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ACIN1 Gene

protein-coding   GIFtS: 56

GC14M023527
apoptotic chromatin condensation inducer 1
(Previous name: apoptotic chromatin condensation inducer in the nucleus )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: ACINUS)
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Aliases &
Descriptions
for ACIN1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section

  User Feedback
Aliases & Descriptions
apoptotic chromatin condensation inducer 11 2     ACN2
KIAA06701 2 3     DKFZp667N1072
apoptotic chromatin condensation inducer in the nucleus1 2     functional spliceosome-associated protein 1522
fSAP1521 2     Acinus3
ACINUS2 3     

External Ids:    HGNC: 170661   Entrez Gene: 229852   Ensembl: ENSG000001008137   UniProtKB: Q9UKV33   

Search outside databases for aliases for ACIN1 gene

Previous GC identifers: GC14M021518 GC14M022597

Summaries
for ACIN1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

  User Feedback		 UniProtKB/Swiss-Prot: ACINU_HUMAN, Q9UKV3
Function: Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on
mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and
cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent
mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3

Gene Wiki entry for ACIN1

Genomic Views
for ACIN1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC and Ensembl (release 56), Regulatory elements and Epigenetics data according to SABiosciences)
About This Section

  User Feedback		 Regulatory elements:
"" SABiosciences Regulatory transcription factor binding sites in the ACIN1 gene upstream (promoter) region "":
AP-1   c-Fos   c-Jun   SRF   CUTL1   Elk-1   STAT1   AhR   YY1   ATF-2   

Epigenetics:
"" SABiosciences Methyl-Profiler DNA Methylation qPCR Primer Assays for ACIN1:  ""
MePH28392-1A   MePH18101-1A   

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q11.2   Ensembl cytogenetic band:  14q11.2   HGNC cytogenetic band: 14q11.2

ACIN1 Gene in genomic location: bands according to Ensembl, locations according to "" (and/or Entrez Gene and/or Ensembl if different)
""

GeneLoc gene densities for chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M023527:  view genomic region     (about GC identifiers)

Start:
 23,527,773 bp from pter
End:
 23,564,823 bp from pter
Size:
 37,051 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000014.8  NT_026437.12  

Proteins
for ACIN1 gene

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene, Novus Biologicals, and/or Sino Biological,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 May 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abnova, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

  User Feedback		 UniProtKB/Swiss-Prot: ACINU_HUMAN, Q9UKV3 (See protein sequence)
Recommended Name: Apoptotic chromatin condensation inducer in the nucleus  
Size: 1341 amino acids; 151888 Da
Subunit: Found in a mRNA splicing-dependent exon junction complex (EJC), at least composed of ACIN1, CASC3, EIF4A3,
MAGOH, PNN, RBM8A, RNPS1, SAP18 and THOC4. Forms heterodimers with RNPS1. Found in a heterotrimeric complex with
ACIN1, RNPS1 and SAP18. Interacts with API5
Subcellular location: Nucleus
Secondary accessions: O75158 Q9UG91 Q9UKV1 Q9UKV2
Alternative splicing: 3 isoforms:  Q9UKV3-1   Q9UKV3-2   Q9UKV3-3   

Post-translational modifications:

  • Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (5 alternative transcripts): 
    NP_001158286.1  NP_001158287.1  NP_001158288.1  NP_001158289.1  NP_055792.1  


    ENSEMBL proteins: 
    ENSP00000405677 ENSP00000350073 ENSP00000380502 ENSP00000345541 ENSP00000262710 


    Human Recombinant Proteins 
    ""Browse Purified and Recombinant Proteins at Millipore
    ""Browse Human Recombinant Proteins at Sigma-Aldrich
    "" Browse R&D Systems for human recombinant proteins
    ""Browse recombinant and purified proteins available from Enzo Life Sciences
    ""HuPro® and/or Recombinant Proteins from Abnova for ACIN1 ""
    ""Browse Origene full length recombinant human proteins expressed in human HEK293 cells
    ""Novus Biologicals Protein for ACIN1  ""
    ""Browse Sino Biological Recombinant Proteins  ""

    4 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IDA10490026 18029348
    GO:0005730NOT nucleolus IDA18029348
    GO:0005737 cytoplasm IDA18029348
    GO:0005829 cytosol EXP10490026
    About this table

    "" ACIN1 for ontologies           About GeneDecksing



    Antibodies for ACIN1: 
    ""Millipore Mono- and Polyclonal Antibodies for the study of ACIN1
    ""Sigma-Aldrich Antibodies for ACIN1
    "" Browse R&D Systems for Antibodies
    ""Cell Signaling Technology (CST) Antibodies for ACIN1  (Acinus)
    ""Monoclonal and Polyclonal Antibodies from Abnova (ACIN1)
    ""Browse Origene Antibodies ""
    ""Novus Biologicals Antibodies for ACIN1
    ""Browse antibodies at Epitomics

    Assays for ACIN1: 
    ""Browse Kits and Assays available from Millipore
    ""Browse ELISAs at Sigma-Aldrich
    "" Browse R&D Systems for biochemical assays
    ""Browse Enzo Life Sciences for kits & assays

    Protein Domains/
    Families
    for ACIN1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

      User Feedback
    "" ACIN1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR012677 a_b_plait_nuc_bd
     IPR003034 SAP_DNA_bd
     IPR000504 RRM_RNP1

    Graphical View of Domain Structure for InterPro Entry Q9UKV3

    ProtoNet protein and cluster: Q9UKV3

    1 Blocks protein family: IPB003034 DNA-binding SAP

    UniProtKB/Swiss-Prot: ACINU_HUMAN, Q9UKV3
    Similarity: Contains 1 SAP domain

    Gene Function
    for ACIN1 gene

    (According to MGI May 08 2010, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, Abnova, siRNAs from Applied Biosystems, Sigma-Aldrich, Clones from Millipore, Sigma-Aldrich, OriGene, Sino Biological, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene.)
    About This Section

      User Feedback
    Inhib.
    RNA:    		""Browse for Gene Knock-down Tools from Millipore
    ""Abnova Chimera RNAi Products for Gene knock-down (ACIN1)
    "" Origene 29mer shRNA kits in GFP-retroviral vector (see all 5): ACIN1
    Origene shRNA RFP (see all 5): ACIN1
    Origene basic RS shRNA (see all 5): ACIN1

    ""Applied Biosystems Silencer® siRNAs for ACIN1
    ""Sigma-Aldrich siRNA for ACIN1
    Sigma-Aldrich shRNA for ACIN1
    Explore Sigma-Aldrich super-pooled esiRNAs
    Clones:""Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    ""Browse iPSC Reprogramming Factors at Sigma-Aldrich
    "" Origene GFP tagged cDNA clones in CMV expression vector (see all 5): ACIN1
    Origene Myc/DDK tagged cDNA clones in CMV expression vector (see all 5): ACIN1
    Origene untagged cDNA clones in CMV expression vector (see all 6): ACIN1
    ""Browse Sino Biological Human cDNA Clones  ""

    UniProtKB/Swiss-Prot: ACINU_HUMAN, Q9UKV3
    Function: Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on
    mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and
    cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent
    mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3

    4 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166 nucleotide binding IEA--
    GO:0003676 nucleic acid binding NAS10490026
    GO:0016887 ATPase activity NAS10490026
    GO:0019899 enzyme binding NAS10490026
    About this table

    "" ACIN1 for ontologies           About GeneDecksing

    Animal Models: 2 MGI phenotypic alleles "" for Acin1 (no phenotypes)


    "" ACIN1 for phenotypes           About GeneDecksing

    Pathways & Interactions
    for ACIN1 gene

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, Applied Biosystems GeneAssist, KEGG and/or UniProtKB, (map by GeneGo),
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene).
    About This Section

      User Feedback
    "" ACIN1 for pathways           About GeneDecksing

    2 "" Sigma-Aldrich "Your Favorite Gene" Pathways for  ACIN1  (Your Favorite Gene powered by Ingenuity)
      ""  Apoptosis Signaling
    Purine Metabolism

    1 "" Cell Signaling Technology (CST) Pathway for ACIN1: 
      ""  Death Receptor Signaling

    1 "" Kegg Pathway  (Kegg details for ACIN1):
      ""  hsa03040 Spliceosome

    "" Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ACIN1

    5/10 Interacting proteins for ACIN1 (Q9UKV32 ENSP000002627103) via UniProtKB, MINT, and/or STRING (see all 10 ) ""
    InteractantInteraction Details
    GeneCardExternal ID(s)
    API5Q9BZZ52MINT-7289283 MINT-7289297 MINT-7289318 MINT-7289249 MINT-7289353
    ABCF3Q9NUQ82MINT-65164
    AKR1C3P423302MINT-63742
    BTBD10Q9BSF82MINT-65328
    KLHL26Q53HC52MINT-65639
    About this table

    4 Gene Ontology (GO) biological process terms (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915 apoptosis IEA--
    GO:0030218 erythrocyte differentiation IEP11208865
    GO:0030263 apoptotic chromosome condensation IDA10490026
    GO:0045657 positive regulation of monocyte differentiation IEP12393560
    About this table

    "" ACIN1 for ontologies           About GeneDecksing


    Drugs & Compounds
    for ACIN1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

      User Feedback
    "" ACIN1 for compounds           About GeneDecksing

    "" Browse drugs & compounds from Enzo Life Sciences
    ""Browse Small Molecules at Sigma-Aldrich

    "" Browse Tocris compounds for ACIN1
    6 ""Novoseek chemical compound relationships for ACIN1 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    methylmercury hydroxide 3.20 1 16177823 (1)
    lupeol 2.56 1 16322271 (1)
    poly(adpribose) 1.51 1 16322271 (1)
    urea 0.75 1 2891351 (1)
    glutamine 0.71 1 2891351 (1)
    adenosine 0.45 1 156638 (1)
    About this table


    Transcripts
    for ACIN1 gene

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 223 Homo sapiens; Apr 2 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Primers from OriGene and/or SABiosciences,
    Expression Assays from Applied Biosystems)
    About This Section

      User Feedback
    Inhib.
    RNA:    		""Browse for Gene Knock-down Tools from Millipore
    ""Abnova Chimera RNAi Products for Gene knock-down (ACIN1)
    ""Applied Biosystems Silencer® siRNAs:  NM_001164814  NM_001164815  NM_001164816  NM_001164817  NM_014977  
    "" Origene 29mer shRNA kits in GFP-retroviral vector (see all 5): ACIN1
    Origene shRNA RFP (see all 5): ACIN1
    Origene basic RS shRNA (see all 5): ACIN1

    ""Sigma-Aldrich siRNA for ACIN1
    Sigma-Aldrich shRNA for ACIN1
    Explore Sigma-Aldrich super-pooled esiRNAs

    microRNA:""9 SABiosciences microRNAs that regulate ACIN1: ""
    hsa-miR-142-5p hsa-miR-519d hsa-miR-20a hsa-miR-224 hsa-miR-188-5p hsa-miR-106a hsa-miR-106b hsa-miR-20b hsa-miR-17
    Assays:  ""Applied Biosystems TaqMan® Gene Expression Assays:  
    NM_001164814  NM_001164815  NM_001164816  NM_001164817  NM_014977  


    Clones:"" Origene GFP tagged cDNA clones in CMV expression vector (see all 5): ACIN1
    Origene Myc/DDK tagged cDNA clones in CMV expression vector (see all 5): ACIN1
    Origene untagged cDNA clones in CMV expression vector (see all 6): ACIN1
    Primers:"" Origene genome-wide validated SYBR primer pairs: ACIN1
    ""SABiosciences RT2 qPCR Primer Assay for ACIN1: PPH14661A ""

    REFSEQ mRNAs for ACIN1 gene (5 alternative transcripts): 

    NM_001164814.1  NM_001164815.1  NM_001164816.1  NM_001164817.1  NM_014977.3  

    Additional cDNA sequence: 

    AB014570.2 AF124726.1 AF124727.1 AF124728.1 AK299034.1 AL050382.1 AL833228.1 BC032770.1 
    BC140805.1 BX247975.1 

    24/39 DOTS entries (see all 39 ):

    DT.100828728  DT.100703400  DT.100828733  DT.100828730  DT.441873  DT.99952589  DT.91757510  DT.91828716 
    DT.95178277  DT.120788380  DT.91716345  DT.101969332  DT.40213840  DT.91939335  DT.100807424  DT.120788322 
    DT.91640659  DT.120788320  DT.92068352  DT.100029093  DT.100828734  DT.91672008  DT.95256792  DT.95259771 

    24/360 AceView cDNA sequences (see all 360 ):

    AL041390 CA429041 F28348 R23237 BQ638786 AL050382 BG236141 AW771830 
    AF124727 BM979980 AA341173 BX247975 H80276 BQ951195 BU902235 AI049963 
    BM848419 AF124728 AL121100 AA047063 CA421729 CD244446 BU727824 BQ646643 

    "" highest scoring ESTs for ACIN1:

    AA046111 AA047063 AA047064 AA098828 AA098961 AA182785 AA191047 AA247392 AA250772 AA283206 

    Unigene Cluster for ACIN1:

    Apoptotic chromatin condensation inducer 1
    Hs.124490  [show with all ESTs]
    Unigene Representative Sequence: NM_014977


    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for ACIN1 (see all 7 )

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b · 13c ^ 14
    SP1:                                                                                                                              
    SP2:                                                                          -     -     -           -     -     -     -         
    SP3:                          -                                                                                                   
    SP4:                                                                          -           -           -     -                     
    SP5:                                                                                                                              

    About this scheme

    ECgene alternative splicing isoforms for ACIN1

    6 Ensembl transcripts including schematic representations:
    ENST00000457657  ENST00000357481  ENST00000397341  ENST00000338631  ENST00000473758  ENST00000262710  

    Expression
    for ACIN1 gene

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 223 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems, Primers from OriGene and/or SABiosciences )
    About This Section

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    ACIN1 expression in normal and diseased human tissues

    "" Applied Biosystems TaqMan ® Gene Expression Assays for ACIN1

    1""  / 2""  / 3""

    3 probe-sets matching ACIN1 gene

    Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    33398_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 AB014570 0.80 0.80 0.80 1
    201715_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_014977 0.40 0.67 0.55 1
    201715_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table

    "" ACIN1 for expression           About GeneDecksing

    Data from Genenote  (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: AAGTAAAGAA

    SOURCE GeneReport for Unigene cluster: Hs.124490

    Expression variation in blood from EXPOLDB for ACIN1

    UniProtKB/Swiss-Prot: ACINU_HUMAN, Q9UKV3
    Tissue specificity: Ubiquitous

    Primers:"" Origene genome-wide validated SYBR primer pairs: ACIN1 ""
    ""SABiosciences RT2 qPCR Primer Assay for ACIN1: PPH14661A ""

    Orthologs
    for ACIN1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI May 08 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section

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    Orthologs for ACIN1 gene from 5/11 species (see all 11 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 ACIN11   -- apoptotic chromatin condensation inducer 1 91.91(n)
    92.66(a)    		 480247  XM_853204.1  XP_858297.1 
    chimpanzee
    (Pan troglodytes)    		 ACIN11   -- apoptotic chromatin condensation inducer 1 99.59(n)
    99.54(a)    		 452792  XM_509847.2  XP_509847.2 
    cow
    (Bos taurus)    		 ACIN11   -- apoptotic chromatin condensation inducer 1 92.07(n)
    92.57(a)    		 534600  XM_614421.3  XP_614421.3 
    rat
    (Rattus norvegicus)    		 Acin11   -- apoptotic chromatin condensation inducer 1 87.52(n)
    87.49(a)    		 305884  XM_240178.4  XP_240178.3 
    mouse
    (Mus musculus)    		 Acin11, 5 145
    		 apoptotic chromatin condensation inducer 11, 5 86.7(n)1
    86.57(a)1    		 562151  NM_023190.11  NP_075679.11 
     AF1247255  AF1247295  (see all 30)
    About this table        Species with no ortholog for ACIN1

    ENSEMBL Gene Tree for ACIN1

    Paralogs
    for ACIN1 gene

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

      User Feedback    		  --

    Genomic Variants
    for ACIN1 gene

    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Genotyping Reagents from Applied Biosystems)
    About This Section

      User Feedback
    10/193 NCBI SNPs in ACIN1 are shown (see all 193 )
    (Click "" for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 103)
    ABGenomic DataTranscription Related DataAllele Frequencies
    SNP IDValidChr 14 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    ""
    rs18850971,2
    		C,F,O,A23549319(+) CTGAGA/C/G/T 
                TACTA     		12 T P A S mis1 ref1 ese3""28""NA EA MN NS WA 3964""
    --
    rs115558031,2
    		C,F23549948(-) TTCCAA/C/G/T 
                AAACC     		12 K T R I mis1 ref1""9""NS EA WA 862""
    ""
    rs617450811,2
    		C,F23564437(+) CTCGAA/C/G/T 
                TACCA     		12 N T S I ref1 mis1""1""NA 72""
    --
    rs617416191,2
    		C,F23548787(+) GAGAAA/C/G/T 
                GTGAA     		12 H P R L mis1 ref1""1""NA 72""
    ""
    rs125897481,2
    		C,H23549510(+) GCAGCA/GCTACA 6 A V ref1 mis1 ese3""1Minor allele frequency- G:0.00NA 2""
    --
    rs740369101,2
    		C,F23548798(+) CGTGAC/ACTTGA 6 /R /S ref1 mis1""2Minor allele frequency- A:0.11NA WA 122""
    ""
    rs38111821,2
    		C,F23549785(-) GAGATA/C/G/T 
                CCTAG     		12 I M ref1 syn1 mis1 ese3""12""EA NS NA WA 2342""
    ""
    rs37515011,2
    		C,F23549285(+) AAGGAA/C/G/T 
                ACAGG     		12 Y S C F mis1 ref1 ese3""14""EA NS 2830""
    --
    rs9417191,2
    		C,H23549379(+) GACAGG/CGGGGG 6 /P /A ref1 mis1 ese3""8Minor allele frequency- C:0.00MN EA NS NA 490""
    --
    rs38410351,2
    		C23549879(-) GAGGA-/GGAAGAAG 6 E EE fra1 ref1""0--------
    About this table

    HapMap Linkage Disequilibrium images for ACIN1 (up to first 250kb)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)  ""
          Database of Genomic Variants (DGV) variations for ACIN1: --

    Disorders & Mutations
    for ACIN1 gene

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

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    "" ACIN1 for disorders           About GeneDecksing

    OMIM: 604562

    7 ""Novoseek disease relationships for ACIN1 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    adenocarcinoma lung 3.57 2 17409846 (2)
    leukemia 3.29 4 19668232 (4)
    nuclear alteration 2.51 1 16537548 (1)
    tumor growth 1.94 2 19644955 (2)
    bronchioloalveolar carcinoma 1.86 1 17409846 (1)
    adenocarcinoma 1.59 2 17409846 (2)
    prostate cancer 0.36 1 19644955 (1)
    About this table

    Medical News
    for ACIN1 gene

    (Possibly Related Articles in Doctor's Guide)
    About This Section

      User Feedback    		   --

    Publications
    for ACIN1 gene

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
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      User Feedback    		10/47 PubMed articles for ACIN1 gene (see all 47 ):

    Search for ACIN1 gene

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    Genome Databases showing ACIN1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 22985 HGNC: 17066 AceView: ACIN1 Ensembl:ENSG00000100813 euGenes: HUgn22985
    ECgene: ACIN1 Kegg: 22985 H-InvDB: ACIN1

    Other Databases showing ACIN1 gene

    (According to HUGE)
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    HUGE: KIAA0670

    Specialized Databases showing ACIN1 gene

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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    Intellectual Property
    for ACIN1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
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      User Feedback    		Patent Information for ACIN1 gene: ""
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    Services
    for ACIN1 gene

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Novus Biologicals,
    Epitomics, Sigma-Aldrich, R&D Systems, SABiosciences, Millipore, Abnova,
    Clones available from OriGene, Sigma-Aldrich, Sino Biological, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience)
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