Aliases for ACOT4 Gene
External Ids for ACOT4 Gene
Previous GeneCards Identifiers for ACOT4 Gene
GeneCards Summary for ACOT4 Gene
ACOT4 (Acyl-CoA Thioesterase 4) is a Protein Coding gene. Diseases associated with ACOT4 include Early-Onset Familial Alzheimer Disease. Among its related pathways are Metabolism and Fatty acid elongation. GO annotations related to this gene include receptor binding and palmitoyl-CoA hydrolase activity. An important paralog of this gene is ACOT2.
UniProtKB/Swiss-Prot for ACOT4 Gene
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs.