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ACBD4 Gene

protein-coding   GIFtS: 50
GCID: GC17P043209

Acyl-CoA Binding Domain Containing 4

(Previous name: acyl-Coenzyme A binding domain containing 4)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Acyl-CoA Binding Domain Containing 41 2
Acyl-Coenzyme A Binding Domain Containing 41 2
Acyl-CoA-Binding Domain-Containing Protein 42

External Ids:    HGNC: 233371   Entrez Gene: 797772   Ensembl: ENSG000001815137   UniProtKB: Q8NC063   
ORGUL members:         

Export aliases for ACBD4 gene to outside databases

Previous GC identifers: GC17P043685 GC17P043688 GC17P040565 GC17P038976


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ACBD4 Gene:
This gene encodes a member of the acyl-coenzyme A binding domain containing protein family. All family members
contain the conserved acyl-Coenzyme A binding domain, which binds acyl-CoA thiol esters. They are thought to play
roles in acyl-CoA dependent lipid metabolism. Multiple transcript variants encoding different isoforms have been
found for this gene. (provided by RefSeq, Oct 2008)

GeneCards Summary for ACBD4 Gene:
ACBD4 (acyl-CoA binding domain containing 4) is a protein-coding gene. GO annotations related to this gene include lipid binding and fatty-acyl-CoA binding. An important paralog of this gene is ACBD5.

UniProtKB/Swiss-Prot: ACBD4_HUMAN, Q8NC06
Function: Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA
esters




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ACBD4 gene promoter:
         Hand1   Nkx2-5   Pax-4a   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidACBD4 promoter sequence
   Search Chromatin IP Primers for ACBD4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ACBD4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.31   Ensembl cytogenetic band:  17q21.31   HGNC cytogenetic band: 17q21.31

ACBD4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACBD4 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P043209:  view genomic region     (about GC identifiers)

Start:
43,209,967 bp from pter      End:
43,221,548 bp from pter
Size:
11,582 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ACBD4_HUMAN, Q8NC06 (See protein sequence)
Recommended Name: Acyl-CoA-binding domain-containing protein 4  
Size: 268 amino acids; 30308 Da
1 PDB 3D structure from and Proteopedia for ACBD4:
2WH5 (3D)    
Secondary accessions: D3DX64 Q8IUT1 Q9H8Q4
Alternative splicing: 3 isoforms:  Q8NC06-1   Q8NC06-2   Q8NC06-3   

Explore the universe of human proteins at neXtProt for ACBD4: NX_Q8NC06

Explore proteomics data for ACBD4 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ACBD4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001129176.1  NP_001129177.1  NP_001129178.1  NP_001129179.1  NP_078998.1  

    ENSEMBL proteins: 
     ENSP00000465610   ENSP00000465484   ENSP00000381367   ENSP00000466305   ENSP00000366154  
     ENSP00000314440   ENSP00000466505   ENSP00000405969  

    ACBD4 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ACBD4

     
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    antibodies-online proteins for ACBD4 (4 products) 

     
    antibodies-online peptides for ACBD4

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    antibodies-online antibodies for ACBD4 (23 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR022408 Acyl-CoA-binding_prot_CS
     IPR014352 FERM/acyl-CoA-bd_prot_3-hlx
     IPR000582 Acyl-CoA-binding_protein

    Graphical View of Domain Structure for InterPro Entry Q8NC06

    ProtoNet protein and cluster: Q8NC06

    1 Blocks protein domain: IPB000582 Acyl-coA-binding protein

    UniProtKB/Swiss-Prot: ACBD4_HUMAN, Q8NC06
    Similarity: Contains 1 ACB (acyl-CoA-binding) domain


    Find genes that share domains with ACBD4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ACBD4_HUMAN, Q8NC06
    Function: Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA
    esters

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000062fatty-acyl-CoA binding IEA--
    GO:0008289lipid binding IEA--
         
    Find genes that share ontologies with ACBD4           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ACBD4

    miRNA
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    miRTarBase miRNAs that target ACBD4:
    hsa-mir-760 (MIRT036775)

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    4 qRT-PCR Assays for microRNAs that regulate ACBD4:
    hsa-miR-3606 hsa-miR-494 hsa-miR-921 hsa-miR-543
    SwitchGear 3'UTR luciferase reporter plasmidACBD4 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ACBD4

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    Sino Biological Human cDNA Clone for ACBD4
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACBD4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACBD4
    Addgene plasmids for ACBD4 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACBD4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ACBD4
    Interactions:

        Search GeneGlobe Interaction Network for ACBD4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for ACBD4 (ENSP000003144404) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADSLENSP000002161944STRING: ENSP00000216194
    TAZENSP000002993284STRING: ENSP00000299328
    NUP155ENSP000002314984STRING: ENSP00000231498
    CRLS1ENSP000003681404STRING: ENSP00000368140
    CLK1ENSP000003268304STRING: ENSP00000326830
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ACBD4

    Selected HMDB Compounds for ACBD4 (see all 32)    About this table
    CompoundSynonyms CAS #PubMed Ids
    (2E)-Decenoyl-CoA(E)-S-2-decenoate Coenzyme A (see all 15)10018-95-8--
    (2E)-Dodecenoyl-CoA2-trans-Dodecenoyl-Coenzyme A (see all 4)1066-12-2--
    (2E)-Hexadecenoyl-CoAtrans-2-Hexadecenoyl-CoA (see all 4)4460-95-1--
    (2E)-Octenoyl-CoA(E)-S-2-octenoate Coenzyme A (see all 16)10018-94-7--
    (2E)-Tetradecenoyl-CoA(2E)-Tetradecenoyl-Coenzyme A (see all 8)38795-33-4--
    2-Methylbutyryl-CoA2-methylbutanoyl-CoA (see all 11)6712-02-3--
    2-Methylhexanoyl-CoA2-Methylhexanoyl-CoEnzyme A (see all 5)----
    3Z-dodecenoyl-CoAS-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-dodec-3-enethioate (see all 4)2152-91-2--
    Acetyl-CoAS-Acetyl coenzyme A (see all 13)72-89-9--
    Acrylyl-CoAAcryloyl coenzyme A (see all 14)5776-58-9--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ACBD4 gene (5 alternative transcripts): 
    NM_001135704.1  NM_001135705.1  NM_001135706.1  NM_001135707.1  NM_024722.2  

    Unigene Cluster for ACBD4:

    Acyl-CoA binding domain containing 4
    Hs.110298  [show with all ESTs]
    Unigene Representative Sequence: BC022000
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000587976 ENST00000587111 ENST00000586279 ENST00000591859 ENST00000586346
    ENST00000585553 ENST00000398322(uc002iic.3) ENST00000590289 ENST00000592162
    ENST00000376955(uc002iid.2) ENST00000321854(uc002iie.3 uc002iif.3 uc010dae.3)
    ENST00000589752 ENST00000589798 ENST00000591136 ENST00000431281(uc010wjj.2)

    miRNA
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    4 qRT-PCR Assays for microRNAs that regulate ACBD4:
    hsa-miR-3606 hsa-miR-494 hsa-miR-921 hsa-miR-543
    SwitchGear 3'UTR luciferase reporter plasmidACBD4 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector (see all 5): ACBD4 (NM_001135704)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACBD4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACBD4
    Addgene plasmids for ACBD4 
    Primer
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    OriGene qPCR primer pairs and template standards for ACBD4
    OriGene qSTAR qPCR primer pairs in human, mouse for ACBD4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ACBD4
      QuantiTect SYBR Green Assays in human, mouse, rat ACBD4
      QuantiFast Probe-based Assays in human, mouse, rat ACBD4

    Additional mRNA sequence: 

    AB073387.1 AK023384.1 AK075104.1 AK296167.1 AK316359.1 BC022000.1 BC029164.1 BC041143.1 

    13 DOTS entries:

    DT.100791931  DT.100692561  DT.312454  DT.91904922  DT.100024493  DT.100024492  DT.120953439  DT.100791924 
    DT.99944856  DT.102823702  DT.120953543  DT.91733266  DT.97829494 

    Selected AceView cDNA sequences (see all 103):

    CD723958 BX487299 BQ923021 BQ880147 CB960702 BU181377 BX441433 BQ053023 
    AA877381 BF514109 BQ878143 CF593468 AI911754 AB073387 BC041143 BX372399 
    BC029164 BM701590 AI272247 AW629274 AI682700 AA621807 BF914927 BQ230721 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ACBD4 (see all 10)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c ^ 11a · 11b ^ 12 ^ 13 ^
    SP1:                                                              -           -                                   -     -                 -                     
    SP2:                                                              -           -                                   -     -                                   -   
    SP3:                                                              -           -                                   -                                         -   
    SP4:                                                                          -                                   -     -                                   -   
    SP5:                          -     -     -     -     -           -           -                                                                                 

    ExUns: 14a · 14b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for ACBD4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ACBD4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCCCTTGGG
    ACBD4 Expression
    About this image

    ACBD4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ACBD4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.110298
        Custom PCR Arrays for ACBD4
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    QuantiFast Probe-based Assays in human, mouse, rat ACBD4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACBD4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ACBD4 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Acbd41 , 5 acyl-Coenzyme A binding domain containing 41, 5 83.67(n)1
    80(a)1
      11 (66.71 cM)5
    671311  NM_025988.21  NP_080264.11 
     1031016825 
    lizard
    (Anolis carolinensis)
    Reptilia ACBD46
    acyl-CoA binding domain containing 4
    38(a)
    1 ↔ 1
    6(64898861-64931375)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC7802831 acyl-CoA binding domain containing 4-like 57.64(n)
    50.84(a)
      780283  NM_001079354.1  NP_001072822.1 
    zebrafish
    (Danio rerio)
    Actinopterygii acbd41 acyl-CoA binding domain containing 4 53.23(n)
    50.19(a)
      406368  NM_213095.1  NP_998260.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG88146
    --
    19(a)
    1 → many
    2L(2874872-2877168)
    worm
    (Caenorhabditis elegans)
    Secernentea acbp-36
    acbp-46
    (see all 3)
    Protein ACBP-4 (acbp-4) mRNA, complete cds
    (see all 3)
    34(a)
    31(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    X(10903278-10905150) WBGene00009818
    III(7308354-7308890) WBGene00018949


    ENSEMBL Gene Tree for ACBD4 (if available)
    TreeFam Gene Tree for ACBD4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ACBD4 gene
    ACBD52  
    4 SIMAP similar genes for ACBD4 using alignment to 3 protein entries:     ACBD4_HUMAN (see all proteins):
    ACBD5    DBI    BRL    ACBD7

    Find genes that share paralogs with ACBD4           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ACBD4 (see all 431)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs72107431,2
    C,F--38974649(-) TCtttC/Tttttt 3 -- us2k1 trp34Minor allele frequency- T:0.43NA WA CSA 7
    rs1466279601,2
    C--38974650(-) GAATT-/TTCTTTTT 3 -- us2k10--------
    rs1832856921,2
    --38974718(-) CCTCAG/TATCTC 3 -- us2k10--------
    rs1453555901,2
    --38974816(-) GCACA-/CCCCCC
            
    CCGCC
    3 -- cds10--------
    rs1926458911,2
    --43211912(+) GCCGAA/GGTCGG 5 -- int1 us2k10--------
    rs1421357861,2
    --43212013(+) GTGGCA/GAGCGC 5 -- int1 us2k10--------
    rs1424671731,2
    C--43212271(+) CATTT-/CCCCCC 5 -- int1 us2k10--------
    rs1880294361,2
    --43212276(+) TCCCCA/CCCTCC 5 -- int1 us2k10--------
    rs1808409051,2
    --43212358(+) GAGATA/GGAGTC 5 -- int1 us2k10--------
    rs285882121,2
    C--43212473(+) GATTAC/TAGGCG 5 -- int1 us2k10--------

    HapMap Linkage Disequilibrium report for ACBD4 (43209967 - 43221548 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for ACBD4:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2516666CNV Deletion19546169
    esv2666936CNV Deletion23128226
    esv2061968CNV Deletion18987734
    nsv908297CNV Loss21882294
    dgv3179n71CNV Loss21882294
    nsv527788CNV Loss19592680
    dgv3178n71CNV Loss21882294
    nsv908300CNV Loss21882294
    nsv828022CNV Gain20364138
    esv1790779OTHER Inversion17803354

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ACBD4           About GenesLikeMe

    Genetic Association Database (GAD): ACBD4
    Human Genome Epidemiology (HuGE) Navigator: ACBD4 (1 document)

    Export disorders for ACBD4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ACBD4 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with ACBD4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Hundreds of variants clustered in genomic loci and biological pathways affect human height. (PubMed id 20881960)1, 4 Lango Allen H....Hirschhorn J.N. (Nature 2010)
    2. Genome-wide association study identifies eight loci associated with blood pressure. (PubMed id 19430483)1, 4 Newton-Cheh C....Munroe P.B. (Nat. Genet. 2009)
    3. Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (PubMed id 15221005)1, 2 Yamada S....Nakagawara A. (Oncogene 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The genetic architecture of economic and political preferences. (PubMed id 22566634)1 Benjamin D.J....Visscher P.M. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    7. Discovery and replication of novel blood pressure genetic loci in the Women's Genome Health Study. (PubMed id 21045733)1 Ho J.E....Chasman D.I. (J. Hypertens. 2011)
    8. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79777 HGNC: 23337 AceView: ACBD4 Ensembl:ENSG00000181513 euGenes: HUgn79777
    ECgene: ACBD4 H-InvDB: ACBD4

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ACBD4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ACBD4 gene:
    Search GeneIP for patents involving ACBD4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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