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ACCN2 Gene

protein-coding   GIFtS: 63

GC12P048737
amiloride-sensitive cation channel 2, neuronal
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for ACCN2

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
ASIC 2
ASIC1 1, 2, 3
ASIC1A 2
BNAC2 3
BNaC2 1, 2, 3
hBNaC2 1, 2
Descriptions
Acid-sensing ion channel 1 3
Brain sodium channel 2 3
Cation channel, amiloride-sensitive, neuronal, 2 2
acid-sensing ion channel 1a protein 2
amiloride-sensitive cation channel 2, neuronal 2
External Ids
HGNC: 1001
Entrez Gene: 412
UniProtKB: P783483
Ensembl: ENSG000001108817
Search outside databases for aliases for ACCN2 gene

Previous GC identifers: GC12P050746 GC12P050507 GC12P050168

Summaries
for ACCN2

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for ACCN2:
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The
members of this family are amiloride-sensitive sodium channels that contain intracellular N and C
termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many
cysteine residues with conserved spacing. The member encoded by this gene is expressed in most if
not all brain neurons, and it may be an ion channel subunit; however, its function as an ion
channel remains unknown. Alternative splicing of this gene generates 2 transcript products.
[provided by RefSeq]

UniProtKB/Swiss-Prot: ACCN2_HUMAN, P78348
Function: Cation channel with high affinity for sodium, which is gated by extracellular protons and
inhibited by the diuretic amiloride. Also permeable for Ca(2+), Li(+) and K(+). Generates a
biphasic current with a fast inactivating and a slow sustained phase. Mediates
glutamate-independent Ca(2+) entry into neurons upon acidosis. This Ca(2+) overloading is toxic
for cortical neurons and may be in part responsible for ischemic brain injury. Heteromeric channel
assembly seems to modulate channel properties. Functions as a postsynaptic proton receptor that
influences intracellular Ca(2+) concentration and calmodulin-dependent protein kinase II
phosphorylation and thereby the density of dendritic spines. Modulates activity in the circuits
underlying innate fear (By similarity)

Gene Wiki entry for ACCN2

Genomic Location
for ACCN2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the ACCN2 gene  

Entrez Gene cytogenetic band: 12q12   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q12

ACCN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P048737:     (about GC identifiers)

Start:
 48,737,754 bp from pter
End:
 48,763,661 bp from pter
Size:
 25,908 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000012.10  NT_029419.11  

Proteins
for ACCN2

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: ACCN2_HUMAN, P78348 (See protein sequence)
Recommended Name: Amiloride-sensitive cation channel 2, neuronal  
Size: 528 amino acids; 59967 Da
Subunit: Homotetramer or heterotetramer with other ASIC proteins (Probable). Interacts with STOM
and ACCN1 (By similarity). Interacts with PRKCABP
Subcellular location: Cell membrane; Multi-pass membrane protein (By similarity). Note=Localizes in
synaptosomes at dendritic synapses of neurons. Colocalizes with DLG4 (By similarity)
Miscellaneous: Potentiated by Ca(2+), Mg(2+), Ba(2+) and multivalent cations. Inhibited by
anti-inflammatory drugs like salicylic acid (By similarity). Potentiated by FMRFamide-related
neuropeptides. PH dependence may be regulated by serine proteases
Secondary accessions: P78349 Q96CV2
Alternative splicing: 2 isoforms:  P78348-2   P78348-1   (The splice variant from ASIC1a described in mouse and rat, which gives rise to an isoform with different N-termini (Asic1b), does not seem to exist in human)

Post-translational modifications:

  • Phosphorylation by PKA regulates interaction with PRKCABP and subcellular location. Phosphorylation
    by PKC may regulate the channel1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins (2 alternative transcripts): 
    NP_001086.2  NP_064423.2  


    ENSEMBL proteins: 
    ENSP00000228468 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Millipore Purified and/or Recombinant ACCN2 Protein
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (ACCN2)
    Human Recombinant Proteins from Abnova (ACCN2)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    2 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886 plasma membrane IEA--
    GO:0005887 integral to plasma membrane TAS9037075
    About this table

    Antibodies for ACCN2: 
    Browse Antibodies Central at Invitrogen
    Millipore Mono- and Polyclonal Antibodies for the study of ACCN2
    Sigma-Aldrich Antibodies for ACCN2
    Browse R&D Systems for Antibodies
    Antibodies from Abcam (ACCN2), each with their AbpromiseSM
    Browse Abnova for Monoclonal and Polyclonal Antibodies
    Novus Biologicals Antibody for ACCN2

    Assays for ACCN2: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for ACCN2

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro domains/families:
     IPR001873 Na+channel_ASC
     IPR004724 EnaC


       GeneDecks  ACCN2 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry P78348

    ProtoNet protein and cluster: P78348

    1 Blocks protein family: IPB001873 Na+ channel

    UniProtKB/Swiss-Prot: ACCN2_HUMAN, P78348
    Similarity: Belongs to the amiloride-sensitive sodium channel family

    Gene Function
    for ACCN2

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (ACCN2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ACCN2)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_020039

                  Applied Biosystems Silencer® siRNAs for ACCN2

                  Sigma-Aldrich siRNA and siRNA Panels for ACCN2  
                         Sigma-Aldrich shRNA for ACCN2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for ACCN2
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001095
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001095
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_001095 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_020039

    UniProtKB/Swiss-Prot: ACCN2_HUMAN, P78348
    Function: Cation channel with high affinity for sodium, which is gated by extracellular protons and
    inhibited by the diuretic amiloride. Also permeable for Ca(2+), Li(+) and K(+). Generates a
    biphasic current with a fast inactivating and a slow sustained phase. Mediates
    glutamate-independent Ca(2+) entry into neurons upon acidosis. This Ca(2+) overloading is toxic
    for cortical neurons and may be in part responsible for ischemic brain injury. Heteromeric channel
    assembly seems to modulate channel properties. Functions as a postsynaptic proton receptor that
    influences intracellular Ca(2+) concentration and calmodulin-dependent protein kinase II
    phosphorylation and thereby the density of dendritic spines. Modulates activity in the circuits
    underlying innate fear (By similarity)

    Genatlas biochemistry entry for ACCN2:
    neuronal amiloride-sensitive cation (sodium) channel 2,expressed in brain,with two alternatively
    spliced isoforms

    2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Accn2):

    behavior/neurologicalnervous system

    5 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005216 ion channel activity IEA--
    GO:0005509 calcium ion binding IEA--
    GO:0005515 protein binding IPI11802773
    GO:0015280 amiloride-sensitive sodium channel activity NAS--
    GO:0031402 sodium ion binding IEA--
    About this table

    Pathways & Interactions
    for ACCN2

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    2 Millipore Pathways for ACCN2
      inward current
      inward current

       GeneDecks  ACCN2 for the pathways selected above  
    About GeneDecksing

    2 Sigma-Aldrich "Your Favorite Gene" Pathways for  ACCN2  (Your Favorite Gene powered by Ingenuity) 
     Insulin Receptor Signaling
     Aldosterone Signaling in Epithelial Cells

       GeneDecks  ACCN2 for the pathways selected above  
    About GeneDecksing

     Gene Network CentralTM Interacting Genes and Proteins Network for  ACCN2 


    5 Interacting proteins for ACCN2 (ENSP000002284683 P783481) via UniProtKB, MINT, and/or STRING
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PICK1Q9NRD51STRING (score=.997) EBI-79189, EBI-79165
    STOMENSP000002867133STRING (score=.951)
    ACCN1ENSP000002258233STRING (score=.882)
    ABCB8ENSP000002975043STRING (score=.805)
    TRPV1ENSP000001746213STRING (score=.748)
    About this table

    5 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006811 ion transport IEA--
    GO:0006814 sodium ion transport NAS9037075
    GO:0006816 calcium ion transport IEA--
    GO:0007165 signal transduction TAS9037075
    GO:0009268 response to pH TAS9062189
    About this table

    Drugs & Compounds
    for ACCN2

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Enzo Life Sciences drugs & compounds for ACCN2
    Sigma-Aldrich Small Molecules for ACCN2:
    Inhibitor

    Browse Tocris compounds for ACCN2
    4 Novoseek chemical compound relationships for ACCN2 gene
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    sodium 46.52 5 17012229 (1), 9037075 (1), 16901942 (1), 11514582 (1)
    gdp 26.29 2 16562673 (1), 15952105 (1)
    hydrogen 11.87 8 17060608 (2), 10842183 (1), 16407431 (1), 10923674 (1)
    calcium 4.82 7 16407431 (2), 15369669 (1), 18673137 (1)
    About this table


    Transcripts
    for ACCN2

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (ACCN2)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (ACCN2)
                   OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_020039

                  Sigma-Aldrich siRNA and siRNA Panels for ACCN2  
                         Sigma-Aldrich shRNA for ACCN2  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001095  NM_020039  

    REFSEQ mRNAs for ACCN2 gene (2 alternative transcripts): 

    NM_001095.2   NM_020039.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001095  NM_020039  

                   OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001095
                                     Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001095
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_001095 

    Additional cDNA sequence: 

    AK290010.1 AK293960.1 BC013891.2 BC028722.1 EU078959.1 U78180.1 U78181.1 

    4 DOTS entries:

    DT.95370218  DT.100746318  DT.99990143  DT.99938511 

    24/80 AceView cDNA sequences (see all 80 ):

    Z40887 AI017398 AA442173 AI700050 AA322505 NM_020039 BC013891 BX115078 
    BG152517 NM_001095 AI336677 T06197 BF514399 BM726148 BM697220 AI553866 
    AW451342 AI762424 AW960463 BU634532 AV728855 BM930686 AW453079 BF347574 

    highest scoring ESTs for ACCN2:

    U78181 AA328056 AA364240 AA442069 AA442173 AA706443 AI017398 AI336677 AI620655 AI700050 

    Unigene Cluster for ACCN2:

    Amiloride-sensitive cation channel 2, neuronal
    Hs.274361  [show with all ESTs]
    Unigene Representative Sequence: NM_020039


    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ACCN2

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13
    SP1:                    -                                                           -                     
    SP2:                    -                                                                                 
    SP3:                                                                                                      
    SP4:                                                                                                      

    About this scheme

    ECgene alternative splicing isoforms for ACCN2

    1 Ensembl transcript including schematic representation:
    ENST00000228468  

    Expression
    for ACCN2

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    ACCN2 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for ACCN2

    1 / 2 / 3

    5 probe-sets matching ACCN2 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
    37953_s_at2, 3 U133-A 2 1.00 0.97 1.00 1.00 U78181 1.00 1.00 1.00 1

    		205156_s_at2, 3 U133-A 1 1.00 1.00 -- -- NM_020039 0.60 1.00 0.82 1
    37953_s_at2, 3 U133-A 2 1.00 0.97 -- -- U78181 1.00 1.00 1.00 1

    		205156_s_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    37953_s_at2 U133Plus2 2 1.00 0.97 -- -- -- -- -- -- --
    GeneDecks  ACCN2 for binary patterns associated with the probe-sets selected above  
    About GeneDecksing
    About this table    
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: CCTAGCCTGC

    SOURCE GeneReport for Unigene cluster: Hs.274361

    Expression variation in blood from EXPOLDB for ACCN2

    UniProtKB/Swiss-Prot: ACCN2_HUMAN, P78348
    Tissue specificity: Expressed in most or all neurons

    Orthologs
    for ACCN2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for ACCN2 gene from 5/7 species (see all 7 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    chimpanzee
    (Pan troglodytes)    		 ACCN21   -- amiloride-sensitive cation channel 2, neuronal 99.56(n)
    100(a)    		 451888  XM_001155207.1  XP_001155207.1 
    rat
    (Rattus norvegicus)    		 Accn21   -- amiloride-sensitive cation channel 2, neuronal 92.08(n)
    98.48(a)    		 79123  NM_024154.1  NP_077068.1 
    mouse
    (Mus musculus)    		 Accn21, 5 155
    		 amiloride-sensitive cation channel 2, neuronal1, 5 91.76(n)1
    98.29(a)1    		 114191  NM_009597.11  NP_033727.11 
     AB2080225  AI8436105  (see all 11)
    chicken
    (Gallus gallus)    		 ACCN21   -- amiloride-sensitive cation channel 2, neuronal 84.03(n)
    89.54(a)    		 426883  NM_001040467.1  NP_001035557.1 
    zebrafish
    (Danio rerio)    		 accn2c1   -- amiloride-sensitive cation channel 2 c 69.35(n)
    70.66(a)    		 407670  NM_214789.1  NP_999954.1 
    About this table        Species with no ortholog for ACCN2

    ENSEMBL Gene Tree for ACCN2

    Paralogs
    for ACCN2

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for ACCN2 gene
    ACCN12  ACCN32  

    SNPs/Variants
    for ACCN2

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/112 NCBI SNPs in ACCN2 are shown (see all 112 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 52)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 12 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs5904601,2
    		A,C,F,H48736243(-) GCTGGG/AGGGTT 2 -- ng516Minor allele frequency- A:0.23EU EA WA 600
    rs8361851,2
    		C,F,H48737095(+) ACATGT/CAGGTG 2 -- ng517Minor allele frequency- C:0.07EA NA MN EU 1388
    --
    rs7067941,2
    		C,F48762425(-) CAGCCA/C/TGGTCT 2 -- ut31 ese35EA NA MN 422
    rs8606991,2
    		C,F48737369(-) GTCCCC/TCTCCC 2 -- ng51 trp31Minor allele frequency- T:0.03MN 184
    rs10514971,2
    		C,H48762753(+) GCCTTC/AGCCTG 2 -- ut31 ese35Minor allele frequency- A:0.00MN EU EA WA 600
    rs6535761,2
    		C,F,H48738975(-) GCCAGC/GGAGCC 2 S/S syn1 ese34Minor allele frequency- G:0.10EA MN 1826
    rs23070801,2
    		A,F48760022(+) GGCAAA/GGAGCT 2 K/K syn11Minor allele frequency- G:0.01EA 1500
    rs4504231,2
    		A,C,F,H,O48744172(+) AGGCCA/GACCTG 2 -- int16Minor allele frequency- G:0.19EA WA NA 410
    rs7067931,2
    		A,C,F,H,O48754036(-) ACTGCC/TGGGAA 2 -- int112Minor allele frequency- T:0.22EA NA EU WA 784
    rs6130661,2
    		A,C,F,H,O48740358(+) CAGCCT/GTGTTA 2 -- int16Minor allele frequency- G:0.13EA WA NA 438
    About this table

    HapMap Linkage Disequilibrium images for ACCN2 (up to first 250kb)

    Disorders & Mutations
    for ACCN2

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 602866

    7 Novoseek disease relationships for ACCN2 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    acidosis 76.24 3 10842183 (1), 12578970 (1), 19120019 (1)
    ischemic brain injury 64.23 1 17261712 (1)
    ischemia 38.09 9 15369669 (1), 15932031 (1), 16685601 (1), 18334630 (1) (see all 6)
    glioma 26.44 4 12244121 (1), 12584187 (1), 17883949 (1)
    stroke 7.46 3 17446049 (1), 17204502 (1)
    inflammation 0.00 6 11588175 (1)
    tumors 0.00 1 12584187 (1)
    About this table

    Human Genome Epidemiology Navigator: ACCN2 (2 documents)

    Medical News
    for ACCN2

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for ACCN2

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/83 PubMed articles for ACCN2 gene (see all 83 ):

    Search for ACCN2

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing ACCN2

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 41 HGNC: 100 AceView: ACCN2 Ensembl:ENSG00000110881 euGenes: HUgn41
    ECgene: ACCN2 H-InvDB: ACCN2

    Other Databases showing ACCN2

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing ACCN2

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section

    		   --

    Licensable Technologies
    for ACCN2

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for ACCN2

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for ACCN2:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for ACCN2-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
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