Aliases for ACAP1 Gene
Aliases for ACAP1 Gene
External Ids for ACAP1 Gene
- HGNC: 16467
- Entrez Gene: 9744
- Ensembl: ENSG00000072818
- OMIM: 607763
- UniProtKB: Q15027
Previous HGNC Symbols for ACAP1 Gene
- CENTB1
Previous GeneCards Identifiers for ACAP1 Gene
- GC17P007181
- GC17P007239
- GC17P007133
Summaries for ACAP1 Gene
GeneCards Summary for ACAP1 Gene
ACAP1 (ArfGAP With Coiled-Coil, Ankyrin Repeat And PH Domains 1) is a Protein Coding gene. Among its related pathways are Arf6 signaling events and Arf6 trafficking events. GO annotations related to this gene include GTPase activator activity. An important paralog of this gene is ACAP2.
UniProtKB/Swiss-Prot for ACAP1 Gene
-
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ACAP1 Gene
Genomics for ACAP1 Gene
Regulatory Elements for ACAP1 Gene
Enhancers for ACAP1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ACAP1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ACAP1 gene promoter:
Regulatory Element Products
Genomic Location for ACAP1 Gene
- Chromosome:
- 17
- Start:
- 7,336,511 bp from pter
- End:
- 7,351,478 bp from pter
- Size:
- 14,968 bases
- Orientation:
- Plus strand
Genomic View for ACAP1 Gene
Genes around ACAP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17p13.1 by Ensembl
- 17p13.1 by Entrez Gene
- 17p13.1 by HGNC
ACAP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ACAP1 Gene
Proteins for ACAP1 Gene
-
Protein details for ACAP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q15027-ACAP1_HUMAN
- Recommended name:
- Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
- Protein Accession:
- Q15027
- Q53XN9
Protein attributes for ACAP1 Gene
- Size:
- 740 amino acids
- Molecular mass:
- 81536 Da
- Quaternary structure:
-
- Banana-shaped homodimer laterally assembling into tetramers, the tetramers further pack helically onto the membrane. Interacts with GTP-bound ARF6. Interacts with third cytoplasmic loop of SLC2A4/GLUT4. Interacts with CLTC. Interacts with GULP1. Forms a complex with GDP-bound ARF6 and GULP1. Interacts with ITGB1; required for ITGB1 recycling.
- Miscellaneous:
-
- Cells overexpressing ACAP1 show an accumulation of ITGB1 in recycling endosomes and inhibition of stimulation-dependent cell migration. Cells with reduced levels of ACAP1 or AKT1 and AKT2 show inhibition of stimulation-dependent cell migration. Cells overexpressing ACAP1 and PIP5K1C show formation of tubular structures derived from endosomal membranes.
- SequenceCaution:
-
- Sequence=BAA06418.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for ACAP1 Gene
Post-translational modifications for ACAP1 Gene
- Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1, export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
- Ubiquitination at posLast=4040, Lys90, posLast=114114, posLast=183183, posLast=185185, Lys218, Lys248, posLast=274274, posLast=522522, and Lys558
- Modification sites at PhosphoSitePlus
Other Protein References for ACAP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ACAP1
- Novus Biologicals Antibodies for ACAP1
- Invitrogen Antibodies for ACAP1
- antibodies-online Antibodies for ACAP1: See all 54
- GeneTex ACAP1 antibody for ACAP1
-
Santa Cruz Biotechnology (SCBT) Antibodies for ACAP1
Protein Products
-
OriGene Purified Proteins for ACAP1
- Search Origene for MassSpec and Protein Over-expression Lysates for ACAP1
- Origene Custom Protein Services for ACAP1
- antibodies-online Proteins for ACAP1: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ACAP1
Assay Products
- antibodies-online Kits for ACAP1: See all 1
No data available for DME Specific Peptides for ACAP1 Gene
Domains & Families for ACAP1 Gene
Gene Families for ACAP1 Gene
Protein Domains for ACAP1 Gene
Suggested Antigen Peptide Sequences for ACAP1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q15027UniProtKB/Swiss-Prot:
ACAP1_HUMAN :- PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate ACAP1-binding to PIP2 or PIP3 containing membranes. Only one PH domain of one ACAP1 dimer inserts into the membrane, while the other PH domain acts primaryly to interact with adjacent ACAP1 dimers.
- Domain:
-
- PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate ACAP1-binding to PIP2 or PIP3 containing membranes. Only one PH domain of one ACAP1 dimer inserts into the membrane, while the other PH domain acts primaryly to interact with adjacent ACAP1 dimers.
- The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.
Function for ACAP1 Gene
Molecular function for ACAP1 Gene
- UniProtKB/Swiss-Prot EnzymeRegulation:
- GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
- UniProtKB/Swiss-Prot Function:
- GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 17474147 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for ACAP1 Gene
- MGI mutant phenotypes for ACAP1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ACAP1:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- Increased transferrin (TF) endocytosis
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Increased epidermal growth factor receptor (EGFR) surface abundance
- Increased Sindbis virus (SINV) infection
Animal Models for ACAP1 Gene
- MGI Knock Outs for ACAP1:
-
- Acap1 tm1.1(KOMP)Vlcg
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ACAP1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ACAP1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ACAP1 gene
- Search ViGene Biosciences for ACAP1
CRISPR Products
-
OriGene CRISPR knockouts for ACAP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for ACAP1
- GenScript: Design CRISPR guide RNA sequences for ACAP1
miRNA Products
- Search ViGene Biosciences for ACAP1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ACAP1
- Browse OriGene Inhibitory RNA Products For ACAP1
-
ViGene Biosciences ready-to-package AAV shRNAs for ACAP1 gene
Clone Products
-
OriGene ORF clones in human for ACAP1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ACAP1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ACAP1
- VectorBuilder custom plasmid, inducible vectors for ACAP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACAP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ACAP1
-
ViGene Biosciences adenoviral particle packaged cDNA for ACAP1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ACAP1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ACAP1 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for ACAP1 Gene
Localization for ACAP1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ACAP1 Gene
- Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side.
| Compartment | Confidence |
|---|---|
| endosome | 4 |
| nucleus | 3 |
| cytosol | 3 |
| plasma membrane | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005768 | endosome | IEA | -- |
| GO:0016020 | membrane | IDA,IEA | 19946888 |
| GO:0043231 | intracellular membrane-bounded organelle | IDA | -- |
| GO:0055038 | recycling endosome membrane | IEA | -- |
Pathways & Interactions for ACAP1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Endocytosis | ||
| 2 | Arf6 signaling events | ||
| 3 | Arf6 trafficking events | ||
| 4 | Nucleotide-binding Oligomerization Domain (NOD) pathway | ||
Pathways by source for ACAP1 Gene
3 BioSystems pathways for ACAP1 Gene
1 KEGG pathway for ACAP1 Gene
Interacting Proteins for ACAP1 Gene
Selected Interacting proteins:
ENSP00000158762
Q15027-ACAP1_HUMAN
for ACAP1 Gene via
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | IEA | -- |
| GO:0015031 | protein transport | IEA | -- |
| GO:0043547 | positive regulation of GTPase activity | IEA | -- |
Drugs & Compounds for ACAP1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Guanosine triphosphate | Experimental | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| PA(16:0/16:0) |
|
7091-44-3 |
|
|||
| PA(16:0/18:1(11Z)) |
|
|
||||
| PA(16:0/18:1(9Z)) |
|
|
||||
| PA(16:0/18:2(9Z,12Z)) |
|
|
||||
| PA(16:0e/18:0) |
|
|
Transcripts for ACAP1 Gene
mRNA/cDNA for ACAP1 Gene
- (1) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (190) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ACAP1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ACAP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for ACAP1
- GenScript: Design CRISPR guide RNA sequences for ACAP1
miRNA Products
- Search ViGene Biosciences for ACAP1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ACAP1
- Browse OriGene Inhibitory RNA Products For ACAP1
-
ViGene Biosciences ready-to-package AAV shRNAs for ACAP1 gene
Clone Products
-
OriGene ORF clones in human for ACAP1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ACAP1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ACAP1
- VectorBuilder custom plasmid, inducible vectors for ACAP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACAP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: |
| ExUns: | 22b | ^ | 23 |
|---|---|---|---|
| SP1: | |||
| SP2: | |||
| SP3: | |||
| SP4: | |||
| SP5: | |||
| SP6: | |||
| SP7: | |||
| SP8: |
Expression for ACAP1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Inner Cell Mass (Early Embryonic Tissues)
- Bone (Muscoskeletal System)
- Thymus (Hematopoietic System)
-
Spleen (Hematopoietic System)
-
Lymph (Hematopoietic System)
mRNA differential expression in normal tissues according to GTEx for ACAP1 Gene
This gene is overexpressed in Whole Blood (x26.9) and Spleen (x6.0).
This gene is overexpressed in Lymph node (23.4), Peripheral blood mononuclear cells (15.9), Tlymphocyte (6.9), and Blymphocyte (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ACAP1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ACAP1 Gene:
ACAP1SOURCE GeneReport for Unigene cluster for ACAP1 Gene:
Hs.337242mRNA Expression by UniProt/SwissProt for ACAP1 Gene:
Q15027-ACAP1_HUMAN
Tissue specificity:
Highest level in lung and spleen. Low level in heart, kidney, liver and pancreas.
Evidence on tissue expression from TISSUES for ACAP1 Gene
- Bone marrow(4.3)
- Lymph node(2)
Primer Products
-
OriGene qPCR primer pairs for ACAP1
-
OriGene qPCR primer pairs and template standards for ACAP1
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ACAP1 Gene
Orthologs for ACAP1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ACAP1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | ACAP1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Acap1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Acap1 34 |
|
||
| dog (Canis familiaris) |
Mammalia | ACAP1 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ACAP1 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | acap1 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | cenB1A 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | cnt-1 35 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | AGE1 35 37 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for ACAP1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for ACAP1 Gene
Paralogs for ACAP1 Gene
(2) SIMAP similar genes for ACAP1 Gene using alignment to 5 proteins:
Variants for ACAP1 Gene
| SNP ID | Clin | Chr 17 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs754740225 | A colorectal cancer sample | 7,343,420(+) | CTGGC(A/G)GGGGG | nc-transcript-variant, reference, missense | |
| rs759855054 | A breast cancer sample | 7,342,471(+) | GGTCA(A/G)GGAGT | nc-transcript-variant, reference, missense | |
| rs1000043020 | -- | 7,348,840(+) | TTACA(C/T)ATACC | intron-variant | |
| rs1000119126 | -- | 7,338,510(+) | TACCT(A/G)CCGCA | intron-variant | |
| rs1000137406 | -- | 7,348,586(+) | ATGTC(A/G)GAGGG | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2422288 | CNV | deletion | 17116639 |
| esv2671173 | CNV | deletion | 23128226 |
| esv3639867 | CNV | loss | 21293372 |
| nsv1143848 | CNV | deletion | 24896259 |
| nsv457659 | CNV | loss | 19166990 |
| nsv509650 | CNV | insertion | 20534489 |
| nsv574322 | CNV | loss | 21841781 |
| nsv952118 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
58.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.61;
65.38% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ACAP1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ACAP1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ACAP1 Gene
Disorders for ACAP1 Gene
Relevant External Links for ACAP1
No disorders were found for ACAP1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ACAP1 Gene
Publications for ACAP1 Gene
- ACAPs are arf6 GTPase-activating proteins that function in the cell periphery. (PMID: 11062263) Jackson T.R. … Randazzo P.A. (J. Cell Biol. 2000) 2 3 4 22 64
- An ACAP1-containing clathrin coat complex for endocytic recycling. (PMID: 17664335) Li J. … Hsu V.W. (J. Cell Biol. 2007) 3 4 22 64
- Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry. (PMID: 16777052) Zhan X. … Desiderio D.M. (Anal. Biochem. 2006) 3 4 22 64
- Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulation. (PMID: 17010122) Shinozaki-Narikawa N. … Shibasaki Y. (Traffic 2006) 3 4 22 64
- Mechanistic insights into regulated cargo binding by ACAP1 protein. (PMID: 22645133) Bai M. … Hsu V.W. (J. Biol. Chem. 2012) 3 4 64
Products for ACAP1 Gene
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- Browse R&D Systems for biochemical assays
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- Browse Proteins and Enzymes
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- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse Immunoprecipitation Assays
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- Custom Antibody ServicesOriGene Antibodies for ACAP1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ACAP1
- Search Origene for MassSpec and Protein Over-expression Lysates for ACAP1
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- OriGene qPCR primer pairs and template standards for ACAP1
- OriGene qPCR primer pairs for ACAP1
- OriGene CRISPR knockouts for ACAP1
- OriGene ORF clones in human for ACAP1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for ACAP1 in any vector
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- GenScript: Design CRISPR guide RNA sequences for ACAP1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
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- GenScript Custom Peptide Services for ACAP1
- Sino Biological Human cDNA Clone for ACAP1
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- Novus Biologicals Antibodies for ACAP1
- Novus Biologicals proteins and lysates for ACAP1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Addgene plasmids for ACAP1
- antibodies-online Antibodies for ACAP1: See all 54
- antibodies-online Kits for ACAP1: See all 1
- antibodies-online Proteins for ACAP1: See all 5
- Search antibodies-online for peptides
- GeneTex ACAP1 antibody for ACAP1
- Search GeneTex for Proteins for ACAP1
- ViGene Biosciences adenoviral particle packaged cDNA for ACAP1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ACAP1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ACAP1 gene
- Search ViGene Biosciences for ACAP1
- Santa Cruz Biotechnology (SCBT) Antibodies for ACAP1
- Search Santa Cruz Biotechnology (SCBT) for ACAP1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ACAP1
- Horizon Cell Lines for ACAP1
- Cyagen custom Knockout/knockin (KOKI) mouse models for ACAP1
- VectorBuilder custom plasmid, inducible vectors for ACAP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ACAP1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ACAP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
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- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
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- (141) ENCODE
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