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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ACOT11 Gene

protein-coding GIFtS: 53
GCID: GC01P055007

acyl-CoA thioesterase 11

(Previous names: thioesterase, adipose associated )
(Previous symbol: THEA)

Explore 4 diseases affiliated with
ACOT11 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Acyl-CoA Thioesterase 11¹ ² ³		Brown Fat-Inducible Thioesterase² ³
BFIT¹ ² ³ ⁵		BFIT1¹ ⁵
THEA¹ ² ³ ⁵		Acyl-Coenzyme A Thioesterase 11²
KIAA0707¹ ³ ⁵		StAR-Related Lipid Transfer (START) Domain Containing 14²
STARD14¹ ²		START Domain Containing 14²
THEM1¹ ²		Thioesterase Superfamily Member 1²
Thioesterase, Adipose Associated¹ ²		EC 3.1.2.-³
Acyl-CoA Thioester Hydrolase 11² ³		BFIT2⁵
Adipose-Associated Thioesterase² ³		EC 3.1.2.1⁸

External Ids:	HGNC: 18156¹	Entrez Gene: 26027²	Ensembl: ENSG00000162390⁷	OMIM: 606803⁵	UniProtKB: Q8WXI4³

Export aliases for ACOT11 gene to outside databases

Previous GC identifers: GC01P054720 GC01P054786 GC01P053127

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ACOT11:

This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids

to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue

is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog

has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase

11 in obesity. Alternative splicing results in transcript variants. (provided by RefSeq, Nov 2010)

UniProtKB/Swiss-Prot: ACO11_HUMAN, Q8WXI4

Function: Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates

Gene Wiki entry for ACOT11

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_032977.9

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ACOT11 gene promoter:
USF1 C/EBPbeta Nkx2-5 E47 POU2F1 USF-1 POU2F1b POU2F1a POU2F1c En-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ACOT11 promoter sequence

Search SABiosciences Chromatin IP Primers for ACOT11

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACOT11

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32.3 Ensembl cytogenetic band: 1p32.3 HGNC cytogenetic band: 1p32.3

ACOT11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACOT11 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P055007: view genomic region (about GC identifiers)

Start:	55,007,930 bp from pter	End:	55,104,865 bp from pter
Size:	96,936 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ACO11_HUMAN, Q8WXI4 (See protein sequence)

Recommended Name: Acyl-coenzyme A thioesterase 11

Size: 607 amino acids; 68492 Da

Subcellular location: Cytoplasm

Sequence caution: Sequence=BAA31682.1; Type=Erroneous initiation;

1 PDB 3D structure from and Proteopedia for ACOT11:

3FO5 (3D)

Secondary accessions: B1AQ22 D3DQ50 O75187 Q52LP1 Q53ER9 Q96DI1 Q9H883

Alternative splicing: 2 isoforms: Q8WXI4-1 Q8WXI4-2

Explore the universe of human proteins at neXtProt for ACOT11: NX_Q8WXI4

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8WXI4

3 DME Specific Peptides for ACOT11 (Q8WXI4)

RHINSAF

ELVLPPHANH

GNTFGGQIMAWME

ACOT11 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_056362.1 NP_671517.1

ENSEMBL proteins:

ENSP00000340260 ENSP00000360366

Human Recombinant Protein Products:

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	Novus Biologicals ACOT11 Protein Novus Biologicals ACOT11 Lysate
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	Uscn Proteins for ACOT11

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005737	cytoplasm	IC	11696000

ACOT11 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for ACOT11

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ACOT11 for domains About GeneDecksing

3 InterPro domains/families:

IPR006683 Thioestr_supf

IPR023393 START-like_dom

IPR002913 START_lipid-bd_dom

Graphical View of Domain Structure for InterPro Entry Q8WXI4

ProtoNet protein and cluster: Q8WXI4

UniProtKB/Swiss-Prot: ACO11_HUMAN, Q8WXI4

Similarity: Contains 2 acyl coenzyme A hydrolase domains

Similarity: Contains 1 START domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ACO11_HUMAN, Q8WXI4

Function: Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates

Induction: By cold exposure and repressed by heat exposure

Enzyme Numbers (IUBMB): EC 3.1.2.1² EC 3.1.2.-¹

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACOT11

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004091	carboxylesterase activity	IEA	--
GO:0047617	acyl-CoA hydrolase activity	TAS	11696000

ACOT11 for ontologies About GeneDecksing

3 GenomeRNAi human phenotypes for ACOT11:

Decreased DCP1a protein expres

Synthetic lethal with Ras

Upregulation of Wnt/beta-caten

Animal Models:
Mouse knock-out Acot11^tm1Deco for ACOT11
7 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Acot11):

adipose tissue	behavior/neurological	cellular	growth/size	homeostasis/metabolism
immune system	liver/biliary system

ACOT11 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ACOT11

STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

5/12 Interacting proteins for ACOT11 (ENSP00000360366⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 12)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CNST	ENSP00000355470⁴	STRING: ENSP00000355470
DHCR24	ENSP00000360316⁴	STRING: ENSP00000360316
EFCAB2	ENSP00000355480⁴	STRING: ENSP00000355480
FAM151A	ENSP00000306888⁴	STRING: ENSP00000306888
MROH7	ENSP00000396622⁴	STRING: ENSP00000396622

About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006631	fatty acid metabolic process	NAS	11696000
GO:0009266	response to temperature stimulus	ISS	--
GO:0009409	response to cold	ISS	11696000
GO:0035556	intracellular signal transduction	NAS	11696000

ACOT11 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ACOT11

10/32 HMDB Compounds for ACOT11 (see all 32) About this table

Compound	Synonyms	CAS #	PubMed Ids
(2E)-Decenoyl-CoA	(E)-S-2-decenoate Coenzyme A (see all 15)	10018-95-8	--
(2E)-Dodecenoyl-CoA	2-trans-Dodecenoyl-Coenzyme A (see all 4)	1066-12-2	--
(2E)-Hexadecenoyl-CoA	trans-2-Hexadecenoyl-CoA (see all 4)	4460-95-1	--
(2E)-Octenoyl-CoA	(E)-S-2-octenoate Coenzyme A (see all 16)	10018-94-7	--
(2E)-Tetradecenoyl-CoA	(2E)-Tetradecenoyl-Coenzyme A (see all 8)	38795-33-4	--
2-Methylbutyryl-CoA	2-methylbutanoyl-CoA (see all 11)	6712-02-3	--
2-Methylhexanoyl-CoA	2-Methylhexanoyl-CoEnzyme A (see all 5)	--	--
3Z-dodecenoyl-CoA	S-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-dodec-3-enethioate (see all 4)	2152-91-2	--
Acetyl-CoA	S-Acetyl coenzyme A (see all 13)	72-89-9	--
Acrylyl-CoA	Acryloyl coenzyme A (see all 14)	5776-58-9	--

Search CenterWatch for drugs/clinical trials and news about ACOT11 / ACO11

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ACOT11 gene (2 alternative transcripts):

NM_015547.3 NM_147161.3

Unigene Cluster for ACOT11:

Acyl-CoA thioesterase 11

Hs.234786 [show with all ESTs]

Unigene Representative Sequence: AB014607

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000481208 ENST00000498228(uc001cxk.3) ENST00000343744(uc001cxj.2 uc001cxl.2)

ENST00000371316(uc001cxm.2) ENST00000479837 ENST00000492752

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		hsa-miR-877* hsa-miR-196a* hsa-miR-1236 hsa-miR-335
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Additional cDNA sequence:

AB014607.1 AF416921.1 AF416922.1 AK023937.1 AK091112.1 AK223570.1 AL713723.1 BC093844.1

BC093846.1

13 DOTS entries:

DT.102826042 DT.407361 DT.97822196 DT.91679570 DT.97830603 DT.121396772 DT.121396875 DT.121396786

DT.121396810 DT.91679572 DT.95141096 DT.91916523 DT.121396912

24/54 AceView cDNA sequences (see all 54):

AF416922 NM_015547 AU159322 BU632371 CD722495 AI636018 NM_147161 AL713723

AU141870 AK023937 BM015268 BE732224 BX451348 CB152012 AB014607 BX119156

CD637439 BX332767 BQ223248 CK001768 BG427577 BX282220 BM264599 CA389831

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for ACOT11 (see all 12) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	·	2c	·	2d	·	2e	^	3	^	4	^	5	^	6	^	7	^	8a	·	8b	^	9	^	10	^	11a	·	11b	^	12a	·	12b	·	12c	^	13a	·	13b	^	14	^	15	^	16	^
SP1:															-		-		-		-		-																						-						-
SP2:															-		-		-		-		-																						-						-
SP3:																	-		-		-		-
SP4:																					-		-
SP5:					-		-		-		-		-		-		-		-		-		-

ExUns:	17	^	18	^	19	^	20a	·	20b	^	21	^	22	^	23	^	24	^	25
SP1:															-
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for ACOT11

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ACOT11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

ACOT11 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Adipose

Interscapular Brown Adipose Depot

Adipose

Thoracic Perivascular Adipose

Adipose

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ progenitor EN2 (Embryonic Progenitor Cell)

See ACOT11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ACOT11

SOURCE GeneReport for Unigene cluster: Hs.234786

UniProtKB/Swiss-Prot: ACO11_HUMAN, Q8WXI4

Tissue specificity: Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and

brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue

SABiosciences Custom PCR Arrays for ACOT11

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACOT11

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the last universal common ancestor (LUCA).

Orthologs for ACOT11 gene from 5/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	ACOT11¹	acyl-CoA thioesterase 11	76.71(n) 76.66(a)		429108 XM_426664.3 XP_426664.3
lizard (Anolis carolinensis)	Reptilia	ACOT11⁶	--	68(a)	1 ↔ 1	4(104549298-104604062)
African clawed frog (Xenopus laevis)	Amphibia	Xl.8808²	Xenopus laevis transcribed sequence with moderate similarity to protein pirT00351 (H.sapiens) T00351 hypothetical protein KIAA0707 - human (fragment) less	78.53(n)		BX843189.1
zebrafish (Danio rerio)	Actinopterygii	acot11a¹	acyl-CoA thioesterase 11a	66.61(n) 67.7(a)		554842 NM_001099975.2 NP_001093445.1
E. coli (Escherichia coli)	Gamma proteobacteria	yciA⁶	Acyl-CoA esterase, role unknown	19(a)	1 → many	Chromosome(1309872-1310270)

ENSEMBL Gene Tree for ACOT11 (if available)
TreeFam Gene Tree for ACOT11 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ACOT11 gene

ACOT12² ACOT7²

1 SIMAP similar gene for ACOT11 using alignment to 1 protein entry: ACO11_HUMAN:

ACOT12

ACOT11 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs186734886^1,2		--	55011879(+)	`CTCTCA/GTAAGT`	2	--	us2k¹		0	--	--	--	--
rs116641105^1,2		--	55011983(+)	`TCACTG/ATGTGT`	2	--	us2k¹		1		NA	120
rs191147420^1,2		--	55012002(+)	`GCCTCA/GCTTTC`	2	--	us2k¹		0	--	--	--	--
rs142103061^1,2		--	55012006(+)	`CACTTC/TCCTCC`	2	--	us2k¹		0	--	--	--	--
rs139049636^1,2		--	55012093(+)	`GAGAGA/GGTAGG`	2	--	us2k¹		0	--	--	--	--
rs183361979^1,2		--	55012110(+)	`AGCCAG/TGAGCT`	2	--	us2k¹		0	--	--	--	--
rs76698795^1,2	F,	--	55012143(+)	`CTGCAG/AAGGGA`	2	--	us2k¹		1		EA	120
rs79959883^1,2	F,	--	55012145(+)	`GCAGAG/AGGAGG`	2	--	us2k¹		1		WA	118
rs143965678^1,2		--	55012199(+)	`CCATAA/CGATGA`	2	--	us2k¹		0	--	--	--	--
rs187660165^1,2		--	55012226(+)	`GCTGAC/TTTCCT`	2	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ACOT11 (55007930 - 55104865 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 14 variations for ACOT11
9 CNVs: 97355 68699 6827 38995 58394 48338 84254 43778 63788
5 Indels: 84255 74490 84256 74489 84257

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ACOT11 for disorders           About GeneDecksing

OMIM gene information: 606803    OMIM disorders: --

4 diseases for ACOT11:    About MalaCards

obesity tinea unguium obesity, resistance to strabismus

Human Genome Epidemiology (HuGE) Navigator: ACOT11 (4 documents)

Export disorders for ACOT11 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ACOT11 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with ACOT11)

Utopia: connect your pdf to the dynamic
world of online information

BFIT, a unique acyl-CoA thioesterase induced in thermogenic brown adipose tissue: cloning, organization of the human gene and assessment of a potential link to obesity. (PubMed id 11696000)^{1, 2, 3, 9} Adams S.H.... Lewin D.A. (2001)
A revised nomenclature for mammalian acyl-CoA thioesterases/hydrolases. (PubMed id 16103133)^{1, 3} Hunt M.C....Alexson S.E. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)^{1, 2} Ishikawa K.... Ohara O. (1998)
Human brown fat inducible thioesterase variant 2 cellu lar localization and catalytic function. (PubMed id 22897136)¹ Chen D....Dunaway-Mariano D. (2012)
Comparative structural analysis of lipid binding START domains. (PubMed id 21738568)² Thorsell A.G.... Lehtio L. (2011)
Functional and structural properties of mammalian acy l-coenzyme A thioesterases. (PubMed id 20470824)¹ Kirkby B....Forwood J.K. (2010)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 26027	HGNC: 18156	AceView: THEA	Ensembl:ENSG00000162390	euGenes: HUgn26027
ECgene: ACOT11	H-InvDB: ACOT11

(According to HUGE)
About This Section

HUGE: KIAA0707

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ACOT11	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ACOT11 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for ACOT11 gene:
Search GeneIP for patents involving ACOT11

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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acyl-CoA thioesterase 11

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acyl-CoA thioesterase 11

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