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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ACD Gene

protein-coding   GIFtS: 50
GCID: GC16M067691

adrenocortical dysplasia homolog (mouse)

 Explore 7 diseases affiliated with
ACD via our new
 Human Malady Compendium 
Biological research products
for ACD
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Adrenocortical Dysplasia Homolog (Mouse)1 2     Ptop1
PIP12 3 5     Tint11
PTOP2 3 5     Tpp11
TINT12 3 5     Adrenocortical Dysplasia Protein Homolog2
TPP12 3     POT1 And TIN2 Organizing Protein2
POT1 And TIN2-Interacting Protein2 3     TIN2 Interacting Protein 12
Pip11     

External Ids:    HGNC: 250701   Entrez Gene: 650572   Ensembl: ENSG000001029777   OMIM: 6093775   UniProtKB: Q96AP03   

Export aliases for ACD gene to outside databases

Previous GC identifers: GC16M066249 GC16M053564


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ACD:
This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the
telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends.
Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this
complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different
isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated
TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ACD_HUMAN, Q96AP0
Function: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and
protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects
chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and
chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded
telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances
telomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role
in organogenesis

Gene Wiki entry for ACD


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010498.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ACD gene promoter:
         AREB6   Pax-5   AML1a   Nkx2-5   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ACD promoter sequence
   Search SABiosciences Chromatin IP Primers for ACD

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACD


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22

ACD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACD gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M067691:  view genomic region     (about GC identifiers)

Start:
67,691,415 bp from pter      End:
67,694,718 bp from pter
Size:
3,304 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ACD_HUMAN, Q96AP0 (See protein sequence)
Recommended Name: Adrenocortical dysplasia protein homolog  
Size: 544 amino acids; 57733 Da
Subunit: Component of the shelterin complex (telosome) composed of TERF1, TERF2, TINF2, TERF2IP ACD and POT1. Forms
heterodimers with POT1. Identified in a complex with POT1 and single-stranded telomeric DNA. Interacts with STN1/OBFC1
and TINF2
Subcellular location: Nucleus. Chromosome, telomere
Sequence caution: Sequence=AAX82621.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
1 PDB 3D structure from and Proteopedia for ACD:
2I46 (3D)    
Secondary accessions: Q562H5 Q9H8F9
Alternative splicing: 2 isoforms:  Q96AP0-1   Q96AP0-2   

Explore the universe of human proteins at neXtProt for ACD: NX_Q96AP0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96AP0

  • ACD Protein expression data from MOPED and PaxDb:    About this image 
    ACD Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001075955.1  NP_001075956.1  NP_075065.2  

    ENSEMBL proteins: 
     ENSP00000219251   ENSP00000377496  
    Reactome Protein details: Q96AP0
    Human Recombinant Protein Products for ACD: 
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    Novus Biologicals ACD Protein
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    Uscn Proteins for ACD

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000781chromosome, telomeric region IDA15380063
    GO:0000783nuclear telomere cap complex IDA16880378
    GO:0005622intracellular ----
    GO:0005654nucleoplasm TAS--

    ACD for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ACD


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ACD for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR021594 Telomere_Pot1

    Graphical View of Domain Structure for InterPro Entry Q96AP0

    ProtoNet protein and cluster: Q96AP0


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ACD_HUMAN, Q96AP0
    Function: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and
    protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects
    chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and
    chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded
    telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances
    telomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role
    in organogenesis

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding IPI15380063
    GO:0070182DNA polymerase binding IPI17237767
         
    ACD for ontologies           About GeneDecksing


    Phenotypes:
         10 MGI mutant phenotypes (inferred from 1 allele(MGI details for Acd):
     craniofacial  endocrine/exocrine gland  hearing/vestibular/ear  homeostasis/metabolism  integument 
     limbs/digits/tail  mortality/aging  pigmentation  renal/urinary system  reproductive system 

    ACD for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for ACD 

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    SwitchGear 3'UTR luciferase reporter plasmidACD 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Meiotic Synapsis
    Meiotic Synapsis1.00
    Chromosome Maintenance0.56
    Telomere clustering at the nuclear membrane0.82
    Packaging Of Telomere Ends0.54
    Meiosis0.70
    Telomere Maintenance0.38
    2Cell Cycle
    Cell Cycle1.00
    3Regulation of Telomerase
    Regulation of Telomerase1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for ACD 
        Regulation of Telomerase

    5/7        Reactome Pathways for ACD (see all 7)
        Telomere Maintenance
    Meiotic Synapsis
    Packaging Of Telomere Ends
    Cell Cycle
    Meiosis



    ACD for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ACD

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/91 Interacting proteins for ACD (Q96AP01, 2, 3 ENSP000003774964) via UniProtKB, MINT, STRING, and/or I2D (see all 91)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UPF1Q929002, 3, ENSP000002628034MINT-8286631 MINT-8286600 MINT-8286615 I2D: score=1 STRING: ENSP00000262803
    XRCC6P129562, 3MINT-65113 I2D: score=5 
    POT1Q9NUX51, 2, 3, ENSP000003502494EBI-717666,EBI-752420 MINT-68476 I2D: score=6 STRING: ENSP00000350249
    USP7Q930092, 3, ENSP000003435354MINT-2876099 I2D: score=3 STRING: ENSP00000343535
    LLGL1Q153342, 3, ENSP000003215374MINT-65112 I2D: score=4 STRING: ENSP00000321537
    About this table

    Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000723telomere maintenance TAS--
    GO:0001501skeletal system development IEA--
    GO:0001655urogenital system development IEA--
    GO:0006886intracellular protein transport IMP15181449
    GO:0016233telomere capping NAS17237767

    ACD for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ACD for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ACD
    1 Novoseek chemical compound relationship for ACD gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tin(2+) 98.1 13 15316005 (3), 15380063 (3), 15383534 (3), 15231715 (2) (see all 6)

    Search CenterWatch for drugs/clinical trials and news about ACD 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ACD gene (3 alternative transcripts): 
    NM_001082486.1  NM_001082487.1  NM_022914.2  

    Unigene Cluster for ACD:

    Adrenocortical dysplasia homolog (mouse)
    Hs.78019  [show with all ESTs]
    Unigene Representative Sequence: NM_001082486
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000219251(uc002etp.4 uc002etq.4 uc002etr.4 uc010vjt.1)
    ENST00000393919

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    Inhib. RNA
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    Additional cDNA sequence: 

    AF070535.1 AK023726.1 AK301090.1 AY502940.1 BC016904.1 

    13 DOTS entries:

    DT.312917  DT.95161809  DT.100016955  DT.95161808  DT.75126055  DT.100817189  DT.427457  DT.100817181 
    DT.120660503  DT.95161806  DT.100817182  DT.92436100  DT.97852587 

    24/221 AceView cDNA sequences (see all 221):

    CB131102 AA766528 BQ687392 BX091130 BQ645796 BM127444 CB961826 AY502940 
    BE393922 BM458309 BQ673954 BI755782 CR610904 AK023726 CB989933 BI752954 
    BM479322 BG910289 AI274041 AA772175 BG744354 AK125623 CR609290 CA489036 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for ACD (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g · 1h · 1i ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^
    SP1:                                                                          -                 -           -     -     -                                       
    SP2:                                                        -                 -                 -           -     -     -                                       
    SP3:                                                                                            -           -     -     -                                       
    SP4:                                                                          -                 -           -     -     -                                       
    SP5:                                                                          -                 -                                                               

    ExUns: 10a · 10b ^ 11 ^ 12
    SP1:                        
    SP2:                        
    SP3:                        
    SP4:                        
    SP5:                        


    ECgene alternative splicing isoforms for ACD

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ACD expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CGGCAAAAAA
    ACD Expression
    About this image
    See ACD Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ACD

    SOURCE GeneReport for Unigene cluster: Hs.78019
        SABiosciences Expression via Pathway-Focused PCR Array including ACD: 

              Telomeres & Telomerase in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACD

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ACD gene from 2/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Acd1 , 5 adrenocortical dysplasia1, 5 76.12(n)1
    65.77(a)1
      8 (53.04 cM)5
    4976521  NM_001012638.11  NP_001012656.11 
     1056981595 
    chicken
    (Gallus gallus)
    Aves ACD6
    Uncharacterized protein
    23(a)
    1 ↔ 1
    11(1029914-1036937)


    ENSEMBL Gene Tree for ACD (if available)
    TreeFam Gene Tree for ACD (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ACD gene

    ACD for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for ACD
    PGOHUM00000238369 PGOHUM00000245719


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/52 NCBI SNPs in ACD are shown (see all 52    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1150358971,2
    C,F--67690976(+) TTCCCG/AAAGAG 4 -- int1 ds50011Minor allele frequency- A:0.02WA 118
    rs764304781,2
    C--67691093(+) ATGGAC/GAGACC 4 -- ds5001 int10--------
    rs1174448441,2
    C,F--67691258(+) CAGGAC/TTGCTT 4 -- int1 ds50012Minor allele frequency- T:0.03NA EU 677
    rs1120114161,2
    C,F--67691273(+) CAGCCC/TTGACC 4 -- int1 ds50011Minor allele frequency- T:0.01EU 545
    rs1875276791,2
    --67691438(+) CCTGCC/TGCATG 4 -- ut310--------
    rs725565371,2
    C,F--67691477(-) CACACT/ACTGCT 4 -- ut31 int17Minor allele frequency- A:0.07MN NA EU 1112
    rs149201,2
    C,F,O--67691515(+) CACATC/AGGAGT 7 /P int1 syn112Minor allele frequency- A:0.03MN NA EU 6497
    rs1503870111,2
    C,F--67691516(+) ACATCG/AGAGTT 7 /P /L mis1 int12Minor allele frequency- A:0.00NA EU 5729
    rs10503461,2
    C,F--67691550(-) ACTTTC/TTGATG 7 L syn1 int1 ese34Minor allele frequency- T:0.00MN NA 4740
    rs1500780511,2
    C,F--67691552(+) TCAGAA/GAGTGC 7 S F int1 mis11Minor allele frequency- G:0.00NA 4552

    HapMap Linkage Disequilibrium report for ACD (67691415 - 67694718 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ACD: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ACD for disorders           About GeneDecksing

    OMIM gene information: 609377    OMIM disorders: --

    7 diseases for ACD:    About MalaCards
    adrenal hypoplasia    hydronephrosis    cerebrovascular disease    laryngitis
    laryngeal cancer    ataxia    leukemia

    Human Genome Epidemiology (HuGE) Navigator: ACD (14 documents)

    Export disorders for ACD gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ACD gene, integrated from 9 sources (see all 44):
    (articles sorted by number of sources associating them with ACD)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. PTOP interacts with POT1 and regulates its localization to telomeres. (PubMed id 15181449)1, 2, 3, 9 Liu D....Songyang Z. (2004)
    2. POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. (PubMed id 15231715)1, 2, 3, 9 Ye J.Z.-S.... de Lange T. (2004)
    3. TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres. (PubMed id 15316005)1, 2, 9 Ye J.Z.-S.... de Lange T. (2004)
    4. Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins. (PubMed id 15383534)1, 2, 9 Liu D.... Songyang Z. (2004)
    5. OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation. (PubMed id 19648609)1, 2 Wan M.... Liu D. (2009)
    6. The POT1-TPP1 telomere complex is a telomerase processivity factor. (PubMed id 17237768)1, 2 Wang F....Lei M. (2007)
    7. A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly. (PubMed id 16880378)1, 2 O'Connor M.S.... Songyang Z. (2006)
    8. Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator. (PubMed id 15537664)1, 2 Keegan C.E.... Hammer G.D. (2005)
    9. Shelterin: the protein complex that shapes and safeguards human telomeres. (PubMed id 16166375)1, 2 de Lange T. (2005)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 65057 HGNC: 25070 AceView: PTOP Ensembl:ENSG00000102977 euGenes: HUgn65057
    ECgene: ACD H-InvDB: ACD

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ACD Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ACD gene:
    Search GeneIP for patents involving ACD

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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