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Aliases for ACBD7 Gene

Aliases for ACBD7 Gene

  • Acyl-CoA Binding Domain Containing 7 2 3
  • Acyl-Coenzyme A Binding Domain Containing 7 2 3
  • Acyl-CoA-Binding Domain-Containing Protein 7 3
  • BA455B2.2 3

External Ids for ACBD7 Gene

Previous GeneCards Identifiers for ACBD7 Gene

  • GC10U900450
  • GC10M015157
  • GC10M015117
  • GC10M015031

Summaries for ACBD7 Gene

GeneCards Summary for ACBD7 Gene

ACBD7 (Acyl-CoA Binding Domain Containing 7) is a Protein Coding gene. GO annotations related to this gene include lipid binding and fatty-acyl-CoA binding. An important paralog of this gene is DBI.

UniProtKB/Swiss-Prot for ACBD7 Gene

  • Binds medium- and long-chain acyl-CoA esters

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACBD7 Gene

Genomics for ACBD7 Gene

Regulatory Elements for ACBD7 Gene

Genomic Location for ACBD7 Gene

Start:
15,075,475 bp from pter
End:
15,088,776 bp from pter
Size:
13,302 bases
Orientation:
Minus strand

Genomic View for ACBD7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ACBD7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ACBD7 Gene

Proteins for ACBD7 Gene

  • Protein details for ACBD7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N6N7-ACBD7_HUMAN
    Recommended name:
    Acyl-CoA-binding domain-containing protein 7
    Protein Accession:
    Q8N6N7
    Secondary Accessions:
    • A6NCI2
    • B3KTG8

    Protein attributes for ACBD7 Gene

    Size:
    88 amino acids
    Molecular mass:
    9790 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ACBD7 Gene

neXtProt entry for ACBD7 Gene

Proteomics data for ACBD7 Gene at MOPED

Post-translational modifications for ACBD7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ACBD7 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ACBD7 Gene

Domains for ACBD7 Gene

Protein Domains for ACBD7 Gene

Suggested Antigen Peptide Sequences for ACBD7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N6N7

UniProtKB/Swiss-Prot:

ACBD7_HUMAN :
  • Q8N6N7
Domain:
  • Contains 1 ACB (acyl-CoA-binding) domain.
Family:
  • Belongs to the ACBD7 family.
genes like me logo Genes that share domains with ACBD7: view

No data available for Gene Families for ACBD7 Gene

Function for ACBD7 Gene

Molecular function for ACBD7 Gene

UniProtKB/Swiss-Prot Function: Binds medium- and long-chain acyl-CoA esters

Gene Ontology (GO) - Molecular Function for ACBD7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000062 fatty-acyl-CoA binding IEA --
GO:0008289 lipid binding IEA --
genes like me logo Genes that share ontologies with ACBD7: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ACBD7 Gene

Localization for ACBD7 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ACBD7 Gene COMPARTMENTS Subcellular localization image for ACBD7 gene
Compartment Confidence
cytosol 3
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ACBD7 Gene

Pathways for ACBD7 Gene

SuperPathways for ACBD7 Gene

No Data Available

Interacting Proteins for ACBD7 Gene

Gene Ontology (GO) - Biological Process for ACBD7 Gene

None

No data available for Pathways by source for ACBD7 Gene

Compounds for ACBD7 Gene

(32) HMDB Compounds for ACBD7 Gene

Compound Synonyms Cas Number PubMed IDs
(2E)-Decenoyl-CoA
  • (E)-S-2-decenoate Coenzyme A
10018-95-8
(2E)-Dodecenoyl-CoA
  • 2-trans-Dodecenoyl-Coenzyme A
1066-12-2
(2E)-Hexadecenoyl-CoA
  • trans-2-Hexadecenoyl-CoA
4460-95-1
(2E)-Octenoyl-CoA
  • (E)-S-2-octenoate Coenzyme A
10018-94-7
(2E)-Tetradecenoyl-CoA
  • (2E)-Tetradecenoyl-Coenzyme A
38795-33-4
genes like me logo Genes that share compounds with ACBD7: view

Transcripts for ACBD7 Gene

mRNA/cDNA for ACBD7 Gene

(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ACBD7 Gene

Acyl-CoA binding domain containing 7:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ACBD7 Gene

No ASD Table

Relevant External Links for ACBD7 Gene

GeneLoc Exon Structure for
ACBD7
ECgene alternative splicing isoforms for
ACBD7

Expression for ACBD7 Gene

mRNA expression in normal human tissues for ACBD7 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ACBD7 Gene

This gene is overexpressed in Brain - Amygdala (7.4), Brain - Caudate (basal ganglia) (6.7), Brain - Nucleus accumbens (basal ganglia) (6.5), Brain - Putamen (basal ganglia) (5.1), Brain - Frontal Cortex (BA9) (4.6), Brain - Hippocampus (4.1), and Brain - Anterior cingulate cortex (BA24) (4.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ACBD7 Gene

SOURCE GeneReport for Unigene cluster for ACBD7 Gene Hs.644598

genes like me logo Genes that share expressions with ACBD7: view

No data available for mRNA Expression by UniProt/SwissProt for ACBD7 Gene

Orthologs for ACBD7 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ACBD7 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ACBD7 35
  • 98.86 (n)
  • 97.73 (a)
ACBD7 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ACBD7 35
  • 82.58 (n)
  • 81.82 (a)
ACBD7 36
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 43 (a)
ManyToMany
ACBD7 35
  • 91.29 (n)
  • 86.36 (a)
mouse
(Mus musculus)
Mammalia Acbd7 35
  • 82.95 (n)
  • 82.95 (a)
Acbd7 16
Acbd7 36
  • 83 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ACBD7 36
  • 84 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Acbd7 35
  • 82.95 (n)
  • 82.95 (a)
chicken
(Gallus gallus)
Aves ACBD7 35
  • 82.58 (n)
  • 79.55 (a)
ACBD7 36
  • 80 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ACBD7 36
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia acbd7 35
  • 76.14 (n)
  • 77.27 (a)
zebrafish
(Danio rerio)
Actinopterygii acbd7 35
  • 66.67 (n)
  • 68.97 (a)
acbd7 36
  • 68 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000546 35
  • 61.74 (n)
  • 55.68 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG15829 36
  • 39 (a)
ManyToMany
CG5804 36
  • 41 (a)
ManyToMany
CG8498 35
  • 56.82 (n)
  • 56.82 (a)
CG8628 36
  • 48 (a)
ManyToMany
CG8629 36
  • 48 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea acbp-1 36
  • 52 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ACB1 36
  • 44 (a)
OneToMany
Species with no ortholog for ACBD7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ACBD7 Gene

ENSEMBL:
Gene Tree for ACBD7 (if available)
TreeFam:
Gene Tree for ACBD7 (if available)

Paralogs for ACBD7 Gene

Paralogs for ACBD7 Gene

Selected SIMAP similar genes for ACBD7 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ACBD7 Gene

genes like me logo Genes that share paralogs with ACBD7: view

Variants for ACBD7 Gene

Sequence variations from dbSNP and Humsavar for ACBD7 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs1041158 -- 15,083,972(+) GGGCA(A/G)CGGTG intron-variant
rs2025717 -- 15,080,778(+) TCTAA(A/C)CTCTT intron-variant
rs4565803 -- 15,088,473(+) CTCCT(A/G)CCTTG intron-variant
rs4604779 -- 15,088,517(+) GGAAG(A/G)GTTGC intron-variant
rs4748141 -- 15,082,125(+) CTACT(A/G)AAAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ACBD7 Gene

Variant ID Type Subtype PubMed ID
nsv831794 CNV Loss 17160897
dgv618n71 CNV Gain 21882294

Relevant External Links for ACBD7 Gene

HapMap Linkage Disequilibrium report
ACBD7

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACBD7 Gene

Disorders for ACBD7 Gene

No disorders were found for ACBD7 Gene.

No data available for UniProtKB/Swiss-Prot for ACBD7 Gene

Publications for ACBD7 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3

Products for ACBD7 Gene

Sources for ACBD7 Gene

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