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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ACAD9 Gene

protein-coding   GIFtS: 54
GCID: GC03P128848

acyl-CoA dehydrogenase family, member 9

(Previous names: acyl-Coenzyme A dehydrogenase family, member 9 )
 Explore 3 diseases affiliated with
ACAD9 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ACAD9    

Aliases
for ACAD9 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Acyl-CoA Dehydrogenase Family, Member 91 2     Very-Long-Chain Acyl-CoA Dehydrogenase VLCAD2
NPD0021 2     ACAD-93
Acyl-Coenzyme A Dehydrogenase Family, Member 91 2     EC 1.3.99.-3
MGC144521     EC 1.3.998
Acyl-CoA Dehydrogenase Family Member 9, Mitochondrial2     EC 1.3.99.108

External Ids:    HGNC: 214971   Entrez Gene: 289762   Ensembl: ENSG000001776467   OMIM: 6111035   UniProtKB: Q9H8453   
ORGUL members:         
NONCODE:n409259    

Export aliases for ACAD9 gene to outside databases

Previous GC identifers: GC03P129880 GC03P129919 GC03P130081 GC03P128599 GC03P125986 GC03P128600 GC03P128671


Summaries
for ACAD9 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ACAD9:
This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the
mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is
specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA
dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.(provided by
RefSeq, Mar 2010)

UniProtKB/Swiss-Prot: ACAD9_HUMAN, Q9H845
Function: Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active
on palmitoyl-CoA than on stearoyl-CoA. Has little activity on octanoyl-CoA (C8:0), butyryl-CoA (C4:0) or
isovaleryl-CoA (5:0)

Gene Wiki entry for ACAD9


Genomic Views
for ACAD9 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ACAD9 gene promoter:
         Max1   C/EBPbeta   CUTL1   AP-4   Gfi-1   HEN1   Meis-1a   Meis-1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ACAD9 promoter sequence
   Search SABiosciences Chromatin IP Primers for ACAD9

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ACAD9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q21.3   Ensembl cytogenetic band:  3q21.3   HGNC cytogenetic band: 3q21.3

ACAD9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACAD9 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P128848:  view genomic region     (about GC identifiers)

Start:
 128,598,333 bp from pter      End:
 128,634,910 bp from pter
Size:
 36,578 bases      Orientation:
 plus strand

Proteins
for ACAD9 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ACAD9_HUMAN, Q9H845 (See protein sequence)
Recommended Name: Acyl-CoA dehydrogenase family member 9, mitochondrial precursor  
Size: 621 amino acids; 68760 Da
Cofactor: FAD (By similarity)
Subcellular location: Mitochondrion (Potential)
Secondary accessions: D3DNB8 Q8WXX3

Explore the universe of human proteins at neXtProt for ACAD9: NX_Q9H845

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H845

    • 4/5 DME Specific Peptides for ACAD9 (Q9H845) (see all 5)
     RGSNTCE  LIQEKFA  VLSRASRS  IFTVFAKT 

    ACAD9 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_054768.2  
    ENSEMBL proteins: 
     ENSP00000422020   ENSP00000312618   ENSP00000427283   ENSP00000426277   ENSP00000425226  
     ENSP00000426189   ENSP00000423758   ENSP00000425346   ENSP00000422683  

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    OriGene Purified Protein: ACAD9
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    Novus Biologicals ACAD9 Proteins
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    Uscn Proteins for ACAD9

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005739mitochondrion IDA--
    GO:0030425dendrite IDA--


    ACAD9 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for ACAD9 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ACAD9 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR006090 Acyl-CoA_Oxase/DH_1
     IPR009100 AcylCoA_DH/oxidase
     IPR013786 AcylCoA_DH/ox_N
     IPR006091 Acyl-CoA_Oxase/DH_cen-dom
     IPR006089 Acyl-CoA_DH_CS

    Graphical View of Domain Structure for InterPro Entry Q9H845

    ProtoNet protein and cluster: Q9H845

    1 Blocks protein family: IPB006089 Acyl-CoA dehydrogenase

    UniProtKB/Swiss-Prot: ACAD9_HUMAN, Q9H845
    Similarity: Belongs to the acyl-CoA dehydrogenase family


    Function
    for ACAD9 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ACAD9_HUMAN, Q9H845
    Function: Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active
    on palmitoyl-CoA than on stearoyl-CoA. Has little activity on octanoyl-CoA (C8:0), butyryl-CoA (C4:0) or
    isovaleryl-CoA (5:0)

    Enzyme Numbers (IUBMB): EC 1.3.99.102 EC 1.3.992 EC 1.3.99.-1

    miRNA
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    Inhib. RNA
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    Gene Editing
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    Clone
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003995acyl-CoA dehydrogenase activity IEA--
    GO:0050660flavin adenine dinucleotide binding IEA--


    ACAD9 for ontologies           About GeneDecksing



    Pathways & Interactions
    for ACAD9 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Glucose / Energy Metabolism
    		Glucose / Energy Metabolism1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for ACAD9
        Glucose / Energy Metabolism



    ACAD9 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ACAD9

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5/233 Interacting proteins for ACAD9 (Q9H8452, 3 ENSP000003126184) via UniProtKB, MINT, STRING, and/or I2D (see all 233)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    OTUD7BQ6GQQ93, ENSP000003581314I2D: score=2 STRING: ENSP00000358131
    CAMKK2Q96RR43I2D: score=1 
    AARS2Q5JTZ92MINT-8079030
    AASSQ9UDR52MINT-8079030
    About this table

    Drugs & Compounds
    for ACAD9 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ACAD9 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ACAD9

    10/33 HMDB Compounds for ACAD9 (see all 33)    About this table
    CompoundSynonyms CAS #PubMed Ids
    (2E)-Decenoyl-CoA(E)-S-2-decenoate Coenzyme A (see all 15)10018-95-8--
    (2E)-Dodecenoyl-CoA2-trans-Dodecenoyl-Coenzyme A (see all 4)1066-12-2--
    (2E)-Hexadecenoyl-CoAtrans-2-Hexadecenoyl-CoA (see all 4)4460-95-1--
    (2E)-Octenoyl-CoA(E)-S-2-octenoate Coenzyme A (see all 16)10018-94-7--
    (2E)-Tetradecenoyl-CoA(2E)-Tetradecenoyl-Coenzyme A (see all 8)38795-33-4--
    2-Methylbutyryl-CoA2-methylbutanoyl-CoA (see all 11)6712-02-3--
    2-Methylhexanoyl-CoA2-Methylhexanoyl-CoEnzyme A (see all 5)----
    3Z-dodecenoyl-CoAS-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-dodec-3-enethioate (see all 4)2152-91-2--
    Acetyl-CoAS-Acetyl coenzyme A (see all 13)72-89-9--
    Acrylyl-CoAAcryloyl coenzyme A (see all 14)5776-58-9--
    2 Novoseek chemical compound relationships for ACAD9 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    acyl-coa 81.7 18 17564966 (3), 16020546 (2), 16750164 (2), 12359260 (1) (see all 5)
    fatty acid 58.8 1 17564966 (1)

    Search CenterWatch for drugs/clinical trials and news about ACAD9 

    Transcripts
    for ACAD9 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ACAD9 gene: 
    NM_014049.4  

    Unigene Cluster for ACAD9:

    Acyl-CoA dehydrogenase family, member 9
    Hs.567482  [show with all ESTs]
    Unigene Representative Sequence: NR_033426
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000505602 ENST00000514643 ENST00000308982(uc011bks.2 uc003ela.4)
    ENST00000512801 ENST00000505192(uc010hsw.1) ENST00000511227 ENST00000515429
    ENST00000514336 ENST00000505867(uc003elb.3) ENST00000511526(uc003elc.1 uc003ele.3)
    ENST00000508971 ENST00000511325

    miRNA
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    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AF078854.1 AF327351.1 AK022568.1 AK024012.1 AK130311.1 AK297952.1 BC001817.2 BC007970.2 
    BC013354.2 BC041572.1 NR_033426.1 

    19 DOTS entries:

    DT.314211  DT.100670444  DT.92442134  DT.100807057  DT.92442137  DT.40225945  DT.100816868  DT.95250432 
    DT.97847826  DT.100816877  DT.91977530  DT.92442141  DT.100657416  DT.120863835  DT.120863867  DT.120863880 
    DT.92020047  DT.95250398  DT.97763702 

    24/295 AceView cDNA sequences (see all 295):

    CF541062 BQ012441 AI336918 BU167868 BQ008227 CA488487 BG674212 AK096587 
    BP357268 BM973613 BC041572 AA380312 AL697650 BC001817 BM826944 BX281102 
    BU153157 F34967 AI992143 BQ938039 AW439506 CD370922 BM552756 AA635874 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for ACAD9 (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11 ^ 12a · 12b ^ 13
    SP1:                                      -     -     -                                               -                                                   
    SP2:                                                                                                  -                                                   
    SP3:              -                       -     -     -                                               -                                                   
    SP4:              -                       -     -     -                                               -                                                   
    SP5:                                                                                                  -                                                   


    ECgene alternative splicing isoforms for ACAD9

    Expression
    for ACAD9 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ACAD9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TACCAGGAAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See ACAD9 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ACAD9

    SOURCE GeneReport for Unigene cluster: Hs.567482

    UniProtKB/Swiss-Prot: ACAD9_HUMAN, Q9H845
    Tissue specificity: Ubiquitously expressed in most normal human tissues and cancer cell lines with high level of
    expression in heart, skeletal muscles, brain, kidney and liver

        SABiosciences Expression via Pathway-Focused PCR Arrays including ACAD9: 
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    In Situ
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    Orthologs
    for ACAD9 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for ACAD9 gene from 4/16 species (see all 16)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves ACAD91 acyl-CoA dehydrogenase family, member 9 71.07(n)
    74.09(a)    		   415974  NM_001006136.1  NP_001006136.1 
    lizard
    (Anolis carolinensis)    		 Reptilia ACAD96
    		 --
    		 74(a)
    		 1 ↔ 1
    		 2(159508664-159532207)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.60572 Xenopus laevis transcribed sequence with weak similarity more 76.01(n)    BU152713.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii acad91 acyl-CoA dehydrogenase family, member 9 68.52(n)
    71.21(a)    		   724002  NM_001045307.1  NP_001038772.1 


    ENSEMBL Gene Tree for ACAD9 (if available)
    TreeFam Gene Tree for ACAD9 (if available) 

    Paralogs
    for ACAD9 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ACAD9 gene
    ACADL2  ACAD82  ACADSB2  ACAD112  GCDH2  ACADS2  ACAD102  ACADM2  
    IVD2  ACADVL2  
    7 SIMAP similar genes for ACAD9 using alignment to 9 protein entries:     ACAD9_HUMAN (see all proteins):
    ACADVL    ACADSB    ACADS    IVD    ACADM    ACAD8
    ACADL

    ACAD9 for paralogs           About GeneDecksing



    Genomic Variants
    for ACAD9 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/716 NCBI SNPs in ACAD9 are shown (see all 716)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs119227791,2
    		C,H,--125983369(+) ACATAT/CGTATA 2 -- us2k1 tfbs34Minor allele frequency- C:0.00NS EA 416
    rs557347281,2
    		C,--125983792(+) GAGCTC/GGGGAA 2 -- us2k13Minor allele frequency- G:0.04NA WA 240
    rs622681811,2
    		--125984333(+) TACAGT/CTTAGA 2 -- us2k12Minor allele frequency- C:0.02NA 122
    rs738625711,2
    		C,--125984573(+) AATTAT/CCCTTA 2 -- us2k12Minor allele frequency- C:0.04WA 120
    rs622681821,2
    		--125984704(+) TCAGCG/CGGCTG 2 -- us2k12Minor allele frequency- C:0.02NA 122
    rs7892241,2
    		C,F,A,H,--125985233(+) GGCCCC/AGGGCC 2 -- us2k127Minor allele frequency- A:0.45MN EA NS NA WA CSA 3605
    rs117123251,2
    		C,H--125985292(+) CGGCGA/GGAAGC 2 -- us2k10--------
    rs1118050921,2
    		C,--125985773(+) AGATTC/TCCCAA 2 -- nc-transcript-variantint11Minor allele frequency- T:0.50NA 2
    rs732079961,2
    		C,F,--125986112(+) CCCTGC/GCATTG 2 -- int11Minor allele frequency- G:0.06NA 120
    rs168520131,2
    		C,F,H,--125986145(+) CAAGAT/CGCTTC 2 -- int19Minor allele frequency- C:0.03NA NS EA 566

    HapMap Linkage Disequilibrium report for ACAD9 (128598333 - 128634910 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ACAD9: --
    Human Gene Mutation Database (HGMD): ACAD9

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for ACAD9 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ACAD9 for disorders           About GeneDecksing

    OMIM gene information: 611103   
    OMIM disorders: 611126  
    UniProtKB/Swiss-Prot: ACAD9_HUMAN, Q9H845
  • Defects in ACAD9 are a cause of acyl-CoA dehydrogenase family member type 9 deficiency (ACAD9 deficiency)
    • [MIM:611126]. ACAD9 deficiency patients present with episodic liver dysfunction during otherwise mild illnesses or
    cardiomyopathy, along with chronic neurologic dysfunction

    3 diseases for ACAD9:    About MalaCards
    acyl-coa dehydrogenase    tuberculosis    mycobacterium tuberculosis

    1 Novoseek disease relationship for ACAD9 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cancer 0 1 12359260 (1)

    Human Genome Epidemiology (HuGE) Navigator: ACAD9 (1 document)

    Export disorders for ACAD9 gene to outside databases

    Publications
    for ACAD9 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ACAD9 gene, integrated from 9 sources (see all 24):
    (articles sorted by number of sources associating them with ACAD9)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and functional characterization of ACAD-9, a novel member of human acyl-CoA dehydrogenase family. (PubMed id 12359260)1, 2, 3, 9 Zhang J.... Cao X. (2002)
    2. A new genetic disorder in mitochondrial fatty acid beta-oxidation: ACAD9 deficiency. (PubMed id 17564966)1, 2, 9 He M.... Vockley J. (2007)
    3. Exome sequencing identifies ACAD9 mutations as a caus e of complex I deficiency. (PubMed id 21057504)1, 3 Haack T.B....Prokisch H. (2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Acyl-CoA dehydrogenase 9 (ACAD 9) is the long-chain acyl-CoA dehydrogenase in human embryonic and fetal brain. (PubMed id 16750164)1, 9 Oey N.A....Wijburg F.A. (2006)
    7. Human acyl-CoA dehydrogenase-9 plays a novel role in the mitochondrial beta-oxidation of unsaturated fatty acids. (PubMed id 16020546)1, 9 Ensenauer R....Vockley J. (2005)
    8. Carnitine palmitoyltransferase I and Acyl-CoA dehydrogenase 9 in retina: insights of retinopathy in mitochondrial trifunctional protein defects. (PubMed id 18385088)1, 9 Roomets E....Tyni T. (2008)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing. (PubMed id 22277967)1 Calvo S.E.... Mootha V.K. (2012)

    External Searches for ACAD9 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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    Genome Databases showing ACAD9 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 28976 HGNC: 21497 AceView: ACAD9 Ensembl:ENSG00000177646 euGenes: HUgn28976
    ECgene: ACAD9 H-InvDB: ACAD9

    Other Databases showing ACAD9 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ACAD9 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ACAD9 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ACAD9 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ACAD9 gene:
    Search GeneIP for patents involving ACAD9

    GeneCards and IP:
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