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Aliases for ACBD7 Gene

Aliases for ACBD7 Gene

  • Acyl-CoA Binding Domain Containing 7 2 3
  • Acyl-Coenzyme A Binding Domain Containing 7 2 3
  • BA455B2.2 3

External Ids for ACBD7 Gene

Previous GeneCards Identifiers for ACBD7 Gene

  • GC10U900450
  • GC10M015157
  • GC10M015117
  • GC10M015031

Summaries for ACBD7 Gene

GeneCards Summary for ACBD7 Gene

ACBD7 (Acyl-CoA Binding Domain Containing 7) is a Protein Coding gene. GO annotations related to this gene include lipid binding and fatty-acyl-CoA binding. An important paralog of this gene is DBI.

UniProtKB/Swiss-Prot for ACBD7 Gene

  • Binds medium- and long-chain acyl-CoA esters

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACBD7 Gene

Genomics for ACBD7 Gene

Regulatory Elements for ACBD7 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ACBD7 Gene

15,075,475 bp from pter
15,088,776 bp from pter
13,302 bases
Minus strand

Genomic View for ACBD7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for ACBD7 Gene

Proteins for ACBD7 Gene

  • Protein details for ACBD7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Acyl-CoA-binding domain-containing protein 7
    Protein Accession:
    Secondary Accessions:
    • A6NCI2
    • B3KTG8

    Protein attributes for ACBD7 Gene

    88 amino acids
    Molecular mass:
    9790 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ACBD7 Gene

neXtProt entry for ACBD7 Gene

Proteomics data for ACBD7 Gene at MOPED

Post-translational modifications for ACBD7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ACBD7 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ACBD7 Gene

Domains & Families for ACBD7 Gene

Protein Domains for ACBD7 Gene

Suggested Antigen Peptide Sequences for ACBD7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 ACB (acyl-CoA-binding) domain.
  • Belongs to the ACBD7 family.
  • Contains 1 ACB (acyl-CoA-binding) domain.
  • Belongs to the ACBD7 family.
genes like me logo Genes that share domains with ACBD7: view

No data available for Gene Families for ACBD7 Gene

Function for ACBD7 Gene

Molecular function for ACBD7 Gene

UniProtKB/Swiss-Prot Function:
Binds medium- and long-chain acyl-CoA esters

Gene Ontology (GO) - Molecular Function for ACBD7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000062 fatty-acyl-CoA binding IEA --
GO:0008289 lipid binding IEA --
genes like me logo Genes that share ontologies with ACBD7: view

Phenotypes for ACBD7 Gene

GenomeRNAi human phenotypes for ACBD7:
genes like me logo Genes that share phenotypes with ACBD7: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ACBD7

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ACBD7 Gene

Localization for ACBD7 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ACBD7 Gene

Pathways & Interactions for ACBD7 Gene

SuperPathways for ACBD7 Gene

No Data Available

Interacting Proteins for ACBD7 Gene

Gene Ontology (GO) - Biological Process for ACBD7 Gene


No data available for Pathways by source and SIGNOR curated interactions for ACBD7 Gene

Drugs & Compounds for ACBD7 Gene

(1) Drugs for ACBD7 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Propionyl-CoA Experimental Pharma 0

(31) Additional Compounds for ACBD7 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
  • (E)-S-2-decenoate
  • (E)-S-2-decenoate CoA
  • (E)-S-2-decenoate Coenzyme A
  • (E)-S-2-decenoic acid
  • 2-trans-Decenoyl-CoA
  • (2E)-Dodec-2-enoyl-CoA
  • (2E)-Dodec-2-enoyl-Coenzyme A
  • 2-trans-Dodecenoyl-CoA
  • 2-trans-Dodecenoyl-Coenzyme A
  • (2E)-Hexadecenoyl-CoA
  • (2E)-Hexadecenoyl-Coenzyme A
  • trans-2-Hexadecenoyl-CoA
  • trans-2-Hexadecenoyl-Coenzyme A
  • (E)-S-2-octenoate
  • (E)-S-2-octenoate CoA
  • (E)-S-2-octenoate Coenzyme A
  • (E)-S-2-octenoic acid
  • 2,3-trans-Octenoyl coenzyme A
  • (2E)-Tetradecenoyl-CoA
  • (2E)-Tetradecenoyl-Coenzyme A
  • Trans-tetra-dec-2-enoyl-CoA
  • Trans-tetra-dec-2-enoyl-CoA.
  • Trans-tetra-dec-2-enoyl-Coenzyme A
genes like me logo Genes that share compounds with ACBD7: view

Transcripts for ACBD7 Gene

mRNA/cDNA for ACBD7 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ACBD7 Gene

Acyl-CoA binding domain containing 7:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ACBD7

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ACBD7 Gene

No ASD Table

Relevant External Links for ACBD7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ACBD7 Gene

mRNA expression in normal human tissues for ACBD7 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ACBD7 Gene

This gene is overexpressed in Brain - Amygdala (x7.4), Brain - Caudate (basal ganglia) (x6.7), Brain - Nucleus accumbens (basal ganglia) (x6.5), Brain - Putamen (basal ganglia) (x5.1), Brain - Frontal Cortex (BA9) (x4.6), Brain - Hippocampus (x4.1), and Brain - Anterior cingulate cortex (BA24) (x4.1).

Protein differential expression in normal tissues from HIPED for ACBD7 Gene

This gene is overexpressed in Fetal Brain (24.5), Brain (16.2), and Skin (6.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ACBD7 Gene

SOURCE GeneReport for Unigene cluster for ACBD7 Gene Hs.644598

genes like me logo Genes that share expression patterns with ACBD7: view

Protein tissue co-expression partners for ACBD7 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for ACBD7 Gene

Orthologs for ACBD7 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ACBD7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ACBD7 35
  • 82.58 (n)
  • 81.82 (a)
ACBD7 36
  • 82 (a)
(Canis familiaris)
Mammalia ACBD7 35
  • 91.29 (n)
  • 86.36 (a)
-- 36
  • 43 (a)
(Mus musculus)
Mammalia Acbd7 35
  • 82.95 (n)
  • 82.95 (a)
Acbd7 16
Acbd7 36
  • 83 (a)
(Pan troglodytes)
Mammalia ACBD7 35
  • 98.86 (n)
  • 97.73 (a)
ACBD7 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Acbd7 35
  • 82.95 (n)
  • 82.95 (a)
(Monodelphis domestica)
Mammalia ACBD7 36
  • 84 (a)
(Gallus gallus)
Aves ACBD7 35
  • 82.58 (n)
  • 79.55 (a)
ACBD7 36
  • 80 (a)
(Anolis carolinensis)
Reptilia ACBD7 36
  • 72 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia acbd7 35
  • 76.14 (n)
  • 77.27 (a)
(Danio rerio)
Actinopterygii acbd7 35
  • 66.67 (n)
  • 68.97 (a)
acbd7 36
  • 68 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000546 35
  • 61.74 (n)
  • 55.68 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8498 35
  • 56.82 (n)
  • 56.82 (a)
CG15829 36
  • 39 (a)
CG5804 36
  • 41 (a)
CG8628 36
  • 48 (a)
CG8629 36
  • 48 (a)
(Caenorhabditis elegans)
Secernentea acbp-1 36
  • 52 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ACB1 36
  • 44 (a)
Species with no ortholog for ACBD7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ACBD7 Gene

Gene Tree for ACBD7 (if available)
Gene Tree for ACBD7 (if available)

Paralogs for ACBD7 Gene

Paralogs for ACBD7 Gene

(7) SIMAP similar genes for ACBD7 Gene using alignment to 1 proteins: Pseudogenes for ACBD7 Gene

genes like me logo Genes that share paralogs with ACBD7: view

Variants for ACBD7 Gene

Sequence variations from dbSNP and Humsavar for ACBD7 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs1041158 -- 15,083,972(+) GGGCA(A/G)CGGTG intron-variant
rs2025717 -- 15,080,778(+) TCTAA(A/C)CTCTT intron-variant
rs4565803 -- 15,088,473(+) CTCCT(A/G)CCTTG intron-variant
rs4604779 -- 15,088,517(+) GGAAG(A/G)GTTGC intron-variant
rs4748141 -- 15,082,125(+) CTACT(A/G)AAAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ACBD7 Gene

Variant ID Type Subtype PubMed ID
nsv831794 CNV Loss 17160897
dgv618n71 CNV Gain 21882294

Variation tolerance for ACBD7 Gene

Residual Variation Intolerance Score: 69.06% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.55; 11.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ACBD7 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACBD7 Gene

Disorders for ACBD7 Gene

Relevant External Links for ACBD7

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ACBD7: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ACBD7 Gene

Publications for ACBD7 Gene

  1. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 67
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for ACBD7 Gene

Sources for ACBD7 Gene

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