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ACAD11 Gene

protein-coding   GIFtS: 49
GCID: GC03M132276

Acyl-CoA Dehydrogenase Family, Member 11

(Previous names: acyl-Coenzyme A dehydrogenase family, member 11)
  See ACAD11-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Acyl-CoA Dehydrogenase Family, Member 111 2
Acyl-Coenzyme A Dehydrogenase Family, Member 111 2
ACAD-112 3
62113 Protein2
Acyl-CoA Dehydrogenase Family Member 112
EC 1.3.99.-3

External Ids:    HGNC: 302111   Entrez Gene: 841292   Ensembl: ENSG000002403037   OMIM: 6142885   UniProtKB: Q709F03   

Export aliases for ACAD11 gene to outside databases

Previous GC identifers: GC03M133761 GC03M129656


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ACAD11 Gene:
ACAD11 (acyl-CoA dehydrogenase family, member 11) is a protein-coding gene. Diseases associated with ACAD11 include childhood leukemia. GO annotations related to this gene include long-chain-acyl-CoA dehydrogenase activity and flavin adenine dinucleotide binding. An important paralog of this gene is ACADL.

UniProtKB/Swiss-Prot: ACD11_HUMAN, Q709F0
Function: Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NC_018914.2  NT_005612.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the ACAD11 gene promoter:
         ISGF-3   CUTL1   RelA   NF-kappaB   C/EBPalpha   AREB6   POU2F1   POU2F1a   STAT3   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidACAD11 promoter sequence
   Search Chromatin IP Primers for ACAD11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ACAD11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q22.1   Ensembl cytogenetic band:  3q22.1   HGNC cytogenetic band: 3q22.1

ACAD11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ACAD11 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M132276:  view genomic region     (about GC identifiers)

Start:
132,276,982 bp from pter      End:
132,379,567 bp from pter
Size:
102,586 bases      Orientation:
minus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for ACAD11

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ACD11_HUMAN, Q709F0 (See protein sequence)
Recommended Name: Acyl-CoA dehydrogenase family member 11  
Size: 780 amino acids; 87283 Da
Cofactor: FAD
Subunit: Homodimer
Sequence caution: Sequence=BAB14158.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
1 PDB 3D structure from and Proteopedia for ACAD11:
2WBI (3D)    
Secondary accessions: Q08AF0 Q658N9 Q658Y2 Q6ZND2 Q8WUT6 Q9H9R3
Alternative splicing: 3 isoforms:  Q709F0-1   Q709F0-2   Q709F0-3   

Explore the universe of human proteins at neXtProt for ACAD11: NX_Q709F0

Explore proteomics data for ACAD11 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ACAD11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_115545.3  
    ENSEMBL proteins: 
     ENSP00000264990   ENSP00000419973   ENSP00000423796   ENSP00000420907   ENSP00000347636  
     ENSP00000446263  

    ACAD11 Human Recombinant Protein Products:

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    Novus Biologicals ACAD11 Protein
    Novus Biologicals ACAD11 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ACAD11

     
    Search eBioscience for Proteins for ACAD11 

     
    antibodies-online proteins for ACAD11 (4 products) 

     
    antibodies-online peptides for ACAD11

    ACAD11 Antibody Products:

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    antibodies-online antibodies for ACAD11 (18 products) 

    ACAD11 Assay Products:

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    Cloud-Clone Corp. ELISAs for ACAD11
    Cloud-Clone Corp. CLIAs for ACAD11
    Search eBioscience for ELISAs for ACAD11 
    antibodies-online kits for ACAD11 (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 6):
     IPR013786 AcylCoA_DH/ox_N
     IPR006091 Acyl-CoA_Oxase/DH_cen-dom
     IPR011009 Kinase-like_dom
     IPR009100 AcylCoA_DH/oxidase_NM_dom
     IPR009075 AcylCo_DH/oxidase_C

    Graphical View of Domain Structure for InterPro Entry Q709F0

    ProtoNet protein and cluster: Q709F0

    2 Blocks protein domains:
    IPB002575 Aminoglycoside phosphotransferase
    IPB008266 Tyrosine protein kinase


    UniProtKB/Swiss-Prot: ACD11_HUMAN, Q709F0
    Similarity: Belongs to the acyl-CoA dehydrogenase family


    Find genes that share domains with ACAD11           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ACD11_HUMAN, Q709F0
    Function: Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA
    Catalytic activity: Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

         Enzyme Number (IUBMB): EC 1.3.99.-1

         Gene Ontology (GO): Selected molecular function terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003995acyl-CoA dehydrogenase activity ----
    GO:0004466long-chain-acyl-CoA dehydrogenase activity IDA--
    GO:0016491oxidoreductase activity ----
    GO:0016627oxidoreductase activity, acting on the CH-CH group of donors ----
    GO:0016772transferase activity, transferring phosphorus-containing groups IEA--
         
    Find genes that share ontologies with ACAD11           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ACAD11

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat ACAD11 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate ACAD11
    SwitchGear 3'UTR luciferase reporter plasmidACAD11 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ACAD11
    Predesigned siRNA for gene silencing in human, mouse, rat ACAD11

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: ACAD11 (NM_032169)
    Sino Biological Human cDNA Clone for ACAD11
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ACAD11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ACAD11
    Addgene plasmids for ACAD11 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACAD11


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ACD11_HUMAN, Q709F0: Peroxisome (By similarity). Mitochondrion. Note=Has been detected associated with
    mitochondrial membrane, but no matrix, in kidney and cerebellum, as well as in a neuroblastoma cell line, but not
    in skin fibroblasts, where it is observed in cytoplasmic vesicles (PubMed:21237683). No mitochondrial targeting
    signals could be predicted for any known isoform, including a putative isoform starting at Met-316
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    nucleus5
    peroxisome3
    cytosol2

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005739mitochondrion ----
    GO:0005777peroxisome ISS--
    GO:0031966mitochondrial membrane IDA--

    Find genes that share ontologies with ACAD11           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Arrays including ACAD11: 
              Fatty Acid Metabolism in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for ACAD11

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for ACAD11 (Q709F03 ENSP000002649904) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    TBKBP1A7MCY63, ENSP000003547774STRING: ENSP00000354777 I2D: score=1 
    CDC42P609533I2D: score=2 
    BICD1ENSP000002814744STRING: ENSP00000281474
    BICD2ENSP000003493514STRING: ENSP00000349351
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152metabolic process ----
    GO:0033539fatty acid beta-oxidation using acyl-CoA dehydrogenase IDA--
    GO:0055114oxidation-reduction process ----

    Find genes that share ontologies with ACAD11           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ACAD11 (ACD11)

    Selected HMDB Compounds for ACAD11 (see all 32)    About this table
    CompoundSynonyms CAS #PubMed Ids
    (2E)-Decenoyl-CoA(E)-S-2-decenoate Coenzyme A (see all 15)10018-95-8--
    (2E)-Dodecenoyl-CoA2-trans-Dodecenoyl-Coenzyme A (see all 4)1066-12-2--
    (2E)-Hexadecenoyl-CoAtrans-2-Hexadecenoyl-CoA (see all 4)4460-95-1--
    (2E)-Octenoyl-CoA(E)-S-2-octenoate Coenzyme A (see all 16)10018-94-7--
    (2E)-Tetradecenoyl-CoA(2E)-Tetradecenoyl-Coenzyme A (see all 8)38795-33-4--
    2-Methylbutyryl-CoA2-methylbutanoyl-CoA (see all 11)6712-02-3--
    2-Methylhexanoyl-CoA2-Methylhexanoyl-CoEnzyme A (see all 5)----
    3Z-dodecenoyl-CoAS-[2-[3-[[(2R)-4-[[[(2R,3R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] (Z)-dodec-3-enethioate (see all 4)2152-91-2--
    Acetyl-CoAS-Acetyl coenzyme A (see all 13)72-89-9--
    Acrylyl-CoAAcryloyl coenzyme A (see all 14)5776-58-9--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ACAD11 gene: 
    NM_032169.4  

    Unigene Cluster for ACAD11:

    Acyl-CoA dehydrogenase family, member 11
    Hs.441378  [show with all ESTs]
    Unigene Representative Sequence: NM_032169
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000496418 ENST00000264990(uc003eov.4) ENST00000485198 ENST00000469042(uc011blr.1)
    ENST00000510100 ENST00000477604 ENST00000507705 ENST00000487024 ENST00000481970
    ENST00000489991 ENST00000355458 ENST00000545291
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat ACAD11
      QuantiFast Probe-based Assays in human, mouse, rat ACAD11

    Additional mRNA sequence: 

    AJ608287.1 AK022654.1 AK298627.1 AK308380.1 BC019607.1 BC125204.1 BC125205.1 

    12 DOTS entries:

    DT.85105518  DT.97780080  DT.100765440  DT.95357113  DT.95163640  DT.100765439  DT.80101417  DT.100686416 
    DT.120924339  DT.113449  DT.120924360  DT.91757901 

    Selected AceView cDNA sequences (see all 249):

    AI280266 BX280865 AK055253 AY257864 BX100542 AI564516 AL832863 BQ012452 
    BM312074 AK092910 BX118014 AL518293 CD245081 CD722999 NM_153240 AI140721 
    AK022654 AI079955 BQ425843 BQ925721 AI619987 BU629196 NM_032169 AU125268 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ACAD11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCTCCAGCC
    ACAD11 Expression
    About this image

    ACAD11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ACAD11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.441378

    UniProtKB/Swiss-Prot: ACD11_HUMAN, Q709F0
    Tissue specificity: Widely expressed with highest levels in brain followed by liver, heart and kidney

        Pathway & Disease-focused RT2 Profiler PCR Arrays including ACAD11: 
              Fatty Acid Metabolism in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ACAD11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ACAD11 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Acad111 , 5 acyl-Coenzyme A dehydrogenase family, member 111, 5 81.17(n)1
    81.09(a)1
      9 (56.25 cM)5
    1026321  NM_175324.31  NP_780533.21 
     1040406625 
    chicken
    (Gallus gallus)
    Aves ACAD111 acyl-CoA dehydrogenase family, member 11 71.73(n)
    70.39(a)
      420689  NM_001006367.1  NP_001006367.1 
    lizard
    (Anolis carolinensis)
    Reptilia ACAD116
    acyl-CoA dehydrogenase family, member 11
    67(a)
    1 ↔ 1
    6(38147455-38193009)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia acad111 acyl-CoA dehydrogenase family, member 11 65.68(n)
    67.14(a)
      100486957  XM_002937737.2  XP_002937783.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc558352 hypothetical protein MGC55835 72.09(n)   393147  BC045470.1 
    A. gossypii yeast
    (Ashbya gossypii)
    Saccharomycetes AGOS_AFL213W1 AGOS_AFL213W 41.95(n)
    32(a)
      4621561  NM_210691.2  NP_985337.1 
    soybean
    (Glycine max)
    eudicotyledons BI699561.12   -- 72.92(n)    BI699561.1 
    wheat
    (Triticum aestivum)
    Liliopsida Ta.256992 Triticum aestivum transcribed sequence with weak similarity more 72.35(n)    CD918658.1 


    ENSEMBL Gene Tree for ACAD11 (if available)
    TreeFam Gene Tree for ACAD11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ACAD11 gene
    ACADL2  ACADSB2  ACAD82  GCDH2  ACADS2  ACAD92  ACADM2  ACAD102  
    IVD2  ACADVL2  
    3 SIMAP similar genes for ACAD11 using alignment to 5 protein entries:     ACD11_HUMAN (see all proteins):
    ACAD10    ACADM    ACADS

    Find genes that share paralogs with ACAD11           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    2 SNPs for ACAD11    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs67765761,2,4
    ----see VAR_0288262 mis40--------
    rs8215721,2,4
    ----see VAR_0288252 mis40--------

    HapMap Linkage Disequilibrium report for ACAD11 (132276982 - 132379567 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ACAD11:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2675190CNV Deletion23128226
    esv2669271CNV Deletion23128226
    nsv829728CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ACAD11
    DNA2.0 Custom Variant and Variant Library Synthesis for ACAD11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614288    OMIM disorders: --

    1 disease for ACAD11:    
    About MalaCards
    childhood leukemia


    Find genes that share disorders with ACAD11           About GenesLikeMe

    Genetic Association Database (GAD): ACAD11
    Human Genome Epidemiology (HuGE) Navigator: ACAD11 (6 documents)

    Export disorders for ACAD11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ACAD11 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with ACAD11)
        Utopia: connect your pdf to the dynamic
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    1. Identification and characterization of new long chain acyl-CoA dehydrogenases. (PubMed id 21237683)1, 2 He M.... Vockley J. (Mol. Genet. Metab. 2011)
    2. Polymorphisms in innate immunity genes and risk of childhood leukemia. (PubMed id 20438785)1, 4 Han S....Kang D. (Hum. Immunol. 2010)
    3. Risk of meningioma and common variation in genes related to innate immunity. (PubMed id 20406964)1, 4 Rajaraman P....Inskip P.D. (amp 2010)
    4. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    8. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S.... Dorf M.E. (Immunity 2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid beta-oxidation in peroxisomal matrix. (PubMed id 22002062)1 Okumoto K.... Fujiki Y. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84129 HGNC: 30211 AceView: FLJ12592andNPHP3 Ensembl:ENSG00000240303 euGenes: HUgn84129
    ECgene: ACAD11 H-InvDB: ACAD11

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ACAD11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ACAD11 gene:
    Search GeneIP for patents involving ACAD11

    GeneCards and IP:
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