V3 here soon-try beta now
Gene Search (GeneCards Home) | GeneCards Guide | User Feedback | Terms of Use | Notice about third-party sites
 

ACO2 Gene

protein-coding   GIFtS: 62

GC22P040189
aconitase 2, mitochondrial
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    
(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

Aliases
ACONM 1, 2
Aconitase 3
EC 4.2.1.3 3
MGC20605 2
MGC33908 2
OTTHUMP00000042146 2
OTTHUMP00000165920 2
Descriptions
Citrate hydro-lyase 2, 3
aconitase 2, mitochondrial 2
aconitate hydratase 2
External Ids
HGNC: 1181
Entrez Gene: 502
UniProtKB: Q997983
Ensembl: ENSG000001004127
Search outside databases for aliases for ACO2 gene

Previous GC identifers: GC22P038479 GC22P040108

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ACO2:
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme
that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step
of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It
was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the
serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by
RefSeq]

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ACO2 gene  

Entrez Gene cytogenetic band: 22q11.2-q13.31|22q13.2|22q13.2-q13.31   Ensembl cytogenetic band:  22q13.2   HGNC cytogenetic band: 22q13.2

ACO2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P040189:     (about GC identifiers)

Start:
40,195,075 bp from pter
End:
40,254,939 bp from pter
Size:
59,865 bases
Orientation:
plus strand
RefSeq DNA sequence:
NC_000022.9  NT_011520.11  
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ACON_HUMAN, Q99798 (See protein sequence)
Recommended Name: Aconitate hydratase, mitochondrial precursor  
Size: 780 amino acids; 85425 Da
Cofactor: Binds 1 4Fe-4S cluster per subunit. Binding of a 3Fe-4S cluster leads to an inactive
enzyme (By similarity)
Subunit: Monomer (By similarity)
Subcellular location: Mitochondrion (By similarity)
Secondary accessions: O75809 Q5JZ41 Q6FHX0 Q8TAQ6

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2


  • REFSEQ proteins: NP_001089.1  

    ENSEMBL proteins: 
    ENSP00000379769 ENSP00000216254 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Aconitase, Aconitase 2)
    Human Recombinant Proteins from Abnova (ACO2)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IDA18029348
    GO:0005739 mitochondrion TAS9630632
    GO:0005759 mitochondrial matrix EXP1946331
    About this table

    Antibodies for ACO2: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for ACO2
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (Aconitase, Aconitase 2), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (ACO2)
    Novus Biologicals Antibody for ACO2

    Assays for ACO2: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    5/8 InterPro domains/families (see all 8 ):
     IPR001030 Acoase/IPM_deHydtase_lsu_aba
     IPR018136 Aconitase_4Fe-4S_BS
     IPR000573 AconitaseA/IPMdHydase_ssu_swvl
     IPR015932 Aconitase/IPMdHydase_lsu_aba_2
     IPR006248 Aconitase_mito-like


       GeneDecks  ACO2 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q99798

    ProtoNet protein and cluster: Q99798

    2 Blocks protein families:
    IPB000573 Aconitate hydratase
    IPB001030 Aconitate hydratase


    UniProtKB/Swiss-Prot: ACON_HUMAN, Q99798
    Similarity: Belongs to the aconitase/IPM isomerase family

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ACO2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ACO2)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001098

                  Applied Biosystems Silencer® siRNAs for ACO2

                  Sigma-Aldrich siRNA for ACO2  
                         Sigma-Aldrich shRNA for ACO2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for ACO2
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_001098
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_001098
                                     untagged cDNA clone in CMV expression vector: NM_001098 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_001098

    UniProtKB/Swiss-Prot: ACON_HUMAN, Q99798
    Catalytic activity: Citrate = isocitrate
    Enzyme Number (IUBMB): EC 4.2.1.3 

    Genatlas biochemistry entry for ACO2:
    aconitase 2,iron sulfur protein,catalyzing the mitochondrial,second step of citric acid
    cycle,ubiquitously expressed,including multiple isoforms
    1 MGI phenotypic allele for Aco2 (no phenotypes)

    5 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003994 aconitate hydratase activity IEA--
    GO:0005506 iron ion binding IDA9630632
    GO:0016829 lyase activity IEA--
    GO:0046872 metal ion binding IEA--
    GO:0051539 4 iron, 4 sulfur cluster binding IEA--
    About this table

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section

    1 Invitrogen iPath™ Online BioAtlas - Pathway for ACO2 (Maps provided by GeneGo):
     Citric acid cycle (citrate cycle

       GeneDecks  ACO2 for the pathways selected above  
    About GeneDecksing

    2 Sigma-Aldrich "Your Favorite Gene" Pathways for  ACO2  (Your Favorite Gene powered by Ingenuity) 
     Glyoxylate and Dicarboxylate Metabolism
     Citrate Cycle

       GeneDecks  ACO2 for the pathways selected above  
    About GeneDecksing

    3 Kegg Pathways  (Kegg details for ACO2):
     hsa00020 Citrate cycle (TCA cycle)
     hsa00630 Glyoxylate and dicarboxylate metabolism
     hsa00720 Reductive carboxylate cycle (CO2 fixation)

       GeneDecks  ACO2 for the pathways selected above  
    About GeneDecksing
    UniProtKB/Swiss-Prot: ACON_HUMAN, Q99798
    Pathway: Carbohydrate metabolism; tricarboxylic acid cycle


    5/36 Interacting proteins for ACO2 (Q997982 ENSP000002162543) via UniProtKB, MINT, and/or STRING (see all 36 )

    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSENSP000003420563STRING (score=.99)
    IDH2ENSP000003318973STRING (score=.984)
    IDH3AENSP000002995183STRING (score=.981)
    IDH1ENSP000002609853STRING (score=.964)
    FXNENSP000003664823STRING (score=.958)
    About this table

    4 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006091 generation of precursor metabolites and energy TAS9630632
    GO:0006099 tricarboxylic acid cycle IDA9630632
    GO:0006101 citrate metabolic process IDA9630632
    GO:0008152 metabolic process IEA--
    About this table
    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Browse Small Molecules at Sigma-Aldrich

    Browse Tocris compounds for ACO2
    1 Novoseek chemical compound relationship for ACO2 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    pyruvate 33.81 1 11681208 (1)
    About this table


    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section

    Inhib.
    RNA:
    Invitrogen RNAi Products for gene knock-down (ACO2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ACO2)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001098

                  Sigma-Aldrich siRNA for ACO2  
                         Sigma-Aldrich shRNA for ACO2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001098  

    REFSEQ mRNAs for ACO2 gene: 

    NM_001098.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001098  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_001098
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_001098
                                     untagged cDNA clone in CMV expression vector: NM_001098 

    Additional cDNA sequence: 

    AK293562.1 AK296260.1 AK297213.1 AK301321.1 AK302691.1 AK314845.1 BC014092.2 BC026196.2 
    BC127658.1 BC127659.1 CR456365.1 CR536568.1 CR592345.1 CR595461.1 CR596181.1 CR596278.1 
    CR596641.1 CR613743.1 CR619036.1 CR621307.1 U80040.1 

    24/46 DOTS entries (see all 46 ):

    DT.97820748  DT.420057  DT.100891526  DT.95195997  DT.100891551  DT.100758261  DT.100891513  DT.100891519 
    DT.100891524  DT.100891528  DT.40114844  DT.75125607  DT.95302501  DT.100759825  DT.100891509  DT.100891539 
    DT.100891546  DT.100891547  DT.420055  DT.87078063  DT.92457677  DT.92457691  DT.97855757  DT.100026962 

    24/889 AceView cDNA sequences (see all 889 ):

    BQ775995 BU181891 BX342748 BU501912 BF724140 AA437114 BM795120 BF026635 
    Z98458 CR614581 BM471282 BQ894362 BI869319 BE782540 AI471244 AI972921 
    BG032395 BU177463 BQ642766 CR613743 BM849867 BU584457 BM017912 BQ006733 

    highest scoring ESTs for ACO2:

    AA054733 AA054740 AA065109 AA084544 AA101510 AA114832 AA114955 AA290633 AA291040 AA324903 

    Unigene Cluster for ACO2:

    Aconitase 2, mitochondrial
    Hs.643610  [show with all ESTs]
    Unigene Representative Sequence: CR595461


    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ACO2 (see all 6 )

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11
    SP1:                    -                                   -     -                                             
    SP2:                    -                                                                                       
    SP3:                                                        -     -                                             
    SP4:                                                                                                            
    SP5:                    -                 -     -     -     -     -     -     -     -     -     -     -         

    About this scheme

    ECgene alternative splicing isoforms for ACO2

    2 Ensembl transcripts including schematic representations:
    ENST00000396512  ENST00000216254  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ACO2 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ACO2

    1 / 2 / 3

    4 probe-sets matching ACO2 gene


    Affymetrix
    probe-set
    Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    160044_g_at2, 3 U95-A 2 1.00 0.94 0.97 0.95 NM_001098 0.80 1.00 0.91 1
    89636_f_at2, 3 U95-E 2 0.94 0.67 0.98 1.06 AW006214 0.60 0.83 0.73 1

    200793_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_001098 0.80 1.00 0.91 1

    200793_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    GeneDecks  ACO2 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene cluster: Hs.643610

    Expression variation in blood from EXPOLDB for ACO2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section


    Orthologs for ACO2 gene from 5/21 species (see all 21 )
    Organism Gene Locus Description Human
    Similarity
    NCBI accessions
    dog
    (Canis familiaris)
    ACO21   -- aconitase 2, mitochondrial 91.45(n)
    96.54(a)
    474487  XM_853210.1  XP_858303.1 
    chimpanzee
    (Pan troglodytes)
    ACO21   -- aconitase 2, mitochondrial 90.97(n)
    83.23(a)
    470193  XM_001141262.1  XP_001141262.1 
    cow
    (Bos taurus)
    ACO21   -- aconitase 2, mitochondrial 91.37(n)
    96.41(a)
    280976  NM_173977.2  NP_776402.1 
    rat
    (Rattus norvegicus)
    Aco21   -- aconitase 2, mitochondrial 89.74(n)
    96.41(a)
    79250  NM_024398.2  NP_077374.2 
    mouse
    (Mus musculus)
    Aco21, 5 155
    aconitase 2, mitochondrial1, 5 89.87(n)1
    96.79(a)1
    114291  NM_080633.21  NP_542364.11 
     AA0345535  AA4101235  (see all 47)
    About this table        Species with no ortholog for ACO2

    ENSEMBL Gene Tree for ACO2
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for ACO2 gene
    IREB22  ACO12  

    Pseudogenes
    3 related pseudogenes


    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/232 NCBI SNPs in ACO2 are shown (see all 232 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 94)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 22 posSequenceRecsAA
    Chg
    TypeMoreRecsAllele
    freq
    PopTotal
    sample
    More
    ------------
    rs1378311,2
    A,C,F,H,O40233759(+) CTGACA/CCTCTC 1 T/T syn1 ese310Minor allele frequency- C:0.41EA NA EU WA 2244
    rs17999321,2
    A,C,F,H40241471(+) GGGAGC/TTGAAG 1 L/L syn1 ese310Minor allele frequency- T:0.33EA EU WA NA 2450
    rs19601821,2
    A,C,F,H,O40248558(+) TGGCCA/GATGGC 1 -- int113Minor allele frequency- G:0.15MN EU EA WA NA 1332
    rs2033201,2
    A,C,F,H,O40243423(-) CCCACA/GCACCT 1 -- int111Minor allele frequency- G:0.37EA NA EU 2084
    rs1693611,2
    A,C,F,H,O40207935(-) TGGGAC/TTACTA 1 -- int111Minor allele frequency- T:0.08EU EA WA NA 922
    rs22840801,2
    A,C,F,H,O40217271(+) CAGAAG/CGGGTT 1 -- int18Minor allele frequency- C:0.36EA EU WA NA 1848
    rs22674341,2
    C,F,H,O40208541(+) TATAAC/TGATGC 1 -- int19Minor allele frequency- T:0.31EA EU WA NA 2224
    rs22674351,2
    A,C,F,H40213740(+) GTCCAA/GTGTCC 1 -- int18Minor allele frequency- G:0.24EU EA WA 836
    rs60023901,2
    A,C,F,H40199571(+) TTACGT/CAGAAA 1 -- int14Minor allele frequency- C:0.07EU EA WA 418
    rs2033191,2
    A,C,F,H40244539(-) ACCCAG/ATTAAT 1 -- int115Minor allele frequency- A:0.42EU EA WA NA 1340
    About this table

    HapMap Linkage Disequilibrium images for ACO2 (up to first 250kb)

    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    OMIM: 100850

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      --

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    10/39 PubMed articles for ACO2 gene (see all 39 ):
    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section

    Entrez Gene: 50 HGNC: 118 AceView: ACO2 Ensembl:ENSG00000100412 euGenes: HUgn50
    ECgene: ACO2 H-InvDB: ACO2
    (According to HUGE)
    About This Section

      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    NameDescription
    Wikipedia http://en.wikipedia.org/wiki/Aconitase
    (Available from WIS Yeda, Salk, Tufts)
    About This Section

      --
    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ACO2:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
      Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ACO2-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for ACO2 Antibodies for ACO2
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for ACO2 Browse small molecules at Sigma-Aldrich
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
     Flow Cytometry Kits   Protease Activity Assays & Reagents  
     Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
     Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
     Recombinant & Natural Proteins  

     Recombinant Proteins (ACO2)
     Antibodies (ACO2)
     Chimera RNAi (ACO2)
     Custom Service for Mouse Mab
     Custom Service for Rabbit Pab from Full-length Protein
      
     Search for Antibodies & Assays

     Recombinant Proteins
    (Aconitase, Aconitase 2)
     Antibodies (Aconitase, Aconitase 2)
     Search OriGene for ACO2
     Search Tocris compounds for ACO2




     Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
     Antibodies for ACO2

    GeneCards Homepage    -    Last full update: 1 Jul 2009        Incremental update: 13 Oct 2009

    Random Gene From GIFtS : about GIFtS

    Gene Index:   3   5   A   B   C   D   E   F   G   H   I   J   K   L   M   N   O   P   Q   R   S   T   U   V   W   X   Y   Z

    Developed at the Crown Human Genome Center & Weizmann Institute of Science



    The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
    ACO2 Gene at Home site.
    Version 2.41.1
    server5.xennexinc.com