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Aliases for ACBD6 Gene

Aliases for ACBD6 Gene

  • Acyl-CoA Binding Domain Containing 6 2 3
  • Acyl-Coenzyme A Binding Domain Containing 6 2

External Ids for ACBD6 Gene

Previous GeneCards Identifiers for ACBD6 Gene

  • GC01M177496
  • GC01M176989
  • GC01M178523
  • GC01M151488

Summaries for ACBD6 Gene

GeneCards Summary for ACBD6 Gene

ACBD6 (Acyl-CoA Binding Domain Containing 6) is a Protein Coding gene. GO annotations related to this gene include lipid binding and fatty-acyl-CoA binding.

UniProtKB/Swiss-Prot for ACBD6 Gene

  • Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACBD6 Gene

Genomics for ACBD6 Gene

Regulatory Elements for ACBD6 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ACBD6 Gene

180,269,653 bp from pter
180,502,954 bp from pter
233,302 bases
Minus strand

Genomic View for ACBD6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ACBD6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ACBD6 Gene

Proteins for ACBD6 Gene

  • Protein details for ACBD6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Acyl-CoA-binding domain-containing protein 6
    Protein Accession:
    Secondary Accessions:

    Protein attributes for ACBD6 Gene

    282 amino acids
    Molecular mass:
    31151 Da
    Quaternary structure:
    • Monomer.

    Three dimensional structures from OCA and Proteopedia for ACBD6 Gene

neXtProt entry for ACBD6 Gene

Proteomics data for ACBD6 Gene at MOPED

Post-translational modifications for ACBD6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ACBD6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ACBD6 Gene

Domains for ACBD6 Gene

Gene Families for ACBD6 Gene

  • ANKRD :Ankyrin repeat domain containing

Suggested Antigen Peptide Sequences for ACBD6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9BR61
  • Contains 1 ACB (acyl-CoA-binding) domain.
  • Contains 2 ANK repeats.
genes like me logo Genes that share domains with ACBD6: view

Function for ACBD6 Gene

Molecular function for ACBD6 Gene

UniProtKB/Swiss-Prot Function: Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids.

Gene Ontology (GO) - Molecular Function for ACBD6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000062 fatty-acyl-CoA binding IEA --
GO:0005515 protein binding --
GO:0008289 lipid binding IEA --
genes like me logo Genes that share ontologies with ACBD6: view

Animal Model Products

CRISPR Products

miRNA for ACBD6 Gene

miRTarBase miRNAs that target ACBD6

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ACBD6

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ACBD6 Gene

Localization for ACBD6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ACBD6 Gene


Subcellular locations from

Jensen Localization Image for ACBD6 Gene COMPARTMENTS Subcellular localization image for ACBD6 gene
Compartment Confidence
nucleus 4
cytosol 3
vacuole 1

Gene Ontology (GO) - Cellular Components for ACBD6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with ACBD6: view

Pathways for ACBD6 Gene

SuperPathways for ACBD6 Gene

No Data Available

Interacting Proteins for ACBD6 Gene

Gene Ontology (GO) - Biological Process for ACBD6 Gene


No data available for Pathways by source for ACBD6 Gene

Compounds for ACBD6 Gene

(32) HMDB Compounds for ACBD6 Gene

Compound Synonyms Cas Number PubMed IDs
  • (E)-S-2-decenoate Coenzyme A
  • 2-trans-Dodecenoyl-Coenzyme A
  • trans-2-Hexadecenoyl-CoA
  • (E)-S-2-octenoate Coenzyme A
  • (2E)-Tetradecenoyl-Coenzyme A
genes like me logo Genes that share compounds with ACBD6: view

Transcripts for ACBD6 Gene

mRNA/cDNA for ACBD6 Gene

Unigene Clusters for ACBD6 Gene

Acyl-CoA binding domain containing 6:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ACBD6

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ACBD6 Gene

No ASD Table

Relevant External Links for ACBD6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ACBD6 Gene

mRNA expression in normal human tissues for ACBD6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ACBD6 Gene

SOURCE GeneReport for Unigene cluster for ACBD6 Gene Hs.200051

mRNA Expression by UniProt/SwissProt for ACBD6 Gene

Tissue specificity: Detected in placenta and spleen (at protein level). Detected in placenta, umbilical cord blood, CD34-positive hematopoietic progenitor cells and bone marrow.
genes like me logo Genes that share expressions with ACBD6: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for ACBD6 Gene

Orthologs for ACBD6 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for ACBD6 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ACBD6 35
  • 99.53 (n)
  • 100 (a)
(Bos Taurus)
Mammalia ACBD6 35
  • 90.31 (n)
  • 89.36 (a)
(Canis familiaris)
Mammalia ACBD6 35
  • 90.43 (n)
  • 89.36 (a)
(Mus musculus)
Mammalia Acbd6 35
  • 86.52 (n)
  • 85.82 (a)
Acbd6 16
(Rattus norvegicus)
Mammalia Acbd6 35
  • 87.12 (n)
  • 86.88 (a)
(Gallus gallus)
Aves ACBD6 35
  • 74.03 (n)
  • 77.53 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.6444 35
tropical clawed frog
(Silurana tropicalis)
Amphibia acbd6 35
  • 65.65 (n)
  • 63.74 (a)
Str.87 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5351 35
(Danio rerio)
Actinopterygii acbd6 35
  • 67.37 (n)
  • 67.93 (a)
wufc18d09 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000752 35
  • 46.88 (n)
  • 38.36 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG33713 35
  • 43.71 (n)
  • 34.65 (a)
(Caenorhabditis elegans)
Secernentea acbp-5 35
  • 43.83 (n)
  • 31.94 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons ACBP1 35
  • 48.1 (n)
  • 40.65 (a)
(Oryza sativa)
Liliopsida Os04g0681900 35
  • 49.48 (n)
  • 41.73 (a)
Species with no ortholog for ACBD6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ACBD6 Gene

Gene Tree for ACBD6 (if available)
Gene Tree for ACBD6 (if available)

Paralogs for ACBD6 Gene

No data available for Paralogs for ACBD6 Gene

Variants for ACBD6 Gene

Sequence variations from dbSNP and Humsavar for ACBD6 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs822703 -- 180,299,085(-) AGAAG(C/T)ATATA intron-variant
rs822704 -- 180,328,641(+) TATGA(C/T)AAGTG intron-variant
rs822705 -- 180,329,032(+) CATCA(C/T)CCCTG intron-variant
rs822706 -- 180,331,293(+) TTTGT(C/T)ATAAT intron-variant
rs863720 -- 180,327,646(+) ATTAA(C/T)TTTAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ACBD6 Gene

Variant ID Type Subtype PubMed ID
nsv832004 CNV Gain 17160897
nsv466239 CNV Gain 19166990
esv2673419 CNV Deletion 23128226
esv2650355 CNV Deletion 19546169
nsv527918 CNV Gain 19592680
esv2576257 CNV Deletion 19546169
esv2136642 CNV Deletion 18987734
esv1001564 CNV Deletion 20482838
esv5032 CNV Deletion 18987735
esv2719918 CNV Deletion 23290073
esv1123070 CNV Deletion 17803354
esv6088 CNV Loss 19470904
nsv3766 CNV Insertion 18451855
esv2664302 CNV Deletion 23128226

Relevant External Links for ACBD6 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACBD6 Gene

Disorders for ACBD6 Gene

Relevant External Links for ACBD6

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with ACBD6: view

No data available for UniProtKB/Swiss-Prot for ACBD6 Gene

Publications for ACBD6 Gene

  1. Characterization of an acyl-coenzyme A binding protein predominantly expressed in human primitive progenitor cells. (PMID: 18268358) Soupene E. … Kuypers F.A. (J. Lipid Res. 2008) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3

Products for ACBD6 Gene

Sources for ACBD6 Gene

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