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ACOT7 Gene

protein-coding   GIFtS: 57

GC01M006259
acyl-CoA thioesterase 7
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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Aliases &
Descriptions
for ACOT7

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
ACH1 1, 2
ACT 1, 2
BACH 1, 2, 3, 5
CTE-II 1, 2, 3
CTE-IIa 3
EC 3.1.2.2 3
LACH 2, 5
LACH1 1, 2
MGC1126 1, 2
OTTHUMP00000001410 2
OTTHUMP00000001413 2
OTTHUMP00000001414 2
hBACH 1, 2
Descriptions
Brain acyl-CoA hydrolase 2, 3
Long chain acyl-CoA thioester hydrolase 2, 3
acyl-CoA thioesterase 2 2
acyl-CoA thioesterase 7 2, 3
acyl-CoA thioesterase, long chain 2
brain acyl CoA hydrolase 2
cytosolic acyl coenzyme A thioester hydrolase 2
External Ids
HGNC: 241571
Entrez Gene: 113322
UniProtKB: O001543
Ensembl: ENSG000000970217
Search outside databases for aliases for ACOT7 gene

Summaries
for ACOT7

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for ACOT7:
This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA
thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may
be associated with mesial temporal lobe epilepsy. Alternatively spliced transcript variants
encoding distinct isoforms with different subcellular locations have been characterized. [provided
by RefSeq]

UniProtKB/Swiss-Prot: BACH_HUMAN, O00154
Function: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs
to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular
levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in
brain. May play a regulatory role by modulating the cellular levels of fatty acyl-CoA ligands for
certain transcription factors as well as the substrates for fatty acid metabolizing enzymes,
contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with
chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA

Gene Wiki entry for ACOT7

Genomic Location
for ACOT7

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ACOT7 gene  

Entrez Gene cytogenetic band: 1p36.31-p36.11   Ensembl cytogenetic band:  1p36.31   HGNC cytogenetic band: 1p36

ACOT7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M006259:     (about GC identifiers)

Start:
 6,246,919 bp from pter
End:
 6,376,413 bp from pter
Size:
 129,495 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000001.9  NT_021937.18  

Proteins
for ACOT7

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: BACH_HUMAN, O00154 (See protein sequence)
Recommended Name: Cytosolic acyl coenzyme A thioester hydrolase  
Size: 380 amino acids; 41796 Da
Subunit: Homodimer (Probable)
Subcellular location: Isoform 4: Cytoplasm
Subcellular location: Isoform 6: Cytoplasm
Subcellular location: Isoform 1: Mitochondrion
Subcellular location: Isoform 5: Mitochondrion
Sequence caution: Sequence=AAB61211.1; Type=Frameshift; Positions=371;
PDB structures from and Proteopedia :
2QQ2 (3D)    
Secondary accessions: A8K0K7 O43703 Q53Y78 Q5JYL2 Q5JYL3 Q5JYL4 Q5JYL5 Q5JYL6 Q5TGR4 Q9UJM9 Q9Y539
Q9Y540
Alternative splicing: 6 isoforms:  O00154-1   O00154-2   O00154-3   O00154-4   O00154-5   O00154-6   

REFSEQ proteins (4 alternative transcripts): 
NP_009205.3  NP_863654.1  NP_863655.1  NP_863656.1  


ENSEMBL proteins: 
ENSP00000367089 ENSP00000367091 ENSP00000367073 ENSP00000367076 ENSP00000354615 ENSP00000367086 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich  
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Recombinant Proteins from Abcam (ACOT7)
Human Recombinant Proteins from Abnova (ACOT7)
              OriGene Purified Recombinant Human Protein: ACOT7 

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0005737 cytoplasm TAS10578051
GO:0005739 mitochondrion IEA--
About this table

Antibodies for ACOT7: 
Browse Antibodies Central at Invitrogen
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Sigma-Aldrich Antibodies for ACOT7
Browse R&D Systems for Antibodies
Antibodies from Abcam (ACOT7), each with their AbpromiseSM
Monoclonal and Polyclonal Antibodies from Abnova (ACOT7)
Novus Biologicals Antibody for ACOT7

Assays for ACOT7: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

Protein Domains/
Families
for ACOT7

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
1 InterPro domain/family:
 IPR006683 Thioestr_supf


   GeneDecks  ACOT7 for the domains selected above  
About GeneDecksing

Graphical View of Domain Structure for InterPro Entry O00154

ProtoNet protein and cluster: O00154

UniProtKB/Swiss-Prot: BACH_HUMAN, O00154
Similarity: Contains 2 acyl coenzyme A hydrolase domains

Gene Function
for ACOT7

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (ACOT7)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 6): NM_007274

              Applied Biosystems Silencer® siRNAs for ACOT7

              Sigma-Aldrich siRNA for ACOT7  
                     Sigma-Aldrich shRNA for ACOT7  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Invitrogen Clones for ACOT7
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_007274
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_007274
                                 untagged cDNA clones in CMV expression vector (see all 6): NM_007274 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_181864

UniProtKB/Swiss-Prot: BACH_HUMAN, O00154
Function: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs
to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular
levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in
brain. May play a regulatory role by modulating the cellular levels of fatty acyl-CoA ligands for
certain transcription factors as well as the substrates for fatty acid metabolizing enzymes,
contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with
chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA
Catalytic activity: Palmitoyl-CoA + H(2)O = CoA + palmitate
Enzyme Number (IUBMB): EC 3.1.2.2 

1 MGI phenotypic allele for Acot7 (no phenotypes)


4 Gene Ontology (GO) molecular function terms (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0000062 acyl-CoA binding TAS10578051
GO:0004091 carboxylesterase activity IEA--
GO:0016290 palmitoyl-CoA hydrolase activity IEA--
GO:0016787 hydrolase activity IEA--
About this table

Pathways & Interactions
for ACOT7

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Invitrogen iPath™ Online BioAtlas - Pathways for ACOT7 (Maps provided by GeneGo):
 Fatty acid synthesis II
 Cholesterol metabolism III. Biosynthesis of bile acid

   GeneDecks  ACOT7 for the pathways selected above  
About GeneDecksing

1 Kegg Pathway  (Kegg details for ACOT7):
 hsa01040 Biosynthesis of unsaturated fatty acids

   GeneDecks  ACOT7 for the pathways selected above  
About GeneDecksing

5/11 Interacting proteins for ACOT7 (ENSP000003670863 O001542) via UniProtKB, MINT, and/or STRING (see all 11 )
InteractantInteraction Details
GeneCardExternal ID(s)
ATXN1P542532MINT-2869773
C16orf35ENSP000002623133STRING (score=.913)
MAFENSP000003270483STRING (score=.905)
MAFGENSP000003503693STRING (score=.904)
SREBF2ENSP000003544763STRING (score=.863)
About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO IDQualified GO termEvidencePubMed IDs
GO:0006629 lipid metabolic process TAS10578051
About this table

Drugs & Compounds
for ACOT7

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ACOT7
2 Novoseek chemical compound relationships for ACOT7 gene
Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
acyl-coa 79.89 7 12435388 (2), 10578051 (1), 15638818 (1), 8631842 (1)
fatty acid 37.94 5 17514357 (2)
About this table


Transcripts
for ACOT7

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (ACOT7)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 6): NM_007274

              Sigma-Aldrich siRNA for ACOT7  
                     Sigma-Aldrich shRNA for ACOT7  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_007274  NM_181864  NM_181865  NM_181866  

REFSEQ mRNAs for ACOT7 gene (4 alternative transcripts): 

NM_007274.3   NM_181864.2   NM_181865.2   NM_181866.2   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_007274  NM_181864  NM_181865  NM_181866  

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_007274
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_007274
                                 untagged cDNA clones in CMV expression vector (see all 6): NM_007274 

Additional cDNA sequence: 

AB074417.1 AB074418.1 AB074419.1 AK057168.1 AK289572.1 AK290097.1 AK291583.1 AK292202.1 
AK300831.1 AK304465.1 BC017365.2 BT006888.1 CR593786.1 CR594456.1 CR595220.1 CR597165.1 
CR599443.1 CR599569.1 CR603255.1 CR604226.1 CR605522.1 CR606054.1 CR608567.1 CR611815.1 
CR614606.1 CR615031.1 CR617887.1 CR620600.1 CR620739.1 D88894.2 

13 DOTS entries:

DT.449444  DT.100882148  DT.87017261  DT.87017263  DT.100882155  DT.100882133  DT.121351036  DT.95361277 
DT.95361290  DT.121274009  DT.121351044  DT.100882139  DT.121351082 

24/350 AceView cDNA sequences (see all 350 ):

CB138691 CD107361 NM_181863 CR604226 BI858286 BM846520 F12498 BI861417 
BT006888 BM669679 BQ439022 CR595220 CR617887 BM908868 CR620600 BP338388 
CB125794 CR611815 BQ425408 CR620739 AU104967 BI193315 CR615031 CR606054 

highest scoring ESTs for ACOT7:

AA923265 AK057168 AU099272 AW025033 AW327399 AW674832 BC017365 BE260274 BE260742 BE274746 

Unigene Cluster for ACOT7:

Acyl-CoA thioesterase 7
Hs.126137  [show with all ESTs]
Unigene Representative Sequence: BC017365


GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ACOT7 (see all 9 )

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b
SP1:              -     -     -                                               -           -                                       
SP2:              -     -     -                                               -           -     -                                 
SP3:              -     -     -                                               -           -     -     -                           
SP4:                          -                                               -           -     -     -                           
SP5:                                                                          -           -     -     -                           

About this scheme

ECgene alternative splicing isoforms for ACOT7

6 Ensembl transcripts including schematic representations:
ENST00000377858  ENST00000377860  ENST00000377842  ENST00000377845  ENST00000361521  ENST00000377855  

Expression
for ACOT7

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ACOT7 expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for ACOT7

1 / 2 / 3

6 probe-sets matching ACOT7 gene


Affymetrix
probe-set		 Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

75352_s_at2, 3 U95-D 2 1.00 0.94 0.99 1.08 AW025033 0.80 1.00 0.91 1

37945_at2, 3 U95-A 1 0.69 1.00 0.97 0.92 U91316 0.80 1.00 0.91 1

208002_s_at2, 3 U133-A 2 1.00 0.86 -- -- NM_007274 0.60 1.00 0.82 1

215728_s_at2 U133-A 2 1.00 0.77 -- -- -- -- -- -- --

208002_s_at2 U133Plus2 2 1.00 0.86 -- -- -- -- -- -- --

215728_s_at2 U133Plus2 2 1.00 0.77 -- -- -- -- -- -- --
About this table
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: GCAACGGGCC

SOURCE GeneReport for Unigene cluster: Hs.126137

UniProtKB/Swiss-Prot: BACH_HUMAN, O00154
Tissue specificity: Isoform 4 is expressed exclusively in brain

Orthologs
for ACOT7

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section
Orthologs for ACOT7 gene from 5/9 species (see all 9 )
Organism Gene Locus Description Human
Similarity		 NCBI accessions
dog
(Canis familiaris)		 ACOT71   -- acyl-CoA thioesterase 7 90.97(n)
98.44(a)		 479589  XM_536727.2  XP_536727.2 
chimpanzee
(Pan troglodytes)		 ACOT71   -- acyl-CoA thioesterase 7 99.21(n)
99.47(a)		 745616  XM_001155887.1  XP_001155887.1 
cow
(Bos taurus)		 ACOT71   -- acyl-CoA thioesterase 7 89.85(n)
94.03(a)		 514788  NM_001075682.1  NP_001069150.1 
rat
(Rattus norvegicus)		 Acot71   -- acyl-CoA thioesterase 7 87.8(n)
94.05(a)		 26759  NM_013214.3  NP_037346.1 
mouse
(Mus musculus)		 Acot71, 5 45
 acyl-CoA thioesterase 71, 5 87.8(n)1
94.64(a)1		 700251  NM_133348.11  NP_579926.11 
 AB0498215  AB0884115  (see all 26)
About this table        Species with no ortholog for ACOT7

ENSEMBL Gene Tree for ACOT7

Paralogs
for ACOT7

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Paralogs for ACOT7 gene
LOC3449672  

Pseudogenes
1 related pseudogene


SNPs/Variants
for ACOT7

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section


10/733 NCBI SNPs in ACOT7 are shown (see all 733 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 166)
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr 1 posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
------------
rs38277171,2
A,C,F,H6343077(-) CAGGAA/TGATGG 4 -- int1 ng319Minor allele frequency- T:0.30NA EU EA WA 736
--
rs75125321,2
A,C,F,H6344283(+) cactaG/Ctgaaa 3 -- ng31 int18Minor allele frequency- C:0.39EU EA WA 840
rs66878301,2
A,C,F,H6368795(+) GCTGCG/CGGGAA 2 -- int1 ng314Minor allele frequency- C:0.07EU EA WA 418
rs37894631,2
A,C,F,H6370161(-) CCTGCA/GTGGGA 2 -- int1 ng315Minor allele frequency- G:0.08EA EU WA 1910
--
rs66632991,2
A,F,H6377181(+) CAGTCA/CAAGTC 1 -- ng314Minor allele frequency- C:0.13EU EA WA 412
rs66605001,2
F,H6345346(+) GTAGGG/ATCAGA 3 -- ng31 int14Minor allele frequency- A:0.11EU EA WA 412
rs49085471,2
F,H6343718(+) aaggaT/Cggaaa 3 -- int1 ng314Minor allele frequency- C:0.05EU EA WA 420
rs22729891,2
F6376756(-) CCCAGT/AAAAAG 1 -- ng31 ese31Minor allele frequency- A:0.04EA 1284
rs10766991,2
F6342494(-) GAGGCC/TGGCGG 4 -- int1 ng311Minor allele frequency- T:0.06NA 90
rs10441541,2
C6246947(-) CCAGCA/CCCACT 4 -- ut311Minor allele frequency- C:0.00MN 184
About this table

HapMap Linkage Disequilibrium images for ACOT7 (up to first 250kb)

Disorders & Mutations
for ACOT7

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

 OMIM: 602587

Medical News
for ACOT7

(Possibly Related Articles in Doctor's Guide)
About This Section

   --

Publications
for ACOT7

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
About This Section

10/16 PubMed articles for ACOT7 gene (see all 16 ):

Search for ACOT7

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing ACOT7

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section
Entrez Gene: 11332 HGNC: 24157 AceView: BACH Ensembl:ENSG00000097021 euGenes: HUgn11332
ECgene: ACOT7 H-InvDB: ACOT7

Other Databases showing ACOT7

(According to HUGE)
About This Section

   --

Specialized Databases showing ACOT7

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
ATLAS Chromosomes in Cancer entry for ACOT7 Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies
for ACOT7

(Available from WIS Yeda, Salk, Tufts)
About This Section

  --

Services
for ACOT7

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for ACOT7:
 TaqMan ® Gene Expression Assays
 TaqMan ® Genotyping Assays
  Free SNP selection tool



  Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
  Invitrogen Antibodies  Invitrogen Assays
  Invitrogen Clones  Invitrogen Q-PCR Products
  Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
  Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ACOT7-related products

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services


 Predesigned and custom siRNAs for ACOT7 Antibodies for ACOT7
 Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for ACOT7 Browse small molecules at Sigma-Aldrich
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 Tagged/untagged cDNA clones
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 Purified proteins from HEK293T cells
 Western blot validated antibodies
 shRNA in GFP-retroviral vector
 Search Tocris compounds for ACOT7




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