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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ACBD3 Gene

protein-coding   GIFtS: 56
GCID: GC01M226332

Acyl-CoA Binding Domain Containing 3

(Previous names: golgi complex associated protein 1, 60kDa, acyl-Coenzyme...)
(Previous symbols: GOLPH1, GOCAP1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Acyl-CoA Binding Domain Containing 31 2     Golgi Phosphoprotein 12 3
GOCAP11 2 3 5     Peripheral Benzodiazepine Receptor-Associated Protein PAP72 3
GOLPH11 2 3 5     PAP72
PBR- And PKA-Associated Protein 71 2 3     Golgi Resident Protein GCP602
GCP602 3 5     PKA (RIalpha)-Associated Protein2
Acyl-Coenzyme A Binding Domain Containing 31 2     Acyl-CoA-Binding Domain-Containing Protein 33
Golgi Complex Associated Protein 1, 60kDa1 2     Golgi Complex-Associated Protein 13

External Ids:    HGNC: 154531   Entrez Gene: 647462   Ensembl: ENSG000001828277   OMIM: 6068095   UniProtKB: Q9H3P73   

Export aliases for ACBD3 gene to outside databases

Previous GC identifers: GC01M223307 GC01M222639 GC01M224399 GC01M196849


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ACBD3 Gene:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic
reticulum. The protein encoded by this gene is involved in the maintenance of Golgi structure and function
through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal
regulation of steroid formation. (provided by RefSeq, Jul 2008)

GeneCards Summary for ACBD3 Gene: 
ACBD3 (acyl-CoA binding domain containing 3) is a protein-coding gene. Diseases associated with ACBD3 include carney complex, and neuronitis. GO annotations related to this gene include fatty-acyl-CoA binding. An important paralog of this gene is TMED8.

UniProtKB/Swiss-Prot: GCP60_HUMAN, Q9H3P7
Function: Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport
between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular
Leydig cells (By similarity)

Gene Wiki entry for ACBD3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_167186.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ACBD3 gene promoter:
         Nkx3-1   Nkx3-1 v4   Pax-5   Nkx3-1 v1   MIF-1   Egr-4   GATA-1   Evi-1   Nkx3-1 v2   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidACBD3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ACBD3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACBD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42.12   Ensembl cytogenetic band:  1q42.12   HGNC cytogenetic band: 1q41

ACBD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACBD3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M226332:  view genomic region     (about GC identifiers)

Start:
226,332,380 bp from pter      End:
226,374,431 bp from pter
Size:
42,052 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GCP60_HUMAN, Q9H3P7 (See protein sequence)
Recommended Name: Golgi resident protein GCP60  
Size: 528 amino acids; 60593 Da
Subunit: Interacts with the C-terminal cytoplasmic domain of giantin/GOLGB1. Interacts with PBR and PKA regulatory
subunit RI-alpha. Does not interact with PKA regulatory subunit RI-beta nor PKA regulatory subunit RII-alpha (By
similarity)
Subcellular location: Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side (By similarity).
Mitochondrion (By similarity). Note=Also mitochondrial (via its interaction with PBR) (By similarity)
Secondary accessions: B2RB29 Q5VTJ0 Q6P9F1 Q8IZC5 Q8N4D6 Q9H6U3

Explore the universe of human proteins at neXtProt for ACBD3: NX_Q9H3P7

Explore proteomics data for ACBD3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H3P7

  • ACBD3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ACBD3 Protein Expression
    REFSEQ proteins: NP_073572.2  
    ENSEMBL proteins: 
     ENSP00000355777  

    Human Recombinant Protein Products for ACBD3: 
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    Cloud-Clone Corp. Proteins for ACBD3 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005739mitochondrion IEA--
    GO:0005794Golgi apparatus IDA--
    GO:0016021integral to membrane IEA--

    ACBD3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    AKAP: A-kinase anchor proteins

    4 InterPro protein domains:
     IPR022408 Acyl-CoA-binding_prot_CS
     IPR009038 GOLD
     IPR000582 Acyl-CoA-binding_protein
     IPR014352 FERM/acyl-CoA-bd_prot_3-hlx

    Graphical View of Domain Structure for InterPro Entry Q9H3P7

    ProtoNet protein and cluster: Q9H3P7

    1 Blocks protein domain: IPB000582 Acyl-coA-binding protein

    UniProtKB/Swiss-Prot: GCP60_HUMAN, Q9H3P7
    Domain: The GOLD domain is essential for giantin binding
    Similarity: Contains 1 ACB (acyl-CoA-binding) domain
    Similarity: Contains 1 GOLD domain


    ACBD3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GCP60_HUMAN, Q9H3P7
    Function: Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport
    between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular
    Leydig cells (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000062fatty-acyl-CoA binding IEA--
    GO:0005515protein binding IPI--
         
    ACBD3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ACBD3:
     Decreased POU5F1-GFP protein e 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ACBD3 
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    SwitchGear 3'UTR luciferase reporter plasmidACBD3 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ACBD3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Benzodiazepine Pathway, Pharmacodynamics
    Benzodiazepine Pathway, Pharmacodynamics


    1 PharmGKB Pathway for ACBD3
        Benzodiazepine Pathway, Pharmacodynamics

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ACBD3

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/13 Interacting proteins for ACBD3 (Q9H3P72, 3 ENSP000003557774) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMURF2Q9HAU42, 3MINT-61799 I2D: score=3 
    PI4KBQ9UBF82MINT-8379921 MINT-8379963 MINT-8379946 MINT-8379976
    GOLGB1Q147893, ENSP000003418484I2D: score=3 STRING: ENSP00000341848
    GOLGA3Q083783, ENSP000002047264I2D: score=1 STRING: ENSP00000204726
    MKNK1Q9BUB53I2D: score=2 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006694steroid biosynthetic process IEA--
    GO:0006810transport IEA--

    ACBD3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ACBD3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ACBD3 (GCP60)

    10/32 HMDB Compounds for ACBD3 (see all 32)    About this table
    CompoundSynonyms CAS #PubMed Ids
    (2E)-Decenoyl-CoA(E)-S-2-decenoate Coenzyme A (see all 15)10018-95-8--
    (2E)-Dodecenoyl-CoA2-trans-Dodecenoyl-Coenzyme A (see all 4)1066-12-2--
    (2E)-Hexadecenoyl-CoAtrans-2-Hexadecenoyl-CoA (see all 4)4460-95-1--
    (2E)-Octenoyl-CoA(E)-S-2-octenoate Coenzyme A (see all 16)10018-94-7--
    (2E)-Tetradecenoyl-CoA(2E)-Tetradecenoyl-Coenzyme A (see all 8)38795-33-4--
    2-Methylbutyryl-CoA2-methylbutanoyl-CoA (see all 11)6712-02-3--
    2-Methylhexanoyl-CoA2-Methylhexanoyl-CoEnzyme A (see all 5)----
    3Z-dodecenoyl-CoAS-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-dodec-3-enethioate (see all 4)2152-91-2--
    Acetyl-CoAS-Acetyl coenzyme A (see all 13)72-89-9--
    Acrylyl-CoAAcryloyl coenzyme A (see all 14)5776-58-9--

    3 Novoseek inferred chemical compound relationships for ACBD3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    benzodiazepine 76.8 13 11731621 (1), 20043945 (1), 12943713 (1), 12711385 (1) (see all 6)
    steroid 52.5 11 11731621 (3), 12943713 (2), 12711385 (2), 12692076 (1) (see all 5)
    cholesterol 32.5 8 12943713 (2), 11731621 (1), 17050526 (1), 19286473 (1)

    Search CenterWatch for drugs/clinical trials and news about ACBD3 / GCP60

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ACBD3 gene: 
    NM_022735.3  

    Unigene Cluster for ACBD3:

    Acyl-CoA binding domain containing 3
    Hs.520207  [show with all ESTs]
    Unigene Representative Sequence: AB043587
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000366812(uc001hpy.3) ENST00000464927
    miRNA
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    hsa-miR-301b hsa-miR-34c-5p hsa-miR-449b hsa-miR-519e hsa-miR-301a hsa-miR-449a hsa-miR-3666 hsa-miR-144
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    Additional mRNA sequence: 

    AB043587.2 AK025520.1 AK314468.1 BC034563.2 BC039575.1 BC045533.1 BC060792.1 

    7 DOTS entries:

    DT.415758  DT.95182169  DT.95376411  DT.100026620  DT.100692533  DT.100754839  DT.121374686 

    24/214 AceView cDNA sequences (see all 214):

    N90029 BM352997 AU279552 AI818463 AI419564 AI738902 CA394672 CK821951 
    BM994665 BU520875 CA771017 AW614186 BQ431349 BI325049 BQ020219 CR590509 
    NM_022735 BM352709 AL546667 BU786583 BF197549 BC039575 AA926728 BU153320 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ACBD3 expression in normal human tissues (normalized intensities)      ACBD3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAGTTAGGCA
    ACBD3 Expression
    About this image


    ACBD3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/29 selected tissues (see all 29) fully expand
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Blood (Hematopoietic System)    fully expand to see all 4 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
             lung ; macrophages   
             bone marrow cd34+   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Colon (Gastrointestinal Tract)    fully expand to see all 3 entries
             colon ; peripheral nerve/ganglion   
     
     Uterus (Reproductive System)    fully expand to see all 3 entries
             uterus, post-menopause ; glandular cells   

    See ACBD3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ACBD3

    SOURCE GeneReport for Unigene cluster: Hs.520207

    UniProtKB/Swiss-Prot: GCP60_HUMAN, Q9H3P7
    Tissue specificity: Ubiquitous, with highest expression in testis and ovary

        SABiosciences Custom PCR Arrays for ACBD3
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACBD3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ACBD3 gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Acbd31 , 5 acyl-Coenzyme A binding domain containing 31, 5 87.43(n)1
    89.52(a)1
      1 (84.46 cM)5
    1707601  NM_133225.31  NP_573488.21 
     1807260435 
    chicken
    (Gallus gallus)
    Aves ACBD31 acyl-CoA binding domain containing 3 80.04(n)
    85.66(a)
      421317  NM_001031043.1  NP_001026214.1 
    lizard
    (Anolis carolinensis)
    Reptilia ACBD36
    Uncharacterized protein
    82(a)
    1 ↔ 1
    1(251507794-251534476)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ040833.12   -- 79.01(n)    BJ040833.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BU492952.12   -- 74.36(n)   321222  BU492952.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG142321 CG14232 50.26(n)
    44.15(a)
      32983  NM_134504.3  NP_608348.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y41E3.71 Protein Y41E3.7 54.39(n)
    49.37(a)
      178416  NM_001047560.1  NP_001041025.1 


    ENSEMBL Gene Tree for ACBD3 (if available)
    TreeFam Gene Tree for ACBD3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ACBD3 gene
    TMED82  

    ACBD3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/885 SNPs in ACBD3 are shown (see all 885)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs777628511,2
    --196881270(+) AAAAAG/ACTTTC 1 -- int11Minor allele frequency- A:0.50NA 2
    rs357941651,2
    C--226332692(+) AAAAA-/ATCCAG 1 -- ut311Minor allele frequency- A:0.50NA 2
    rs722645151,2
    C--226333536(+) GAAGC-/CAAAA 
            
    CAAAA
    1 -- ut310--------
    rs1134335661,2
    C,F--226337973(+) CAAAAC/TGGGTT 1 -- int11Minor allele frequency- T:0.50NA 2
    rs2004426821,2
    C--226339707(+) AAAAA-/ATTTTT 1 -- int10--------
    rs340963271,2
    C--226344943(+) TTTTTT/-GAGAC 1 -- int11Minor allele frequency- -:0.00NA 2
    rs2007409511,2
    C--226345245(+) TTTTT-/TCCTCG 1 -- int10--------
    rs1998466711,2
    C--226347796(+) TTTTT-/TGAGAC 1 -- int10--------
    rs2001852511,2
    --226348027(+) CTCAA-/TCAAGTG 1 -- int10--------
    rs2001788881,2
    C--226350672(+) TTTTT-/TGTAGA 1 -- int10--------

    HapMap Linkage Disequilibrium report for ACBD3 (226332380 - 226374431 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ACBD3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2591433CNV Insertion19546169
    nsv819122CNV Loss19587683
    nsv826897CNV Loss20364138
    nsv832759CNV Loss17160897
    nsv873232CNV Gain21882294
    nsv832747CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606809    OMIM disorders: --

    2 diseases for ACBD3:    About MalaCards
    carney complex    neuronitis


    ACBD3 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for ACBD3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hypercortisolism 67 2 12943713 (1), 12692076 (1)

    Genetic Association Database (GAD): ACBD3
    Human Genome Epidemiology (HuGE) Navigator: ACBD3 (2 documents)

    Export disorders for ACBD3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ACBD3 gene, integrated from 9 sources (see all 41):
    (articles sorted by number of sources associating them with ACBD3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma. (PubMed id 18636124)1, 4 Skibola C.F....Smith M.T. (2008)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
    6. Identification and characterization of a novel Golgi protein, GCP60, that interacts with the integral membrane protein giantin. (PubMed id 11590181)1, 2 Sohda M.... Ikehara Y. (2001)
    7. Identification, localization, and function in steroidogenesis of PAP7: a peripheral-type benzodiazepine receptor- and PKA (RIalpha)-associated protein. (PubMed id 11731621)1, 9 Li H....Papadopoulos V. (2001)
    8. Molecular cloning, genomic organization, chromosomal mapping and subcellular localization of mouse PAP7: a PBR and PKA-RIalpha associated protein. (PubMed id 12711385)1, 9 Liu J....Papadopoulos V. (2003)
    9. Molecular cloning, chromosomal localization of human peripheral-type benzodiazepine receptor and PKA regulatory subunit type 1A (PRKAR1A)-associated protein PAP7, and studies in PRKAR1A mutant cells and tissues. (PubMed id 12692076)1, 9 Liu J....Papadopoulos V. (2003)
    10. ACBD3 interaction with TBC1 domain 22 protein is diffe rentially affected by enteroviral and kobuviral 3A protein binding. (PubMed id 23572552)1 Greninger A.L....DeRisi J.L. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 64746 HGNC: 15453 AceView: ACBD3 Ensembl:ENSG00000182827 euGenes: HUgn64746
    ECgene: ACBD3 H-InvDB: ACBD3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ACBD3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ACBD3 gene:
    Search GeneIP for patents involving ACBD3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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