Aliases for ACADM Gene
External Ids for ACADM Gene
This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for ACADM Gene
ACADM (Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain) is a Protein Coding gene. Diseases associated with ACADM include medium-chain acyl-coenzyme a dehydrogenase deficiency and fasting hypoglycemia. Among its related pathways are Metabolism and Metabolism. GO annotations related to this gene include identical protein binding and acyl-CoA dehydrogenase activity. An important paralog of this gene is ACAD8.
UniProtKB/Swiss-Prot for ACADM Gene
This enzyme is specific for acyl chain lengths of 4 to 16