Aliases for ACOT1 Gene
External Ids for ACOT1 Gene
Previous GeneCards Identifiers for ACOT1 Gene
GeneCards Summary for ACOT1 Gene
ACOT1 (Acyl-CoA Thioesterase 1) is a Protein Coding gene. Diseases associated with ACOT1 include Retinitis Pigmentosa 67 and Spindle Cell Hemangioma. Among its related pathways are oleate biosynthesis and Fatty acid elongation. GO annotations related to this gene include hydrolase activity and palmitoyl-CoA hydrolase activity. An important paralog of this gene is ACOT2.
UniProtKB/Swiss-Prot for ACOT1 Gene
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (By similarity).