ACE Gene
protein-coding GIFtS : 71
GCID: GC17 P061554
angiotensin I converting enzyme (peptidyl-dipeptidase A)... (Previous symbol: DCP1 )
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Aliasesfor ACE gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 1 2 Angiotensin Converting Enzyme, Somatic Isoform2 DCP11 2 3 5 Angiotensin I Converting Enzyme Peptidyl-Dipeptidase A 1 Transcript2 ACE11 2 5 Angiotensin-Converting Enzyme2 CD1431 2 Carboxycathepsin1 Dipeptidyl Carboxypeptidase I2 3 Dipeptidyl Carboxypeptidase 12 Kininase II2 3 Peptidase P2 DCP2 3 Testicular ECA2 CD143 Antigen2 3 EC 3.2.1.-3 MVCD32 5 EC 3.4.15.13 ICH2
Export aliases for ACE gene to outside databases Previous GC identifers: GC17P061205 GC17P063980 GC17P061895 GC17P062027 GC17P058908 GC17P056922
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Summariesfor ACE gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for ACE : This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. (provided by RefSeq, May 2010) UniProtKB/Swiss-Prot: ACE_HUMAN, P12821 Function : Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase ofthe vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety summary
for ACE : Angiotensin-converting enzyme (ACE, aka peptidyl dipeptidase A, carboxycathepsin) cleaves a C-terminaldipeptide from angiotensin I to create the vasoconstrictor peptide, angiotensin II. ACE can also inactivatethe vasodilator peptide, bradykinin. There are two isoforms of ACE, a smaller/single catalytic site enzymefound in the testes and a more widely expressed ~180kDa dual active site isoform. ACE is often membranebound. In contrast to ACE, the homolog ACE2, has recently been shown to cleave and inactivate angiotensin IIto generate the vasodilator Angiotensin (1-7). ACE inhibitors are widely used to treat hypertension andcardiovascular diseases. ACE inhibitors have also been used to slow nephropathy, particularly when it isassociated with diabetes. Gene Wiki entry for ACE (Angiotensin-converting enzyme) PharmGKB "VIP " summary for
ACE
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Viewsfor ACE gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000017.10 NC_018928.1 NT_010783.15 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ACE gene promoter: Sp1 GR-alpha Other transcription factors Search SABiosciences Chromatin IP Primers for ACE Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat ACE
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 17q23.3 Ensembl cytogenetic band: 17q23.3 HGNC cytogenetic band: 17q23.3 ACE Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 17 GeneLoc Exon Structure
GeneLoc location for GC17P061554: view genomic region
(about GC identifiers )
Start:
61,554,422 bp from pter
End:
61,599,205 bp from pter
Size:
44,784 bases
Orientation:
plus strand
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Proteinsfor ACE gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: ACE_HUMAN, P12821 (See
protein sequence )Recommended Name: Angiotensin-converting enzyme precursor Size : 1306 amino acids; 149715 Da
Cofactor : Binds 2 zinc ions per subunit. Isoform Testis-specific only binds 1 zinc ion per subunit
Cofactor : Binds 3 chloride ions per subunit
Subcellular location : Angiotensin-converting enzyme, soluble form: Secreted
Subcellular location : Cell membrane; Single-pass type I membrane protein
Miscellaneous : Inhibitors of ACE are commonly used to treat hypertension and some types of renal and cardiacdysfunction
Miscellaneous : The glycosidase activity probably uses different active site residues than the metalloprotease activity
Sequence caution : Sequence=BAD92208.1; Type=Erroneous initiation;
6/18 PDB 3D structures from and Proteopedia for ACE (see all 18 ):1O86 (3D)
  1O8A (3D)
  1UZE (3D)
  1UZF (3D)
  2C6F (3D)
  2C6N (3D)
 
Secondary accessions : B0LPF0 B4DXI3 E7EU16 P22966 Q53YX9 Q59GY8 Q7M4L4Alternative splicing : 4 isoforms : P12821-1 P12821-2 P12821-3, P22966-1 P12821-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ACE: NX_P12821 Post-translational modifications:
Phosphorylated by CK2 on Ser-1299; which allows membrane retention1
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_P12821 ACE Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (3 alternative transcripts):
NP_000780.1 NP_001171528.1 NP_690043.1 ENSEMBL proteins: ENSP00000462995 ENSP00000290866 ENSP00000462280 ENSP00000463302 ENSP00000463673 ENSP00000290863 ENSP00000462002 ENSP00000462110 ENSP00000392247 ENSP00000462599 ENSP00000464629 ENSP00000462909 ENSP00000464428 ENSP00000397593 ENSP00000439591 ENSP00000464539 ENSP00000387760 Reactome Protein details: P12821 Human Recombinant Protein Products: Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7 ): About this table
ACE for ontologies About GeneDecksing ACE Antibody Products: Assay Products for ACE:
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Protein
Domains / Familiesfor ACE gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
ACE for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry P12821 ProtoNet protein and cluster: P12821
1 Blocks protein family : IPB001548 Peptidyl-dipeptidase A (M2) metalloprotease family signature UniProtKB/Swiss-Prot: ACE_HUMAN, P12821 Similarity : Belongs to the peptidase M2 family
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Functionfor ACE gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: ACE_HUMAN, P12821 Function : Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase ofthe vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety Catalytic activity : Release of a C-terminal dipeptide, oligopeptide- -Xaa-Yaa, when Xaa is not Pro, and Yaa is neitherAsp nor Glu. Thus, conversion of angiotensin I to angiotensin II, with increase in vasoconstrictor activity, but no action on angiotensin II Enzyme regulation : Strongly activated by chloride. Specifically inhibited by lisinopril, captopril and enalaprilatBiophysicochemical properties : Kinetic parameters: KM=2.51 mM for Hip-His-Leu;Induction : Up-regulated in failing heartEnzyme Numbers (IUBMB): EC 3.2.1.- 1 EC 3.4.15.1 1
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ACE (see all 7 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ACE (see all 4 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): ACE (NM_000789 ) Sino Biological Human cDNA Clone for ACE DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACE Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ACE
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACE
Gene Ontology (GO): 5/11 molecular function terms (GO ID links to tree view) (see all 11 ): About this table
ACE for ontologies About GeneDecksing 1 GenomeRNAi human phenotype for ACE :Animal Models: Mouse knock-outs for ACE: Ace tm1Mcf Ace tm1Unc Ace tm2Unc Ace tm1Keb Ace tm4Keb Ace tm2Keb 14 MGI mutant phenotypes (inferred from 14 alleles ) (MGI details for Ace) :
ACE for phenotypes About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Pathways & Interactionsfor ACE gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways  - 5/9 super-pathways (see all 9 ) About this table See pathways by source Super-pathway contained gene-specific pathways 1 Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics 2 Renin-angiotensin system 3 Transcription_CREM signaling in testis 4 A-beta Uptake & Degradation 5 Hypertrophic cardiomyopathy (HCM)
Pathway sources See GeneCards unified pathways Show all pathways 1 R&D Systems Pathway for ACE 1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for ACE 1 GeneGo (Thomson Reuters) Pathway for ACE 1 BioSystems Pathway for ACE 3
Reactome Pathways for ACE 2 PharmGKB Pathways for ACE 3
Kegg Pathways (Kegg details for ACE) :
ACE for pathways About GeneDecksing Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ACE STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)5/6 Interacting proteins for ACE (P12821 3 ENSP00000290866 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 6 )About this table Gene Ontology (GO): 5/26 biological process terms (GO ID links to tree view) (see all 26 ): About this table
ACE for ontologies About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Drugs & Compoundsfor ACE gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section
ACE for compounds About GeneDecksing
Enzo Life Sciences drugs & compounds for ACE
Compounds for ACE available from Tocris Bioscience About this table 5 HMDB Compounds for ACE About this table 10/16 DrugBank Compounds for ACE (see all 16 ) About this table 10/127 Novoseek chemical compound relationships for ACE gene (see all 127 ) About this table
Compound
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
enalapril
93.5
720
7742150 (6), 11205963 (5), 1330361 (4), 9723634 (4) (see all 99 )
captopril
92.7
883
1847704 (5), 16394648 (5), 1330361 (4), 8074019 (4) (see all 99 )
lisinopril
92.4
420
9061270 (4), 1327597 (4), 8891468 (4), 18483087 (4) (see all 99 )
ramipril
91.6
389
12423701 (4), 1837563 (3), 1725019 (3), 12639174 (3) (see all 99 )
perindopril
90.3
384
9236432 (6), 1327597 (5), 19379059 (5), 10800878 (4) (see all 99 )
fosinopril
88.4
164
1646240 (4), 7919557 (3), 8861547 (3), 8934359 (3) (see all 98 )
quinapril
88.3
255
7527326 (7), 9049577 (5), 10024837 (4), 2068835 (4) (see all 99 )
enalaprilat
88.2
223
10082496 (4), 9815869 (4), 11827728 (3), 1656995 (3) (see all 99 )
trandolapril
86.4
138
7527095 (5), 9829159 (4), 12669106 (3), 17711535 (3) (see all 93 )
cilazapril
85.9
145
7614501 (4), 11108164 (4), 1689417 (3), 2139303 (3) (see all 97 )
3 PharmGKB related drug/compound annotations for ACE gene About this table Search CenterWatch for drugs/clinical trials and news about ACE
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Transcriptsfor ACE gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for ACE gene (4 alternative transcripts): NM_000789.3 NM_001178057.1 NM_152830.2 NM_152831.1 Unigene Cluster for ACE:
Angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 Hs.298469 [show with all ESTs ] Unigene Representative Sequence: JQ927553 18/25 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25 ): ENST00000583336 ENST00000584529 ENST00000582678 (uc010ddu.2 ) ENST00000579462 (uc010wph.2 )ENST00000290866 (uc002jau.2 ) ENST00000582627 ENST00000580318 ENST00000579726 ENST00000290863 (uc002jav.2 uc010wpj.2 uc010wpk.2 ) ENST00000582005 ENST00000578839 ENST00000413513 ENST00000579314 (uc010ddv.2 ) ENST00000579204 ENST00000584865 ENST00000582761 ENST00000577418 ENST00000583645 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ACE (see all 7 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ACE (see all 4 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): ACE (NM_000789 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACE Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ACE
Additional cDNA sequence: AB208971.1 AK296566.1 AK301988.1 J04144.1 JQ927553.1 M26657.1 S81361.1 X16295.1
13 DOTS entries : DT.450544 DT.95220519
DT.100790782 DT.75103816 DT.100790780 DT.86854701 DT.100790785 DT.95220571 DT.100770455 DT.100776952 DT.40116291 DT.95220617 DT.95322212 24/223 AceView cDNA sequences (see all 223 ):
NM_152831 BQ881320 BE382576 CD364763 BF196049 BI831717 BX380082 AI096704 NM_000789 BG152896 BE783248 H27155 BE464066 AW003214 AI371868 AW772527 BQ020350 AW772446 BM712523 J04144 BM984583 BF475825 BI826471 NM_152830 GeneLoc Exon Structure 5/14 Alternative Splicing Database (ASD) splice patterns (SP) for ACE (see all 14 ) About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b · 15c · 15d ^ 16a · 16b ^ 17 ^ 18a · 18b ^ SP1 :   -     -                             -   -   -   -     -   -     -   SP2 :                                             -   -     -   SP3 :                                             -   -     -   SP4 :                                         -     -   -     -   SP5 :                                             -   -      
ExUns: 19a · 19b · 19c ^ 20a · 20b ^ 21 ^ 22 ^ 23a · 23b ^ 24 ^ 25a · 25b ^ 26 ^ 27 ^ 28 ^ 29a · 29b SP1 : -       -               -               SP2 : -       -               -               SP3 : -                     -               SP4 : -       -                             SP5 : -       -                            
ECgene alternative splicing isoforms for ACE
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Expression for ACE gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ACE expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GGGAGAAGCT
About this image ACE expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See ACE Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ACE SOURCE GeneReport for Unigene cluster: Hs.298469 UniProtKB/Swiss-Prot: ACE_HUMAN, P12821 Tissue specificity : Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system andprostate. Isoform Testis-specific is expressed in spermatocytes and adult testis SABiosciences Expression via Pathway-Focused PCR Arrays including ACE : Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for ACEBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat ACE QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ACE QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ACE In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACE
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Orthologsfor ACE gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for ACE gene from 5/19 species (see all 19 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
ACE1
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 less
70.99(n) 68.28(a)
 
419953 NM_001167732.1 NP_001161204.1
lizard (Anolis carolinensis)
Reptilia
ACE6
--
64(a)
1 → many
6(61166678-61223235)
tropical clawed frog (Xenopus tropicalis)
Amphibia
Str.57762
Transcribed sequence with weak similarity to protein spP22966 (H.sapiens) ACET_HUMAN Angiotensin-converting enzyme, testis-specific isoform precursor (ACE-T) (Dipeptidyl carboxypeptidase I) (Kininase II) less
77.22(n)
 
BQ526772.1
zebrafish (Danio rerio)
Actinopterygii
ace1
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 less
67.07(n) 65.7(a)
 
565980 XM_689244.5 XP_694336.5
fruit fly (Drosophila melanogaster)
Insecta
Ance3
peptidyl-dipeptidase A
44(a) (best of 6)
 
2 34E2 --
ENSEMBL Gene Tree for ACE (if available)TreeFam Gene Tree for ACE (if available)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Paralogsfor ACE gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for ACE gene TMEM27 2 ENSG00000264813 2 ACE2 2 1 SIMAP similar gene for ACE using alignment to 21 protein entries: ACE_HUMAN (see all proteins ):ACE2
ACE for paralogs About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Variantsfor ACE gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 17 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for ACE (61554422 - 61599205 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for ACE 1 CNV : 10518 Human Gene Mutation Database (HGMD) : ACE SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ACE
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Disorders
/ Diseasesfor ACE gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
ACE for disorders About GeneDecksing OMIM gene information: 106180 OMIM disorders : 104300 612624 267430 UniProtKB/Swiss-Prot: ACE_HUMAN, P12821
Genetic variations in ACE may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors Defects in ACE are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype) Genetic variations in ACE are associated with susceptibility to microvascular complications of diabetes type 3 (MVCD3) [MIM:612624]. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis Defects in ACE are a cause of susceptibility to intracerebral hemorrhage (ICH) [MIM:614519]. A pathological condition characterized by bleeding into one or both cerebral hemispheres including the basal ganglia and the cerebral cortex. It is often associated with hypertension and craniocerebral trauma. Intracerebral bleeding is a common cause of stroke 20/377 diseases for ACE (see all 377 ): About MalaCards angiotensin i-converting enzyme, benign serum increase hypertension carotid intimal medial thickness nephropathy open-angle glaucoma novelty seeking personality aldosteronism arrhythmogenic right ventricular dysplasia sprinting performance hyporeninemic hypoaldosteronism renal tubular dysgenesis normal pressure hydrocephalus steroid-resistant nephrotic syndrome high blood pressure cough variant asthma arterial calcification of infancy generalized arterial calcification of infancy myocardial infarction microvascular complications of diabetes 3 mitral valve prolapse 20/23 diseases from the University of Copenhagen DISEASES database for ACE (see all 23 ):Hypertension Heart disease Proteinuria Diabetes mellitus Sarcoidosis Kidney failure Cerebrovascular accident Urticaria Atherosclerosis Nephritis Lung disease Renal vascular disease Nephrotic syndrome Hyperglycemia Systemic scleroderma Diabetic retinopathy Anemia Anuria Hypokalemia Oligohydramnios 10/97 Novoseek disease relationships for ACE gene (see all 97 ) About this table
Disease
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
heart failure
90.4
2092
11835905 (6), 14622625 (6), 16285075 (6), 11723314 (5) (see all 99 )
diabetic nephropathies
86.7
543
19077419 (7), 12016801 (6), 10332539 (5), 9111155 (4) (see all 99 )
essential hypertension
86.5
448
8686957 (4), 9626985 (4), 8076423 (3), 16866021 (3) (see all 99 )
heart failure congestive
86.2
526
8682064 (4), 18458262 (4), 8863101 (3), 7527326 (3) (see all 99 )
renal disease
85.5
960
17506717 (6), 11258145 (5), 12501871 (5), 12570791 (5) (see all 99 )
proteinuria
83.4
467
17984482 (5), 9328608 (4), 9767545 (4), 11007831 (4) (see all 99 )
microalbuminuria
83.1
234
15944842 (7), 15449965 (5), 19720797 (4), 16095545 (4) (see all 99 )
myocardial infarction
82.6
869
10462466 (7), 7606755 (7), 9812182 (5), 8644984 (5) (see all 99 )
angioedema
82.6
431
15111379 (8), 17540310 (7), 10594491 (7), 9530537 (7) (see all 99 )
ventricular dysfunction left
82.5
278
10499559 (4), 8994996 (3), 8095738 (3), 8682064 (3) (see all 99 )
Genetic Association Database (GAD): ACE Human Genome Epidemiology (HuGE) Navigator: ACE (1727 documents) Export disorders for ACE gene to outside databases
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Publicationsfor ACE gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ACE gene, integrated from 9 sources (see all 7503 ) (see top 10 ): (articles sorted by number of sources associating them with ACE) Utopia : connect your pdf to the dynamic world of online information
Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme. (PubMed id 15236580) 1 , 2 , 7, 9 Natesh R.... Acharya K.R. (2004) Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. (PubMed id 15534175) 1 , 2 , 4 Casas J.P.... Sharma P. (2004) Sequence variation in the human angiotensin converting enzyme. (PubMed id 10319862) 1 , 2 , 3 Rieder M.J.... Nickerson D.A. (1999) Molecular cloning of human testicular angiotensin-converting enzyme: the testis isozyme is identical to the C-terminal half of endothelial angiotensin-converting enzyme. (PubMed id 2554286) 1 , 2 , 3 Ehlers M.R.W.... Riordan J.F. (1989) Shedding of somatic angiotensin-converting enzyme (ACE) is inefficient compared with testis ACE despite cleavage at identical stalk sites. (PubMed id 10769174) 1 , 2 , 9 Woodman Z.L.... Sturrock E.D. (2000) CK2 phosphorylates the angiotensin-converting enzyme and regulates its retention in the endothelial cell plasma membrane. (PubMed id 12386153) 1 , 2 , 9 Kohlstedt K.... Fleming I. (2002) Neutral endopeptidase and angiotensin I converting enzyme insertion/deletion gene polymorphism in humans. (PubMed id 14730327) 1 , 4, 9 Jalil J.E....Lavandero S. (2004) Hypertension after renal transplantation and polymorphism of genes involved in essential hypertension: ACE, AGT, AT1 R and ecNOS. (PubMed id 11926202) 1 , 4, 9 Basset e.l.-.E.A....Berthou F. (2002) The DD genotype of the ACE gene polymorphism is associated with diabetic nephropathy in the type-1 diabetics. (PubMed id 11428725) 1 , 4, 9 Azar S.T....Halabi G. (2001) A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. (PubMed id 10969042) 1 , 2 , 9 Donoghue M.... Acton S. (2000) [Angiotensin converting enzyme gene and exercise-induced silent myocardial ischemia in type 2 diabetes mellitus] (PubMed id 15793788) 1 , 4, 9 Xing G....Zhao L. (2005) A study of the relationships between angiotensin- converting enzyme gene, chymase gene polymorphisms, pharmacological treatment with ACE inhibitor and regression of left ventricular hypertrophy in essential hypertension patients treated with benazepril. (PubMed id 15788353) 1 , 4, 9 He H....Hu Y.H. (2005) Effects of perindopril treatment on hemostatic function in patients with essential hypertension in relation to angiotensin converting enzyme (ACE) and plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms. (PubMed id 15673060) 1 , 4, 9 Jastrzebskal M....Wesotowska T. (2004) Multiple Polymorphisms in the renin- angiotensin-aldosterone system (ACE, CYP11B2, AGTR1) and their contribution to hypertension in African Americans and Latinos in the multiethnic cohort. (PubMed id 15545843) 1 , 4, 9 Henderson S.O....Mack W. (2004) ACE2 gene expression is up-regulated in the human failing heart. (PubMed id 15151696) 1 , 2 , 9 Goulter A.B.... Clark K.L. (2004) [ACE and AGTR1 genes polymorphisms in left ventricular hypertrophy pathogenesis in humans] (PubMed id 15612584) 1 , 4, 9 Makeeva O.A....Puzyrev V.P. (2004) ACE gene polymorphism and progression of diabetic nephropathy in Korean type 2 diabetic patients: effect of ACE gene DD on the progression of diabetic nephropathy. (PubMed id 12722028) 1 , 4, 9 Ha S.K....Han D.S. (2003) Angiotensin-converting enzyme genotype, albuminuria and plasma fibrinogen in type 2 diabetes mellitus. (PubMed id 14740347) 1 , 4, 9 Tkac I....Kalina I. (2003) The association study of DRD2, ACE and AGT gene polymorphisms and metamphetamine dependence. (PubMed id 11300226) 1 , 4, 9 Sery O....Zvolsky P. (2001) Association of angiotensinogen M235T and A(-6)G gene polymorphisms with coronary heart disease with independence of essential hypertension: the PROCAGENE study. Prospective Cardiac Gene. (PubMed id 11345362) 1 , 4, 9 Rodriguez-Perez J.C....Ferrario C.M. (2001) A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. (PubMed id 10924499) 1 , 2 , 9 Tipnis S.R....Turner A.J. (2000) Myocardial infarction increases ACE2 expression in rat and humans. (PubMed id 15671045) 1 , 2 , 9 Burrell L.M....Johnston C.I. (2005) [Association of polymorphisms in ACE and CYP11B2 genes with antihypertensive effects of hydrochlorothiazide] (PubMed id 16080804) 1 , 4, 9 Wu S.L....Song S.M. (2005) [Association between angiotensin converting enzyme I/D polymorphism and high-sensitivity C-reactive protein in type 2 diabetic patients with atherosclerosis treated with ramipril] (PubMed id 15958311) 1 , 4, 9 Wang L....Lin S.G. (2005) Associations of baseline blood pressure levels and efficacy of Benazepril treatment with interaction of alpha-adducin and ACE gene polymorphisms in hypertensives. (PubMed id 15773232) 1 , 4, 9 Yu Y....Xu X. (2005) [Apolipoprotein E and angiotensin-converting enzyme gene polymorphisms as risk factors of coronary disease] (PubMed id 15217762) 1 , 4, 9 Bennouar N....Benomar M. (2004) [Association between angiotensin converting enzyme gene, chymase gene and regression of left ventricular hypertrophy in patients treated with angiotensin converting enzyme inhibitors.] (PubMed id 15555355) 1 , 4, 9 He H....Hu Y.H. (2004) Association of angiotensin converting enzyme gene polymorphism with tachycardia cardiomyopathy. (PubMed id 14767579) 1 , 4, 9 Deshmukh P.M....Noti J.D. (2004) [Polymorphic markers of GNB3 (C825T), AGTR1 (A1166C) and ACE (A2350G and I/D) genes in patients with arterial hypertension combined with diabetes mellitus type 2] (PubMed id 15332573) 1 , 4, 9 Karpov R.S....Atroshenkov A.V. (2004) [Association of the complex of polymorphic markers of ACE genes, aldosteron synthetase and endothelial synthetase of nitric oxide with progression of chronic glomerulonephritis] (PubMed id 15532370) 1 , 4, 9 Kamysheva E.S....Shilov E.M. (2004) Association between angiotensin converting enzyme gene polymorphism and coronary artery disease in individuals of the South-Eastern Anatolian population. (PubMed id 15033618) 1 , 4, 9 Nacak M....Aynacioglu S. (2004) DD genotype of ACE gene is a risk factor for intracerebral hemorrhage. (PubMed id 15277638) 1 , 2 , 9 Slowik A.... Szczudlik A. (2004) Angiotensin-converting enzyme and endothelial nitric oxide synthase polymorphisms in patients with atrial fibrillation. (PubMed id 12687832) 1 , 4, 9 Gensini F....Michelucci A. (2003) No association between the angiotensin-converting-enzyme gene insertion/deletion polymorphism and the occurrence of macroangiopathy in patients with diabetes mellitus type 2. (PubMed id 12669270) 1 , 4, 9 Klemm T....Paschke R. (2003) Endothelin-1 and vasopressin plasma levels are not associated with the insertion/deletion polymorphism of the human angiotensin I-converting enzyme gene in patients with coronary artery disease. (PubMed id 12574792) 1 , 4, 9 Al-Fakhri N....Katz N. (2003) Angiotensin-converting enzyme gene polymorphism and coronary heart disease in Turkish type 2 diabetic patients. (PubMed id 12222694) 1 , 4, 9 Araz M....Aktaran S. (2002) High prevalence of polymorphisms of angiotensin-converting enzyme (I/D) and endothelial nitric oxide synthase (Glu298Asp) in patients with systemic sclerosis. (PubMed id 12015245) 1 , 4, 9 Fatini C....Matucci-Cerinic M. (2002) The role of PC-1 and ACE genes in diabetic nephropathy in type 1 diabetic patients: evidence for a polygenic control of kidney disease progression. (PubMed id 12147786) 1 , 4, 9 De Cosmo S....Trischitta V. (2002) [ACE gene I/D-polymorphism and hereditary predisposition to myocardial infarction] (PubMed id 12360613) 1 , 4, 9 Malygina N.A....Serova L.D. (2002) [Association of the renin-angiotensin system gene polymorphism with nephropathy in type II diabetes] (PubMed id 12476891) 1 , 4, 9 Buraczynska M....Ksiazek A. (2002) [Analysis of gene complexes predisposing to coronary atherosclerosis] (PubMed id 11963567) 1 , 4, 9 Spiridonova M.G....Karpov R.S. (2002) Atherosclerosis of carotid arteries and the ace insertion/deletion polymorphism in subjects with diabetes mellitus type 2. (PubMed id 11941276) 1 , 4, 9 Diamantopoulos E.J....Raptis S. (2002) A chymase gene variant is associated with atherosclerosis in venous coronary artery bypass grafts. (PubMed id 11696688) 1 , 4, 9 Ortlepp J.R....Hoffmann R. (2001) [Association between angiotensin system gene polymorphism and essential hypertension] (PubMed id 11484170) 1 , 4, 9 Li X....Han X. (2001) [Association between renin-angiotensin system gene polymorphism and type 2 diabetics with stroke in China] (PubMed id 11774217) 1 , 4, 9 Zhang X....Zhang S. (2001) Albuminuria and the renin-angiotensin system gene polymorphisms in type-2-diabetic and in normoglycemic hypertensive Chinese. (PubMed id 11200871) 1 , 4, 9 Thomas G.N....Chan J.C. (2001) Variation at the Angiotensin-converting enzyme and endothelial nitric oxide synthase genes is associated with the risk of esophageal varices among patients with alcoholic cirrhosis. (PubMed id 11707686) 1 , 4, 9 Coto E....Alvarez V. (2001) Lack of association between angiotensin I-converting enzyme gene deletion polymorphism and cerebrovascular disease in Taiwanese. (PubMed id 11155741) 1 , 4, 9 Lin J.J....Harn H.J. (2000) Relationship between the renin-angiotensin system genes and diabetic nephropathy in the Chinese. (PubMed id 11776100) 1 , 4, 9 Wu S....Li J. (2000) Detection of the association between a deletion polymorphism in the gene encoding angiotensin I-converting enzyme and advanced diabetic retinopathy. (PubMed id 11106834) 1 , 4, 9 Matsumoto A....Makino I. (2000) Angiotensin II type 1 receptor gene A1166C polymorphism is associated with the increased risk of pregnancy-induced hypertension. (PubMed id 11208365) 1 , 4, 9 Nal/ogowska-Gl/osnicka K....Rzempol/uch J. (2000) Angiotensin converting enzyme gene deletion allele is independently and strongly associated with coronary atherosclerosis and myocardial infarction. (PubMed id 8541160) 1 , 4, 9 Arbustini E....Specchia G. (1995) Angiotensin-converting enzyme: zinc- and inhibitor-binding stoichiometries of the somatic and testis isozymes. (PubMed id 1649623) 1 , 2 , 9 Ehlers M.R.W. and Riordan J.F. (1991) [Plasminogen activator inhibitor-1 (PAI-1) 4G/5G and angiotensin converting enzyme (ACE) I/D gene polymorphisms and fibrinolytic activity in patients with essential hypertension and dyslipidemia] (PubMed id 16130596) 1 , 4, 9 Jastrzebska M....Naruszewicz M. (2005) [Pharmacogenetics of angiotensin system in non diabetic nephropathy] (PubMed id 16231503) 1 , 4, 9 Coto E....Campistol J.M. (2005) Angiotensin-converting enzyme and endothelial constitutive nitric oxide synthase polymorphisms in Turkish renal transplant population and possible influence on renal artery atherosclerosis and graft survival. (PubMed id 16213264) 1 , 4, 9 Ozdemir F.N....Haberal M. (2005) [Angiotensin converting enzyme, NO-synthase, and endothelin-1 genes and left ventricular hypertrophy in natives of Yakutia with hypertensive disease] (PubMed id 15699938) 1 , 4, 9 Minushkina L.O....Sidorenko B.A. (2005) [The role of polymorphic markers of vasoactive hormones genes in clinical characteristics of chronic glomerulonephritis] (PubMed id 16078594) 1 , 4, 9 Kamyshova E.S....Shvetsov M.I.u. (2005) Renovascular disease: effect of ACE gene deletion polymorphism and endovascular revascularization. (PubMed id 14718831) 1 , 4, 9 Pizzolo F....Olivieri O. (2004) Angiotensin-converting enzyme gene polymorphism significantly affects renal posttransplantation erythrocytosis. (PubMed id 15013333) 1 , 4, 9 Micozkadioglu H....Haberal M. (2004) Angiotensin-converting enzyme and angiotensin type 2 receptor gene genotype distributions in Italian children with congenital uropathies. (PubMed id 15470205) 1 , 4, 9 Rigoli L....Salpietro C.D. (2004) ACE I allele and eNOS G allele crosstalk may have a role in chronic obstructive pulmonary disease. (PubMed id 15498534) 1 , 4, 9 Ahsan A....Pasha M.A. (2004) Genetic influences on blood pressure within the Stanislas Cohort. (PubMed id 15076187) 1 , 4, 9 Sass C....Visvikis S. (2004) Genetic polymorphism of the renin-angiotensin system on the development of primary vesicoureteral reflux. (PubMed id 14764974) 1 , 4, 9 Yim H.E....Kim S.K. (2004) Angiotensin-converting enzyme (insertion/deletion) and endothelial nitric oxide synthase polymorphisms in patients with systemic lupus erythematosus. (PubMed id 15338496) 1 , 4, 9 Douglas G....Gilkeson G. (2004) Association of peripheral and central arterial wave reflections with the CYP11B2 -344C allele and sodium excretion. (PubMed id 15614025) 1 , 4, 9 Wojciechowska W....Kawecka-Jaszcz K. (2004) [Angiotensin-converting enzyme gene and the brachial artery endothelial dysfunction in type 2 diabetes without angiopathy] (PubMed id 15300633) 1 , 4, 9 Xiang G.D....Wu Y.H. (2004) [Effect of ACE gene polymorphism on carbohydrate metabolism, on oxidative stress and on end-organ damage in type-2 diabetes mellitus] (PubMed id 15156690) 1 , 4, 9 Molnar G.A....Wittmann I. (2004) [Angiotensin-converting enzyme gene polymorphism in patients with obstructive sleep apnea] (PubMed id 15526842) 1 , 4, 9 Rubinsztajn R....Chazan R. (2004) [ACE gene polymorphisms associated with serum ACE activity in the Henan Hans of China] (PubMed id 15651670) 1 , 4, 9 Kong X.D. and Zhang S.Z. (2004) [Association of polymorphisms in the angiotensin system genes with obstructive sleep apnea-hypopnea syndrome] (PubMed id 15387996) 1 , 4, 9 Zhang L.Q....Lin Y.P. (2004) Insertion/deletion plasminogen activator inhibitor 1 and insertion/deletion angiotensin-converting enzyme gene polymorphisms in diabetic retinopathy in type 2 diabetes. (PubMed id 12660488) 1 , 4, 9 Globocnik-Petrovic M....Petrovic D. (2003) Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen. (PubMed id 12871600) 1 , 4, 9 Adams G.T....Kutlar A. (2003) [Effect of ACE gene polymorphism on left ventricular function in patients with type 2 diabetes] (PubMed id 12728591) 1 , 4, 9 Valocik G....Kovacs L. (2003) Crystal structure of the human angiotensin-converting enzyme- lisinopril complex. (PubMed id 12540854) 1 , 2 , 9 Natesh R.... Acharya K.R. (2003) Influence of ACE (I/D) and G460W polymorphism of alpha-adducin in autosomal dominant polycystic kidney disease. (PubMed id 13679477) 1 , 4, 9 Persu A....Devuyst O. (2003) [Association of the G7831A polymorphism of the ACE gene with myocardial ischemia in the Moscow population] (PubMed id 12624945) 1 , 4, 9 Nikitin A.G....Nosikov V.V. (2003) Interaction between ACE and ADD1 gene polymorphisms in the progression of IgA nephropathy in Japanese patients. (PubMed id 12885793) 1 , 4, 9 Narita I....Gejyo F. (2003) The ACE/DD genotype is associated with the extent of exercise-induced left ventricular growth in endurance athletes. (PubMed id 12906984) 1 , 4, 9 Hernandez D....Gonzalez A. (2003) [Arterial hypertension in glomerulonephritis] (PubMed id 14974362) 1 , 4, 9 Oko A....Czekalski S. (2003) ACE gene I/D and NOS3 G894T polymorphisms and response to sildenafil in men with erectile dysfunction. (PubMed id 12837457) 1 , 4, 9 Eisenhardt A....Siffert W. (2003) Study of the polymorphism of angiotensinogen, anigiotensin-converting enzyme and angiotensin receptor in type II diabetes with end-stage renal disease in Taiwan. (PubMed id 12728975) 1 , 4, 9 Chang H.R....Wu M.Y. (2003) ACE and alpha-adducin polymorphism as markers of individual response to diuretic therapy. (PubMed id 12623934) 1 , 4, 9 Sciarrone M.T....Cusi D. (2003) Influence of the alpha-adducin and ACE gene polymorphism on the progression of autosomal-dominant polycystic kidney disease. (PubMed id 12697976) 1 , 4, 9 Merta M....Kmentova D. (2003) [Polymorphism of the promotor region of the angiotensinogen gene and the gene for angiotensin I-converting enzyme in arterial hypertension and myocardial ischemia of the Kazakh ethnic groups] (PubMed id 12669427) 1 , 4, 9 Aitkhozhina N.A. and Liudvikova E.K. (2003) Angiotensin-converting enzyme insertion/deletion polymorphism and polyneuropathy in type 2 diabetes without macroalbuminuria. (PubMed id 12449516) 1 , 4, 9 Ito H....Kurabayashi M. (2002) Angiotensin converting enzyme gene polymorphism and glomerular filtration rate changes in type 2 diabetic patients. (PubMed id 12166538) 1 , 4, 9 Araz M....Aynacioglu S. (2002) Angiotensin converting enzyme insertion/deletion genotype is associated with leukoaraiosis in lacunar syndromes. (PubMed id 11861692) 1 , 4, 9 Hassan A....Bamford J.M. (2002) Lack of association between angiotensin-converting enzyme gene polymorphism and peripheral vascular disease in type 2 diabetic patients in Taiwan. (PubMed id 12419932) 1 , 4, 9 Tseng C.H. and Tseng C.P. (2002) Relationship between polymorphisms in the renin-angiotensin system and nephropathy in type 2 diabetic patients. (PubMed id 11938025) 1 , 4, 9 Fradin S....Reznik Y. (2002) No association between high-altitude tolerance and the ACE I/D gene polymorphism. (PubMed id 12471298) 1 , 4, 9 Dehnert C....Bartsch P. (2002) Renin-angiotensin-aldosterone system (RAAS) gene polymorphism as a risk factor of coronary in-stent restenosis. (PubMed id 12205735) 1 , 4, 9 Ryu S.K....Cho S.Y. (2002) Angiotensin-converting enzyme gene polymorphism is associated with vulnerability to alcoholic cardiomyopathy. (PubMed id 12204015) 1 , 4, 9 Fernandez-Sola J....Urbano-Marquez A. (2002) Exercise-induced changes in insulin action are associated with ACE gene polymorphisms in older adults. (PubMed id 12388790) 1 , 4, 9 Dengel D.R....Supiano M.A. (2002) The estimation of gametic disequilibrium between DNA markers in candidate genes for coronary artery disease (CAD) and the associations of gene complexes with risk factors for CAD. (PubMed id 11507973) 1 , 4, 9 Spiridonova M.G....Karpov R.S. (2001) The insertion/deletion polymorphism of the ACE gene is related to insulin sensitivity in overweight women. (PubMed id 11522714) 1 , 4, 9 Ryan A.S....Ferrell R.E. (2001) [A study of relationship between oral contraceptives and gene polymorphism and types of stroke] (PubMed id 11718065) 1 , 4, 9 Chen J....Zhou J. (2001) The platelet Pl(A2) and angiotensin-converting enzyme (ACE) D allele polymorphisms and the risk of recurrent events after acute myocardial infarction. (PubMed id 11545752) 1 , 4, 9 Bray P.F....Braunwald E. (2001) [Association between insertion-deletion polymorphism of the angiotensin-converting enzyme gene and development of angiopathies in patients with non-insulin dependent diabetes mellitus from the Chuvash Republic] (PubMed id 11234416) 1 , 4, 9 Miloserdova O.V....Limborskaia S.A. (2001) Association of angiotensin converting enzyme and plasminogen activator inhibitor-1 promoter gene polymorphisms with features of the insulin resistance syndrome in patients with premature coronary heart disease. (PubMed id 11427204) 1 , 4, 9 Viitanen L....Laakso M. (2001) Candidate gene polymorphisms in cardiovascular disease: a comparative study of frequencies between a French and an Italian population. (PubMed id 11341749) 1 , 4, 9 Pallaud C....Visvikis S. (2001) Genetic influences on lipid metabolism trait variability within the Stanislas Cohort. (PubMed id 11714857) 1 , 4, 9 Pallaud C....Visvikis S. (2001) Angiotensin-converting enzyme gene polymorphism and microvascular complications in Turkish type 2 diabetic patients. (PubMed id 11640993) 1 , 4, 9 Araz M....Sukru Aynacioglu A. (2001) [ACE gene polymorphism in patients with ischemic brain disease] (PubMed id 12830537) 1 , 4, 9 Skvortsova V.I....Kondrat'eva E.A. (2001) Contribution of gene polymorphisms in the renin-angiotensin system to macroangiopathy in patients with diabetic nephropathy. (PubMed id 11431175) 1 , 4, 9 Wong T.Y....Li P.K. (2001) Relations between ACE gene and ecNOS gene polymorphisms and resistive index in type 2 diabetic patients with nephropathy. (PubMed id 11522715) 1 , 4, 9 Taniwaki H....Nishizawa Y. (2001) Angiotensin-converting enzyme gene polymorphism in patients with systemic lupus. (PubMed id 11505631) 1 , 4, 9 Prkacin I....Mrzljak A. (2001) Angiotensin gene polymorphism as a determinant of posttransplantation renal dysfunction and hypertension. (PubMed id 11544438) 1 , 4, 9 Abdi R....Milford E.L. (2001) Renal outcome and vascular morbidity in systemic lupus erythematosus (SLE): lack of association with the angiotensin-converting enzyme gene polymorphism. (PubMed id 11071585) 1 , 4, 9 Molad Y....Shohat M. (2000) alpha-adducin and angiotensin I-converting enzyme polymorphisms in essential hypertension. (PubMed id 11116113) 1 , 4, 9 Clark C.J....Connell J.M. (2000) ACE/DD genotype is associated with hemostasis balance disturbances reflecting hypercoagulability and endothelial dysfunction in patients with untreated hypertension. (PubMed id 11054622) 1 , 4, 9 Makris T.K....Kyriakidis M.K. (2000) Genetic and environmental factors associated with the development of hypertension in pregnancy. (PubMed id 16369102) 1 , 4 Kobashi G. (2006) Crystal structure of the N domain of human somatic angiotensin I- converting enzyme provides a structural basis for domain-specific inhibitor design. (PubMed id 16476442) 1 , 2 Corradi H.R....Acharya K.R. (2006) Association of APOE (Hha1) and ACE (I/D) gene polymorphisms with type 2 diabetes mellitus in North West India. (PubMed id 16621107) 1 , 4 Singh P.P....Mastana S. (2006) Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6. (PubMed id 16384981) 1 , 4 Haines J.L....Pericak-Vance M.A. (2006) Interactions between five candidate genes and antihypertensive drug therapy on blood pressure. (PubMed id 16314886) 1 , 4 Schelleman H....Klungel O.H. (2006) Analysis of prothrombotic mutations and polymorphisms in children who developed thrombosis in the perioperative period of congenital cardiac surgery. (PubMed id 15831156) 1 , 4 Ozbek N....Tokel N.K. (2005) Genetic factors contribute to bleeding after cardiac surgery. (PubMed id 15892865) 1 , 4 Welsby I.J....Stafford-Smith M. (2005) Association between the eNOS (Glu298Asp) and the RAS genes polymorphisms and premature coronary artery disease in a Turkish population. (PubMed id 15563875) 1 , 4 Berdeli A....Akin M. (2005) Is there an association between ACE and CKMM polymorphisms and cycling performance status during 3-week races? (PubMed id 16037885) 1 , 4 Lucia A....Earnest C.P. (2005) Gene-specific modifying effects of pro-LVH polymorphisms involving the renin-angiotensin-aldosterone system among 389 unrelated patients with hypertrophic cardiomyopathy. (PubMed id 16087648) 1 , 4 Perkins M.J....Ackerman M.J. (2005) Associations of the angiotensin II type 1 receptor A1166C and the endothelial NO synthase G894T gene polymorphisms with silent subcortical white matter lesions in essential hypertension. (PubMed id 16109907) 1 , 4 Henskens L.H....de Leeuw P.W. (2005) Implication of genetic variations in congenital obstructive nephropathy. (PubMed id 16133060) 1 , 4 Hahn H....Cheong H.I. (2005) Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952) 1 , 2 Liu T.... Smith R.D. (2005) Relationship of eNOS gene variants to diseases that have in common an endothelial cell dysfunction. (PubMed id 15784171) 1 , 4 Heltianu C....Simionescu M. (2005) Endothelial nitric oxide synthase gene interactions and the risk of ischaemic stroke. (PubMed id 15595935) 1 , 4 Szolnoki Z....Melegh B. (2005) Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis. (PubMed id 16116425) 1 , 2 Gribouval O.... Gubler M.-C. (2005) Genetic polymorphisms of the renin-angiotensin-aldosterone system and renal insufficiency in essential hypertension. (PubMed id 15662219) 1 , 4 Fabris B....Carretta R. (2005) Association of an orexin 1 receptor 408Val variant with polydipsia-hyponatremia in schizophrenic subjects. (PubMed id 15978554) 1 , 4 Meerabux J....Yoshikawa T. (2005) Genetic polymorphisms in the angiotensin II receptor gene and their association with open-angle glaucoma in a Japanese population. (PubMed id 15914614) 1 , 4 Hashizume K....Miyaki K. (2005) Prevalence of genetic risk factors for coronary artery disease in Corsica island (France). (PubMed id 16248996) 1 , 4 Falchi A....Varesi L. (2005) Close relationship of plasminogen activator inhibitor-1 4G/5G polymorphism and progression of IgA nephropathy. (PubMed id 15481848) 1 , 4 Suzuki H....Watanabe T. (2004) Association of the angiotensin-converting enzyme gene polymorphism with chronic heart failure in Chinese Han patients. (PubMed id 15012915) 1 , 4 Huang W....Sun M. (2004) Genotype announcement in a genetic polymorphism study for health checkup examinees at Nagoya University Hospital. (PubMed id 15279067) 1 , 4 Nishio K....Hamajima N. (2004) Endothelial dysfunction in patients with asthma: the role of polymorphisms of ACE and endothelial NOS genes. (PubMed id 15115168) 1 , 4 Yildiz P....Yilmaz V. (2004) The thiazide-sensitive Na(+)-Cl(-) cotransporter gene, C1784T, and adrenergic receptor-beta3 gene, T727C, may be gene polymorphisms susceptible to the antihypertensive effect of thiazide diuretics. (PubMed id 15824464) 1 , 4 Matayoshi T....Kawano Y. (2004) Interaction between gene polymorphisms of nitric oxide synthase and renin-angiotensin system in the progression of membranous glomerulonephritis. (PubMed id 14767013) 1 , 4 Stratta P....Matullo G. (2004) Angiotensin converting enzyme gene polymorphism in Asian Indian children with congenital uropathies. (PubMed id 14713838) 1 , 4 Bajpai M....Tyagi J. (2004) An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation. (PubMed id 15119966) 1 , 4 Coffey C.S....Moore J.H. (2004) [Angiotensin converting enzyme gene polymorphisms and coronary risk in a Portuguese population] (PubMed id 15732660) 1 , 4 Mendonca I....dos Reis R.P. (2004) Angiotensin-converting enzyme and alpha-2-macroglobulin gene polymorphisms are not associated with Alzheimer's disease in Colombian patients. (PubMed id 14759632) 1 , 4 Camelo D....Arboleda H. (2004) Does angiotensin-converting enzyme gene polymorphism affect blood pressure? Findings after 6 years of follow-up in healthy subjects. (PubMed id 15012913) 1 , 4 Di Pasquale P....Paterna S. (2004) Genetic risk of atherosclerotic renal artery disease: the candidate gene approach in a renal angiography cohort. (PubMed id 15326089) 1 , 4 van Onna M....de Leeuw P.W. (2004) Population genetics of apolipoproteins A-IV, E, and H, and the angiotensin converting enzyme (ACE): associations with lipids, and apolipoprotein levels in American Samoans. (PubMed id 15252864) 1 , 4 Crews D.E....Kamboh M.I. (2004) Association of maternal histocompatibility at class II HLA loci with maternal microchimerism in the fetus. (PubMed id 15128924) 1 , 4 Berry S.M....Kaplan J. (2004) Exploration of myostatin polymorphisms and the angiotensin-converting enzyme insertion/deletion genotype in responses of human muscle to strength training. (PubMed id 15083369) 1 , 4 Thomis M.A....Beunen G.P. (2004) Association between polymorphisms of the angiotensin-converting enzyme and angiotensinogen genes and allergic rhinitis in a Korean population. (PubMed id 15112973) 1 , 4 Kim J.J....Lee J.H. (2004) [Gene polymorphisms of rennin-angiotensin system and coronary artery thrombosis disease.] (PubMed id 15498133) 1 , 4 Zhu T.N....Shen T. (2004) Sex difference in the effect of ACE-DD genotype on the risk of premature myocardial infarction. (PubMed id 15026870) 1 , 4 Petrovic D....Peterlin B. (2004) [Impact of angiotensin-converting enzyme, angiotensinogen, endothelial NO synthase, and bradykinin receptor B2 gene polymorphisms on myocardium in patients with hypertension and in athletes] (PubMed id 15112434) 1 , 4 Shneider O.V....Mikhel'son V.M. (2004) A polymorphism in the angiotensin 1-converting enzyme gene is associated with damage to cerebral cortical white matter in Alzheimer's disease. (PubMed id 14698449) 1 , 4 Tian J....Mann D.M. (2004) APOE promoter, ACE1 and CYP46 polymorphisms and beta-amyloid in Alzheimer's disease. (PubMed id 15106838) 1 , 4 Chalmers K.A....Love S. (2004) Association of variants in angiotensin-converting enzyme and endothelin-1 genes with phototherapy in cutaneous T-cell lymphoma. (PubMed id 15818445) 1 , 4 Vasku V....Vasku A. (2004) Glu298Asp endothelial nitric oxide synthase polymorphism is a risk factor for erectile dysfunction in the Mexican Mestizo population. (PubMed id 15292102) 1 , 4 Rosas-Vargas H....Salamanca F. (2004) Bradykinin receptor gene variant and human physical performance. (PubMed id 14607851) 1 , 4 Williams A.G....Montgomery H.E. (2004) The renin-angiotensin system and endothelial nitric oxide synthase gene polymorphisms and cyclosporine toxicity in renal transplant patients. (PubMed id 15013322) 1 , 4 Ozdemir F.N....Haberal M. (2004) Association of the genetic polymorphisms of the renin-angiotensin system and endothelial nitric oxide synthase with chronic renal transplant dysfunction. (PubMed id 15385810) 1 , 4 Akcay A....Haberal M. (2004) Clinical relevance of angiotensin-converting enzyme gene polymorphisms to predict risk of mechanical ventilation after coronary artery bypass graft surgery. (PubMed id 15071379) 1 , 4 Yende S....Wunderink R.G. (2004) [Relations between endothelial nitric oxide synthase and angiotensin-converting gene polymorphisms and certain biochemical parameters in patients with cardiac syndrome X] (PubMed id 15724677) 1 , 4 Kolasinska-Kloch W....Dembinska-Kiec A. (2004) Angiotensin-converting enzyme genotype is a predictive factor in the peak panel-reactive antibody response. (PubMed id 15013293) 1 , 4 Akcay A....Haberal M. (2004) [Angiotensin converting enzyme gene polymorphism and type 2 diabetic retinopathy] (PubMed id 16134592) 1 , 4 Liao L....Han X.Y. (2004) Impaired fibrinolysis in retinal vein occlusion: a role for genetic determinants of PAI-1 levels. (PubMed id 15213845) 1 , 4 Gori A.M....Prisco D. (2004) Lack of association between polymorphisms in angiotensin-converting-enzyme and methylenetetrahydrofolate reductase genes and normal cognitive ageing in humans. (PubMed id 12875914) 1 , 4 Visscher P.M....Deary I.J. (2003) Renin-angiotensin system polymorphisms and renal scarring. (PubMed id 12579398) 1 , 4 Pardo R....Braga S. (2003) Methylenetetrahydrofolate reductase and angiotensin converting enzyme gene polymorphisms in two genetically and diagnostically distinct cohort of Alzheimer patients. (PubMed id 12928053) 1 , 4 Seripa D....Fazio V.M. (2003) Epidemiology of essential hypertension: the role of genetic polymorphism. (PubMed id 12800945) 1 , 4 Romano-Spica V....Savi L. (2003) PAI-1 4G/5G and ACE I/D gene polymorphisms and the occurrence of myocardial infarction in patients on intermittent dialysis. (PubMed id 12748347) 1 , 4 Aucella F....Stallone C. (2003) [A cross-sectional study on angiotensin-converting enzyme and angiotensin II type I receptor gene polymorphism and cerebral infarction] (PubMed id 14521778) 1 , 4 Yuan X.D....Li H.F. (2003) Effects of captopril administration on pulmonary haemodynamics and tissue oxygenation during exercise in ACE gene subtypes in patients with COPD: a preliminary study. (PubMed id 12832683) 1 , 4 Kanazawa H....Yoshikawa J. (2003) Interactive effects of the ACE DD polymorphism with the NOS III homozygous G849T (Glu298-->Asp) variant in determining endothelial function in coronary artery disease. (PubMed id 14989558) 1 , 4 Schmidt M.A....Rajagopalan S. (2003) Genetic polymorphism of the renin-angiotensin-aldosterone system and arterial hypertension in the Italian population: the GENIPER Project. (PubMed id 14508191) 1 , 4 Castellano M....Rossi F. (2003) Genetic polymorphisms in the Renin-Angiotensin system in high-altitude and low-altitude Native American populations. (PubMed id 12556231) 1 , 4 Rupert J.L....Devine D.V. (2003) ACE DD genotype: an independent predisposition factor to venous thromboembolism. (PubMed id 12864773) 1 , 4 Fatini C....Abbate R. (2003) [Insertion-deletion polymorphism of the angiotensin converting enzyme gene and its relationship to serum levels of free amino acids in the patients with connective tissue dysplasias] (PubMed id 14515472) 1 , 4 Kazakov V.I....Tomilin N.V. (2003) [ACE gene polymorphism and renal scarring in children with urinary tract infection and vesicoureteric reflux: preliminary results] (PubMed id 12728665) 1 , 4 Kowalewska-Pietrzak M....Bodalski J. (2003) [Genetic predictors of left ventricular hypertrophy: do polymorphisms of peroxisome proliferator activated nuclear receptor genes play any role?] (PubMed id 14671555) 1 , 4 Minushkina L.O....Sidorenko B.A. (2003) [Characteristics of hemodynamics and metabolism and structural polymorphisms of angiotensin converting enzyme and angiotensin II type I receptors genes in women of childbearing] (PubMed id 12891302) 1 , 4 Boitsov S.A....Linchak R.M. (2003) Relationship between angiotensin-converting enzyme ID polymorphism and VO(2max) of Chinese males. (PubMed id 12967686) 1 , 4 Zhao B....Lee L.K. (2003) Genetic determinants of nonmodulating hypertension. (PubMed id 14530292) 1 , 4 Kosachunhanun N....Williams G.H. (2003) Effect of angiotensin-converting enzyme insertion/deletion polymorphism DD genotype on high-frequency heart rate variability in African Americans. (PubMed id 14675596) 1 , 4 Thayer J.F....Abernethy D.R. (2003) Polymorphisms in the ACE and PAI-1 genes are associated with recurrent spontaneous miscarriages. (PubMed id 14585904) 1 , 4 Buchholz T....Thaler C.J. (2003) A microarray minisequencing system for pharmacogenetic profiling of antihypertensive drug response. (PubMed id 12544508) 1 , 4 Liljedahl U....Syvanen A.C. (2003) Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme. (PubMed id 12542396) 1 , 2 Gordon K.... Sturrock E.D. (2003) Apolipoprotein E, angiotensin-converting enzyme and alpha-1-antichymotrypsin genotypes are not associated with post-stroke dementia. (PubMed id 12736093) 1 , 4 Arpa A....Bornstein B. (2003) Angiotensin-I-converting enzyme insertion/deletion polymorphism and high urinary albumin concentration in French Type 2 diabetes patients. (PubMed id 12873298) 1 , 4 Hadjadj S....Vasmant D. (2003) Variation in the DCP1 gene, encoding the angiotensin converting enzyme ACE, is not associated with increased susceptibility to Alzheimer's disease. (PubMed id 12605101) 1 , 4 Carbonell J....Gurling H. (2003) Potential thrombophilic mutations/polymorphisms in patients with no flow-limiting stenosis after myocardial infarction. (PubMed id 12514663) 1 , 4 French J.K....Cooke G. (2003) Association between angiotensin I-converting enzyme gene insertion/deletion polymorphism and mitral valve prolapse syndrome. (PubMed id 12514670) 1 , 4 Chou H.T....Tsai F.J. (2003) [Angiotensin converting enzyme gene polymorphism and type 2 diabetic nephropathy] (PubMed id 15804059) 1 , 4 Liao L....Chen H.L. (2003) Genetic risk factors for erectile dysfunction and genetic determinants of drug response--on the way to improve drug safety? (PubMed id 12825146) 1 , 4 Eisenhardt A. and Siffert W. (2003) Renin-angiotensin-aldosterone system loci and multilocus interactions in young-onset essential hypertension. (PubMed id 12611423) 1 , 4 Porto P.I....Pirola C.J. (2003) Associations between hypertension and genes in the renin-angiotensin system. (PubMed id 12695419) 1 , 4 Zhu X....Chakravarti A. (2003) Overestimation of genetic risks owing to small sample sizes in cardiovascular studies. (PubMed id 12791034) 1 , 4 Morgan T.M....Krumholz H.M. (2003) Genetic variation in angiotensin I-converting enzyme (ACE) and breast cancer risk: the multiethnic cohort. (PubMed id 14583500) 1 , 4 Haiman C.A....Henderson B.E. (2003) A/C1166 gene polymorphism of the angiotensin II type 1 receptor (AT1) and ambulatory blood pressure: the Ohasama Study. (PubMed id 12627873) 1 , 4 Kikuya M....Matsubara M. (2003) Impact of renin-angiotensin-aldosterone system gene variants on the severity of hypertension in patients with newly diagnosed hypertension. (PubMed id 14643573) 1 , 4 Tiago A.D....Norton G.R. (2003) Angiotensin I-converting enzyme gene polymorphism in two ethnic groups living in Brazil's southern region: association with age. (PubMed id 14528043) 1 , 4 Da Cruz I.B....Moriguchi E.H. (2003) Association between the A1166C polymorphism of the angiotensin II receptor type 1 and progression of chronic renal insufficiency. (PubMed id 12832734) 1 , 4 Coll E....Poch E. (2003) DD ACE gene polymorphism is associated with increased coronary artery endothelial dysfunction: the PREFACE trial. (PubMed id 12695469) 1 , 4 Mulder H.J....Bruschke A.V. (2003) Effect of six candidate genes on early aging in a French population. (PubMed id 12889841) 1 , 4 Xia Y....Visvikis S. (2003) Angiotensin converting enzyme gene insertion/deletion polymorphism: case-control association studies in schizophrenia, major affective disorder, and tardive dyskinesia and a family-based association study in schizophrenia. (PubMed id 11920854) 1 , 4 Segman R.H....Lerer B. (2002) Allele and genotype frequencies of polymorphic DCP1, CETP, ADRB2, and HTR2A in the Egyptian population. (PubMed id 11956670) 1 , 4 Hamdy S.I....Mizugaki M. (2002) Association of polymorphisms of the renin-angiotensin system and bradykinin B2 receptor with ACE-inhibitor-related cough. (PubMed id 12522467) 1 , 4 Mukae S....Katagiri T. (2002) Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme. (PubMed id 12459472) 1 , 2 Harmer D.... Clark K.L. (2002) [Angiotensinogen and angiotensin-I converting enzyme gene variations in Chinese pregnancy induced hypertension] (PubMed id 12575194) 1 , 4 Bai H....Liu B. (2002) An aldosterone synthase gene variant is associated with improvement in left ventricular ejection fraction in dilated cardiomyopathy. (PubMed id 12031704) 1 , 4 Tiago A.D....Norton G.R. (2002) A comparison of combinatorial partitioning and linear regression for the detection of epistatic effects of the ACE I/D and PAI-1 4G/5G polymorphisms on plasma PAI-1 levels. (PubMed id 12123491) 1 , 4 Moore J.H....Vaughan D.E. (2002) Cryptogenic stroke in relation to genetic variation in clotting factors and other genetic polymorphisms among young men and women. (PubMed id 12468767) 1 , 4 Austin H....Hooper W.C. (2002) Recipient RAS gene variants and renal allograft function. (PubMed id 11923700) 1 , 4 Nicod J....Ferrari P. (2002) Association of angiotensin-converting-enzyme gene polymorphism with the depressor response to mild exercise therapy in patients with mild to moderate essential hypertension. (PubMed id 12372063) 1 , 4 Zhang B....Saku K. (2002) Role of the alpha-adducin genotype on renal disease progression. (PubMed id 11918733) 1 , 4 Nicod J....Ferrari P. (2002) [Genetics of blood coagulation in young stroke patients] (PubMed id 12122980) 1 , 4 Pongracz E....Nagy Z. (2002) The angiotensin-converting enzyme DD genotype is associated with glomerulopathy lesions in type 2 diabetes. (PubMed id 11756350) 1 , 4 Solini A....Fioretto P. (2002) Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome. (PubMed id 12204859) 1 , 4 Marshall R.P....Laurent G.J. (2002) Association study of angiotensin I-converting enzyme polymorphism and symptomatology and antidepressant response in major depressive disorders. (PubMed id 12203048) 1 , 4 Hong C.J....Tsai S.J. (2002) Angiotensin-converting enzyme gene polymorphism and its association with essential hypertension in a Tibetan population. (PubMed id 12135330) 1 , 4 Gesang L....Chan Y. (2002) The ACE insertion/deletion polymorphism is not associated with the metabolic syndrome (WHO Definition) in Brazilian type 2 diabetic patients. (PubMed id 12453999) 1 , 4 Costa L.A....Gross J.L. (2002) Association of the D allele of the angiotensin I converting enzyme polymorphism with malignant vascular injury. (PubMed id 11836444) 1 , 4 Mayer N.J....Fleming S. (2002) ACE gene insertion/deletion polymorphism associated with 1998 World Health Organization definition of metabolic syndrome in Chinese type 2 diabetic patients. (PubMed id 12032106) 1 , 4 Lee Y.J. and Tsai J.C. (2002) D(2) dopamine receptor (DRD2) polymorphism is associated with severity of alcohol dependence. (PubMed id 11918988) 1 , 4 Connor J.P....Noble E.P. (2002) Genetic factors associated with the absence of atherosclerosis in octogenarians. (PubMed id 12196500) 1 , 4 Zuliani G....Fellin R. (2002) [The association between angiotensin I converting enzyme gene polymorphism and Chinese late onset Alzheimer disease] (PubMed id 12362316) 1 , 4 Wu C....Qiao Y. (2002) Association between the angiotensin-converting enzyme gene polymorphisms and tissue oxygenation during exercise in patients with COPD. (PubMed id 11888948) 1 , 4 Kanazawa H....Yoshikawa J. (2002) [Clinico-genetic aspects of the hypotensive response and regression of left ventricular hypertrophy in arterial hypertension patients] (PubMed id 12469628) 1 , 4 Moiseev V.S....Timofeeva S.G. (2002) Association between genetic polymorphism of angiotensin-converting enzyme gene and Parkinson's disease. (PubMed id 12084438) 1 , 4 Lin J.J....Lin S.Z. (2002) Insertion/deletion polymorphism of the ACE gene is associated with type 2 diabetes. (PubMed id 12031990) 1 , 4 Feng Y....Xu X. (2002) Lack of association between angiotensin converting enzyme polymorphism and sporadic Alzheimer's disease. (PubMed id 12459519) 1 , 4 Monastero R....Camarda R. (2002) Multi-locus interactions predict risk for post-PTCA restenosis: an approach to the genetic analysis of common complex disease. (PubMed id 12082592) 1 , 4 Zee R.Y....Lindpainter K. (2002) Carotid and femoral intima-media thickness in relation to three candidate genes in a Caucasian population. (PubMed id 12172317) 1 , 4 Balkestein E.J....Staessen J.A. (2002) ACE and PC-1 gene polymorphisms in normoalbuminuric Type 1 diabetic patients: a 10-year prospective study. (PubMed id 12126783) 1 , 4 de Azevedo M.J....Gross J.L. (2002) Relationship among (1)H-magnetic resonance spectroscopy, brain volumetry and genetic polymorphisms in humans with memory impairment. (PubMed id 12113906) 1 , 4 Bartres-Faz D....Moral P. (2002) [The relationship of aldosterone synthase gene polymorphism with hypertension and left ventricular hypertrophy] (PubMed id 12133420) 1 , 4 Chen A....Qian X. (2002) Angiotensin converting enzyme DD genotype is associated with hypertensive crisis. (PubMed id 12394950) 1 , 4 Sunder-Plassmann G....Fodinger M. (2002) Lack of association between polymorphisms in the testis-specific angiotensin converting enzyme gene and male infertility in an Asian population. (PubMed id 11870238) 1 , 4 Liao W.X. and Roy A.C. (2002) Angiotensin-converting enzyme gene and longevity in the Xin Jiang Uighur autonomous region of China: an association study. (PubMed id 11773214) 1 , 4 Rahmutula D....Hen-Chen Z. (2002) Association between angiotensin I-converting enzyme gene polymorphism and hypertension in selected individuals of the Bangladeshi population. (PubMed id 12297007) 1 , 4 Morshed M....Akhteruzzaman S. (2002) Angiotensin I-converting enzyme and chymase gene polymorphisms - relationship to left ventricular mass in type 2 diabetes patients. (PubMed id 12165749) 1 , 4 Gumprecht J....Czank P. (2002) Polymorphisms in the angiotensinogen and angiotensin II type 1 receptor gene are related to change in left ventricular mass during antihypertensive treatment: results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA) trial. (PubMed id 11910301) 1 , 4 Kurland L....Lind L. (2002) Angiotensin-converting enzyme gene polymorphism and vascular manifestations in Korean patients with SLE. (PubMed id 12043886) 1 , 4 Uhm W.S....Yoo D.H. (2002) [A study of insertion/delation polymorphism of the angiotensin-converting enzyme gene in pilots] (PubMed id 15901553) 1 , 4 Cai Q....Jiang J.D. (2002) Characterization of high-altitude pulmonary hypertension in the Kyrgyz: association with angiotensin-converting enzyme genotype. (PubMed id 12406857) 1 , 4 Aldashev A.A....Morrell N.W. (2002) Study of the association between Alzheimer's disease and angiotensin-converting enzyme gene polymorphism using DNA from lymphocytes. (PubMed id 11803189) 1 , 4 Cheng C.Y....Tsai S.J. (2002) Pulmonary hypertension in type 1 Gaucher's disease: genetic and epigenetic determinants of phenotype and response to therapy. (PubMed id 12359135) 1 , 4 Mistry P.K....Goldman M.E. (2002) [Genetic polymorphisms of the renin-angiotensin system and essential hypertension] (PubMed id 12015946) 1 , 4 Poch E....Divison J.A. (2002) Haptoglobin phenotype and the risk of restenosis after coronary artery stent implantation. (PubMed id 11909563) 1 , 4 Roguin A....Levy A.P. (2002) Renal function in relation to three candidate genes. (PubMed id 11728946) 1 , 4 Wang J.G....Bianchi G. (2001) Insertion-deletion polymorphism in the gene for angiotensin-converting enzyme is associated with obstetric cholestasis but not with preeclampsia. (PubMed id 11568784) 1 , 4 Heiskanen J.T....Heinonen S.T. (2001) [Polymorphism of angiotensin converting enzyme (ACE) and TNF-beta genes in men with disorders of spermatogenesis--pilot study] (PubMed id 11732226) 1 , 4 Kucera M....Znojil V. (2001) Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia. (PubMed id 11328206) 1 , 4 Zuliani G....Fellin R. (2001) Genetic polymorphisms of the renin-angiotensin-aldosterone system in end-stage renal disease. (PubMed id 11422735) 1 , 4 Lovati E....Ferrari P. (2001) Molecular basis of salt sensitivity in human hypertension. Evaluation of renin-angiotensin-aldosterone system gene polymorphisms. (PubMed id 11711524) 1 , 4 Poch E....de La Sierra A. (2001) Association study of angiotensin-converting enzyme gene polymorphism with schizophrenia and polydipsia. (PubMed id 11408790) 1 , 4 Ouyang W.C....Tsai S.J. (2001) Testing genetic susceptibility loci for alcoholic heart muscle disease. (PubMed id 11696658) 1 , 4 Kajander O.A....Karhunen P.J. (2001) [Renin-angiotensin system genetic polymorphisms and essential hypertension in the Spanish population] (PubMed id 11707217) 1 , 4 Giner V....Redon J. (2001) Failure of aldosterone suppression despite angiotensin-converting enzyme (ACE) inhibitor administration in chronic heart failure is associated with ACE DD genotype. (PubMed id 11401115) 1 , 4 Cicoira M....Zardini P. (2001) Angiotensin II type 1 receptor-153A/G and 1166A/C gene polymorphisms and increase in aortic stiffness with age in hypertensive subjects. (PubMed id 11288810) 1 , 4 Lajemi M....Benetos A. (2001) Linkage analysis of angiotensin-converting enzyme (ACE) insertion/deletion polymorphism and systemic lupus erythematosus. (PubMed id 11377823) 1 , 4 Kaufman K.M....Harley J.B. (2001) Lack of association of the renin-angiotensin system genes polymorphisms and left ventricular hypertrophy in hypertension. (PubMed id 11688760) 1 , 4 Shlyakhto E.V....Conrady A.O. (2001) Duration of non-Insulin-dependent diabetes mellitus and the TNF-beta NcoI genotype as predictive factors in proliferative diabetic retinopathy. (PubMed id 11399938) 1 , 4 Kankova K....Vacha J. (2001) Linkage and association analysis of angiotensin I-converting enzyme (ACE)-gene polymorphisms with ACE concentration and blood pressure. (PubMed id 11283791) 1 , 4 Zhu X....Ward R. (2001) Angiotensin-converting enzyme gene insertion/deletion, not bradykinin B2 receptor -58T/C gene polymorphism, associated with angiotensin-converting enzyme inhibitor-related cough in Chinese female patients with non-insulin-dependent diabetes mellitus. (PubMed id 11699055) 1 , 4 Lee Y.J. and Tsai J.C. (2001) Carotid and femoral artery stiffness in relation to three candidate genes in a white population. (PubMed id 11711521) 1 , 4 Balkestein E.J....Struijker-Boudier H.A. (2001) [Meta-analysis on the association of ACE/ID polymorphism and essential hypertension in Chinese population] (PubMed id 11840772) 1 , 4 Qu H....Lin S. (2001) Interactions of lymphotoxin alpha (TNF-beta), angiotensin-converting enzyme (ACE), and endothelin-1 (ET-1) gene polymorphisms in adult periodontitis. (PubMed id 11210078) 1 , 4 Holla L.I....Vacha J. (2001) ACE gene polymorphism as a prognostic indicator in patients with type 2 diabetes and established renal disease. (PubMed id 11723093) 1 , 4 Fava S....Hattersley A.T. (2001) Association between the NOS3 (-786 T/C) and the ACE (I/D) DNA genotypes and early coronary artery disease. (PubMed id 11485372) 1 , 4 Alvarez R....Coto E. (2001) Renin-angiotensin system gene polymorphisms, blood pressure, dyslipidemia, and diabetes in Hong Kong Chinese: a significant association of tne ACE insertion/deletion polymorphism with type 2 diabetes. (PubMed id 11213892) 1 , 4 Thomas G.N....Critchley J.A. (2001) Effects of three candidate genes on prevalence and incidence of hypertension in a Caucasian population. (PubMed id 11518842) 1 , 4 Staessen J.A....Bianchi G. (2001) Increased shedding of angiotensin-converting enzyme by a mutation identified in the stalk region. (PubMed id 11076943) 1 , 2 Eyries M.... Soubrier F. (2001) Angiotensin converting enzyme genetic polymorphism is not associated with hypertension in a cross-sectional sample of a Japanese population: the Shibata Study. (PubMed id 11204304) 1 , 4 Zaman M.M....Tanaka H. (2001) [Renin-angiotensin system genes in chronic glomerulonephritis] (PubMed id 11865575) 1 , 4 Buraczynska M....Ksiazek A. (2001) An association study of five genetic loci and left ventricular hypertrophy amongst Gulf Arabs. (PubMed id 11768721) 1 , 4 Obineche E.N....Bokhari A.M. (2001) Elite swimmers and the D allele of the ACE I/D polymorphism. (PubMed id 11354635) 1 , 4 Woods D....Montgomery H. (2001) Age-dependent prevalence of vascular disease-associated polymorphisms among 2689 volunteer blood donors. (PubMed id 11568114) 1 , 4 Hessner M.J....Raife T.J. (2001) Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease. (PubMed id 11436125) 1 , 4 Prince J.A....Brookes A.J. (2001) Abdominal aortic aneurysm in normotensive patients: association with angiotensin-converting enzyme gene polymorphism. (PubMed id 11352521) 1 , 4 Pola R....Pola P. (2001) Increased common carotid intima-media thickness in UK African Caribbeans and its relation to chronic inflammation and vascular candidate gene polymorphisms. (PubMed id 11692002) 1 , 4 Markus H....Cullinane M. (2001) Association study of eight candidate genes with renin status in mild-to-moderate hypertension in patients of African ancestry. (PubMed id 11447495) 1 , 4 Tiago A.D....Norton G.R. (2001) Angiotensin-converting enzyme inhibition is associated with reduced troponin release in non-ST-elevation acute coronary syndromes. (PubMed id 11527624) 1 , 4 Kennon S....Timmis A.D. (2001) Synergistic effect between apolipoprotein E and angiotensinogen gene polymorphisms in the risk for early myocardial infarction. (PubMed id 11106322) 1 , 4 Batalla A....Coto E. (2000) Angiotensin converting enzyme DD genotype affects the changes of plasma plasminogen activator inhibitor-1 activity after primary percutaneous transluminal coronary angioplasty in acute myocardial infarction patients. (PubMed id 11289708) 1 , 4 Prisco D....Gensini G.F. (2000) Angiotensinogen and angiotensin converting enzyme gene polymorphisms and the risk of bipolar affective disorder in humans. (PubMed id 11027844) 1 , 4 Meira-Lima I.V....Vallada H. (2000) Gene polymorphisms of endothelial nitric oxide synthase and angiotensin-converting enzyme in patients with asthma. (PubMed id 11030378) 1 , 4 Lee Y.C....Kim D.S. (2000) Association between angiotensin-converting enzyme gene and late onset Alzheimer's disease in Han chinese. (PubMed id 11078932) 1 , 4 Yang J.D....He L. (2000) ACE-gene polymorphism is associated with the development of allograft vascular disease in heart transplant recipients. (PubMed id 11124487) 1 , 4 Pethig K....Haverich A. (2000) Gene polymorphisms of endothelial nitric oxide synthase and angiotensin-converting enzyme in patients with lung cancer. (PubMed id 11361058) 1 , 4 Cheon K.T....Lee Y.C. (2000) A DNA polymorphism at the alpha2-macroglobulin gene is associated with the severity of rheumatoid arthritis. (PubMed id 11036822) 1 , 4 Zapico I....Alvarez V. (2000) Is there an association between angiotensin-converting enzyme gene variants and chronic nonproductive cough? (PubMed id 11035682) 1 , 4 McGarvey L.P....Maxwell A.P. (2000) No association of an insertion/deletion polymorphism in the angiotensin I converting enzyme gene with bipolar or unipolar affective disorders. (PubMed id 11121171) 1 , 4 Furlong R.A....Rubinsztein D.C. (2000) Deletion polymorphisms in the angiotensin converting enzyme gene are associated with pulmonary hypertension evoked by exercise challenge in patients with chronic obstructive pulmonary disease. (PubMed id 11029323) 1 , 4 Kanazawa H....Yoshikawa J. (2000) Polymorphism of angiotensin converting enzyme, angiotensinogen, and angiotensin II type 1 receptor genes and end-stage renal failure in IgA nephropathy: IGARAS--a study of 274 Men. (PubMed id 11053482) 1 , 4 Frimat L....Kessler M. (2000) The DD genotype of the ACE gene polymorphism is associated with progression of diabetic nephropathy to end stage renal failure in IDDM. (PubMed id 10099885) 2 , 4 Vleming L.J.... van Kooten C. (1999) Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis. (PubMed id 10391210) 1 , 2 Halushka M.K.... Chakravarti A. (1999) Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. (PubMed id 9916793) 1 , 4 Kehoe P.G....Owen M.J. (1999) Identification of N-linked glycosylation sites in human testis angiotensin-converting enzyme and expression of an active deglycosylated form. (PubMed id 9013598) 1 , 2 Yu X.C....Riordan J.F. (1997) Assignment of free and disulfide-bonded cysteine residues in testis angiotensin-converting enzyme: functional implications. (PubMed id 8755737) 1 , 2 Sturrock E.D.... Riordan J.F. (1996) The testicular transcript of the angiotensin I-converting enzyme encodes for the ancestral, non-duplicated form of the enzyme. (PubMed id 2547653) 1 , 2 Lattion A.L....Alhenc-Gelas F. (1989) Purification of human lung angiotensin-converting enzyme by high- performance liquid chromatography: properties and N-terminal amino acid sequence. (PubMed id 2558109) 1 , 2 Takeuchi K....Yotsumoto H. (1989) Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning. (PubMed id 2849100) 1 , 2 Soubrier F.... Corbol P. (1988) Discrepancy between intrarenal messenger RNA and prot ein expression of ACE and ACE2 in human diabetic nephropathy. (PubMed id 19077419) 1 , 9 Wang G....Szeto C.C. (2009) A genome-wide search replicates evidence of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE) unlinked to the ACE gene. (PubMed id 18544166) 1 , 9 McKenzie C.A....Cooper R.S. (2008) Regulation of ACE gene expression and plasma levels during rat postnatal development. (PubMed id 7977726) 1 , 9 Costerousse O....Alhenc-Gelas F. (1994) Reduction of pneumonia risk by an angiotensin I-converting enzyme inhibitor in elderly Japanese inpatients according to insertion/deletion polymorphism of the angiotensin I-converting enzyme gene. (PubMed id 16202861) 1 , 9 Takahashi T....Matsumoto M. (2005) The influence of mode of delivery and ACE genotype on serum angiotensin converting enzyme (ACE) activity in the mother and infant at term. (PubMed id 17123697) 1 , 9 Uma R....Murphy D.J. (2007) Angiotensin-1-converting enzyme (ACE) gene polymorphism, plasma ACE levels, and their association with the metabolic syndrome and electrocardiographic coronary artery disease in Pima Indians. (PubMed id 9591757) 4, 9 Nagi D.K....Knowler W.C. (1998) Angiotensin I-converting enzyme (ACE) inhibitors and restenosis after coronary artery stenting in patients with the DD genotype of the ACE gene. (PubMed id 12798565) 1 , 9 Koch W....Kastrati A. (2003) [Association of angiotensin I-converting enzyme gene polymorphism with ACE and PAI-1 levels in Guangdong Chinese Han patients with essential hypertension] (PubMed id 18024289) 1 , 9 Zhang Y.L....Zhang J.M. (2007) Amyloid beta-protein is degraded by cellular angiotensin-converting enzyme (ACE) and elevated by an ACE inhibitor. (PubMed id 16154999) 1 , 9 Hemming M.L. and Selkoe D.J. (2005) Serum angiotensin I-converting enzyme is reduced in Crohn's disease and ulcerative colitis irrespective of genotype. (PubMed id 11569699) 1 , 9 Matsuda T....Kawakami Y. (2001) The serum angiotensin-converting enzyme and angiotensin II response to altered posture and acute exercise, and the influence of ACE genotype. (PubMed id 14595564) 1 , 9 Woods D....Montgomery H. (2004) [No relation between angiotensin-converting enzyme (ACE) inhibitor-induced cough and ACE gene polymorphism, plasma bradykinin, substance P and ACE inhibitor concentration in Japanese patients] (PubMed id 11265121) 1 , 9 Okumura H....Rikihisa T. (2001) Angiotensin I-converting enzyme mutation (Trp1197Stop ) causes a dramatic increase in blood ACE. (PubMed id 20011602) 1 , 9 Nesterovitch A.B....Danilov S.M. (2009) [Relationship of the disease severity with ACE gene polymorphism and serum ACE activity in preterm infants] (PubMed id 19102831) 1 , 9 Han T.Y....Ye H.M. (2008) Signaling via the angiotensin-converting enzyme results in the phosphorylation of the nonmuscle myosin heavy chain IIA. (PubMed id 16186248) 1 , 9 Kohlstedt K....Fleming I. (2006) Human ACE and bradykinin B2 receptors form a complex at the plasma membrane. (PubMed id 17077303) 1 , 9 Chen Z....Tan F. (2006) Replacement of the transmembrane anchor in angiotensin I-converting enzyme (ACE) with a glycosylphosphatidylinositol tail affects activation of the B2 bradykinin receptor by ACE inhibitors. (PubMed id 10748135) 1 , 9 Marcic B....Tan F. (2000) Overview of the angiotensin-converting-enzyme inhibitors. (PubMed id 11030016) 7, 9 Piepho R.W. (2000) Association of angiotensin I-converting enzyme gene polymorphism with susceptibility to antiproteinuric effect of angiotensin I-converting enzyme inhibitors in patients with proteinuria. (PubMed id 8749698) 4, 9 Moriyama T....Imai E. (1995) Angiotensin-converting enzyme levels and activity in Alzheimer's disease: differences in brain and CSF ACE and association with ACE1 genotypes. (PubMed id 19956428) 1 , 9 Miners S....Kehoe P.G. (2009) The impact of ACE genotype on serum ACE activity in a black South African male population. (PubMed id 17227472) 1 , 9 Payne J.R....Montgomery H.E. (2007) Increased expression of monocytic angiotensin-converting enzyme in dialysis patients with cardiovascular disease. (PubMed id 16476718) 1 , 9 Ulrich C....Girndt M. (2006) Angiotensin I-converting enzyme and metabolism of the haematological peptide N-acetyl-seryl-aspartyl-lysyl-proline. (PubMed id 11903317) 1 , 9 Azizi M....Menard J. (2001) Point mutation in the stalk of angiotensin-converting enzyme causes a dramatic increase in serum angiotensin-converting enzyme but no cardiovascular disease. (PubMed id 11551873) 2 , 9 Kramers C.... Adema G.J. (2001) Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis. (PubMed id 19021774) 1 , 9 Rushworth C.A....Turner A.J. (2008) Angiotensin-converting enzyme 2 (ACE2), but not ACE, is preferentially localized to the apical surface of polarized kidney cells. (PubMed id 16166094) 1 , 9 Warner F.J....Turner A.J. (2005) [Studies on ACE gene insertion/deletion polymorphism, serum ACE activity, and diabetic retinopathy in type II diabetic patients] (PubMed id 11938734) 4, 9 Liao L....Fan C. (1999) Angiotensin-converting enzyme inhibition by perindopr il in the treatment of cardiovascular disease. (PubMed id 19379059) 7, 9 Brugts J.J....Simoons M.L. (2009) No evidence for association between the renin-angiote nsin-aldosterone system and otosclerosis in a large Belgian-Dutch population. (PubMed id 19503013) 1 , 9 Schrauwen I....Van Camp G. (2009) Urinary mRNA expression of ACE and ACE2 in human type 2 diabetic nephropathy. (PubMed id 18389211) 1 , 9 Wang G....Szeto C.C. (2008) Terminating the stress: peripheral peptidolysis of proopiomelanocortin-derived regulatory hormones by the dermal microvascular endothelial cell extracellular peptidases neprilysin and angiotensin-converting enzyme. (PubMed id 17363457) 1 , 9 Scholzen T.E....Luger T.A. (2007) Role of some vasoactive mediators in patients with erectile dysfunction: their relationship with angiotensin-converting enzyme and growth hormone. (PubMed id 14671660) 1 , 9 Hamed E.A....Hamed S.A. (2003) Association between angiotensin-converting enzyme gene polymorphisms and regression of left ventricular hypertrophy in patients treated with angiotensin-converting enzyme inhibitors. (PubMed id 10335726) 4, 9 Kohno M....Yoshikawa J. (1999) Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with increased plasma angiotensin-converting enzyme activity but not with increased risk for myocardial infarction and coronary artery disease. (PubMed id 8644984) 4, 9 Winkelmann B.R....Marz W. (1996) Effect of ACE insertion/deletion and 12 other polymor phisms on clinical outcomes and response to treatment in the LIFE study. (PubMed id 20065889) 1 , 9 Nordestgaard B.G....Os I. (2010) Albumin caused the increasing production of angiotensin II due to the dysregulation of ACE/ACE2 expression in HK2 cells. (PubMed id 19141296) 1 , 9 Liu B.C....Xu L.M. (2009) The role of ace gene polymorphism in the development of angioedema secondary to angiotensin converting enzyme inhibitors and angiotensin II receptor blockers. (PubMed id 18680700) 1 , 9 Gulec M....Karaayvaz M. (2008) ACE I/D polymorphism in Korean patients with ischemic stroke and silent brain infarction. (PubMed id 17922891) 1 , 9 Hong S.H....Kim N.K. (2008) Evaluation of the angiotensin-converting enzyme insertion/deletion polymorphism and the risk of ischaemic stroke. (PubMed id 16446094) 1 , 9 Tuncer N....Kara I. (2006) [The hemostasis parameters and ACE gene polymorphism in patients with essential hypertension treated with perindopril] (PubMed id 17131847) 1 , 9 Janczak-Bazan A. (2006) Polymorphisms in angiotensin II type 1 receptor and angiotensin I-converting enzyme genes and breast cancer risk among Chinese women in Singapore. (PubMed id 15498791) 1 , 9 Koh W.P....Yu M.C. (2005) [I/D polymorphism of angiotensin I converting enzyme gene and insulin resistance and some parameters of metabolic syndrome in patients with type 2 diabetes] (PubMed id 16789486) 1 , 9 Moleda P....Pilarska K. (2005) HLA-DRB1, -DQA1, and -DQB1 subtypes or ACE gene polymorphisms do not seem to be risk markers for severe retinopathy in younger Type 1 diabetic patients. (PubMed id 15019597) 1 , 9 Agardh E....Agardh C.D. (2004) Angiotensin-converting enzyme and p22(phox) polymorphisms and the risk of coronary heart disease in a low-risk Spanish population. (PubMed id 15193812) 1 , 9 Mata-Balaguer T....Ruiz-Rejon F. (2004) Ectopeptidases are differentially expressed in hepatocellular carcinomas. (PubMed id 14767532) 1 , 9 Rocken C....Lendeckel U. (2004) Epistatic interaction between variations in the angiotensin I converting enzyme and angiotensin II type 1 receptor genes in relation to extent of coronary atherosclerosis. (PubMed id 12975417) 4, 9 Ye S....Simpson I. (2003) Effect of angiotensin-converting enzyme inhibition on restenosis after coronary stenting. (PubMed id 12521626) 1 , 9 Ribichini F....Uslenghi E. (2003) Quinapril: a further update of its pharmacology and t herapeutic use in cardiovascular disorders. (PubMed id 11817979) 7, 9 Culy C.R. and Jarvis B. (2002) Angiotensin-converting enzyme activity and the ACE Alu polymorphism in autosomal dominant polycystic kidney disease. (PubMed id 11733623) 1 , 9 Schiavello T....Thomas M. (2001) Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass. (PubMed id 8598840) 4, 9 Lindpaintner K....Levy D. (1996) Angiotensin I-converting enzyme gene polymorphism is associated with myocardial infarction, but not with retinopathy or nephropathy, in NIDDM. (PubMed id 7555560) 4, 9 Fujisawa T....Higaki J. (1995) Lack of association between angiotensin converting enzyme gene insertion/deletion polymorphism and stroke. (PubMed id 8903617) 4, 9 Ueda S....Lees K.R. (1995) Endothelial nitric oxide synthase, angiotensin-conver ting enzyme and angiotensinogen gene polymorphisms in hypertensive disorders of pregnancy. (PubMed id 20186148) 1 , 9 Aggarwal P.K....Jha V. (2010) Lack of association between renin-angiotensin system (RAS) polymorphisms and hypertension in Tunisian type 2 diabetics. (PubMed id 20415212) 1 , 9 Arfa I....Abdelhak S. (2010) Angiotensin-converting enzyme (ACE) and ACE2 levels in the cerebrospinal fluid of patients with multiple sclerosis. (PubMed id 19136547) 1 , 9 Kawajiri M....Kira J.I. (2009) Functional polymorphisms in ACE and CYP11B2 genes and atrial fibrillation in patients with hypertensive heart disease. (PubMed id 19117407) 1 , 9 Huang M....He J. (2009) Polymorphisms of angiotensin-converting enzyme (ACE) and ACE2 are not associated with orthostatic blood pressure dysregulation in hy pertensive patients. (PubMed id 19684612) 1 , 9 Fan X.H....Hui R.T. (2009) Genetic variation in the renin-angiotensin system modifies the beneficial effects of ACE inhibitors on the risk of diabetes mellitus among hypertensives. (PubMed id 18563171) 1 , 9 Bozkurt O....Klungel O.H. (2008) Association of angiotensin I-converting enzyme gene polymorphisms with aspirin intolerance in asthmatics. (PubMed id 18727619) 1 , 9 Kim T.H....Shin H.D. (2008) Angiotensin converting enzyme gene polymorphism (insertion/deletion) and hypertension in adult Asian Indians: a population-based study from Calcutta, India. (PubMed id 19130799) 1 , 9 Das M....Ghosh A. (2008) ACE gene polymorphism and losartan treatment in type 2 diabetic patients with nephropathy. (PubMed id 18199798) 1 , 9 Parving H.H....Brenner B.M. (2008) Role of genetic polymorphisms in ACE and TNF-alpha gene in sarcoidosis: a meta-analysis. (PubMed id 17768594) 1 , 9 Medica I....Peterlin B. (2007) Angiotensin-converting enzyme gene polymorphism in chronic allograft nephropathy. (PubMed id 16797293) 1 , 9 Biselli P.M....Pavarino-Bertelli E.C. (2006) Insertion/deletion polymorphism of angiotensin I converting enzyme gene and left ventricular hypertrophy in patients with type 2 diabetes mellitus. (PubMed id 17054027) 1 , 9 Moleda P....Goracy I. (2006) Circulating activities of angiotensin-converting enzyme, its homolog, angiotensin-converting enzyme 2, and neprilysin in a family study. (PubMed id 17000927) 1 , 9 Rice G.I....Hooper N.M. (2006) [Association of polymorphic markers I/D of gene ACE and A1166C of gene AT2R1 with ischemic chronic heart failure in the Russian and Tatar populations of Bashkortostan Republic] (PubMed id 17326392) 1 , 9 Gubaev K.I....Mustafina O.E. (2006) [Allelic variants of genes: angiotensin I-converting enzyme (ACE), angiotensin-II type 1 receptor (AT1R), methylenetetrahydrofolate reductase and left ventricular mass in patients with myocardial infarction] (PubMed id 17274465) 1 , 9 Goracy J....Ciechanowicz A. (2006) Renin-angiotensin system gene polymorphisms: association with susceptibility to Henoch-Schonlein purpura and renal involvement. (PubMed id 16521052) 1 , 9 Ozkaya O....Hasanoglu E. (2006) No association between variants in the ACE and angiotensin II receptor 1 genes and acute mountain sickness in Nepalese pilgrims to the Janai Purnima Festival at 4380 m. (PubMed id 17173513) 1 , 9 Koehle M.S....Rupert J.L. (2006) Angiotensin converting enzyme gene polymorphism in Indian children with steroid sensitive nephrotic syndrome. (PubMed id 16272677) 1 , 9 Patil S.J....Agrawal S. (2005) ACE insert/delete polymorphism and atherosclerosis. (PubMed id 15694930) 1 , 9 Scheer W.D....Strong J.P. (2005) Hypoxia-driven proliferation of human pulmonary artery fibroblasts: cross-talk between HIF-1alpha and an autocrine angiotensin system. (PubMed id 15718424) 1 , 9 Krick S....Rose F. (2005) Effects of genetic polymorphisms of the renin-angiotensin system in children with nephrotic syndrome. (PubMed id 16525944) 1 , 9 Tabel Y....Yilmaz E. (2005) Angiotensin-I converting enzyme insertion/deletion polymorphism and its association with diabetic nephropathy: a meta-analysis of studies reported between 1994 and 2004 and comprising 14,727 subjects. (PubMed id 15830182) 1 , 9 Ng D.P....Chia K.S. (2005) Effects of ACE gene insertion/deletion polymorphism on response to spironolactone in patients with chronic heart failure. (PubMed id 15121491) 1 , 9 Cicoira M....Zardini P. (2004) Impact of angiotensin-converting enzyme gene polymorphism on neurohormonal responses to high- versus low-dose enalapril in advanced heart failure. (PubMed id 15523323) 1 , 9 Tang W.H....Fowler M.B. (2004) Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. (PubMed id 15283675) 1 , 9 Rice G.I.... Hooper N.M. (2004) Angiotensin-converting enzyme gene polymorphism, left ventricular remodeling, and exercise capacity in strength-trained athletes. (PubMed id 15799176) 1 , 9 Kasikcioglu E....Peker I. (2004) [The relationship of angiotensin I-converting enzyme gene polymorphism with diabetic retinopathy and diabetes myocardial infarction] (PubMed id 15192839) 1 , 9 Wu S.S....Yi H.L. (2004) The ACE gene I/D polymorphism is not associated with the blood pressure and cardiovascular benefits of ACE inhibition. (PubMed id 12925557) 1 , 9 Harrap S.B....Woodward M. (2003) Cardiac hypertrophy and remodeling in relation to ACE and angiotensinogen genes genotypes in Chinese dialysis patients. (PubMed id 12675870) 1 , 9 Wang A.Y....Sanderson J. (2003) Interacting effects of gender and genotype on blood pressure response to hydrochlorothiazide. (PubMed id 12371972) 1 , 9 Schwartz G.L....Boerwinkle E. (2002) Does age, sex, or ACE genotype affect glucose and insulin responses to strength training? (PubMed id 11796676) 1 , 9 Hurlbut D.E....Hurley B.F. (2002) Toward an optimal joint recognition of the S1' subsites of endothelin converting enzyme-1 (ECE-1), angiotensin converting enzyme (ACE), and neutral endopeptidase (NEP). (PubMed id 11906289) 1 , 9 Inguimbert N....Roques B.P. (2002) The D-allele of the ACE polymorphism is related to increased QT dispersion in 609 patients after myocardial infarction. (PubMed id 11286523) 1 , 9 Jeron A....Holmer S. (2001) Angiotensin-converting enzyme (ACE) gene polymorphisms and familial occurrence of sarcoidosis. (PubMed id 11168787) 1 , 9 Schurmann M....Schwinger E. (2001) Association between ACE gene polymorphism and diabetic nephropathy in South Indian patients. (PubMed id 11867868) 4, 9 Viswanathan V....Sharma K. (2001) Association of angiotensin I converting enzyme gene polymorphism with reflux nephropathy in children. (PubMed id 10971153) 4, 9 Park H.W....Choi Y. (2000) Angiotensin converting enzyme (ACE) gene polymorphism in sarcoidosis in relation to associated autoimmune diseases. (PubMed id 10672133) 4, 9 Papadopoulos K.I....Hallengren B. (2000) Association of essential hypertension in elderly Japanese with I/D polymorphism of the angiotensin-converting enzyme (ACE) gene. (PubMed id 11043512) 4, 9 Yoshida K....Umemura S. (2000) Association of the ACE gene polymorphism with the progression of autosomal dominant polycystic kidney disease. (PubMed id 10983692) 4, 9 Lee K.B....Lee C.C. (2000) Association of angiotensin-converting enzyme gene polymorphism and renal pathology in Japanese children with IgA nephropathy. (PubMed id 10404693) 4, 9 Asano T....Yamamoto M. (1999) [Angiotensin converting enzyme (ACE) gene polymorphism in a diabetic cohort and diabetic nephropathy] (PubMed id 10955109) 4, 9 Levinson O....Yagil Y. (1999) Angiotensin I-converting enzyme gene polymorphisms: relationship to nephropathy in patients with non-insulin dependent diabetes mellitus. (PubMed id 9727375) 4, 9 Grzeszczak W....Zukowska-Szczechowska E. (1998) [Is PstI polymorphism of the angiotensin I converting enzyme gene associated with nephropathy development in non-insulin-dependent diabetes mellitus (preliminary study)] (PubMed id 9499204) 4, 9 Grzeszczak W....Lacka B. (1997) Association between angiotensin converting enzyme gene polymorphism and clinical features in autosomal dominant polycystic kidney disease. (PubMed id 9180368) 4, 9 Uemasu J....Morio S. (1997) Angiotensin I-converting enzyme and angiotensinogen gene polymorphisms in non-insulin-dependent diabetes mellitus. Lack of relationship with diabetic nephropathy and retinopathy in a Caucasian Mediterranean population. (PubMed id 9258285) 4, 9 Gutierrez C....Richart C. (1997) The deletion polymorphism of the angiotensin I-converting enzyme gene is associated with target organ damage in essential hypertension. (PubMed id 8989733) 4, 9 Pontremoli R....Deferrari G. (1996) Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, and diabetic retinopathy in subjects with IDDM and NIDDM. (PubMed id 8582133) 4, 9 Nagi D.K....Grant P.J. (1995) Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus. (PubMed id 8170965) 4, 9 Ruiz J....Froguel P. (1994) Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction. (PubMed id 20230274) 1 , 9 Kulminski A.M....Yashin A.I. (2010) ACE and AGTR1 polymorphisms and left ventricular hype rtrophy in endurance athletes. (PubMed id 19997001) 1 , 9 Di Mauro M....Gallina S. (2010) ACE D/I polymorphism, migraine, and cardiovascular disease in women. (PubMed id 19221299) 1 , 9 SchA1rks M....Kurth T. (2009) Angiotensin-converting enzyme (ACE), angiotensinogen (AGT), and angiotensin II type 1 receptor (AT1R) gene polymorphisms in generalized aggressive periodontitis. (PubMed id 19162259) 1 , 9 GA1rkan A....Berdeli A. (2009) Role of the ACE ID and MTHFR C677T polymorphisms in genetic susceptibility of migraine in a north Indian population. (PubMed id 19081115) 1 , 9 Joshi G....Mittal B. (2009) ACE Variants Interact with the RAS Pathway to Confer Risk and Protection against Type 2 Diabetic Nephropathy. (PubMed id 19108684) 1 , 9 Ahluwalia T.S....Khullar M. (2009) Association of angiotensin-converting enzyme activity and polymorphism with echocardiographic measures in familial and nonfamilial hypertrophic cardiomyopathy. (PubMed id 19390744) 1 , 9 Buck P.C....Mady C. (2009) Genetic analysis of Factor XII and bradykinin catabolic enzymes in a family with estrogen-dependent inherited angioedema. (PubMed id 19178938) 1 , 9 Duan Q.L....Rouleau G.A. (2009) Cost-effectiveness of ACE inhibitor therapy to preven t dialysis in nondiabetic nephropathy: influence of the ACE insertion/deletion polymorphism. (PubMed id 19696696) 1 , 9 Vegter S....Postma M.J. (2009) Identification of specific angiotensin-converting enz yme variants and haplotypes that confer risk and protection against type 2 diab etic nephropathy. (PubMed id 19787680) 1 , 9 Ezzidi I....Almawi W.Y. (2009) [Comparative genetic analysis of different forms of low-renin arterial hypertension] (PubMed id 18856058) 1 , 9 Chikhladze N.M....Favorova O.O. (2008) The D allele of angiotensin I-converting enzyme gene insertion/deletion polymorphism is associated with the severity of atherosclerosis. (PubMed id 18298340) 1 , 9 Niemiec P....Wita K. (2008) [Study on the association of predisposing genes with essential hypertension among Kazakhs ethnic group in Xinjiang] (PubMed id 19103106) 1 , 9 Chen X.D....Jin L. (2008) Combined 'pro-atherosclerotic' variants of the ACE and APOE genes increase the risk of the coronary artery disease associated with the presence of cigarette smoking. (PubMed id 19157170) 1 , 9 Zak I....Krauze J. (2008) Association of the angiotensinogen M235T and angiotensin-converting enzyme insertion/deletion gene polymorphisms in Turkish type 2 diabetic patients with and without nephropathy. (PubMed id 18413162) 1 , 9 Eroglu Z....Tuzun M. (2008) Angiotensin-converting enzyme gene insertion/deletion polymorphism in migraine patients. (PubMed id 18366776) 1 , 9 Tronvik E....Schrader H. (2008) Influence of the ACE gene insertion/deletion polymorphism on insulin sensitivity and impaired glucose tolerance in healthy subjects. (PubMed id 18235053) 1 , 9 Bonnet F....Walker M. (2008) Lack of association between the angiotensin-converting enzyme gene (I/D) polymorphism and diabetic nephropathy in Tunisian type 2 diabetic patients. (PubMed id 18404607) 1 , 9 Arfa I....Abdelhak S. (2008) Heamostatic and genetic predisposing factors for stro ke in children with sickle cell anemia. (PubMed id 20306667) 1 , 9 Mourad H....Rowisha M. (2008) No association found between the insertion/deletion of a 287-bp alu repeat sequence within intron 16 of the angiotensin-I-converting enzyme (ACE) gene in Mexican patients and binary restenosis after coronary stenting. (PubMed id 18706898) 1 , 9 Martinez-Rios M.A....Vargas-Alarcon G. (2008) [The relationship between the effect of amlodipine on carotid intimal-medial thickness and angiotensin converting enzyme genotypes in elderly hypertensive patients] (PubMed id 19100063) 1 , 9 Zhai L.H....Hu Y.H. (2008) ACE gene polymorphism and cardiac structure in patients with insulin resistance. (PubMed id 18347926) 1 , 9 Akin F....Gur S. (2008) Prognostic Value of the Insertion/Deletion polymorphism of Angiotensin I Converting Enzyme gene in type 2 diabetic subjects: results from the DIABHYCAR, DIAB2NEPHROGENE & SURDIAGENE studies. (PubMed id 18523145) 1 , 9 Hadjadj S....Marre M. (2008) Angiotensinogen and ACE gene polymorphisms and risk of atrial fibrillation in the general population. (PubMed id 18496132) 1 , 9 Ravn L.S....Tybjaerg-Hansen A. (2008) RAS and MTHFR gene polymorphisms in a healthy exercise-trained population: association with the MTHFR (TT) genotype and a lower hemoglobin level. (PubMed id 17024648) 1 , 9 Fortunato G....Buono P. (2007) Role of PC-1 and ACE genes on insulin resistance and cardiac mass in never-treated hypertensive patients. Suggestive evidence for a digenic additive modulation. (PubMed id 17367703) 1 , 9 Perticone F....Trischitta V. (2007) Possible association of ACE gene I/D polymorphism with blood pressure--lowering response to hydrochlorothiazide. (PubMed id 18188985) 1 , 9 Zhou Y....Liu G.F. (2007) Association of angiotensin-converting enzyme/DD genotype with sarcoidosis susceptibility in Slovenian patients. (PubMed id 18049432) 1 , 9 Salobir B....Peterlin B. (2007) Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trial. (PubMed id 17885551) 1 , 9 Bhatnagar V....Lipkowitz M.S. (2007) Low-density lipoproteins induce the renin-angiotensin system and their receptors in human endothelial cells. (PubMed id 17992634) 1 , 9 Catar R.A....Morawietz H. (2007) The two fACEs of the tissue renin-angiotensin systems: implication in cardiovascular diseases. (PubMed id 17504232) 1 , 9 Lazartigues E....Lavoie J.L. (2007) Deletion polymorphism of the angiotensin I-converting enzyme gene in elderly patients with coronary heart disease. (PubMed id 17598398) 1 , 9 Markovic B.B....Markovic M. (2007) Angiotensin converting enzyme genotype affects development and course of sarcoidosis in Asian Indians. (PubMed id 18496980) 1 , 9 Tahir M....Mishra H.K. (2007) Association of ACE genotype and predominantly diastolic hypertension: a preliminary study. (PubMed id 17487825) 1 , 9 Jimenez P.M....Orias M. (2007) Polymorphisms in genes of the renin-angiotensin system and cerebral small vessel disease. (PubMed id 17124396) 1 , 9 Gormley K....Markus H.S. (2007) Angiotensin-converting enzyme gene polymorphism and allele frequencies in the Lebanese population: prevalence and review of the literature. (PubMed id 17103020) 1 , 9 Sabbagh A.S....Mahfouz R.A. (2007) Polymorphisms of ACE2 gene are associated with essential hypertension and antihypertensive effects of Captopril in women. (PubMed id 17473847) 1 , 9 Fan X....Hui R. (2007) Combinational effect of genes for the renin-angiotensin system in conferring susceptibility to diabetic nephropathy. (PubMed id 17143591) 1 , 9 Osawa N....Maeda S. (2007) A disease haplotype for advanced nephropathy in type 2 diabetes at the ACE locus. (PubMed id 16936219) 1 , 9 Ng D.P....Krolewski A.S. (2006) Association of angiotensin I-converting enzyme gene insertion/deletion polymorphism and IgA nephropathy: a meta-analysis. (PubMed id 17124384) 1 , 9 Yong D....Chao S.H. (2006) The relationship between ACE insertion/deletion polymorphism and coronary artery disease with or without myocardial infarction. (PubMed id 16303122) 1 , 9 Seckin D....Ozbay Y. (2006) Antiproteinuric effect of losartan in non-diabetic renal disease is not dependent on ACE insertion/deletion polymorphism. (PubMed id 16960460) 1 , 9 Park H.C....Han D.S. (2006) Influence of ACE I/D gene polymorphism in the progres sion of renal failure in autosomal dominant polycystic kidney disease: a meta-a nalysis. (PubMed id 16935894) 1 , 9 Pereira T.V....Krieger J.E. (2006) The molecular basis for the selection of captopril ci s and trans conformations by angiotensin I converting enzyme. (PubMed id 16889963) 7, 9 Tzakos A.G....Gerothanassis I.P. (2006) Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism. (PubMed id 16924268) 1 , 9 Baghai T.C....Bondy B. (2006) Association of ACE, ACE2 and UTS2 polymorphisms with essential hypertension in Han and Dongxiang populations from north-western China. (PubMed id 16866021) 1 , 9 Yi L....Zhang D.L. (2006) Increased expression of the renin-angiotensin system and mast cell density but not of angiotensin-converting enzyme II in late stages of human heart failure. (PubMed id 16962475) 1 , 9 Batlle M....Jimenez W. (2006) Monitoring neuropeptide-specific proteases: processing of the proopiomelanocortin peptides adrenocorticotropin and alpha-melanocyte-stimulating hormone in the skin. (PubMed id 16984256) 1 , 9 Konig S....Scholzen T.E. (2006) [Polymorphism of angiotensin converting enzyme in Han populations and its relevance to the severity of coronary atherosclerosis] (PubMed id 16764031) 1 , 9 Shi Y.P....Xu G. (2006) Human physiologically based pharmacokinetic model for ACE inhibitors: ramipril and ramiprilat. (PubMed id 16398929) 7, 9 Levitt D.G. and Schoemaker R.C. (2006) The relationship between angiotensin converting enzyme gene polymorphism, coronary artery disease, and stent restenosis: the role of angiotensin converting enzyme inhibitors in stent restenosis in patients with diabetes mellitus. (PubMed id 16272779) 1 , 9 Guneri S....Bozdemir V. (2005) Genotypic interactions of renin-angiotensin system genes in myocardial infarction. (PubMed id 16061119) 1 , 9 Araujo M.A....Silva H.D. (2005) Effect of genetic variation on therapy with angiotensin converting enzyme inhibitors or angiotensin receptor blockers in dialysis patients. (PubMed id 15946912) 1 , 9 Boger C.A....Kramer B.K. (2005) [I/D relationship between polymorphism of ACE gene and progression of chronic glomerulonephritis] (PubMed id 16078593) 1 , 9 Kaliev R.R....Mirrakhimov M.M. (2005) The influence of angiotensin-converting enzyme gene of donor and recipient on the function of transplanted kidney. (PubMed id 15848522) 1 , 9 Kabat-Koperska J....Ciechanowski K. (2005) Polymorphism of the ACE Gene in dialysis patients: overexpression of DD genotype in type 2 diabetic end-stage renal failure patients. (PubMed id 16385653) 1 , 9 Park H.C....Ha S.K. (2005) Effect of 24-week treatment with telmisartan on myocardial structure and function: relationship to insertion/deletion polymorphism of the angiotensin-converting enzyme gene. (PubMed id 16222898) 1 , 9 Conrady A.O....Panov A.V. (2005) Deletion/Deletion genotype of angiotensin-I converting enzyme gene is not associated with coronary artery disease in caucasians with type 2 diabetes. (PubMed id 16117314) 1 , 9 Zorc-Pleskovic R....Milutinovic A. (2005) Insertion/deletion polymorphism of the angiotensin-converting enzyme gene and preeclampsia in Japanese patients. (PubMed id 16052407) 1 , 9 Kobashi G....Kondo K. (2005) [Influence of angiotensin-converting enzyme gene polymorphism on the anti-proteinuria efficacy of angiotensin-converting enzyme inhibitor in Han nationality of southern Sichuan province in China] (PubMed id 15793787) 1 , 9 Liu J....Peng B. (2005) Carotid artery intima-media thickness and angiotensin-converting enzyme gene polymorphism in the offspring of parents with premature stroke. (PubMed id 15858957) 1 , 9 Varda N.M....Gregoric A. (2005) Polymorphisms of the angiotensin converting enzyme and angiotensin II type 1 receptor genes and renal scarring in non-uropathic children with recurrent urinary tract infection. (PubMed id 16109085) 1 , 9 Ece A....Budak T. (2005) Association of ACE polymorphisms with left ventricular hypertrophy. (PubMed id 16136003) 1 , 9 Saeed M....Frossard P.M. (2005) Genetic variation at the ACE gene is associated with persistent microalbuminuria and severe nephropathy in type 1 diabetes: the DCCT/EDIC Genetics Study. (PubMed id 15793268) 1 , 9 Boright A.P....Zinman B. (2005) ACE gene polymorphism, left ventricular geometry, and mortality in diabetic patients with end-stage renal disease. (PubMed id 15036826) 1 , 9 Sakka Y....Iwamoto Y. (2004) [Genetic polymorphism of the angiotensin I converting enzyme and morbi-mortality after myocardial infarction] (PubMed id 15002705) 1 , 9 Filippi-Codaccioni E....Hamon M. (2004) Vascular effects of quinapril completely depend on ACE insertion/deletion polymorphism. (PubMed id 15526248) 1 , 9 Voors A.A....van Gilst W.H. (2004) Angiotensin-I converting enzyme gene polymorphism in Turkish type 2 diabetic patients. (PubMed id 15365253) 1 , 9 Arzu Ergen H....Isbir T. (2004) Association study of the I/D polymorphism and plasma angiotensin-converting enzyme (ACE) as risk factors for stent restenosis. (PubMed id 15101817) 1 , 9 Ribichini F....Piazza A. (2004) [The relationship between angiotensin-converting enzyme gene polymorphism and heart rate variability in cerebral stroke] (PubMed id 15079800) 1 , 9 Wang Y.M....Yang Z.C. (2004) Angiotensin converting enzyme genotype influences the response to the angiotensin II receptor antagonist losartan in patients with hypertension. (PubMed id 15080371) 1 , 9 Nakamura Y....Yamada Y. (2004) Increased cardiovascular risk in long-term hemodialysis patients carrying deletion allele of ACE gene polymorphism. (PubMed id 15332219) 1 , 9 Ishimitsu T....Matsuoka H. (2004) Lack of an association between angiotensin-converting enzyme gene insertion/deletion polymorphism and ischaemic stroke. (PubMed id 15007267) 1 , 9 Karagiannis A....Zamboulis C. (2004) [The relationship between polymorphism of angiotensin converting enzyme gene and cough caused by angiotensin converting enzyme inhibitors] (PubMed id 12901825) 1 , 9 Yang S.M....Miao Y.D. (2003) Angiotensin-converting enzyme polymorphism gene and evolution of nephropathy to end-stage renal disease. (PubMed id 15012717) 1 , 9 Ortiz M.A....Pou J.M. (2003) [I/D gene polymorphism of the angiotensin-converting enzyme and left ventricular hypertrophy. Response to converting enzyme inhibitors] (PubMed id 12945221) 1 , 9 Rugale C....Mimran A. (2003) [Polymorphic markers I/D and G7831A of angiotensin-I-converting enzyme gene and left ventricular hypertrophy in patients with essential hypertension] (PubMed id 12891272) 1 , 9 Brazhnik V.A....Sidorenko B.A. (2003) The higher immunoreactivity to ACE (angiotensin converting enzyme) in patients with type 2 diabetes mellitus than in non-diabetic individuals. (PubMed id 12803241) 1 , 9 Nishida S....Ichihara K. (2003) Long-term renoprotective effects of losartan in diabetic nephropathy: interaction with ACE insertion/deletion genotype? (PubMed id 12716812) 1 , 9 Andersen S....Parving H.H. (2003) [The role of polymorphic variants of renin-angiotensin system genes in the development of ischemic stroke in Moscow population] (PubMed id 12830507) 1 , 9 Skvortsov V.I....Shamalov N.A. (2003) The influence of the ACE ( I/D) polymorphism on systemic and renal vascular responses to angiotensins in normotensive, normoalbuminuric Type 1 diabetes mellitus. (PubMed id 12856080) 1 , 9 Luik P.T....Navis G.J. (2003) Angiotensin-converting enzyme gene polymorphism and erythropoietin requirement. (PubMed id 12713075) 1 , 9 Varagunam M....Yaqoob M.M. (2003) Structural basis of the lisinopril-binding specificity in N- and C-domains of human somatic ACE. (PubMed id 12901857) 1 , 9 Fernandez J.H....Neshich G. (2003) Coronary heart disease, hypertension, and angiotensinogen gene variants in Indian population. (PubMed id 12938141) 1 , 9 Nair K.G....Dalal J.J. (2003) Angiotensin-converting enzyme inhibitor withdrawal and ACE gene polymorphism. (PubMed id 14579936) 1 , 9 Nonoguchi H....Tomita K. (2003) [Genotypes of ACE gene in Kazakh and Uygur patients with ischemic heart disease] (PubMed id 11855311) 1 , 9 Baitasova N.B. and Rysmendiev A.Z.h. (2002) Polymorphisms of ACE-1 and MTHFR genes and genetic susceptibility of ischemic strok. (PubMed id 12194796) 1 , 9 Li C....Liu J. (2002) ACE gene polymorphism and renal scarring in primary vesicoureteric reflux. (PubMed id 12478352) 1 , 9 Haszon I....Turi S. (2002) [Polymorphism of the angiotensin-converting enzyme gene in cardiovascular pathology] (PubMed id 12442545) 1 , 9 Tseluiko V.I....Liashenko A.V. (2002) Clinical pharmacokinetics and selective pharmacodynam ics of new angiotensin converting enzyme inhibitors: an update. (PubMed id 11929321) 7, 9 Song J.C. and White C.M. (2002) Enhanced responses of blood pressure, renal function, and aldosterone to angiotensin I in the DD genotype are blunted by low sodium intake. (PubMed id 11912262) 1 , 9 van der Kleij F.G....Navis G. (2002) Interdependent effect of angiotensin-converting enzyme and platelet-activating factor acetylhydrolase gene polymorphisms on the progression of immunoglobulin A nephropathy. (PubMed id 12220450) 1 , 9 Yoon H.J....Kim Y.S. (2002) An interaction between systolic blood pressure and angiotensin-converting enzyme gene polymorphism on carotid atherosclerosis. (PubMed id 12484511) 1 , 9 Kawamoto R....Miki T. (2002) Polymorphism of renin-angiotensin system genes in dialysis patients--association with cerebrovascular disease. (PubMed id 12454231) 1 , 9 Losito A....Jeffery S. (2002) Different aortic reflection wave responses following long-term angiotensin-converting enzyme inhibition and beta-blocker in essential hypertension. (PubMed id 11903319) 1 , 9 Pannier B.M....London G.M. (2001) Polymorphisms of renin-angiotensin system genes in childhood IgA nephropathy. (PubMed id 11354780) 1 , 9 Maruyama K....Yoshikawa N. (2001) Relationship of angiotensin converting enzyme genotype with serum triglyceride concentration in stroke patients. (PubMed id 11720769) 1 , 9 del Ser T....Cemillan C. (2001) The ACE gene polymorphism and cough threshold for capsaicin after cilazapril usage. (PubMed id 11217909) 1 , 9 Takahashi T....Kawakami Y. (2001) Analysis of the postulated interaction between the angiotensin II sub-type 1 receptor gene A1166C polymorphism and the insertion/deletion polymorphism of the angiotensin converting enzyme gene on risk of myocardial infarction. (PubMed id 11137090) 1 , 9 Steeds R.P....Samani N.J. (2001) Predictors of coronary in-stent restenosis: importance of angiotensin-converting enzyme gene polymorphism and treatment with angiotensin-converting enzyme inhibitors. (PubMed id 11691520) 1 , 9 Jorgensen E....Reiber J.H. (2001) Left ventricular hypertrophy with exercise and ACE gene insertion/deletion polymorphism: a randomized controlled trial with losartan. (PubMed id 11208681) 1 , 9 Myerson S.G....Pennell D.J. (2001) Angiotensin II type-I receptor and ACE polymorphisms and risk of myocardial infarction in men and women. (PubMed id 11122322) 1 , 9 Kee F....Evans A.E. (2000) Insertion/deletion polymorphism of the angiotensin I-converting enzyme gene is not associated with restenosis after coronary stent placement. (PubMed id 10889131) 4, 9 Koch W....Schomig A. (2000) Antihypertensive treatment modulates the association between the D/I ACE gene polymorphism and left ventricular hypertrophy: a meta-analysis. (PubMed id 10918550) 4, 9 Kuznetsova T....Fagard R. (2000) Insertion/deletion polymorphism in the angiotensin-converting enzyme gene in myocardial infarction survivors. (PubMed id 11208361) 1 , 9 Hubacek J.A....Poledne R. (2000) Lack of association between ACE gene polymorphism and left ventricular hypertrophy in essential hypertension. (PubMed id 10673731) 4, 9 Gomez-Angelats E....Coca A. (2000) Insertion/deletion polymorphism in ACE gene is not associated with renal progression in Japanese patients with IgA nephropathy. (PubMed id 10793025) 4, 9 Suzuki S....Tomino Y. (2000) The relationship of angiotensin-converting enzyme gene to essential hypertension and drug treatment in Chongqing. (PubMed id 11024215) 1 , 9 Liu Q....Wang X. (2000) Association of ACE I/D polymorphism with cardiovascular risk factors. (PubMed id 11071385) 4, 9 Uemura K....Miki T. (2000) Lack of association of angiotensin-converting enzyme (DD/II) and angiotensinogen M235T gene polymorphism with renal function among Chinese patients with type II diabetes. (PubMed id 10352194) 4, 9 Wong T.Y....Li P.K. (1999) The deletion genotype of the angiotensin I-converting enzyme is associated with an increased vascular reactivity in vivo and in vitro. (PubMed id 10483967) 4, 9 Henrion D....Levy B.I. (1999) Polymorphism in the angiotensin converting enzyme but not in the angiotensinogen gene is associated with hypertension and type 2 diabetes: the Skaraborg Hypertension and diabetes project. (PubMed id 10608470) 4, 9 Bengtsson K....Groop L. (1999) Angiotensin-converting enzyme and angiotensin II receptor 1 polymorphisms: association with early coronary disease. (PubMed id 9893731) 4, 9 Alvarez R....Coto E. (1998) Angiotensin-converting enzyme insertion/deletion polymorphism and diabetic albuminuria in patients with NIDDM followed Up for 9 years. (PubMed id 9730698) 4, 9 Huang X.H....Lehtimaki T. (1998) Renal ACE immunohistochemical localization in NIDDM patients with nephropathy. (PubMed id 9469501) 4, 9 Mizuiri S....Hasegawa A. (1998) Calorimetric analysis of lisinopril binding to angiot ensin I-converting enzyme. (PubMed id 9506845) 7, 9 TAcllez-Sanz R....BarA^n C. (1998) Interethnic differences in coronary heart disease mortality in 25 populations: association with the angiotensin-converting enzyme DD genotype frequency. (PubMed id 9920000) 4, 9 Young R.P....Sanderson J.E. (1998) [Association between ACE gene polymorphism and therapeutic responsiveness of ACEI in diabetic nephropathy] (PubMed id 10923445) 4, 9 Wang L....Hu W. (1998) Polymorphism of the angiotensin I-converting enzyme gene in diabetic nephropathy in type II diabetic patients with proliferative retinopathy. (PubMed id 9509566) 4, 9 Hanyu O....Shibata A. (1998) Excess of DD homozygotes in haemodialysed patients with type II diabetes. The Diabetic Nephropathy Study Group. (PubMed id 9075119) 4, 9 Schmidt S....Ritz E. (1997) Association of angiotensin I-converting enzyme gene polymorphism with myocardial ischemia and patency of infarct-related artery in patients with acute myocardial infarction. (PubMed id 9180106) 4, 9 Dakik H.A....Marian A.J. (1997) [Relationship between angiotensin 1 converting enzyme gene polymorphism and diabetic nephropathy] (PubMed id 9596955) 4, 9 Wu S....Weng Q. (1997) Lack of association of the angiotensin converting enzyme polymorphism with essential hypertension in a Chinese population. (PubMed id 9037328) 4, 9 Chiang F.T....Tseng Y.Z. (1997) Association between a polymorphism in the angiotensin-converting enzyme gene and microvascular complications in Japanese patients with NIDDM. (PubMed id 8720609) 4, 9 Doi Y....Fujishima M. (1996) Lack of association of angiotensin I-converting enzyme gene polymorphism and premature myocardial infarction in Mauritian Indians. (PubMed id 9147898) 4, 9 Ramasawmy R....Baligadoo S. (1996) U.K. Prospective Diabetes Study. XV: Relationship of renin-angiotensin system gene polymorphisms with microalbuminuria in NIDDM. (PubMed id 8587251) 4, 9 Dudley C.R....Ratcliffe P.J. (1995) Association of ACE gene polymorphisms with coronary artery disease in a northern area of Japan. (PubMed id 8558760) 4, 9 Takahashi K....Tomoike H. (1995) Association of ACE gene polymorphism and diabetic nephropathy? The Diabetic Nephropathy Study Group. (PubMed id 7783416) 4, 9 Schmidt S....Ritz E. (1995) Gene polymorphism but not catalytic activity of angiotensin I-converting enzyme is associated with coronary artery disease and myocardial infarction in low-risk patients. (PubMed id 7586243) 4, 9 Gardemann A....Haberbosch W. (1995) Insertion/deletion polymorphism in the angiotensin-I-converting enzyme gene is associated with coronary heart disease in IDDM patients with diabetic nephropathy. (PubMed id 7556981) 4, 9 Tarnow L....Borch-Johnsen K. (1995) Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy. (PubMed id 8177269) 4, 9 Schunkert H....Riegger G.A. (1994) Insertion/deletion (I/D) polymorphism at the locus for angiotensin I-converting enzyme and parental history of myocardial infarction. (PubMed id 8131300) 1 , 9 Bohn M....Berg K. (1993) Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. (PubMed id 1328889) 1 , 9 Cambien F....Ricard S. (1992) Association of a polymorphism of the angiotensin I-converting enzyme gene with essential hypertension. (PubMed id 1314601) 4, 9 Zee R.Y....Morris B.J. (1992) Alpha-adrenergic and angiotensin II pressor sensitivi ty in hypertensive patients treated with an angiotensin-converting enzyme inhib itor. (PubMed id 1382157) 7, 9 Rosendorff C....Kalliatakis B. (1992) Relationship between genetic polymorphisms of angiote nsin-converting enzyme and methylenetetrahydrofolate reductase as risk factors for type 2 diabetes in Tunisian patients. (PubMed id 19857476) 1 , 9 Mehri S....Hammami M. (2010) Angiotensin I-converting enzyme Gln1069Arg mutation i mpairs trafficking to the cell surface resulting in selective denaturation of t he C-domain. (PubMed id 20454656) 1 , 9 Danilov S.M....Minshall R.D. (2010) Angiotensin-converting enzyme gene polymorphism in ov erweight and obese Turkish patients with insulin resistance. (PubMed id 20070157) 1 , 9 Akin F....Guclu A. (2010) COC use, ACE/AGT gene polymorphisms, and risk of stro ke. (PubMed id 20300047) 1 , 9 Li Y....Shen H. (2010) Polymorphisms in NOS3, ACE and PAI-1 genes and risk o f spontaneous recurrent miscarriage in the Gaza Strip. (PubMed id 20134171) 1 , 9 Al Sallout R.J. and Sharif F.A. (2010) Causal relationship of susceptibility genes to ischem ic stroke: comparison to ischemic heart disease and biochemical determinants. (PubMed id 20161734) 1 , 9 Bentley P....Sharma P. (2010) Effect of angiotensin-converting enzyme gene insertio n/deletion polymorphism on steroid resistance in Egyptian children with idiopat hic nephrotic syndrome. (PubMed id 20418353) 1 , 9 Saber-Ayad M....Abdel-Shafy S. (2010) Migraine and coronary artery disease: an open study o n the genetic polymorphism of the 5, 10 methylenetetrahydrofolate (MTHFR) and a ngiotensin I-converting enzyme (ACE) genes. (PubMed id 20518725) 1 , 9 Pizza V....Capasso A. (2010) DD genotype of angiotensin-converting enzyme in type 2 diabetes mellitus with renal disease in Mexican Mestizos. (PubMed id 19207872) 1 , 9 Palomo-PiA+A^n S....Cruz M. (2009) Role of angiotensin converting enzyme, paraoxonase 1 55, 192 gene polymorphisms in syndrome X and coronary heart disease. (PubMed id 19579917) 1 , 9 Sesal C....Sayar N. (2009) [Complex analysis of genetic predisposition to ischem ic stroke in Russians] (PubMed id 19899640) 1 , 9 Parfenov M.G....Favorova O.O. (2009) Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study. (PubMed id 19057513) 1 , 9 SuonsyrjAo T....Hiltunen T.P. (2009) Elevated ACE activity is not associated with asthma, COPD, and COPD co-morbidity. (PubMed id 19423314) 1 , 9 Lee J....Dahl M. (2009) Angiotensin-converting enzyme gene does not contribute to genetic susceptibility to systemic sclerosis in European Caucasians. (PubMed id 19132786) 1 , 9 Wipff J....Allanore Y. (2009) ACE I/D polymorphism associated with abnormal atrial and atrioventricular conduction in lone atrial fibrillation and structural hear t disease: implications for electrical remodeling. (PubMed id 19648063) 1 , 9 Watanabe H....Darbar D. (2009) Relationship between angiotensin-converting enzyme gene polymorphism and body composition, functional performance, and blood biomarkers in advanced cancer patients. (PubMed id 19258445) 1 , 9 Vigano A....Morais J.A. (2009) Genetic variation in angiotensin-converting enzyme-re lated pathways associated with sudden cardiac arrest risk. (PubMed id 19716087) 1 , 9 Sotoodehnia N....Siscovick D.S. (2009) Genetic Risk Factors for Arterial Ischemic Stroke in Children: A Possible MTHFR and eNOS Gene-Gene Interplay? (PubMed id 19372095) 1 , 9 Djordjevic V....Radojkovic D. (2009) Physical function is weakly associated with angiotens in-converting enzyme gene I/D polymorphism in elderly Japanese subjects. (PubMed id 19478476) 1 , 9 Yoshihara A....Miyazaki H. (2009) [Effect of angiotensin II type 1 receptor and angiote nsin-converting enzyme gene silencing on nuclear factor-kappaB activity in hepa tic stellate cells] (PubMed id 19304510) 1 , 9 Li X....Zhang Z.S. (2009) High dose Losartan and ACE gene polymorphism in IgA nephritis. (PubMed id 19319668) 1 , 9 Woo K.T....Wong K.S. (2009) Effects of imatinib mesylate on renin-angiotensin sys tem (RAS) activity during the clinical course of chronic myeloid leukaemia. (PubMed id 19761684) 1 , 9 Sayitoglu M....Ozbek U. (2009) Relationship between the angiotensin I-converting enzyme insertion/deletion (I/D) polymorphism and cardiovascular risk factors in healthy young Mexican women. (PubMed id 19371224) 1 , 9 Vallejo M....Vargas-AlarcA^n G. (2009) The relation of adiponectin and tumor necrosis factor alpha levels between endothelial nitric oxide synthase, angiotensin-converting enzyme, transforming growth factor beta, and tumor necrosis factor alpha gene polymorphism in adrenal incidentalomas. (PubMed id 19498318) 1 , 9 Harman E....Yilmaz C. (2009) The insertion/deletion polymorphism of the angiotensi n-converting enzyme gene is associated with progression, but not development, o f albuminuria in Iranian patients with type 2 diabetes. (PubMed id 19502259) 1 , 9 Nikzamir A....Reza J.Z. (2009) A synergistic association of ACE I/D and eNOS G894T g ene variants with the progression of immunoglobulin A nephropathy - a pilot stu dy. (PubMed id 19546528) 1 , 9 RodrA-guez-PAcrez J.C....Torres A. (2009) AGT and ACE genes influence classic mitral valve prolapse predisposition in Marfan patients. (PubMed id 17379330) 1 , 9 Fatini C....Pepe G. (2008) [Polymorphism of genes of the renin-angiotensin system ACE, AT1R, and AT2R in patients with pulmonary tuberculosis] (PubMed id 18488444) 1 , 9 Ogarkov O.B....Skvortsova R.G. (2008) ACE I/D polymorphism in Indian patients with hypertrophic cardiomyopathy and dilated cardiomyopathy. (PubMed id 18165925) 1 , 9 Rai T.S....Khullar M. (2008) Association of insertion/deletion polymorphism of angiotensin-converting enzyme gene with essential hypertension and type 2 diabetes mellitus in Malaysian subjects. (PubMed id 19126661) 1 , 9 Ramachandran V....Mohd Jas R. (2008) ACE gene polymorphism in Egyptian children with idiopathic nephrotic syndrome. (PubMed id 18792483) 1 , 9 Fahmy M.E....Essawi M.L. (2008) Association of angiotensin-converting enzyme and endothelial Nitric Oxide synthase gene polymorphisms with vascular disease in ESRD patients in a Chinese population. (PubMed id 18629615) 1 , 9 Tang F.Y....Xie X.W. (2008) IS THE PRESENCE OF RETINOPATHY OF PRACTICAL VALUE IN DEFINING CASES OF DIABETIC NEPHROPATHY IN GENETIC ASSOCIATION STUDIES? THE EXPERIENCE WITH THE ANGIOTENSIN-I CONVERTING ENZYME I/D POLYMORPHISM BASED ON 53 STUDIES COMPRISING 17,791 SUBJECTS. (PubMed id 18523141) 1 , 9 Ng D.P....Li L.X. (2008) [Effect of angiotensin converting enzyme genotype on endothelial function in healthy subjects] (PubMed id 18258525) 1 , 9 Tanriverdi H....Kilic M. (2008) [Influence of angiotensin converting enzyme gene insertion/deletion polymorphism and beta3-adrenergic receptor gene Trp64Arg polymorphism on fetal growth and neonatal insulin sensitivity] (PubMed id 19099777) 1 , 9 Cui Y.P....Ye H.M. (2008) Angiotensin-1 converting enzyme I/D gene polymorphism: scenario in Malaysia. (PubMed id 19058590) 1 , 9 Jayapalan J.J....Chan S.P. (2008) Different contributions of the angiotensin-converting enzyme C-domain and N-domain in subjects with the angiotensin-converting enzyme II and DD genotype. (PubMed id 18327080) 1 , 9 van Esch J.H....Jan Danser A.H. (2008) Relationships between blood pressure, polymorphism of angiotensin-converting enzyme (ACE), body composition and biochemical characteristics in elderly Slovaks. (PubMed id 18712159) 1 , 9 Sivakova D....Blazicek P. (2008) Influence of angiotensin I-converting enzyme polymorphism on development of post-transplant erythrocytosis in renal graft recipients. (PubMed id 18339134) 1 , 9 Kedzierska K....Ciechanowski K. (2008) The association of ACE gene D/I polymorphism with cardiovascular risk factors in a population from Rio de Janeiro. (PubMed id 18622495) 1 , 9 Cardoso R.L....Souza e Silva N.A. (2008) Angiotensin-converting enzyme polymorphisms and risk of spontaneous deep intracranial hemorrhage in Taiwan. (PubMed id 18754764) 1 , 9 Chen C.M....Lee-Chen G.J. (2008) Angiotensin-converting enzyme insertion/deletion polymorphism and the risk of ischemic stroke in a South Indian population. (PubMed id 18586276) 1 , 9 Munshi A....Jyothy A. (2008) Triple pharmacological blockade of the renin-angioten sin-aldosterone system in nondiabetic CKD: an open-label crossover randomized c ontrolled trial. (PubMed id 18423812) 7, 9 Tylicki L....Rutkowski B. (2008) The effects of angiotensin-converting enzyme gene polymorphism on the progression of immunoglobulin A nephropathy in Malaysian patients. (PubMed id 19037561) 1 , 9 Draman C.R....Shamsul A.S. (2008) Polymorphisms in two genes, IL-1B and ACE, are associated with erythropoietin resistance in Korean patients on maintenance hemodialysis. (PubMed id 18446054) 1 , 9 Jeong K.H....Moon J.Y. (2008) Angiotensinogen gene T235 variant: a marker for the development of persistent microalbuminuria in children and adolescents with type 1 diabetes mellitus. (PubMed id 18413222) 1 , 9 Gallego P.H....Choong C.S. (2008) Angiotensin-converting enzyme gene polymorphism is correlated to diabetic retinopathy: a meta-analysis. (PubMed id 18280446) 1 , 9 Wiwanitkit V. (2008) Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio. (PubMed id 17303661) 1 , 9 Wakahara S....Miyamori I. (2007) Lack of association between endothelial nitric oxide synthase gene polymorphisms, microalbuminuria and endothelial dysfunction in hypertensive men. (PubMed id 17563560) 1 , 9 Dell'Omo G....Pedrinelli R. (2007) Early sign of atherosclerosis in slow coronary flow and relationship with angiotensin-converting enzyme I/D polymorphism. (PubMed id 17285438) 1 , 9 Tanriverdi H....Kaftan A. (2007) Absence of an interaction between the angiotensin-converting enzyme insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensive patients: the Genetics of Hypertension-Associated Treatment (GenHAT) study. (PubMed id 17174637) 1 , 9 Maitland-van der Zee A.H....Eckfeldt J.H. (2007) Polymorphisms of the renin-angiotensin system genes predict progression of subclinical coronary atherosclerosis. (PubMed id 17327458) 1 , 9 Kretowski A....Rewers M. (2007) Polymorphism modulates symptomatic response to antiarrhythmic drug therapy in patients with lone atrial fibrillation. (PubMed id 17556195) 1 , 9 Darbar D....Roden D.M. (2007) High sodium intake strengthens the association of ACE I/D polymorphism with blood pressure in a community. (PubMed id 17586409) 1 , 9 Yamagishi K....Iso H. (2007) Evaluation of atrial and brain natriuretic polypeptides in association with angiotensin-converting enzyme gene polymorphism in Japanese non-diabetic hemodialysis patients. (PubMed id 17454955) 1 , 9 Nakao K....Doi T. (2007) Angiotensin-converting enzyme insertion/deletion (ACE I/D) and angiotensin II type 1 receptor (AT1R) gene polymorphism and its association with preeclampsia in Chinese women. (PubMed id 17710578) 1 , 9 Li H....Wang L. (2007) ACE gene polymorphism in peripheral vascular disease. (PubMed id 17611909) 1 , 9 Basar Y....Ozkok E. (2007) Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: a meta-analysis. (PubMed id 17171228) 1 , 9 Banerjee I....Ganesh S. (2007) [I/D polymorphism of angiotensin I converting enzyme gene and arterial hypertension in patients with type 2 diabetes mellitus] (PubMed id 17682668) 1 , 9 Moleda P....Adler G. (2007) Effect of angiotensin-converting enzyme insertion/deletion genotype on collagen type I synthesis and degradation in patients with atrial fibrillation and arterial hypertension. (PubMed id 17927479) 1 , 9 Tziakas D.N....Boudoulas H. (2007) Angiotensin-converting enzyme I/D and alpha-adducin Gly460Trp polymorphisms: from angiotensin-converting enzyme activity to cardiovascular outcome. (PubMed id 17452507) 1 , 9 Li Y....Staessen J.A. (2007) The role of angiotensin-converting enzyme gene insertion/deletion polymorphism for blood pressure regulation in areca nut chewers. (PubMed id 17585864) 1 , 9 Chung F.M....Lee Y.J. (2007) The relationship between angiotensin-converting enzyme (insertion/deletion) gene polymorphism and left ventricular remodeling in acute myocardial infarction. (PubMed id 17429286) 1 , 9 Ulgen M.S....Toprak N. (2007) Angiotensin-converting enzyme gene polymorphism and stroke in type 2 diabetic patients in Taiwan. (PubMed id 17537156) 1 , 9 Tseng C.H....Cheng J.C. (2007) Relationship of angiotensin-converting enzyme gene polymorphism with nephropathy associated with Type 2 diabetes mellitus in Asian Indians. (PubMed id 17616353) 1 , 9 Movva S....Hasan Q. (2007) Association between polymorphisms of ACE, B2AR, ANP and ENOS and cardiovascular diseases: a community-based study in the Matsu area. (PubMed id 17243909) 1 , 9 Hu C.J....Chang C.J. (2007) [Relationship between angiotensin converting enzyme gene and ischemic stroke] (PubMed id 17577432) 1 , 9 Li C.M....Qiu S.L. (2007) The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380. (PubMed id 17439247) 1 , 9 Corradi H.R....Acharya K.R. (2007) Association of ACE gene polymorphism with genetic susceptibility to systemic lupus erythematosus in a Chinese population: a family-based association study. (PubMed id 17937470) 1 , 9 Xu J....Ding C. (2007) Modification of the coronary artery disease risk associated with the presence of traditional risk factors by insertion/deletion polymorphism of the ACE gene. (PubMed id 18294050) 1 , 9 Niemiec P....Wita K. (2007) Renal function dependent association of AGTR1 polymorphism (A1166C) and electrocardiographic left-ventricular hypertrophy. (PubMed id 17903694) 1 , 9 Smilde T.D....Navis G. (2007) Study of candidate genes affecting the progression of renal disease in autosomal dominant polycystic kidney disease type 1. (PubMed id 17303584) 1 , 9 Tazon-Vega B....Torra R. (2007) ACE gene I/D polymorphism and the presence of renal failure or hypertension in autosomal dominant polycystic kidney disease (ADPKD). (PubMed id 17205958) 1 , 9 Gumprecht J....Grzeszczak W. (2007) Angiotensin I-converting enzyme insertion-related genotypes and allele are associated with higher susceptibility of endometriosis and leiomyoma. (PubMed id 17186537) 1 , 9 Hsieh Y.Y....Lin C.S. (2007) Effects of angiotensin-converting enzyme gene polymorphism and serum vitamin D levels on ambulatory blood pressure measurement and left ventricular mass in Turkish hypertensive population. (PubMed id 17625392) 1 , 9 Kulah E....Dursun A. (2007) Interaction of angiotensin-converting enzyme and apolipoprotein E gene polymorphisms in ischemic stroke involving large-vessel disease. (PubMed id 18027070) 1 , 9 Saidi S....Mahjoub T. (2007) Pharmacogenetic interactions of three candidate gene polymorphisms with ACE-inhibitors or beta-blockers and the risk of atherosclerosis. (PubMed id 17298481) 1 , 9 Schelleman H....Stricker B.H. (2007) Sequence variants of ACE, AGT, AT1R, and PAI-1 as genetic risk factors for vascular dementia. (PubMed id 16603315) 1 , 9 Kim Y....Lee C. (2006) [Meta-analysis of association of deletion allele of angiotensin-converting enzyme gene with coronary heart disease in China] (PubMed id 17166429) 1 , 9 Jiang X....Liao Y.H. (2006) A common variant in the ACE gene is associated with peripheral neuropathy in women with type 2 diabetes mellitus. (PubMed id 16949519) 1 , 9 Stephens J.W....Hurel S.J. (2006) ACE gene polymorphism in Turkish children with nephrotic syndrome. (PubMed id 16825089) 1 , 9 Celik U.S....Matyar S. (2006) ACE gene polymorphisms influence t-PA-induced brain vessel reopening following ischemic stroke. (PubMed id 16442232) 1 , 9 Fernandez-Cadenas I....Montaner J. (2006) Renal haemodynamics are not related to genotypes in offspring of parents with essential hypertension. (PubMed id 17083073) 1 , 9 Skov K....Mulvany M.J. (2006) Association analysis of genes in the renin-angiotensin system with subclinical cardiovascular disease in families with Type 2 diabetes mellitus: the Diabetes Heart Study. (PubMed id 16492203) 1 , 9 Burdon K.P....Bowden D.W. (2006) Insertion/deletion polymorphism of angiotensin converting enzyme gene in Kawasaki disease. (PubMed id 16614502) 1 , 9 Shim Y.H....Hong Y.M. (2006) Angiotensin converting enzyme has an inhibitory role in CGRP metabolism in human skin. (PubMed id 16406141) 1 , 9 Kramer H.H....Birklein F. (2006) The ACE-DD genotype is associated with endothelial dysfunction in postmenopausal women. (PubMed id 17003740) 1 , 9 Methot J....Poirier P. (2006) Restenosis after percutaneous coronary intervention is associated with the angiotensin-II type-1 receptor 1166A/C polymorphism but not with polymorphisms of angiotensin-converting enzyme, angiotensin-II receptor, angiotensinogen or heme oxygenase-1. (PubMed id 16609364) 1 , 9 Wijpkema J.S....Tio R.A. (2006) Angiotensin-I-converting enzyme (ACE) insertion/deletion polymorphism in Mexican patients with coronary artery disease. Association with the disease but not with lipid levels. (PubMed id 16764852) 1 , 9 Vargas-Alarcon G....Posadas-Romero C. (2006) [The incidence of some angiotensin-1 converting enzyme gene alleles in patients with coronary heart disease] (PubMed id 16512390) 1 , 9 Istrati V.F....Kalin G.V. (2006) [The relationship between ACE I/D polymorphism and HDL cholesterol] (PubMed id 17168204) 1 , 9 You C.H....Kim J.Y. (2006) ACE gene insertion/deletion polymorphism modulates capillary permeability in hypertension. (PubMed id 16889537) 1 , 9 Dell'omo G....Pedrinelli R. (2006) Hydrochlorothiazide efficacy and polymorphisms in ACE, ADD1 and GNB3 in healthy, male volunteers. (PubMed id 16450155) 1 , 9 Vormfelde S.V....Brockmoller J. (2006) Insertion/Deletion Polymorphism on ACE Gene is Associated with Endothelial Dysfunction in Young Patients with Hypertension. (PubMed id 16981142) 1 , 9 Penesova A....Krizanova O. (2006) Angiotensin I-converting enzyme gene polymorphism modifies the smoking-cancer association: the Hisayama Study. (PubMed id 16679861) 1 , 9 Arima H....Iida M. (2006) Angiotensin-converting enzyme gene insertion/deletion polymorphism in Korean patients with systemic sclerosis. (PubMed id 16614523) 1 , 9 Joung C.I....Yoo D.H. (2006) Perindopril. (PubMed id 16370923) 7, 9 Alfakih K. and Hall A.S. (2006) Angiotensin converting enzyme gene polymorphisms do not predict the course of idiopathic nephrotic syndrome in Swiss children. (PubMed id 17199794) 1 , 9 Sasse B....Neuhaus T.J. (2006) Angiotensin-converting enzyme gene polymorphism is correlated to the progression of disease in patients with IgA nephropathy: a meta-analysis. (PubMed id 17162429) 1 , 9 Wiwanitkit V. (2006) Angiotensin-converting enzyme gene polymorphism in children with idiopathic nephrotic syndrome. (PubMed id 16645262) 1 , 9 Tsai I.J....Hsieh F.J. (2006) The effect of ACE gene polymorphisms on Doppler blood flow parameters of carotid and brachial arteries in patients with myocardial infarction. (PubMed id 17235107) 1 , 9 Bilici A....Alan B. (2006) Association between angiotensin-converting enzyme gene polymorphisms and QT duration in a multiethnic population in Hawaii. (PubMed id 16769256) 1 , 9 Grandinetti A....Low P.A. (2006) ACE gene dosage modulates pressure-induced cardiac hypertrophy in mice and men. (PubMed id 16926271) 1 , 9 Silva G.J....Krieger J.E. (2006) Effects of angiotensin II type 1 receptor gene polymorphisms on insulin resistance in a Japanese general population: the Tanno-Sobetsu study. (PubMed id 17378368) 1 , 9 Akasaka H....Ogihara T. (2006) Genetic susceptibility to atrial fibrillation in patients with congestive heart failure. (PubMed id 16818212) 1 , 9 Bedi M....Schwartzman D. (2006) Angiotensin converting enzyme insertion/deletion polymorphism does not influence postcardiac transplantation hypertension onset or progression. (PubMed id 15797740) 1 , 9 Fildes J.E....Yonan N. (2005) Signaling via the angiotensin-converting enzyme enhances the expression of cyclooxygenase-2 in endothelial cells. (PubMed id 15569856) 1 , 9 Kohlstedt K....Fleming I. (2005) Effects of angiotensin-converting enzyme polymorphism on aortic elastic parameters in athletes. (PubMed id 16088128) 1 , 9 Tanriverdi H....Kilic M. (2005) Angiotensin-converting enzyme genotype is not associated with exercise capacity or the training effect of cardiac rehabilitation in patients after acute myocardial infarction. (PubMed id 16247204) 1 , 9 Iwanaga Y....Goto Y. (2005) [Angiotensin I-converting enzyme in cerebrospinal fluid and neurosarcoidosis] (PubMed id 16230281) 1 , 9 Baudin B....Vaubourdolle M. (2005) Angiotensin-converting enzyme (ACE) haplotypes and cyclosporine A (CsA) response: a model of the complex relationship between ACE quantitative trait locus and pathological phenotypes. (PubMed id 16002416) 1 , 9 Catarsi P....Ghiggeri G.M. (2005) [The influence of I/D polymorphism of the angiotensin I converting enzyme (ACE) gene and 4G/5G polymorphism of plasminogen activator inhibitor (PAI-1) gene promoter on the haemostatic system in patients with essential hypertension and dyslipidemia] (PubMed id 16496609) 1 , 9 Nowakowska A. (2005) Frequency of angiotensin-converting enzyme gene polymorphism in Turkish type 2 diabetic patients. (PubMed id 16178979) 1 , 9 Degirmenci I....Demirustu C. (2005) Influence of angiotensin-converting enzyme polymorphism gene, IGF-1, and other factors in the response rate of hematocrit to enalapril treatment in patients with posttransplant erythrocytosis. (PubMed id 15848608) 1 , 9 Jimeno L....Minguela A. (2005) ACE gene polymorphism in children with nephrotic syndrome in the Indonesian population. (PubMed id 16421456) 1 , 9 Sasongko T.H....Nishio H. (2005) Low renin-angiotensin system activity gene polymorphism and dysplasia associated with posterior urethral valves. (PubMed id 16006956) 1 , 9 Peruzzi L....Coppo R. (2005) Gene polymorphisms of angiotensin II type 1 receptor and angiotensin-converting enzyme in two ethnic groups living in Zhejiang Province, China. (PubMed id 16525943) 1 , 9 Yan C....Feng W. (2005) Lack of association between common polymorphisms in genes of the renin-angiotensin system and mortality after myocardial infarction. (PubMed id 15785027) 1 , 9 Andrikopoulos G.K....Mattu R. (2005) Glyceryl trinitrate-induced angiotensin-converting enzyme (ACE) inhibition in healthy volunteers is dependent on ACE genotype. (PubMed id 16462911) 1 , 9 Persson K....Ahlner J. (2005) Renin-angiotensin polymorphisms and QTc interval prolongation in end-stage renal disease. (PubMed id 16105049) 1 , 9 Raizada V....Spalding C.T. (2005) [Do left ventricular mass, diameters and long-axis systolic function differ according to angiotensin converting enzyme genotypes?] (PubMed id 16140645) 1 , 9 Dursunoglu D....Kilic M. (2005) Influence of angiotensin-converting enzyme I/D gene polymorphism on the right ventricular myocardial performance index in patients with a first acute anterior myocardial infarction. (PubMed id 15671615) 1 , 9 Ozturk O....Toprak N. (2005) The relation between obesity, abdominal fat deposit and the angiotensin-converting enzyme gene I/D polymorphism and its association with coronary heart disease. (PubMed id 15520830) 1 , 9 Riera-Fortuny C....Hernandez-Mijares A. (2005) Novel approach of molecular genetic understanding of iridology: relationship between iris constitution and angiotensin converting enzyme gene polymorphism. (PubMed id 16047566) 1 , 9 Um J.Y....Kim H.M. (2005) [I/D-polymorphism of ACE gene, morphofunctional heart condition and blood pressure 24-h profile in young men with arterial hypertension] (PubMed id 16281482) 1 , 9 Bagmet A.D. and Shestopal N.S. (2005) Polymorphisms of the renin-angiotensin system genes in Brazilian patients with lupus nephropathy. (PubMed id 15934435) 1 , 9 Sprovieri S.R. and Sens Y.A. (2005) [The influence of gene polymorphism of the angiotensin-converting enzyme in donor and recipient on the function of renal graft] (PubMed id 16496610) 1 , 9 Kabat-Koperska J. (2005) Polymorphisms of the renin-angiotensin system and the severity of fibrosis in chronic hepatitis C virus infection. (PubMed id 16108768) 1 , 9 Forrest E.H....Mills P.R. (2005) Angiotensin-converting enzyme i/d polymorphism in patients with malignant hypertension. (PubMed id 15655381) 1 , 9 Espinel E....Bachs A.G. (2005) ACE gene insertion/deletion polymorphism in childhood idiopathic nephrotic syndrome. (PubMed id 16208534) 1 , 9 Serdaroglu E....Bak M. (2005) Over-expression of angiotensin converting enzyme-1 augments cardiac hypertrophy in transgenic rats. (PubMed id 15128700) 1 , 9 Tian X.L....Paul M. (2004) ACE I/D gene polymorphism in primary FSGS and steroid-sensitive nephrotic syndrome. (PubMed id 14986085) 1 , 9 Oktem F....Ispir T. (2004) [Study on relationship between the polymorphism of angiotensin converting enzyme gene and blood stasis syndrome in patients with coronary heart disease] (PubMed id 15495818) 1 , 9 Mao Y.L....Hu Z. (2004) Family-based associations between the angiotensin- converting enzyme insertion/deletion polymorphism and multiple cardiovascular risk factors in Chinese. (PubMed id 15076153) 1 , 9 Wang J.G....Zhu D.L. (2004) Carotid remodeling of hypertensive subjects and polymorphism of the angiotensin-converting enzyme gene. (PubMed id 14733772) 1 , 9 Li S.J....Zhou S.M. (2004) Polymorphism of the ACE gene is associated with extent and severity of coronary disease. (PubMed id 15732661) 1 , 9 Mendonca I....dos Reis R.P. (2004) Polymorphism of renin-angiotensin system genes in IgA nephropathy. (PubMed id 15504143) 1 , 9 Woo K.T....Wong K.S. (2004) Genetic polymorphisms of angiotensin system genes in congenital diaphragmatic hernia associated with persistent pulmonary hypertension. (PubMed id 15017542) 1 , 9 Solari V. and Puri P. (2004) Renin angiotensin aldosterone system and ACE I/D gene polymorphism in high-altitude pulmonary edema. (PubMed id 15558999) 1 , 9 Kumar R....Gupta V. (2004) Renin-angiotensin system gene polymorphisms: its impact on IgAN and its progression to end-stage renal failure among Chinese in Singapore. (PubMed id 15153745) 1 , 9 Lau Y.K....Wong K.S. (2004) Angiotensin converting enzyme genotype and chronic allograft nephropathy in protocol biopsies. (PubMed id 15284309) 1 , 9 Hueso M....Seron D. (2004) Angiotensin-converting enzyme gene polymorphism and risk of myocardial infarction in Colombia. (PubMed id 15277998) 1 , 9 Bautista L.E....Arenas I.A. (2004) GNB3 gene C825T and ACE gene I/D polymorphisms in essential hypertension in a Kazakh genetic isolate. (PubMed id 15042113) 1 , 9 Wang X....Wen H. (2004) Progression of left ventricular hypertrophy and the angiotensin-converting enzyme gene polymorphism in hypertrophic cardiomyopathy. (PubMed id 15314809) 1 , 9 Doolan G....Semsarian C. (2004) A study of gene--environment interaction on the gene for angiotensin converting enzyme: a combined functional and population based approach. (PubMed id 14757856) 1 , 9 Sayed-Tabatabaei F.A....van Duijn C.M. (2004) Pharmacological and clinical profile of moexipril: a concise review. (PubMed id 15286086) 7, 9 Chrysant S.G. and Chrysant G.S. (2004) Renin-angiotensin system and associated gene polymorphisms in myocardial infarction in young South African Indians. (PubMed id 14997233) 1 , 9 Ranjith N....Naidoo D.P. (2004) Interaction and relationship between angiotensin converting enzyme gene and environmental factors predisposing to essential hypertension in Mongolian population of China. (PubMed id 15386943) 1 , 9 Xu Q....Qiu C.C. (2004) The functional angiotensin converting enzyme gene I/D polymorphism does not alter susceptibility to chronic pancreatitis. (PubMed id 15536282) 1 , 9 Oruc N....Whitcomb D.C. (2004) The role of angiotensin-converting enzyme and apolipoprotein-E gene polymorphisms on lipid compositions in newborn infants with intrauterine growth restriction. (PubMed id 15223114) 1 , 9 Akisu M....Kultursay N. (2004) The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin-converting enzyme inhibitor. (PubMed id 15226090) 1 , 9 Jiang S....Xu X. (2004) ACE genotype and cognitive decline in an African-Caribbean population. (PubMed id 15465635) 1 , 9 Stewart R....Mann A. (2004) Possible synergic effect of angiotensin-I converting enzyme gene insertion/deletion polymorphism and angiotensin-II type-1 receptor 1166A/C gene polymorphism on ischemic heart disease in patients with Kawasaki disease. (PubMed id 15295089) 1 , 9 Fukazawa R....Ogawa S. (2004) Renin-angiotensin system polymorphisms in Taiwanese primary vesicoureteral reflux. (PubMed id 15045574) 1 , 9 Liu K.P....Lee-Chen G.J. (2004) Acute effects of nifedipine administration in pulmonary haemodynamics and oxygen delivery during exercise in patients with chronic obstructive pulmonary disease: implication of the angiotensin-converting enzyme gene polymorphisms. (PubMed id 15233837) 1 , 9 Kanazawa H....Yoshikawa J. (2004) Angiotensinogen 235T allele 'dosage' is associated with blood pressure phenotypes. (PubMed id 12511525) 1 , 9 Pereira A.C....Krieger J.E. (2003) Polymorphism of angiotensin-converting enzyme gene and BMI in obese Korean women. (PubMed id 12559614) 1 , 9 Um J.Y....Kim H.M. (2003) Angiotensin-converting enzyme-gene polymorphism is associated with collagen I synthesis and QT dispersion in essential hypertension. (PubMed id 12714874) 1 , 9 Takahashi T....Takata M. (2003) Renin-angiotensin system gene polymorphisms: assessment of the risk of coronary heart disease. (PubMed id 14502296) 1 , 9 Buraczynska M....Ksiazek A. (2003) Angiotensin-converting enzyme gene (ACE) insertion/deletion polymorphism in Mexican populations. (PubMed id 15018037) 1 , 9 Vargas-Alarcon G....Granados J. (2003) Effects of hormone replacement therapy on serum angiotensin-converting enzyme activity and plasma bradykinin in postmenopausal women according to angiotensin-converting enzyme-genotype. (PubMed id 12661913) 1 , 9 Sumino H....Kurabayashi M. (2003) Interaction between angiotensin-converting enzyme genotype and glycaemic control influences lipoprotein levels in type 2 diabetes mellitus. (PubMed id 12658909) 1 , 9 Tkac I....Kalina I. (2003) No effect of angiotensin-converting enzyme gene polymorphism on disease progression and left ventricular hypertrophy in autosomal dominant polycystic kidney disease. (PubMed id 14600431) 1 , 9 Ecder T....Schrier R.W. (2003) Association of high-altitude systemic hypertension with the deletion allele-of the angiotensin-converting enzyme (ACE) gene. (PubMed id 12743791) 1 , 9 Kumar R....Brahamchari S.K. (2003) Relationship between ACE gene polymorphism and ischemic chronic heart failure in Turkish population. (PubMed id 12911874) 1 , 9 Akbulut T....Yesilcimen K. (2003) Interaction between angiotensin-converting enzyme and catechol-O-methyltransferase genotypes in schizophrenics with poor response to conventional neuroleptics. (PubMed id 12729939) 1 , 9 Illi A....Leinonen E. (2003) Angiotensin-converting enzyme genotype modulates pulmonary function and exercise capacity in treated patients with congestive stable heart failure. (PubMed id 12356632) 1 , 9 Abraham M.R....Johnson B.D. (2002) Angiotensin-converting enzyme insertion/deletion polymorphism does not influence the restenosis rate after coronary stent implantation. (PubMed id 11893827) 1 , 9 Ferrari M....Figulla H.R. (2002) Gene polymorphisms of the renin-angiotensin-aldosterone system and essential arterial hypertension in childhood. (PubMed id 12597535) 1 , 9 Petrovic D....Peterlin B. (2002) ACE gene polymorphism and renal scar in children with acute pyelonephritis. (PubMed id 12172760) 1 , 9 Cho S.J. and Lee S.J. (2002) The role of ACE gene polymorphism in rapidity of progression of focal segmental glomerulosclerosis. (PubMed id 12571380) 1 , 9 Dixit M....Glicklich D. (2002) Angiotensin-converting enzyme gene insertion/deletion polymorphism in Polish patients with myocardial infarction. (PubMed id 12898814) 1 , 9 Sobstyl J....Hanzlik J. (2002) [Influence of ACE inhibitor spirapril on left ventricular hypertrophy] (PubMed id 12613273) 7, 9 Arend U....Schmidt J. (2002) Relation of Apo E and ACE genes to cognitive performance in chronic alcoholic patients. (PubMed id 12006218) 1 , 9 Bartres-Faz D....Junque C. (2002) [Association of insertion/deletion polymorphism in angiotensin-converting enzyme gene with hypertensive type 2 diabetes mellitus] (PubMed id 12297438) 1 , 9 Zhou L....Gao F. (2002) Angiotensin-converting enzyme genotype and outcome in pediatric IgA nephropathy. (PubMed id 12172761) 1 , 9 Santos N.M....Wyatt R.J. (2002) Polymorphism of the angiotensin converting enzyme gene and blood pressure in a Japanese general population (the Shigaraki Study). (PubMed id 12484507) 1 , 9 Tamaki S....Ueshima H. (2002) Genetic polymorphisms of renin-angiotensin system and progression of interstitial nephritis. (PubMed id 12898858) 1 , 9 Buraczynska M....Ksiazek A. (2002) The effect of angiotensin converting enzyme gene polymorphism on chronic allograft dysfunction in living donor renal transplant recipients. (PubMed id 12010139) 1 , 9 Yildiz A....Erginel-Unaltuna N. (2002) Association of the ACE gene I/D polymorphism with insulin sensitivity depends on the presence of additional macroangiopathic risk factors. (PubMed id 11755945) 4, 9 Thamer C....Stumvoll M. (2002) Both alleles of the M235T polymorphism of the angiotensinogen gene can be a risk factor for myocardial infarction. (PubMed id 11531970) 1 , 9 Fernandez-Arcas N....Reyes-Engel A. (2001) Significance of ACE genotypes and medical treatments in childhood focal glomerulosclerosis. (PubMed id 11474225) 1 , 9 Hori C....Mayumi M. (2001) [Polymorphism of the angiotensin-converting enzyme gene in patients with coronary heart disease from Moscow population] (PubMed id 11421129) 1 , 9 Shadrina M.I....Limborskaia S.A. (2001) Increased risk for ischaemic events is related to combined RAS polymorphism. (PubMed id 11250978) 1 , 9 van Geel P.P....van Gilst W.H. (2001) Loss of renal function following bone marrow transplantation: an analysis of angiotensin converting enzyme D/I polymorphism and other clinical risk factors. (PubMed id 11313676) 1 , 9 Juckett M.B....Klein J. (2001) Angiotensin converting enzyme gene polymorphism predicts blood pressure response to angiotensin II receptor type 1 antagonist treatment in hypertensive patients. (PubMed id 11593098) 1 , 9 Kurland L....Lind L. (2001) Association of the DD genotype and development of Japanese type 2 diabetic nephropathy. (PubMed id 11770799) 1 , 9 Gohda T....Tomino Y. (2001) Relationship between angiotensin-converting enzyme gene polymorphism and insulin resistance in never-treated hypertensive patients. (PubMed id 11231997) 1 , 9 Perticone F....Mattioli P.L. (2001) Interaction between apolipoprotein-E and angiotensin-converting enzyme genotype in Alzheimer's disease. (PubMed id 11501342) 1 , 9 Isbir T....Eker E. (2001) Prognostic value of angiotensin-I converting enzyme I/D polymorphism for nephropathy in type 1 diabetes mellitus: a prospective study. (PubMed id 11181802) 1 , 9 Hadjadj S....Marre M. (2001) Angiotensin converting enzyme in patients with sleep apnoea syndrome: plasma activity and gene polymorphisms. (PubMed id 11401071) 1 , 9 Barcelo A....Agusti A.G. (2001) ACE genotype and endothelium-dependent vasodilation of conduit arteries and forearm microcirculation in humans. (PubMed id 11498459) 1 , 9 Arcaro G....Bonadonna R.C. (2001) Angiotensin-converting enzyme gene polymorphism, lipids, and apolipoproteins in menopausal women on hormone replacement therapy. (PubMed id 12398019) 1 , 9 Cubrilo-Turek M....Durakovic Z. (2001) Polymorphism of the angiotensin-converting enzyme gene in patients with cerebral infarction in Koreans. (PubMed id 11859923) 1 , 9 Um J.Y....Kim J.J. (2001) The angiotensin I converting enzyme gene as a susceptibility factor for dementia. (PubMed id 11402126) 1 , 9 Richard F....Helbecque N. (2001) Angiotensin converting enzyme gene insertion/deletion polymorphism in idiopathic nephrotic syndrome in Kuwaiti Arab children. (PubMed id 11487079) 1 , 9 Al-Eisa A....Srivastva B.S. (2001) Angiotensin-converting enzyme gene polymorphism in a cohort of coronary angiography patients. (PubMed id 11257269) 1 , 9 Eichner J.E....Schechter E. (2001) The ACE gene I/D polymorphism, but not the angiotensin II type I receptor gene A1166C polymorphism is associated with isolated systolic hypertension. (PubMed id 11550114) 4, 9 Davis D....Johnson A. (2001) Low potentiality of angiotensin-converting enzyme gene insertion/deletion polymorphism as a useful predictive marker for carotid atherogenesis in a large general population of a Japanese city: the Suita study. (PubMed id 11387483) 1 , 9 Mannami T....Ogata J. (2001) Ace D/I polymorphism and incidence of post-PTCA restenosis: a prospective, angiography-based evaluation. (PubMed id 11244007) 1 , 9 Zee R.Y....Fernandez-Cruz A. (2001) Is there a role of angiotensin-converting enzyme gene polymorphism in the failure of arteriovenous femoral shunts for hemodialysis? (PubMed id 11525534) 1 , 9 Isbir C.S....Cobanoglu A. (2001) ACE gene polymorphism and IgA nephropathy: an ethnically homogeneous study and a meta-analysis. (PubMed id 11473656) 1 , 9 Schena F.P....Gesualdo L. (2001) Ace gene I/D polymorphism and sarcoidosis pulmonary disease severity. (PubMed id 11463587) 1 , 9 McGrath D.S....Dolek V. (2001) The DD genotype of angiotensin converting enzyme polymorphism is a risk factor for coronary artery disease and coronary stent restenosis in Japanese patients. (PubMed id 11665795) 1 , 9 Taniguchi I....Mochizuki S. (2001) The deletion polymorphism of the angiotensin-converting enzyme is associated with nephroangiosclerosis. (PubMed id 10821348) 4, 9 Mallamaci F....Zucchelli P. (2000) Renin-angiotensin system polymorphisms and coronary events in familial hypercholesterolemia. (PubMed id 11082147) 1 , 9 Wierzbicki A.S....Crook M.A. (2000) [The relationship between angiotensin converting enzyme gene polymorphism and risk factors for coronary heart disease] (PubMed id 11860787) 1 , 9 Shan J....Fu G. (2000) Lack of association between polymorphisms of eight candidate genes and idiopathic dilated cardiomyopathy: the CARDIGENE study. (PubMed id 10636255) 4, 9 Tiret L....Komajda M. (2000) Relation between the insertion/deletion polymorphism of the angiotensin I converting enzyme gene and restenosis after coronary stenting. (PubMed id 11155292) 1 , 9 Gurlek A....Oral D. (2000) [Polymorphism of genes coding for angiotensin I converting enzyme and methylenetetrahydrofolate reductase in patients with ischemic heart disease] (PubMed id 11712321) 1 , 9 Goracy I. (2000) Cardiovascular risk factors and Alzheimer's disease: a genetic association study in a population aged 85 or over. (PubMed id 11018310) 4, 9 Myllykangas L....Perez-Tur J. (2000) Deletion polymorphism of angiotensin-converting enzyme gene is associated with postprandial hyperglycaemia in individuals undergoing general check-up. (PubMed id 10874503) 4, 9 Ohishi M....Ogihara T. (2000) Lack of association of ACE/angiotensinogen genotype with renal function in autosomal dominant polycystic kidney disease. (PubMed id 11142763) 1 , 9 Saggar-Malik A.K....Jeffery S. (2000) Polymorphism of angiotensin-converting enzyme gene and genetic susceptibility to asthma with familial aggregation. (PubMed id 12899394) 1 , 9 Gao J....Bai Y. (2000) ACE DD genotype is more susceptible than ACE II and ID genotypes to the antiproteinuric effect of ACE inhibitors in patients with proteinuric non-insulin-dependent diabetes mellitus. (PubMed id 11007831) 4, 9 Ha S.K....Suk Han D. (2000) Association between angiotensin-converting enzyme and Alzheimer disease. (PubMed id 10681079) 4, 9 Farrer L.A....Rogaev E.I. (2000) Lack of association between deletion polymorphism of the ACE gene and ischemic vascular diseases in a Chinese population in Taiwan. (PubMed id 10575803) 4, 9 Lin J.J....Yeh Y.H. (1999) The angiotensin-converting enzyme DD gene is associated with poor prognosis in Finnish sarcoidosis patients. (PubMed id 10362030) 4, 9 Pietinalho A....Selroos O. (1999) The DD genotype of the angiotensin converting enzyme gene is negatively associated with right ventricular hypertrophy in male patients with chronic obstructive pulmonary disease. (PubMed id 10351920) 4, 9 van Suylen R.J....Daemen M.J. (1999) Association of angiotensin-converting enzyme gene polymorphism with lipid profiles in children and adolescents with insulin-dependent diabetes mellitus. (PubMed id 10474023) 4, 9 Kobayashi K....Nakazawa S. (1999) [Polymorphism of angiotensin-converting enzyme gene and susceptibility to asthma with familial aggregation] (PubMed id 11776522) 1 , 9 Gao J....Xiao Y. (1999) Association between angiotensin-converting enzyme gene polymorphism and coronary artery disease. (PubMed id 10794598) 4, 9 Isbir T....Isbir C.S. (1999) DD angiotensin-converting enzyme gene polymorphism is associated with endothelial dysfunction in normal humans. (PubMed id 10334805) 4, 9 Butler R....Struthers A.D. (1999) Angiotensin-converting enzyme inhibition and AT1 receptor blockade modify the pressure-natriuresis relationship by additive mechanisms in rats with human renin and angiotensinogen genes. (PubMed id 10446934) 7, 9 Mervaala E....Luft F.C. (1999) Gene polymorphisms of the renin-angiotensin system in essential hypertension. (PubMed id 11593574) 4, 9 Liu Y....Cao J. (1999) ACE gene polymorphism in childhood IgA nephropathy: association with clinicopathologic findings. (PubMed id 9590186) 4, 9 Tanaka R....Yoshikawa N. (1998) Angiotensin-converting enzyme gene polymorphism is not associated with coronary atherosclerosis and myocardial infarction in a sample of Italian patients. (PubMed id 9693941) 4, 9 Arca M....Ricci G. (1998) [Association between myocardial infarction and angiotensin converting enzyme gene polymorphism in young patients] (PubMed id 9611729) 4, 9 Espinosa J.S....de Teresa E. (1998) Angiotensin-converting enzyme gene polymorphism is associated with coronary heart disease in non-insulin-dependent diabetic patients evaluated for 9 years. (PubMed id 9781631) 4, 9 Huang X.H....Lehtimaki T. (1998) Association between angiotensin II receptor gene polymorphism and serum angiotensin converting enzyme (SACE) activity in patients with sarcoidosis. (PubMed id 9713444) 4, 9 Takemoto Y....Ueda E. (1998) Association of genetic polymorphisms in the ACE, ApoE, and TGF beta genes with early onset ischemic heart disease. (PubMed id 9825196) 4, 9 Biggart S....Mayne L. (1998) Polymorphisms of angiotensin converting enzyme and plasminogen activator inhibitor-1 genes in diabetes and macroangiopathy1. (PubMed id 9844142) 4, 9 Kimura H....Arakawa M. (1998) [Association analysis of polymorphism in angiotensin-converting enzyme gene in ischemic stroke] (PubMed id 9677696) 4, 9 Moliaka I.u.K....Rogaev E.N. (1998) [Deletion polymorphism in the angiotensin converting enzyme gene associated with essential hypertension in Hans Chinese population] (PubMed id 11367719) 4, 9 Qiu C....Song C. (1998) ACE I/D gene polymorphism: presence of the ACE D allele increases the risk of coronary artery disease in younger individuals. (PubMed id 9699903) 1 , 9 Gardemann A....Haberbosch W. (1998) Meta-analysis of association of insertion/deletion polymorphism of angiotensin I-converting enzyme gene with diabetic nephropathy and retinopathy. (PubMed id 9498629) 4, 9 Fujisawa T....Ogihara T. (1998) Relationship of the angiotensin-converting enzyme gene polymorphism to glucose intolerance, insulin resistance, and hypertension in NIDDM. (PubMed id 9544854) 4, 9 Huang X.H....Lehtimaki T. (1998) The insertion allele at the angiotensin I-converting enzyme gene locus is associated with insulin resistance. (PubMed id 9109842) 4, 9 Chiu K.C. and McCarthy J.E. (1997) Lack of association between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and vasospastic angina. (PubMed id 9377825) 4, 9 Kuroki S....Shimada K. (1997) Is ACE gene polymorphism associated with lone atrial fibrillation? (PubMed id 9462412) 4, 9 Yamashita T....Murakawa Y. (1997) Association of the angiotensin I converting enzyme gene deletion polymorphism with early onset of ESRF in PKD1 adult polycystic kidney disease. (PubMed id 9291178) 4, 9 Baboolal K....Williams J.D. (1997) Lack of association of angiotensin converting enzyme gene polymorphism or serum enzyme activity with coronary artery disease in Japanese subjects. (PubMed id 9443774) 4, 9 Fujimura T....Yamada Y. (1997) [Angiotensin-converting enzyme gene polymorphism and the clinical pathological features and progression in lupus nephritis] (PubMed id 10436947) 4, 9 Guan T....Chen Z. (1997) Association of a deletion polymorphism of the angiotensin-converting enzyme gene with left-ventricular hypertrophy in Japanese women with essential hypertension; multicenter study of 1,919 subjects. (PubMed id 9197423) 4, 9 Kimura M....Yamada Y. (1997) Association of angiotensin converting enzyme and angiotensin II type 1 receptor genotypes with left ventricular function and mass in patients with angiographically normal coronary arteries. (PubMed id 9227291) 4, 9 Hamon M....Amouyel P. (1997) Lack of association between angiotensin-converting enzyme gene polymorphism and coronary heart disease in a Chinese population. (PubMed id 9201110) 4, 9 Chiang F.T....Tseng Y.Z. (1997) Angiotensin-converting enzyme gene polymorphism in non-insulin dependent diabetes mellitus and its relationship with diabetic nephropathy. (PubMed id 9264004) 4, 9 Jeffers B.W....Schrier R.W. (1997) Deletion polymorphism in angiotensin converting enzyme gene associated with carotid wall thickening in a healthy male population. (PubMed id 8773433) 4, 9 Pujia A....Gnasso A. (1996) Deletion polymorphism of the angiotensin-converting enzyme gene is independently associated with left ventricular mass and geometric remodeling in systemic hypertension. (PubMed id 8677872) 4, 9 Gharavi A.G....Phillips R.A. (1996) [Absence of an association of the D allele of the ACE gene with arterial pressure in mild-moderate essential arterial hypertension] (PubMed id 8983828) 4, 9 Celentano A....de Divitiis O. (1996) Aortic atherosclerosis in diabetes mellitus is associated with an insertion/deletion polymorphism in the angiotensin I-converting enzyme gene. No relation between the polymorphism and aortic collagen content. (PubMed id 8781765) 4, 9 Rasmussen L.M. and Ledet T. (1996) Angiotensin I converting enzyme gene polymorphism in non-insulin dependent diabetes mellitus. (PubMed id 8840299) 4, 9 Yoshida H....Sakai O. (1996) Association between angiotensin-converting-enzyme gene polymorphism and failure of renoprotective therapy. (PubMed id 8538349) 4, 9 van Essen G.G....de Jong P.E. (1996) Association analyses of the polymorphisms of angiotensin-converting enzyme and angiotensinogen genes with diabetic nephropathy in Japanese non-insulin-dependent diabetics. (PubMed id 8596493) 4, 9 Ohno T....Tomono S. (1996) Lack of association of angiotensin-converting enzyme (ACE). Gene insertion/deletion polymorphism with CAD in two Asian populations. (PubMed id 8946109) 4, 9 Saha N....Basair J. (1996) Angiotensin-converting enzyme gene polymorphism is associated with carotid arterial wall thickness in non-insulin-dependent diabetic patients. (PubMed id 8772691) 4, 9 Hosoi M....Morii H. (1996) A deletion polymorphism in the angiotensin converting enzyme gene is not associated with coronary heart disease in an Austrian population. (PubMed id 7772074) 4, 9 Friedl W....Sandhofer F. (1995) The insertion allele of the ACE gene I/D polymorphism. A candidate gene for insulin resistance? (PubMed id 8521557) 4, 9 Panahloo A....Yudkin J.S. (1995) Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with serum ACE concentration and increased risk for CAD in the Japanese. (PubMed id 7955173) 4, 9 Nakai K....Hiramori K. (1994) Association between ACE-D/D polymorphism and hypertension in type II diabetic subjects. (PubMed id 7807499) 4, 9 Pujia A....Mattioli P.L. (1994) Renal effects of angiotensin II in normotensive subje cts on short-term cilazapril treatment. (PubMed id 1382161) 7, 9 Hannedouche T....GrA1nfeld J.P. (1992) The two homologous domains of human angiotensin I-converting enzyme interact differently with competitive inhibitors. (PubMed id 1320019) 1 , 9 Wei L....Corvol P. (1992) Association between angiotensin-converting enzyme gene polymorphism and diabetic retinopathy in the Chinese population. (PubMed id 22249557) 1 Lu Y....Huang Z. (2012) Increased frequency of the DI genotype of the angioten sin-I converting enzyme and association of the II genotype with insulin resistan ce in polycystic ovary syndrome. (PubMed id 22223701) 1 Koika V....Panidis D. (2012) Genetic influences on right ventricular systolic press ure (RVSP) in chronic obstructive pulmonary disease (COPD). (PubMed id 22695028) 1 Shaw J.G....Yang I.A. (2012) Elevated serum angiotensin converting enzyme levels as a reflection of bone marrow renin-angiotensin system activation in multiple mye loma. (PubMed id 22345095) 1 Albayrak M....Celik T. (2012) Angiotensin-converting enzyme (ACE) serum levels and g ene polymorphism in Egyptian patients with systemic lupus erythematosus. (PubMed id 21976404) 1 Abbas D....Gamil M. (2012) Phosphorylation of amyloid-b peptide at serine 8 atten uates its clearance via insulin-degrading and angiotensin-converting enzymes. (PubMed id 22267728) 1 Kumar S....Walter J. (2012) LPS activates ADAM9 dependent shedding of ACE from end othelial cells. (PubMed id 22480688) 1 English W.R....Murphy G. (2012) The association of angiotensin-converting enzyme gene insertion/deletion polymorphisms with OSA: a meta-analysis. (PubMed id 22183487) 1 Lee P....Riha R.L. (2012) A direct interaction between DCP1 and XRN1 couples mRN A decapping to 5' exonucleolytic degradation. (PubMed id 23142987) 1 Braun J.E....Izaurralde E. (2012) Gene polymorphism in angiotensin-I-converting enzyme a nd physical activity among normotensive Chinese. (PubMed id 22693240) 1 Wong W.P....Koh W.P. (2012) Angiotensin-converting enzyme (ACE) gene insertion/del etion polymorphism and ACE inhibitor-related cough: a meta-analysis. (PubMed id 22723835) 1 Li Y.F....Yang X.C. (2012) Epigenetic regulation of the ACE gene might be more re levant to endurance physiology than the I/D polymorphism. (PubMed id 22096122) 1 Raleigh S.M. (2012) A meta-analysis of the association between angiotensin -converting enzyme insertion/deletion gene polymorphism and steroid-sensitive ne phrotic syndrome in children. (PubMed id 21946393) 1 Zhou T.B....Pang Y.S. (2012) The ACE I/D polymorphism in US adults: limited evidenc e of association with hypertension-related traits and sex-specific effects by ra ce/ethnicity. (PubMed id 21993364) 1 Ned R.M....Dowling N.F. (2012) ACE/ACE2 ratio and MMP-9 activity as potential biomark ers in tuberculous pleural effusions. (PubMed id 23091417) 1 Hsieh W.Y....Lin C.S. (2012) The ACE insertion/deletion polymorphism and its associ ation with metabolic syndrome. (PubMed id 22209668) 1 Xi B....Mi J. (2012) Gene polymorphisms of angiotensin-converting enzyme an d angiotensin II type 1 receptor among chronic kidney disease patients in a Chin ese population. (PubMed id 22147663) 1 Su S.L....Kao S.Y. (2012) Angiotensin-converting enzyme genotype and peripheral arterial disease in diabetic patients. (PubMed id 22144991) 1 Tseng C.H....Cheng J.C. (2012) Correlation between common genetic variants and risk f actors associated with prediction of cardiovascular diseases in dyslipidemic pat ients. (PubMed id 21919778) 1 Kotaska K....Prusa R. (2012) Synergism between paraoxonase Arg 192 and the angioten sin converting enzyme D allele is associated with severity of coronary artery di sease. (PubMed id 21681430) 1 Vaisi-Raygani A....Pourmotabbed T. (2012) Genetic polymorphism of angiotensin I-converting enzym e (ACE), but not angiotensin II type I receptor (ATr1), has a gender-specific ro le in panic disorder. (PubMed id 22353325) 1 Bayoglu B....Balcioglu I. (2012) No association between ACE polymorphism and risk of na sopharyngeal carcinoma. (PubMed id 22064901) 1 Li Z.H....Gao L.B. (2012) Expression of angiotensin-converting enzyme mRNA gene in the kidneys of patients with glomerulonephrites. (PubMed id 22982912) 1 Alnahal A.A....Zanaty A.F. (2012) A meta-analysis of the association between angiotensin -converting enzyme insertion/deletion gene polymorphism and Henoch-Schonlein pur pura nephritis risk in Asian children. (PubMed id 22325724) 1 Zhou T.B....Luo W. (2012) The Alu polymorphism of angiotensin I converting enzym e (ACE) and atherosclerosis, incident chronic diseases and mortality in an elder ly Chinese population. (PubMed id 22456784) 1 Woo J....Kwok T. (2012) Angiotensin-converting enzyme and progression of white matter lesions and brain atrophy--the SMART-MR study. (PubMed id 22214784) 1 Jochemsen H.M....Muller M. (2012) Serum angiotensin-converting enzyme level as a marker of fibrosis in patients with chronic hepatitis B. (PubMed id 22277254) 1 Purnak T....Ozaslan E. (2012) ACE I/D, ACTN3 R577X, PPARD T294C and PPARGC1A Gly482S er polymorphisms and physical fitness in Taiwanese late adolescent girls. (PubMed id 22247001) 1 Chiu L.L....Hsieh L.L. (2012) Association of angiotensin converting enzyme gene (I/D ) polymorphism with hypertension and type 2 diabetes. (PubMed id 22380495) 1 Zarouk W.A....Hamed M. (2012) Association of angiotensin converting enzyme (insertio n/deletion) gene polymorphism with essential hypertension in northern Indian sub jects. (PubMed id 22103580) 1 Srivastava K....Saluja D. (2012) The I/D polymorphism of angiotensin-converting enzyme gene in major depressive disorder and therapeutic outcome: a case-control study and meta-analysis. (PubMed id 22036796) 1 Wu Y....Yuan Y. (2012) Association of angiotensin-converting enzyme I/D polym orphism with heart failure: a meta-analysis. (PubMed id 22015653) 1 Bai Y....Wei Y. (2012) ACE gene I/D polymorphism and risk of sarcoidosis deve lopment in Turkish patients. (PubMed id 23030744) 1 Yilmaz D....Kunt Uzaslan E. (2012) Meta analysis of angiotensin-converting enzyme I/D pol ymorphism as a risk factor for preeclampsia in Chinese women. (PubMed id 22653650) 1 Zhong W.G....Zhao X. (2012) Meta-analysis of the relationship between ACE I/D gene polymorphism and end-stage renal disease in patients with diabetic nephropathy. (PubMed id 22385293) 1 Yu Z.Y....Zhou T.B. (2012) Single and combined influence of ACE and ACTN3 genotyp es on muscle phenotypes in octogenarians. (PubMed id 22045415) 1 Garatachea N....Lucia A. (2012) Association of ACE gene insertion/deletion polymorphis m with birth weight, blood pressure levels, and ACE activity in healthy children . (PubMed id 22647781) 1 Ajala A.R....Franco M.C. (2012) Association of angiotensin converting enzyme (ACE) gen e I/D polymorphism and rheumatoid arthritis. (PubMed id 23000565) 1 Yigit S....Ates O. (2012) Genetic associations of surfactant protein D and angio tensin-converting enzyme with lung disease in preterm neonates. (PubMed id 21960125) 1 Ryckman K.K....Murray J.C. (2012) Insertion/deletion (I/D) polymorphism of angiotensin-c onverting enzyme gene in steroid-resistant nephrotic syndrome for children: an u pdated meta-analysis. (PubMed id 22264093) 1 Zhou T.B. (2012) Angiotensin converting enzyme gene polymorphism is ass ociated with severity of coronary artery disease in men with high total choleste rol levels. (PubMed id 22307319) 1 Borzyszkowska J....Limon J. (2012) Angiotensin-converting enzyme insertion/deletion polym orphism is a risk factor for thoracic aortic aneurysm in patients with bicuspid or tricuspid aortic valves. (PubMed id 22245237) 1 Foffa I....Andreassi M.G. (2012) Genotypes and allele frequencies of angiotensin-conver ting enzyme (ACE) insertion/deletion polymorphism among Bahraini population with type 2 diabetes mellitus and related diseases. (PubMed id 22081332) 1 Al-Harbi E.M....Singh J. (2012) Association of ACE I/D gene polymorphism with vesicour eteral reflux susceptibility in children: a meta-analysis. (PubMed id 22396489) 1 Zhou T.B....Peng D.D. (2012) The association of ACE I/D gene polymorphism with seve re carotid atherosclerosis in patients undergoing carotid endarterectomy. (PubMed id 21984781) 1 Kolakovic A....Stankovic A. (2012) Angiotensin-converting enzyme deletion allele is benef icial for the longevity of Europeans. (PubMed id 21614448) 1 Zajc Petranovic M....Tomek-Roksandic S. (2012) Significant association between insertion/deletion pol ymorphism of the angiotensin-convertig enzyme gene and ankylosing spondylitis. (PubMed id 22876137) 1 Inanir A....Habiboglu A. (2012) Abnormal default-mode network in angiotensin convertin g enzyme D allele carriers with remitted geriatric depression. (PubMed id 22348891) 1 Wang Z....Zhang Z. (2012) The ACE gene D/I polymorphism as a modulator of severi ty of cystic fibrosis. (PubMed id 22874010) 1 Marson F.A....Ribeiro A.F. (2012) Association study of ACE polymorphisms and systemic lu pus erythematosus in Northern Chinese Han population. (PubMed id 22729880) 1 Gong A.M....Yang S.Z. (2012) Angiotensin converting enzyme insertion/deletion polym orphism and risk of pregnancy hypertensive disorders: a meta-analysis. (PubMed id 22086840) 1 Chen Z....Qi H. (2012) ACE gene polymorphism and atherosclerotic lesion of ca rotid artery among offsprings of type 2 diabetes mellitus. (PubMed id 22745143) 1 Purnamasari D....Syampurnawati M. (2012) Angiotensin-converting enzyme insertion/deletion polym orphism is associated with severe hypoxemia in pediatric ARDS. (PubMed id 22005825) 1 Cruces P....Repetto G.M. (2012) Angiotensin converting enzyme (ACE) and ACE2 bind inte grins and ACE2 regulates integrin signalling. (PubMed id 22523556) 1 Clarke N.E....Turner A.J. (2012) Association between insertion/deletion polymorphism in angiotensin-converting enzyme gene and acute lung injury/acute respiratory dist ress syndrome: a meta-analysis. (PubMed id 22938636) 1 Matsuda A....Wang P. (2012) Genetic markers and explosive leg-muscle strength in e lite Italian soccer players. (PubMed id 22648472) 1 Massidda M....Calo C.M. (2012) Association of AGT M235T and ACE I/D polymorphisms wit h the risk of ischemic stroke: meta-analysis in Han Chinese population. (PubMed id 22800767) 1 Wang B....Hua B. (2012) Angiotensin-converting enzyme (ACE) gene II genotype p rotects against the development of diabetic peripheral neuropathy in type 2 diab etes mellitus. (PubMed id 22607040) 1 Mansoor Q....Ismail M. (2012) Angiotensin-converting enzyme (CD143) specifies emergi ng lympho-hematopoietic progenitors in the human embryo. (PubMed id 22282502) 1 Sinka L....Tavian M. (2012) Epistatic effects of ACE I/D and AGT gene variants on left ventricular mass in hypertensive patients: the HyperGEN study. (PubMed id 21248783) 1 Lynch A.I....Arnett D.K. (2012) Interaction of MTHFR 1298C with ACE D allele augments the risk of diabetic nephropathy in Western Iran. (PubMed id 21942443) 1 Rahimi Z....Felehgari V. (2012) Angiotensin-converting enzyme gene I/D dimorphism does not play a major role in the susceptibility of Malaysian systemic lupus erythem atosus patients. (PubMed id 22576914) 1 Lian L.H....Chua K.H. (2012) Polymorphism of the angiotensin-converting enzyme gene and angiotensin-converting enzyme activity in transient tachypnea of neonate an d respiratory distress syndrome. (PubMed id 22339243) 1 Satar M....Yildizdas H.Y. (2012) Maternal deletion allele of Angiotensin-converting enz yme gene is associated with fetal growth restriction. (PubMed id 22150532) 1 Nakamura E....Hayashi T. (2012) Correlation of endothelin-1 concentration and angioten sin-converting enzyme activity with the staging of liver fibrosis. (PubMed id 22856224) 1 Kardum D....Banic M. (2012) Angiotensin converting enzyme DD genotype is associate d with acute coronary syndrome severity and sudden cardiac death in Taiwan: a ca se-control emergency room study. (PubMed id 22333273) 1 Chen Y.H....Yu C.P. (2012) Association of angiotensin I converting enzyme polymor phism as genetic risk factor in benign prostatic hyperplasia and prostate cancer . (PubMed id 22667764) 1 Hasanzad M....Ziaei S.A. (2012) Renin-angiotensin system genes polymorphism in Egyptia ns with premature coronary artery disease. (PubMed id 22387727) 1 Abd El-Aziz T.A....Shalaby S.M. (2012) Angiotensin-converting enzyme insertion/deletion gene polymorphism in lung cancer patients. (PubMed id 22339037) 1 Devic Pavlic S....Radojcic Badovinac A. (2012) Association between genetic polymorphism of the angiot ensin-converting enzyme and diabetic nephropathy: a meta-analysis comprising 26, 580 subjects. (PubMed id 21810896) 1 Wang F....Fan X. (2012) Meta-analysis of the association between the insertion /deletion polymorphism in ACE gene and coronary heart disease among the Chinese population. (PubMed id 22277253) 1 Zhou L....Li Y. (2012) Is the association between ACE genes and blood pressur e mediated by postnatal growth during the first 3 years? (PubMed id 22082670) 1 Min J....Park H. (2012) DD genotype of ACE gene in boys: may it be a risk fact or for minimal change nephrotic syndrome? (PubMed id 22017506) 1 Alasehirli B....Buyukcelik M. (2012) Association of angiotensin-converting enzyme functiona l gene I/D polymorphism with amnestic mild cognitive impairment. (PubMed id 22405893) 1 Zhang Z....Zhang Z. (2012) Association between angiotensin-converting enzyme I/D polymorphism and asthma risk: a meta-analysis involving 11,897 subjects. (PubMed id 22741763) 1 Ding Q.L....Deng Z.C. (2012) Relationship between angiotensin-converting enzyme ins ertion/deletion gene polymorphism and systemic lupus erythematosus/lupus nephrit is: a systematic review and metaanalysis. (PubMed id 22337243) 1 Zhou T.B....Peng D.D. (2012) Angiotensin-converting enzyme gene single polymorphism as a genetic biomarker of diabetic peripheral neuropathy: longitudinal prospect ive study. (PubMed id 22494836) 1 Jurado J....Zabaleta-Del-Olmo E. (2012) Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism and circulating ACE levels are not associated with outcome i n critically ill septic patients. (PubMed id 22017489) 1 Tsantes A....Armaganidis A. (2012) Influences of the G2350A polymorphism in the ACE gene on cardiac structure and function of ball game players. (PubMed id 22239999) 1 Jang Y. and Kim S.M. (2012) Angiotensin-converting enzyme insertion/deletion polym orphism contributes to ischemic stroke risk: a meta-analysis of 50 case-control studies. (PubMed id 23049705) 1 Zhang Z....Liu X. (2012) Association between polymorphisms of the renin-angiote nsin system and coronary artery disease in Chinese patients with type 2 diabetes . (PubMed id 22345093) 1 Lei H.P....Yu X.Y. (2012) Increased risk of myocardial infarction associated wit h angiotensin-converting enzyme gene polymorphism is age dependent. (PubMed id 21148050) 1 Hamelin B.A....Turgeon J. (2011) PPARg Pro12Ala and ACE ID polymorphisms are associated with BMI and fat distribution, but not metabolic syndrome. (PubMed id 22168210) 1 Passaro A....Zuliani G. (2011) The insertion/deletion (I/D) polymorphism in the Angio tensin-converting enzyme gene and cancer risk: a meta-analysis. (PubMed id 22151803) 1 Zhang Y....Fan H. (2011) Association between ACE polymorphism and risk of IgA nephropathy: a meta-analysis. (PubMed id 21357308) 1 Qin Y.H....Zhao Y.J. (2011) A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473) 1 Wagner S.A....Choudhary C. (2011) The presence of PAI-1 4G/5G and ACE DD genotypes incr eases the risk of early-stage AVF thrombosis in hemodialysis patients. (PubMed id 21332339) 1 GA1ngAPr Y....Candan F. (2011) Adipocyte-derived lipids increase angiotensin-convert ing enzyme (ACE) expression and modulate macrophage phenotype. (PubMed id 21116821) 1 Kohlstedt K....Fleming I. (2011) Initial characterization of the human central proteome. (PubMed id 21269460) 2 Burkard T.R.... Colinge J. (2011) Association of angiotensin-converting enzyme gene inse rtion/deletion polymorphism with high-altitude pulmonary oedema: a meta-analysis . (PubMed id 21525147) 1 Qi Y....Zhao D. (2011) Structural characterization of angiotensin I-converti ng enzyme in complex with a selenium analogue of captopril. (PubMed id 21810173) 1 Akif M....Acharya K.R. (2011) Lack of association between gene polymorphisms of Ang iotensin converting enzyme, Nod-like receptor 1, Toll-like receptor 4, FAS/FASL and the presence of Helicobacter pylori-induced premalignant gastric lesions a nd gastric cancer in Caucasians. (PubMed id 21864388) 1 Kupcinskas J....Malfertheiner P. (2011) A genetic contribution to risk for postoperative junct ional ectopic tachycardia in children undergoing surgery for congenital heart di sease. (PubMed id 21740877) 1 Borgman K.Y....Kannankeril P.J. (2011) Angiotensin-converting enzyme tag single nucleotide p olymorphisms in patients with intracerebral hemorrhage. (PubMed id 21258267) 1 Dardiotis E....Hadjigeorgiou G.M. (2011) Association of angiotensin-converting enzyme intron 1 6 insertion/deletion and angiotensin II type 1 receptor A1166C gene polymorphis ms with preeclampsia in South East of Iran. (PubMed id 21808598) 1 Salimi S....Naghavi A. (2011) Genetic influences on Alzheimer's disease: evidence o f interactions between the genes APOE, APOC1 and ACE in a sample population fro m the South of Brazil. (PubMed id 21533863) 1 Lucatelli J.F....de Andrade F.M. (2011) Insertion/deletion (I/D) polymorphism of angiotensin- converting enzyme gene in steroid-resistant nephrotic syndrome for children: a genetic association study and meta-analysis. (PubMed id 21787164) 1 Zhou T.B....Pang Y.S. (2011) An angiotensin I-converting enzyme mutation (Y465D) c auses a dramatic increase in blood ACE via accelerated ACE shedding. (PubMed id 21998728) 1 Danilov S.M....Sturrock E.D. (2011) Angiotensin-converting enzyme insertion/deletion poly morphism and severe hypoglycemia complicating type 2 diabetes: the Fremantle Di abetes Study. (PubMed id 21289265) 1 Davis W.A....Davis T.M. (2011) Angiotensin-converting enzyme gene polymorphism in pat ients with multiple sclerosis from Bosnia and Herzegovina. (PubMed id 21699406) 1 Klupka-Saric I....Ristic S. (2011) Insertion/deletion polymorphism of angiotensin I-conv erting enzyme gene is linked with chromophobe renal cell carcinoma. (PubMed id 21477733) 1 de Martino M....Marberger M. (2011) Influence of angiotensin-converting enzyme insertion/ deletion polymorphism on nitric oxide production in hypertensives and hyperchol esterolaemics. (PubMed id 21366648) 1 He S.W....Wong K.S. (2011) Epigenetic regulation of somatic angiotensin-converti ng enzyme by DNA methylation and histone acetylation. (PubMed id 21364323) 1 RiviA"re G....Frey F.J. (2011) Angiotensin-converting enzyme polymorphism affects ou tcome of local Chinese with acute lung injury. (PubMed id 21742477) 1 Lu X.M....Qiu H.B. (2011) Gender association of the angiotensin-converting enzym e gene with ischaemic stroke. (PubMed id 21421656) 1 Markoula S....Kyritsis A.P. (2011) Renin-angiotensin-aldosterone system genes and nonart eritic anterior ischemic optic neuropathy. (PubMed id 21633717) 1 Markoula S....Georgiou I. (2011) Angiotensin-converting enzyme/vitamin D receptor gene polymorphisms and bioelectrical impedance analysis in predicting athletic perf ormances of Italian young soccer players. (PubMed id 21747292) 1 Micheli M.L....Pacini S. (2011) Insertion/deletion polymorphism of the angiotensin-co nverting enzyme predicts left ventricular hypertrophy after renal transplantati on. (PubMed id 21620105) 1 Fedor R....TA^th A. (2011) ACE gene polymorphism and serum ACE activity in Irani ans type II diabetic patients with macroalbuminuria. (PubMed id 20830509) 1 Felehgari V....Vaisi-Raygani A. (2011) Interaction of A-240T and A2350G related genotypes of angiotensin-converting enzyme (ACE) is associated with decreased serum ACE act ivity and blood pressure in a healthy Iranian population. (PubMed id 21810419) 1 Firouzabadi N....Bakhshandeh H. (2011) Prognostic value of serum angiotensin-converting enzy me activity for outcome of community-acquired pneumonia. (PubMed id 21663571) 1 Meijvis S.C....van de Garde E.M. (2011) Effect of angiotensin converting enzyme gene I/D poly morphism in patients with metabolic syndrome in North Indian population. (PubMed id 21362306) 1 Mittal G....Khan A.S. (2011) Association of angiotensin converting enzyme insertion /deletion gene polymorphism with idiopathic nephrotic syndrome susceptibility in children: a meta-analysis. (PubMed id 21946394) 1 Zhou T.B....Yang K.P. (2011) [The role of angiotensin-converting enzyme gene polym orphism in development of erectile dysfunction in patients with metabolic syndr ome]. (PubMed id 21504074) 1 Gamidov S.I....Nosikov V.V. (2011) Association of angiotensin converting enzyme (ACE) ge ne I/D polymorphism and polycystic ovary syndrome (PCOS). (PubMed id 21939743) 1 Bayram B....Sahin F. (2011) The relationship of ACE and CETP gene polymorphisms w ith cardiovascular disease in a cohort of Asian Indian patients with and those without type 2 diabetes. (PubMed id 21185205) 1 Ganesan M....Pulakurthy U.R. (2011) Angiotensin-converting enzyme (rs4646994) and I+ ADDUC IN (rs4961) gene polymorphisms' study in primary spontaneous intracerebral hemo rrhage. (PubMed id 21339657) 1 Kalita J....Mittal B. (2011) No association of angiotensin I converting enzyme I/D polymorphism with domain-specific cognitive function in aged men without demen tia. (PubMed id 21833743) 1 Liu M.E....Ku Y.C. (2011) The relationship between angiotensin converting enzym e insertion/deletion polymorphism and age-related macular degeneration. (PubMed id 21417676) 1 UAser B....Cam S. (2011) Human metabolic individuality in biomedical and pharma ceutical research. (PubMed id 21886157) 1 Suhre K....Gieger C. (2011) [Relationship between angiotensin converting enzyme g ene polymorphism and essential hypertension in children]. (PubMed id 22099196) 1 Wu F....Ye C.F. (2011) Is the ACE I/D polymorphism associated with extreme l ongevity? A study on a Spanish cohort. (PubMed id 21330423) 1 Fiuza-Luces C....Lucia A. (2011) Gene variation in resistant hypertension: multilocus analysis of the angiotensin 1-converting enzyme, angiotensinogen, and endotheli al nitric oxide synthase genes. (PubMed id 21438754) 1 Yugar-Toledo J.C....JA_nior H.M. (2011) Common variants of the ACE gene and aneurysmal subara chnoid hemorrhage in a Danish population: a case-control study. (PubMed id 21709586) 1 StaalsA...Olsen N.V. (2011) Serum angiotensin I-converting enzyme levels and the therapeutic effects of octreotide in esophageal variceal hemorrhage. (PubMed id 21537155) 1 Zhan Q....Mu H.J. (2011) Multifactor dimensionality reduction analysis of MTHFR , PAI-1, ACE, PON1, and eNOS gene polymorphisms in patients with early onset cor onary artery disease. (PubMed id 21450592) 1 Agirbasli M....Williams S.M. (2011) Meta-analysis of ACE gene I/D polymorphism and bipola r disorder susceptibility. (PubMed id 21314245) 1 Zou Y.F....Huang F. (2011) Deletion allele of the ACE gene is not a risk factor f or asthma predisposition. (PubMed id 22420170) 1 Rad I.A....Rahimi-Rad M.H. (2011) ACE as a mechanosensor to shear stress influences the control of its own regulation via phosphorylation of cytoplasmic Ser(1270). (PubMed id 21901117) 1 Barauna V.G....Krieger J.E. (2011) Endothelial angiotensin-converting enzyme and neutral endopeptidase in isolated human umbilical vein: an effective bradykinin inacti vation pathway. (PubMed id 21651905) 1 Nowak W....Rothlin R.P. (2011) Association of angiotensin-converting enzyme, methyle ne tetrahydrofolate reductase and paraoxonase gene polymorphism and coronary ar tery disease in an Indian population. (PubMed id 21769819) 1 Pandey U....Pandey S. (2011) Angiotensin-converting enzyme gene and plasma protein level in Alzheimer's disease in Taiwanese. (PubMed id 21233092) 1 Yang Y.H....Liu C.K. (2011) Regional variation in angiotensin converting enzyme ac tivity in the human placenta. (PubMed id 21855137) 1 Brameld J.M....Pipkin F.B. (2011) Effects of human endothelial gene polymorphisms on ce llular responses to hyperglycaemia: role of NOS3 (Glu298Asp) and ACE (I/D) poly morphisms. (PubMed id 21844127) 1 Joshi M.S....Bauer J.A. (2011) Chloride regulation of enzyme turnover: application t o the role of chloride in photosystem II. (PubMed id 21366335) 1 Pokhrel R....Brudvig G.W. (2011) Angiotensin-converting enzyme gene polymorphism and N- Acetyl-b-D-glucosaminidase excretion in endemic nephropathy. (PubMed id 21757947) 1 Pecin I....Jelakovic B. (2011) ACE gene polymorphism in premature neonates with respi ratory distress syndrome. (PubMed id 21749216) 1 Yimenicioglu S....Coskun M.Y. (2011) Heterogeneous distribution of angiotensin I-convertin g enzyme (CD143) in the human and rat vascular systems: vessel, organ and speci es specificity. (PubMed id 21167844) 1 Metzger R....Danilov S.M. (2011) The peptide network regulated by angiotensin convertin g enzyme (ACE) in hematopoiesis. (PubMed id 21441775) 1 Shen X.Z. and Bernstein K.E. (2011) The role of ACE gene polymorphism on pathogenesis of ischemic stroke. (PubMed id 21979279) 1 Indrajaya T. (2011) Association between polymorphisms of the renin-angiot ensin system genes and breast cancer risk: a meta-analysis. (PubMed id 21638051) 1 Xi B....Li J. (2011) A multi-center study of ACE and the risk of late-onse t Alzheimer's disease. (PubMed id 21297258) 1 Belbin O....Kehoe P.G. (2011) The association of hypertension with renin-angiotensin system gene polymorphisms in the Lebanese population. (PubMed id 21628354) 1 Saab Y.B....Overall A.D. (2011) The association between angiotensin-converting enzyme insertion/deletion gene variant and risk of focal segmental glomerulosclerosis: a systematic review and meta-analysis. (PubMed id 21652690) 1 Zhou T.B....Yang K.P. (2011) Association of angiotensin I converting enzyme inserti on/deletion polymorphism with breast cancer: a meta-analysis. (PubMed id 21546404) 1 Sun M....Sun Y. (2011) [Genetic study of predisposition to community-acquired pneumonia]. (PubMed id 22312901) 1 Moroz V.V....Rubanovich A.V. (2011) Thrombotic gene polymorphisms and postoperative outcom e after coronary artery bypass graft surgery. (PubMed id 21955693) 1 Emiroglu O....Akar N. (2011) Haplotype-based association of ACE I/D, AT1R 1166A> C, and AGT M235T polymorphisms in renin-angiotensin-aldosterone system genes in Korean women with idiopathic recurrent spontaneous abortions. (PubMed id 21636204) 1 Choi Y.S....Kim N.K. (2011) The association between circulating angiotensin-conve rting enzyme and cardiovascular risk in the elderly: a cross-sectional study. (PubMed id 21273224) 1 Ljungberg L....Persson K. (2011) Effect of ACE polymorphisms on the association between noise and hypertension in a Pakistani population. (PubMed id 21436208) 1 Nawaz S.K. and Hasnain S. (2011) Protective effects of angiotensin-converting enzyme I /I and matrix metalloproteinase-3 6A/6A polymorphisms on dilatative pathology w ithin the ascending thoracic aorta. (PubMed id 21111627) 1 Lesauskaite V....Benetis R. (2011) APOE, MTHFR, LDLR and ACE polymorphisms among Angami a nd Lotha Naga populations of Nagaland, India. (PubMed id 21461956) 1 Murry B....Saraswathy K.N. (2011) Combined effect of Factor V Leiden, MTHFR, and angiote nsin-converting enzyme (insertion/deletion) gene mutations in hypertensive adult individuals: a population-based study from Sivas and Canakkale, Turkey. (PubMed id 21699409) 1 Demirel Y....Ozdemir O. (2011) Genetic variation of the human ACE and ACTN3 genes an d their association with functional muscle properties in Lithuanian elite athle tes. (PubMed id 21956137) 1 GineviA8ienA9 V....KuA8inskas V. (2011) Maternal/newborn genotype contribution of the renin-an giotensin system (Met235Thr, Thr174Met, I/D-ACE, A2350G-ACE, A1166C-AT2R1, C3123 A- AT2R2, 83A/G-REN) to the risk of pre-eclampsia: a Romanian study. (PubMed id 21436209) 1 Procopciuc L.M....Stamatian F. (2011) Association of echocardiographic left ventricular str ucture with the ACE D/I polymorphism: a meta-analysis. (PubMed id 21273223) 1 Yu Jin ....Staessen J.A. (2011) Contribution of deletion in angiotensin-converting en zyme but not A1166C angiotensin II type-1 receptor gene polymorphisms to clinic al outcomes in atherothrombotic disease. (PubMed id 21722816) 1 Le Hello C....Hamon M. (2011) Expression of ACE and ACE2 in patients with hypertens ive nephrosclerosis. (PubMed id 21346373) 1 Wang G....Szeto C.C. (2011) Elevated levels of circulating angiotensin converting enzyme in patients with hepatoportal sclerosis. (PubMed id 21290180) 1 Beyazit Y....Haznedaroglu I.C. (2011) [Study of the intronic polymorphism of the angiotensi n 1 converting enzyme among coronary Tunisians]. (PubMed id 21277558) 1 Chalghoum A....Miled A. (2011) Maternal and fetal angiotensin-converting enzyme gene insertion/deletion polymorphism not associated with pregnancy-induced hyperten sion in Chinese women. (PubMed id 21250908) 1 Yan W....Nie S. (2011) ACE I/D polymorphism in Polish patients with endometr iosis. (PubMed id 21568223) 1 KowalczyA8ska L.J....Malinowski A. (2011) Role of angiotensin-converting enzyme gene polymorphis m in persistent pulmonary hypertension of the newborn. (PubMed id 21418104) 1 De Jesus L.C....Quasney M.W. (2011) [Insertion/deletion polymorphism of angiotensin conve rting enzyme seriously modulates anesthetic outcome]. (PubMed id 21520587) 1 Terada K. (2011) ACE I/D gene polymorphism can't predict the steroid r esponsiveness in Asian children with idiopathic nephrotic syndrome: a meta-anal ysis. (PubMed id 21611163) 1 Zhou T.B....Zhao Y.J. (2011) Association of ACE ID and ACE G2350A polymorphism wit h increased blood pressure in persons exposed to different sound levels in Paki stan. (PubMed id 21305316) 1 Nawaz S.K. and Hasnain S. (2011) Impaired abdominal aortic wall integrity in elderly m en carrying the angiotensin-converting enzyme D allele. (PubMed id 21570325) 1 Ljungberg L.U....LAonne T. (2011) Offspring sex determines the impact of the maternal A CE I/D polymorphism on maternal glycaemic control during the last weeks of preg nancy. (PubMed id 21393357) 1 Hocher B....Chen Y.P. (2011) The ACE insertion/deletion polymorphism and risk of c ancer, a review and meta-analysis of the literature. (PubMed id 21395549) 1 Ruiter R....Stricker B.H. (2011) Impaired proteostasis contributes to renal tubular dy sgenesis. (PubMed id 21695262) 1 de Oliveira R.M....Outeiro T.F. (2011) Angiotensin-converting enzyme single nucleotide polym orphism is a genetic risk factor for cardiovascular disease: a cohort study of hypertensive patients. (PubMed id 21412245) 1 Kato N....Rakugi H. (2011) Association of Angiotensin-converting enzyme insertio n(I)/deletion (D) genotype in Alzheimer's disease patients of north Indian popu lation. (PubMed id 21770707) 1 Nirmal S....S V. (2011) Angiotensin-converting enzyme gene polymorphisms and T2DM in a case-control association study of the Bahraini population. (PubMed id 21207118) 1 Al-Harbi E.M....Singh J. (2011) Insertion/deletion polymorphism of angiotensin-1 conve rting enzyme is associated with metabolic syndrome in Hungarian adults. (PubMed id 21330420) 1 Fiatal S....Adany R. (2011) ACE gene sequence and nucleotide variants in IgA nephr opathy. (PubMed id 22173253) 1 Woo K.T....Wong K.S. (2011) Angiotensin-converting enzyme gene insertion/deletion polymorphism in patients with chronic pancreatitis and pancreatic cancer. (PubMed id 21654174) 1 Lukic S....Radojkovic D. (2011) Identification of genetic factors associated with sus ceptibility to angiotensin-converting enzyme inhibitors-induced cough. (PubMed id 21052031) 1 Grilo A....SA!ez M.E. (2011) Angiotensin converting enzyme (ACE) gene polymorphism in vitiligo: protective and predisposing effects of genotypes in disease susce ptibility and progression. (PubMed id 21382792) 1 Tippisetty S....Jahan P. (2011) No association between angiotensin I converting enzym e (ACE) I/D polymorphism and gastric cancer risk among Japanese. (PubMed id 21928698) 1 Hibi S....Hamajima N. (2011) ACE I/D polymorphism affects cognitive function and g ray-matter volume in amnestic mild cognitive impairment. (PubMed id 21108975) 1 Zhang Z....Zhang Z. (2011) Strong association between angiotensin I-converting e nzyme I/D polymorphism and unexplained recurrent miscarriage of Chinese women-- a case-control study. (PubMed id 21795738) 1 Zhang S....Ma X. (2011) Tetra primer ARMS-PCR relates folate/homocysteine pat hway genes and ACE gene polymorphism with coronary artery disease. (PubMed id 21567207) 1 Masud R. and Qureshi I.Z. (2011) Association between polymorphisms of the renin angiot ensin system and carotid stenosis. (PubMed id 21819925) 1 Sticchi E....Fatini C. (2011) Angiotensinogen t235 and angiotensin-converting enzym e insertion/deletion polymorphisms associated with the development of posttrans plantation diabetes mellitus in renal allograft recipients. (PubMed id 21440764) 1 A9zdemir B.H....Haberal M. (2011) Polymorphisms of the angiotensin-converting enzyme and angiotensinogen gene in patients with atrial fibrillation. (PubMed id 21436211) 1 Topal N.P....Yesildag O. (2011) The higher exercise intensity and the presence of alle le I of ACE gene elicit a higher post-exercise blood pressure reduction and nitr ic oxide release in elderly women: an experimental study. (PubMed id 22136292) 1 Santana H.A....Simoes H.G. (2011) Angiotensin-converting enzyme gene variant and its le vels: risk factors for myocardial infarction in a South Indian population. (PubMed id 20730398) 1 Pulla Reddy B....Jyothy A. (2010) Association between the angiotensin I-converting enzy me gene insertion/deletion polymorphism and endurance running speed in Japanese runners. (PubMed id 20574690) 1 Tobina T....Kiyonaga A. (2010) Study of a lipophilic captopril analogue binding to a ngiotensin I converting enzyme. (PubMed id 20014331) 7 Dalkas G.A....Cavelier F. (2010) Cytokine polymorphisms and Alzheimer disease: possibl e associations. (PubMed id 20213229) 1 Ribizzi G....Megna M. (2010) Genetical, histological, and clinical characteristics of IgA-negative mesangioproliferative glomerulopathy. (PubMed id 19937361) 1 Owada K....Watanabe T. (2010) A multilocus candidate approach identifies ACE and HI F1A as susceptibility genes for cellulite. (PubMed id 20059631) 1 Emanuele E....Geroldi D. (2010) Prevalence of angiotensin-converting enzyme, methylen etetrahydrofolate reductase, Factor V Leiden, prothrombin and apolipoprotein E gene polymorphisms in Morocco. (PubMed id 20687780) 1 They-They T.P....Nadifi S. (2010) Poor replication of candidate genes for major depress ive disorder using genome-wide association data. (PubMed id 20351714) 1 Bosker F.J....Nolen W.A. (2010) Polymorphisms of the angiotensin converting enzyme ge ne in Iranian Azeri Turkish women with unexplained recurrent pregnancy loss. (PubMed id 20722577) 1 Bagheri M....Nanbaksh F. (2010) Association analysis of TNFR2, VDR, A2M, GSTT1, GSTM1 , and ACE genes with rheumatoid arthritis in South Asians and Caucasians of Eas t Midlands in the United Kingdom. (PubMed id 20401725) 1 Ghelani A.M....Mastana S.S. (2010) Lack of association of ACE gene I/D polymorphism with obstructive sleep apnea syndrome in Turkish patients. (PubMed id 20449805) 1 Yakut T....Karadag M. (2010) Lack of association between antipsychotic-induced ext rapyramidal symptoms and polymorphisms in dopamine metabolism and transport gen es. (PubMed id 19892410) 1 GassA^ P....Lafuente A. (2010) Angiotensin-Converting Enzyme Polymorphism and Erecti le Dysfunction Complaints in the Brazilian Population. (PubMed id 20384940) 1 Andersen M.L....Tufik S. (2010) Investigation of ACE, ACE2 and AGTR1 genes for associ ation with nephropathy in Type 1 diabetes mellitus. (PubMed id 20854388) 1 Currie D....Maxwell A.P. (2010) [Correlation of metabolic syndrome clinical signs and genetic determinants at children with obese]. (PubMed id 21033077) 1 Shcherbakova M.I.u....Pronina L.A. (2010) Potential genetic risk factors in angiotensin-convert ing enzyme-inhibitor-induced angio-oedema. (PubMed id 20233181) 1 Bas M....Kojda G. (2010) The I/D polymorphism of the ACE1 gene is not associat ed with ischaemic stroke in Spanish individuals. (PubMed id 20402757) 1 Domingues-Montanari S....Montaner J. (2010) Advanced glycation end product-mediated matrix metall o-proteinase-9 and apoptosis via renin-angiotensin system in type 2 diabetes. (PubMed id 20215707) 1 Ishibashi T....Takeishi Y. (2010) Interactions among related genes of renin-angiotensin system associated with type 2 diabetes. (PubMed id 20592051) 1 Yang J.K....Ma Y.H. (2010) Association between Angiotensin-converting enzyme ins ertion/deletion genetic polymorphism and hypertension in a sample of lebanese p atients. (PubMed id 20939740) 1 Akra-Ismail M....Zgheib N.K. (2010) Alteration of resting brain function by genetic varia tion in angiotensin converting enzyme in amnestic-type mild cognitive impairmen t of Chinese Han. (PubMed id 20085788) 1 Zhang Z....Zhang Z. (2010) Null association between ACE gene I/D polymorphism an d diabetic nephropathy among multiethnic Malaysian subjects. (PubMed id 21031056) 1 Jayapalan J.J....Chan S.P. (2010) Impact of renin-angiotensin system polymorphisms on d evelopment of systolic dysfunction in hypertrophic cardiomyopathy. Evidence fro m a study of genotyped patients. (PubMed id 20975235) 1 Funada A....Yamagishi M. (2010) ACE and ACTN3 Genotypes in Older Women: Muscular Phen otypes. (PubMed id 21072744) 1 Lima R.M....Oliveira R.J. (2010) Genetic variants of connexin37 are associated with ca rotid intima-medial thickness and future onset of ischemic stroke. (PubMed id 21044781) 1 Leu H.B....Pan W.H. (2010) Functional polymorphisms in genes of the Angiotensin and Serotonin systems and risk of hypertrophic cardiomyopathy: AT1R as a potent ial modifier. (PubMed id 20594303) 1 Coto E....Alvarez V. (2010) Angiotensin II receptor type 1 1166 A/C and angiotens in converting enzyme I/D gene polymorphisms in a Dutch sarcoidosis cohort. (PubMed id 21319597) 1 Kruit A....van den Bosch J.M. (2010) Polymorphisms of plasminogen activator inhibitor-1, a ngiotensin converting enzyme and coagulation factor XIII genes in patients with recurrent spontaneous abortion. (PubMed id 20822334) 1 Aarabi M....Modarressi M.H. (2010) Association of angiotensin converting enzyme gene ins ertion/deletion polymorphism with lung cancer in Turkey. (PubMed id 20303010) 1 Nacak M....AynacioA9lu A.S. (2010) Cell signaling, internalization, and nuclear localiza tion of the angiotensin converting enzyme in smooth muscle and endothelial cell s. (PubMed id 20022959) 1 Lucero H.A....Gavras H. (2010) Amyloid-beta-Related Genes SORL1 and ACE are Genetica lly Associated With Risk for Late-onset Alzheimer Disease in the Chinese Popula tion. (PubMed id 20625269) 1 Ning M....He L. (2010) Association of the genetic polymorphisms of the ACE g ene and the eNOS gene with lupus nephropathy in northern Chinese population. (PubMed id 20540812) 1 Li X....Jin X. (2010) ACE Gene Insertion/Deletion Polymorphism Among Patien ts with Type 2 Diabetes, and Its Relationship with Metabolic Syndrome at Sardji to Hospital Yogyakarta, Indonesia. (PubMed id 20305326) 1 Sinorita H....Asdie A.H. (2010) Administration-time-dependent effects of spirapril on ambulatory blood pressure in uncomplicated essential hypertension. (PubMed id 20524801) 7 Hermida R.C....FernA!ndez J.R. (2010) Insertion/Deletion polymorphism of Angiotensin-conver ting enzyme as a risk factor for chronic allograft nephropathy. (PubMed id 20692468) 1 Fedor R....TA^th A. (2010) Association between angiotensin-converting enzyme ins ertion/deletion gene polymorphism and atrial fibrillation: a meta-analysis. (PubMed id 21076147) 1 Liu T....Li G. (2010) Investigation of association between Angiotensin-conv erting enzyme gene insertion/deletion polymorphism frequency in Turkish patient s with schizophrenia. (PubMed id 21158679) 1 Baskan N.M....Degirmenci I. (2010) Temporal trends in acute renal dysfunction among crit ically ill patients according to I/D and -262A > T ACE polymorphisms. (PubMed id 21103678) 1 Pedroso J.A....Alho C.S. (2010) Angiotensin-converting enzyme (ACE) genotypes and dis ability in hospitalized older patients. (PubMed id 21076879) 1 Seripa D....Pilotto A. (2010) Analyses of shared genetic factors between asthma and obesity in children. (PubMed id 20816195) 1 MelAcn E....Lasky-Su J. (2010) [Relationship between shen-deficiency syndrome and po lymorphism of angiotensin converting enzyme gene in longevous elders in Bama ar ea of Guangxi municipality] (PubMed id 20535922) 1 Zhang W.F....Wang A.J. (2010) Conformational fingerprinting of the angiotensin I-co nverting enzyme (ACE). 1. Application in sarcoidosis. (PubMed id 20873814) 1 Danilov S.M....Garcia J.G. (2010) Renin-Angiotensin System Associated with Risk of Uppe r GI Mucosal Injury Induced by Low Dose Aspirin : Renin Angiotensin System Gene s' Polymorphism. (PubMed id 20824505) 1 Shiotani A....Haruma K. (2010) Common Genetic Variation, Residential Proximity to Tr affic Exposure, and Left Ventricular Mass: The Multi-Ethnic Study of Atheroscle rosis. (PubMed id 20308035) 1 Van Hee V.C....Kaufman J.D. (2010) Association of angiotensinogen gene M235T and angiote nsin-converting enzyme gene I/D polymorphisms with essential hypertension in Ha n Chinese population: a meta-analysis. (PubMed id 20087216) 1 Ji L.D....Xu J. (2010) The D-allele of ACE insertion/deletion polymorphism i s associated with regional white matter volume changes and cognitive impairment in remitted geriatric depression. (PubMed id 20639003) 1 Hou Z....Bai F. (2010) Genetic effects on carotid intima-media thickness: sy stematic assessment and meta-analyses of candidate gene polymorphisms studied i n more than 5000 subjects. (PubMed id 20160191) 1 Paternoster L....Sudlow C.L. (2010) The angiotensin converting enzyme D allele is an inde pendent risk factor for early onset coronary artery disease. (PubMed id 20655894) 1 Vaisi-Raygani A....Pourmotabbed T. (2010) Angiotensin-converting enzyme insertion/deletion gene polymorphism in patients with familial multiple cerebral cavernous malformatio ns. (PubMed id 20488708) 1 Altas M....Elmaci I. (2010) Polymorphisms of the angiotensin converting enzyme ge ne in early-onset and late-onset pre-eclampsia. (PubMed id 20044877) 1 Uma R....Murphy D.J. (2010) Gene polymorphisms against DNA damage induced by hydr ogen peroxide in leukocytes of healthy humans through comet assay: a quasi-expe rimental study. (PubMed id 20444272) 1 Miranda-Vilela A.L....Klautau-GuimarALes M.N. (2010) Demonstrating the pharmacogenetic effects of angioten sin-converting enzyme inhibitors on long-term prognosis of diastolic heart fail ure. (PubMed id 19752885) 1 Wu C.K....Chiang F.T. (2010) Angiotensin-converting enzyme gene polymorphism and r isk of insulin resistance in PCOS. (PubMed id 20138007) 1 Celik O....Ozerol E. (2010) Association of deep venous thrombosis with prothrombo tic gene polymorphism identified in lung cancer cases. (PubMed id 21080081) 1 Arslan S....Akkurt I. (2010) The frequency of factor V Leiden mutation, ACE gene p olymorphism, serum ACE activity and response to ACE inhibitor and angiotensin I I receptor antagonist drugs in Iranians type II diabetic patients with microalb uminuria. (PubMed id 20853144) 1 Rahimi Z....Khazaie H. (2010) Renin-angiotensin system-related gene polymorphisms a re associated with risk of atrial fibrillation. (PubMed id 20826259) 1 Xiao P....Yin Y. (2010) Association of ACE and FACTOR VII gene variability wi th the risk of coronary heart disease in north Indian population. (PubMed id 20364300) 1 Sobti R.C....Talwar K.K. (2010) A prospective case-control study analyzes 12 thrombop hilic gene mutations in Turkish couples with recurrent pregnancy loss. (PubMed id 19906129) 1 Yenicesu G.I....Kocak N. (2010) Association between angiotensin converting enzyme G23 50A polymorphism and hypertension risk: a meta-analysis. (PubMed id 20639399) 1 Niu W....Zhu D. (2010) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 Rose J.E....Uhl G.R. (2010) Angiotensin-converting enzyme insertion/deletion gene polymorphism in a Tunisian healthy and acute myocardial infarction population. (PubMed id 20059382) 1 Mehri S....Ben Arab S. (2010) Physiogenomic analysis of statin-treated patients: do main-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615) 1 RuaA+o G....Wu A.H. (2010) No interactions between genetic polymorphisms and str essful life events on outcome of antidepressant treatment. (PubMed id 20022223) 1 Bukh J.D....Kessing L.V. (2010) Thrombophilic risk factors in the pathogenesis of non -arteritic anterior ischemic optic neuropathy patients. (PubMed id 20162297) 1 Felekis T....Asproudis I. (2010) Systematic analysis of candidate genes for Alzheimer' s disease in a French, genome-wide association study. (PubMed id 20413850) 1 Laumet G....Lambert J.C. (2010) A Pilot Study of Gene/Gene and Gene/Environment Inter actions in Alzheimer Disease. (PubMed id 20682755) 1 Ghebranious N....McCarty C.A. (2010) The I/D polymorphism of angiotensin-converting enzyme gene and asthma risk: a meta-analysis. (PubMed id 20880211) 1 Zhang Y.G....Fan H. (2010) Renin-angiotensin-aldosterone system gene polymorphis ms in coronary artery bypass graft surgery patients. (PubMed id 20223792) 1 Ragia G....Manolopoulos V.G. (2010) The N domain of human angiotensin-I-converting enzyme : the role of N-glycosylation and the crystal structure in complex with an N do main-specific phosphinic inhibitor, RXP407. (PubMed id 20826823) 1 Anthony C.S....Sturrock E.D. (2010) Is there an association between angiotensin convertin g enzyme (ACE) genotypes and abdominal aortic aneurysm? (PubMed id 20655774) 1 Obukofe B....Bown M.J. (2010) Synopsis of Preterm Birth Genetic Association Studies : The Preterm Birth Genetics Knowledge Base (PTBGene). (PubMed id 20484876) 1 Dolan S.M....Menon R. (2010) Association of ACE I/D polymorphism and recurrent mis carriages in an Italian population with a pre-modern reproductive pattern. (PubMed id 20450391) 1 Corbo R.M....Scacchi R. (2010) Influence of polymorphisms in candidate genes on earl y vascular alterations in obese children. (PubMed id 20142115) 1 Tounian A....Tounian P. (2010) Polymorphisms of the angiotensin converting enzyme ge ne in relation to intrauterine growth restriction. (PubMed id 20524904) 1 Uma R....Murphy D.J. (2010) Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086) 1 Bailey S.D....Anand S. (2010) Identification of type 2 diabetes-associated combinat ion of SNPs using support vector machine. (PubMed id 20416077) 1 Ban H.J....Park K.J. (2010) New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496) 1 Davila S....Seielstad M. (2010) Polymorphisms of the TNF-alpha and ACE genes, and ren al scarring in infants with urinary tract infection. (PubMed id 20022049) 1 Savvidou A....Galanakis E. (2010) Angiotensin-converting enzyme insertion/deletion poly morphism associated with acute respiratory distress syndrome among caucasians. (PubMed id 20515555) 1 Hu Z....Liao X. (2010) Insertion/deletion polymorphism and serum activity of the angiotensin-converting enzyme in Turkish patients with obstructive sleep a pnea syndrome. (PubMed id 20182789) 1 Ogus C....Gumuslu S. (2010) ACE inhibitor use was associated with lower serum deh ydroepiandrosterone concentrations in older men. (PubMed id 20403346) 1 Kwok T....Leung P.C. (2010) Can we predict top-level sports performance in power vs endurance events? A genetic approach. (PubMed id 20459474) 1 Buxens A....Lucia A. (2010) Cloning and characterization of a single-chain fragme nt of monoclonal antibody to ACE suitable for lung endothelial targeting. (PubMed id 20888351) 1 Balyasnikova I.V....Danilov S.M. (2010) Angiotensin converting enzyme I/D, angiotensinogen M2 35T and AT1-R A/C1166 gene polymorphisms in patients with acromegaly. (PubMed id 20361261) 1 Turgut S....Turgut G. (2010) Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study. (PubMed id 20577119) 1 Irvin M.R....Arnett D.K. (2010) Genetic Predisposition to Thrombophilia in Inflammato ry Bowel Disease. (PubMed id 20717043) 1 Cappello M....CraxA- A. (2010) Genetic variants in the renin-angiotensin-aldosterone system and salt sensitivity of blood pressure. (PubMed id 20486282) 1 Gu D....He J. (2010) Differential response to resistance training in CHF a ccording to ACE genotype. (PubMed id 20189663) 1 Williams A.D....Hare D.L. (2010) Frequencies of polymorphisms in cytokines, neurotrans mitters and adrenergic receptors in patients with complex regional pain syndrom e type I after distal radial fracture. (PubMed id 20173430) 1 Herlyn P....Gradl G. (2010) Are 'functionally related polymorphisms' of renin-angiotensin-aldosterone system gene polymorphisms associated with hypert ension? (PubMed id 20525211) 1 Hahntow I.N....Michel M.C. (2010) Genetic associations with mountain sickness in Han an d Tibetan residents at the Qinghai-Tibetan Plateau. (PubMed id 20570668) 1 Buroker N.E....Chen S.H. (2010) Cardiovascular adaptation, functional capacity and An giotensin-converting enzyme I/D polymorphism in elite athletes. (PubMed id 20609315) 1 Boraita A....HernA!ndez M. (2010) The COPD genetic association compendium: a comprehens ive online database of COPD genetic associations. (PubMed id 19933216) 1 Castaldi P.J....Trikalinos T.A. (2010) Angiotensin-converting enzyme gene polymorphism and r espiratory muscle function in infants. (PubMed id 20812241) 1 Dimitriou G....Mantagos S. (2010) Pharmacogenetic analysis of lipid responses to rosuva statin in Chinese patients. (PubMed id 20679960) 1 Hu M....Tomlinson B. (2010) ACE ID genotype and leg power in Rugby Union players. (PubMed id 20842098) 1 Bell W....Darlington S.E. (2010) Angiotensin I-converting enzyme insertion/deletion po lymorphism and increased risk of gall bladder cancer in women. (PubMed id 20438364) 1 Srivastava K....Mittal B. (2010) Genetic Risk Factors for Hepatopulmonary Syndrome in Patients With Advanced Liver Disease. (PubMed id 20346360) 1 Roberts K.E....Fallon M.B. (2010) A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064) 1 He C....Hunter D.J. (2010) CSF angiotensin II and angiotensin-converting enzyme levels in anti-aquaporin-4 autoimmunity. (PubMed id 20541774) 1 Matsushita T....Kira J. (2010) Angiotensin converting enzyme gene insertion/deletion polymorphism in patients with polycystic ovary syndrome. (PubMed id 20170341) 1 Karabulut A....Turgut G. (2010) Evaluation of gene polymorphisms in exercise-induced oxidative stress and damage. (PubMed id 20109103) 1 Akimoto A.K....Klautau-GuimarALes M.d.e. .N. (2010) ACE variants and risk of intracerebral hemorrhage rec urrence in amyloid angiopathy. (PubMed id 20381197) 1 Domingues-Montanari S....Montaner J. (2010) Angiotensin-converting enzyme gene I/D genotype affec ted metoprolol-induced reduction in 24-hour average heart rate. (PubMed id 20819590) 1 Liu L.W....Li Y.S. (2010) A genetic association study of maternal and fetal can didate genes that predispose to preterm prelabor rupture of membranes (PROM). (PubMed id 20673868) 1 Romero R....Menon R. (2010) Intermediate phenotypes identify divergent pathways t o Alzheimer's disease. (PubMed id 20574532) 1 Shulman J.M....De Jager P.L. (2010) Factor analysis of risk variables associated with met abolic syndrome in adult Asian Indians. (PubMed id 20877692) 1 Das M....Ghosh A. (2010) Genetic association study of the GNB3 C825T, the ACE I/D and the eNOS G894T polymorphisms and the risk to develop erectile dysfuncti on in a German ED population. (PubMed id 20629643) 1 Eisenhardt A....Sperling H. (2010) Effects of prolonged exercise on left ventricular mec hanical synchrony in long-distance runners: importance of previous exposure to endurance races. (PubMed id 20688470) 1 SahlAcn A....Braunschweig F. (2010) Renin angiotensin system polymorphisms in patients wi th metabolic syndrome (MetS). (PubMed id 20816596) 1 Procopciuc L.M....Zdrenghea D. (2010) SNP-by-fitness and SNP-by-BMI interactions from seven candidate genes and incident hypertension after 20 years of follow-up: the CAR DIA Fitness Study. (PubMed id 20944660) 1 Sarzynski M.A....Bouchard C. (2010) The I allele of the angiotensin converting enzyme I/D polymorphism confers protection against coronary artery disease. (PubMed id 20299978) 1 Abchee A....Zalloua P.A. (2010) ACE gene insertion/deletion polymorphism has a mild i nfluence on the acute development of left ventricular dysfunction in patients w ith ST elevation myocardial infarction treated with primary PCI. (PubMed id 21162760) 1 Parenica J....Spinar J. (2010) ACE I/D genotype, habitual physical activity, and blo od pressure in children. (PubMed id 20567050) 1 Sarzynski M.A....Heelan K. (2010) The relationship between angiotensin converting enzym e gene I/D polymorphism and QT dispersion in patients with hypertrophic cardiom yopathy. (PubMed id 20478904) 1 Kaya C.T....Erol C. (2010) Renin angiotensin system gene polymorphisms modify an giotensin-converting enzyme inhibitors' effect on cognitive function: the healt h, aging and body composition study. (PubMed id 20722844) 1 Hajjar I....Lipsitz L.A. (2010) Associations between genetic variants in the ACE, AGT , AGTR1 and AGTR2 genes and renal function in the Multi-ethnic Study of Atheros clerosis. (PubMed id 20606419) 1 Campbell C.Y....Post W.S. (2010) Hypoglycemia, S-ACE and ACE genotypes in a Danish nat ionwide population of children and adolescents with type 1 diabetes. (PubMed id 20546161) 1 Johannesen J....Mortensen H.B. (2010) Lack of association of genetic polymorphisms of angio tensin-converting enzyme gene I/D and glutathione-S-transferase enzyme T1 and M 1 with retinopathy of prematures. (PubMed id 21038299) 1 Yildiz M....Ozmen A. (2010) A genome-wide association study identifies new loci f or ACE activity: potential implications for response to ACE inhibitor. (PubMed id 20066004) 1 Chung C.M....Pan W.H. (2010) Vascular at-risk genotypes and disease severity in Le banese sickle cell disease patients. (PubMed id 20425806) 1 Farra C....Oberkanins C. (2010) Angiotensin-converting enzyme polymorphism in schizop hrenia, bipolar disorders, and their first-degree relatives. (PubMed id 20010451) 1 Kucukali