ACD Gene
protein-coding GIFtS: 50
GCID: GC16M067691
|
|
adrenocortical dysplasia homolog (mouse)
| |
Aliases for ACD gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Adrenocortical Dysplasia Homolog (Mouse)1 2 | | Ptop1 | | PIP12 3 5 | | Tint11 | | PTOP2 3 5 | | Tpp11 | | TINT12 3 5 | | Adrenocortical Dysplasia Protein Homolog2 | | TPP12 3 | | POT1 And TIN2 Organizing Protein2 | | POT1 And TIN2-Interacting Protein2 3 | | TIN2 Interacting Protein 12 | | Pip11 | | |
Export aliases for ACD gene to outside databasesPrevious GC identifers: GC16M066249 GC16M053564 |
Summaries for ACD gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for ACD: This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in thetelosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends.Through its interaction with other components, this protein plays a key role in the assembly and stabilization of thiscomplex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding differentisoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelatedTPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: ACD_HUMAN, Q96AP0Function: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length andprotection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protectschromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance andchromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-strandedtelomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhancestelomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a rolein organogenesis Gene Wiki entry for ACD
|
Genomic Views for ACD gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ACD gene promoter: AREB6 Pax-5 AML1a Nkx2-5 Other transcription factors
Search SABiosciences Chromatin IP Primers for ACD
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACD |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q22.1 Ensembl cytogenetic band: 16q22.1 HGNC cytogenetic band: 16q22ACD Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M067691: view genomic region
(about GC identifiers)
Start:
|
67,691,415 bp from pter |
End:
|
67,694,718 bp from pter |
Size:
|
3,304 bases |
Orientation:
|
minus strand |
|
Proteins for ACD gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ACD_HUMAN, Q96AP0 (See
protein sequence)Recommended Name: Adrenocortical dysplasia protein homolog Size: 544 amino acids; 57733 Da
Subunit: Component of the shelterin complex (telosome) composed of TERF1, TERF2, TINF2, TERF2IP ACD and POT1. Formsheterodimers with POT1. Identified in a complex with POT1 and single-stranded telomeric DNA. Interacts with STN1/OBFC1and TINF2
Subcellular location: Nucleus. Chromosome, telomere
Sequence caution: Sequence=AAX82621.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
1 PDB 3D structure from and Proteopedia for ACD:2I46 (3D)
 
Secondary accessions: Q562H5 Q9H8F9Alternative splicing: 2 isoforms: Q96AP0-1 Q96AP0-2 Explore the universe of human proteins at neXtProt for ACD: NX_Q96AP0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96AP0 ACD Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (3 alternative transcripts):
NP_001075955.1 NP_001075956.1 NP_075065.2 ENSEMBL proteins: ENSP00000219251 ENSP00000377496 Reactome Protein details: Q96AP0 Human Recombinant Protein Products for ACD:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
ACD for ontologies About GeneDecksing
ACD Antibody Products: Assay Products for ACD: |
Protein
Domains / Families for ACD gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ACD for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96AP0ProtoNet protein and cluster: Q96AP0 |
Function for ACD gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: ACD_HUMAN, Q96AP0Function: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length andprotection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protectschromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance andchromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-strandedtelomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhancestelomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a rolein organogenesis Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ACD for ontologies About GeneDecksing
Phenotypes: 10 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Acd):
ACD for phenotypes About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACD (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACD (see all 3) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for ACD | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACD | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACD  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACD |
|
Pathways & Interactions for ACD gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Meiotic Synapsis | | | 2 | Cell Cycle | | | 3 | Regulation of Telomerase | |
Pathway sources See GeneCards unified pathways Show all pathways
1 BioSystems Pathway for ACD 
5/7
Reactome Pathways for ACD (see all 7)
ACD for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ACD
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/91 Interacting proteins for ACD (Q96AP01, 2, 3 ENSP000003774964) via UniProtKB, MINT, STRING, and/or I2D (see all 91)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| UPF1 | Q929002, 3, ENSP000002628034 | MINT-8286631 MINT-8286600 MINT-8286615 I2D:
score=1 STRING: ENSP00000262803 | | XRCC6 | P129562, 3 | MINT-65113 I2D:
score=5 | | POT1 | Q9NUX51, 2, 3, ENSP000003502494 | EBI-717666,EBI-752420 MINT-68476 I2D:
score=6 STRING: ENSP00000350249 | | USP7 | Q930092, 3, ENSP000003435354 | MINT-2876099 I2D:
score=3 STRING: ENSP00000343535 | | LLGL1 | Q153342, 3, ENSP000003215374 | MINT-65112 I2D:
score=4 STRING: ENSP00000321537 | About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table
ACD for ontologies About GeneDecksing
|
Drugs & Compounds for ACD gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ACD for compounds About GeneDecksing
Browse Tocris compounds for ACD 1 Novoseek chemical compound relationship for ACD gene About this table
Search CenterWatch for drugs/clinical trials and news about ACD 
|
Transcripts for ACD gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ACD gene (3 alternative transcripts): NM_001082486.1 NM_001082487.1 NM_022914.2 Unigene Cluster for ACD: Adrenocortical dysplasia homolog (mouse) Hs.78019 [show with all ESTs]Unigene Representative Sequence: NM_0010824862 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000219251(uc002etp.4 uc002etq.4 uc002etr.4 uc010vjt.1) ENST00000393919
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ACD (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ACD (see all 3) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for ACD | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACD | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACD  |
Additional cDNA sequence: AF070535.1 AK023726.1 AK301090.1 AY502940.1 BC016904.1 13 DOTS entries: DT.312917 DT.95161809 DT.100016955 DT.95161808 DT.75126055 DT.100817189 DT.427457 DT.100817181 DT.120660503 DT.95161806 DT.100817182 DT.92436100 DT.97852587 24/221 AceView cDNA sequences (see all 221): CB131102 AA766528 BQ687392 BX091130 BQ645796 BM127444 CB961826 AY502940 BE393922 BM458309 BQ673954 BI755782 CR610904 AK023726 CB989933 BI752954 BM479322 BG910289 AI274041 AA772175 BG744354 AK125623 CR609290 CA489036 GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for ACD (see all 13) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | · | 1g | · | 1h | · | 1i | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 10a | · | 10b | ^ | 11 | ^ | 12 | |
| SP1: | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ACD
|
Expression for ACD gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ACD expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CGGCAAAAAA
 About this image See ACD Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ACD
SOURCE GeneReport for Unigene cluster: Hs.78019 SABiosciences Expression via Pathway-Focused PCR Array including ACD:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ACD Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ACD | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ACD | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ACD | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACD |
Orthologs for ACD gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ACD gene from 2/8 species (see all 8) About this table
ENSEMBL Gene Tree for ACD (if available) TreeFam Gene Tree for ACD (if available)  |
Paralogs for ACD gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ACD gene
ACD for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ACD PGOHUM00000238369 PGOHUM00000245719
|
Genomic Variants for ACD gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 16 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ACD (67691415 - 67694718 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ACD: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ACD |
|
Disorders
/ Diseases for ACD gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ACD for disorders About GeneDecksing
OMIM gene information: 609377
OMIM disorders: --
7 diseases for ACD: About MalaCardsadrenal hypoplasia hydronephrosis cerebrovascular disease laryngitis laryngeal cancer ataxia leukemia Human Genome Epidemiology (HuGE) Navigator: ACD (14 documents) Export disorders for ACD gene to outside databases
|
Publications for ACD gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ACD gene, integrated from 9 sources (see all 44): (articles sorted by number of sources associating them with ACD) | |  | Utopia: connect your pdf to the dynamic world of online information |
- PTOP interacts with POT1 and regulates its localization to telomeres. (PubMed id 15181449)1, 2, 3, 9 Liu D....Songyang Z. (2004)
- POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. (PubMed id 15231715)1, 2, 3, 9 Ye J.Z.-S.... de Lange T. (2004)
- TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres. (PubMed id 15316005)1, 2, 9 Ye J.Z.-S.... de Lange T. (2004)
- Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins. (PubMed id 15383534)1, 2, 9 Liu D.... Songyang Z. (2004)
- OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation. (PubMed id 19648609)1, 2 Wan M.... Liu D. (2009)
- The POT1-TPP1 telomere complex is a telomerase processivity factor. (PubMed id 17237768)1, 2 Wang F....Lei M. (2007)
- A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly. (PubMed id 16880378)1, 2 O'Connor M.S.... Songyang Z. (2006)
- Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator. (PubMed id 15537664)1, 2 Keegan C.E.... Hammer G.D. (2005)
- Shelterin: the protein complex that shapes and safeguards human telomeres. (PubMed id 16166375)1, 2 de Lange T. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
|
External Searches for ACD gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ACD gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ACD gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ACD gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ACD | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ACD gene: Search GeneIP for patents involving ACD
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ACD gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ACD | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ACD | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACD | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ACD | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ACD | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ACD |
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 | | ACD Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACD |
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| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACD |
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