ACBD7 Gene
protein-coding GIFtS : 38
GCID: GC10 M015117
acyl-CoA binding domain containing 7 (Previous name: acyl-Coenzyme A binding domain containing 7 )
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Aliasesfor ACBD7 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Acyl-CoA Binding Domain Containing 7 1 2 Acyl-Coenzyme A Binding Domain Containing 71 2 BA455B2.21 FLJ382191 Acyl-CoA-Binding Domain-Containing Protein 72
Export aliases for ACBD7 gene to outside databases Previous GC identifers: GC10U900450 GC10M015157 GC10M015031
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Summariesfor ACBD7 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: ACBD7_HUMAN, Q8N6N7 Function : Binds medium- and long-chain acyl-CoA esters
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Genomic Viewsfor ACBD7 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000010.10 NC_018921.1 NT_008705.16 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ACBD7 gene promoter: C/EBPbeta CUTL1 NF-AT Evi-1 NF-AT4 NRF-2 NF-AT2 NF-AT3 LyF-1 NF-AT1 Other transcription factors Search SABiosciences Chromatin IP Primers for ACBD7 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat ACBD7
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 10p13 Ensembl cytogenetic band: 10p13 HGNC cytogenetic band: 10p13 ACBD7 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 10 GeneLoc Exon Structure
GeneLoc location for GC10M015117: view genomic region
(about GC identifiers )
Start:
15,117,474 bp from pter
End:
15,130,775 bp from pter
Size:
13,302 bases
Orientation:
minus strand
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Proteinsfor ACBD7 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: ACBD7_HUMAN, Q8N6N7 (See
protein sequence )Recommended Name: Acyl-CoA-binding domain-containing protein 7 Size : 88 amino acids; 9790 Da
1 PDB 3D structure from and Proteopedia for ACBD7 :3EPY (3D)
 
Secondary accessions : A6NCI2 B3KTG8Explore the universe of human proteins at neXtProt for ACBD7: NX_Q8N6N7 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q8N6N7 ACBD7 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_001034933.1 ENSEMBL proteins: ENSP00000367453 Human Recombinant Protein Products for ACBD7: ACBD7 Antibody Products: Assay Products for ACBD7:
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Protein
Domains / Familiesfor ACBD7 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
ACBD7 for domains About GeneDecksing 2 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q8N6N7 ProtoNet protein and cluster: Q8N6N7
1 Blocks protein family : IPB000582 Acyl-coA-binding protein UniProtKB/Swiss-Prot: ACBD7_HUMAN, Q8N6N7 Similarity : Belongs to the ACBD7 familySimilarity : Contains 1 ACB (acyl-CoA-binding) domain
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Functionfor ACBD7 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: ACBD7_HUMAN, Q8N6N7 Function : Binds medium- and long-chain acyl-CoA esters
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0000062 fatty-acyl-CoA binding
IEA -- GO:0008289 lipid binding
IEA --
ACBD7 for ontologies About GeneDecksing Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ACBD7 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ACBD7OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: ACBD7 (NM_001039844 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACBD7 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ACBD7
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACBD7
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Pathways & Interactionsfor ACBD7 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ACBD7 STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)2 Interacting proteins for ACBD7 (ENSP00000367453 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table
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Drugs & Compoundsfor ACBD7 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for ACBD7 10/32 HMDB Compounds for ACBD7 (see all 32 ) About this table Search CenterWatch for drugs/clinical trials and news about ACBD7
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Transcriptsfor ACBD7 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for ACBD7 gene: NM_001039844.2 Unigene Clusters for ACBD7:
Acyl-CoA binding domain containing 7 Hs.644598 [show with all ESTs ] , Hs.723069 [show with all ESTs ] Unigene Representative Sequences: NM_001039844 , AK295169 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000356189 (uc001inv.3 ) ENST00000496890 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ACBD7 (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ACBD7OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: ACBD7 (NM_001039844 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ACBD7 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ACBD7
Additional cDNA sequence: AK295169.1 XM_002342972.1
2 DOTS entries : DT.75106633 DT.99938261
GeneLoc Exon Structure
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Expression for ACBD7 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ACBD7 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AGCCACCGCGAbout this image ACBD7 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
1 LifeMap In Vivo Development Anatomical Compartment/Cell Tissue Anatomical Compartment
Cell Category (developmental path) Eye Outer Nuclear Layer Mature Rod Cells Photoreceptors, Retina Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See ACBD7 Protein Expression from SPIRE MOPED and PaxDB SOURCE GeneReport for Unigene clusters: Hs.644598 Hs.723069 SABiosciences Custom PCR Arrays for ACBD7 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for ACBD7Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat ACBD7 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ACBD7 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ACBD7 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACBD7
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Orthologsfor ACBD7 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for ACBD7 gene from 8/22 species (see all 22 ) About this table
ENSEMBL Gene Tree for ACBD7 (if available)TreeFam Gene Tree for ACBD7 (if available)
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Paralogsfor ACBD7 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for ACBD7 gene ACBD5 2 ACBD4 2 DBI 2 7 SIMAP similar genes for ACBD7 using alignment to 1 protein entry: ACBD7_HUMAN :DBI BRL ECI2 HCA64 PECI ACBD5 ACBD4
ACBD7 for paralogs About GeneDecksing 2 Pseudogenes.org Pseudogenes for ACBD7 PGOHUM00000242560 PGOHUM00000247122
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Genomic Variantsfor ACBD7 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 10 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for ACBD7 (15117474 - 15130775 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ACBD7: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ACBD7
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Disorders
/ Diseasesfor ACBD7 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section --
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Publicationsfor ACBD7 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ACBD7 gene integrated from 9 sources : (articles sorted by number of sources associating them with ACBD7) Utopia : connect your pdf to the dynamic world of online information
The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054) 1 , 2 Deloukas P.... Rogers J. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002)
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External Searches for ACBD7 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ACBD7 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing ACBD7 gene
(According to HUGE )
About This Section --
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Specialized Databases showing ACBD7 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for ACBD7 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for ACBD7 gene: Search GeneIP for patents involving ACBD7 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ACBD7 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for ACBD7 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for ACBD7 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for ACBD7 OriGene Protein Over-expression Lysate for ACBD7 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for ACBD7 Browse 3'-UTR reporter clones for miRNA target validation OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ACBD7 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ACBD7 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for ACBD7 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for ACBD7 OriGene Custom Protein Services for ACBD7 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ACBD7 QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ACBD7 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat ACBD7 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat ACBD7 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ACBD7 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ACBD7
Search Tocris compounds for ACBD7
ACBD7 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACBD7
Search ThermoFisher Antibodies for ACBD7
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ACBD7
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Intellectual Property for ACBD7
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