Aliases for ACOX2 Gene
- Acyl-CoA Oxidase 2 2 3 5
- 3-Alpha,7-Alpha,12-Alpha-Trihydroxy-5-Beta-Cholestanoyl-CoA 24-Hydroxylase 2 3 4
- Trihydroxycoprostanoyl-CoA Oxidase 2 3 4
- 3-Alpha,7-Alpha,12-Alpha-Trihydroxy-5-Beta-Cholestanoyl-CoA Oxidase 3 4
- Acyl-Coenzyme A Oxidase 2, Branched Chain 2 3
- Acyl-CoA Oxidase 2, Branched Chain 2 3
- Branched Chain Acyl-CoA Oxidase 2 3
- THCA-CoA Oxidase 3 4
External Ids for ACOX2 Gene
Previous GeneCards Identifiers for ACOX2 Gene
The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children. [provided by RefSeq, Mar 2009]
GeneCards Summary for ACOX2 Gene
ACOX2 (Acyl-CoA Oxidase 2) is a Protein Coding gene. Among its related pathways are PPAR signaling pathway and Peroxisome. GO annotations related to this gene include receptor binding and oxidoreductase activity, acting on the CH-CH group of donors. An important paralog of this gene is ACOX1.
UniProtKB/Swiss-Prot for ACOX2 Gene
Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids.