V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

ACO2 Gene

protein-coding GIFtS: 62

GC22P040189

aconitase 2, mitochondrial
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
ACONM ^¹, ²
Aconitase ^³
EC 4.2.1.3 ^³
MGC20605 ^²
MGC33908 ^²
OTTHUMP00000042146 ^²
OTTHUMP00000165920 ^²

Descriptions
Citrate hydro-lyase ^², ³
aconitase 2, mitochondrial ^²
aconitate hydratase ^²

External Ids
HGNC: 118¹
Entrez Gene: 50²
UniProtKB: Q99798³
Ensembl: ENSG00000100412⁷

Search outside databases for aliases for ACO2 gene

Previous GC identifers: GC22P038479 GC22P040108

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ACO2:

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme

that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step

of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It

was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the

serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by

RefSeq]

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ACO2 gene

Entrez Gene cytogenetic band: 22q11.2-q13.31|22q13.2|22q13.2-q13.31 Ensembl cytogenetic band: 22q13.2 HGNC cytogenetic band: 22q13.2

ACO2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22P040189: (about GC identifiers)

Start:	40,195,075 bp from pter
End:	40,254,939 bp from pter
Size:	59,865 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000022.9 NT_011520.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ACON_HUMAN, Q99798 (See protein sequence)

Recommended Name: Aconitate hydratase, mitochondrial precursor

Size: 780 amino acids; 85425 Da

Cofactor: Binds 1 4Fe-4S cluster per subunit. Binding of a 3Fe-4S cluster leads to an inactive

enzyme (By similarity)

Subunit: Monomer (By similarity)

Subcellular location: Mitochondrion (By similarity)

Secondary accessions: O75809 Q5JZ41 Q6FHX0 Q8TAQ6

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_001089.1

ENSEMBL proteins:

ENSP00000379769 ENSP00000216254

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Aconitase, Aconitase 2)
	Human Recombinant Proteins from Abnova (ACO2)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	18029348
GO:0005739	mitochondrion	TAS	9630632
GO:0005759	mitochondrial matrix	EXP	1946331

About this table

Antibodies for ACO2:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ACO2
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Aconitase, Aconitase 2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ACO2)
	Novus Biologicals Antibody for ACO2

Assays for ACO2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q99798

ProtoNet protein and cluster: Q99798

2 Blocks protein families:

IPB000573 Aconitate hydratase

IPB001030 Aconitate hydratase

UniProtKB/Swiss-Prot: ACON_HUMAN, Q99798

Similarity: Belongs to the aconitase/IPM isomerase family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ACO2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ACO2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001098

Applied Biosystems Silencer® siRNAs for ACO2

Sigma-Aldrich siRNA for ACO2

Sigma-Aldrich shRNA for ACO2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for ACO2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001098
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001098
untagged cDNA clone in CMV expression vector: NM_001098

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001098

UniProtKB/Swiss-Prot: ACON_HUMAN, Q99798

Catalytic activity: Citrate = isocitrate

Enzyme Number (IUBMB): EC 4.2.1.3

Genatlas biochemistry entry for ACO2:

aconitase 2,iron sulfur protein,catalyzing the mitochondrial,second step of citric acid

cycle,ubiquitously expressed,including multiple isoforms

1 MGI phenotypic allele

for Aco2 (no phenotypes)

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003994	aconitate hydratase activity	IEA	--
GO:0005506	iron ion binding	IDA	9630632
GO:0016829	lyase activity	IEA	--
GO:0046872	metal ion binding	IEA	--
GO:0051539	4 iron, 4 sulfur cluster binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for ACO2 (Your Favorite Gene powered by Ingenuity)

Glyoxylate and Dicarboxylate Metabolism
Citrate Cycle

GeneDecks ACO2 for the pathways selected above

About GeneDecksing

UniProtKB/Swiss-Prot: ACON_HUMAN, Q99798

Pathway: Carbohydrate metabolism; tricarboxylic acid cycle

5/36 Interacting proteins for ACO2 (Q99798² ENSP00000216254³) via UniProtKB, MINT, and/or STRING (see all 36 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CS	ENSP00000342056³	STRING (score=.99)
IDH2	ENSP00000331897³	STRING (score=.984)
IDH3A	ENSP00000299518³	STRING (score=.981)
IDH1	ENSP00000260985³	STRING (score=.964)
FXN	ENSP00000366482³	STRING (score=.958)

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006091	generation of precursor metabolites and energy	TAS	9630632
GO:0006099	tricarboxylic acid cycle	IDA	9630632
GO:0006101	citrate metabolic process	IDA	9630632
GO:0008152	metabolic process	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ACO2
1 Novoseek chemical compound relationship for ACO2 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
pyruvate	33.81	1	11681208 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ACO2)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ACO2)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001098

Sigma-Aldrich siRNA for ACO2

Sigma-Aldrich shRNA for ACO2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001098

REFSEQ mRNAs for ACO2 gene:

NM_001098.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001098

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001098
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001098
                                 untagged cDNA clone in CMV expression vector: NM_001098

Additional cDNA sequence:

AK293562.1 AK296260.1 AK297213.1 AK301321.1 AK302691.1 AK314845.1 BC014092.2 BC026196.2

BC127658.1 BC127659.1 CR456365.1 CR536568.1 CR592345.1 CR595461.1 CR596181.1 CR596278.1

CR596641.1 CR613743.1 CR619036.1 CR621307.1 U80040.1

24/46 DOTS entries (see all 46 ):

DT.97820748 DT.420057 DT.100891526 DT.95195997 DT.100891551 DT.100758261 DT.100891513 DT.100891519

DT.100891524 DT.100891528 DT.40114844 DT.75125607 DT.95302501 DT.100759825 DT.100891509 DT.100891539

DT.100891546 DT.100891547 DT.420055 DT.87078063 DT.92457677 DT.92457691 DT.97855757 DT.100026962

24/889 AceView cDNA sequences (see all 889 ):

BQ775995 BU181891 BX342748 BU501912 BF724140 AA437114 BM795120 BF026635

Z98458 CR614581 BM471282 BQ894362 BI869319 BE782540 AI471244 AI972921

BG032395 BU177463 BQ642766 CR613743 BM849867 BU584457 BM017912 BQ006733

highest scoring ESTs for ACO2:

AA054733 AA054740 AA065109 AA084544 AA101510 AA114832 AA114955 AA290633 AA291040 AA324903

Unigene Cluster for ACO2:

Aconitase 2, mitochondrial

Hs.643610 [show with all ESTs]

Unigene Representative Sequence: CR595461

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ACO2 (see all 6 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3	^	4	^	5	^	6a	·	6b	·	6c	^	7a	·	7b	^	8a	·	8b	^	9	^	10	^	11
SP1:							-												-		-
SP2:							-
SP3:																			-		-
SP4:
SP5:							-						-		-		-		-		-		-		-		-		-		-		-

About this scheme

ECgene alternative splicing isoforms for ACO2

2 Ensembl transcripts including schematic representations:

ENST00000396512 ENST00000216254

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ACO2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ACO2

¹ / ² / ³

4 probe-sets matching ACO2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
160044_g_at²^{, 3}	U95-A	2	1.00	0.94	0.97	0.95	NM_001098	0.80	1.00	0.91	1
89636_f_at²^{, 3}	U95-E	2	0.94	0.67	0.98	1.06	AW006214	0.60	0.83	0.73	1
200793_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001098	0.80	1.00	0.91	1
200793_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks ACO2 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.643610
Expression variation in blood from EXPOLDB for ACO2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ACO2 gene from 5/21 species (see all 21 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ACO2¹	--	aconitase 2, mitochondrial	91.45(n) 96.54(a)	474487 XM_853210.1 XP_858303.1
chimpanzee (Pan troglodytes)	ACO2¹	--	aconitase 2, mitochondrial	90.97(n) 83.23(a)	470193 XM_001141262.1 XP_001141262.1
cow (Bos taurus)	ACO2¹	--	aconitase 2, mitochondrial	91.37(n) 96.41(a)	280976 NM_173977.2 NP_776402.1
rat (Rattus norvegicus)	Aco2¹	--	aconitase 2, mitochondrial	89.74(n) 96.41(a)	79250 NM_024398.2 NP_077374.2
mouse (Mus musculus)	Aco2^{1, 5}	15⁵	aconitase 2, mitochondrial^{1, 5}	89.87(n)¹ 96.79(a)¹	11429¹ NM_080633.2¹ NP_542364.1¹ AA034553⁵ AA410123⁵ (see all 47)

About this table Species with no ortholog for ACO2

ENSEMBL Gene Tree for ACO2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for ACO2 gene

IREB2² ACO1²

Pseudogenes

3 related pseudogenes

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/232 NCBI SNPs in ACO2 are shown (see all 232 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 94)

AB	SNP ID	Valid	Chr 22 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs137831^1,2	A,C,F,H,O	40233759(+)	`CTGACA/CCTCTC`	1	T/T	syn¹ ese³		10	EA NA EU WA	2244
	rs1799932^1,2	A,C,F,H	40241471(+)	`GGGAGC/TTGAAG`	1	L/L	syn¹ ese³		10	EA EU WA NA	2450
	rs1960182^1,2	A,C,F,H,O	40248558(+)	`TGGCCA/GATGGC`	1	--	int¹		13	MN EU EA WA NA	1332
	rs203320^1,2	A,C,F,H,O	40243423(-)	`CCCACA/GCACCT`	1	--	int¹		11	EA NA EU	2084
	rs169361^1,2	A,C,F,H,O	40207935(-)	`TGGGAC/TTACTA`	1	--	int¹		11	EU EA WA NA	922
	rs2284080^1,2	A,C,F,H,O	40217271(+)	`CAGAAG/CGGGTT`	1	--	int¹		8	EA EU WA NA	1848
	rs2267434^1,2	C,F,H,O	40208541(+)	`TATAAC/TGATGC`	1	--	int¹		9	EA EU WA NA	2224
	rs2267435^1,2	A,C,F,H	40213740(+)	`GTCCAA/GTGTCC`	1	--	int¹		8	EU EA WA	836
	rs6002390^1,2	A,C,F,H	40199571(+)	`TTACGT/CAGAAA`	1	--	int¹		4	EU EA WA	418
	rs203319^1,2	A,C,F,H	40244539(-)	`ACCCAG/ATTAAT`	1	--	int¹		15	EU EA WA NA	1340

About this table

HapMap Linkage Disequilibrium images for ACO2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 100850

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/39 PubMed articles for ACO2 gene (see all 39 ):

The DNA sequence of human chromosome 22. (PubMed id 10591208)^{2, 3, 4} Dunham I....O'Brien K.P. (1999)
Characterization of the human mitochondrial aconitase gene (ACO2). (PubMed id 9630632)^{1, 3, 4} Mirel D.B....Wilhelmsen K.C. (1998)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)^{3, 4} Collins J.E.... Dunham I. (2004)
Purification and partial amino acid sequence of human aconitase. (PubMed id 1946331)^{3, 4} Baldwin G.S.... Simpson R. (1991)
Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia. (PubMed id 19110265)³ Martins-de-Souza D....Dias-Neto E. (2008)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)³ Barbe L....Andersson-Svahn H. (2008)
Manganese antagonizes iron blocking mitochondrial aconitase expression in human prostate carcinoma cells. (PubMed id 16625280)³ Tsui K.H....Juang H.H. (2006)
Characterization of the mitochondrial aconitase promoter and the identification of transcription factor binding. (PubMed id 16598741)³ Yu Z....Franklin R.B. (2006)
The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)⁴ Sjoeblom T.... Velculescu V.E. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 50	HGNC: 118	AceView: ACO2	Ensembl:ENSG00000100412	euGenes: HUgn50
ECgene: ACO2	H-InvDB: ACO2

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
Wikipedia	http://en.wikipedia.org/wiki/Aconitase

Licensable Technologies for ACO2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for ACO2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ACO2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ACO2		Antibodies for ACO2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ACO2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (ACO2)
	Antibodies (ACO2)
	Chimera RNAi (ACO2)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (Aconitase, Aconitase 2)
	Antibodies (Aconitase, Aconitase 2)

Search OriGene for ACO2

Search Tocris compounds for ACO2

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ACO2

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
ACO2 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

ACO2 Gene

protein-coding GIFtS: 62

Aliases &
Descriptions
for ACO2

Summaries
for ACO2

Genomic Location
for ACO2

Proteins
for ACO2

Protein Domains/
Families
for ACO2

Gene Function
for ACO2

Pathways & Interactions
for ACO2

Drugs & Compounds
for ACO2

Transcripts
for ACO2

Expression
for ACO2

Orthologs
for ACO2

Paralogs
for ACO2

SNPs/Variants
for ACO2

Disorders & Mutations
for ACO2

Medical News
for ACO2

Publications
for ACO2

Search for ACO2

Genome Databases showing ACO2

Other Databases showing ACO2

Specialized Databases showing ACO2

Licensable Technologies
for ACO2

Services
for ACO2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ACO2 Gene

protein-coding GIFtS: 62

Aliases & Descriptionsfor ACO2

Summariesfor ACO2

Genomic Locationfor ACO2

Proteinsfor ACO2

Protein Domains/Familiesfor ACO2

Gene Functionfor ACO2

Pathways & Interactionsfor ACO2

Drugs & Compoundsfor ACO2

Transcriptsfor ACO2

Expression for ACO2

Orthologsfor ACO2

Paralogsfor ACO2

SNPs/Variantsfor ACO2

Disorders & Mutationsfor ACO2

Medical Newsfor ACO2

Publicationsfor ACO2

Search for ACO2

Genome Databases showing ACO2

Other Databases showing ACO2

Specialized Databases showing ACO2

Licensable Technologiesfor ACO2

Servicesfor ACO2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ACO2

Summaries
for ACO2

Genomic Location
for ACO2

Proteins
for ACO2

Protein Domains/
Families
for ACO2

Gene Function
for ACO2

Pathways & Interactions
for ACO2

Drugs & Compounds
for ACO2

Transcripts
for ACO2

Expression
for ACO2

Orthologs
for ACO2

Paralogs
for ACO2

SNPs/Variants
for ACO2

Disorders & Mutations
for ACO2

Medical News
for ACO2

Publications
for ACO2

Licensable Technologies
for ACO2

Services
for ACO2