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ACE Gene

protein-coding   GIFtS: 72
GCID: GC17P061554

Angiotensin I Converting Enzyme

(Previous name: angiotensin I converting enzyme (peptidyl-dipeptidase A)...)
(Previous symbol: DCP1)
  See ACE-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Angiotensin I Converting Enzyme1 2     CD1432
DCP11 2 3 5     Angiotensin Converting Enzyme, Somatic Isoform2
Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 11 2     Angiotensin I Converting Enzyme Peptidyl-Dipeptidase A 1 Transcript2
Dipeptidyl Carboxypeptidase I2 3     Angiotensin-Converting Enzyme2
Kininase II2 3     carboxycathepsin2
DCP2 3     Dipeptidyl Carboxypeptidase 12
CD143 Antigen2 3     Peptidase P2
ACE12 5     Testicular ECA2
ICH2 5     EC 3.2.1.-3
MVCD32 5     EC 3.4.15.13
Peptidyl-Dipeptidase A1     

External Ids:    HGNC: 27071   Entrez Gene: 16362   Ensembl: ENSG000001596407   OMIM: 1061805   UniProtKB: P128213   

Export aliases for ACE gene to outside databases

Previous GC identifers: GC17P061205 GC17P063980 GC17P061895 GC17P062027 GC17P058908 GC17P056922


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ACE Gene:
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active
peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls
blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many
studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of
circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants
encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form
and the testicular form, respectively, that are equally active. (provided by RefSeq, May 2010)

GeneCards Summary for ACE Gene:
ACE (angiotensin I converting enzyme) is a protein-coding gene. Diseases associated with ACE include neurosarcoidosis, and renal tubular dysgenesis, ace-related. GO annotations related to this gene include drug binding and actin binding. An important paralog of this gene is TMEM27.

UniProtKB/Swiss-Prot: ACE_HUMAN, P12821
Function: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase
of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has
also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose
linkage in the GPI moiety

summary for ACE Gene:
Angiotensin-converting enzyme (ACE, aka peptidyl dipeptidase A, carboxycathepsin) cleaves a C-terminal
dipeptide from angiotensin I to create the vasoconstrictor peptide, angiotensin II. ACE can also inactivate
the vasodilator peptide, bradykinin. There are two isoforms of ACE, a smaller/single catalytic site enzyme
found in the testes and a more widely expressed ~180kDa dual active site isoform. ACE is often membrane
bound. In contrast to ACE, the homolog ACE2, has recently been shown to cleave and inactivate angiotensin II
to generate the vasodilator Angiotensin (1-7). ACE inhibitors are widely used to treat hypertension and
cardiovascular diseases. ACE inhibitors have also been used to slow nephropathy, particularly when it is
associated with diabetes.

Gene Wiki entry for ACE (Angiotensin-converting enzyme) Gene

PharmGKB "VIP" summary for ACE


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ACE gene promoter:
         Sp1   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ACE promoter sequence
   Search Chromatin IP Primers for ACE

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ACE


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q23.3   Ensembl cytogenetic band:  17q23.3   HGNC cytogenetic band: 17q23.3

ACE Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACE gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P061554:  view genomic region     (about GC identifiers)

Start:
61,554,422 bp from pter      End:
61,599,205 bp from pter
Size:
44,784 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ACE_HUMAN, P12821 (See protein sequence)
Recommended Name: Angiotensin-converting enzyme precursor  
Size: 1306 amino acids; 149715 Da
Cofactor: Binds 2 zinc ions per subunit. Isoform Testis-specific only binds 1 zinc ion per subunit
Cofactor: Binds 3 chloride ions per subunit
Miscellaneous: Inhibitors of ACE are commonly used to treat hypertension and some types of renal and cardiac
dysfunction
Miscellaneous: The glycosidase activity probably uses different active site residues than the metalloprotease
activity
Sequence caution: Sequence=BAD92208.1; Type=Erroneous initiation;
Selected PDB 3D structures from and Proteopedia for ACE (see all 26):
1O86 (3D)        1O8A (3D)        1UZE (3D)        1UZF (3D)        2C6F (3D)        2C6N (3D)    
Secondary accessions: B0LPF0 B4DXI3 E7EU16 P22966 Q53YX9 Q59GY8 Q7M4L4
Alternative splicing: 4 isoforms:  P12821-1   P12821-2   P12821-3, P22966-1   P12821-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ACE: NX_P12821

Explore proteomics data for ACE at MOPED

Post-translational modifications: 

  • Phosphorylated by CK2 on Ser-1299; which allows membrane retention1
  • Glycosylation2 at Asn38, Asn54, Asn74, Asn111, Asn146, Asn160, Asn318, Asn445, Asn509, Asn677,
                                 Asn695, Asn714, Asn760, Asn942, Asn1191
  • Modification sites at PhosphoSitePlus

  • See ACE Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_000780.1  NP_001171528.1  NP_690043.1  

    ENSEMBL proteins: 
     ENSP00000462995   ENSP00000290866   ENSP00000462280   ENSP00000463302   ENSP00000463673  
     ENSP00000290863   ENSP00000462002   ENSP00000462110   ENSP00000392247   ENSP00000462599  
     ENSP00000464629   ENSP00000462909   ENSP00000464428   ENSP00000397593   ENSP00000439591  
     ENSP00000464539   ENSP00000387760  
    Reactome Protein details: P12821

    ACE Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for ACE (ACE/CD143)
    Enzo Life Sciences proteins for ACE
    OriGene Purified Protein for ACE
    OriGene Protein Over-expression Lysate for ACE
    OriGene MassSpec for ACE
    OriGene Custom Protein Services for ACE
    GenScript Custom Purified and Recombinant Proteins Services for ACE
    Novus Biologicals ACE Protein
    Novus Biologicals ACE Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ACE

     
    Search eBioscience for Proteins for ACE 

    ACE Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of ACE
    R&D Systems Antibodies for ACE (ACE/CD143)
    OriGene Antibodies for ACE
    OriGene Custom Antibody Services for ACE
    Novus Biologicals ACE Antibodies
    Abcam antibodies for ACE
    Cloud-Clone Corp. Antibodies for ACE
    ThermoFisher Antibodies for ACE
    LSBio Antibodies in human, mouse, rat for ACE

    ACE Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ACE
    R&D Systems ELISAs for ACE (ACE/CD143)         (see all)
    GenScript ACE-Activity-based Protease?src=genec Assay for Compound Screening
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ACE
    Cloud-Clone Corp. CLIAs for ACE
    Search eBioscience for ELISAs for ACE 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CD: CD molecules

    IUPHAR Guide to PHARMACOLOGY protein family classification: Angiotensin-converting enzyme 1
    Endopeptidases

    1 InterPro protein domain:
     IPR001548 Peptidase_M2

    Graphical View of Domain Structure for InterPro Entry P12821

    ProtoNet protein and cluster: P12821

    1 Blocks protein domain: IPB001548 Peptidyl-dipeptidase A (M2) metalloprotease family signature

    UniProtKB/Swiss-Prot: ACE_HUMAN, P12821
    Similarity: Belongs to the peptidase M2 family


    Find genes that share domains with ACE           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ACE_HUMAN, P12821
    Function: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase
    of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has
    also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose
    linkage in the GPI moiety
    Catalytic activity: Release of a C-terminal dipeptide, oligopeptide- -Xaa-Yaa, when Xaa is not Pro, and Yaa is
    neither Asp nor Glu. Thus, conversion of angiotensin I to angiotensin II, with increase in vasoconstrictor
    activity, but no action on angiotensin II
    Enzyme regulation: Strongly activated by chloride. Specifically inhibited by lisinopril, captopril and enalaprilat
    Biophysicochemical properties: Kinetic parameters: KM=2.51 mM for Hip-His-Leu;
    Induction: Up-regulated in failing heart

         Enzyme Numbers (IUBMB): EC 3.2.1.-1 EC 3.4.15.11

         Gene Ontology (GO): Selected molecular function terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IDA16186248
    GO:0004175endopeptidase activity IDA15283675
    GO:0004180carboxypeptidase activity IEA--
    GO:0005515protein binding IPI16186248
    GO:0008144drug binding IDA1320019
         
    Find genes that share ontologies with ACE           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ACE:
     Increased gamma-H2AX phosphory 

         14 MGI mutant phenotypes (inferred from 14 alleles(MGI details for Ace):
     adipose tissue  behavior/neurological  cardiovascular system  cellular  endocrine/exocrine gland 
     growth/size/body  hematopoietic system  homeostasis/metabolism  immune system  liver/biliary system 
     mortality/aging  renal/urinary system  reproductive system  tumorigenesis 

    Find genes that share phenotypes with ACE           About GenesLikeMe

    Animal Models:
         MGI mouse knock-outs for ACE: Acetm1Mcf Acetm1Unc Acetm2Unc Acetm1Keb Acetm4Keb Acetm2Keb

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ACE
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ACE

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ACE
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ACE

    miRNA
    Products:
        
    miRTarBase miRNAs that target ACE:
    hsa-mir-335-5p (MIRT018383)

    Block miRNA regulation of human, mouse, rat ACE using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ACE (see all 9):
    hsa-miR-4297 hsa-miR-27a hsa-miR-513a-5p hsa-miR-340 hsa-miR-3126-5p hsa-miR-3119 hsa-miR-630 hsa-miR-1286
    SwitchGear 3'UTR luciferase reporter plasmidACE 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ACE
    Predesigned siRNA for gene silencing in human, mouse, rat ACE

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ACE

    Clone
    Products:
         
    OriGene clones in human, mouse for ACE (see all 21)
    OriGene ORF clones in mouse, rat for ACE
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): ACE (NM_000789)
    Sino Biological Human cDNA Clone for ACE
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACE
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACE

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ACE
    Browse ESI BIO Cell Lines and PureStem Progenitors for ACE 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACE


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ACE_HUMAN, P12821: Angiotensin-converting enzyme, soluble form: Secreted
    ACE_HUMAN, P12821: Cell membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    plasma membrane5
    endosome4
    nucleus3
    cytoskeleton2
    endoplasmic reticulum2
    mitochondrion2
    peroxisome2
    cytosol1
    golgi apparatus1
    lysosome1

    Gene Ontology (GO): Selected cellular component terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IDA15283675
    GO:0005768endosome IDA17077303
    GO:0005886plasma membrane TAS--
    GO:0009897external side of plasma membrane IDA9449382

    Find genes that share ontologies with ACE           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ACE About   (see all 8)  
    See pathways by source

    SuperPathContained pathways About
    1Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics
    Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics0.37
    ACE Inhibitor Pathway, Pharmacodynamics0.00
    Renin-angiotensin system0.37
    ACE Inhibitor Pathway0.00
    2Peptide hormone metabolism
    Peptide hormone metabolism0.30
    Metabolism of Angiotensinogen to Angiotensins0.00
    3Hypertrophic cardiomyopathy (HCM)
    Hypertrophic cardiomyopathy (HCM)0.75
    4p70S6K Signaling
    Renin-Angiotensin Pathway0.60
    5Toll-like receptor signaling pathway
    Chagas disease (American trypanosomiasis)0.32


    Find genes that share SuperPaths with ACE           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 R&D Systems Pathways for ACE
        A-beta Uptake & Degradation
    A-beta Plaque Formation & APP Metabolism

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for ACE
        Renin-Angiotensin Pathway

    1 GeneGo (Thomson Reuters) Pathway for ACE
        Transcription CREM signaling in testis

    1 BioSystems Pathway for ACE
        ACE Inhibitor Pathway


    1 Reactome Pathway for ACE
        Metabolism of Angiotensinogen to Angiotensins

    2 PharmGKB Pathways for ACE
        ACE Inhibitor Pathway, Pharmacodynamics
    Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics

    3 Kegg Pathways  (Kegg details for ACE):
        Renin-angiotensin system
    Chagas disease (American trypanosomiasis)
    Hypertrophic cardiomyopathy (HCM)

        Pathway & Disease-focused RT2 Profiler PCR Arrays including ACE: 
              Hypertension in human mouse rat
              Endothelial Cell Biology in human mouse rat
              Atherosclerosis in human mouse rat
              Diabetes in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for ACE

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for ACE (P128213 ENSP000002908664) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AGTR2P500523, ENSP000003609734I2D: score=1 STRING: ENSP00000360973
    COMTP219643, ENSP000003545114I2D: score=1 STRING: ENSP00000354511
    BDKRB2P304113, ENSP000003077134I2D: score=1 STRING: ENSP00000307713
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    ACE2ENSP000002525194STRING: ENSP00000252519
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 17):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001822kidney development IMP16116425
    GO:0001974blood vessel remodeling IC1668266
    GO:0002003angiotensin maturation TAS--
    GO:0002005angiotensin catabolic process in blood IC1668266
    GO:0002019regulation of renal output by angiotensin IC1668266

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    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Enzo Life Sciences drugs & compounds for ACE
      Browse compounds at ApexBio 

    Compounds for ACE available from Tocris Bioscience    About this table
    CompoundAction CAS #
    Benazepril hydrochlorideAngiotensin-converting enzyme (ACE) inhibitor[86541-74-4]
    Moexipril hydrochlorideAngiotensin-converting enzyme (ACE) inhibitor[82586-52-5]
    Perindopril erbumineAngiotensin-converting enzyme (ACE) inhibitor[107133-36-8]

    5 HMDB Compounds for ACE    About this table
    CompoundSynonyms CAS #PubMed Ids
    Angiotensin IIHypertensin (see all 11)11128-99-7--
    BradykininCallidin I (see all 5)58-82-2--
    ChlorineCl2 (see all 13)16887-00-6--
    LisinoprilAcerbon (see all 34)83915-83-7--
    ZincZinc (see all 2)7440-66-6--

    Selected DrugBank Compounds for ACE (see all 17)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    CaptoprilCaptoprilum [INN-Latin] (see all 3)62571-86-2targetinhibitor20014331 17618628 11929321 11030016 15236580 11752352 16889963
    Cilazapril-- 92077-78-6targetinhibitor18423812 10398211 1382157 11752352 10446934 1382161 10205231
    Lisinopril-- 83915-83-7targetinhibitor17618628 9506845 11929321 11030016 11752352
    Spirapril-- 83647-97-6targetinhibitor11929321 20524801 11752352 12613273 16126915
    EnalaprilEnalapril Maleate (see all 4)75847-73-3targetinhibitor17618628 16424790 15236580 11752352
    Fosinopril-- 98048-97-6targetinhibitor2836111 11329095 11030016 11752352
    MoexiprilMoexipril HCl (see all 3)103775-10-6targetinhibitor7473177 11929321 11752352 15286086
    Perindopril-- 107133-36-8targetinhibitor16370923 11929321 11752352 19379059
    QuinaprilQuinapril HCl (see all 3)85441-61-8targetinhibitor11929321 11752352 3020249 11817979
    Ramipril-- 87333-19-5targetinhibitor16398929 11929321 11030016 11752352

    1 IUPHAR Ligand for ACE (Angiotensin-converting enzyme 1)    About this table
    LigandTypeActionAffinityPubmed IDs
    captopril
    InhibitorInhibition--

    Selected Novoseek inferred chemical compound relationships for ACE gene (see all 127)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    enalapril 93.5 720 7742150 (6), 11205963 (5), 1330361 (4), 9723634 (4) (see all 99)
    captopril 92.7 883 1847704 (5), 16394648 (5), 1330361 (4), 8074019 (4) (see all 99)
    lisinopril 92.4 420 9061270 (4), 1327597 (4), 8891468 (4), 18483087 (4) (see all 99)
    ramipril 91.6 389 12423701 (4), 1837563 (3), 1725019 (3), 12639174 (3) (see all 99)
    perindopril 90.3 384 9236432 (6), 1327597 (5), 19379059 (5), 10800878 (4) (see all 99)
    fosinopril 88.4 164 1646240 (4), 7919557 (3), 8861547 (3), 8934359 (3) (see all 98)
    quinapril 88.3 255 7527326 (7), 9049577 (5), 10024837 (4), 2068835 (4) (see all 99)
    enalaprilat 88.2 223 10082496 (4), 9815869 (4), 11827728 (3), 1656995 (3) (see all 99)
    trandolapril 86.4 138 7527095 (5), 9829159 (4), 12669106 (3), 17711535 (3) (see all 93)
    cilazapril 85.9 145 7614501 (4), 11108164 (4), 1689417 (3), 2139303 (3) (see all 97)

    Selected PharmGKB related drug/compound annotations for ACE gene (see all 23)    About this table
    Drug/compound PharmGKB Annotation
    Beta Blocking AgentsCA  
    acetylcholineCA  
    amlodipineCA  
    antidepressantsCA  
    antiepilepticsCA  
    atorvastatinCA  
    benazeprilCA  
    bumetanideCA  
    calcium channel blockersCA  
    captoprilCA  



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    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ACE gene (4 alternative transcripts): 
    NM_000789.3  NM_001178057.1  NM_152830.2  NM_152831.1  

    Unigene Cluster for ACE:

    Angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
    Hs.298469  [show with all ESTs]
    Unigene Representative Sequence: JQ927553
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25):
    ENST00000583336 ENST00000584529 ENST00000582678(uc010ddu.2) ENST00000579462(uc010wph.2)
    ENST00000290866(uc002jau.2) ENST00000582627 ENST00000580318 ENST00000579726
    ENST00000290863(uc002jav.2 uc010wpj.2 uc010wpk.2) ENST00000582005
    ENST00000578839 ENST00000413513 ENST00000579314(uc010ddv.2) ENST00000579204
    ENST00000584865 ENST00000582761 ENST00000577418 ENST00000583645
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ACE using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ACE (see all 9):
    hsa-miR-4297 hsa-miR-27a hsa-miR-513a-5p hsa-miR-340 hsa-miR-3126-5p hsa-miR-3119 hsa-miR-630 hsa-miR-1286
    SwitchGear 3'UTR luciferase reporter plasmidACE 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ACE
    Predesigned siRNA for gene silencing in human, mouse, rat ACE
    Clone
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    OriGene clones in human, mouse for ACE (see all 21)
    OriGene ORF clones in mouse, rat for ACE
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): ACE (NM_000789)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACE
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACE
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ACE
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ACE
      QuantiTect SYBR Green Assays in human, mouse, rat ACE
      QuantiFast Probe-based Assays in human, mouse, rat ACE

    Additional mRNA sequence: 

    AB208971.1 AK296566.1 AK301988.1 J04144.1 JQ927553.1 M26657.1 S81361.1 X16295.1 

    13 DOTS entries:

    DT.450544  DT.95220519  DT.100790782  DT.75103816  DT.100790780  DT.86854701  DT.100790785  DT.95220571 
    DT.100770455  DT.100776952  DT.40116291  DT.95220617  DT.95322212 

    Selected AceView cDNA sequences (see all 223):

    BF196049 AW772446 AI096704 BM712523 AI371868 H27155 BE464066 BI826471 
    BF475825 BE382576 NM_152830 NM_152831 J04144 BE783248 AW772527 BG152896 
    BM984583 BQ881320 BQ020350 BI831717 NM_000789 CD364763 AW003214 BX380082 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ACE (see all 14)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b · 15c · 15d ^ 16a · 16b ^ 17 ^ 18a · 18b ^
    SP1:        -           -                                                                                   -     -     -     -           -     -           -   
    SP2:                                                                                                                                      -     -           -   
    SP3:                                                                                                                                      -     -           -   
    SP4:                                                                                                                          -           -     -           -   
    SP5:                                                                                                                                      -     -               

    ExUns: 19a · 19b · 19c ^ 20a · 20b ^ 21 ^ 22 ^ 23a · 23b ^ 24 ^ 25a · 25b ^ 26 ^ 27 ^ 28 ^ 29a · 29b
    SP1:  -                 -                                         -                                       
    SP2:  -                 -                                         -                                       
    SP3:  -                                                           -                                       
    SP4:  -                 -                                                                                 
    SP5:  -                 -                                                                                 


    ECgene alternative splicing isoforms for ACE

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ACE expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGAGAAGCT
    ACE Expression
    About this image


    ACE expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Kidney (Urinary System)    fully expand to see all 4 entries
             Proximal Tubule Cells Proximal Tubule
             Metanephros
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Fourth Ventricle
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    ACE Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ACE Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.298469

    UniProtKB/Swiss-Prot: ACE_HUMAN, P12821
    Tissue specificity: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system
    and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis

        Pathway & Disease-focused RT2 Profiler PCR Arrays including ACE: 
              Hypertension in human mouse rat
              Endothelial Cell Biology in human mouse rat
              Atherosclerosis in human mouse rat
              Diabetes in human mouse rat

    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ACE
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ACE
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    QuantiFast Probe-based Assays in human, mouse, rat ACE
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACE

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ACE gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ace1 , 5 angiotensin I converting enzyme (peptidyl-dipeptidase more1, 5 84.48(n)1
    83.86(a)1
      11 (68.84 cM)5
    114211  NM_207624.51  NP_997507.11 
     1059679455 
    chicken
    (Gallus gallus)
    Aves ACE1 angiotensin I converting enzyme (peptidyl-dipeptidase more 71.13(n)
    68.62(a)
      419953  NM_001167732.1  NP_001161204.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    65(a)
    1 → many
    6(61163031-61223313)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.57762 Transcribed sequence with weak similarity to protein more 77.22(n)    BQ526772.1 
    zebrafish
    (Danio rerio)
    Actinopterygii ace1 angiotensin I converting enzyme (peptidyl-dipeptidase more 67.1(n)
    65.7(a)
      565980  XM_689244.6  XP_694336.5 
    fruit fly
    (Drosophila melanogaster)
    Insecta Ance3 peptidyl-dipeptidase A 44(a)
    (best of 6)
      2 34E2   --
    worm
    (Caenorhabditis elegans)
    Secernentea acn-16
    Protein ACN-1, isoform a (acn-1) mRNA, complete cd...
    24(a)
    1 → many
    X(5092281-5097067) WBGene00000039


    ENSEMBL Gene Tree for ACE (if available)
    TreeFam Gene Tree for ACE (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ACE gene
    TMEM272  ENSG000002648132  ACE22  
    1 SIMAP similar gene for ACE using alignment to 21 protein entries:     ACE_HUMAN (see all proteins):
    ACE2

    Find genes that share paralogs with ACE           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ACE (see all 873)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1423282371,2
    C,Funtested162576747(+) CGCCTC/G/TGGCTT 2 S L mis11NA 4530
    rs43191,2
    C--61562490(+) CAGGG-/GCAGGG 3 -- int15Minor allele frequency- G:0.43NS CSA 682
    rs19738681,2
    C--61565725(+) agaaaG/Aaaaaa 3 -- int1 trp31Minor allele frequency- A:0.50WA 2
    rs17997631,2
    C--61575454(+) CATGACT/-CTCTG 3 -- ut311Minor allele frequency- -:0.00CSA 2
    rs1160037391,2
    C,F--62570158(+) CAATGC/G/TCCGCC 1 -- us2k11WA 118
    rs1831977121,2
    --62570206(+) GAGGCA/GAGGCC 1 -- us2k10--------
    rs1886071521,2
    --62570300(+) TTCAGA/GGGCTG 1 -- us2k10--------
    rs1995778711,2
    --62570351(+) TCCAC-/AGAAAGA 1 -- us2k10--------
    rs1922186741,2
    --62570391(+) TTTGCA/GCACAG 1 -- us2k10--------
    rs1844166471,2
    C--62570544(+) ACCAAA/C/TGTAGC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ACE (61554422 - 61599205 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ACE:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv273813CNV Insertion20981092
    esv270563CNV Insertion20981092
    nsv908682CNV Loss21882294
    nsv817771CNV Loss17921354
    nsv908683CNV Loss21882294
    nsv525599CNV Loss19592680

    Human Gene Mutation Database (HGMD): ACE
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ACE
    DNA2.0 Custom Variant and Variant Library Synthesis for ACE

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 106180   
    OMIM disorders: 104300  612624  267430  614519  
    UniProtKB/Swiss-Prot: ACE_HUMAN, P12821
  • Ischemic stroke (ISCHSTR) [MIM:601367]: A stroke is an acute neurologic event leading to death of neural
    tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes,
    resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of
    heterogeneous disorders with multiple genetic and environmental risk factors. Note=Disease susceptibility is
    associated with variations affecting the gene represented in this entry
  • Renal tubular dysgenesis (RTD) [MIM:267430]: Autosomal recessive severe disorder of renal tubular
    development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia
    from early-onset oligohydramnios (the Potter phenotype). Note=The disease is caused by mutations affecting the
    gene represented in this entry
  • Microvascular complications of diabetes 3 (MVCD3) [MIM:612624]: Pathological conditions that develop in
    numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic
    nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major
    cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased
    tissue ischemia and angiogenesis. Note=Disease susceptibility is associated with variations affecting the gene
    represented in this entry
  • Intracerebral hemorrhage (ICH) [MIM:614519]: A pathological condition characterized by bleeding into one
    or both cerebral hemispheres including the basal ganglia and the cerebral cortex. It is often associated with
    hypertension and craniocerebral trauma. Intracerebral bleeding is a common cause of stroke. Note=Disease
    susceptibility is associated with variations affecting the gene represented in this entry

  • Selected diseases for ACE (see all 79):    
    About MalaCards
    neurosarcoidosis    renal tubular dysgenesis, ace-related    microvascular complications of diabetes 3    sars, progression of
    stroke, hemorrhagic    mesangioproliferative glomerulopathy    hyporeninemic hypoaldosteronism    angioedema induced by ace inhibitors
    granulomatous dermatitis    moderate and severe traumatic brain injury    intestinal tuberculosis    hypertensive retinopathy
    left ventricular outflow tract obstruction    nephrosclerosis    kanzaki disease    hepatoportal sclerosis
    myocardial infarction 2    hypertension    alzheimer's disease    renovascular hypertension

    Selected diseases from the University of Copenhagen DISEASES database for ACE (see all 23):
    Hypertension     Heart disease     Proteinuria     Sarcoidosis
    Diabetes mellitus     Kidney failure     Cerebrovascular accident     Urticaria
    Atherosclerosis     Nephritis     Lung disease     Renal vascular disease
    Nephrotic syndrome     Hyperglycemia     Systemic scleroderma     Diabetic retinopathy
    Anemia     Anuria     Oligohydramnios     Hypokalemia

    Find genes that share disorders with ACE           About GenesLikeMe

    Selected Novoseek inferred disease relationships for ACE gene (see all 97)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    heart failure 90.4 2092 11835905 (6), 14622625 (6), 16285075 (6), 11723314 (5) (see all 99)
    diabetic nephropathies 86.7 543 19077419 (7), 12016801 (6), 10332539 (5), 9111155 (4) (see all 99)
    essential hypertension 86.5 448 8686957 (4), 9626985 (4), 8076423 (3), 16866021 (3) (see all 99)
    heart failure congestive 86.2 526 8682064 (4), 18458262 (4), 8863101 (3), 7527326 (3) (see all 99)
    renal disease 85.5 960 17506717 (6), 11258145 (5), 12501871 (5), 12570791 (5) (see all 99)
    proteinuria 83.4 467 17984482 (5), 9328608 (4), 9767545 (4), 11007831 (4) (see all 99)
    microalbuminuria 83.1 234 15944842 (7), 15449965 (5), 19720797 (4), 16095545 (4) (see all 99)
    myocardial infarction 82.6 869 10462466 (7), 7606755 (7), 9812182 (5), 8644984 (5) (see all 99)
    angioedema 82.6 431 15111379 (8), 17540310 (7), 10594491 (7), 9530537 (7) (see all 99)
    ventricular dysfunction left 82.5 278 10499559 (4), 8994996 (3), 8095738 (3), 8682064 (3) (see all 99)

    Genetic Association Database (GAD): ACE
    Human Genome Epidemiology (HuGE) Navigator: ACE (1727 documents)

    Export disorders for ACE gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ACE gene, integrated from 10 sources (see all 7660) (see top 10):
    (articles sorted by number of sources associating them with ACE)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme. (PubMed id 15236580)1, 2, 7, 9 Natesh R.... Acharya K.R. (Biochemistry 2004)
    2. Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. (PubMed id 15534175)1, 2, 4 Casas J.P.... Sharma P. (Arch. Neurol. 2004)
    3. Sequence variation in the human angiotensin converting enzyme. (PubMed id 10319862)1, 2, 3 Rieder M.J.... Nickerson D.A. (Nat. Genet. 1999)
    4. Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial angiotensin-converting enzyme. (PubMed id 2554286)1, 2, 3 Ehlers M.R.W.... Riordan J.F. (Proc. Natl. Acad. Sci. U.S.A. 1989)
    5. Shedding of somatic angiotensin-converting enzyme (ACE) is inefficient compared with testis ACE despite cleavage at identical stalk sites. (PubMed id 10769174)1, 2, 9 Woodman Z.L.... Sturrock E.D. (Biochem. J. 2000)
    6. A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE) unlinked to the ACE gene. (PubMed id 18544166)1, 4, 9 McKenzie C.A....Cooper R.S. (BMC Med Genomics 2008)
    7. Reduction of pneumonia risk by an angiotensin I-converting enzyme inhibitor in elderly Japanese inpatients according to insertion/deletion polymorphism of the angiotensin I-converting enzyme gene. (PubMed id 16202861)1, 4, 9 Takahashi T....Matsumoto M. (Am. J. Hypertens. 2005)
    8. The influence of mode of delivery and ACE genotype on serum angiotensin converting enzyme (ACE) activity in the mother and infant at term. (PubMed id 17123697)1, 4, 9 Uma R....Murphy D.J. (Eur. J. Obstet. Gynecol. Reprod. Biol. 2007)
    9. Angiotensin I-converting enzyme (ACE) inhibitors and restenosis after coronary artery stenting in patients with the DD genotype of the ACE gene. (PubMed id 12798565)1, 4, 9 Koch W....Kastrati A. (J. Am. Coll. Cardiol. 2003)
    10. Serum angiotensin I-converting enzyme is reduced in Crohn's disease and ulcerative colitis irrespective of genotype. (PubMed id 11569699)1, 4, 9 Matsuda T....Kawakami Y. (Am. J. Gastroenterol. 2001)
    11. [No relation between angiotensin-converting enzyme (ACE) inhibitor-induced cough and ACE gene polymorphism, plasma bradykinin, substance P and ACE inhibitor concentration in Japanese patients]. (PubMed id 11265121)1, 4, 9 Okumura H....Rikihisa T. (Yakugaku Zasshi 2001)
    12. [Relationship of the disease severity with ACE gene polymorphism and serum ACE activity in preterm infants]. (PubMed id 19102831)1, 4, 9 Han T.Y....Ye H.M. (Zhongguo Dang Dai Er Ke Za Zhi 2008)
    13. Angiotensin-converting enzyme levels and activity in Alzheimer's disease: differences in brain and CSF ACE and association with ACE1 genotypes. (PubMed id 19956428)1, 4, 9 Miners S....Kehoe P.G. (Am J Transl Res 2009)
    14. CK2 phosphorylates the angiotensin-converting enzyme and regulates its retention in the endothelial cell plasma membrane. (PubMed id 12386153)1, 2, 9 Kohlstedt K.... Fleming I. (Circ. Res. 2002)
    15. No evidence for association between the renin-angiotensin-aldosterone system and otosclerosis in a large Belgian-Dutch population. (PubMed id 19503013)1, 4, 9 Schrauwen I....Van Camp G. (amp 2009)
    16. Neutral endopeptidase and angiotensin I converting enzyme insertion/deletion gene polymorphism in humans. (PubMed id 14730327)1, 4, 9 Jalil J.E....Lavandero S. (J Hum Hypertens 2004)
    17. Hypertension after renal transplantation and polymorphism of genes involved in essential hypertension: ACE, AGT, AT1 R and ecNOS. (PubMed id 11926202)1, 4, 9 Basset e.l.-.E.A....Berthou F. (Clin. Nephrol. 2002)
    18. The role of ace gene polymorphism in the development of angioedema secondary to angiotensin converting enzyme inhibitors and angiotensin II receptor blockers. (PubMed id 18680700)1, 4, 9 Gulec M....Karaayvaz M. (Allergol Immunopathol (Madr) 2008)
    19. ACE I/D polymorphism in Korean patients with ischemic stroke and silent brain infarction. (PubMed id 17922891)1, 4, 9 Hong S.H....Kim N.K. (Acta Neurol. Scand. 2008)
    20. Evaluation of the angiotensin-converting enzyme insertion/deletion polymorphism and the risk of ischaemic stroke. (PubMed id 16446094)1, 4, 9 Tuncer N....Kara I. (J Clin Neurosci 2006)
    21. [The hemostasis parameters and ACE gene polymorphism in patients with essential hypertension treated with perindopril]. (PubMed id 17131847)1, 4, 9 Janczak-Bazan A. (Ann Acad Med Stetin 2006)
    22. Polymorphisms in angiotensin II type 1 receptor and angiotensin I-converting enzyme genes and breast cancer risk among Chinese women in Singapore. (PubMed id 15498791)1, 4, 9 Koh W.P....Yu M.C. (Carcinogenesis 2005)
    23. [I/D polymorphism of angiotensin I converting enzyme gene and insulin resistance and some parameters of metabolic syndrome in patients with type 2 diabetes]. (PubMed id 16789486)1, 4, 9 Moleda P....Pilarska K. (Pol. Arch. Med. Wewn. 2005)
    24. Effect of angiotensin-converting enzyme inhibition on restenosis after coronary stenting. (PubMed id 12521626)1, 4, 9 Ribichini F....Uslenghi E. (Am. J. Cardiol. 2003)
    25. The DD genotype of the ACE gene polymorphism is associated with diabetic nephropathy in the type-1 diabetics. (PubMed id 11428725)1, 4, 9 Azar S.T....Halabi G. (Endocr. Res. 2001)
    26. Angiotensin-converting enzyme activity and the ACE Alu polymorphism in autosomal dominant polycystic kidney disease. (PubMed id 11733623)1, 4, 9 Schiavello T....Thomas M. (Nephrol. Dial. Transplant. 2001)
    27. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. (PubMed id 10969042)1, 2, 9 Donoghue M.... Acton S. (Circ. Res. 2000)
    28. Endothelial nitric oxide synthase, angiotensin-converting enzyme and angiotensinogen gene polymorphisms in hypertensive disorders of pregnancy. (PubMed id 20186148)1, 4, 9 Aggarwal P.K....Jha V. (Hypertens. Res. 2010)
    29. Lack of association between renin-angiotensin system (RAS) polymorphisms and hypertension in Tunisian type 2 diabetics. (PubMed id 20415212)1, 4, 9 Arfa I....Abdelhak S. (Tunis Med 2010)
    30. Polymorphisms of angiotensin-converting enzyme (ACE) and ACE2 are not associated with orthostatic blood pressure dysregulation in hypertensive patients. (PubMed id 19684612)1, 4, 9 Fan X.H....Hui R.T. (Acta Pharmacol. Sin. 2009)
    31. Genetic variation in the renin-angiotensin system modifies the beneficial effects of ACE inhibitors on the risk of diabetes mellitus among hypertensives. (PubMed id 18563171)1, 4, 9 Bozkurt O....Klungel O.H. (J Hum Hypertens 2008)
    32. Association of angiotensin I-converting enzyme gene polymorphisms with aspirin intolerance in asthmatics. (PubMed id 18727619)1, 4, 9 Kim T.H....Shin H.D. (Clin. Exp. Allergy 2008)
    33. Angiotensin converting enzyme gene polymorphism (insertion/deletion) and hypertension in adult Asian Indians: a population-based study from Calcutta, India. (PubMed id 19130799)1, 4, 9 Das M....Ghosh A. (Hum. Biol. 2008)
    34. ACE gene polymorphism and losartan treatment in type 2 diabetic patients with nephropathy. (PubMed id 18199798)1, 4, 9 Parving H.H....Brenner B.M. (J. Am. Soc. Nephrol. 2008)
    35. Role of genetic polymorphisms in ACE and TNF-alpha gene in sarcoidosis: a meta-analysis. (PubMed id 17768594)1, 4, 9 Medica I....Peterlin B. (J. Hum. Genet. 2007)
    36. Angiotensin-converting enzyme gene polymorphism in chronic allograft nephropathy. (PubMed id 16797293)1, 4, 9 Biselli P.M....Pavarino-Bertelli E.C. (Transplant. Proc. 2006)
    37. Insertion/deletion polymorphism of angiotensin I converting enzyme gene and left ventricular hypertrophy in patients with type 2 diabetes mellitus. (PubMed id 17054027)1, 4, 9 Moleda P....Goracy I. (Kardiol Pol 2006)
    38. Circulating activities of angiotensin-converting enzyme, its homolog, angiotensin-converting enzyme 2, and neprilysin in a family study. (PubMed id 17000927)1, 4, 9 Rice G.I....Hooper N.M. (Hypertension 2006)
    39. [Association of polymorphic markers I/D of gene ACE and A1166C of gene AT2R1 with ischemic chronic heart failure in the Russian and Tatar populations of Bashkortostan Republic]. (PubMed id 17326392)1, 4, 9 Gubaev K.I....Mustafina O.E. (Genetika 2006)
    40. [Allelic variants of genes: angiotensin I-converting enzyme (ACE), angiotensin-II type 1 receptor (AT1R), methylenetetrahydrofolate reductase and left ventricular mass in patients with myocardial infarction]. (PubMed id 17274465)1, 4, 9 Goracy J....Ciechanowicz A. (Pol. Arch. Med. Wewn. 2006)
    41. Renin-angiotensin system gene polymorphisms: association with susceptibility to Henoch-Schonlein purpura and renal involvement. (PubMed id 16521052)1, 4, 9 Ozkaya O....HasanoA9lu E. (Clin. Rheumatol. 2006)
    42. No association between variants in the ACE and angiotensin II receptor 1 genes and acute mountain sickness in Nepalese pilgrims to the Janai Purnima Festival at 4380 m. (PubMed id 17173513)1, 4, 9 Koehle M.S....Rupert J.L. (amp 2006)
    43. [Angiotensin converting enzyme gene and exercise-induced silent myocardial ischemia in type 2 diabetes mellitus]. (PubMed id 15793788)1, 4, 9 Xing G....Zhao L. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2005)
    44. A study of the relationships between angiotensin- converting enzyme gene, chymase gene polymorphisms, pharmacological treatment with ACE inhibitor and regression of left ventricular hypertrophy in essential hypertension patients treated with benazepril. (PubMed id 15788353)1, 4, 9 He H....Hu Y.H. (Ann. Hum. Biol. 2005)
    45. Angiotensin converting enzyme gene polymorphism in Indian children with steroid sensitive nephrotic syndrome. (PubMed id 16272677)1, 4, 9 Patil S.J....Agrawal S. (Indian J Med Sci 2005)
    46. ACE insert/delete polymorphism and atherosclerosis. (PubMed id 15694930)1, 4, 9 Scheer W.D....Strong J.P. (Atherosclerosis 2005)
    47. Effects of genetic polymorphisms of the renin-angiotensin system in children with nephrotic syndrome. (PubMed id 16525944)1, 4, 9 Tabel Y....Yilmaz E. (J Renin Angiotensin Aldosterone Syst 2005)
    48. Angiotensin-I converting enzyme insertion/deletion polymorphism and its association with diabetic nephropathy: a meta-analysis of studies reported between 1994 and 2004 and comprising 14,727 subjects. (PubMed id 15830182)1, 4, 9 Ng D.P....Chia K.S. (Diabetologia 2005)
    49. Effects of ACE gene insertion/deletion polymorphism on response to spironolactone in patients with chronic heart failure. (PubMed id 15121491)1, 4, 9 Cicoira M....Zardini P. (Am. J. Med. 2004)
    50. Effects of perindopril treatment on hemostatic function in patients with essential hypertension in relation to angiotensin converting enzyme (ACE) and plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms. (PubMed id 15673060)1, 4, 9 Jastrzebskal M....Wesotowska T. (Nutr Metab Cardiovasc Dis 2004)
    51. Multiple Polymorphisms in the renin- angiotensin-aldosterone system (ACE, CYP11B2, AGTR1) and their contribution to hypertension in African Americans and Latinos in the multiethnic cohort. (PubMed id 15545843)1, 4, 9 Henderson S.O....Mack W. (Am. J. Med. Sci. 2004)
    52. Impact of angiotensin-converting enzyme gene polymorphism on neurohormonal responses to high- versus low-dose enalapril in advanced heart failure. (PubMed id 15523323)1, 4, 9 Tang W.H....Fowler M.B. (Am. Heart J. 2004)
    53. ACE2 gene expression is up-regulated in the human failing heart. (PubMed id 15151696)1, 2, 9 Goulter A.B.... Clark K.L. (BMC Med. 2004)
    54. [ACE and AGTR1 genes polymorphisms in left ventricular hypertrophy pathogenesis in humans]. (PubMed id 15612584)1, 4, 9 Makeeva O.A....Puzyrev V.P. (Mol. Biol. (Mosk.) 2004)
    55. Angiotensin-converting enzyme gene polymorphism, left ventricular remodeling, and exercise capacity in strength-trained athletes. (PubMed id 15799176)1, 4, 9 Kasikcioglu E....Peker I. (Heart Vessels 2004)
    56. [The relationship of angiotensin I-converting enzyme gene polymorphism with diabetic retinopathy and diabetes myocardial infarction]. (PubMed id 15192839)1, 4, 9 Wu S.S....Yi H.L. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2004)
    57. ACE gene polymorphism and progression of diabetic nephropathy in Korean type 2 diabetic patients: effect of ACE gene DD on the progression of diabetic nephropathy. (PubMed id 12722028)1, 4, 9 Ha S.K....Han D.S. (Am. J. Kidney Dis. 2003)
    58. The ACE gene I/D polymorphism is not associated with the blood pressure and cardiovascular benefits of ACE inhibition. (PubMed id 12925557)1, 4, 9 Harrap S.B....Woodward M. (Hypertension 2003)
    59. Cardiac hypertrophy and remodeling in relation to ACE and angiotensinogen genes genotypes in Chinese dialysis patients. (PubMed id 12675870)1, 4, 9 Wang A.Y....Sanderson J. (Kidney Int. 2003)
    60. Angiotensin-converting enzyme genotype, albuminuria and plasma fibrinogen in type 2 diabetes mellitus. (PubMed id 14740347)1, 4, 9 TkA!c I....Kalina I. (Wien. Klin. Wochenschr. 2003)
    61. The D-allele of the ACE polymorphism is related to increased QT dispersion in 609 patients after myocardial infarction. (PubMed id 11286523)1, 4, 9 Jeron A....Holmer S. (Eur. Heart J. 2001)
    62. The association study of DRD2, ACE and AGT gene polymorphisms and metamphetamine dependence. (PubMed id 11300226)1, 4, 9 SerA1 O....ZvolskA1 P. (Physiol Res 2001)
    63. Association of angiotensinogen M235T and A(-6)G gene polymorphisms with coronary heart disease with independence of essential hypertension: the PROCAGENE study. Prospective Cardiac Gene. (PubMed id 11345362)1, 4, 9 RodrA-guez-PAcrez J.C....Ferrario C.M. (J. Am. Coll. Cardiol. 2001)
    64. Angiotensin-converting enzyme (ACE) gene polymorphisms and familial occurrence of sarcoidosis. (PubMed id 11168787)1, 4, 9 SchA1rmann M....Schwinger E. (J. Intern. Med. 2001)
    65. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. (PubMed id 10924499)1, 2, 9 Tipnis S.R....Turner A.J. (J. Biol. Chem. 2000)
    66. Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction. (PubMed id 20230274)1, 4, 9 Kulminski A.M....Yashin A.I. (Rejuvenation Res 2010)
    67. ACE and AGTR1 polymorphisms and left ventricular hypertrophy in endurance athletes. (PubMed id 19997001)1, 4, 9 Di Mauro M....Gallina S. (Med Sci Sports Exerc 2010)
    68. ACE D/I polymorphism, migraine, and cardiovascular disease in women. (PubMed id 19221299)1, 4, 9 SchA1rks M....Kurth T. (Neurology 2009)
    69. Angiotensin-converting enzyme (ACE), angiotensinogen (AGT), and angiotensin II type 1 receptor (AT1R) gene polymorphisms in generalized aggressive periodontitis. (PubMed id 19162259)1, 4, 9 GA1rkan A....Berdeli A. (Arch. Oral Biol. 2009)
    70. Role of the ACE ID and MTHFR C677T polymorphisms in genetic susceptibility of migraine in a north Indian population. (PubMed id 19081115)1, 4, 9 Joshi G....Mittal B. (J. Neurol. Sci. 2009)
    71. ACE variants interact with the RAS pathway to confer risk and protection against type 2 diabetic nephropathy. (PubMed id 19108684)1, 4, 9 Ahluwalia T.S....Khullar M. (DNA Cell Biol. 2009)
    72. ACE gene polymorphism and cardiac structure in patients with insulin resistance. (PubMed id 18347926)1, 4, 9 Akin F....Gur S. (Mol. Biol. Rep. 2009)
    73. Association of angiotensin-converting enzyme activity and polymorphism with echocardiographic measures in familial and nonfamilial hypertrophic cardiomyopathy. (PubMed id 19390744)1, 4, 9 Buck P.C....Mady C. (Braz. J. Med. Biol. Res. 2009)
    74. Cost-effectiveness of ACE inhibitor therapy to prevent dialysis in nondiabetic nephropathy: influence of the ACE insertion/deletion polymorphism. (PubMed id 19696696)1, 4, 9 Vegter S....Postma M.J. (Pharmacogenet. Genomics 2009)
    75. [Comparative genetic analysis of different forms of low-renin arterial hypertension]. (PubMed id 18856058)1, 4, 9 Chikhladze N.M....Favorova O.O. (Mol. Biol. (Mosk.) 2008)
    76. The D allele of angiotensin I-converting enzyme gene insertion/deletion polymorphism is associated with the severity of atherosclerosis. (PubMed id 18298340)1, 4, 9 Niemiec P....Wita K. (Clin. Chem. Lab. Med. 2008)
    77. [Study on the association of predisposing genes with essential hypertension among Kazakhs ethnic group in Xinjiang]. (PubMed id 19103106)1, 4, 9 Chen X.D....Jin L. (Zhonghua Liu Xing Bing Xue Za Zhi 2008)
    78. Combined &quot;pro-atherosclerotic&quot; variants of the ACE and APOE genes increase the risk of the coronary artery disease associated with the presence of cigarette smoking. (PubMed id 19157170)1, 4, 9 Zak I....Krauze J. (Acta Cardiol 2008)
    79. Association of the angiotensinogen M235T and angiotensin-converting enzyme insertion/deletion gene polymorphisms in Turkish type 2 diabetic patients with and without nephropathy. (PubMed id 18413162)1, 4, 9 Eroglu Z....Tuzun M. (J. Diabetes Complicat. 2008)
    80. Angiotensin-converting enzyme gene insertion/deletion polymorphism in migraine patients. (PubMed id 18366776)1, 4, 9 Tronvik E....Schrader H. (BMC Neurol 2008)
    81. Influence of the ACE gene insertion/deletion polymorphism on insulin sensitivity and impaired glucose tolerance in healthy subjects. (PubMed id 18235053)1, 4, 9 Bonnet F....Walker M. (Diabetes Care 2008)
    82. Lack of association between the angiotensin-converting enzyme gene (I/D) polymorphism and diabetic nephropathy in Tunisian type 2 diabetic patients. (PubMed id 18404607)1, 4, 9 Arfa I....Abdelhak S. (J Renin Angiotensin Aldosterone Syst 2008)
    83. No association found between the insertion/deletion of a 287-bp alu repeat sequence within intron 16 of the angiotensin-I-converting enzyme (ACE) gene in Mexican patients and binary restenosis after coronary stenting. (PubMed id 18706898)1, 4, 9 MartA-nez-RA-os M.A....Vargas-AlarcA^n G. ( international journal of clinical chemistry 2008)
    84. [The relationship between the effect of amlodipine on carotid intimal-medial thickness and angiotensin converting enzyme genotypes in elderly hypertensive patients]. (PubMed id 19100063)1, 4, 9 Zhai L.H....Hu Y.H. (Zhonghua Xin Xue Guan Bing Za Zhi 2008)
    85. Prognostic value of the insertion/deletion polymorphism of the ACE gene in type 2 diabetic subjects: results from the Non-insulin-dependent Diabetes, Hypertension, Microalbuminuria or Proteinuria, Cardiovascular Events, and Ramipril (DIABHYCAR), Diabete de type 2, Nephropathie et Genetique (DIAB2NEPHROGENE), and Survie, Diabete de type 2 et Genetique (SURDIAGENE) studies. (PubMed id 18523145)1, 4, 9 Hadjadj S.... . (Diabetes Care 2008)
    86. Angiotensinogen and ACE gene polymorphisms and risk of atrial fibrillation in the general population. (PubMed id 18496132)1, 4, 9 Ravn L.S....Tybjaerg-Hansen A. (Pharmacogenet. Genomics 2008)
    87. Role of PC-1 and ACE genes on insulin resistance and cardiac mass in never-treated hypertensive patients. Suggestive evidence for a digenic additive modulation. (PubMed id 17367703)1, 4, 9 Perticone F....Trischitta V. (Nutr Metab Cardiovasc Dis 2007)
    88. Possible association of ACE gene I/D polymorphism with blood pressure--lowering response to hydrochlorothiazide. (PubMed id 18188985)1, 4, 9 Zhou Y....Liu G.F. (Biomed. Environ. Sci. 2007)
    89. Association of angiotensin-converting enzyme/DD genotype with sarcoidosis susceptibility in Slovenian patients. (PubMed id 18049432)1, 4, 9 Salobir B....Peterlin B. (Med. Sci. Monit. 2007)
    90. Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trial. (PubMed id 17885551)1, 4, 9 Bhatnagar V....Lipkowitz M.S. (J. Hypertens. 2007)
    91. Deletion polymorphism of the angiotensin I-converting enzyme gene in elderly patients with coronary heart disease. (PubMed id 17598398)1, 4, 9 MarkoviA8 B.B....MarkoviA8 M. (Coll Antropol 2007)
    92. Angiotensin converting enzyme genotype affects development and course of sarcoidosis in Asian Indians. (PubMed id 18496980)1, 4, 9 Tahir M....Mishra H.K. (Sarcoidosis Vasc Diffuse Lung Dis 2007)
    93. Association of ACE genotype and predominantly diastolic hypertension: a preliminary study. (PubMed id 17487825)1, 4, 9 JimAcnez P.M....OrA-as M. (J Renin Angiotensin Aldosterone Syst 2007)
    94. Polymorphisms in genes of the renin-angiotensin system and cerebral small vessel disease. (PubMed id 17124396)1, 4, 9 Gormley K....Markus H.S. (Cerebrovasc. Dis. 2007)
    95. Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy. (PubMed id 17143591)1, 4, 9 Osawa N....Maeda S. (J. Hum. Genet. 2007)
    96. A disease haplotype for advanced nephropathy in type 2 diabetes at the ACE locus. (PubMed id 16936219)1, 4, 9 Ng D.P....Krolewski A.S. (Diabetes 2006)
    97. Association of angiotensin I-converting enzyme gene insertion/deletion polymorphism and IgA nephropathy: a meta-analysis. (PubMed id 17124384)1, 4, 9 Yong D....Chao S.H. (Am. J. Nephrol. 2006)
    98. The relationship between ACE insertion/deletion polymorphism and coronary artery disease with or without myocardial infarction. (PubMed id 16303122)1, 4, 9 Seckin D....Ozbay Y. (Clin. Biochem. 2006)
    99. Antiproteinuric effect of losartan in non-diabetic renal disease is not dependent on ACE insertion/deletion polymorphism. (PubMed id 16960460)1, 4, 9 Park H.C....Han D.S. (amp 2006)
    100. Influence of ACE I/D gene polymorphism in the progression of renal failure in autosomal dominant polycystic kidney disease: a meta-analysis. (PubMed id 16935894)1, 4, 9 Pereira T.V....Krieger J.E. (Nephrol. Dial. Transplant. 2006)
    101. Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism. (PubMed id 16924268)1, 4, 9 Baghai T.C....Bondy B. (Mol. Psychiatry 2006)
    102. Association of ACE, ACE2 and UTS2 polymorphisms with essential hypertension in Han and Dongxiang populations from north-western China. (PubMed id 16866021)1, 4, 9 Yi L....Zhang D.L. (J. Int. Med. Res. 2006)
    103. [Polymorphism of angiotensin converting enzyme in Han populations and its relevance to the severity of coronary atherosclerosis]. (PubMed id 16764031)1, 4, 9 Shi Y.P....Xu G. (Zhejiang Da Xue Xue Bao Yi Xue Ban 2006)
    104. Myocardial infarction increases ACE2 expression in rat and humans. (PubMed id 15671045)1, 2, 9 Burrell L.M....Johnston C.I. (Eur. Heart J. 2005)
    105. The relationship between angiotensin converting enzyme gene polymorphism, coronary artery disease, and stent restenosis: the role of angiotensin converting enzyme inhibitors in stent restenosis in patients with diabetes mellitus. (PubMed id 16272779)1, 4, 9 Guneri S....Bozdemir V. (Int Heart J 2005)
    106. [Association of polymorphisms in ACE and CYP11B2 genes with antihypertensive effects of hydrochlorothiazide]. (PubMed id 16080804)1, 4, 9 Wu S.L....Song S.M. (Zhonghua Xin Xue Guan Bing Za Zhi 2005)
    107. Genotypic interactions of renin-angiotensin system genes in myocardial infarction. (PubMed id 16061119)1, 4, 9 AraA_jo M.A....Silva H.D. (Int. J. Cardiol. 2005)
    108. Effect of genetic variation on therapy with angiotensin converting enzyme inhibitors or angiotensin receptor blockers in dialysis patients. (PubMed id 15946912)1, 4, 9 BAPger C.A....KrAomer B.K. (Eur. J. Med. Res. 2005)
    109. [Association between angiotensin converting enzyme I/D polymorphism and high-sensitivity C-reactive protein in type 2 diabetic patients with atherosclerosis treated with ramipril]. (PubMed id 15958311)1, 4, 9 Wang L....Lin S.G. (Di Yi Jun Yi Da Xue Xue Bao 2005)
    110. [I/D relationship between polymorphism of ACE gene and progression of chronic glomerulonephritis]. (PubMed id 16078593)1, 4, 9 Kaliev R.R....Mirrakhimov M.M. (Ter. Arkh. 2005)
    111. Effect of 24-week treatment with telmisartan on myocardial structure and function: relationship to insertion/deletion polymorphism of the angiotensin-converting enzyme gene. (PubMed id 16222898)1, 4, 9 Conrady A.O....Panov A.V. (J. Int. Med. Res. 2005)
    112. Deletion/Deletion genotype of angiotensin-I converting enzyme gene is not associated with coronary artery disease in caucasians with type 2 diabetes. (PubMed id 16117314)1, 4, 9 Zorc-Pleskovic R....MilutinoviA8 A. (Coll Antropol 2005)
    113. Insertion/deletion polymorphism of the angiotensin-converting enzyme gene and preeclampsia in Japanese patients. (PubMed id 16052407)1, 4, 9 Kobashi G....Kondo K. (Semin. Thromb. Hemost. 2005)
    114. [Influence of angiotensin-converting enzyme gene polymorphism on the anti-proteinuria efficacy of angiotensin-converting enzyme inhibitor in Han nationality of southern Sichuan province in China]. (PubMed id 15793787)1, 4, 9 Liu J....Peng B. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2005)
    115. Carotid artery intima-media thickness and angiotensin-converting enzyme gene polymorphism in the offspring of parents with premature stroke. (PubMed id 15858957)1, 4, 9 Varda N.M....Gregoric A. (Acta Paediatr. 2005)
    116. Polymorphisms of the angiotensin converting enzyme and angiotensin II type 1 receptor genes and renal scarring in non-uropathic children with recurrent urinary tract infection. (PubMed id 16109085)1, 4, 9 Ece A....Budak T. (Nephrology (Carlton) 2005)
    117. Association of ACE polymorphisms with left ventricular hypertrophy. (PubMed id 16136003)1, 4, 9 Saeed M....Frossard P.M. (Neuro Endocrinol. Lett. 2005)
    118. Associations of baseline blood pressure levels and efficacy of Benazepril treatment with interaction of alpha-adducin and ACE gene polymorphisms in hypertensives. (PubMed id 15773232)1, 4, 9 Yu Y....Xu X. (Clin. Exp. Hypertens. 2005)
    119. Genetic variation at the ACE gene is associated with persistent microalbuminuria and severe nephropathy in type 1 diabetes: the DCCT/EDIC Genetics Study. (PubMed id 15793268)1, 4, 9 Boright A.P....Zinman B. (Diabetes 2005)
    120. ACE gene polymorphism, left ventricular geometry, and mortality in diabetic patients with end-stage renal disease. (PubMed id 15036826)1, 4, 9 Sakka Y....Iwamoto Y. (Diabetes Res. Clin. Pract. 2004)
    121. [Genetic polymorphism of the angiotensin I converting enzyme and morbi-mortality after myocardial infarction]. (PubMed id 15002705)1, 4, 9 Filippi-Codaccioni E....Hamon M. (Arch Mal Coeur Vaiss 2004)
    122. [Apolipoprotein E and angiotensin-converting enzyme gene polymorphisms as risk factors of coronary disease]. (PubMed id 15217762)1, 4, 9 Bennouar N....Benomar M. (Ann. Biol. Clin. (Paris) 2004)
    123. [Association between angiotensin converting enzyme gene, chymase gene and regression of left ventricular hypertrophy in patients treated with angiotensin converting enzyme inhibitors]. (PubMed id 15555355)1, 4, 9 He H....Hu Y.H. (Zhonghua Liu Xing Bing Xue Za Zhi 2004)
    124. Angiotensin-I converting enzyme gene polymorphism in Turkish type 2 diabetic patients. (PubMed id 15365253)1, 4, 9 Arzu Ergen H....Isbir T. (amp 2004)
    125. Association study of the I/D polymorphism and plasma angiotensin-converting enzyme (ACE) as risk factors for stent restenosis. (PubMed id 15101817)1, 4, 9 Ribichini F....Piazza A. (Clin. Sci. 2004)
    126. Association of angiotensin converting enzyme gene polymorphism with tachycardia cardiomyopathy. (PubMed id 14767579)1, 4, 9 Deshmukh P.M....Noti J.D. (Int. J. Mol. Med. 2004)
    127. [Polymorphic markers of GNB3 (C825T), AGTR1 (A1166C) and ACE (A2350G and I/D) genes in patients with arterial hypertension combined with diabetes mellitus type 2]. (PubMed id 15332573)1, 4, 9 Karpov R.S....Atroshenkov A.V. (Ter. Arkh. 2004)
    128. [The relationship between angiotensin-converting enzyme gene polymorphism and heart rate variability in cerebral stroke]. (PubMed id 15079800)1, 4, 9 Wang Y.M....Yang Z.C. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2004)
    129. Angiotensin converting enzyme genotype influences the response to the angiotensin II receptor antagonist losartan in patients with hypertension. (PubMed id 15080371)1, 4, 9 Nakamura Y....Yamada Y. (Hypertens. Res. 2004)
    130. Increased cardiovascular risk in long-term hemodialysis patients carrying deletion allele of ACE gene polymorphism. (PubMed id 15332219)1, 4, 9 Ishimitsu T....Matsuoka H. (Am. J. Kidney Dis. 2004)
    131. Lack of an association between angiotensin-converting enzyme gene insertion/deletion polymorphism and ischaemic stroke. (PubMed id 15007267)1, 4, 9 Karagiannis A....Zamboulis C. (Eur. Neurol. 2004)
    132. [Association of the complex of polymorphic markers of ACE genes, aldosteron synthetase and endothelial synthetase of nitric oxide with progression of chronic glomerulonephritis]. (PubMed id 15532370)1, 4, 9 Kamysheva E.S....Shilov E.M. (Ter. Arkh. 2004)
    133. Association between angiotensin converting enzyme gene polymorphism and coronary artery disease in individuals of the South-Eastern Anatolian population. (PubMed id 15033618)1, 4, 9 Nacak M....AynacioA9lu S. (Anadolu Kardiyol Derg 2004)
    134. DD genotype of ACE gene is a risk factor for intracerebral hemorrhage. (PubMed id 15277638)1, 2, 9 Slowik A.... Szczudlik A. (Neurology 2004)
    135. [The relationship between polymorphism of angiotensin converting enzyme gene and cough caused by angiotensin converting enzyme inhibitors]. (PubMed id 12901825)1, 4, 9 Yang S.M....Miao Y.D. (Zhonghua Jie He He Hu Xi Za Zhi 2003)
    136. Angiotensin-converting enzyme polymorphism gene and evolution of nephropathy to end-stage renal disease. (PubMed id 15012717)1, 4, 9 Ortiz M.A....Pou J.M. (Nephrology (Carlton) 2003)
    137. [I/D gene polymorphism of the angiotensin-converting enzyme and left ventricular hypertrophy. Response to converting enzyme inhibitors]. (PubMed id 12945221)1, 4, 9 Rugale C....Mimran A. (Arch Mal Coeur Vaiss 2003)
    138. [Polymorphic markers I/D and G7831A of angiotensin-I-converting enzyme gene and left ventricular hypertrophy in patients with essential hypertension]. (PubMed id 12891272)1, 4, 9 Brazhnik V.A....Sidorenko B.A. (Kardiologiia 2003)
    139. Angiotensin-converting enzyme and endothelial nitric oxide synthase polymorphisms in patients with atrial fibrillation. (PubMed id 12687832)1, 4, 9 Gensini F....Michelucci A. (Pacing Clin Electrophysiol 2003)
    140. Long-term renoprotective effects of losartan in diabetic nephropathy: interaction with ACE insertion/deletion genotype? (PubMed id 12716812)1, 4, 9 Andersen S....Parving H.H. (Diabetes Care 2003)
    141. No association between the angiotensin-converting-enzyme gene insertion/deletion polymorphism and the occurrence of macroangiopathy in patients with diabetes mellitus type 2. (PubMed id 12669270)1, 4, 9 Klemm T....Paschke R. (Horm. Metab. Res. 2003)
    142. [The role of polymorphic variants of renin-angiotensin system genes in the development of ischemic stroke in Moscow population]. (PubMed id 12830507)1, 4, 9 Skvortsov V.I....Shamalov N.A. (Zh Nevrol Psikhiatr Im S S Korsakova 2003)
    143. The influence of the ACE ( I/D) polymorphism on systemic and renal vascular responses to angiotensins in normotensive, normoalbuminuric Type 1 diabetes mellitus. (PubMed id 12856080)1, 4, 9 Luik P.T....Navis G.J. (Diabetologia 2003)
    144. Angiotensin-converting enzyme gene polymorphism and erythropoietin requirement. (PubMed id 12713075)1, 4, 9 Varagunam M....Yaqoob M.M. (Perit Dial Int 2003)
    145. Endothelin-1 and vasopressin plasma levels are not associated with the insertion/deletion polymorphism of the human angiotensin I-converting enzyme gene in patients with coronary artery disease. (PubMed id 12574792)1, 4, 9 Al-Fakhri N....Katz N. (J Hum Hypertens 2003)
    146. Coronary heart disease, hypertension, and angiotensinogen gene variants in Indian population. (PubMed id 12938141)1, 4, 9 Nair K.G....Dalal J.J. (J. Clin. Lab. Anal. 2003)
    147. Angiotensin-converting enzyme inhibitor withdrawal and ACE gene polymorphism. (PubMed id 14579936)1, 4, 9 Nonoguchi H....Tomita K. (Clin. Nephrol. 2003)
    148. [Genotypes of ACE gene in Kazakh and Uygur patients with ischemic heart disease]. (PubMed id 11855311)1, 4, 9 BaA-tasova N.B. and Rysmendiev A.Z.h. (Klin Med (Mosk) 2002)
    149. [Polymorphisms of ACE-1 and MTHFR genes and genetic susceptibility of ischemic stroke]. (PubMed id 12194796)1, 4, 9 Li C....Liu J. (Zhonghua Yi Xue Za Zhi 2002)
    150. ACE gene polymorphism and renal scarring in primary vesicoureteric reflux. (PubMed id 12478352)1, 4, 9 Haszon I....TA_ri S. (Pediatr. Nephrol. 2002)
    151. [Polymorphism of the angiotensin-converting enzyme gene in cardiovascular pathology]. (PubMed id 12442545)1, 4, 9 TseluA-ko V.I....Liashenko A.V. (Tsitol. Genet. 2002)
    152. Angiotensin-converting enzyme gene polymorphism and coronary heart disease in Turkish type 2 diabetic patients. (PubMed id 12222694)1, 4, 9 Araz M....Aktaran S. (Acta Cardiol 2002)
    153. High prevalence of polymorphisms of angiotensin-converting enzyme (I/D) and endothelial nitric oxide synthase (Glu298Asp) in patients with systemic sclerosis. (PubMed id 12015245)1, 4, 9 Fatini C....Matucci-Cerinic M. (Am. J. Med. 2002)
    154. The role of PC-1 and ACE genes in diabetic nephropathy in type 1 diabetic patients: evidence for a polygenic control of kidney disease progression. (PubMed id 12147786)1, 4, 9 De Cosmo S....Trischitta V. (Nephrol. Dial. Transplant. 2002)
    155. [ACE gene I/D-polymorphism and hereditary predisposition to myocardial infarction]. (PubMed id 12360613)1, 4, 9 Malygina N.A....Serova L.D. (Klin Med (Mosk) 2002)
    156. [Association of the renin-angiotensin system gene polymorphism with nephropathy in type II diabetes]. (PubMed id 12476891)1, 4, 9 BuraczyA8ska M....Ksiazek A. (Pol. Arch. Med. Wewn. 2002)
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    158. An interaction between systolic blood pressure and angiotensin-converting enzyme gene polymorphism on carotid atherosclerosis. (PubMed id 12484511)1, 4, 9 Kawamoto R....Miki T. (Hypertens. Res. 2002)
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    162. A chymase gene variant is associated with atherosclerosis in venous coronary artery bypass grafts. (PubMed id 11696688)1, 4, 9 Ortlepp J.R....Hoffmann R. (Coron. Artery Dis. 2001)
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    165. Polymorphisms of renin-angiotensin system genes in childhood IgA nephropathy. (PubMed id 11354780)1, 4, 9 Maruyama K....Yoshikawa N. (Pediatr. Nephrol. 2001)
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    167. Relationship of angiotensin converting enzyme genotype with serum triglyceride concentration in stroke patients. (PubMed id 11720769)1, 4, 9 del Ser T....CemillA!n C. (Neurosci. Lett. 2001)
    168. The ACE gene polymorphism and cough threshold for capsaicin after cilazapril usage. (PubMed id 11217909)1, 4, 9 Takahashi T....Kawakami Y. (Respir Med 2001)
    169. Analysis of the postulated interaction between the angiotensin II sub-type 1 receptor gene A1166C polymorphism and the insertion/deletion polymorphism of the angiotensin converting enzyme gene on risk of myocardial infarction. (PubMed id 11137090)1, 4, 9 Steeds R.P....Samani N.J. (Atherosclerosis 2001)
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    172. Left ventricular hypertrophy with exercise and ACE gene insertion/deletion polymorphism: a randomized controlled trial with losartan. (PubMed id 11208681)1, 4, 9 Myerson S.G....Pennell D.J. (Circulation 2001)
    173. Lack of association between angiotensin I-converting enzyme gene deletion polymorphism and cerebrovascular disease in Taiwanese. (PubMed id 11155741)1, 4, 9 Lin J.J....Harn H.J. (J. Formos. Med. Assoc. 2000)
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    175. Angiotensin II type-I receptor and ACE polymorphisms and risk of myocardial infarction in men and women. (PubMed id 11122322)1, 4, 9 Kee F....Evans A.E. (Eur. J. Clin. Invest. 2000)
    176. Detection of the association between a deletion polymorphism in the gene encoding angiotensin I-converting enzyme and advanced diabetic retinopathy. (PubMed id 11106834)1, 4, 9 Matsumoto A....Makino I. (Diabetes Res. Clin. Pract. 2000)
    177. Angiotensin II type 1 receptor gene A1166C polymorphism is associated with the increased risk of pregnancy-induced hypertension. (PubMed id 11208365)1, 4, 9 NaA8ogowska-GA8oA9nicka K....RzempoA8uch J. (Med. Sci. Monit. 2000)
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    179. The relationship of angiotensin-converting enzyme gene to essential hypertension and drug treatment in Chongqing. (PubMed id 11024215)1, 4, 9 Liu Q....Wang X. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2000)
    180. Angiotensin converting enzyme gene deletion allele is independently and strongly associated with coronary atherosclerosis and myocardial infarction. (PubMed id 8541160)1, 4, 9 Arbustini E....Specchia G. (Br Heart J 1995)
    181. Angiotensin-converting enzyme: zinc- and inhibitor-binding stoichiometries of the somatic and testis isozymes. (PubMed id 1649623)1, 2, 9 Ehlers M.R.W. and Riordan J.F. (Biochemistry 1991)
    182. Relationship between genetic polymorphisms of angiotensin-converting enzyme and methylenetetrahydrofolate reductase as risk factors for type 2 diabetes in Tunisian patients. (PubMed id 19857476)1, 4, 9 Mehri S....Hammami M. (Clin. Biochem. 2010)
    183. Angiotensin-converting enzyme gene polymorphism in overweight and obese Turkish patients with insulin resistance. (PubMed id 20070157)1, 4, 9 Akin F....Guclu A. (DNA Cell Biol. 2010)
    184. COC use, ACE/AGT gene polymorphisms, and risk of stroke. (PubMed id 20300047)1, 4, 9 Li Y....Shen H. (Pharmacogenet. Genomics 2010)
    185. Polymorphisms in NOS3, ACE and PAI-1 genes and risk of spontaneous recurrent miscarriage in the Gaza Strip. (PubMed id 20134171)1, 4, 9 Al Sallout R.J. and Sharif F.A. (Med Princ Pract 2010)
    186. Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants. (PubMed id 20161734)1, 4, 9 Bentley P....Sharma P. (PLoS ONE 2010)
    187. Effect of angiotensin-converting enzyme gene insertion/deletion polymorphism on steroid resistance in Egyptian children with idiopathic nephrotic syndrome. (PubMed id 20418353)1, 4, 9 Saber-Ayad M....Abdel-Shafy S. (J Renin Angiotensin Aldosterone Syst 2010)
    188. Migraine and coronary artery disease: an open study on the genetic polymorphism of the 5, 10 methylenetetrahydrofolate (MTHFR) and angiotensin I-converting enzyme (ACE) genes. (PubMed id 20518725)1, 4, 9 Pizza V....Capasso A. (Cent Nerv Syst Agents Med Chem 2010)
    189. DD genotype of angiotensin-converting enzyme in type 2 diabetes mellitus with renal disease in Mexican Mestizos. (PubMed id 19207872)1, 4, 9 Palomo-PiA+A^n S....Cruz M. (Nephrology (Carlton) 2009)
    190. Role of angiotensin converting enzyme, paraoxonase 1 55, 192 gene polymorphisms in syndrome X and coronary heart disease. (PubMed id 19579917)1, 4, 9 Sesal C....Sayar N. (Pak. J. Biol. Sci. 2009)
    191. [Complex analysis of genetic predisposition to ischemic stroke in Russians]. (PubMed id 19899640)1, 4, 9 Parfenov M.G....Favorova O.O. (Mol. Biol. (Mosk.) 2009)
    192. Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study. (PubMed id 19057513)1, 4, 9 SuonsyrjAo T....Hiltunen T.P. (Am. J. Hypertens. 2009)
    193. Elevated ACE activity is not associated with asthma, COPD, and COPD co-morbidity. (PubMed id 19423314)1, 4, 9 Lee J....Dahl M. (Respir Med 2009)
    194. Angiotensin-converting enzyme gene does not contribute to genetic susceptibility to systemic sclerosis in European Caucasians. (PubMed id 19132786)1, 4, 9 Wipff J....Allanore Y. (J. Rheumatol. 2009)
    195. ACE I/D polymorphism associated with abnormal atrial and atrioventricular conduction in lone atrial fibrillation and structural heart disease: implications for electrical remodeling. (PubMed id 19648063)1, 4, 9 Watanabe H....Darbar D. (Heart Rhythm 2009)
    196. Relationship between angiotensin-converting enzyme gene polymorphism and body composition, functional performance, and blood biomarkers in advanced cancer patients. (PubMed id 19258445)1, 4, 9 Vigano A....Morais J.A. (Clin. Cancer Res. 2009)
    197. Genetic variation in angiotensin-converting enzyme-related pathways associated with sudden cardiac arrest risk. (PubMed id 19716087)1, 4, 9 Sotoodehnia N....Siscovick D.S. (Heart Rhythm 2009)
    198. Genetic risk factors for arterial ischemic stroke in children: a possible MTHFR and eNOS gene-gene interplay? (PubMed id 19372095)1, 4, 9 Djordjevic V....Radojkovic D. (J. Child Neurol. 2009)
    199. Physical function is weakly associated with angiotensin-converting enzyme gene I/D polymorphism in elderly Japanese subjects. (PubMed id 19478476)1, 4, 9 Yoshihara A....Miyazaki H. (Gerontology 2009)
    200. Relationship between the angiotensin I-converting enzyme insertion/deletion (I/D) polymorphism and cardiovascular risk factors in healthy young Mexican women. (PubMed id 19371224)1, 4, 9 Vallejo M....Vargas-AlarcA^n G. (Genet Test Mol Biomarkers 2009)
    201. The relation of adiponectin and tumor necrosis factor alpha levels between endothelial nitric oxide synthase, angiotensin-converting enzyme, transforming growth factor beta, and tumor necrosis factor alpha gene polymorphism in adrenal incidentalomas. (PubMed id 19498318)1, 4, 9 Harman E....Yilmaz C. (J. Endocrinol. Invest. 2009)
    202. The insertion/deletion polymorphism of the angiotensin-converting enzyme gene is associated with progression, but not development, of albuminuria in Iranian patients with type 2 diabetes. (PubMed id 19502259)1, 4, 9 Nikzamir A....Reza J.Z. (J Renin Angiotensin Aldosterone Syst 2009)
    203. Interaction of angiotensin-converting enzyme and apolipoprotein E gene polymorphisms in ischemic stroke involving large-vessel disease. (PubMed id 18027070)1, 4, 9 Saidi S....Mahjoub T. (J. Thromb. Thrombolysis 2009)
    204. A synergistic association of ACE I/D and eNOS G894T gene variants with the progression of immunoglobulin A nephropathy - a pilot study. (PubMed id 19546528)1, 4, 9 RodrA-guez-PAcrez J.C....Torres A. (Am. J. Nephrol. 2009)
    205. AGT and ACE genes influence classic mitral valve prolapse predisposition in Marfan patients. (PubMed id 17379330)1, 4, 9 Fatini C....Pepe G. (Int. J. Cardiol. 2008)
    206. [Polymorphism of genes of the renin-angiotensin system ACE, AT1R, and AT2R in patients with pulmonary tuberculosis]. (PubMed id 18488444)1, 4, 9 Ogarkov O.B....Skvortsova R.G. (Mol. Gen. Mikrobiol. Virusol. 2008)
    207. ACE I/D polymorphism in Indian patients with hypertrophic cardiomyopathy and dilated cardiomyopathy. (PubMed id 18165925)1, 4, 9 Rai T.S....Khullar M. (Mol. Cell. Biochem. 2008)
    208. Association of insertion/deletion polymorphism of angiotensin-converting enzyme gene with essential hypertension and type 2 diabetes mellitus in Malaysian subjects. (PubMed id 19126661)1, 4, 9 Ramachandran V....Mohd Jas R. (J Renin Angiotensin Aldosterone Syst 2008)
    209. ACE gene polymorphism in Egyptian children with idiopathic nephrotic syndrome. (PubMed id 18792483)1, 4, 9 Fahmy M.E....Essawi M.L. (Bratisl Lek Listy 2008)
    210. Association of angiotensin-converting enzyme and endothelial Nitric Oxide synthase gene polymorphisms with vascular disease in ESRD patients in a Chinese population. (PubMed id 18629615)1, 4, 9 Tang F.Y....Xie X.W. (Mol. Cell. Biochem. 2008)
    211. Is the presence of retinopathy of practical value in defining cases of diabetic nephropathy in genetic association studies? The experience with the ACE insertion/deletion polymorphism in 53 studies comprising 17,791 subjects. (PubMed id 18523141)1, 4, 9 Ng D.P....Lim X.L. (Diabetes 2008)
    212. [Effect of angiotensin converting enzyme genotype on endothelial function in healthy subjects]. (PubMed id 18258525)1, 4, 9 Tanriverdi H....KiliAs M. (Anadolu Kardiyol Derg 2008)
    213. [Influence of angiotensin converting enzyme gene insertion/deletion polymorphism and beta3-adrenergic receptor gene Trp64Arg polymorphism on fetal growth and neonatal insulin sensitivity]. (PubMed id 19099777)1, 4, 9 Cui Y.P....Ye H.M. (Zhonghua Er Ke Za Zhi 2008)
    214. Angiotensin-1 converting enzyme I/D gene polymorphism: scenario in Malaysia. (PubMed id 19058590)1, 4, 9 Jayapalan J.J....Chan S.P. (Southeast Asian J. Trop. Med. Public Health 2008)
    215. Relationships between blood pressure, polymorphism of angiotensin-converting enzyme (ACE), body composition and biochemical characteristics in elderly Slovaks. (PubMed id 18712159)1, 4, 9 SivA!kovA! D....BlazA-cek P. ( Bericht über die biologisch-anthropologische Literatur 2008)
    216. Influence of angiotensin I-converting enzyme polymorphism on development of post-transplant erythrocytosis in renal graft recipients. (PubMed id 18339134)1, 4, 9 Kedzierska K....Ciechanowski K. (Clin Transplant 2008)
    217. Angiotensin-converting enzyme polymorphisms and risk of spontaneous deep intracranial hemorrhage in Taiwan. (PubMed id 18754764)1, 4, 9 Chen C.M....Lee-Chen G.J. (Eur. J. Neurol. 2008)
    218. Angiotensin-converting enzyme insertion/deletion polymorphism and the risk of ischemic stroke in a South Indian population. (PubMed id 18586276)1, 4, 9 Munshi A....Jyothy A. (J. Neurol. Sci. 2008)
    219. The effects of angiotensin-converting enzyme gene polymorphism on the progression of immunoglobulin A nephropathy in Malaysian patients. (PubMed id 19037561)1, 4, 9 Draman C.R....Shamsul A.S. (Singapore Med J 2008)
    220. High dose Losartan and ACE gene polymorphism in IgA nephritis. (PubMed id 19319668)1, 4, 9 Woo K.T....Wong K.S. (Genomic Med 2008)
    221. Polymorphisms in two genes, IL-1B and ACE, are associated with erythropoietin resistance in Korean patients on maintenance hemodialysis. (PubMed id 18446054)1, 4, 9 Jeong K.H....Moon J.Y. (amp 2008)
    222. Angiotensinogen gene T235 variant: a marker for the development of persistent microalbuminuria in children and adolescents with type 1 diabetes mellitus. (PubMed id 18413222)1, 4, 9 Gallego P.H....Choong C.S. (J. Diabetes Complicat. 2008)
    223. Angiotensin-converting enzyme gene polymorphism is correlated to diabetic retinopathy: a meta-analysis. (PubMed id 18280446)1, 4, 9 Wiwanitkit V. (J. Diabetes Complicat. 2008)
    224. Lack of association between endothelial nitric oxide synthase gene polymorphisms, microalbuminuria and endothelial dysfunction in hypertensive men. (PubMed id 17563560)1, 4, 9 Dell'Omo G....Pedrinelli R. (J. Hypertens. 2007)
    225. Absence of an interaction between the angiotensin-converting enzyme insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensive patients: the Genetics of Hypertension-Associated Treatment (GenHAT) study. (PubMed id 17174637)1, 4, 9 Maitland-van der Zee A.H....Eckfeldt J.H. (Am. Heart J. 2007)
    226. Polymorphisms of the renin-angiotensin system genes predict progression of subclinical coronary atherosclerosis. (PubMed id 17327458)1, 4, 9 Kretowski A....Rewers M. (Diabetes 2007)
    227. Polymorphism modulates symptomatic response to antiarrhythmic drug therapy in patients with lone atrial fibrillation. (PubMed id 17556195)1, 4, 9 Darbar D....Roden D.M. (Heart Rhythm 2007)
    228. Evaluation of atrial and brain natriuretic polypeptides in association with angiotensin-converting enzyme gene polymorphism in Japanese non-diabetic hemodialysis patients. (PubMed id 17454955)1, 4, 9 Nakao K....Doi T. (Scand. J. Urol. Nephrol. 2007)
    229. Angiotensin-converting enzyme insertion/deletion (ACE I/D) and angiotensin II type 1 receptor (AT1R) gene polymorphism and its association with preeclampsia in Chinese women. (PubMed id 17710578)1, 4, 9 Li H....Wang L. (Hypertens Pregnancy 2007)
    230. ACE gene polymorphism in peripheral vascular disease. (PubMed id 17611909)1, 4, 9 BaA9ar Y....OzkAPk E. (Horm. Metab. Res. 2007)
    231. Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: a meta-analysis. (PubMed id 17171228)1, 4, 9 Banerjee I....Ganesh S. (J. Hum. Genet. 2007)
    232. [I/D polymorphism of angiotensin I converting enzyme gene and arterial hypertension in patients with type 2 diabetes mellitus]. (PubMed id 17682668)1, 4, 9 Moleda P....Adler G. (Pol. Merkur. Lekarski 2007)
    233. Effect of angiotensin-converting enzyme insertion/deletion genotype on collagen type I synthesis and degradation in patients with atrial fibrillation and arterial hypertension. (PubMed id 17927479)1, 4, 9 Tziakas D.N....Boudoulas H. (Expert Opin Pharmacother 2007)
    234. Angiotensin-converting enzyme I/D and alpha-adducin Gly460Trp polymorphisms: from angiotensin-converting enzyme activity to cardiovascular outcome. (PubMed id 17452507)1, 4, 9 Li Y....Staessen J.A. (Hypertension 2007)
    235. The role of angiotensin-converting enzyme gene insertion/deletion polymorphism for blood pressure regulation in areca nut chewers. (PubMed id 17585864)1, 4, 9 Chung F.M....Lee Y.J. (Transl Res 2007)
    236. The relationship between angiotensin-converting enzyme (insertion/deletion) gene polymorphism and left ventricular remodeling in acute myocardial infarction. (PubMed id 17429286)1, 4, 9 Ulgen M.S....Toprak N. (Coron. Artery Dis. 2007)
    237. Angiotensin-converting enzyme gene polymorphism and stroke in type 2 diabetic patients in Taiwan. (PubMed id 17537156)1, 4, 9 Tseng C.H....Cheng J.C. (Eur. J. Clin. Invest. 2007)
    238. Relationship of angiotensin-converting enzyme gene polymorphism with nephropathy associated with Type 2 diabetes mellitus in Asian Indians. (PubMed id 17616353)1, 4, 9 Movva S....Hasan Q. (J. Diabetes Complicat. 2007)
    239. Association between polymorphisms of ACE, B2AR, ANP and ENOS and cardiovascular diseases: a community-based study in the Matsu area. (PubMed id 17243909)1, 4, 9 Hu C.J....Chang C.J. (Clin. Chem. Lab. Med. 2007)
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    241. Association of ACE gene polymorphism with genetic susceptibility to systemic lupus erythematosus in a Chinese population: a family-based association study. (PubMed id 17937470)1, 4, 9 Xu J....Ding C. (J. Rheumatol. 2007)
    242. Modification of the coronary artery disease risk associated with the presence of traditional risk factors by insertion/deletion polymorphism of the ACE gene. (PubMed id 18294050)1, 4, 9 Niemiec P....Wita K. (Genet. Test. 2007)
    243. Renal function dependent association of AGTR1 polymorphism (A1166C) and electrocardiographic left-ventricular hypertrophy. (PubMed id 17903694)1, 4, 9 Smilde T.D....Navis G. (Am. J. Hypertens. 2007)
    244. Study of candidate genes affecting the progression of renal disease in autosomal dominant polycystic kidney disease type 1. (PubMed id 17303584)1, 4, 9 TazA^n-Vega B....Torra R. (Nephrol. Dial. Transplant. 2007)
    245. Angiotensin I-converting enzyme insertion-related genotypes and allele are associated with higher susceptibility of endometriosis and leiomyoma. (PubMed id 17186537)1, 4, 9 Hsieh Y.Y....Lin C.S. (Mol. Reprod. Dev. 2007)
    246. Effects of angiotensin-converting enzyme gene polymorphism and serum vitamin D levels on ambulatory blood pressure measurement and left ventricular mass in Turkish hypertensive population. (PubMed id 17625392)1, 4, 9 Kulah E....Dursun A. (Blood Press Monit 2007)
    247. Pharmacogenetic interactions of three candidate gene polymorphisms with ACE-inhibitors or beta-blockers and the risk of atherosclerosis. (PubMed id 17298481)1, 4, 9 Schelleman H....Stricker B.H. (Br J Clin Pharmacol 2007)
    248. Sequence variants of ACE, AGT, AT1R, and PAI-1 as genetic risk factors for vascular dementia. (PubMed id 16603315)1, 4, 9 Kim Y....Lee C. (Neurosci. Lett. 2006)
    249. [Meta-analysis of association of deletion allele of angiotensin-converting enzyme gene with coronary heart disease in China]. (PubMed id 17166429)1, 4, 9 Jiang X....Liao Y.H. (Zhonghua Yu Fang Yi Xue Za Zhi 2006)
    250. A common variant in the ACE gene is associated with peripheral neuropathy in women with type 2 diabetes mellitus. (PubMed id 16949519)1, 4, 9 Stephens J.W....Hurel S.J. (J. Diabetes Complicat. 2006)
    251. ACE gene polymorphism in Turkish children with nephrotic syndrome. (PubMed id 16825089)1, 4, 9 Celik U.S....Matyar S. (Ren Fail 2006)
    252. ACE gene polymorphisms influence t-PA-induced brain vessel reopening following ischemic stroke. (PubMed id 16442232)1, 4, 9 FernA!ndez-Cadenas I....Montaner J. (Neurosci. Lett. 2006)
    253. Renal haemodynamics are not related to genotypes in offspring of parents with essential hypertension. (PubMed id 17083073)1, 4, 9 Skov K....Mulvany M.J. (J Renin Angiotensin Aldosterone Syst 2006)
    254. Association analysis of genes in the renin-angiotensin system with subclinical cardiovascular disease in families with Type 2 diabetes mellitus: the Diabetes Heart Study. (PubMed id 16492203)1, 4, 9 Burdon K.P....Bowden D.W. (Diabet. Med. 2006)
    255. Insertion/deletion polymorphism of angiotensin converting enzyme gene in Kawasaki disease. (PubMed id 16614502)1, 4, 9 Shim Y.H....Hong Y.M. (J. Korean Med. Sci. 2006)
    256. Restenosis after percutaneous coronary intervention is associated with the angiotensin-II type-1 receptor 1166A/C polymorphism but not with polymorphisms of angiotensin-converting enzyme, angiotensin-II receptor, angiotensinogen or heme oxygenase-1. (PubMed id 16609364)1, 4, 9 Wijpkema J.S....Tio R.A. (Pharmacogenet. Genomics 2006)
    257. Angiotensin-I-converting enzyme (ACE) insertion/deletion polymorphism in Mexican patients with coronary artery disease. Association with the disease but not with lipid levels. (PubMed id 16764852)1, 4, 9 Vargas-AlarcA^n G....Posadas-Romero C. (Exp. Mol. Pathol. 2006)
    258. [The incidence of some angiotensin-1 converting enzyme gene alleles in patients with coronary heart disease]. (PubMed id 16512390)1, 4, 9 Istrati V.F....Kalin G.V. (Klin Med (Mosk) 2006)
    259. [The relationship between ACE I/D polymorphism and HDL cholesterol]. (PubMed id 17168204)1, 4, 9 You C.H....Kim J.Y. (J Prev Med Public Health 2006)
    260. ACE gene insertion/deletion polymorphism modulates capillary permeability in hypertension. (PubMed id 16889537)1, 4, 9 Dell'omo G....Pedrinelli R. (Clin. Sci. 2006)
    261. Hydrochlorothiazide efficacy and polymorphisms in ACE, ADD1 and GNB3 in healthy, male volunteers. (PubMed id 16450155)1, 4, 9 Vormfelde S.V....BrockmAPller J. (Eur. J. Clin. Pharmacol. 2006)
    262. Insertion/deletion polymorphism on ACE gene is associated with endothelial dysfunction in young patients with hypertension. (PubMed id 16981142)1, 4, 9 Penesova A....Krizanova O. (Horm. Metab. Res. 2006)
    263. Angiotensin I-converting enzyme gene polymorphism modifies the smoking-cancer association: the Hisayama Study. (PubMed id 16679861)1, 4, 9 Arima H....Iida M. (Eur. J. Cancer Prev. 2006)
    264. Angiotensin-converting enzyme gene insertion/deletion polymorphism in Korean patients with systemic sclerosis. (PubMed id 16614523)1, 4, 9 Joung C.I....Yoo D.H. (J. Korean Med. Sci. 2006)
    265. Angiotensin converting enzyme gene polymorphisms do not predict the course of idiopathic nephrotic syndrome in Swiss children. (PubMed id 17199794)1, 4, 9 Sasse B....Neuhaus T.J. (Nephrology (Carlton) 2006)
    266. Angiotensin-converting enzyme gene polymorphism is correlated to the progression of disease in patients with IgA nephropathy: a meta-analysis. (PubMed id 17162429)1, 4, 9 Wiwanitkit V. (Ren Fail 2006)
    267. Angiotensin-converting enzyme gene polymorphism in children with idiopathic nephrotic syndrome. (PubMed id 16645262)1, 4, 9 Tsai I.J....Hsieh F.J. (Am. J. Nephrol. 2006)
    268. The effect of ACE gene polymorphisms on Doppler blood flow parameters of carotid and brachial arteries in patients with myocardial infarction. (PubMed id 17235107)1, 4, 9 Bilici A....Alan B. (Angiology 2006)
    269. Association between angiotensin-converting enzyme gene polymorphisms and QT duration in a multiethnic population in Hawaii. (PubMed id 16769256)1, 4, 9 Grandinetti A....Low P.A. (amp 2006)
    270. Effects of angiotensin II type 1 receptor gene polymorphisms on insulin resistance in a Japanese general population: the Tanno-Sobetsu study. (PubMed id 17378368)1, 4, 9 Akasaka H....Ogihara T. (Hypertens. Res. 2006)
    271. Genetic susceptibility to atrial fibrillation in patients with congestive heart failure. (PubMed id 16818212)1, 4, 9 Bedi M....Schwartzman D. (Heart Rhythm 2006)
    272. Angiotensin converting enzyme insertion/deletion polymorphism does not influence postcardiac transplantation hypertension onset or progression. (PubMed id 15797740)1, 4, 9 Fildes J.E....Yonan N. (J. Heart Lung Transplant. 2005)
    273. Effects of angiotensin-converting enzyme polymorphism on aortic elastic parameters in athletes. (PubMed id 16088128)1, 4, 9 Tanriverdi H....KiliAs M. (Cardiology 2005)
    274. Angiotensin-converting enzyme genotype is not associated with exercise capacity or the training effect of cardiac rehabilitation in patients after acute myocardial infarction. (PubMed id 16247204)1, 4, 9 Iwanaga Y....Goto Y. (Circ. J. 2005)
    275. Angiotensin-converting enzyme (ACE) haplotypes and cyclosporine A (CsA) response: a model of the complex relationship between ACE quantitative trait locus and pathological phenotypes. (PubMed id 16002416)1, 4, 9 Catarsi P....Ghiggeri G.M. (Hum. Mol. Genet. 2005)
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    277. Frequency of angiotensin-converting enzyme gene polymorphism in Turkish type 2 diabetic patients. (PubMed id 16178979)1, 4, 9 Degirmenci I....Demirustu C. (Int. J. Clin. Pract. 2005)
    278. Influence of angiotensin-converting enzyme polymorphism gene, IGF-1, and other factors in the response rate of hematocrit to enalapril treatment in patients with posttransplant erythrocytosis. (PubMed id 15848608)1, 4, 9 Jimeno L....Minguela A. (Transplant. Proc. 2005)
    279. ACE gene polymorphism in children with nephrotic syndrome in the Indonesian population. (PubMed id 16421456)1, 4, 9 Sasongko T.H....Nishio H. (Kobe J Med Sci 2005)
    280. Low renin-angiotensin system activity gene polymorphism and dysplasia associated with posterior urethral valves. (PubMed id 16006956)1, 4, 9 Peruzzi L....Coppo R. (J. Urol. 2005)
    281. [Plasminogen activator inhibitor-1 (PAI-1) 4G/5G and angiotensin converting enzyme (ACE) I/D gene polymorphisms and fibrinolytic activity in patients with essential hypertension and dyslipidemia]. (PubMed id 16130596)1, 4, 9 Jastrzebska M....Naruszewicz M. (Pol. Arch. Med. Wewn. 2005)
    282. Lack of association between common polymorphisms in genes of the renin-angiotensin system and mortality after myocardial infarction. (PubMed id 15785027)1, 4, 9 Andrikopoulos G.K....Mattu R. (Cardiology 2005)
    283. Renin-angiotensin polymorphisms and QTc interval prolongation in end-stage renal disease. (PubMed id 16105049)1, 4, 9 Raizada V....Spalding C.T. (Kidney Int. 2005)
    284. [Do left ventricular mass, diameters and long-axis systolic function differ according to angiotensin converting enzyme genotypes?]. (PubMed id 16140645)1, 4, 9 DursunoA9lu D....KiliAs M. (Anadolu Kardiyol Derg 2005)
    285. [Pharmacogenetics of angiotensin system in non diabetic nephropathy]. (PubMed id 16231503)1, 4, 9 Coto E....Campistol J.M. (Nefrologia 2005)
    286. Influence of angiotensin-converting enzyme I/D gene polymorphism on the right ventricular myocardial performance index in patients with a first acute anterior myocardial infarction. (PubMed id 15671615)1, 4, 9 Ozturk O....Toprak N. (Circ. J. 2005)
    287. The relation between obesity, abdominal fat deposit and the angiotensin-converting enzyme gene I/D polymorphism and its association with coronary heart disease. (PubMed id 15520830)1, 4, 9 Riera-Fortuny C....HernA!ndez-Mijares A. (Int J Obes (Lond) 2005)
    288. Novel approach of molecular genetic understanding of iridology: relationship between iris constitution and angiotensin converting enzyme gene polymorphism. (PubMed id 16047566)1, 4, 9 Um J.Y....Kim H.M. (Am. J. Chin. Med. 2005)
    289. [I/D-polymorphism of ACE gene, morphofunctional heart condition and blood pressure 24-h profile in young men with arterial hypertension]. (PubMed id 16281482)1, 4, 9 Bagmet A.D. and Shestopal N.S. (Ter. Arkh. 2005)
    290. Angiotensin-converting enzyme and endothelial constitutive nitric oxide synthase polymorphisms in Turkish renal transplant population and possible influence on renal artery atherosclerosis and graft survival. (PubMed id 16213264)1, 4, 9 Ozdemir F.N....Haberal M. (Transplant. Proc. 2005)
    291. Polymorphisms of the renin-angiotensin system genes in Brazilian patients with lupus nephropathy. (PubMed id 15934435)1, 4, 9 Sprovieri S.R. and Sens Y.A. (Lupus 2005)
    292. [Angiotensin converting enzyme, NO-synthase, and endothelin-1 genes and left ventricular hypertrophy in natives of Yakutia with hypertensive disease]. (PubMed id 15699938)1, 4, 9 Minushkina L.O....Sidorenko B.A. (Kardiologiia 2005)
    293. [The role of polymorphic markers of vasoactive hormones genes in clinical characteristics of chronic glomerulonephritis]. (PubMed id 16078594)1, 4, 9 Kamyshova E.S....Shvetsov M.I.u. (Ter. Arkh. 2005)
    294. Polymorphisms of the renin-angiotensin system and the severity of fibrosis in chronic hepatitis C virus infection. (PubMed id 16108768)1, 4, 9 Forrest E.H....Mills P.R. (J. Viral Hepat. 2005)
    295. Angiotensin-converting enzyme i/d polymorphism in patients with malignant hypertension. (PubMed id 15655381)1, 4, 9 Espinel E....Bachs A.G. (J Clin Hypertens (Greenwich) 2005)
    296. ACE gene insertion/deletion polymorphism in childhood idiopathic nephrotic syndrome. (PubMed id 16208534)1, 4, 9 Serdaroglu E....Bak M. (Pediatr. Nephrol. 2005)
    297. Renovascular disease: effect of ACE gene deletion polymorphism and endovascular revascularization. (PubMed id 14718831)1, 4, 9 Pizzolo F....Olivieri O. (J. Vasc. Surg. 2004)
    298. Angiotensin-converting enzyme gene polymorphism significantly affects renal posttransplantation erythrocytosis. (PubMed id 15013333)1, 4, 9 MicozkadioA9lu H....Haberal M. (Transplant. Proc. 2004)
    299. Angiotensin-converting enzyme and angiotensin type 2 receptor gene genotype distributions in Italian children with congenital uropathies. (PubMed id 15470205)1, 4, 9 Rigoli L....Salpietro C.D. (Pediatr. Res. 2004)
    300. ACE I/D gene polymorphism in primary FSGS and steroid-sensitive nephrotic syndrome. (PubMed id 14986085)1, 4, 9 Oktem F....Ispir T. (Pediatr. Nephrol. 2004)
    301. [Study on relationship between the polymorphism of angiotensin converting enzyme gene and blood stasis syndrome in patients with coronary heart disease]. (PubMed id 15495818)1, 4, 9 Mao Y.L....Hu Z. (Zhongguo Zhong Xi Yi Jie He Za Zhi 2004)
    302. ACE I allele and eNOS G allele crosstalk may have a role in chronic obstructive pulmonary disease. (PubMed id 15498534)1, 4, 9 Ahsan A....Pasha M.A. (Clin. Biochem. 2004)
    303. Genetic influences on blood pressure within the Stanislas Cohort. (PubMed id 15076187)1, 4, 9 Sass C....Visvikis S. (J. Hypertens. 2004)
    304. Carotid remodeling of hypertensive subjects and polymorphism of the angiotensin-converting enzyme gene. (PubMed id 14733772)1, 4, 9 Li S.J....Zhou S.M. (Chin. Med. J. 2004)
    305. Polymorphism of the ACE gene is associated with extent and severity of coronary disease. (PubMed id 15732661)1, 4, 9 MendonAsa I....dos Reis R.P. (Rev Port Cardiol 2004)
    306. Polymorphism of renin-angiotensin system genes in IgA nephropathy. (PubMed id 15504143)1, 4, 9 Woo K.T....Wong K.S. (Nephrology (Carlton) 2004)
    307. Genetic polymorphisms of angiotensin system genes in congenital diaphragmatic hernia associated with persistent pulmonary hypertension. (PubMed id 15017542)1, 4, 9 Solari V. and Puri P. (J. Pediatr. Surg. 2004)
    308. Renin angiotensin aldosterone system and ACE I/D gene polymorphism in high-altitude pulmonary edema. (PubMed id 15558999)1, 4, 9 Kumar R....Gupta V. (Aviat Space Environ Med 2004)
    309. Renin-angiotensin system gene polymorphisms: its impact on IgAN and its progression to end-stage renal failure among Chinese in Singapore. (PubMed id 15153745)1, 4, 9 Lau Y.K....Wong K.S. (Nephron Physiol 2004)
    310. Angiotensin converting enzyme genotype and chronic allograft nephropathy in protocol biopsies. (PubMed id 15284309)1, 4, 9 Hueso M....SerA^n D. (J. Am. Soc. Nephrol. 2004)
    311. Genetic polymorphism of the renin-angiotensin system on the development of primary vesicoureteral reflux. (PubMed id 14764974)1, 4, 9 Yim H.E....Kim S.K. (Am. J. Nephrol. 2004)
    312. Angiotensin-converting enzyme (insertion/deletion) and endothelial nitric oxide synthase polymorphisms in patients with systemic lupus erythematosus. (PubMed id 15338496)1, 4, 9 Douglas G....Gilkeson G. (J. Rheumatol. 2004)
    313. Angiotensin-converting enzyme gene polymorphism and risk of myocardial infarction in Colombia. (PubMed id 15277998)1, 4, 9 Bautista L.E....Arenas I.A. (Med. Sci. Monit. 2004)
    314. GNB3 gene C825T and ACE gene I/D polymorphisms in essential hypertension in a Kazakh genetic isolate. (PubMed id 15042113)1, 4, 9 Wang X....Wen H. (J Hum Hypertens 2004)
    315. Association of peripheral and central arterial wave reflections with the CYP11B2 -344C allele and sodium excretion. (PubMed id 15614025)1, 4, 9 Wojciechowska W....Kawecka-Jaszcz K. (J. Hypertens. 2004)
    316. Progression of left ventricular hypertrophy and the angiotensin-converting enzyme gene polymorphism in hypertrophic cardiomyopathy. (PubMed id 15314809)1, 4, 9 Doolan G....Semsarian C. (Int. J. Cardiol. 2004)
    317. Renin-angiotensin system and associated gene polymorphisms in myocardial infarction in young South African Indians. (PubMed id 14997233)1, 4, 9 Ranjith N....Naidoo D.P. (Cardiovasc J S Afr 2004)
    318. [Angiotensin-converting enzyme gene and the brachial artery endothelial dysfunction in type 2 diabetes without angiopathy]. (PubMed id 15300633)1, 4, 9 Xiang G.D....Wu Y.H. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2004)
    319. Interaction and relationship between angiotensin converting enzyme gene and environmental factors predisposing to essential hypertension in Mongolian population of China. (PubMed id 15386943)1, 4, 9 Xu Q....Qiu C.C. (Biomed. Environ. Sci. 2004)
    320. The functional angiotensin converting enzyme gene I/D polymorphism does not alter susceptibility to chronic pancreatitis. (PubMed id 15536282)1, 4, 9 Oruc N....Whitcomb D.C. (JOP 2004)
    321. The role of angiotensin-converting enzyme and apolipoprotein-E gene polymorphisms on lipid compositions in newborn infants with intrauterine growth restriction. (PubMed id 15223114)1, 4, 9 Akisu M....Kultursay N. (Early Hum. Dev. 2004)
    322. The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin-converting enzyme inhibitor. (PubMed id 15226090)1, 4, 9 Jiang S....Xu X. (Thromb. Res. 2004)
    323. ACE genotype and cognitive decline in an African-Caribbean population. (PubMed id 15465635)1, 4, 9 Stewart R....Mann A. (Neurobiol. Aging 2004)
    324. [Effect of ACE gene polymorphism on carbohydrate metabolism, on oxidative stress and on end-organ damage in type-2 diabetes mellitus]. (PubMed id 15156690)1, 4, 9 MolnA!r G.A....Wittmann I. (Orv Hetil 2004)
    325. Possible synergic effect of angiotensin-I converting enzyme gene insertion/deletion polymorphism and angiotensin-II type-1 receptor 1166A/C gene polymorphism on ischemic heart disease in patients with Kawasaki disease. (PubMed id 15295089)1, 4, 9 Fukazawa R....Ogawa S. (Pediatr. Res. 2004)
    326. [Angiotensin-converting enzyme gene polymorphism in patients with obstructive sleep apnea]. (PubMed id 15526842)1, 4, 9 Rubinsztajn R....Chazan R. (Pol. Arch. Med. Wewn. 2004)
    327. Renin-angiotensin system polymorphisms in Taiwanese primary vesicoureteral reflux. (PubMed id 15045574)1, 4, 9 Liu K.P....Lee-Chen G.J. (Pediatr. Nephrol. 2004)
    328. Acute effects of nifedipine administration in pulmonary haemodynamics and oxygen delivery during exercise in patients with chronic obstructive pulmonary disease: implication of the angiotensin-converting enzyme gene polymorphisms. (PubMed id 15233837)1, 4, 9 Kanazawa H....Yoshikawa J. (Clin Physiol Funct Imaging 2004)
    329. [ACE gene polymorphisms associated with serum ACE activity in the Henan Hans of China]. (PubMed id 15651670)1, 4, 9 Kong X.D. and Zhang S.Z. (Yi Chuan Xue Bao 2004)
    330. [Association of polymorphisms in the angiotensin system genes with obstructive sleep apnea-hypopnea syndrome]. (PubMed id 15387996)1, 4, 9 Zhang L.Q....Lin Y.P. (Zhonghua Jie He He Hu Xi Za Zhi 2004)
    331. Insertion/deletion plasminogen activator inhibitor 1 and insertion/deletion angiotensin-converting enzyme gene polymorphisms in diabetic retinopathy in type 2 diabetes. (PubMed id 12660488)1, 4, 9 Globocnik-Petrovic M....Petrovic D. (Ophthalmologica 2003)
    332. Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen. (PubMed id 12871600)1, 4, 9 Adams G.T....Kutlar A. (BMC Med. Genet. 2003)
    333. [Effect of ACE gene polymorphism on left ventricular function in patients with type 2 diabetes]. (PubMed id 12728591)1, 4, 9 Valocik G....KovA!cs L. (Vnitr Lek 2003)
    334. Polymorphism of angiotensin-converting enzyme gene and BMI in obese Korean women. (PubMed id 12559614)1, 4, 9 Um J.Y....Kim H.M. ( international journal of clinical chemistry 2003)
    335. Angiotensin-converting enzyme-gene polymorphism is associated with collagen I synthesis and QT dispersion in essential hypertension. (PubMed id 12714874)1, 4, 9 Takahashi T....Takata M. (J. Hypertens. 2003)
    336. Crystal structure of the human angiotensin-converting enzyme- lisinopril complex. (PubMed id 12540854)1, 2, 9 Natesh R.... Acharya K.R. (Nature 2003)
    337. Influence of ACE (I/D) and G460W polymorphism of alpha-adducin in autosomal dominant polycystic kidney disease. (PubMed id 13679477)1, 4, 9 Persu A....Devuyst O. (Nephrol. Dial. Transplant. 2003)
    338. Renin-angiotensin system gene polymorphisms: assessment of the risk of coronary heart disease. (PubMed id 14502296)1, 4, 9 BuraczyA8ska M....Ksiazek A. (Kardiol Pol 2003)
    339. [Association of the G7831A polymorphism of the ACE gene with myocardial ischemia in the Moscow population]. (PubMed id 12624945)1, 4, 9 Nikitin A.G....Nosikov V.V. (Mol. Biol. (Mosk.) 2003)
    340. Interaction between ACE and ADD1 gene polymorphisms in the progression of IgA nephropathy in Japanese patients. (PubMed id 12885793)1, 4, 9 Narita I....Gejyo F. (Hypertension 2003)
    341. The ACE/DD genotype is associated with the extent of exercise-induced left ventricular growth in endurance athletes. (PubMed id 12906984)1, 4, 9 HernA!ndez D....GonzA!lez A. (J. Am. Coll. Cardiol. 2003)
    342. [Arterial hypertension in glomerulonephritis]. (PubMed id 14974362)1, 4, 9 Oko A....Czekalski S. (Pol. Merkur. Lekarski 2003)
    343. ACE gene I/D and NOS3 G894T polymorphisms and response to sildenafil in men with erectile dysfunction. (PubMed id 12837457)1, 4, 9 Eisenhardt A....Siffert W. (Urology 2003)
    344. Interaction between angiotensin-converting enzyme genotype and glycaemic control influences lipoprotein levels in type 2 diabetes mellitus. (PubMed id 12658909)1, 4, 9 TkA!c I....Kalina I. (Wien. Klin. Wochenschr. 2003)
    345. No effect of angiotensin-converting enzyme gene polymorphism on disease progression and left ventricular hypertrophy in autosomal dominant polycystic kidney disease. (PubMed id 14600431)1, 4, 9 Ecder T....Schrier R.W. (Am. J. Nephrol. 2003)
    346. Association of high-altitude systemic hypertension with the deletion allele-of the angiotensin-converting enzyme (ACE) gene. (PubMed id 12743791)1, 4, 9 Kumar R....Brahamchari S.K. (Int J Biometeorol 2003)
    347. Relationship between ACE gene polymorphism and ischemic chronic heart failure in Turkish population. (PubMed id 12911874)1, 4, 9 Akbulut T....Yesilcimen K. (Eur. J. Med. Res. 2003)
    348. Study of the polymorphism of angiotensinogen, anigiotensin-converting enzyme and angiotensin receptor in type II diabetes with end-stage renal disease in Taiwan. (PubMed id 12728975)1, 4, 9 Chang H.R....Wu M.Y. (J Chin Med Assoc 2003)
    349. ACE and alpha-adducin polymorphism as markers of individual response to diuretic therapy. (PubMed id 12623934)1, 4, 9 Sciarrone M.T....Cusi D. (Hypertension 2003)
    350. Influence of the alpha-adducin and ACE gene polymorphism on the progression of autosomal-dominant polycystic kidney disease. (PubMed id 12697976)1, 4, 9 Merta M....Kmentova D. (amp 2003)
    351. [Polymorphism of the promotor region of the angiotensinogen gene and the gene for angiotensin I-converting enzyme in arterial hypertension and myocardial ischemia of the Kazakh ethnic groups]. (PubMed id 12669427)1, 4, 9 AA-tkhozhina N.A. and Liudvikova E.K. (Genetika 2003)
    352. Angiotensin-converting enzyme genotype modulates pulmonary function and exercise capacity in treated patients with congestive stable heart failure. (PubMed id 12356632)1, 4, 9 Abraham M.R....Johnson B.D. (Circulation 2002)
    353. Angiotensin-converting enzyme insertion/deletion polymorphism does not influence the restenosis rate after coronary stent implantation. (PubMed id 11893827)1, 4, 9 Ferrari M....Figulla H.R. (Cardiology 2002)
    354. Gene polymorphisms of the renin-angiotensin-aldosterone system and essential arterial hypertension in childhood. (PubMed id 12597535)1, 4, 9 Petrovic D....Peterlin B. (Folia Biol. (Krakow) 2002)
    355. Angiotensin-converting enzyme insertion/deletion polymorphism and polyneuropathy in type 2 diabetes without macroalbuminuria. (PubMed id 12449516)1, 4, 9 Ito H....Kurabayashi M. (J. Int. Med. Res. 2002)
    356. ACE gene polymorphism and renal scar in children with acute pyelonephritis. (PubMed id 12172760)1, 4, 9 Cho S.J. and Lee S.J. (Pediatr. Nephrol. 2002)
    357. The role of ACE gene polymorphism in rapidity of progression of focal segmental glomerulosclerosis. (PubMed id 12571380)1, 4, 9 Dixit M....Glicklich D. (J Postgrad Med 2002)
    358. Angiotensin-converting enzyme gene insertion/deletion polymorphism in Polish patients with myocardial infarction. (PubMed id 12898814)1, 4, 9 Sobstyl J....Hanzlik J. (Ann Univ Mariae Curie Sklodowska Med 2002)
    359. Angiotensin converting enzyme gene polymorphism and glomerular filtration rate changes in type 2 diabetic patients. (PubMed id 12166538)1, 4, 9 Araz M....Aynacioglu S. (Int. J. Clin. Pract. 2002)
    360. Relation of Apo E and ACE genes to cognitive performance in chronic alcoholic patients. (PubMed id 12006218)1, 4, 9 BartrAcs-Faz D....JunquAc C. (Addict Biol 2002)
    361. [Association of insertion/deletion polymorphism in angiotensin-converting enzyme gene with hypertensive type 2 diabetes mellitus]. (PubMed id 12297438)1, 4, 9 Zhou L....Gao F. (Di Yi Jun Yi Da Xue Xue Bao 2002)
    362. Angiotensin-converting enzyme genotype and outcome in pediatric IgA nephropathy. (PubMed id 12172761)1, 4, 9 Santos N.M....Wyatt R.J. (Pediatr. Nephrol. 2002)
    363. Angiotensin converting enzyme insertion/deletion genotype is associated with leukoaraiosis in lacunar syndromes. (PubMed id 11861692)1, 4, 9 Hassan A....Bamford J.M. (J. Neurol. Neurosurg. Psychiatr. 2002)
    364. Lack of association between angiotensin-converting enzyme gene polymorphism and peripheral vascular disease in type 2 diabetic patients in Taiwan. (PubMed id 12419932)1, 4, 9 Tseng C.H. and Tseng C.P. (Circ. J. 2002)
    365. Genetic polymorphisms of renin-angiotensin system and progression of interstitial nephritis. (PubMed id 12898858)1, 4, 9 BuraczyA8ska M....Ksiazek A. (Ann Univ Mariae Curie Sklodowska Med 2002)
    366. The effect of angiotensin converting enzyme gene polymorphism on chronic allograft dysfunction in living donor renal transplant recipients. (PubMed id 12010139)1, 4, 9 Yildiz A....Erginel-Unaltuna N. (Clin Transplant 2002)
    367. Relationship between polymorphisms in the renin-angiotensin system and nephropathy in type 2 diabetic patients. (PubMed id 11938025)1, 4, 9 Fradin S....Reznik Y. (amp 2002)
    368. No association between high-altitude tolerance and the ACE I/D gene polymorphism. (PubMed id 12471298)1, 4, 9 Dehnert C....BAortsch P. (Med Sci Sports Exerc 2002)
    369. Renin-angiotensin-aldosterone system (RAAS) gene polymorphism as a risk factor of coronary in-stent restenosis. (PubMed id 12205735)1, 4, 9 Ryu S.K....Cho S.Y. (Yonsei Med. J. 2002)
    370. Angiotensin-converting enzyme gene polymorphism is associated with vulnerability to alcoholic cardiomyopathy. (PubMed id 12204015)1, 4, 9 FernA!ndez-SolA J....Urbano-MA!rquez A. (Ann. Intern. Med. 2002)
    371. Exercise-induced changes in insulin action are associated with ACE gene polymorphisms in older adults. (PubMed id 12388790)1, 4, 9 Dengel D.R....Supiano M.A. (Physiol. Genomics 2002)
    372. The estimation of gametic disequilibrium between DNA markers in candidate genes for coronary artery disease (CAD) and the associations of gene complexes with risk factors for CAD. (PubMed id 11507973)1, 4, 9 Spiridonova M.G....Karpov R.S. (Int J Circumpolar Health 2001)
    373. Both alleles of the M235T polymorphism of the angiotensinogen gene can be a risk factor for myocardial infarction. (PubMed id 11531970)1, 4, 9 FernA!ndez-ArcA!s N....Reyes-Engel A. (Clin. Genet. 2001)
    374. Significance of ACE genotypes and medical treatments in childhood focal glomerulosclerosis. (PubMed id 11474225)1, 4, 9 Hori C....Mayumi M. (Nephron 2001)
    375. [Polymorphism of the angiotensin-converting enzyme gene in patients with coronary heart disease from Moscow population]. (PubMed id 11421129)1, 4, 9 Shadrina M.I....Limborskaia S.A. (Genetika 2001)
    376. Increased risk for ischaemic events is related to combined RAS polymorphism. (PubMed id 11250978)1, 4, 9 van Geel P.P....van Gilst W.H. (Heart 2001)
    377. Loss of renal function following bone marrow transplantation: an analysis of angiotensin converting enzyme D/I polymorphism and other clinical risk factors. (PubMed id 11313676)1, 4, 9 Juckett M.B....Klein J. (Bone Marrow Transplant. 2001)
    378. The insertion/deletion polymorphism of the ACE gene is related to insulin sensitivity in overweight women. (PubMed id 11522714)1, 4, 9 Ryan A.S....Ferrell R.E. (Diabetes Care 2001)
    379. Angiotensin converting enzyme gene polymorphism predicts blood pressure response to angiotensin II receptor type 1 antagonist treatment in hypertensive patients. (PubMed id 11593098)1, 4, 9 Kurland L....Lind L. (J. Hypertens. 2001)
    380. Association of the DD genotype and development of Japanese type 2 diabetic nephropathy. (PubMed id 11770799)1, 4, 9 Gohda T....Tomino Y. (Clin. Nephrol. 2001)
    381. Relationship between angiotensin-converting enzyme gene polymorphism and insulin resistance in never-treated hypertensive patients. (PubMed id 11231997)1, 4, 9 Perticone F....Mattioli P.L. (J. Clin. Endocrinol. Metab. 2001)
    382. [A study of relationship between oral contraceptives and gene polymorphism and types of stroke]. (PubMed id 11718065)1, 4, 9 Chen J....Zhou J. (Zhonghua Liu Xing Bing Xue Za Zhi 2001)
    383. Interaction between apolipoprotein-E and angiotensin-converting enzyme genotype in Alzheimer's disease. (PubMed id 11501342)1, 4, 9 Isbir T....Eker E. (Am J Alzheimers Dis Other Demen 2001)
    384. The platelet Pl(A2) and angiotensin-converting enzyme (ACE) D allele polymorphisms and the risk of recurrent events after acute myocardial infarction. (PubMed id 11545752)1, 4, 9 Bray P.F....Braunwald E. (Am. J. Cardiol. 2001)
    385. Prognostic value of angiotensin-I converting enzyme I/D polymorphism for nephropathy in type 1 diabetes mellitus: a prospective study. (PubMed id 11181802)1, 4, 9 Hadjadj S....Marre M. (J. Am. Soc. Nephrol. 2001)
    386. Angiotensin converting enzyme in patients with sleep apnoea syndrome: plasma activity and gene polymorphisms. (PubMed id 11401071)1, 4, 9 BarcelA^ A....Agusti A.G. (Eur. Respir. J. 2001)
    387. [Association between insertion-deletion polymorphism of the angiotensin-converting enzyme gene and development of angiopathies in patients with non-insulin dependent diabetes mellitus from the Chuvash Republic]. (PubMed id 11234416)1, 4, 9 Miloserdova O.V....Limborskaia S.A. (Genetika 2001)
    388. Association of angiotensin converting enzyme and plasminogen activator inhibitor-1 promoter gene polymorphisms with features of the insulin resistance syndrome in patients with premature coronary heart disease. (PubMed id 11427204)1, 4, 9 Viitanen L....Laakso M. (Atherosclerosis 2001)
    389. ACE genotype and endothelium-dependent vasodilation of conduit arteries and forearm microcirculation in humans. (PubMed id 11498459)1, 4, 9 Arcaro G....Bonadonna R.C. (Arterioscler. Thromb. Vasc. Biol. 2001)
    390. Candidate gene polymorphisms in cardiovascular disease: a comparative study of frequencies between a French and an Italian population. (PubMed id 11341749)1, 4, 9 Pallaud C....Visvikis S. (Clin. Chem. Lab. Med. 2001)
    391. Angiotensin-converting enzyme gene polymorphism, lipids, and apolipoproteins in menopausal women on hormone replacement therapy. (PubMed id 12398019)1, 4, 9 Cubrilo-Turek M....DurakoviA8 Z. (Acta Med Croatica 2001)
    392. Genetic influences on lipid metabolism trait variability within the Stanislas Cohort. (PubMed id 11714857)1, 4, 9 Pallaud C....Visvikis S. (J. Lipid Res. 2001)
    393. Polymorphism of the angiotensin-converting enzyme gene in patients with cerebral infarction in Koreans. (PubMed id 11859923)1, 4, 9 Um J.Y....Kim J.J. (J. Mol. Neurosci. 2001)
    394. The angiotensin I converting enzyme gene as a susceptibility factor for dementia. (PubMed id 11402126)1, 4, 9 Richard F....Helbecque N. (Neurology 2001)
    395. Angiotensin converting enzyme gene insertion/deletion polymorphism in idiopathic nephrotic syndrome in Kuwaiti Arab children. (PubMed id 11487079)1, 4, 9 Al-Eisa A....Srivastva B.S. (Scand. J. Urol. Nephrol. 2001)
    396. Angiotensin-converting enzyme gene polymorphism and microvascular complications in Turkish type 2 diabetic patients. (PubMed id 11640993)1, 4, 9 Araz M....SA1krA1 Aynacioglu A. (Diabetes Res. Clin. Pract. 2001)
    397. Angiotensin-converting enzyme gene polymorphism in a cohort of coronary angiography patients. (PubMed id 11257269)1, 4, 9 Eichner J.E....Schechter E. (Atherosclerosis 2001)
    398. [ACE gene polymorphism in patients with ischemic brain disease]. (PubMed id 12830537)1, 4, 9 Skvortsova V.I....Kondrat'eva E.A. (Zh Nevrol Psikhiatr Im S S Korsakova 2001)
    399. Low potentiality of angiotensin-converting enzyme gene insertion/deletion polymorphism as a useful predictive marker for carotid atherogenesis in a large general population of a Japanese city: the Suita study. (PubMed id 11387483)1, 4, 9 Mannami T....Ogata J. ( a journal of cerebral circulation 2001)
    400. Ace D/I polymorphism and incidence of post-PTCA restenosis: a prospective, angiography-based evaluation. (PubMed id 11244007)1, 4, 9 Zee R.Y....Fernandez-Cruz A. (Hypertension 2001)
    401. Is there a role of angiotensin-converting enzyme gene polymorphism in the failure of arteriovenous femoral shunts for hemodialysis? (PubMed id 11525534)1, 4, 9 Isbir C.S....Cobanoglu A. (Ann Vasc Surg 2001)
    402. Contribution of gene polymorphisms in the renin-angiotensin system to macroangiopathy in patients with diabetic nephropathy. (PubMed id 11431175)1, 4, 9 Wong T.Y....Li P.K. (Am. J. Kidney Dis. 2001)
    403. Relations between ACE gene and ecNOS gene polymorphisms and resistive index in type 2 diabetic patients with nephropathy. (PubMed id 11522715)1, 4, 9 Taniwaki H....Nishizawa Y. (Diabetes Care 2001)
    404. ACE gene polymorphism and IgA nephropathy: an ethnically homogeneous study and a meta-analysis. (PubMed id 11473656)1, 4, 9 Schena F.P....Gesualdo L. (Kidney Int. 2001)
    405. Angiotensin-converting enzyme gene polymorphism in patients with systemic lupus. (PubMed id 11505631)1, 4, 9 Prkacin I....Mrzljak A. (Acta Med Croatica 2001)
    406. Ace gene I/D polymorphism and sarcoidosis pulmonary disease severity. (PubMed id 11463587)1, 4, 9 McGrath D.S....Dolek V. (Am. J. Respir. Crit. Care Med. 2001)
    407. The DD genotype of angiotensin converting enzyme polymorphism is a risk factor for coronary artery disease and coronary stent restenosis in Japanese patients. (PubMed id 11665795)1, 4, 9 Taniguchi I....Mochizuki S. (Jpn. Circ. J. 2001)
    408. Angiotensin gene polymorphism as a determinant of posttransplantation renal dysfunction and hypertension. (PubMed id 11544438)1, 4, 9 Abdi R....Milford E.L. (Transplantation 2001)
    409. Renal outcome and vascular morbidity in systemic lupus erythematosus (SLE): lack of association with the angiotensin-converting enzyme gene polymorphism. (PubMed id 11071585)1, 4, 9 Molad Y....Shohat M. (Semin. Arthritis Rheum. 2000)
    410. alpha-adducin and angiotensin I-converting enzyme polymorphisms in essential hypertension. (PubMed id 11116113)1, 4, 9 Clark C.J....Connell J.M. (Hypertension 2000)
    411. Renin-angiotensin system polymorphisms and coronary events in familial hypercholesterolemia. (PubMed id 11082147)1, 4, 9 Wierzbicki A.S....Crook M.A. (Hypertension 2000)
    412. ACE/DD genotype is associated with hemostasis balance disturbances reflecting hypercoagulability and endothelial dysfunction in patients with untreated hypertension. (PubMed id 11054622)1, 4, 9 Makris T.K....Kyriakidis M.K. (Am. Heart J. 2000)
    413. [The relationship between angiotensin converting enzyme gene polymorphism and risk factors for coronary heart disease]. (PubMed id 11860787)1, 4, 9 Shan J....Fu G. (Zhonghua Liu Xing Bing Xue Za Zhi 2000)
    414. Relation between the insertion/deletion polymorphism of the angiotensin I converting enzyme gene and restenosis after coronary stenting. (PubMed id 11155292)1, 4, 9 GA1rlek A....Oral D. (J Cardiovasc Risk 2000)
    415. [Polymorphism of genes coding for angiotensin I converting enzyme and methylenetetrahydrofolate reductase in patients with ischemic heart disease]. (PubMed id 11712321)1, 4, 9 Goracy I. (Ann Acad Med Stetin 2000)
    416. Lack of association of ACE/angiotensinogen genotype with renal function in autosomal dominant polycystic kidney disease. (PubMed id 11142763)1, 4, 9 Saggar-Malik A.K....Jeffery S. (Genet. Test. 2000)
    417. Polymorphism of angiotensin-converting enzyme gene and genetic susceptibility to asthma with familial aggregation. (PubMed id 12899394)1, 4, 9 Gao J....Bai Y. (Chin. Med. Sci. J. 2000)
    418. An Angiotensin I converting enzyme polymorphism is associated with clinical phenotype when using differentiation-syndrome to categorize korean bronchial asthma patients. (PubMed id 19525331)1, 4 Jung S.K....Kim J. (Evid Based Complement Alternat Med 2011)
    419. Renin-angiotensin system associated with risk of upper GI mucosal injury induced by low dose aspirin: renin angiotensin system genes' polymorphism. (PubMed id 20824505)1, 4 Shiotani A....Haruma K. (Dig. Dis. Sci. 2011)
    420. Effects of age, genes, and pulse pressure on executive functions in healthy adults. (PubMed id 19559505)1, 4 Raz N....Land S. (Neurobiol. Aging 2011)
    421. Human metabolic individuality in biomedical and pharmaceutical research. (PubMed id 21886157)1, 4 Suhre K....Gieger C. (Nature 2011)
    422. Angiotensin converting enzyme I/D, angiotensinogen M235T and AT1-R A/C1166 gene polymorphisms in patients with acromegaly. (PubMed id 20361261)1, 4 Turgut S....Turgut G. (Mol. Biol. Rep. 2011)
    423. No replication of genetic association between candidate polymorphisms and Alzheimer's disease. (PubMed id 19889475)1, 4 Cousin E....Campion D. (Neurobiol. Aging 2011)
    424. Angiotensin converting enzyme DD genotype is associated with development of rheumatic heart disease in Egyptian children. (PubMed id 19847428)1, 4 Morsy M.M....Ismail M.A. (Rheumatol. Int. 2011)
    425. Meta-analysis of association between insertion/deletion polymorphism of the Angiotensin I-converting enzyme gene and venous thromboembolism. (PubMed id 19833623)1, 4 Hsiao F.C. and Hsu L.A. (Clin. Appl. Thromb. Hemost. 2011)
    426. Genetic cardiovascular risk factors and age-related macular degeneration. (PubMed id 19860767)1, 4 Haas P....Binder S. (Acta Ophthalmol 2011)
    427. Angiotensin-converting enzyme gene variant and its levels: risk factors for myocardial infarction in a South Indian population. (PubMed id 20730398)1, 4 Pulla Reddy B....Jyothy A. (Singapore Med J 2010)
    428. Cytokine polymorphisms and Alzheimer disease: possible associations. (PubMed id 20213229)1, 4 Ribizzi G....Megna M. (Neurol. Sci. 2010)
    429. Genetical, histological, and clinical characteristics of IgA-negative mesangioproliferative glomerulopathy. (PubMed id 19937361)1, 4 Owada K....Watanabe T. (Clin. Exp. Nephrol. 2010)
    430. A multilocus candidate approach identifies ACE and HIF1A as susceptibility genes for cellulite. (PubMed id 20059631)1, 4 Emanuele E....Geroldi D. (J Eur Acad Dermatol Venereol 2010)
    431. Prevalence of angiotensin-converting enzyme, methylenetetrahydrofolate reductase, Factor V Leiden, prothrombin and apolipoprotein E gene polymorphisms in Morocco. (PubMed id 20687780)1, 4 They-They T.P....Nadifi S. (Ann. Hum. Biol. 2010)
    432. Polymorphisms of the angiotensin converting enzyme gene in Iranian Azeri Turkish women with unexplained recurrent pregnancy loss. (PubMed id 20722577)1, 4 Bagheri M....Nanbaksh F. (Hum Fertil (Camb) 2010)
    433. Lack of association of ACE gene I/D polymorphism with obstructive sleep apnea syndrome in Turkish patients. (PubMed id 20449805)1, 4 Yakut T....Karadag M. (Genet. Mol. Res. 2010)
    434. Lack of association between antipsychotic-induced extrapyramidal symptoms and polymorphisms in dopamine metabolism and transport genes. (PubMed id 19892410)1, 4 GassA^ P....Lafuente A. (Psychiatry Res 2010)
    435. Investigation of ACE, ACE2 and AGTR1 genes for association with nephropathy in Type 1 diabetes mellitus. (PubMed id 20854388)1, 4 Currie D....Maxwell A.P. (Diabet. Med. 2010)
    436. [Correlation of metabolic syndrome clinical signs and genetic determinants at children with obese]. (PubMed id 21033077)1, 4 Shcherbakova M.I.u....Pronina L.A. (amp 2010)
    437. Potential genetic risk factors in angiotensin-converting enzyme-inhibitor-induced angio-oedema. (PubMed id 20233181)1, 4 Bas M....Kojda G. (Br J Clin Pharmacol 2010)
    438. The I/D polymorphism of the ACE1 gene is not associated with ischaemic stroke in Spanish individuals. (PubMed id 20402757)1, 4 Domingues-Montanari S....Montaner J. (Eur. J. Neurol. 2010)
    439. Interactions among related genes of renin-angiotensin system associated with type 2 diabetes. (PubMed id 20592051)1, 4 Yang J.K....Ma Y.H. (Diabetes Care 2010)
    440. Association between angiotensin-converting enzyme insertion/deletion genetic polymorphism and hypertension in a sample of Lebanese patients. (PubMed id 20939740)1, 4 Akra-Ismail M....Zgheib N.K. (Genet Test Mol Biomarkers 2010)
    441. Alteration of resting brain function by genetic variation in angiotensin converting enzyme in amnestic-type mild cognitive impairment of Chinese Han. (PubMed id 20085788)1, 4 Zhang Z....Zhang Z. (Behav. Brain Res. 2010)
    442. Impact of renin-angiotensin system polymorphisms on development of systolic dysfunction in hypertrophic cardiomyopathy. Evidence from a study of genotyped patients. (PubMed id 20975235)1, 4 Funada A....Yamagishi M. (Circ. J. 2010)
    443. Functional polymorphisms in genes of the Angiotensin and Serotonin systems and risk of hypertrophic cardiomyopathy: AT1R as a potential modifier. (PubMed id 20594303)1, 4 Coto E....Alvarez V. (J Transl Med 2010)
    444. Angiotensin II receptor type 1 1166 A/C and angiotensin converting enzyme I/D gene polymorphisms in a Dutch sarcoidosis cohort. (PubMed id 21319597)1, 4 Kruit A....van den Bosch J.M. (Sarcoidosis Vasc Diffuse Lung Dis 2010)
    445. Angiotensin-converting enzyme D/I and plasminogen activator inhibitor-1 4G/5G gene polymorphisms are associated with increased risk of spontaneous abortions in polycystic ovarian syndrome. (PubMed id 19636212)1, 4 Sun L....Guan Y. (J. Endocrinol. Invest. 2010)
    446. Association of angiotensin converting enzyme gene insertion/deletion polymorphism with lung cancer in Turkey. (PubMed id 20303010)1, 4 Nacak M....AynacioA9lu A.S. (Cancer Genet. Cytogenet. 2010)
    447. Association of the genetic polymorphisms of the ACE gene and the eNOS gene with lupus nephropathy in northern Chinese population. (PubMed id 20540812)1, 4 Li X....Jin X. (BMC Med. Genet. 2010)
    448. MTHFR 677C-&gt;T and ACE D/I polymorphisms and migraine attack frequency in women. (PubMed id 19673907)1, 4 SchA1rks M....Kurth T. (Cephalalgia 2010)
    449. Insertion/Deletion polymorphism of Angiotensin-converting enzyme as a risk factor for chronic allograft nephropathy. (PubMed id 20692468)1, 4 Fedor R....TA^th A. (Transplant. Proc. 2010)
    450. Analyses of shared genetic factors between asthma and obesity in children. (PubMed id 20816195)1, 4 MelAcn E....Lasky-Su J. (J. Allergy Clin. Immunol. 2010)
    451. Treatment of obese adolescents: the influence of periodization models and ACE genotype. (PubMed id 19680237)1, 4 Foschini D....DAcmaso A.R. (Obesity (Silver Spring) 2010)
    452. Common genetic variation, residential proximity to traffic exposure, and left ventricular mass: the multi-ethnic study of atherosclerosis. (PubMed id 20308035)1, 4 Van Hee V.C....Kaufman J.D. (Environ. Health Perspect. 2010)
    453. Association of angiotensinogen gene M235T and angiotensin-converting enzyme gene I/D polymorphisms with essential hypertension in Han Chinese population: a meta-analysis. (PubMed id 20087216)1, 4 Ji L.D....Xu J. (J. Hypertens. 2010)
    454. Genetic effects on carotid intima-media thickness: systematic assessment and meta-analyses of candidate gene polymorphisms studied in more than 5000 subjects. (PubMed id 20160191)1, 4 Paternoster L....Sudlow C.L. (Circ Cardiovasc Genet 2010)
    455. The angiotensin converting enzyme D allele is an independent risk factor for early onset coronary artery disease. (PubMed id 20655894)1, 4 Vaisi-Raygani A....Pourmotabbed T. (Clin. Biochem. 2010)
    456. Polymorphisms of the angiotensin converting enzyme gene in early-onset and late-onset pre-eclampsia. (PubMed id 20044877)1, 4 Uma R....Murphy D.J. (amp 2010)
    457. Gene polymorphisms against DNA damage induced by hydrogen peroxide in leukocytes of healthy humans through comet assay: a quasi-experimental study. (PubMed id 20444272)1, 4 Miranda-Vilela A.L....Klautau-GuimarALes M.N. (Environ Health 2010)
    458. Demonstrating the pharmacogenetic effects of angiotensin-converting enzyme inhibitors on long-term prognosis of diastolic heart failure. (PubMed id 19752885)1, 4 Wu C.K....Chiang F.T. (Pharmacogenomics J. 2010)
    459. Angiotensin-converting enzyme gene polymorphism and risk of insulin resistance in PCOS. (PubMed id 20138007)1, 4 Celik O....Ozerol E. (Reprod. Biomed. Online 2010)
    460. Renin-angiotensin system-related gene polymorphisms are associated with risk of atrial fibrillation. (PubMed id 20826259)1, 4 Xiao P....Yin Y. (Am. Heart J. 2010)
    461. Association of ACE and FACTOR VII gene variability with the risk of coronary heart disease in north Indian population. (PubMed id 20364300)1, 4 Sobti R.C....Talwar K.K. (Mol. Cell. Biochem. 2010)
    462. A prospective case-control study analyzes 12 thrombophilic gene mutations in Turkish couples with recurrent pregnancy loss. (PubMed id 19906129)1, 4 Yenicesu G.I....Kocak N. (Am. J. Reprod. Immunol. 2010)
    463. Does the polygenic profile determine the potential for becoming a world-class athlete? Insights from the sport of rowing. (PubMed id 19422651)1, 4 Santiago C....Lucia A. (amp 2010)
    464. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    465. Angiotensin-converting enzyme insertion/deletion gene polymorphism in a Tunisian healthy and acute myocardial infarction population. (PubMed id 20059382)1, 4 Mehri S....Ben Arab S. (Genet Test Mol Biomarkers 2010)
    466. Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615)1, 4 RuaA+o G....Wu A.H. (Pharmacogenomics 2010)
    467. No interactions between genetic polymorphisms and stressful life events on outcome of antidepressant treatment. (PubMed id 20022223)1, 4 Bukh J.D....Kessing L.V. (Eur Neuropsychopharmacol 2010)
    468. Thrombophilic risk factors in the pathogenesis of non-arteritic anterior ischemic optic neuropathy patients. (PubMed id 20162297)1, 4 Felekis T....Asproudis I. (Graefes Arch. Clin. Exp. Ophthalmol. 2010)
    469. Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study. (PubMed id 20413850)1, 4 Laumet G....Lambert J.C. (J. Alzheimers Dis. 2010)
    470. Renin-angiotensin-aldosterone system gene polymorphisms in coronary artery bypass graft surgery patients. (PubMed id 20223792)1, 4 Ragia G....Manolopoulos V.G. (J Renin Angiotensin Aldosterone Syst 2010)
    471. Is there an association between angiotensin converting enzyme (ACE) genotypes and abdominal aortic aneurysm? (PubMed id 20655774)1, 4 Obukofe B....Bown M.J. (Eur J Vasc Endovasc Surg 2010)
    472. Influence of polymorphisms in candidate genes on early vascular alterations in obese children. (PubMed id 20142115)1, 4 Tounian A....Tounian P. (Arch Cardiovasc Dis 2010)
    473. Polymorphisms of the angiotensin converting enzyme gene in relation to intrauterine growth restriction. (PubMed id 20524904)1, 4 Uma R....Murphy D.J. (Acta Obstet Gynecol Scand 2010)
    474. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    475. Identification of type 2 diabetes-associated combination of SNPs using support vector machine. (PubMed id 20416077)1, 4 Ban H.J....Park K.J. (BMC Genet. 2010)
    476. Polymorphisms of the TNF-alpha and ACE genes, and renal scarring in infants with urinary tract infection. (PubMed id 20022049)1, 4 Savvidou A....Galanakis E. (J. Urol. 2010)
    477. Angiotensin-converting enzyme insertion/deletion polymorphism associated with acute respiratory distress syndrome among caucasians. (PubMed id 20515555)1, 4 Hu Z....Liao X. (J. Int. Med. Res. 2010)
    478. Insertion/deletion polymorphism and serum activity of the angiotensin-converting enzyme in Turkish patients with obstructive sleep apnea syndrome. (PubMed id 20182789)1, 4 Ogus C....Gumuslu S. (Biochem. Genet. 2010)
    479. Angiotensinogen polymorphisms and acquired atrial fibrillation in Chinese. (PubMed id 19932491)1, 4 Wang Q.S....Wang X.F. (J Electrocardiol 2010)
    480. Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study. (PubMed id 20577119)1, 4 Irvin M.R....Arnett D.K. (J. Hypertens. 2010)
    481. Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture. (PubMed id 20173430)1, 4 Herlyn P....Gradl G. (Clin J Pain 2010)
    482. Are &quot;functionally related polymorphisms&quot; of renin-angiotensin-aldosterone system gene polymorphisms associated with hypertension? (PubMed id 20525211)1, 4 Hahntow I.N....Michel M.C. (BMC Cardiovasc Disord 2010)
    483. Genetic associations with mountain sickness in Han and Tibetan residents at the Qinghai-Tibetan Plateau. (PubMed id 20570668)1, 4 Buroker N.E....Chen S.H. ( international journal of clinical chemistry 2010)
    484. The COPD genetic association compendium: a comprehensive online database of COPD genetic associations. (PubMed id 19933216)1, 4 Castaldi P.J....Trikalinos T.A. (Hum. Mol. Genet. 2010)
    485. Angiotensin I-converting enzyme insertion/deletion polymorphism and increased risk of gall bladder cancer in women. (PubMed id 20438364)1, 4 Srivastava K....Mittal B. (DNA Cell Biol. 2010)
    486. Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease. (PubMed id 20346360)1, 4 Roberts K.E....Fallon M.B. (Gastroenterology 2010)
    487. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1, 4 He C....Hunter D.J. (Hum. Genet. 2010)
    488. Angiotensin converting enzyme gene insertion/deletion polymorphism in patients with polycystic ovary syndrome. (PubMed id 20170341)1, 4 Karabulut A....Turgut G. (Gynecol. Endocrinol. 2010)
    489. Evaluation of gene polymorphisms in exercise-induced oxidative stress and damage. (PubMed id 20109103)1, 4 Akimoto A.K....Klautau-GuimarALes M.d.e. .N. (Free Radic. Res. 2010)
    490. Angiotensin-converting enzyme gene I/D genotype affected metoprolol-induced reduction in 24-hour average heart rate. (PubMed id 20819590)1, 4 Liu L.W....Li Y.S. (Chin. Med. J. 2010)
    491. A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). (PubMed id 20673868)1, 4 Romero R....Menon R. (Am. J. Obstet. Gynecol. 2010)
    492. Intermediate phenotypes identify divergent pathways to Alzheimer's disease. (PubMed id 20574532)1, 4 Shulman J.M....De Jager P.L. (PLoS ONE 2010)
    493. Genetic association study of the GNB3 C825T, the ACE I/D and the eNOS G894T polymorphisms and the risk to develop erectile dysfunction in a German ED population. (PubMed id 20629643)1, 4 Eisenhardt A....Sperling H. (Andrologia 2010)
    494. Effects of prolonged exercise on left ventricular mechanical synchrony in long-distance runners: importance of previous exposure to endurance races. (PubMed id 20688470)1, 4 SahlAcn A....Braunschweig F. (J Am Soc Echocardiogr 2010)
    495. Renin angiotensin system polymorphisms in patients with metabolic syndrome (MetS). (PubMed id 20816596)1, 4 Procopciuc L.M....Zdrenghea D. (Eur. J. Intern. Med. 2010)
    496. The relationship between angiotensin converting enzyme gene I/D polymorphism and QT dispersion in patients with hypertrophic cardiomyopathy. (PubMed id 20478904)1, 4 Kaya C.T....Erol C. (J Renin Angiotensin Aldosterone Syst 2010)
    497. Associations between genetic variants in the ACE, AGT, AGTR1 and AGTR2 genes and renal function in the Multi-ethnic Study of Atherosclerosis. (PubMed id 20606419)1, 4 Campbell C.Y....Post W.S. (Am. J. Nephrol. 2010)
    498. Lack of association of genetic polymorphisms of angiotensin-converting enzyme gene I/D and glutathione-S-transferase enzyme T1 and M1 with retinopathy of prematures. (PubMed id 21038299)1, 4 Yildiz M....Ozmen A. (Genet. Mol. Res. 2010)
    499. A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor. (PubMed id 20066004)1, 4 Chung C.M....Pan W.H. (Pharmacogenomics J. 2010)
    500. Vascular at-risk genotypes and disease severity in Lebanese sickle cell disease patients. (PubMed id 20425806)1, 4 Farra C....Oberkanins C. (Am. J. Hematol. 2010)
    501. Angiotensin-converting enzyme polymorphism in schizophrenia, bipolar disorders, and their first-degree relatives. (PubMed id 20010451)1, 4 Kucukali C.I....Kara I. (Psychiatr. Genet. 2010)
    502. MTHFR 677C&gt;T and ACE D/I polymorphisms in migraine: a systematic review and meta-analysis. (PubMed id 19925624)1, 4 SchA1rks M....Kurth T. (Headache 2010)
    503. Association of circulating angiotensin converting enzyme activity with respiratory muscle function in infants. (PubMed id 20462446)1, 4 Dimitriou G....Mantagos S. (Respir. Res. 2010)
    504. Common genetic variations of the renin-angiotensin-aldosterone system and response to acute angiotensin I-converting enzyme inhibition in essential hypertension. (PubMed id 20027122)1, 4 Hannila-Handelberg T....Hiltunen T.P. (J. Hypertens. 2010)
    505. Angiotensin-converting enzyme gene polymorphism is associated with proliferative diabetic retinopathy: a meta-analysis. (PubMed id 19865794)1, 4 Zhou J.B. and Yang J.K. (Acta Diabetol 2010)
    506. The angiotensin-converting enzyme insertion/deletion polymorphism modifies the clinical outcome in patients with Pompe disease. (PubMed id 20308911)1, 4 de Filippi P....Danesino C. (Genet. Med. 2010)
    507. Pharmacogenetic interactions between Angiotensin-converting enzyme insertion/deletion polymorphism and response to cibenzoline in patients with hypertrophic obstructive cardiomyopathy. (PubMed id 20179607)1, 4 Ogimoto A....Higaki J. (J. Cardiovasc. Pharmacol. 2010)
    508. Genetic risk factors and the anti-atherosclerotic effect of pioglitazone on carotid atherosclerosis of subjects with type 2 diabetes--a retrospective study. (PubMed id 20134102)1, 4 Saitou M....Yamasaki Y. (J. Atheroscler. Thromb. 2010)
    509. Association of ACE I/D polymorphism in Tunisian patients with dilated cardiomyopathy. (PubMed id 20478902)1, 4 Mahjoub S....Ben Arab S. (J Renin Angiotensin Aldosterone Syst 2010)
    510. ACE DD genotype is unfavorable to Korean short-term muscle power athletes. (PubMed id 20029740)1, 4 Kim C.H....Kim C. (Int J Sports Med 2010)
    511. Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program. (PubMed id 20682687)1, 4 Jablonski K.A....Florez J.C. (Diabetes 2010)
    512. No evidence of an association between two genes, EDN1 and ACE, and childhood-onset mood disorders. (PubMed id 19475602)1, 4 Dempster E.L....Barr C.L. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010)
    513. Genetic variations in vascular endothelial growth factor but not in angiotensin I-converting enzyme genes are associated with endometriosis in Estonian women. (PubMed id 20685027)1, 4 Lamp M....Salumets A. (Eur. J. Obstet. Gynecol. Reprod. Biol. 2010)
    514. Genetic association of angiogenesis- and hypoxia-related gene polymorphisms with osteonecrosis of the femoral head. (PubMed id 20215856)1, 4 Hong J.M....Kim S.Y. (amp 2010)
    515. Gene polymorphisms and related risk factors in Mongolian hypertensive stroke patients. (PubMed id 20831027)1, 4 Huriletemuer H....Hurile H. (Neurosciences (Riyadh) 2010)
    516. Association of angiotensin converting enzyme and angiotensin type 2 receptor gene polymorphisms with renal damage in posterior urethral valves. (PubMed id 20149750)1, 4 Laksmi N.K....Bikash M. (J Pediatr Urol 2010)
    517. The role of plasminogen activator inhibitor-1 and angiotensin-converting enzyme gene polymorphisms in bronchopulmonary dysplasia. (PubMed id 20818980)1, 4 Ince D.A....Ozbek N. (Genet Test Mol Biomarkers 2010)
    518. Association of angiotensin I converting enzyme (insertion/deletion) and angiotensin II type 1 receptor (A1166C) polymorphisms with breast cancer prognostic factors in Iranian population. (PubMed id 20945417)1, 4 Namazi S....Azarpira N. (Mol. Carcinog. 2010)
    519. BELFAST centenarians: a case of optimised cardiovascular risk? (PubMed id 20388089)1, 4 Bennati E....Rea I.M. (Curr. Pharm. Des. 2010)
    520. The association of innate immune response gene polymorphisms and puerperal group A streptococcal sepsis. (PubMed id 20207250)1, 4 Davis S.M....Silver R.M. (Am. J. Obstet. Gynecol. 2010)
    521. Polymorphisms of renin-angiotensin system and natriuretic peptide receptor A genes in patients of Greek origin with a history of myocardial infarction. (PubMed id 20529973)1, 4 Karayannis G....Triposkiadis F. (Angiology 2010)
    522. eNOS and ACE genes influence peripheral arterial disease predisposition in smokers. (PubMed id 20478683)1, 4 Sticchi E....Fatini C. (J. Vasc. Surg. 2010)
    523. The effect of the APOE-epsilon4 allele and ACE-I/D polymorphism on cognition during a two-year follow-up in first-ever stroke patients. (PubMed id 20606435)1, 4 Bour A.M....Verhey F.R. (Dement Geriatr Cogn Disord 2010)
    524. ACE and ACTN3 genes and muscle phenotypes in nonagenarians. (PubMed id 20148371)1, 4 Bustamante-Ara N....Lucia A. (Int J Sports Med 2010)
    525. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2010)
    526. Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project. (PubMed id 20565774)1, 4 Cross D.S....McCarty C.A. (BMC Genet. 2010)
    527. Association of polymorphisms of zinc metalloproteinases with clinical response to stem cell therapy. (PubMed id 20625691)1, 4 Panovsky R....Navratil M. (Herz 2010)
    528. Confirmation that the renin gene distal enhancer polymorphism REN-5312C/T is associated with increased blood pressure. (PubMed id 20160196)1, 4 Vangjeli C....Stanton A.V. (Circ Cardiovasc Genet 2010)
    529. Role of polymorphic variants as genetic modulators of infection in neonatal sepsis. (PubMed id 20463618)1, 4 Abu-Maziad A....Murray J.C. (Pediatr. Res. 2010)
    530. World-class performance in lightweight rowing: is it genetically influenced? A comparison with cyclists, runners and non-athletes. (PubMed id 18801770)1, 4 Muniesa C.A....Lucia A. (Br J Sports Med 2010)
    531. Cardiovascular risk associated with interactions among polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems. (PubMed id 20856803)1, 4 Bentley J.P....van Gilst W.H. (PLoS ONE 2010)
    532. Impact of genetic polymorphisms on platelet function and aspirin resistance. (PubMed id 19923980)1, 4 Pamukcu B....Nisanci Y. (amp 2010)
    533. Can we identify a power-oriented polygenic profile? (PubMed id 20044471)1, 4 Ruiz J.R....Lucia A. (J. Appl. Physiol. 2010)
    534. Angiotensin-converting enzyme gene polymorphism is associated with type 2 diabetes: a meta-analysis. (PubMed id 19655271)1, 4 Zhou J.B....An Y.H. (Mol. Biol. Rep. 2010)
    535. Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. (PubMed id 20534741)1, 4 Corneveaux J.J....Huentelman M.J. (Hum. Mol. Genet. 2010)
    536. The relationship between ACE gene insertion/deletion polymorphism and diabetic retinopathy in Iranian patients with type 2 diabetes. (PubMed id 20565247)1, 4 Nikzamir A....Khalilzadeh O. (Ophthalmic Genet. 2010)
    537. ACTN3 and ACE genotypes in elite Jamaican and US sprinters. (PubMed id 20010124)1, 4 Scott R.A....Pitsiladis Y.P. (Med Sci Sports Exerc 2010)
    538. Genotypic interactions of renin-angiotensin system genes with diabetes type 2 in a Tunisian population. (PubMed id 20580725)1, 4 Mehri S....Hammami M. (Life Sci. 2010)
    539. Soluble fibre (Plantago ovata husk) reduces plasma low-density lipoprotein (LDL) cholesterol, triglycerides, insulin, oxidised LDL and systolic blood pressure in hypercholesterolaemic patients: A randomised trial. (PubMed id 20413122)1, 4 SolA R....Anguera A. (Atherosclerosis 2010)
    540. Gene polymorphisms in angiotensin I converting enzyme (ACE I/D) and angiotensin II converting enzyme (ACE2 C--&gt;T) protect against cerebral malaria in Indian adults. (PubMed id 20117248)1, 4 Dhangadamajhi G....Ranjit M. (Infect. Genet. Evol. 2010)
    541. Evidence for an association between haptoglobin and MnSOD (Val9Ala) gene polymorphisms in essential hypertension based on a Brazilian case-control study. (PubMed id 21053180)1, 4 Miranda-Vilela A.L....Klautau-GuimarALes M.N. (Genet. Mol. Res. 2010)
    542. Association between genetic polymorphisms in the renin-angiotensin system and systolic heart failure revised by a propensity score-based analysis. (PubMed id 20861628)1, 4 Chang S.N....Chiang F.T. (Cardiology 2010)
    543. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (Am. J. Hypertens. 2010)
    544. Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. (PubMed id 20452482)1, 4 Romero R....Menon R. (Am. J. Obstet. Gynecol. 2010)
    545. APOE and ACE polymorphisms and dementia risk in the older population over prolonged follow-up: 10 years of incidence in the MRC CFA Study. (PubMed id 19939808)1, 4 Keage H.A....Brayne C. (Age Ageing 2010)
    546. The ACE Insertion Deletion polymorphism relates to dementia by metabolic phenotype, APOEepsilon4, and age of dementia onset. (PubMed id 18838196)1, 4 Gustafson D.R....Skoog I. (Neurobiol. Aging 2010)
    547. Prevalence of the fibrinogen beta-chain, angiotensin-converting enzyme and plasminogen activator inhibitor-1 polymorphisms in Costa Rican young adults with thrombotic disease. (PubMed id 20535834)1, 4 Hidalgo A....Parajeles A. (Cell Biochem. Funct. 2010)
    548. [Analysis of morpho-functional parameters of the heart and polymorphisms of Renin-Angiotensin-aldosterone system genes in patients with different variants of the course of hypertrophic cardiomyopathy]. (PubMed id 20659024)1, 4 Belenkov Y.N....Fomin A.A. (Kardiologiia 2010)
    549. A propensity score-based case-control study of renin-angiotensin system gene polymorphisms and diastolic heart failure. (PubMed id 19185300)1, 4 Wu C.K....Chiang F.T. (Atherosclerosis 2009)
    550. Angiotensin-converting enzyme genotype and encephalopathy in Chernobyl cleanup workers. (PubMed id 19018872)1, 4 Kehoe A.D....Montgomery H.E. (Eur. J. Neurol. 2009)
    551. Angiotensin-converting enzyme gene DD genotype neither increases susceptibility to acute pancreatitis nor influences disease severity. (PubMed id 19590623)1, 4 Oruc N....Whitcomb D.C. (HPB (Oxford) 2009)
    552. Renin-angiotensin system polymorphisms: a risk factor for progression to end-stage renal disease in vesicoureteral reflux patients. (PubMed id 19288324)1, 4 Akman B....Ozdemir F.N. (Ren Fail 2009)
    553. ACE gene insertion/deletion polymorphism and renal scarring in children with urinary tract infections. (PubMed id 19603195)1, 4 Sekerli E....Gatzola M. (Pediatr. Nephrol. 2009)
    554. Promoter polymorphisms in ACE (angiotensin I-converting enzyme) associated with clinical outcomes in hypertension. (PubMed id 18946466)1, 4 Johnson A.D....Sadee W. (Clin. Pharmacol. Ther. 2009)
    555. Prevalence of thrombophilic mutations and ACE I/D polymorphism in Turkish ischemic stroke patients. (PubMed id 18387982)1, 4 Celiker G....Atac F.B. (Clin. Appl. Thromb. Hemost. 2009)
    556. [Structure of risk factors, damages of target organs, and metabolic changes in patients with arterial hypertension of various age groups]. (PubMed id 19463113)1, 4 BoA-tsov S.A....Pozdniakov I.u.M. (Kardiologiia 2009)
    557. Association of angiotensin-converting enzyme insertion/deletion polymorphism with obesity, cardiovascular risk factors and exercise-mediated changes in Korean women. (PubMed id 19125277)1, 4 Kim K. (Eur. J. Appl. Physiol. 2009)
    558. The angiotensin converting enzyme gene I/D polymorphism in Polish rowers. (PubMed id 19455482)1, 4 Cieszczyk P....Sawczuk M. (Int J Sports Med 2009)
    559. The angiotensin-converting enzyme insertion/deletion polymorphism is associated with phagocytic NADPH oxidase-dependent superoxide generation: potential implication in hypertension. (PubMed id 18647135)1, 4 San JosAc G....Zalba G. (Clin. Sci. 2009)
    560. Methylenetetrahydrofolate reductase and angiotensin-converting enzyme gene polymorphisms among Saudi population from Qassim region. (PubMed id 19810824)1, 4 Algasham A....Settin A.A. (Genet Test Mol Biomarkers 2009)
    561. Gene-gene interaction affects coronary artery disease risk. (PubMed id 19634497)1, 4 MendonAsa M.I....Cardoso A.A. (Rev Port Cardiol 2009)
    562. Genetic variation in CYP27B1 is associated with congestive heart failure in patients with hypertension. (PubMed id 19891555)1, 4 Wilke R.A....McCarty C.A. (Pharmacogenomics 2009)
    563. Are polymorphisms in the ACE and PAI-1 genes associated with recurrent spontaneous miscarriages? (PubMed id 19821806)1, 4 Goodman C....Coulam C. (Am. J. Reprod. Immunol. 2009)
    564. Renin-angiotensin system polymorphisms and the association between use of angiotensin II receptor blockers or angiotensin-converting enzyme inhibitors and the risk of diabetes. (PubMed id 19502258)1, 4 Bozkurt O....Klungel O.H. (J Renin Angiotensin Aldosterone Syst 2009)
    565. Association between renin-angiotensin system gene polymorphism and essential hypertension: a community-based study. (PubMed id 18830250)1, 4 Jiang X....Zhan Y. (J Hum Hypertens 2009)
    566. ACE I/D genotype, adiposity, and blood pressure in children. (PubMed id 19291311)1, 4 Eisenmann J.C....Heelan K.A. (Cardiovasc Diabetol 2009)
    567. Analyses of associations with asthma in four asthma population samples from Canada and Australia. (PubMed id 19247692)1, 4 Daley D....Hudson T.J. (Hum. Genet. 2009)
    568. Human angiotensin-converting enzyme I/D and alpha-actinin 3 R577X genotypes and muscle functional and contractile properties. (PubMed id 18676575)1, 4 McCauley T....Folland J.P. (Exp. Physiol. 2009)
    569. Genetic risk factors in typical haemolytic uraemic syndrome. (PubMed id 19110485)1, 4 Taranta A....Emma F. (Nephrol. Dial. Transplant. 2009)
    570. Lack of genetic association between the angiotensin-converting enzyme gene insertion/deletion polymorphism and longevity in a Han Chinese population. (PubMed id 19502260)1, 4 Yang J.K....Zhang Y.P. (J Renin Angiotensin Aldosterone Syst 2009)
    571. ACE and TGFBR1 genes interact in influencing the susceptibility to abdominal aortic aneurysm. (PubMed id 18550062)1, 4 Lucarini L....Fatini C. (Atherosclerosis 2009)
    572. Angiotensin-converting enzyme insertion/deletion polymorphism in patients with acute and chronic pancreatitis. (PubMed id 19307975)1, 4 Hucl T....PfA1tzer R.H. (amp 2009)
    573. Association between the angiotensin-converting enzyme (insertion/deletion) and angiotensin II type 1 receptor (A1166C) polymorphisms and breast cancer among Brazilian women. (PubMed id 19286759)1, 4 Alves CorrA-a S.A....Guerreiro da Silva I.D. (J Renin Angiotensin Aldosterone Syst 2009)
    574. Association between ACE D allele and elite short distance swimming. (PubMed id 19458960)1, 4 Costa A.M....Breitenfeld L. (Eur. J. Appl. Physiol. 2009)
    575. A study on the association between angiotensin-I converting enzyme I/D dimorphism and type-2 diabetes mellitus. (PubMed id 19861867)1, 4 Chmaisse H.N....Fakhoury R. (Saudi J Kidney Dis Transpl 2009)
    576. Angiotensin-converting enzyme I/D polymorphism in chronic obstructive pulmonary disease. (PubMed id 20156752)1, 4 Pabst S....GrohAc C. (Eur. J. Med. Res. 2009)
    577. The DD genotype of the angiotensin converting enzyme gene independently associates with CMR-derived abnormal microvascular perfusion in patients with a first anterior ST-segment elevation myocardial infarction treated with thrombolytic agents. (PubMed id 19664801)1, 4 Bodi V....Llacer A. (Thromb. Res. 2009)
    578. The effect of angiotensin-converting enzyme genotype on acute mountain sickness and summit success in trekkers attempting the summit of Mt. Kilimanjaro (5,895 m). (PubMed id 19030872)1, 4 Kalson N.S....Montgomery H. (Eur. J. Appl. Physiol. 2009)
    579. ACE polymorphism and response to electroconvulsive therapy in major depression. (PubMed id 19409959)1, 4 Stewart J.A....Leinonen E. (Neurosci. Lett. 2009)
    580. Angiotensin-converting enzyme gene and retinal arteriolar narrowing: the Funagata Study. (PubMed id 19369957)1, 4 Tanabe Y....Yamashita H. (J Hum Hypertens 2009)
    581. Physiogenomic comparison of edema and BMI in patients receiving rosiglitazone or pioglitazone. (PubMed id 18996102)1, 4 RuaA+o G....Hanks S. ( international journal of clinical chemistry 2009)
    582. Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is associated with schizophrenia in a Spanish population. (PubMed id 18986708)1, 4 Crescenti A....Lafuente A. (Psychiatry Res 2009)
    583. Angiotensin-converting enzyme and adducin-1 polymorphisms in women with preeclampsia and gestational hypertension. (PubMed id 19443911)1, 4 MandA^ C....Cetin I. (Reprod Sci 2009)
    584. Angiotensin-converting enzyme gene insertion/deletion polymorphism in Egyptian patients with myocardial infarction. (PubMed id 19502257)1, 4 Settin A....Noaman A. (J Renin Angiotensin Aldosterone Syst 2009)
    585. ACE I/D and G2350A polymorphisms in Pakistani hypertensive population of Punjab. (PubMed id 19811356)1, 4 Alvi F.M. and Hasnain S. (Clin. Exp. Hypertens. 2009)
    586. Prevalence of the angiotensin I converting enzyme gene insertion/deletion polymorphism in a healthy Turkish population. (PubMed id 19390959)1, 4 Berdeli A. and Cam F.S. (Biochem. Genet. 2009)
    587. Lack of association between angiotensin I-converting enzyme insertion/deletion polymorphism and psoriasis or psoriatic arthritis in Spain. (PubMed id 19930490)1, 4 Coto-Segura P....Santos-Juanes J. (Int. J. Dermatol. 2009)
    588. Nutrigenetics: links between genetic background and response to Mediterranean-type diets. (PubMed id 19689828)1, 4 Lairon D....Planells R. (Public Health Nutr 2009)
    589. Gene polymorphisms of renin angiotensin system and serotonin transporter gene in patients with vasovagal syncope. (PubMed id 19408837)1, 4 Mudrakova K....Tkac I. (Bratisl Lek Listy 2009)
    590. Different Mechanisms for the Progression of CKD with ACE Gene Polymorphisms. (PubMed id 19293592)1, 4 Nakayama Y....Tomita K. (Nephron Clin Pract 2009)
    591. Effect of ID ACE gene polymorphism on dietary composition and obesity-related anthropometric parameters in the Czech adult population. (PubMed id 19609587)1, 4 Bienertova-Vasku J....Vasku A. (amp 2009)
    592. Actigenetic of ACE gene polymorphism in Czech obese sedentary females. (PubMed id 19857036)1, 4 SuchA!nek P....AdA!mkovA! V. (Physiol Res 2009)
    593. A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. (PubMed id 19131662)1, 4 Wang X....Cook N.R. ( a journal of cerebral circulation 2009)
    594. Genetic variant of the Renin-Angiotensin system and diabetes influences blood pressure response to Angiotensin receptor blockers. (PubMed id 19509012)1, 4 Konoshita T....Pinet F. (Diabetes Care 2009)
    595. High frequency of the D allele of the angiotensin-converting enzyme gene in Arabic populations. (PubMed id 19505317)1, 4 Salem A.H. and Batzer M.A. (BMC Res Notes 2009)
    596. Is there an optimum endurance polygenic profile? (PubMed id 19237423)1, 4 Ruiz J.R....Lucia A. (J. Physiol. (Lond.) 2009)
    597. The contribution of six polymorphisms to cardiovascular risk in a Dutch high-risk primary care population: the HIPPOCRATES project. (PubMed id 19242491)1, 4 Plat A.W....Kroon A.A. (J Hum Hypertens 2009)
    598. Gene polymorphisms of ACE and the angiotensin receptor AT2R1 influence serum ACE levels in sarcoidosis. (PubMed id 20560294)1, 4 Biller H....Zissel G. (Sarcoidosis Vasc Diffuse Lung Dis 2009)
    599. Association of von Willebrand factor activity with ACE I/D and MTHFR C677T polymorphisms in migraine. (PubMed id 19298544)1, 4 Tietjen G.E....Joe B. (Cephalalgia 2009)
    600. Angiotensin-converting enzyme gene polymorphism in hypertensive rural population of Haryana, India. (PubMed id 20009302)1, 4 Gupta S....Sehajpal P.K. (J Emerg Trauma Shock 2009)
    601. ACE insertion/deletion polymorphism and its relationships to the components of metabolic syndrome in elderly Slovaks. (PubMed id 19462670)1, 4 SivA!kovA! D....BlazA-cek P. ( Bericht über die biologisch-anthropologische Literatur 2009)
    602. Interaction between genetic polymorphisms and stressful life events in first episode depression. (PubMed id 19339052)1, 4 Bukh J.D....Vedel Kessing L. (J Affect Disord 2009)
    603. Lack of association of angiotensin-converting enzyme insertion/deletion polymorphism and myocardial infarction at very young ages. (PubMed id 19552566)1, 4 Rallidis L.S....Kremastinos D.T. (Biomarkers 2009)
    604. Renin-angiotensin gene polymorphisms in relation to severe chronic periodontitis. (PubMed id 19236533)1, 4 GA1rkan A....Berdeli A. (J. Clin. Periodontol. 2009)
    605. The genetics of abdominal aortic aneurysms: a comprehensive meta-analysis involving eight candidate genes in over 16,700 patients. (PubMed id 20302034)1, 4 McColgan P....Sharma P. (Int Surg 2009)
    606. Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta. (PubMed id 18813964)1, 4 Kauwe J.S....Goate A.M. (Neurogenetics 2009)
    607. Association of ACE I/D gene polymorphism with vascular dementia: a meta-analysis. (PubMed id 19073835)1, 4 Liu H....Wang Y. (J Geriatr Psychiatry Neurol 2009)
    608. Association between IL4 (-590), ACE (I)/(D), CCR5 (Delta32), CTLA4 (+49) and IL1-RN (VNTR in intron 2) gene polymorphisms and vitiligo. (PubMed id 19129082)1, 4 Pehlivan S....Ozkinay C. (Eur J Dermatol 2009)
    609. Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients. (PubMed id 18484085)1, 4 Heck A....Ising M. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009)
    610. Association of apolipoprotein E and angiotensin converting enzyme gene polymorphisms with the multidimensional impairment in older patients. (PubMed id 19653879)1, 4 Pilotto A....Dallapiccola B. (Rejuvenation Res 2009)
    611. Insertion/deletion polymorphism of angiotensin converting enzyme gene in Korean hypertensive adolescents. (PubMed id 19466520)1, 4 Park E.Y....Hong Y.M. (Heart Vessels 2009)
    612. Genetic variation in the renin-angiotensin system and arterial stiffness. The Rotterdam Study. (PubMed id 19811349)1, 4 Sie M.P....Witteman J.C. (Clin. Exp. Hypertens. 2009)
    613. Gene polymorphisms related to angiogenesis, inflammation and thrombosis that influence risk for oral cancer. (PubMed id 18674955)1, 4 Vairaktaris E....Patsouris E. (Oral Oncol. 2009)
    614. Association of ACE (I/D) polymorphism with metabolic syndrome and hypertension in two ethnic groups in Slovakia. (PubMed id 20405703)1, 4 DankovA! Z....BlazA-cek P. ( Bericht über die biologisch-anthropologische Literatur 2009)
    615. The association between arterial stiffness and the angiotensin II type 1 receptor (A1166C) polymorphism is influenced by the use of cardiovascular medication. (PubMed id 19145770)1, 4 Plat A.W....Kroon A.A. (J. Hypertens. 2009)
    616. Angiotensin-converting enzyme insertion/deletion and angiotensin type 1 receptor A1166C polymorphisms as genetic risk factors in benign prostatic hyperplasia and prostate cancer. (PubMed id 20026870)1, 4 Sierra DA-az E....MorA!n Moguel M.C. (J Renin Angiotensin Aldosterone Syst 2009)
    617. Association of angiotensin-converting enzyme intron 16 insertion/deletion polymorphism with history of foetal loss. (PubMed id 19717502)1, 4 Bukreeva L....Hoppe B. (J Renin Angiotensin Aldosterone Syst 2009)
    618. Synergistic effects of ACE (I/D) and ApoE (HhaI) gene polymorphisms among the adult Asian Indians with and without metabolic syndrome. (PubMed id 19800705)1, 4 Das M....Ghosh A. (Diabetes Res. Clin. Pract. 2009)
    619. Association of angiotensin-converting enzyme gene 2350G&gt;A polymorphism with myocardial infarction in a Chinese population. (PubMed id 18445609)1, 4 Min Pan ....Zhu J.H. (Clin. Appl. Thromb. Hemost. 2009)
    620. A candidate gene approach to genetic prognostic factors of IgA nephropathy--a result of Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgA Nephropathy (PREDICT-IgAN). (PubMed id 19420105)1, 4 Yamamoto R....Rakugi H. (Nephrol. Dial. Transplant. 2009)
    621. Is there an ACE ID - ACTN3 R577X polymorphisms interaction that influences sprint performance? (PubMed id 20013558)1, 4 Eynon N....Meckel Y. (Int J Sports Med 2009)
    622. Relation between angiotensin-converting enzyme I/D gene polymorphism and pulse pressure in patients with a first anterior acute myocardial infarction. (PubMed id 19196567)1, 4 OztA1rk O. and OztA1rk U. (Anadolu Kardiyol Derg 2009)
    623. Association between ACE gene I/D polymorphisms and hyperandrogenism in women with polycystic ovary syndrome (PCOS) and controls. (PubMed id 19602270)1, 4 Sun J....Wang Y. (BMC Med. Genet. 2009)
    624. An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3. (PubMed id 19105203)1, 4 Edwards T.L....Ritchie M.D. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009)
    625. Lack of association between ACE and bradykinin B2 receptor gene polymorphisms and ACE inhibitor-induced coughing in hypertensive Koreans. (PubMed id 19744011)1, 4 Woo S.W....Lee S.H. (J Clin Pharm Ther 2009)
    626. Perioperative genomic profiles using structure-specific oligonucleotide probes. (PubMed id 19474452)1, 4 Hogan K.J....Domanico M.J. (amp 2009)
    627. Genetic modifiers of liver disease in cystic fibrosis. (PubMed id 19738092)1, 4 Bartlett J.R....Knowles M.R. (JAMA 2009)
    628. Angiotensin-converting enzyme gene insertion/deletion polymorphism frequency in normotensive children with a positive family history of essential hypertension. (PubMed id 19863706)1, 4 Camci L....Ucar B. (J Paediatr Child Health 2009)
    629. Lack of association between TGF-beta-1 genotypes and microalbuminuria in essential hypertensive men. (PubMed id 19176688)1, 4 Dell'Omo G....Pedrinelli R. (Nephrol. Dial. Transplant. 2009)
    630. A role for succinate dehydrogenase genes in low chemoresponsiveness to hypoxia? (PubMed id 19768395)1, 4 Richalet J.P....Elghozi J.L. (Clin. Auton. Res. 2009)
    631. Angiotensin-converting enzyme polymorphism and completed suicide: an association in Caucasians and evidence for a link with a method of self-injury. (PubMed id 19439995)1, 4 Fudalej S....PA8oski R. (Neuropsychobiology 2009)
    632. Multi-locus interactions of vascular homeostasis genes in essential hypertension: a gender-based study. (PubMed id 19379721)1, 4 Kumar R....Qadar Pasha M.A. ( international journal of clinical chemistry 2009)
    633. The influence of six cardiovascular polymorphisms on a first event of ischemic heart disease is modified by sex and age. (PubMed id 19779330)1, 4 Plat A.W....Kroon A.A. (Coron. Artery Dis. 2009)
    634. Sex-specific effect of the alpha-adducin (G460W) and AGTR1 (A1166C) polymorphism on carotid intima-media thickness. (PubMed id 19620885)1, 4 Plat A.W....Kroon A.A. (J. Hypertens. 2009)
    635. Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. (PubMed id 19156168)1, 4 Need A.C....Goldstein D.B. (Eur. J. Hum. Genet. 2009)
    636. Endurance performance: genes or gene combinations? (PubMed id 18651373)1, 4 GA^mez-Gallego F....Lucia A. (Int J Sports Med 2009)
    637. Methylene tetrahydrofolate reductase and angiotensin converting enzyme gene polymorphisms related to overweight/obesity among Saudi subjects from Qassim Region. (PubMed id 19893205)1, 4 Settin A.A....Ismail H. (Dis. Markers 2009)
    638. Polymorphism in the angiotensin II type 1 receptor (AGTR1) is associated with age at diagnosis in pulmonary arterial hypertension. (PubMed id 19332265)1, 4 Chung W.K....Morse J.H. (J. Heart Lung Transplant. 2009)
    639. Phenotype-genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling. (PubMed id 19479237)1, 4 Song X.Y....Chan J.C. (Diabetologia 2009)
    640. A candidate gene association study of 77 polymorphisms in migraine. (PubMed id 19559392)1, 4 SchA1rks M....Zee R.Y. (J Pain 2009)
    641. Relationship between preterm labor and thrombophilic gene polymorphism: A prospective sequential cohort study. (PubMed id 19776610)1, 4 Uvuz F....Bilge U. (Gynecol. Obstet. Invest. 2009)
    642. Angiotensin-converting enzyme (ACE, I/D) gene polymorphism and susceptibility to abdominal aortic aneurysm or aortoiliac occlusive disease. (PubMed id 18718603)1, 4 Korcz A....SA8omski R. (J. Surg. Res. 2009)
    643. Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach. (PubMed id 19263529)1, 4 Zee R.Y....Glynn R.J. ( international journal of clinical chemistry 2009)
    644. MTHFR and ACE gene polymorphisms and risk of vascular and degenerative dementias in the elderly. (PubMed id 19716217)1, 4 Pandey P....Mittal B. (Brain Cogn 2009)
    645. Reciprocal interactions of obstructive sleep apnea and hypertension associated with ACE I/D polymorphism in males. (PubMed id 19482546)1, 4 Koyama R.G....Pedrazzoli M. (Sleep Med. 2009)
    646. Candidate gene polymorphisms for ischemic stroke. (PubMed id 19729601)1, 4 Matarin M....Meschia J.F. ( a journal of cerebral circulation 2009)
    647. Genotype distributions in top-level soccer players: a role for ACE? (PubMed id 19277943)1, 4 Juffer P....Lucia A. (Int J Sports Med 2009)
    648. An age effect on the association of common variants of ACE with Alzheimer's disease. (PubMed id 19539712)1, 4 Helbecque N....Amouyel P. (Neurosci. Lett. 2009)
    649. Angiotensin-converting enzyme insertion/deletion gene polymorphism and progression of Chagas' cardiomyopathy. (PubMed id 19268079)1, 4 Pascuzzo-Lima C....Bonfante-Cabarcas R.A. (Rev Esp Cardiol 2009)
    650. Impact of genetic polymorphisms of the renin-angiotensin system and of non-genetic factors on kidney transplant function--a single-center experience. (PubMed id 19681973)1, 4 Siekierka-Harreis M....Blume C. (Clin Transplant 2009)
    651. A pilot study of genetic polymorphisms and hemodialysis vascular access thrombosis. (PubMed id 19210273)1, 4 Brophy D.F....Gehr T.W. (Hemodial Int 2009)
    652. Association of genetic variants with chronic kidney disease in individuals with different lipid profiles. (PubMed id 19578796)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2009)
    653. Influence of angiotensinogen and angiotensin-converting enzyme polymorphisms on cardiac hypertrophy and improvement on maximal aerobic capacity caused by exercise training. (PubMed id 19404196)1, 4 Alves G.B....NegrALo C.E. (amp 2009)
    654. Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants. (PubMed id 19527514)1, 4 Menon R....Thorsen P. (amp 2009)
    655. Association between renin-angiotensin system gene polymorphism and recurrent wheezing in Chinese children: a 4-year follow-up study. (PubMed id 19383228)1, 4 Guo S....Sheng J.Y. (J. Int. Med. Res. 2009)
    656. [Sudden cardiac death and polymorphism of genes-candidates of cardiovascular diseases]. (PubMed id 19463119)1, 4 Voevoda M.I....Romashenko A.G. (Kardiologiia 2009)
    657. Angiotensin-converting enzyme insertion/deletion polymorphism has no effect on the risk of atherosclerotic stroke or hypertension. (PubMed id 19596363)1, 4 Tascilar N....Baris S. (J. Neurol. Sci. 2009)
    658. Clinical and genetic risk factors for suicide under the influence of alcohol in a Polish sample. (PubMed id 19734157)1, 4 Fudalej S....Blow F.C. (Alcohol Alcohol. 2009)
    659. Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. (PubMed id 19019335)1, 4 Velez D.R....Menon R. (Am. J. Obstet. Gynecol. 2009)
    660. Association of the insertion/deletion polymorphism of the angiotensin-converting enzyme gene with type 2 diabetes in two ethnic groups of Jerba Island in Tunisia. (PubMed id 19286757)1, 4 Baroudi T....Benammar-Elgaaied A. (J Renin Angiotensin Aldosterone Syst 2009)
    661. Angiotensin converting enzyme gene polymorphism in Turkish asthmatic patients. (PubMed id 19484664)1, 4 EryA1ksel E....CirakoA9lu B. (J Asthma 2009)
    662. Angiotensinogen, angiotensine converting enzyme and plasminogen activator inhibitor-1 gene polymorphism in chronic allograft dysfunction. (PubMed id 18454324)1, 4 Azarpira N....Geramizadeh B. (Mol. Biol. Rep. 2009)
    663. Variation in Renin-Angiotensin system and salt-sensitivity genes and the risk of diabetes mellitus associated with the use of thiazide diuretics. (PubMed id 19247266)1, 4 Bozkurt O....Klungel O.H. (Am. J. Hypertens. 2009)
    664. Genetic polymorphism of Angiotensin-Converting Enzyme is not associated with the development of Parkinson's disease and of L-dopa-induced adverse effects. (PubMed id 18805557)1, 4 Pascale E....Meco G. (J. Neurol. Sci. 2009)
    665. Assessment of Alzheimer's disease case-control associations using family-based methods. (PubMed id 18830724)1, 4 Schjeide B.M....Bertram L. (Neurogenetics 2009)
    666. Genetic factors are relevant and independent determinants of antihypertensive drug effects in a multiracial population. (PubMed id 19779464)1, 4 van Rijn-Bikker P.C....Koopmans R.P. (Am. J. Hypertens. 2009)
    667. [Genetic determinants of cardiovascular remodeling in Uzbek patients with essential hypertension]. (PubMed id 19253715)1, 4 Eliseeva M.R....Abdullaeva G.Z.h. (Ter. Arkh. 2009)
    668. Arteriovenous fistula patency associated with angiotensin-converting enzyme I/D polymorphism and ACE inhibition or AT1 receptor blockade. (PubMed id 19142023)1, 4 Moon J.Y....Chung J.H. (Nephron Clin Pract 2009)
    669. The relationship between ACE gene ID polymorphism and aerobic capacity in Asian rugby players. (PubMed id 19907891)1, 4 Goh K.P....Sum C.F. (Singapore Med J 2009)
    670. A common variant in DRD3 gene is associated with risperidone-induced extrapyramidal symptoms. (PubMed id 19506579)1, 4 GassA^ P....Lafuente A. (Pharmacogenomics J. 2009)
    671. Analysis of polymorphism in renin angiotensin system and other related genes in South Indian chronic kidney disease patients. (PubMed id 19520069)1, 4 Anbazhagan K....Selvam G.S. ( international journal of clinical chemistry 2009)
    672. Angiotensin-converting enzyme and angiotensin II receptor subtype 2 genotypes in type 1 diabetes and severe hypoglycaemia requiring emergency treatment: a case cohort study. (PubMed id 19820429)1, 4 Pedersen-Bjergaard U....Thorsteinsson B. (Pharmacogenet. Genomics 2009)
    673. ACE (I/D) polymorphism and response to treatment in coronary artery disease: a comprehensive database and meta-analysis involving study quality evaluation. (PubMed id 19497121)1, 4 Kitsios G. and Zintzaras E. (BMC Med. Genet. 2009)
    674. Impact of renin-angiotensin system polymorphisms on renal haemodynamic responsiveness to acute angiotensin-converting enzyme inhibition in type 2 diabetes mellitus. (PubMed id 19286758)1, 4 Volkan-Salanci B....Erbas B. (J Renin Angiotensin Aldosterone Syst 2009)
    675. The relationship between slow coronary flow and angiotensin converting enzyme and ATIIR1 gene polymorphisms. (PubMed id 19245071)1, 4 Yalcin A.A....Oguzhan A. (J Natl Med Assoc 2009)
    676. Analysis of candidate genes and hypertension in African American adults. (PubMed id 19341158)1, 4 Whitfield K.E....Vandenbergh D.J. (amp 2009)
    677. Lack of association between ACE ID polymorphism and colorectal cancer in Romanian patients. (PubMed id 19943553)1, 4 Toma M....GavrilA8 L. (Chirurgia (Bucur) 2009)
    678. Histologic characterization of hypertrophic cardiomyopathy with and without myofilament mutations. (PubMed id 19853701)1, 4 McLeod C.J....Ackerman M.J. (Am. Heart J. 2009)
    679. Meta-analysis of the ACE gene polymorphism in cerebral infarction. (PubMed id 19294883)1, 4 Tao H.M....Chen G.Z. (Can J Neurol Sci 2009)
    680. The environmental and genetic evidence for the association of hyperlipidemia and hypertension. (PubMed id 19155782)1, 4 Ruixing Y....Shangling P. (J. Hypertens. 2009)
    681. Integrative predictive model of coronary artery calcification in atherosclerosis. (PubMed id 19948975)1, 4 McGeachie M....Ramoni M.F. (Circulation 2009)
    682. An alternative method for genotyping of the ACE I/D polymorphism. (PubMed id 18622756)1, 4 Glenn K.L....Rothschild M.F. (Mol. Biol. Rep. 2009)
    683. Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome. (PubMed id 19056482)1, 4 Yoshida T....Yamada Y. (Genomics 2009)
    684. An angiotensin-1 converting enzyme polymorphism is associated with allostatic load mediated by C-reactive protein, interleukin-6 and cortisol. (PubMed id 19081678)1, 4 Smith A.K....Rajeevan M.S. (Psychoneuroendocrinology 2009)
    685. Survival in type 2 diabetic patients in dialysis and the number of risk alleles in polymorphisms of the renin-angiotensin system genes. (PubMed id 19014923)1, 4 PadrA^-Miquel A....Navarro-Moreno M.A. (Clin. Biochem. 2009)
    686. Meta-analysis of genetic polymorphisms and gastric cancer risk: variability in associations according to race. (PubMed id 19375306)1, 4 Loh M....Soong R. (Eur. J. Cancer 2009)
    687. Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994. (PubMed id 18936436)1, 4 Chang M.H....Khoury M.J. (Am. J. Epidemiol. 2009)
    688. The rationale and design of the PERindopril GENEtic association study (PERGENE): a pharmacogenetic analysis of angiotensin-converting enzyme inhibitor therapy in patients with stable coronary artery disease. (PubMed id 19082699)1, 4 Brugts J.J....Simoons M.L. (Cardiovasc Drugs Ther 2009)
    689. Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies. (PubMed id 19956635)1, 4 Holmes M.V....Casas J.P. (PLoS ONE 2009)
    690. Gender-dependent effect of ACE I/D and AGT M235T polymorphisms on the progression of urinary albumin excretion in Taiwanese with type 2 diabetes. (PubMed id 18849600)1, 4 Tien K.J....Hsieh M.C. (Am. J. Nephrol. 2009)
    691. Angiotensin I-converting enzyme I/D polymorphism and suicidal behaviors. (PubMed id 18521860)1, 4 Sparks D.L....Helbecque N. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009)
    692. Angiotensin-converting enzyme gene and endothelial nitric oxide synthase gene polymorphisms in BehAset's disease with or without ocular involvement. (PubMed id 19255721)1, 4 Dursun A....Akduman L. (Inflamm. Res. 2009)
    693. Is there a gender difference between ACE gene and race distance? (PubMed id 19935855)1, 4 Min S.K....Nakazato K. (Appl Physiol Nutr Metab 2009)
    694. A polymorphism in the angiotensin-converting enzyme gene is associated with smoking behavior. (PubMed id 19203483)1, 4 Baghai T.C....Bondy B. (J Clin Psychiatry 2008)
    695. Hemodynamic parameters and heart rate variability during a tilt test in relation to gene polymorphism of renin-angiotensin and serotonin system. (PubMed id 19067809)1, 4 Mitro P....Valocik G. (Pacing Clin Electrophysiol 2008)
    696. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. (PubMed id 18583979)1, 4 Allen N.C....Bertram L. (Nat. Genet. 2008)
    697. Candidate gene association studies in abdominal aortic aneurysm disease: a review and meta-analysis. (PubMed id 17920311)1, 4 Thompson A.R....Humphries S.E. (Eur J Vasc Endovasc Surg 2008)
    698. Lack of association between angiotensin-converting enzyme gene polymorphism and type I aortic dissection. (PubMed id 18652767)1, 4 Tangurek B....Bolca O. (J. Int. Med. Res. 2008)
    699. Renin-angiotensin system gene polymorphisms and diastolic heart failure. (PubMed id 19021695)1, 4 Wu C.K....Chiang F.T. (Eur. J. Clin. Invest. 2008)
    700. No relation between angiotensin-converting enzyme gene polymorphism and pseudoexfoliation. (PubMed id 18025834)1, 4 Tekeli O....Elhan A.H. (Ophthalmic Res. 2008)
    701. [Association between indoor coal-burning pollutants associated with asthmatic susceptible genetic polymorphisms in childhood asthma]. (PubMed id 18589597)1, 4 Yuan P....et al . (Wei Sheng Yan Jiu 2008)
    702. ACE genotype, body weight changes and target organ damage in renal transplant recipients. (PubMed id 19034872)1, 4 Stratta P....Pirisi M. (J. Nephrol. 2008)
    703. Haplotypes across ACE and the risk of Alzheimer's disease: the three-city study. (PubMed id 18431000)1, 4 Bruandet A....Helbecque N. (J. Alzheimers Dis. 2008)
    704. Renin-angiotensin system gene polymorphisms and atrial fibrillation: a regression approach for the detection of gene-gene interactions in a large hospitalized population. (PubMed id 18239384)1, 4 Tsai C.T....Lin J.L. (Cardiology 2008)
    705. Renin-angiotensin system polymorphisms and risk of hypertension: influence of environmental factors. (PubMed id 18550936)1, 4 Forman J.P....Curhan G.C. (J Clin Hypertens (Greenwich) 2008)
    706. [Polymorphisms of genes of rennin-angiotensine system and their correlation with psychological manifestations of birth stress]. (PubMed id 19062524)1, 4 Spivak I.M....Spivak D.L. (Tsitologiia 2008)
    707. The I allele of the ACE gene is associated with improved exercise capacity in women with McArdle disease. (PubMed id 17616548)1, 4 GA^mez-Gallego F....Lucia A. (Br J Sports Med 2008)
    708. Influence of angiotensin-I-converting-enzyme insertion/deletion gene polymorphism on perioperative hemodynamics after coronary bypass graft surgery. (PubMed id 18431347)1, 4 Popov A.F....Schoendube F.A. (J Cardiovasc Surg (Torino) 2008)
    709. Association between angiotensin-converting enzyme gene polymorphisms and exercise performance in patients with COPD. (PubMed id 18713090)1, 4 Zhang X....Zhang J. (Respirology 2008)
    710. [Genetic predisposition to systemic complications of arterial hypertension in maintenance haemodialysis patients]. (PubMed id 19112833)1, 4 Bzoma B....Rutkowski B. (Pol. Merkur. Lekarski 2008)
    711. Randomized, placebo-controlled, double-blind pilot trial of ramipril in McArdle's disease. (PubMed id 18098237)1, 4 Martinuzzi A....Lodi R. (amp 2008)
    712. Angiotensin-converting enzyme gene polymorphism in arrhythmogenic right ventricular dysplasia: is DD genotype helpful in predicting syncope risk? (PubMed id 19126662)1, 4 Ozben B....Adalet K. (J Renin Angiotensin Aldosterone Syst 2008)
    713. RAS gene polymorphisms, classical risk factors and the advent of coronary artery disease in the Portuguese population. (PubMed id 18637188)1, 4 Freitas A.I....Brehm A. (BMC Cardiovasc Disord 2008)
    714. The D allele of angiotensin-converting enzyme polymorphism as a predictor of renal function decline over 4 years in an apparently healthy Chinese population aged 60 and older. (PubMed id 18284535)1, 4 Lee Y.T....Sheu S.H. (J Am Geriatr Soc 2008)
    715. The renin-angiotensin-aldosterone system in cerebral small vessel disease. (PubMed id 18446309)1, 4 Brenner D....Amarenco P. (J. Neurol. 2008)
    716. Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. (PubMed id 18818748)1, 4 Velez D.R....Menon R. (PLoS ONE 2008)
    717. Genetic polymorphism, medical therapy and sequential cardiac function in patients with heart failure. (PubMed id 18516385)1, 4 Cuoco M.A....Mansur A.J. (Arq. Bras. Cardiol. 2008)
    718. Angiotensin-converting enzyme genotype may predict survival following major trauma. (PubMed id 18955615)1, 4 Kehoe A.D....Montgomery H.E. (Emerg Med J 2008)
    719. [Gene polymorphism of the renin-angiotensin system in six ethnic/geographic regions of Belarus]. (PubMed id 18672804)1, 4 Sivitskaia L.N....Davydenko O.G. (Genetika 2008)
    720. Study on a possible effect of four longevity candidate genes (ACE, PON1, PPAR-gamma, and APOE) on human fertility. (PubMed id 18443916)1, 4 Corbo R.M....Scacchi R. (Biogerontology 2008)
    721. Association of angiotensin-converting enzyme gene dimorphisms with severity of lupus disease. (PubMed id 18711292)1, 4 Rabbani M.A....Frossard P.M. (Saudi J Kidney Dis Transpl 2008)
    722. Angiotensinogen and angiotensin II type 1 receptor gene polymorphisms and changes in repolarization parameters in elderly Chinese: a 4-year follow-up study. (PubMed id 18364271)1, 4 Lee Y.T....Sheu S.H. (Kaohsiung J. Med. Sci. 2008)
    723. Prevalence of prothrombotic polymorphisms in Greece. (PubMed id 19072566)1, 4 Gialeraki A....Travlou A. (Genet. Test. 2008)
    724. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PubMed id 18660489)1, 4 Lu Y....Boer J.M. (J. Lipid Res. 2008)
    725. Angiotensin-converting enzyme insertion/deletion polymorphism is not associated with susceptibility and outcome in sepsis and acute respiratory distress syndrome. (PubMed id 18060663)1, 4 Villar J.... . (Intensive Care Med 2008)
    726. Lp(a) and risk of recurrent cardiac events in obese postinfarction patients. (PubMed id 18927546)1, 4 Corsetti J.P....Sparks C.E. (Obesity (Silver Spring) 2008)
    727. Interaction effects between total energy and macronutrient intakes and angiotensin-converting enzyme 1 ( ACE) I/D polymorphism on adiposity-related phenotypes in toddlers and preschoolers: the Growth, Exercise and Nutrition Epidemiological Study in preSchoolers: the GENESIS study. [corrected]. (PubMed id 18479585)1, 4 Kourlaba G....Manios Y. (Br. J. Nutr. 2008)
    728. Association of angiotensin-converting enzyme (ACE) gene insertion-deletion polymorphism with spondylarthropathies. (PubMed id 17713861)1, 4 Shehab D.K....Haider M.Z. (J. Biomed. Sci. 2008)
    729. Angiotensin-converting enzyme gene polymorphism and the progression rate of focal segmental glomerulosclerosis in Iranian children. (PubMed id 19076285)1, 4 Gheissari A....Naeini A.E. (Nephrology (Carlton) 2008)
    730. Prevalence of angiotensin-converting enzyme gene insertion-deletion polymorphism in patients with primary knee osteoarthritis. (PubMed id 18565253)1, 4 Shehab D.K....Haider M.Z. (Clin. Exp. Rheumatol. 2008)
    731. The angiotensin converting enzyme insertion/deletion polymorphism and differences in fasting plasma glucose in Hindustani Surinamese, African Surinamese and ethnic Dutch: the population-based SUNSET-study. (PubMed id 18439702)1, 4 van Valkengoed I.G....Holleman F. (Diabetes Res. Clin. Pract. 2008)
    732. Angiotensin II type 1 receptor 1166C polymorphism is associated with abdominal aortic aneurysm in three independent cohorts. (PubMed id 18239157)1, 4 Jones G.T....van Rij A.M. (Arterioscler. Thromb. Vasc. Biol. 2008)
    733. Serum angiotensin converting enzyme and the obstructive sleep apnea hypopnea syndrome. (PubMed id 18763423)1, 4 Benjamin J.A....Lewis K.E. (J Clin Sleep Med 2008)
    734. The genetics of primary haemorrhagic stroke, subarachnoid haemorrhage and ruptured intracranial aneurysms in adults. (PubMed id 19008959)1, 4 Peck G....Sharma P. (PLoS ONE 2008)
    735. Angiotensin-converting enzyme D allele does not influence susceptibility to acute hypoxic respiratory failure in children. (PubMed id 18787808)1, 4 Plunkett A....Peters M.J. (Intensive Care Med 2008)
    736. Adiposity gain during childhood, ACE I/D polymorphisms and metabolic outcomes. (PubMed id 18551123)1, 4 Ponsonby A.L....Dwyer T. (Obesity (Silver Spring) 2008)
    737. Gender differences in genetic risk profiles for cardiovascular disease. (PubMed id 18974842)1, 4 Silander K....Peltonen L. (PLoS ONE 2008)
    738. Impact of the preintervention rate of renal function decline on outcome of renoprotective intervention. (PubMed id 18077786)1, 4 Lely A.T....Navis G. (Clin J Am Soc Nephrol 2008)
    739. Meta-analysis of genetic studies from journals published in China of ischemic stroke in the Han Chinese population. (PubMed id 18511872)1, 4 Xu X....Liu L. (Cerebrovasc. Dis. 2008)
    740. Correlation of angiotensin converting enzyme activity and the genotypes of the I/D polymorphism in the ACE gene with preterm birth and birth weight. (PubMed id 18755533)1, 4 Uma R....Murphy D.J. (Eur. J. Obstet. Gynecol. Reprod. Biol. 2008)
    741. Association of angiotensin-converting enzyme insertion-deletion polymorphism with preeclampsia. (PubMed id 18756878)1, 4 MiskoviA8 B....Stipoljev F. (Coll Antropol 2008)
    742. Genetic variants in the renin-angiotensin system genes are associated with cardiovascular-renal-related risk factors in Mexican Americans. (PubMed id 18985387)1, 4 Thameem F....Arar N.H. (Hum. Genet. 2008)
    743. Angiotensin-converting enzyme genotype and late respiratory complications of mustard gas exposure. (PubMed id 18702808)1, 4 Hosseini-Khalili A.R....Ghanei M. (BMC Pulm Med 2008)
    744. Genotype-phenotype associations between chymase and angiotensin-converting enzyme gene polymorphisms in chronic systolic heart failure patients. (PubMed id 18641516)1, 4 Amir R.E....Lewis B.S. (Genet. Med. 2008)
    745. Association of renin-angiotensin and endothelial nitric oxide synthase gene polymorphisms with blood pressure progression and incident hypertension: prospective cohort study. (PubMed id 18698212)1, 4 Conen D....Zee R.Y. (J. Hypertens. 2008)
    746. Association of renin-angiotensin system and natriuretic peptide receptor A gene polymorphisms with hypertension in a Hellenic population. (PubMed id 19126660)1, 4 Tsezou A....Triposkiadis F. (J Renin Angiotensin Aldosterone Syst 2008)
    747. ACE and MTHFR gene polymorphisms in unexplained recurrent pregnancy loss. (PubMed id 18588608)1, 4 Vettriselvi V....Venkatachalam P. (J. Obstet. Gynaecol. Res. 2008)
    748. Association of insertion/deletion polymorphism of the angiotensin-converting enzyme gene with angio-oedema accompanying chronic urticaria but not chronic urticaria without angio-oedema or the autologous serum skin test response. (PubMed id 18181977)1, 4 Akcali C....Aynacioglu A.S. (J Eur Acad Dermatol Venereol 2008)
    749. Angiotensin-converting enzyme genotype and arterial oxygen saturation at high altitude in Peruvian Quechua. (PubMed id 18578648)1, 4 Bigham A.W....Brutsaert T.D. (amp 2008)
    750. Genetic risk factors for renal failure among north Indian ESRD patients. (PubMed id 18242170)1, 4 Tripathi G....Agrawal S. (Clin. Biochem. 2008)
    751. Angiotensin-converting enzyme gene polymorphism is associated with anemia in non small-cell lung cancer. (PubMed id 18156303)1, 4 Yaren A....Demirpence M. (Exp. Biol. Med. (Maywood) 2008)
    752. Renin-angiotensin system inhibitors, angiotensin I-converting enzyme gene insertion/deletion polymorphism, and cancer: the Rotterdam Study. (PubMed id 18181094)1, 4 van der Knaap R....Stricker B.H. (Cancer 2008)
    753. Male-female differences in the genetic regulation of t-PA and PAI-1 levels in a Ghanaian population. (PubMed id 18953568)1, 4 Schoenhard J.A....Williams S.M. (Hum. Genet. 2008)
    754. ACE insertion/deletion, but not -240A&gt;T polymorphism, modulates the severity in heart failure. (PubMed id 19050458)1, 4 Fatini C....Abbate R. (J. Investig. Med. 2008)
    755. Connection between genetically determined blood coagulation factors and haemorheology. (PubMed id 18503143)1, 4 PongrA!cz E....Nagy Z. (Clin. Hemorheol. Microcirc. 2008)
    756. Renin-angiotensin and endothelial nitric oxide synthase gene polymorphisms are not associated with the risk of incident type 2 diabetes mellitus: a prospective cohort study. (PubMed id 18069999)1, 4 Conen D....Zee R.Y. (J. Intern. Med. 2008)
    757. Polymorphisms of EDNRB, ATG, and ACE genes in salt-sensitive hypertension. (PubMed id 18758497)1, 4 Caprioli J....Benigni A. (Can. J. Physiol. Pharmacol. 2008)
    758. Angiotensin converting enzyme insertion/deletion genetic polymorphism: its impact on renal function in critically ill patients. (PubMed id 19020433)1, 4 du Cheyron D....Charbonneau P. (Crit. Care Med. 2008)
    759. Association of arterial stiffness with the angiotensin-converting enzyme gene polymorphism in healthy individuals. (PubMed id 18833197)1, 4 Dima I....Stefanadis C. (Am. J. Hypertens. 2008)
    760. Genetic variation and activity of the renin-angiotensin system and severe hypoglycemia in type 1 diabetes. (PubMed id 18328310)1, 4 Pedersen-Bjergaard U....Thorsteinsson B. (Am. J. Med. 2008)
    761. Gene-load score of the renin-angiotensin-aldosterone system is associated with coronary heart disease in familial hypercholesterolaemia. (PubMed id 18413308)1, 4 van der Net J.B....Sijbrands E.J. (Eur. Heart J. 2008)
    762. Relation between renin-angiotensin-aldosterone system and otosclerosis: a genetic association and in vitro study. (PubMed id 18491423)1, 4 Imauchi Y....Grayeli A.B. (amp 2008)
    763. Sex differences in environmental and genetic factors for hypertension. (PubMed id 18724972)1, 4 Ruixing Y....Yuming C. (Am. J. Med. 2008)
    764. Ten renin-angiotensin system-related gene polymorphisms in maximally treated Canadian Caucasian patients with heart failure. (PubMed id 18279468)1, 4 Zakrzewski-Jakubiak M....Turgeon J. (Br J Clin Pharmacol 2008)
    765. Interaction between polymorphisms in the renin-angiotensin-system and angiotensin-converting enzyme inhibitor or beta-blocker use and the risk of myocardial infarction and stroke. (PubMed id 18347611)1, 4 Schelleman H....Stricker B.H. (Pharmacogenomics J. 2008)
    766. Association of polymorphisms in the angiotensin-converting enzyme gene with syndromal panic attacks. (PubMed id 18285758)1, 4 Erhardt A....Holsboer F. (Mol. Psychiatry 2008)
    767. Homogeneous assay of rs4343, an ACE I/D proxy, and an analysis in the British Women's Heart and Health Study (BWHHS). (PubMed id 18057531)1, 4 Abdollahi M.R....Gaunt T.R. (Dis. Markers 2008)
    768. Interaction between angiotensin converting enzyme insertion/deletion genotype and exercise training on knee extensor strength in older individuals. (PubMed id 17614015)1, 4 Giaccaglia V....Pahor M. (Int J Sports Med 2008)
    769. Vitamin D receptor genotypes influence quadriceps strength in chronic obstructive pulmonary disease. (PubMed id 18258629)1, 4 Hopkinson N.S....Polkey M.I. (Am. J. Clin. Nutr. 2008)
    770. Angiotensin-converting enzyme insertion/deletion gene polymorphic variant as a marker of coronary artery disease: a meta-analysis. (PubMed id 18504336)1, 4 Zintzaras E....Lau J. (Arch. Intern. Med. 2008)
    771. Synergistic effect of the genetic polymorphisms of the renin-angiotensin-aldosterone system on high-altitude pulmonary edema: a study from Qinghai-Tibet altitude. (PubMed id 17987391)1, 4 Qi Y....Qiu C. (Eur. J. Epidemiol. 2008)
    772. Population-based case-control study of renin-angiotensin system genes polymorphisms and hypertension among Hispanics. (PubMed id 18497458)1, 4 Bautista L.E....Gamarra G. (Hypertens. Res. 2008)
    773. Angiotensin-converting enzyme insertion/deletion polymorphism and risk and outcome of pneumonia. (PubMed id 17908703)1, 4 van de Garde E.M....van den Bosch J.M. (Chest 2008)
    774. Association between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and erectile dysfunction in patients with metabolic syndrome. (PubMed id 17673929)1, 4 Mazo E.B....Iremashvili V.V. (Int. J. Impot. Res. 2008)
    775. Pharmacological effects of lipid-lowering drugs recapitulate with a larger amplitude the phenotypic effects of common variants within their target genes. (PubMed id 18787507)1, 4 Knouff C.W....Mooser V. (Pharmacogenet. Genomics 2008)
    776. Adaptation to high altitude in Sherpas: association with the insertion/deletion polymorphism in the Angiotensin-converting enzyme gene. (PubMed id 18333655)1, 4 Droma Y....Kubo K. (amp 2008)
    777. ACE I/D polymorphism and recurrent first trimester pregnancy loss: interaction with SERPINE1 4G/5G and F13 Val34Leu polymorphisms. (PubMed id 18318764)1, 4 Dossenbach-Glaninger A....Hopmeier P. (Br. J. Haematol. 2008)
    778. The relationship between angiotensin-converting enzyme insertion/deletion polymorphism and proliferative retinopathy in type 2 diabetes. (PubMed id 18541327)1, 4 Feghhi M....Rashidi A. (Diabetes Res. Clin. Pract. 2008)
    779. Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with metabolic syndrome in Iranians with type 2 diabetes mellitus. (PubMed id 18154415)1, 4 Nikzamir A....Dibai L. (Arch Iran Med 2008)
    780. Role of angiotensin-converting enzyme gene polymorphisms in children with sepsis and septic shock. (PubMed id 19143971)1, 4 Cogulu O....Ozkinay F. (Pediatr Int 2008)
    781. Human paraoxonase gene polymorphisms and coronary artery disease risk. (PubMed id 19280995)1, 4 MendonAsa M.I....Cardoso A.A. (Rev Port Cardiol 2008)
    782. [Association of alpha-adducin and angiotensin converting enzyme gene polymorphisms with salt-sensitive hypertension and early renal injury]. (PubMed id 18393230)1, 4 Lu L.H....Yu L. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2008)
    783. Angiotensin-converting enzyme gene polymorphism and coronary reactivity in young men. (PubMed id 17852816)1, 4 KAohAPnen M....Nieminen T. (Scand. J. Clin. Lab. Invest. 2007)
    784. Insertion/deletion polymorphism of the angiotensin I-converting enzyme gene in patients with breast cancer and effects on prognostic factors. (PubMed id 17850737)1, 4 Yaren A....Erdem E. (J. Investig. Med. 2007)
    785. Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals. (PubMed id 17455988)1, 4 Ariyaratnam R....Sharma P. (PLoS Med. 2007)
    786. Genetic polymorphisms contribute to acute kidney injury after coronary artery bypass grafting. (PubMed id 17921131)1, 4 Isbir S.C....Arsan S. (Heart Surg Forum 2007)
    787. Genetic polymorphism of the angiotensin converting enzyme and L-dopa-induced adverse effects in Parkinson's disease. (PubMed id 17196621)1, 4 Lin J.J....Liu J.T. (J. Neurol. Sci. 2007)
    788. Angiotensin-converting enzyme gene polymorphism in Kuwaiti patients with systemic lupus erythematosus. (PubMed id 17631741)1, 4 Al-Awadhi A.M....Al-Saeid K. (Clin. Exp. Rheumatol. 2007)
    789. Renin-angiotensin system haplotypes and the risk of myocardial infarction and stroke in pharmacologically treated hypertensive patients. (PubMed id 17522061)1, 4 Marciante K.D....Psaty B.M. (Am. J. Epidemiol. 2007)
    790. Combination of angiotensin-converting enzyme and methylenetetrahydrofolate reductase gene polymorphisms as determinant risk factors for chronic allograft dysfunction. (PubMed id 17275478)1, 4 de Alvarenga M.P....Goloni-Bertollo E.M. (Transplant. Proc. 2007)
    791. Relationship between angiotensin-converting enzyme gene polymorphism and severity of aortic valve calcification. (PubMed id 17673063)1, 4 Ertas F.S....Erol C. (Mayo Clin. Proc. 2007)
    792. The angiotensin-converting enzyme insertion/deletion polymorphism and serum levels of angiotensin-converting enzyme in venous thromboembolism. Data from a case control study. (PubMed id 17938801)1, 4 Ay C....Pabinger I. (Thromb. Haemost. 2007)
    793. Association between the insertion/deletion polymorphism of the angiotensin I-converting enzyme gene and risk for psoriasis in a Chinese population in Taiwan. (PubMed id 17263818)1, 4 Chang Y.C....Hsu L.A. (Br. J. Dermatol. 2007)
    794. Renin-angiotensin system gene polymorphisms and coronary artery disease in a large angiographic cohort: detection of high order gene-gene interaction. (PubMed id 17118372)1, 4 Tsai C.T....Tseng Y.Z. (Atherosclerosis 2007)
    795. [The role of angiotensin-converting enzyme and apolipoprotein E in the development of intracranial aneurysms.] (PubMed id 18477980)1, 4 Lebedeva E.R....Khusnutdinova E.K. (Zh Nevrol Psikhiatr Im S S Korsakova 2007)
    796. Combined effects of ACE and MMP-3 polymorphisms on migraine development. (PubMed id 17381556)1, 4 Kara I....Tireli H. (Cephalalgia 2007)
    797. [Endothelial function and I/D polymorphism of angiotensin converting enzyme gene in patients with essential hypertension]. (PubMed id 18260877)1, 4 Polupanov A.G....Dzhumagulova A.S. (Kardiologiia 2007)
    798. Allelic frequencies at the ACE and LRPAP1 loci suggest age-related relationships in a northern Italian population. (PubMed id 17536759)1, 4 Santovito A....Delpero M. (Ann. Hum. Biol. 2007)
    799. [Angiotensin-1 converting enzyme insertion/deletion gene polymorphism in a Mexican population with diabetic nephropathy]. (PubMed id 17570179)1, 4 Ortega-Pierres L.E....Alvarez-Aguilar C. (Med Clin (Barc) 2007)
    800. [Relationship between I/D polymorphism of angiotensin I converting enzyme gene and microvascular complications in type 2 diabetic patients]. (PubMed id 17941464)1, 4 Moleda P....Goracy I. (Prz. Lek. 2007)
    801. Reduced plasma levels of angiotensin-(1-7) and renin activity in preeclamptic patients are associated with the angiotensin I- converting enzyme deletion/deletion genotype. (PubMed id 17401503)1, 4 Velloso E.P....Santos R.A. (Braz. J. Med. Biol. Res. 2007)
    802. Angiotensin-converting-enzyme gene polymorphisms, smoking and chronic obstructive pulmonary disease. (PubMed id 18229571)1, 4 Busquets X....AgustA- A.G. (Int J Chron Obstruct Pulmon Dis 2007)
    803. Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension. (PubMed id 17334527)1, 4 Freitas S.R....Cordovil I.L. (Braz. J. Med. Biol. Res. 2007)
    804. Genetic polymorphisms of the renin-angiotensin system in preterm delivery and premature rupture of membranes. (PubMed id 18205094)1, 4 Valdez-Velazquez L.L....Rivas F. (J Renin Angiotensin Aldosterone Syst 2007)
    805. The angiotensin II/angiotensin II receptor system correlates with nodal spread in intestinal type gastric cancer. (PubMed id 17548686)1, 4 RAPcken C....Ebert M.P. (amp 2007)
    806. Combined analysis of genetic and environmental factors on essential hypertension in a brazilian rural population in the Amazon region. (PubMed id 17546276)1, 4 Freitas S.R....BA^ia M.N. (Arq. Bras. Cardiol. 2007)
    807. The frequency of angiotensin-converting enzyme genotype and left ventricular functions in the obese population. (PubMed id 18046090)1, 4 Bitigen A....Basaran Y. (Congest Heart Fail 2007)
    808. Angiotensin-converting enzyme insertion/deletion gene polymorphism in inflammatory bowel diseases. (PubMed id 18049167)1, 4 Saibeni S....Vecchi M. (amp 2007)
    809. [The insertion/deletion polymorphism (I/D) of the ACE gene in pregnant women with excessive weight gain]. (PubMed id 17915410)1, 4 Drews K....Kaluba-Skotarczak A. (Ginekol. Pol. 2007)
    810. Haplotype of growth hormone and angiotensin I-converting enzyme genes, serum angiotensin I-converting enzyme and ventricular growth: pathway inference in pharmacogenetics. (PubMed id 17496728)1, 4 Huang S....Gaunt T.R. (Pharmacogenet. Genomics 2007)
    811. Angiotensin-converting enzyme gene polymorphism in patients with psoriatic arthritis. (PubMed id 17440728)1, 4 Al-Awadhi A.M....Al-Saeid K. (Rheumatol. Int. 2007)
    812. The association of angiotensin converting enzyme (ACE) polymorphisms with sleep apnea and hypertension. (PubMed id 17520798)1, 4 Patel S.R....Redline S. (Sleep 2007)
    813. M235T polymorphism of the angiotensinogen gene and insertion/deletion polymorphism of the angiotensin-1 converting enzyme gene in essential arterial hypertension in Caucasians. (PubMed id 17448297)1, 4 Glavnik N. and Petrovic D. (Folia Biol. (Praha) 2007)
    814. A prospective evaluation of left ventricular remodeling after inaugural anterior myocardial infarction as a function of gene polymorphisms in the renin-angiotensin-aldosterone, adrenergic, and metalloproteinase systems. (PubMed id 17383306)1, 4 Bauters C....Amouyel P. (Am. Heart J. 2007)
    815. Significant association of insertion/deletion polymorphism of the angiotensin-converting enzyme gene with rheumatoid arthritis. (PubMed id 17985406)1, 4 Uppal S.S....Dhaunsi G.S. (J. Rheumatol. 2007)
    816. ACE and LRPAP1 insertion-deletion polymorphisms in a northern Ivory Coast population. (PubMed id 18494379)1, 4 Santovito A....Delpero M. (Hum. Biol. 2007)
    817. Renin-angiotensin-system gene polymorphisms and depression. (PubMed id 17499413)1, 4 Saab Y.B....Ingram M.J. (amp 2007)
    818. Genetic variation associated with ischemic heart failure: a HuGE review and meta-analysis. (PubMed id 17644825)1, 4 Kitsios G. and Zintzaras E. (Am. J. Epidemiol. 2007)
    819. The relationship between the insertion/deletion polymorphism of the ACE gene and hypertension in Iranian patients with type 2 diabetes. (PubMed id 17478487)1, 4 Nakhjavani M....Zahraei M. (Nephrol. Dial. Transplant. 2007)
    820. [Specifics of distribution of polymorphic markers of the renin-angiotensin-system genes, relation to ventricular hypertrophy in patients with essential hypertension of Uzbek nationality]. (PubMed id 18260840)1, 4 Khamidullaeva G.A....Abdullaeva G.Z.h. (Kardiologiia 2007)
    821. Disease progression, response to ACEI/ATRA therapy and influence of ACE gene in IgA nephritis. (PubMed id 17601378)1, 4 Woo K.T....Wong K.S. (amp 2007)
    822. Is the influence of variation in the ACE gene on the prospective risk of Type 2 diabetes in middle-aged men modified by obesity? (PubMed id 17624939)1, 4 Muthumala A....Humphries S.E. (Clin. Sci. 2007)
    823. Recurrent in-stent restenosis is not associated with the angiotensin-converting enzyme D/I, angiotensinogen Thr174Met and Met235Thr, and the angiotensin-II receptor 1 A1166C polymorphism. (PubMed id 17541127)1, 4 Gross C.M....Ozcelik C. (J Invasive Cardiol 2007)
    824. Synergistic effect of renin-angiotensin system and nitric oxide synthase genes polymorphisms in pre-eclampsia. (PubMed id 17520398)1, 4 Benedetto C....Stratta P. (Acta Obstet Gynecol Scand 2007)
    825. Interaction between GNB3 C825T and ACE I/D polymorphisms in essential hypertension in Koreans. (PubMed id 17066084)1, 4 Bae Y....Yoon S.K. (J Hum Hypertens 2007)
    826. Serological and genetic factors in early recurrence of IgA nephropathy after renal transplantation. (PubMed id 17988266)1, 4 Coppo R....Ponticelli C. (Clin Transplant 2007)
    827. The gene polymorphism of the angiotensin I-converting enzyme correlates with tumor size and patient survival in colorectal cancer patients. (PubMed id 17898867)1, 4 RAPcken C....Neumann U. (Neoplasia 2007)
    828. Gene polymorphism of angiotensin-converting enzyme and angiotensin II type 1 receptor in patients with congestive heart failure. (PubMed id 18767410)1, 4 Pop D....Popal A. (Rom J Intern Med 2007)
    829. D-allele of ACE polymorphism is associated with increased magnitude of QT dispersion prolongation in elderly Chinese: 4-year follow-up study. (PubMed id 17186976)1, 4 Lin T.H....Sheu S.H. (Circ. J. 2007)
    830. Genotype modulators of clinical severity in McArdle disease. (PubMed id 17630210)1, 4 Rubio J.C....Lucia A. (Neurosci. Lett. 2007)
    831. Sex-related influence of angiotensin-converting enzyme polymorphisms on fibrosis progression due to recurrent hepatitis C after liver transplantation. (PubMed id 17653650)1, 4 Fabris C....Pirisi M. (J. Gastroenterol. 2007)
    832. Renin-angiotensin system polymorphisms and renal graft function in renal transplant recipients. (PubMed id 17914507)1, 4 Argani H....Hamzeiy H. (Saudi Med J 2007)
    833. Sex-specific effects of AGT-6 and ACE I/D on pulse pressure after 6 months on antihypertensive treatment: the GenHAT study. (PubMed id 17608790)1, 4 Lynch A.I....Leiendecker-Foster C. (Ann. Hum. Genet. 2007)
    834. Angiotensin-converting enzyme genotype interacts with systolic blood pressure to determine coronary heart disease risk in healthy middle-aged men. (PubMed id 17562973)1, 4 Muthumala A....Humphries S.E. (Hypertension 2007)
    835. No association with risk for colorectal cancer of the insertion/deletion polymorphism which affects levels of angiotensin-converting enzyme. (PubMed id 18210757)1, 4 Nikiteas N....Yannopoulos A. (In Vivo 2007)
    836. Angiotensin-converting enzyme I/D polymorphism and macrovascular disease in systemic sclerosis. (PubMed id 17264090)1, 4 Bartoli F....Matucci Cerinic M. (Rheumatology (Oxford) 2007)
    837. Angiotensin-converting enzyme genotype and C-reactive protein in patients with COPD. (PubMed id 17400881)1, 4 Tkacova R. and Joppa P. (Eur. Respir. J. 2007)
    838. Gene polymorphisms predisposing to cardiac hypertrophy in patients with cardiac syndrome X. (PubMed id 19051693)1, 4 Jabrocka-Hybel A....DembiA8ska-KieA8 A. (Folia Med Cracov 2007)
    839. Angiotensin-converting enzyme gene 2350 G/A polymorphism is associated with left ventricular hypertrophy but not essential hypertension. (PubMed id 17460369)1, 4 Pan M....Yang X.J. (Hypertens. Res. 2007)
    840. The relationship between ACE genotype and risk of severe hypoglycaemia in a large population-based cohort of children and adolescents with type 1 diabetes. (PubMed id 17333108)1, 4 Bulsara M.K....Jones T.W. (Diabetologia 2007)
    841. Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with allergic contact dermatitis. (PubMed id 17651310)1, 4 Nacak M....Tiftik R.N. (amp 2007)
    842. Interaction between the angiotensin-converting enzyme gene insertion/deletion polymorphism and obstructive sleep apnoea as a mechanism for hypertension. (PubMed id 17351369)1, 4 BostrAPm K.B....Lindblad U. (J. Hypertens. 2007)
    843. Sex-specific effects of ACE I/D and AGT-M235T on pulse pressure: the HyperGEN Study. (PubMed id 17492314)1, 4 Lynch A.I....DjoussAc L. (Hum. Genet. 2007)
    844. The M235T polymorphism in the angiotensinogen gene is associated with the risk of malignant hypertension in white patients. (PubMed id 17921816)1, 4 van den Born B.J....Koopmans R.P. (J. Hypertens. 2007)
    845. Cardiovascular diseases and molecular variants of the renin-angiotensin system components in Slovak population. (PubMed id 17579251)1, 4 Jurkovicova D....Krizanova O. (Gen. Physiol. Biophys. 2007)
    846. Association between angiotensin-converting enzyme gene polymorphisms and diabetic nephropathy: case-control, haplotype, and family-based study in three European populations. (PubMed id 17376814)1, 4 Hadjadj S....Hager-Vionnet N. (J. Am. Soc. Nephrol. 2007)
    847. Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with increased risk for oral cancer. (PubMed id 17851834)1, 4 Vairaktaris E....Patsouris E. (Acta Oncol 2007)
    848. RAAS gene polymorphisms influence progression of pediatric hypertrophic cardiomyopathy. (PubMed id 17851694)1, 4 Kaufman B.D....Mital S. (Hum. Genet. 2007)
    849. ACE ID genotype affects blood creatine kinase response to eccentric exercise. (PubMed id 17885020)1, 4 Yamin C....Amir R.E. (J. Appl. Physiol. 2007)
    850. Relation of beta(2)-adrenoceptor haplotype to risk of death and heart transplantation in patients with heart failure. (PubMed id 17223428)1, 4 Shin J....Johnson J.A. (Am. J. Cardiol. 2007)
    851. Effect of renin-angiotensin-aldosterone system gene polymorphisms on blood pressure response to antihypertensive treatment. (PubMed id 17531119)1, 4 Jiang X....Zhan Y.Y. (Chin. Med. J. 2007)
    852. Angiotensin-converting enzyme genotype and successful ascent to extreme high altitude. (PubMed id 18081503)1, 4 Thompson J....Montgomery H. (amp 2007)
    853. Relationship between angiotensin-converting enzyme gene insertion or deletion polymorphism and insulin sensitivity in healthy newborns. (PubMed id 17545375)1, 4 Han T....Piao M. (Pediatrics 2007)
    854. Angiotensin converting enzyme insertion/deletion polymorphism in sporadic and familial Alzheimer's disease and longevity. (PubMed id 17182125)1, 4 Nacmias B....Sorbi S. (Arch Gerontol Geriatr 2007)
    855. ACE gene deletion/deletion polymorphism may be a protective factor for respiratory distress in preterm infants. (PubMed id 17479647)1, 4 Sivasli E....TA1kA1n A. (Turk. J. Pediatr. 2007)
    856. The angiotensin-converting enzyme insertion/deletion and the endothelin -134 3A/4A gene polymorphisms in patients with chronic plaque psoriasis. (PubMed id 18031458)1, 4 Weger W....Salmhofer W. (Exp. Dermatol. 2007)
    857. Angiotensin-converting enzyme gene polymorphism in North-west Indian children with posterior urethral valves. (PubMed id 18947757)1, 4 Narasimhan K.L....Kaur B. (J Pediatr Urol 2007)
    858. Epistatic effects of polymorphisms in genes from the renin-angiotensin, bradykinin, and fibrinolytic systems on plasma t-PA and PAI-1 levels. (PubMed id 17207964)1, 4 Asselbergs F.W....Moore J.H. (Genomics 2007)
    859. [Association between angiotensin-converting enzyme and endothelial nitric oxide synthase gene polymorphism and risk of coronary artery disease]. (PubMed id 18269824)1, 4 Ji X.W....Guan L.X. (Zhonghua Xin Xue Guan Bing Za Zhi 2007)
    860. Association between angiotensin-1 converting enzyme gene polymorphism and the metabolic syndrome in a Mexican population. (PubMed id 17603286)1, 4 Alvarez-Aguilar C....LA^pez-Meza J.E. (amp 2007)
    861. ACE I/D polymorphism study in a Cuban hypertensive population. (PubMed id 17196575)1, 4 Companioni NA!poles O....DueA+as M. ( international journal of clinical chemistry 2007)
    862. Low-responders to angiotensin II receptor blockers and genetic polymorphism in angiotensin-converting enzyme. (PubMed id 17969487)1, 4 Nonoguchi H....Tomita K. (Clin. Nephrol. 2007)
    863. Impact of maternal angiotensinogen M235T polymorphism and angiotensin-converting enzyme insertion/deletion polymorphism on blood pressure, protein excretion and fetal outcome in pregnancy. (PubMed id 17563539)1, 4 Pfab T....Hocher B. (J. Hypertens. 2007)
    864. Polymorphisms of angiotensinogen and angiotensin-converting enzyme associated with lower extremity arterial disease in the Health, Aging and Body Composition study. (PubMed id 17429448)1, 4 Li R....Kritchevsky S.B. (J Hum Hypertens 2007)
    865. Renin-angiotensin-aldosterone system polymorphisms: a role or a hole in occurrence and long-term prognosis of acute myocardial infarction at young age. (PubMed id 17519002)1, 4 Franco E....Bergerone S. (BMC Med. Genet. 2007)
    866. ACE I/D but not AGT (-6)A/G polymorphism is a risk factor for mortality in ARDS. (PubMed id 17107992)1, 4 Adamzik M....Siffert W. (Eur. Respir. J. 2007)
    867. Gene polymorphisms of the renin-angiotensin-aldosterone system and angiotensin II type 1-receptor activating antibodies in renal rejection. (PubMed id 17984617)1, 4 Zhang G....Zhang R. (Tohoku J. Exp. Med. 2007)
    868. Impact of renin-angiotensin-aldosterone system genes on the treatment response of patients with hypertension and metabolic syndrome. (PubMed id 18205097)1, 4 Milionis H.J....Siamopoulos K.C. (J Renin Angiotensin Aldosterone Syst 2007)
    869. Susceptibility groups for Alzheimer's disease (OPTIMA cohort): integration of gene variants and biochemical factors. (PubMed id 17116317)1, 4 Corder E.H. and Beaumont H. (Mech. Ageing Dev. 2007)
    870. Polymorphisms in the angiotensin converting enzyme gene and growth in the first year of life. (PubMed id 17032288)1, 4 Hindmarsh P.C....Humphries S.E. (Ann. Hum. Genet. 2007)
    871. Association between functional polymorphisms of renin-angiotensin system, left ventricular mass, and geometry over 4 years in a healthy Chinese population aged 60 years and older. (PubMed id 17921431)1, 4 Lin T.H....Sheu S.H. (J. Gerontol. A Biol. Sci. Med. Sci. 2007)
    872. No contribution of angiotensin-converting enzyme (ACE) gene variants to severe obesity: a model for comprehensive case/control and quantitative cladistic analysis of ACE in human diseases. (PubMed id 17164796)1, 4 Bell C.G....Walley A.J. (Eur. J. Hum. Genet. 2007)
    873. Candidate genetic risk factors of stroke: results of a multilocus genotyping assay. (PubMed id 17317888)1, 4 Lalouschek W....Mannhalter C. (Clin. Chem. 2007)
    874. Lone and secondary nonvalvular atrial fibrillation: role of a genetic susceptibility. (PubMed id 17113662)1, 4 Fatini C....Gensini G.F. (Int. J. Cardiol. 2007)
    875. Do angiotensin-converting enzyme (ACE) inhibitors enhance the effect of exercise rehabilitation in patients with hypertension and ACE DD and DI genotypes? (PubMed id 17270528)1, 4 Duzli Y....Ben-Dov I. (Arch Phys Med Rehabil 2007)
    876. Effects of ACE I/D polymorphism on prostate cancer risk, tumor grade and metastatis. (PubMed id 17465223)1, 4 Yigit B....Isbir T. (Anticancer Res. 2007)
    877. Prolylcarboxypeptidase gene, chronic hypertension, and risk of preeclampsia. (PubMed id 16681991)1, 4 Wang L....Wang X. (Am. J. Obstet. Gynecol. 2006)
    878. [Polymorphism I/D of the angiotensin-converting enzyme gene and disturbance of blood pressure in type 1 diabetic children and adolescents]. (PubMed id 16898483)1, 4 Szadkowska A....Bodalski J. (Prz. Lek. 2006)
    879. Genetic variation in the renin-angiotensin system and autonomic nervous system function in young healthy Japanese subjects. (PubMed id 16954165)1, 4 Nishikino M....Aoki N. (J. Clin. Endocrinol. Metab. 2006)
    880. Association of angiotensin converting enzyme gene I/D polymorphism with type 2 diabetes mellitus. (PubMed id 17044652)1, 4 Yang M....Xiang H.D. (Biomed. Environ. Sci. 2006)
    881. Polymorphism of the angiotensin-converting enzyme gene affects the outcome of acute respiratory distress syndrome. (PubMed id 16484896)1, 4 Jerng J.S....Yang P.C. (Crit. Care Med. 2006)
    882. Genetic and environmental factors associated with the development of hypertension in pregnancy. (PubMed id 16369102)1, 4 Kobashi G. (J Epidemiol 2006)
    883. Gene polymorphisms in patients below 35 years of age who underwent coronary artery bypass surgery. (PubMed id 16374139)1, 4 TA1tA1n U....KatircioA9lu S.F. (Coron. Artery Dis. 2006)
    884. [Pharmacogenetics of chronic heart failure--beta blockers]. (PubMed id 16521406)1, 4 VaskA^ A....VA-tovec J. (Cas. Lek. Cesk. 2006)
    885. Genetic polymorphisms of the renin-angiotensin system in end-stage renal disease. (PubMed id 16384824)1, 4 Buraczynska M....Ksiazek A. (Nephrol. Dial. Transplant. 2006)
    886. Polymorphism of the renin-angiotensin-aldosterone system in patients with chronic allograft dysfunction. (PubMed id 16635753)1, 4 Ayed K.h....Kheder A. (Transpl. Immunol. 2006)
    887. Angiotensin-converting enzyme DD genotype is preventive against circulatory failure in very-low-birthweight neonates. (PubMed id 16754559)1, 4 Nobilis A....VA!sA!rhelyi B. (Acta Paediatr. 2006)
    888. Aldosterone synthase -344C/T and angiotensin-converting enzyme I/D polymorphisms in Turkish hypertensive patients with normal coronary arteries. (PubMed id 16485730)1, 4 Olcay A....Ozbek U. (Acta Cardiol 2006)
    889. Identifying genetic susceptibilities to diabetes-related complications among individuals at low risk of complications: An application of tree-structured survival analysis. (PubMed id 16928730)1, 4 Costacou T....Orchard T.J. (Am. J. Epidemiol. 2006)
    890. Gene polymorphisms of the renin-angiotensin system and early development of hypertension. (PubMed id 16876684)1, 4 BarbaliA8 M....NaranciA8 N.S. (Am. J. Hypertens. 2006)
    891. Endothelial nitric oxide synthase gene influences the risk of pre-eclampsia, the recurrence of negative pregnancy events, and the maternal-fetal flow. (PubMed id 16915032)1, 4 Fatini C....Abbate R. (J. Hypertens. 2006)
    892. Angiotensin-converting enzyme (ACE) inhibition in type 2, diabetic patients-- interaction with ACE insertion/deletion polymorphism. (PubMed id 16395257)1, 4 So W.Y....Chan J.C. (Kidney Int. 2006)
    893. Crystal structure of the N domain of human somatic angiotensin I- converting enzyme provides a structural basis for domain-specific inhibitor design. (PubMed id 16476442)1, 2 Corradi H.R....Acharya K.R. (J. Mol. Biol. 2006)
    894. Gene polymorphisms implicated in influencing susceptibility to venous and arterial thromboembolism: frequency distribution in a healthy German population. (PubMed id 17003923)1, 4 Hoppe B....Salama A. (Thromb. Haemost. 2006)
    895. Association between angiotensin-converting enzyme gene polymorphism and childhood allergic rhinitis in Taiwan. (PubMed id 16926975)1, 4 Ku M.S....Chou M.C. (J Microbiol Immunol Infect 2006)
    896. Relationship of ENOS and RAS gene polymorphisms to initial peritoneal transport status in peritoneal dialysis patients. (PubMed id 16741369)1, 4 Akcay A....Ozdemir F.N. (Nephron Clin Pract 2006)
    897. Influence of Angiotensin-converting enzyme polymorphism on neuropsychological subacute performance in moderate and severe traumatic brain injury. (PubMed id 16525069)1, 4 Ariza M....Sahuquillo J. (J Neuropsychiatry Clin Neurosci 2006)
    898. An angiotensin converting enzyme haplotype predicts survival in patients with end stage renal disease. (PubMed id 16791616)1, 4 Wetmore J.B....Lovett D.H. (Hum. Genet. 2006)
    899. Chronic renal insufficiency among Asian Indians with type 2 diabetes: I. Role of RAAS gene polymorphisms. (PubMed id 16672053)1, 4 Prasad P....Thelma B.K. (BMC Med. Genet. 2006)
    900. Genotype combinations of plasminogen activator inhibitor-1 and angiotensin-converting enzyme genes and risk for early onset of coronary heart disease. (PubMed id 16926677)1, 4 Loew M....Rothenbacher D. (amp 2006)
    901. Angiotensin-converting enzyme I/D gene polymorphism and risk of multiple sclerosis. (PubMed id 17083336)1, 4 LovreciA8 L....Peterlin B. (Acta Neurol. Scand. 2006)
    902. Lack of significant association of an insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene with tropical calcific pancreatitis. (PubMed id 17163998)1, 4 Bhaskar S....Chandak G.R. (BMC Gastroenterol 2006)
    903. Coexistence of angiotensin II type-1 receptor A1166C and angiotensin-converting enzyme D/D polymorphism suggests susceptibility for small-vessel-associated ischemic stroke. (PubMed id 16775386)1, 4 Szolnoki Z....Melegh B. (Neuromolecular Med. 2006)
    904. Genotype-corrected reference values for serum angiotensin-converting enzyme. (PubMed id 17138677)1, 4 Biller H....MA1ller-Quernheim J. (Eur. Respir. J. 2006)
    905. Association between the polymorphism of the angiotensin-converting enzyme gene and tumor size of breast cancer in premenopausal patients. (PubMed id 17023764)1, 4 Yaren A....Erdem E. (Tohoku J. Exp. Med. 2006)
    906. Angiotensin-converting enzyme genotype predicts cardiac and autonomic responses to prolonged exercise. (PubMed id 16875979)1, 4 Ashley E.A....Douglas P. (J. Am. Coll. Cardiol. 2006)
    907. Association of APOE (Hha1) and ACE (I/D) gene polymorphisms with type 2 diabetes mellitus in North West India. (PubMed id 16621107)1, 4 Singh P.P....Mastana S. (Diabetes Res. Clin. Pract. 2006)
    908. Variation in the lipoprotein lipase gene influences exercise-induced left ventricular growth. (PubMed id 16416313)1, 4 Flavell D.M....Montgomery H.E. (J. Mol. Med. 2006)
    909. [Insertion-deletion polymorphism in the gene for angiotensin-converning enzyme (I/D ACE) in pregnant women with gestational diabetes]. (PubMed id 17131920)1, 4 DostA!lovA! Z....Unzeitig V. (Ceska Gynekol 2006)
    910. Multi-locus candidate gene polymorphisms and risk of myocardial infarction: a population-based, prospective genetic analysis. (PubMed id 16420563)1, 4 Zee R.Y....Ridker P.M. (J. Thromb. Haemost. 2006)
    911. Common polymorphisms and cardiovascular factors in patients with myocardial infarction of Costa Rica. (PubMed id 18457169)1, 4 Salazar-SA!nchez L....Herrmann F.H. (Rev. Biol. Trop. 2006)
    912. +9/+9 Homozygosity of the bradykinin receptor gene polymorphism is associated with reduced fat-free mass in chronic obstructive pulmonary disease. (PubMed id 16600946)1, 4 Hopkinson N.S....Polkey M.I. (Am. J. Clin. Nutr. 2006)
    913. [The association of gene polymorphisms with the muscle fiber type composition]. (PubMed id 17300045)1, 4 Akhmetov I.I....Rogozkin V.A. (Ross Fiziol Zh Im I M Sechenova 2006)
    914. [Possible correlation of polymorphism of angiotensin-converting enzyme gene with psychological aspects of birth stress]. (PubMed id 17162847)1, 4 Spivak I.M....Spivak D.L. (Tsitologiia 2006)
    915. Association studies of genetic polymorphism, environmental factors and their interaction in ischemic stroke. (PubMed id 16443328)1, 4 Gao X....ZhiPing T. (Neurosci. Lett. 2006)
    916. ACE gene polymorphism might disclose why some Taiwanese children with allergic rhinitis develop asthma symptoms but others do not. (PubMed id 17014625)1, 4 Lue K.H....Chou M.C. (Pediatr Allergy Immunol 2006)
    917. The insertion polymorphism in angiotensin-converting enzyme gene associated with the APOE epsilon 4 allele increases the risk of late-onset Alzheimer disease. (PubMed id 17401152)1, 4 Wang B....Wang L. (J. Mol. Neurosci. 2006)
    918. Are the angiotensin-converting enzyme gene and activity risk factors for stroke? (PubMed id 16791358)1, 4 Dikmen M....Basaran A. (Arq Neuropsiquiatr 2006)
    919. Association between a functional polymorphism in the renin-angiotensin system and completed suicide. (PubMed id 16736244)1, 4 Hishimoto A....Maeda K. (J Neural Transm 2006)
    920. Angiotensin-converting enzyme insertion/deletion polymorphism and retinal artery occlusion. (PubMed id 16704688)1, 4 SchAofer E....Haas A. (Acta Ophthalmol Scand 2006)
    921. Drug-gene interaction between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and antihypertensive therapy. (PubMed id 16449550)1, 4 Schelleman H....Stricker B.H. (Ann Pharmacother 2006)
    922. Interaction of angiotensin I-converting enzyme insertion-deletion polymorphism and daily salt intake influences hypertension in Japanese men. (PubMed id 17283861)1, 4 Zhang L....Muramatsu M. (Hypertens. Res. 2006)
    923. Candidate gene polymorphism in cardiovascular disease: the BIP cohort. (PubMed id 16544732)1, 4 Leshinsky-Silver E....Zimlichman R. (Isr. Med. Assoc. J. 2006)
    924. [ACE gene polymorphism correlation (I/D) with the ventricular function in patients with ischemic and idiopathic dilated cardiomyopathy]. (PubMed id 16789598)1, 4 Avila-Vanzzini N....Herrera-Bello H. ( organo del Hospital de Enfermedades de la Nutrición 2006)
    925. Risk factor interactions and genetic effects associated with post-operative atrial fibrillation. (PubMed id 17094271)1, 4 Motsinger A.A....Ritchie M.D. (Pac Symp Biocomput 2006)
    926. Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: evidence of small-study bias. (PubMed id 17194198)1, 4 Serrano N.C....Casas J.P. (PLoS Med. 2006)
    927. Renin-angiotensin system genes and exercise training-induced changes in sodium excretion in African American hypertensives. (PubMed id 16937603)1, 4 Jones J.M....Brown M. (amp 2006)
    928. Angiotensin-converting enzyme insertion/deletion polymorphism and systemic lupus erythematosus: a metaanalysis. (PubMed id 16583472)1, 4 Lee Y.H....Song G.G. (J. Rheumatol. 2006)
    929. [An association study between the insertion/deletion polymorphism of angiotensin I converting enzyme gene and human speed endurance]. (PubMed id 17121351)1, 4 Liu T. and Sun X. (Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2006)
    930. Effect of angiotensin converting enzyme inhibitors on 1.25-(OH)2 D levels of hypertensive patients. Relationship with ACE polymorphisms. (PubMed id 17163356)1, 4 PAcrez-CastrillA^n J.L....DueA+as A. (Horm. Metab. Res. 2006)
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