ACER2 Gene
protein-coding GIFtS : 52 GCID: GC09 P019408
alkaline ceramidase 2 N-acylsphingosine amidohydrolase 3-like )ASAH3L )
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Aliasesfor ACER2 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Alkaline Ceramidase 2 1 2 FLJ415871 ASAH3L1 2 3 ALKCDase22 N-Acylsphingosine Amidohydrolase 3-Like1 3 Ceramide Hydrolase2 Alkaline CDase 22 3 EC 3.5.1.233 AlkCDase 22 3 Acylsphingosine Deacylase 3-Like3 HaCER21
Export aliases for ACER2 gene to outside databases Previous GC identifer: GC09P019400
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Summariesfor ACER2 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for ACER2 : The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 (PubMed 16940153)).(supplied by OMIM, Jul 2010) UniProtKB/Swiss-Prot: ACER2_HUMAN, Q5QJU3 Function : Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. Unsaturated long-chain ceramidesare the best substrates, saturated long-chain ceramides and unsaturated very long-chain ceramides are good substrates, whereas saturated very long-chain ceramides and short-chain ceramides were poor substrates. The substrate preference is D-erythro-C(18:1)-, C(20:1)-, C(20:4)-ceramide > D-erythro-C(16:0)-, C(18:0), C(20:0)-ceramide > D-erythro-C(24:1)-ceramide > D-erythro-C(12:0)-ceramide, D-erythro-C(14:0)-ceramides > D-erythro-C(24:0)-ceramide > D-erythro-C(6:0)-ceramide. Inhibits the maturation of protein glycosylation in the Golgi complex, including that of integrin beta-1 (ITGB1) and of LAMP1, by increasing the levels of sphingosine. Inhibits cell adhesion by reducing the level of ITGB1 in the cell surface. May have a role in cell proliferation and apoptosis that seems to depend on the balance between sphingosine and sphingosine-1-phosphate Gene Wiki entry for ACER2
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Genomic Viewsfor ACER2 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000009.11 NC_018920.1 NT_008413.18 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ACER2 gene promoter:Elk-1 USF1 GATA-3 AP-1 LCR-F1 GATA-1 GATA-2 USF-1 FOXJ2 (long isoform) FOXJ2 Other transcription factors Search SABiosciences Chromatin IP Primers for ACER2 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 9p22.1 Ensembl cytogenetic band: 9p22.1 HGNC cytogenetic band: 9p21.3 ACER2 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 9 GeneLoc Exon Structure
GeneLoc location for GC09P019408: view genomic region
(about GC identifiers )
Start: 19,408,925 bp from pter End:
19,452,500 bp from pter
Size: 43,576 bases Orientation:
plus strand
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Proteinsfor ACER2 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: ACER2_HUMAN, Q5QJU3 See
protein sequence )Recommended Name: Size : 275 amino acids; 31309 DaSubcellular location : Golgi apparatus membrane; Multi-pass membrane proteinSecondary accessions : A2A3R8 Q569G5 Q5VZR7 Q71RD2Alternative splicing : 3 isoforms : Q5QJU3-1 Q5QJU3-2 Q5QJU3-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ACER2: NX_Q5QJU3 ACER2 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_001010887.2 ENSEMBL proteins: ENSP00000342609 ENSP00000369735 Reactome Protein details: Q5QJU3 Human Recombinant Protein Products: Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing ACER2 Antibody Products: Assay Products for ACER2:
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Protein
Domains /for ACER2 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q5QJU3 ProtoNet protein and cluster: Q5QJU3
1 Blocks protein family : IPB008901 UniProtKB/Swiss-Prot: ACER2_HUMAN, Q5QJU3 Similarity : Belongs to the alkaline ceramidase family
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Functionfor ACER2 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: ACER2_HUMAN, Q5QJU3 Function : Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. Unsaturated long-chain ceramidesare the best substrates, saturated long-chain ceramides and unsaturated very long-chain ceramides are good substrates, whereas saturated very long-chain ceramides and short-chain ceramides were poor substrates. The substrate preference is D-erythro-C(18:1)-, C(20:1)-, C(20:4)-ceramide > D-erythro-C(16:0)-, C(18:0), C(20:0)-ceramide > D-erythro-C(24:1)-ceramide > D-erythro-C(12:0)-ceramide, D-erythro-C(14:0)-ceramides > D-erythro-C(24:0)-ceramide > D-erythro-C(6:0)-ceramide. Inhibits the maturation of protein glycosylation in the Golgi complex, including that of integrin beta-1 (ITGB1) and of LAMP1, by increasing the levels of sphingosine. Inhibits cell adhesion by reducing the level of ITGB1 in the cell surface. May have a role in cell proliferation and apoptosis that seems to depend on the balance between sphingosine and sphingosine-1-phosphate Catalytic activity : N-acylsphingosine + H(2)O = a carboxylate + sphingosineEnzyme regulation : Specifically activated by lumenal, but not cytosolic Ca(2+). Inhibited by Zn(2+) or Cu(2+). Mg(2+)or Mn(2+) have no effect on ceramidase activity Biophysicochemical properties : Kinetic parameters: KM=81 uM for D-erythro-C(24:1)-ceramide (at 37 degrees Celsius andpH 9.0); Vmax=27 pmol/min/mg enzyme with D-erythro-C(24:1)-ceramide as substrate; pH dependence: Optimum pH is 7.5-9.0; Enzyme Number (IUBMB): EC 3.5.1.23 1
Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 3 )human mouse rat OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: ACER2 (NM_001010887 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACER2 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ACER2
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACER2
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
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Pathways & Interactionsfor ACER2 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways About this table See pathways by source Super-pathway contained gene-specific pathways 1 Sphingolipid metabolism 2 Metabolism 3 sphingosine and sphingosine-1-phosphate metabolism
Pathway sources See GeneCards unified pathways Show all pathways 1 4 2 (Kegg details for ACER2) :About GeneDecksing Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ACER2 STRING Interaction
Network Preview (showing 5 interactants - click image to see 21)5/21 Interacting proteins for ACER2 (ENSP00000342609 4 via UniProtKB, MINT, STRING , and/or I2D (see all 21 )About this table Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14 ): About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0001953 negative regulation of cell-matrix adhesion
IDA 18945876 GO:0006644 phospholipid metabolic process
TAS -- GO:0006665 sphingolipid metabolic process
TAS -- GO:0006672 ceramide metabolic process
IEA -- GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
IMP --
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Drugs & Compoundsfor ACER2 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for ACER2 10/123 HMDB Compounds for ACER2 (see all 123 )About this table ACER2
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Transcriptsfor ACER2 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for ACER2 gene: NM_001010887.2 Unigene Cluster for ACER2:
Alkaline ceramidase 2 Hs.41379 [show with all ESTs ] Unigene Representative Sequence: AK123581 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000340967 (uc003znx.1 uc003zny.1 uc003znz.1 ) ENST00000380376 Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 3 )human mouse rat OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: ACER2 (NM_001010887 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACER2 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ACER2
Additional cDNA sequence: AF370405.1 AK123581.1 AY312516.1 BC092487.1
4 DOTS entries : DT.105839 DT.40290454
DT.100652251 DT.121154936 14 AceView cDNA sequences :
BX646596 BX112888 AI168043 AA309752 AK123581 AF370405 AI033878 BQ081995 CF593785 BX482955 BF839613 R96782 H90930 H90280 GeneLoc Exon Structure 2 Alternative Splicing Database (ASD) splice patterns (SP) for ACER2 About this scheme ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b SP1 : SP2 : -
ECgene alternative splicing isoforms for ACER2
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Expression for ACER2 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ACER2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: --
About this image ACER2 expression in embryonic tissues and stem cells About this table 1 LifeMap In Vivo Development Anatomical Compartment/CellTissue Category (developmental path) Heart Endocardium Heart Expression: Experimental details:
In-situ hybridization
See ACER2 Protein Expression from SPIRE MOPED and PaxDB SOURCE GeneReport for Unigene cluster: Hs.41379 UniProtKB/Swiss-Prot: ACER2_HUMAN, Q5QJU3 Tissue specificity : Highly expressed in placentaSABiosciences Custom PCR Arrays for ACER2 Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACER2
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Orthologsfor ACER2 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for ACER2 gene from 8/22 species (see all 22 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
chicken Aves ACER21
alkaline ceramidase 2
80.85(n) 90.55(a)
427235 XM_424820.2 XP_424820.2
lizard Reptilia ACER26
--
88(a)
1 ↔ 1
2(62424966-62450138)
African clawed frog Amphibia Xl.109892
Xenopus laevis transcribed sequence with weak similarity more
75.29(n)
BJ060795.1
zebrafish Actinopterygii LOC1003311791
alkaline ceramidase 2-like
73.06(n) 83.39(a)
100331179 XM_002663031.2 XP_002663077.1
fruit fly Insecta bwa1
brain washing
57.55(n) 49.61(a)
250736 NM_136176.2 NP_610020.1
worm Secernentea CELE_W02F12.21
Protein W02F12.2
43.44(n) 29.53(a)
189124 NM_072296.4 NP_504697.2
thale cress eudicotyledons ATCES16
dihydroceramidase
21(a)
1 → many
4(11797567-11799856)
rice Liliopsida --
alkaline phytoceramidase, putative, expressed
24(a)
1 → many
3(28008018-28011928)
ENSEMBL Gene Tree for ACER2 (if available)TreeFam Gene Tree for ACER2 (if available)
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Paralogsfor ACER2 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for ACER2 gene ACER3 2 ACER1 2 1 SIMAP similar gene for ACER2 using alignment to 1 protein entry: ACER2_HUMAN :ACER1 About GeneDecksing 1 Pseudogenes.org Pseudogene for ACER2 PGOHUM00000240501
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Genomic Variantsfor ACER2 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 9 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for ACER2 (19408925 - 19452500 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for ACER2 2 CNVs 95870 52762
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor ACER2 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 613492
OMIM disorders : --4 : About MalaCards farber lipogranulomatosis lipogranulomatosis retinal degeneration retinitis 1 disease from the University of Copenhagen DISEASES database for ACER2 :Farber lipogranulomatosis Human Genome Epidemiology (HuGE) Navigator: ACER2 (1 document)Export disorders for ACER2 gene to outside databases
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Publicationsfor ACER2 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ACER2 gene, integrated from 9 sources (see all 12 ):(articles sorted by number of sources associating them with ACER2) Utopia : connect your pdf to the dynamic
Alkaline ceramidase 2 regulates beta1 integrin maturation and cell adhesion. (PubMed id 18945876) 1 , 2 , 3, 9(2009) Substrate specificity, membrane topology, and activit y regulation of human alkaline ceramidase 2 (ACER2). (PubMed id 20089856) 1 , 2 , 9(2010) Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P. (PubMed id 16940153) 1 , 2 (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) DNA sequence and analysis of human chromosome 9. (PubMed id 15164053) 1 , 2 (2004) Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874) 1 , 2 (2004) Alkaline ceramidase 2 (ACER2) and its product dihydro sphingosine mediate the cytotoxicity of N-(4-hydroxyphenyl)retinamide in tumor cells. (PubMed id 20628055) 1 (2010) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 (2010) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 (2002) Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis. (PubMed id 20068046) 9 Hu W....Mao C. (2010)
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External Searches for ACER2 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ACER2 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing ACER2 gene
(According to HUGE )
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Specialized Databases showing ACER2 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for ACER2 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for ACER2 gene: ACER2 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ACER2 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for ACER2 OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for ACER2 OriGene 3'-UTR Clone for ACER2 OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for ACER2 OriGene Custom Protein Services for ACER2 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ACER2 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Search Tocris compounds for ACER2
ACER2 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACER2
Search ThermoFisher Antibodies for ACER2
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ACER2
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Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Anatomical Compartment 
Negative
Selective marker
Curated
Microarrays
