Aliases for ACADL Gene
External Ids for ACADL Gene
Previous GeneCards Identifiers for ACADL Gene
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008]
GeneCards Summary for ACADL Gene
ACADL (Acyl-CoA Dehydrogenase, Long Chain) is a Protein Coding gene. Diseases associated with ACADL include Lcad Deficiency and Hypoglycemia. Among its related pathways are Mitochondrial Fatty Acid Beta-Oxidation and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). GO annotations related to this gene include flavin adenine dinucleotide binding and fatty-acyl-CoA binding. An important paralog of this gene is ACAD8.