Browse MicroRNA Expression Plasmids
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACOX3

Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003995	acyl-CoA dehydrogenase activity	IEA	--
GO:0003997	acyl-CoA oxidase activity	--	--
GO:0005102	receptor binding	IPI	--
GO:0016402	pristanoyl-CoA oxidase activity	TAS	--
GO:0050660	flavin adenine dinucleotide binding	IEA	--

ACOX3 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for ACOX3:

Decreased melanin production

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Metabolism

	Metabolism	1.00			Metabolism of lipids and lipoproteins	0.34
	Metabolic pathways	0.38

Peroxisomal lipid metabolism

Peroxisomal lipid metabolism

1.00

Beta-oxidation of pristanoyl-CoA

0.40

Peroxisome

Peroxisome

1.00

PPAR signaling pathway

PPAR signaling pathway

1.00

Biosynthesis of unsaturated fatty acids

Biosynthesis of unsaturated fatty acids

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

4 Reactome Pathways for ACOX3

	Beta-oxidation of pristanoyl-CoA
	Metabolism
	Peroxisomal lipid metabolism
	Metabolism of lipids and lipoproteins

5/6 Kegg Pathways (Kegg details for ACOX3) (see all 6):

	Fatty acid metabolism
	alpha-Linolenic acid metabolism
	Biosynthesis of unsaturated fatty acids
	Metabolic pathways
	PPAR signaling pathway

UniProtKB/Swiss-Prot: ACOX3_HUMAN, O15254

Pathway: Lipid metabolism; peroxisomal fatty acid beta-oxidation

ACOX3 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ACOX3

STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

5/25 Interacting proteins for ACOX3 (O15254^{2, 3} ENSP00000348775⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 25)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SMURF2	Q9HAU4²^,³	MINT-61801 I2D: score=3
SLC2A4	P14672³	I2D: score=1
ACAA1	ENSP00000333664⁴	STRING: ENSP00000333664
ACAA2	ENSP00000285093⁴	STRING: ENSP00000285093
ACAT1	ENSP00000265838⁴	STRING: ENSP00000265838

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006631	fatty acid metabolic process	--	--
GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	TAS	--
GO:0044255	cellular lipid metabolic process	TAS	--
GO:0044281	small molecule metabolic process	TAS	--

ACOX3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

ACOX3 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ACOX3

10/42 HMDB Compounds for ACOX3 (see all 42) About this table

Compound	Synonyms	CAS #	PubMed Ids
(2E)-Decenoyl-CoA	(E)-S-2-decenoate Coenzyme A (see all 15)	10018-95-8	--
(2E)-Dodecenoyl-CoA	2-trans-Dodecenoyl-Coenzyme A (see all 4)	1066-12-2	--
(2E)-Hexadecenoyl-CoA	trans-2-Hexadecenoyl-CoA (see all 4)	4460-95-1	--
(2E)-Octenoyl-CoA	(E)-S-2-octenoate Coenzyme A (see all 16)	10018-94-7	--
(2E)-Tetradecenoyl-CoA	(2E)-Tetradecenoyl-Coenzyme A (see all 8)	38795-33-4	--
(2S,6R,10R)-Trimethyl-hendecanoyl-CoA	((2S),(6R),10)-trimethylundecanoyl-CoA (see all 8)	--	--
2-Methylbutyryl-CoA	2-methylbutanoyl-CoA (see all 11)	6712-02-3	--
2-Methylhexanoyl-CoA	2-Methylhexanoyl-CoEnzyme A (see all 5)	--	--
20-CoA-20-oxo-leukotriene B4	CoA-20-COOH-LTB(,4) (see all 2)	--	--
3Z-dodecenoyl-CoA	S-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-dodec-3-enethioate (see all 4)	2152-91-2	--

6 Novoseek chemical compound relationships for ACOX3 gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
pristanic acid	95.5	3	10709653 (1), 8387517 (1), 9803880 (1)
acyl-coa	83.8	6	9053547 (1), 8556358 (1), 9803880 (1)
phytanic acid	83.2	1	1770789 (1)
tripeptide	54.1	1	8706733 (1)
sterol	42.5	3	11330072 (1), 9803880 (1)
fatty acid	27.5	2	15599942 (1)

Search CenterWatch for drugs/clinical trials and news about ACOX3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ACOX3 gene (2 alternative transcripts):

NM_001101667.1 NM_003501.2

Unigene Cluster for ACOX3:

Acyl-CoA oxidase 3, pristanoyl

Hs.479122 [show with all ESTs]

Unigene Representative Sequence: BX640768

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000512411 ENST00000515797 ENST00000413009(uc003gld.4) ENST00000356406(uc010idk.3 uc003glc.4)

ENST00000503233 ENST00000510365 ENST00000508302 ENST00000514423

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Additional cDNA sequence:

AK225080.1 AK313242.1 BC017053.1 BX640768.1 Y11411.1

10 DOTS entries:

DT.100742019 DT.315013 DT.95141073 DT.97841659 DT.101966593 DT.95261316 DT.75102844 DT.86848005

DT.91740564 DT.95155153

24/141 AceView cDNA sequences (see all 141):

CF132142 CA438485 BM837705 BU728389 AI436007 BM010643 BM773520 BX364074

Z40378 BU857907 BF724168 AI571140 BM682926 Z45527 AU132016 AU141142

AU131606 CR609446 BQ436455 AI435950 R32150 BF055976 CA306669 F09801

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ACOX3 (see all 8) About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4	^	5	^	6	^	7	^	8a	·	8b	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16a	·	16b	^	17	^	18	^	19a	·	19b	^	20	^	21a	·
SP1:																																					-						-		-
SP2:					-		-		-																												-						-		-		-
SP3:
SP4:											-
SP5:																																											-		-

ExUns:	21b	·	21c
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for ACOX3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ACOX3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTACCTGAT

About this image

ACOX3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Mesendoderm-like cells (Generation of mesend...)

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ACOX3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ACOX3

SOURCE GeneReport for Unigene cluster: Hs.479122

SABiosciences Expression via Pathway-Focused PCR Arrays including ACOX3:

Fatty Acid Metabolism in human mouse rat

PPAR Targets in human mouse rat

Molecular Toxicology PathwayFinder 384HT in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for ACOX3 gene from 8/22 species (see all 22) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Acox3^{1 , 5}	acyl-Coenzyme A oxidase 3, pristanoyl^{1, 5}	76.19(n)¹ 73.43(a)¹		5 (18.32 cM)⁵ 80911¹ NM_030721.2¹ NP_109646.2¹ 35583040⁵
chicken (Gallus gallus)	Aves	ACOX3¹	acyl-CoA oxidase 3, pristanoyl	65.41(n) 65.55(a)		422869 XM_420814.3 XP_420814.3
lizard (Anolis carolinensis)	Reptilia	ACOX3⁶	--	66(a)	1 ↔ 1	GL343236.1(1658704-1685580)
zebrafish (Danio rerio)	Actinopterygii	wufj81d02²	Danio rerio cDNA clone MGC64087 IMAGE6794774, complete more	74.75(n)		BC054613.1
fruit fly (Drosophila melanogaster)	Insecta	CG17544³ CG9527¹	pristanoyl-CoA oxidase³ CG9527¹	42(a) (best of 2)³ 52.28(n)¹ 44.96(a)¹		37D4³ 33898¹ NM_135183.3¹ NP_609027.3¹
worm (Caenorhabditis elegans)	Secernentea	F58F9.7^{1 , 3}	acyl-coenzyme A oxidase³ Protein F58F9.7¹	40(a)³ 47.73(n)¹ 42.08(a)¹		IV(6245587-6248667)³ 177386¹ NM_068542.3¹ NP_500943.1¹
thale cress (Arabidopsis thaliana)	eudicotyledons	ACX6¹	acyl-CoA oxidase	45.43(n) 36.29(a)		837141 NM_100512.2 NP_172120.2
rice (Oryza sativa)	Liliopsida	Os06g0354500¹	hypothetical protein	46.07(n) 38.55(a)		4340986 NM_001064126.1 NP_001057591.1

ENSEMBL Gene Tree for ACOX3 (if available)
TreeFam Gene Tree for ACOX3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ACOX3 gene

ACOX2² ACOX1² ACOXL²

3 SIMAP similar genes for ACOX3 using alignment to 2 protein entries: ACOX3_HUMAN (see all proteins):

ACOX2 ACOX1 ACOXL

ACOX3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
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Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ACOX3
1 CNV: 4376
2 Indels: 46704 27729

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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ACOX3 for disorders           About GeneDecksing

OMIM gene information: 603402    OMIM disorders: --

6 diseases for ACOX3:    About MalaCards

acyl-coa dehydrogenase zellweger syndrome mutism prostate cancer

prostatitis leukemia

2 diseases from the University of Copenhagen DISEASES database for ACOX3:

Mutism Zellweger syndrome

1 Novoseek disease relationship for ACOX3 gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
zellweger syndrome	79.9	2	2241949 (1), 1770789 (1)

Human Genome Epidemiology (HuGE) Navigator: ACOX3 (2 documents)

Export disorders for ACOX3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for ACOX3 gene, integrated from 9 sources (see all 28):
(articles sorted by number of sources associating them with ACOX3)

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Evidence for the existence of a pristanoyl-CoA oxidase gene in man. (PubMed id 9271077)^{1, 2, 3, 9} Vanhooren J.C.T.... van Veldhoven P.P. (1997)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer. (PubMed id 15599942)^{1, 9} Zha S....Isaacs W.B. (2005)
The CoA esters of 2-methyl-branched chain fatty acids and of the bile acid intermediates di- and trihydroxycoprostanic acids are oxidized by one single peroxisomal branched chain acyl-CoA oxidase in human liver and kidney. (PubMed id 8387517)^{1, 9} Vanhove G.F....Mannaerts G.P. (1993)
Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)¹ Udeshi N.D....Carr S.A. (2012)
Association between SNP-genotype and chronic lymphocy tic leukemia outcome in a randomized chemotherapy trial. (PubMed id 21659360)¹ Wade R....Houlston R.S. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PubMed id 20677014)¹ Shimada M....Tokunaga K. (2010)
Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)¹ Hendrickson S.L....O'Brien S.J. (2010)
Large-scale proteomics analysis of the human kinome. (PubMed id 19369195)² Oppermann F.S.... Daub H. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
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Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 8310	HGNC: 121	AceView: ACOX3	Ensembl:ENSG00000087008	euGenes: HUgn8310
ECgene: ACOX3	Kegg: 8310	H-InvDB: ACOX3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ACOX3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ACOX3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ACOX3 gene:
Search GeneIP for patents involving ACOX3

GeneCards and IP:
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ACOX3 Gene

acyl-CoA oxidase 3, pristanoyl

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ACOX3 Gene

acyl-CoA oxidase 3, pristanoyl

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